{"id":96233,"date":"2023-09-27T20:48:00","date_gmt":"2023-09-27T13:48:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023092720480096233"},"modified":"2023-09-28T15:54:52","modified_gmt":"2023-09-28T07:54:52","slug":"sirnaomics%e9%a6%99%e6%b8%af%e5%9b%bd%e9%99%85%e7%94%9f%e7%89%a9%e5%b1%95%e7%89%b9%e9%82%80%e4%b8%93%e9%a2%98%e8%ae%ba%e5%9d%9b%e5%9c%86%e6%bb%a1%e4%b8%be%e8%a1%8c","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023092720480096233","title":{"rendered":"Sirnaomics\u9999\u6e2f\u56fd\u9645\u751f\u7269\u5c55\u7279\u9080\u4e13\u9898\u8bba\u575b\u5706\u6ee1\u4e3e\u884c"},"content":{"rendered":"

\u9999\u6e2f\u3001\u9a6c\u91cc\u5170\u5dde\u5fb7\u56fd\u57ce\u548c\u82cf\u5dde<\/span>2023\u5e749\u670827\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u884c\u4e1a\u9886\u5148\u7684\u4e13\u6ce8\u4e8e\u7814\u53d1\u53ca\u521b\u5236RNAi\u836f\u7269\u7684\u751f\u7269\u5236\u836f\u516c\u53f8 Sirnaomics Ltd.<\/b>\uff08"\u516c\u53f8"\uff0c\u8fde\u540c\u5176\u9644\u5c5e\u516c\u53f8\uff0c\u7edf\u79f0"\u96c6\u56e2"\u6216"Sirnaomics"\uff1b\u80a1\u4efd\u4ee3\u53f7\uff1a2257\uff09\u5ba3\u5e03\u7531\u9999\u6e2f\u751f\u7269\u79d1\u6280\u534f\u4f1a\u4e3b\u529e\u3001Sirnaomics\u96c6\u56e2\u534f\u529e\u7684"RNA\u836f\u7269\uff1a\u7597\u6cd5\u3001\u75ab\u82d7\u4e0e\u672a\u6765"\u9999\u6e2f\u56fd\u9645\u751f\u7269\u5c55\u7279\u9080\u4e13\u9898\u8bba\u575b\u4e8e9\u670813\u65e5\u6210\u529f\u4e3e\u884c\u3002\u5341\u4e8c\u4f4d\u56fd\u5185\u5916\u9886\u519b\u751f\u7269\u6280\u672f\u4f01\u4e1a\u7684\u7ba1\u7406\u5c42\u3001\u77e5\u540d\u5b66\u8005\u53ca\u6743\u5a01\u4e13\u5bb6\uff0c\u5728\u8bba\u575b\u4e0a\u5bf9\u903e\u4e8c\u767e\u4f4d\u542c\u4f17\uff0c\u5c31\u63a2\u7d22\u6709\u6548\u5b89\u5168\u7684 RNA \u7597\u6cd5\u4ea7\u54c1\u8fdb\u884c\u5206\u4eab\u3002<\/p>\n

\n

\"\"<\/a>
<\/span><\/p>\n<\/p><\/div>\n

\u8bba\u575b\u4f0a\u59cb\uff0cSirnaomics<\/b>\u6267\u884c\u8463\u4e8b\u517c\u9996\u5e2d\u6218\u7565\u5b98\u6234\u6653\u7545\u535a\u58eb<\/b>\u5c31\u8fce\u63a5 RNA \u7597\u6cd5\u65b0\u65f6\u4ee3\uff0c\u5927\u6e7e\u533a\u751f\u7269\u5236\u836f\u521b\u65b0\u81f4\u6b22\u8fce\u8f9e\uff0c\u4ed6\u8868\u793a\uff1a"RNAi\u7597\u6cd5\u8fd1\u5e74\u6765\u5728\u6cbb\u7597\u4eba\u7c7b\u73b0\u6709\u75be\u75c5\u65b9\u9762\u5448\u73b0\u51fa\u524d\u6240\u672a\u6709\u7684\u6709\u6548\u6027\uff0c\u5176\u5bf9\u4e8e\u4eba\u7c7b\u793e\u4f1a\u81f3\u5173\u91cd\u8981\u3002\u6839\u636e\u76ee\u524d\u7684\u4e0d\u5b8c\u6574\u7edf\u8ba1\uff0c\u4e2d\u56fd\u6709\u903e\u4e00\u767e\u5bb6\u4e13\u6ce8\u4e8eRNA\u7597\u6cd5\u7684\u516c\u53f8\uff0c\u7edd\u5927\u591a\u6570\u4e3a\u521d\u521b\u4f01\u4e1a\uff0c\u8bc1\u660eRNA\u9886\u57df\u5df2\u5438\u5f15\u4e86\u4e0d\u5c11\u4f01\u4e1a\u8d44\u6e90\uff0c\u53d1\u5c55\u8d8b\u52bf\u5341\u5206\u84ec\u52c3\u3002\u540c\u65f6\uff0c\u6b63\u56e0\u56fd\u5185RNA\u9886\u57df\u5e7f\u5e03\u65b0\u5174\u529b\u91cf\uff0c\u4e1a\u5185\u5bf9\u4e00\u4e9b\u4ea7\u54c1\u540e\u671f\u7814\u53d1\u7684\u7ecf\u9a8c\u6307\u5bfc\u4e0e\u5206\u4eab\u66f4\u4e3a\u6e34\u6c42\uff0c\u6545\u6211\u4eec\u5e0c\u671b\u53ef\u4ee5\u85c9\u6b64\u673a\u4f1a\u4e0e\u672c\u6b21\u8bba\u575b\u96c6\u7ed3\u7684\u884c\u4e1a\u7fd8\u695a\u3001\u4e13\u5bb6\u53ca\u5b66\u8005\uff0c\u4e00\u540c\u63a2\u8ba8RNAi\u7597\u6cd5\u7814\u53d1\u3001CMC\u53ca\u6218\u7565\u65b9\u9762\u7684\u7ecf\u9a8c\u4e0e\u5b66\u8bc6\u3002"<\/p>\n

Sirnaomics\u4f5c\u4e3a\u5f00\u53d1\u57fa\u4e8e RNA \u7597\u6cd5\u836f\u7269\u7684\u9886\u519b\u4f01\u4e1a\u4e4b\u4e00\uff0c\u4e0e\u9999\u6e2f\u56fd\u9645\u751f\u7269\u5c55\u534f\u529e\u8bba\u575b\u4ee5\u8ba8\u8bba\u5f00\u53d1\u65b0\u7684\u7597\u6cd5\u5e94\u5bf9\u4e0b\u4e00\u4ee3 RNA \u836f\u7269\u4e8e\u751f\u4ea7\u65b9\u9762\u7684\u6311\u6218\uff0c\u63a2\u7d22\u5c31\u6bcf\u5e74\u5bfc\u81f4\u6570\u767e\u4e07\u4eba\u6b7b\u4ea1\u7684\u75be\u75c5\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\u7684\u53ef\u80fd\u6027\uff0c\u4ece\u800c\u6fc0\u53d1\u751f\u4ea7RNA\u7597\u6cd5\u65b0\u4ea7\u54c1\u7684\u7075\u611f\uff0c\u540c\u65f6\u9884\u9632\u672a\u6765\u5927\u578b\u6d41\u884c\u75be\u75c5\u6216\u5176\u5b83\u536b\u751f\u5371\u673a\u7684\u51b2\u51fb\u3002Sirnaomics\u9996\u5e2d\u5236\u9020\u5b98\u738b\u6c38\u7965\u535a\u58eb\u3001\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u5f00\u53d1\u9ad8\u7ea7\u526f\u603b\u88c1 Francois Lebel\u535a\u58eb\u3001CMC\u526f\u603b\u88c1Richard W. Welch\u535a\u58eb\u3001\u96c6\u56e2\u5b50\u516c\u53f8RNAimmune\u9996\u5e2d\u6267\u884c\u5b98\u517c\u603b\u88c1\u6c88\u680b\u535a\u58eb\u3001\u5065\u65b0\u539f\u529b\u603b\u88c1\u674e\u7389\u73b2\u535a\u58eb\u53ca\u5e7f\u5dde\u9510\u535a\u5236\u836f\u526f\u603b\u88c1\u5f20\u8d85\u6210\u5148\u751f\u5e94\u9080\u51fa\u5e2d\u5e76\u5c31RNAi\u7597\u6cd5\u4e34\u5e8a\u5f00\u53d1\u3001\u751f\u4ea7\u53ca\u5546\u4e1a\u5316\u8fdb\u884c\u5206\u4eab\u3002<\/p>\n

\u5176\u4e2d\uff0cSirnaomics<\/b>\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u5f00\u53d1\u9ad8\u7ea7\u526f\u603b\u88c1<\/b> Francois Lebel<\/b>\u535a\u58eb<\/b>\u5177\u6709\u903e30\u5e74\u7684\u56fd\u9645\u751f\u7269\u5236\u836f\u5de5\u4f5c\u7ecf\u9a8c\uff0c\u5176\u8d1f\u8d23\u8bbe\u8ba1\u5e76\u7ba1\u7406\u7684\u56fd\u9645\u7814\u53d1\u9879\u76ee\u5df2\u6210\u529f\u83b7\u5f97\u591a\u4e2a\u4ea7\u54c1\u7684\u4e0a\u5e02\u8bb8\u53ef\u3002\u5176\u5c31\u57fa\u4e8e\u591a\u80bd\u7eb3\u7c73\u9897\u7c92\u9012\u9001\u5e73\u53f0\u53caGalNAc\u9012\u9001\u5e73\u53f0\u7684RNAi\u7597\u6cd5\u4ea7\u54c1\u7684\u4e34\u5e8a\u5f00\u53d1\u8fdb\u884c\u5206\u4eab\uff1a"\u7531\u4e8e\u76ee\u524d\u5e02\u9762\u4e0a\u90e8\u5206\u5c0f\u578b\u516c\u53f8\u7684\u7814\u53d1\u66f4\u52a0\u4fa7\u91cd\u4e8e\u67d0\u4e9b\u7279\u5b9a\u75be\u75c5\uff0c\u5176\u672a\u6765\u5546\u4e1a\u5316\u540e\u7684\u5e02\u573a\u6f5c\u529b\u5c06\u53d7\u5230\u5c40\u9650\u3002\u800c\u5f53\u4e0bRNAi\u7597\u6cd5\u4f5c\u4e3a\u84dd\u6d77\u5e02\u573a\uff0c\u552f\u6709\u9769\u65b0\u7684\u9012\u9001\u5e73\u53f0\u6280\u672f\uff0c\u62d3\u5c55\u9002\u5e94\u75c7\u9886\u57df\uff0c\u65b9\u80fd\u8ba9\u516c\u53f8\u53d1\u5c55\u884c\u7a33\u81f4\u8fdc\u3002"<\/p>\n

\u5728\u5706\u684c\u8ba8\u8bba\u73af\u8282\uff0cSirnaomics<\/b>\u6267\u884c\u8463\u4e8b\u517c\u9996\u5e2d\u6218\u7565\u5b98\u6234\u6653\u7545\u535a\u58eb<\/b>\u62c5\u4efb\u4e3b\u6301\uff0c\u5706\u56e0\u751f\u7269\u9996\u5e2d\u5546\u52a1\u5b98\u5434\u654f\u535a\u58eb\u3001\u534e\u6da6\u6b63\u5927\u751f\u547d\u79d1\u5b66\u57fa\u91d1\u8463\u4e8b\u603b\u7ecf\u7406\u67f3\u8fbe\u5148\u751f\u3001Sirnaomics\u5b50\u516c\u53f8EDIRNA\u9996\u5e2d\u6267\u884c\u5b98Christopher Kennedy \u5148\u751f\u4ee5\u53ca\u9999\u6e2f\u5927\u5b66\u8bb2\u5ea7\u6559\u6388\u4e07\u94a7\u535a\u58eb\u7b49\u4e00\u4f17\u5609\u5bbe\uff0c\u4e0e\u89c2\u4f17\u5206\u4eab\u5176\u4e8eRNA\u6295\u8d44\u4e0e\u672a\u6765\u5408\u4f5c\u7684\u4e13\u4e1a\u89c1\u89e3\u3002<\/p>\n

Sirnaomics<\/b>\u521b\u59cb\u4eba\u3001\u6267\u884c\u8463\u4e8b\u3001\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u9646\u9633\u535a\u58eb<\/b>\u4e8e\u95ed\u5e55\u81f4\u8f9e\u4e2d\u603b\u7ed3\uff1a"\u6211\u4eec\u5728\u672c\u6b21\u8bba\u575b\u4e2d\u900f\u8fc7\u5404\u4e2a\u4e0d\u540c\u7684\u89d2\u5ea6\u5bf9\u5c0f\u6838\u9178\u7597\u6cd5\u8fdb\u884c\u4e86\u6df1\u5ea6\u63a2\u8ba8\uff0c\u7531\u6b64\u6211\u4eec\u786e\u4fe1RNA\u7597\u6cd5\u6b63\u5728\u5f15\u9886\u65b0\u4e00\u8f6e\u7684\u751f\u7269\u79d1\u6280\u6d6a\u6f6e\uff0c\u800c\u9999\u6e2f\u4f5c\u4e3a\u521b\u79d1\u56fd\u9645\u5927\u90fd\u4f1a\u4ea6\u7d27\u8ddf\u6f6e\u6d41\u5e76\u80a9\u800c\u8d77\uff0c\u5229\u7528\u5168\u7403\u82f1\u624d\u805a\u9999\u6c5f\u4e4b\u4f18\u52bf\uff0c\u4e3a\u9999\u6e2f\u79d1\u6280\u8c31\u65b0\u7bc7\u3002"<\/p>\n

\u6b64\u5916\uff0cSirnaomics\u96c6\u56e2\u9996\u5e2d\u8d22\u52a1\u5b98\u53f6\u6c38\u57fa\u5148\u751f\u4ea6\u53d7\u9080\u53c2\u52a0\u4e8e9\u670815\u65e5\u4e3e\u529e\u7684\u5706\u684c\u8ba8\u8bba"\u5bfb\u627e\u4e0b\u4e00\u4e2a\u751f\u547d\u79d1\u5b66\u72ec\u89d2\u517d"\uff0c\u5171\u540c\u63a2\u8ba8\u65b0\u5174\u751f\u547d\u79d1\u6280\u9886\u57df\u4e2d\u7684\u7ecf\u6d4e\u673a\u9047\u4e0e\u6295\u8d44\u6f5c\u529b\u3002<\/p>\n

\u5173\u4e8e<\/u><\/b>BIOHK2023
<\/u><\/b>\u9999\u6e2f\u751f\u7269\u79d1\u6280\u534f\u4f1a\uff08HKBIO\uff09\u6210\u7acb\u4e8e2010\u5e74\uff0c\u662f\u4e00\u4e2a\u7531\u77e5\u540d\u7684\u4e1a\u754c\u548c\u5b66\u672f\u754c\u4ee3\u8868\u7ec4\u6210\u7684\u975e\u8425\u5229\u6027\u7ec4\u7ec7\uff0c\u81f4\u529b\u4e8e\u63a8\u52a8\u9999\u6e2f\u6210\u4e3a\u4e9a\u6d32\u7684\u751f\u7269\u6280\u672f\u4e2d\u5fc3\u3002BIOHK2023\uff08\u9999\u6e2f\u56fd\u9645\u751f\u7269\u79d1\u6280\u8bba\u575b\u66a8\u5c55\u89c8\uff09\u662f\u7531HKBIO\u7ec4\u7ec7\u7684\u56fd\u9645\u4f1a\u8bae\uff0c\u4ecb\u7ecd\u6765\u81ea\u5168\u7403\u5404\u5730\u7684\u6700\u5148\u8fdb\u7684\u521b\u65b0\u751f\u7269\u6280\u672f\uff0c\u662f\u4e9a\u6d32\u89c4\u6a21\u6700\u5927\u7684\u751f\u7269\u79d1\u6280\u5927\u4f1a\uff0c\u65e8\u5728\u4ecb\u7ecd\u5168\u7403\u6700\u5148\u8fdb\u7684\u751f\u7269\u79d1\u6280\u521b\u65b0\u6210\u679c\uff0c\u6c47\u805a\u5168\u7403\u751f\u7269\u79d1\u6280\u884c\u4e1a\uff0c\u56e2\u7ed3\u4f01\u4e1a\u5bb6\u3001\u6295\u8d44\u8005\u548c\u884c\u4e1a\u7231\u597d\u8005\uff0c\u521b\u9020\u65e0\u4e0e\u4f26\u6bd4\u7684\u4ea4\u6d41\u673a\u4f1a\u3002<\/p>\n

\u5173\u4e8e<\/u><\/b>Sirnaomics Ltd. (<\/u><\/b>\u80a1\u4efd\u4ee3\u53f7<\/u><\/b>: 2257)
<\/u><\/b>Sirnaomics\u662f\u4e00\u5bb6RNA\u7597\u6cd5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u516c\u53f8\u5019\u9009\u4ea7\u54c1\u5904\u4e8e\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1\u521b\u65b0\u836f\u7269\uff0c\u7528\u4e8e\u6cbb\u7597\u5177\u6709\u533b\u7597\u9700\u6c42\u53ca\u5e9e\u5927\u5e02\u573a\u673a\u4f1a\u7684\u9002\u5e94\u75c7\u3002Sirnaomics\u662f\u9996\u5bb6\u4e8e\u4e9a\u6d32\u548c\u7f8e\u56fd\u5747\u62e5\u6709\u91cd\u8981\u5e02\u573a\u5730\u4f4d\u7684\u4e34\u5e8a\u9636\u6bb5RNA\u7597\u6cd5\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u51ed\u501f\u5176\u4e13\u6709\u7684\u9012\u9001\u6280\u672f\uff1a\u591a\u80bd\u7eb3\u7c73\u9897\u7c92\u9012\u9001\u5e73\u53f0\u548c\u7b2c\u4e8c\u4ee3GalNAc\u5076\u8054\u7269\u9012\u9001\u5e73\u53f0\uff0c\u672c\u96c6\u56e2\u5df2\u5efa\u7acb\u975e\u5e38\u4e30\u5bcc\u7684\u5019\u9009\u836f\u7269\u7ba1\u7ebf\u3002\u968f\u7740\u5176STP705\u548cSTP707\u7684\u4e34\u5e8a\u9879\u76ee\u53d6\u5f97\u591a\u9879\u6210\u529f\uff0cSirnaomics\u76ee\u524d\u5728\u63a8\u8fdb\u80bf\u7624\u6cbb\u7597\u7684RNAi\u836f\u7269\u65b9\u9762\u5904\u4e8e\u56fd\u9645\u9886\u5148\u5730\u4f4d\u3002STP122G\u662f\u9996\u6b3e\u8fdb\u5165\u4e34\u5e8a\u7814\u53d1\u9636\u6bb5\u7684GalAhead™\u6280\u672f\u5019\u9009\u836f\u7269\u3002\u968f\u7740Sirnaomics\u4e34\u5e8a\u751f\u4ea7\u8bbe\u65bd\u7684\u5efa\u7acb\uff0c\u672c\u96c6\u56e2\u76ee\u524d\u6b63\u5728\u5b9e\u73b0\u4ece\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u5236\u836f\u516c\u53f8\u7684\u8dc3\u8fdb\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u516c\u53f8\u4fe1\u606f\uff0c\u53ef\u6d4f\u89c8\uff1awww.sirnaomics.com<\/a>\u3002<\/p>\n

\u5173\u4e8e<\/u><\/b>RNAimmune
<\/u><\/b>RNAimmune\uff08\u8fbe\u5195\u751f\u7269\uff09\u662f\u4e00\u5bb6\u540c\u65f6\u5728\u4e2d\u7f8e\u4e24\u5730\u6df1\u5ea6\u5e03\u5c40\u7684\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8emRNA\u75ab\u82d7\u4ee5\u53ca\u65b0\u578b\u836f\u7269\u521b\u65b0\u7814\u53d1\uff0c\u5176\u5168\u7403\u603b\u90e8\u4f4d\u4e8e\u7f8e\u56fd\u9a6c\u91cc\u5170\u5dde\uff0c\u4e2d\u56fd\u603b\u90e8\u4f4d\u4e8e\u5e7f\u5dde\u56fd\u9645\u751f\u7269\u5c9b\u3002\u8fbe\u5195\u751f\u7269\u7684\u79d1\u6280\u521b\u65b0\u5e73\u53f0\u5305\u62ec\u4e86\u81ea\u4e3b\u5f00\u53d1\u7684\u4eba\u5de5\u667a\u80fd\u65b0\u751f\u6297\u539f\u9884\u6d4b\u548c\u9a8c\u8bc1\u7b97\u6cd5ALEPVA\u6240\u6d89\u53ca\u7684\u6838\u9178\u5e8f\u5217\u548c\u8102\u8d28\u7eb3\u7c73\uff08LNP\uff09\u8f7d\u4f53\u9012\u9001\u7cfb\u7edf\uff0c\u6b64\u5916\u8fd8\u5df2\u83b7\u5f97\u4e86\u6765\u81eaSirnaomics Ltd.\u4e13\u6709\u591a\u80bd\u8102\u8d28\u7eb3\u7c73\u7c92\u5b50\uff08PLNP\uff09\u6280\u672f\u7684\u5168\u7403\u72ec\u5bb6\u6743\u5229\uff0c\u7528\u4e8emRNA\u9012\u9001\u3002\u8fbe\u5195\u751f\u7269\u5df2\u94fa\u8bbe\u4e86\u591a\u4e2amRNA\u75ab\u82d7\u548c\u836f\u7269\u7ba1\u7ebf\uff0c\u5305\u62ec\u611f\u67d3\u6027\u75be\u75c5\u75ab\u82d7\uff08\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u3001\u6d41\u611f\u75c5\u6bd2\u3001\u5e26\u72b6\u75b1\u75b9\u75c5\u6bd2\u548c\u547c\u5438\u9053\u5408\u80de\u75c5\u6bd2\u7b49\uff09\u3001\u80bf\u7624\u75ab\u82d7\uff08RAS\u3001NY-ESO-1\uff09\u4ee5\u53ca\u86cb\u767d\u66ff\u4ee3\u6cbb\u7597\u836f\u7269\u7b49\u3002\u516c\u53f8\u6781\u5177\u53d1\u5c55\u6f5c\u529b\uff0c\u9010\u6e10\u6210\u4e3amRNA\u75ab\u82d7\u53ca\u836f\u7269\u7814\u53d1\u8d5b\u9053\u91cc\u7684\u9886\u5148\u4f01\u4e1a\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u516c\u53f8\u4fe1\u606f\uff0c\u8bf7\u6d4f\u89c8\uff1awww.rnaimmune.com<\/a>\u3002<\/p>\n

\u5173\u4e8e<\/u><\/b>EDIRNA
<\/u><\/b>EDIRNA\u662f\u4e00\u5bb6\u79c1\u8425\u521b\u65b0\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u5229\u7528RNA\u7f16\u8f91\u6280\u672f\u63a2\u7d22\u53ca\u5f00\u53d1\u65b0\u578b\u6cbb\u7597\u836f\u7269\u3002\u8be5\u516c\u53f8\u7684\u4f7f\u547d\u662f\uff1a\u5229\u7528\u521b\u65b0\u7684RNA\u7f16\u8f91\u6280\u672f\u4e8e\u5168\u7403\u8303\u56f4\u5185\u63a2\u7d22\u53ca\u5f00\u53d1\u65b0\u578bRNA\u836f\u7269\u3002\u8be5\u516c\u53f8\u7684Edit-to-Cure Therapeutics™\u9012\u9001\u5e73\u53f0\u4f7f\u7528RNA\u7f16\u8f91\u6280\u672f\u89e3\u51b3\u75be\u75c5\u53d1\u5c55\u7684\u6839\u672c\u539f\u56e0\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u516c\u53f8\u4fe1\u606f\uff0c\u53ef\u6d4f\u89c8\uff1awww.EDIRNA.us<\/a>\u3002<\/p>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

\u9999\u6e2f\u3001\u9a6c\u91cc\u5170\u5dde\u5fb7\u56fd\u57ce\u548c\u82cf\u5dde2023\u5e749\u670827\u65e5 \/\u7f8e\u901a\u793e\/ — \u884c\u4e1a\u9886\u5148\u7684\u4e13\u6ce8\u4e8e\u7814\u53d1\u53ca\u521b\u5236RNAi\u836f\u7269\u7684\u751f\u7269\u5236\u836f\u516c\u53f8 Sirnaomics Ltd.\uff08"\u516c\u53f8"\uff0c\u8fde\u540c\u5176\u9644\u5c5e\u516c\u53f8\uff0c\u7edf\u79f0"\u96c6\u56e2"\u6216"Sirnaomics"\uff1b\u80a1\u4efd\u4ee3\u53f7\uff1a2257\uff09\u5ba3\u5e03\u7531\u9999\u6e2f\u751f\u7269\u79d1\u6280\u534f\u4f1a\u4e3b\u529e\u3001Sirnaomics\u96c6\u56e2\u534f\u529e\u7684"RNA\u836f\u7269\uff1a\u7597\u6cd5\u3001\u75ab\u82d7\u4e0e\u672a\u6765"\u9999\u6e2f\u56fd\u9645\u751f\u7269\u5c55\u7279\u9080\u4e13\u9898\u8bba\u575b\u4e8e9\u670813\u65e5\u6210\u529f\u4e3e\u884c\u3002\u5341\u4e8c\u4f4d\u56fd\u5185\u5916\u9886\u519b\u751f\u7269\u6280\u672f\u4f01\u4e1a\u7684\u7ba1\u7406\u5c42\u3001\u77e5\u540d\u5b66\u8005\u53ca\u6743\u5a01\u4e13\u5bb6\uff0c\u5728\u8bba\u575b\u4e0a\u5bf9\u903e\u4e8c\u767e\u4f4d\u542c\u4f17\uff0c\u5c31\u63a2\u7d22\u6709\u6548\u5b89\u5168\u7684 RNA \u7597\u6cd5\u4ea7\u54c1\u8fdb\u884c\u5206\u4eab\u3002 \u8bba\u575b\u4f0a\u59cb\uff0cSirnaomics\u6267\u884c\u8463\u4e8b\u517c\u9996\u5e2d\u6218\u7565\u5b98\u6234\u6653\u7545\u535a\u58eb\u5c31\u8fce\u63a5 RNA \u7597\u6cd5\u65b0\u65f6\u4ee3\uff0c\u5927\u6e7e\u533a\u751f\u7269\u5236\u836f\u521b\u65b0\u81f4\u6b22\u8fce\u8f9e\uff0c\u4ed6\u8868\u793a\uff1a"RNAi\u7597\u6cd5\u8fd1\u5e74\u6765\u5728\u6cbb\u7597\u4eba\u7c7b\u73b0\u6709\u75be\u75c5\u65b9\u9762\u5448\u73b0\u51fa\u524d\u6240\u672a\u6709\u7684\u6709\u6548\u6027\uff0c\u5176\u5bf9\u4e8e\u4eba\u7c7b\u793e\u4f1a\u81f3\u5173\u91cd\u8981\u3002\u6839\u636e\u76ee\u524d\u7684\u4e0d\u5b8c\u6574\u7edf\u8ba1\uff0c\u4e2d\u56fd\u6709\u903e\u4e00\u767e\u5bb6\u4e13\u6ce8\u4e8eRNA\u7597\u6cd5\u7684\u516c\u53f8\uff0c\u7edd\u5927\u591a\u6570\u4e3a\u521d\u521b\u4f01\u4e1a\uff0c\u8bc1\u660eRNA\u9886\u57df\u5df2\u5438\u5f15\u4e86\u4e0d\u5c11\u4f01\u4e1a\u8d44\u6e90\uff0c\u53d1\u5c55\u8d8b\u52bf\u5341\u5206\u84ec\u52c3\u3002\u540c\u65f6\uff0c\u6b63\u56e0\u56fd\u5185RNA\u9886\u57df\u5e7f\u5e03\u65b0\u5174\u529b\u91cf\uff0c\u4e1a\u5185\u5bf9\u4e00\u4e9b\u4ea7\u54c1\u540e\u671f\u7814\u53d1\u7684\u7ecf\u9a8c\u6307\u5bfc\u4e0e\u5206\u4eab\u66f4\u4e3a\u6e34\u6c42\uff0c\u6545\u6211\u4eec\u5e0c\u671b\u53ef\u4ee5\u85c9\u6b64\u673a\u4f1a\u4e0e\u672c\u6b21\u8bba\u575b\u96c6\u7ed3\u7684\u884c\u4e1a\u7fd8\u695a\u3001\u4e13\u5bb6\u53ca\u5b66\u8005\uff0c\u4e00\u540c\u63a2\u8ba8RNAi\u7597\u6cd5\u7814\u53d1\u3001CMC\u53ca\u6218\u7565\u65b9\u9762\u7684\u7ecf\u9a8c\u4e0e\u5b66\u8bc6\u3002" Sirnaomics\u4f5c\u4e3a\u5f00\u53d1\u57fa\u4e8e RNA \u7597\u6cd5\u836f\u7269\u7684\u9886\u519b\u4f01\u4e1a\u4e4b\u4e00\uff0c\u4e0e\u9999\u6e2f\u56fd\u9645\u751f\u7269\u5c55\u534f\u529e\u8bba\u575b\u4ee5\u8ba8\u8bba\u5f00\u53d1\u65b0\u7684\u7597\u6cd5\u5e94\u5bf9\u4e0b\u4e00\u4ee3 RNA \u836f\u7269\u4e8e\u751f\u4ea7\u65b9\u9762\u7684\u6311\u6218\uff0c\u63a2\u7d22\u5c31\u6bcf\u5e74\u5bfc\u81f4\u6570\u767e\u4e07\u4eba\u6b7b\u4ea1\u7684\u75be\u75c5\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\u7684\u53ef\u80fd\u6027\uff0c\u4ece\u800c\u6fc0\u53d1\u751f\u4ea7RNA\u7597\u6cd5\u65b0\u4ea7\u54c1\u7684\u7075\u611f\uff0c\u540c\u65f6\u9884\u9632\u672a\u6765\u5927\u578b\u6d41\u884c\u75be\u75c5\u6216\u5176\u5b83\u536b\u751f\u5371\u673a\u7684\u51b2\u51fb\u3002Sirnaomics\u9996\u5e2d\u5236\u9020\u5b98\u738b\u6c38\u7965\u535a\u58eb\u3001\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u5f00\u53d1\u9ad8\u7ea7\u526f\u603b\u88c1 Francois Lebel\u535a\u58eb\u3001CMC\u526f\u603b\u88c1Richard W. Welch\u535a\u58eb\u3001\u96c6\u56e2\u5b50\u516c\u53f8RNAimmune\u9996\u5e2d\u6267\u884c\u5b98\u517c\u603b\u88c1\u6c88\u680b\u535a\u58eb\u3001\u5065\u65b0\u539f\u529b\u603b\u88c1\u674e\u7389\u73b2\u535a\u58eb\u53ca\u5e7f\u5dde\u9510\u535a\u5236\u836f\u526f\u603b\u88c1\u5f20\u8d85\u6210\u5148\u751f\u5e94\u9080\u51fa\u5e2d\u5e76\u5c31RNAi\u7597\u6cd5\u4e34\u5e8a\u5f00\u53d1\u3001\u751f\u4ea7\u53ca\u5546\u4e1a\u5316\u8fdb\u884c\u5206\u4eab\u3002 \u5176\u4e2d\uff0cSirnaomics\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u5f00\u53d1\u9ad8\u7ea7\u526f\u603b\u88c1 Francois Lebel\u535a\u58eb\u5177\u6709\u903e30\u5e74\u7684\u56fd\u9645\u751f\u7269\u5236\u836f\u5de5\u4f5c\u7ecf\u9a8c\uff0c\u5176\u8d1f\u8d23\u8bbe\u8ba1\u5e76\u7ba1\u7406\u7684\u56fd\u9645\u7814\u53d1\u9879\u76ee\u5df2\u6210\u529f\u83b7\u5f97\u591a\u4e2a\u4ea7\u54c1\u7684\u4e0a\u5e02\u8bb8\u53ef\u3002\u5176\u5c31\u57fa\u4e8e\u591a\u80bd\u7eb3\u7c73\u9897\u7c92\u9012\u9001\u5e73\u53f0\u53caGalNAc\u9012\u9001\u5e73\u53f0\u7684RNAi\u7597\u6cd5\u4ea7\u54c1\u7684\u4e34\u5e8a\u5f00\u53d1\u8fdb\u884c\u5206\u4eab\uff1a"\u7531\u4e8e\u76ee\u524d\u5e02\u9762\u4e0a\u90e8\u5206\u5c0f\u578b\u516c\u53f8\u7684\u7814\u53d1\u66f4\u52a0\u4fa7\u91cd\u4e8e\u67d0\u4e9b\u7279\u5b9a\u75be\u75c5\uff0c\u5176\u672a\u6765\u5546\u4e1a\u5316\u540e\u7684\u5e02\u573a\u6f5c\u529b\u5c06\u53d7\u5230\u5c40\u9650\u3002\u800c\u5f53\u4e0bRNAi\u7597\u6cd5\u4f5c\u4e3a\u84dd\u6d77\u5e02\u573a\uff0c\u552f\u6709\u9769\u65b0\u7684\u9012\u9001\u5e73\u53f0\u6280\u672f\uff0c\u62d3\u5c55\u9002\u5e94\u75c7\u9886\u57df\uff0c\u65b9\u80fd\u8ba9\u516c\u53f8\u53d1\u5c55\u884c\u7a33\u81f4\u8fdc\u3002" \u5728\u5706\u684c\u8ba8\u8bba\u73af\u8282\uff0cSirnaomics\u6267\u884c\u8463\u4e8b\u517c\u9996\u5e2d\u6218\u7565\u5b98\u6234\u6653\u7545\u535a\u58eb\u62c5\u4efb\u4e3b\u6301\uff0c\u5706\u56e0\u751f\u7269\u9996\u5e2d\u5546\u52a1\u5b98\u5434\u654f\u535a\u58eb\u3001\u534e\u6da6\u6b63\u5927\u751f\u547d\u79d1\u5b66\u57fa\u91d1\u8463\u4e8b\u603b\u7ecf\u7406\u67f3\u8fbe\u5148\u751f\u3001Sirnaomics\u5b50\u516c\u53f8EDIRNA\u9996\u5e2d\u6267\u884c\u5b98Christopher Kennedy \u5148\u751f\u4ee5\u53ca\u9999\u6e2f\u5927\u5b66\u8bb2\u5ea7\u6559\u6388\u4e07\u94a7\u535a\u58eb\u7b49\u4e00\u4f17\u5609\u5bbe\uff0c\u4e0e\u89c2\u4f17\u5206\u4eab\u5176\u4e8eRNA\u6295\u8d44\u4e0e\u672a\u6765\u5408\u4f5c\u7684\u4e13\u4e1a\u89c1\u89e3\u3002 Sirnaomics\u521b\u59cb\u4eba\u3001\u6267\u884c\u8463\u4e8b\u3001\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u9646\u9633\u535a\u58eb\u4e8e\u95ed\u5e55\u81f4\u8f9e\u4e2d\u603b\u7ed3\uff1a"\u6211\u4eec\u5728\u672c\u6b21\u8bba\u575b\u4e2d\u900f\u8fc7\u5404\u4e2a\u4e0d\u540c\u7684\u89d2\u5ea6\u5bf9\u5c0f\u6838\u9178\u7597\u6cd5\u8fdb\u884c\u4e86\u6df1\u5ea6\u63a2\u8ba8\uff0c\u7531\u6b64\u6211\u4eec\u786e\u4fe1RNA\u7597\u6cd5\u6b63\u5728\u5f15\u9886\u65b0\u4e00\u8f6e\u7684\u751f\u7269\u79d1\u6280\u6d6a\u6f6e\uff0c\u800c\u9999\u6e2f\u4f5c\u4e3a\u521b\u79d1\u56fd\u9645\u5927\u90fd\u4f1a\u4ea6\u7d27\u8ddf\u6f6e\u6d41\u5e76\u80a9\u800c\u8d77\uff0c\u5229\u7528\u5168\u7403\u82f1\u624d\u805a\u9999\u6c5f\u4e4b\u4f18\u52bf\uff0c\u4e3a\u9999\u6e2f\u79d1\u6280\u8c31\u65b0\u7bc7\u3002" \u6b64\u5916\uff0cSirnaomics\u96c6\u56e2\u9996\u5e2d\u8d22\u52a1\u5b98\u53f6\u6c38\u57fa\u5148\u751f\u4ea6\u53d7\u9080\u53c2\u52a0\u4e8e9\u670815\u65e5\u4e3e\u529e\u7684\u5706\u684c\u8ba8\u8bba"\u5bfb\u627e\u4e0b\u4e00\u4e2a\u751f\u547d\u79d1\u5b66\u72ec\u89d2\u517d"\uff0c\u5171\u540c\u63a2\u8ba8\u65b0\u5174\u751f\u547d\u79d1\u6280\u9886\u57df\u4e2d\u7684\u7ecf\u6d4e\u673a\u9047\u4e0e\u6295\u8d44\u6f5c\u529b\u3002 \u5173\u4e8eBIOHK2023\u9999\u6e2f\u751f\u7269\u79d1\u6280\u534f\u4f1a\uff08HKBIO\uff09\u6210\u7acb\u4e8e2010\u5e74\uff0c\u662f\u4e00\u4e2a\u7531\u77e5\u540d\u7684\u4e1a\u754c\u548c\u5b66\u672f\u754c\u4ee3\u8868\u7ec4\u6210\u7684\u975e\u8425\u5229\u6027\u7ec4\u7ec7\uff0c\u81f4\u529b\u4e8e\u63a8\u52a8\u9999\u6e2f\u6210\u4e3a\u4e9a\u6d32\u7684\u751f\u7269\u6280\u672f\u4e2d\u5fc3\u3002BIOHK2023\uff08\u9999\u6e2f\u56fd\u9645\u751f\u7269\u79d1\u6280\u8bba\u575b\u66a8\u5c55\u89c8\uff09\u662f\u7531HKBIO\u7ec4\u7ec7\u7684\u56fd\u9645\u4f1a\u8bae\uff0c\u4ecb\u7ecd\u6765\u81ea\u5168\u7403\u5404\u5730\u7684\u6700\u5148\u8fdb\u7684\u521b\u65b0\u751f\u7269\u6280\u672f\uff0c\u662f\u4e9a\u6d32\u89c4\u6a21\u6700\u5927\u7684\u751f\u7269\u79d1\u6280\u5927\u4f1a\uff0c\u65e8\u5728\u4ecb\u7ecd\u5168\u7403\u6700\u5148\u8fdb\u7684\u751f\u7269\u79d1\u6280\u521b\u65b0\u6210\u679c\uff0c\u6c47\u805a\u5168\u7403\u751f\u7269\u79d1\u6280\u884c\u4e1a\uff0c\u56e2\u7ed3\u4f01\u4e1a\u5bb6\u3001\u6295\u8d44\u8005\u548c\u884c\u4e1a\u7231\u597d\u8005\uff0c\u521b\u9020\u65e0\u4e0e\u4f26\u6bd4\u7684\u4ea4\u6d41\u673a\u4f1a\u3002 \u5173\u4e8eSirnaomics Ltd. 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