{"id":94267,"date":"2023-09-06T17:45:00","date_gmt":"2023-09-06T10:45:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023090617450094267"},"modified":"2023-09-07T20:14:03","modified_gmt":"2023-09-07T12:14:03","slug":"%e8%85%be%e7%9b%9b%e5%8d%9a%e8%8d%af%e5%ae%a3%e5%b8%83brii-179%ef%bc%88vbi-2601%ef%bc%89%e8%81%94%e5%90%88peg-ifn%ce%b1%e6%b2%bb%e7%96%97%e6%85%a2%e6%80%a7%e4%b9%99%e5%9e%8b%e8%82%9d%e7%82%8e%e7%9a%84","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023090617450094267","title":{"rendered":"\u817e\u76db\u535a\u836f\u5ba3\u5e03BRII-179\uff08VBI-2601\uff09\u8054\u5408PEG-IFN\u03b1\u6cbb\u7597\u6162\u6027\u4e59\u578b\u809d\u708e\u76842\u671f\u7814\u7a76\u671f\u4e2d\u5206\u6790\u9876\u7ebf\u7ed3\u679c"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/Logo-514.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><p><i>BRII-179\uff08VBI-2601\uff09<\/i><i>\u4e0e\u6807\u51c6\u7597\u6cd5<\/i><i>PEG-IFN<\/i><i>\u237a<\/i><i>\u7684\u8054\u5408\u6cbb\u7597\uff0c\u53ef\u63d0\u9ad8<\/i><i>PEG-IFN<\/i><i>\u237a<\/i><i>\u6cbb\u7597\u7ed3\u675f\u548c<\/i><i>12<\/i><i>\u5468\u968f\u8bbf\u65f6\u7684\u4e59\u809d\u8868\u9762\u6297\u539f\uff08<\/i><i>HBsAg<\/i><i>\uff09\u6e05\u9664\u7387<\/i><\/p>\n<p><i>BRII-179\u6cbb\u7597\u4e0e<\/i><i>HBsAg<\/i><i>\u6e05\u9664\u7387\u7684\u589e\u52a0\u76f8\u5173\uff0c\u5e76\u4e0e<\/i><i>HBsAg\u8840\u6e05\u5b66\u8f6c\u6362\u7387\u7684\u663e\u8457\u589e\u52a0\u5bc6\u5207\u76f8\u5173<\/i><\/p>\n<p><i>\u5b89\u5168\u6027\u7ed3\u679c\u4e0e\u6b64\u524d\u62a5\u544a\u7684<\/i><i>PEG-IFN<\/i><i>\u237a<\/i><i>\u548c<\/i><i>BRII-179\u6cbb\u7597\u7684\u5b89\u5168\u6027\u7ed3\u679c<\/i><i>\u76f8\u4f3c<\/i><\/p>\n<p><span class=\"legendSpanClass\">\u4e2d\u56fd\u5317\u4eac\u548c\u7f8e\u56fd\u5317\u5361\u7f57\u83b1\u7eb3\u5dde\u8fbe\u52d2\u59c6\u5e02<\/span><span class=\"legendSpanClass\">2023\u5e749\u67086\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212;&nbsp;<a href=\"https:\/\/www.briibio.com\/cn\/\" target=\"_blank\" rel=\"nofollow noopener\">\u817e\u76db\u535a\u836f\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8<\/a>\uff08&quot;\u817e\u76db\u535a\u836f&quot;\uff0c&quot;\u6211\u4eec&quot;\u6216&quot;\u516c\u53f8&quot;\uff0c\u80a1\u7968\u4ee3\u7801\uff1a2137.HK\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u4e8e\u9488\u5bf9\u60a3\u8005\u672a\u88ab\u6ee1\u8db3\u7684\u9700\u6c42\u4ee5\u53ca\u91cd\u5927\u516c\u5171\u536b\u751f\u6027\u75be\u75c5\u5f00\u53d1\u521b\u65b0\u7597\u6cd5\u7684\u8de8\u56fd\u4f01\u4e1a\uff0c\u4eca\u65e5\u516c\u5e03\u4e86\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u76842\u671f\u7814\u7a76<span id=\"spanHghltb804\">\u6cbb\u7597\u7ec4\u522b\u5c42\u9762\u63ed\u76f2<\/span>\u7684\u7b2c 36 \u5468\u9876\u7ebf\u6570\u636e\u7ed3\u679c\u3002\u8be5\u6570\u636e\u6765\u81eaBRII-179\uff0c\u4e00\u79cd\u9996\u521b\u7684Pre-S1\/Pre-S2\/S\u6cbb\u7597\u6027\u75ab\u82d7\u4e0e\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u237a\uff08PEG-IFN\u237a\uff09\u8054\u5408\u6cbb\u7597\u6162\u6027\u4e59\u578b\u809d\u708e\uff08CHB\uff09\u60a3\u8005\u7684\u671f\u4e2d\u5206\u6790\u3002\u5728\u6b64\u524d\u7684\u7814\u7a76\u4e2d\uff0c\u66fe\u62a5\u544a\u8fc7BRII-179\u80fd\u8bf1\u5bfcCHB\u60a3\u8005\u4ea7\u751f\u9488\u5bf9Pre-S1\u3001Pre-S2 \u548cS\u8868\u4f4d\u7684\u5e7f\u6cdb\u6297\u4f53\u548cT\u7ec6\u80de\u53cd\u5e94\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>\u8be5\u7814\u7a76\u7684<span id=\"spanHghlt5335\">\u6cbb\u7597\u7ec4\u522b\u5c42\u9762\u63ed\u76f2<\/span>\u6570\u636e\u663e\u793a\uff0c\u5728\u7b2c24\u5468\uff08\u6cbb\u7597\u7ed3\u675f\u6216EOT\uff09\u7684\u610f\u5411\u6cbb\u7597\u5206\u6790\u4e2d\uff0c\u670926.3%\uff0815\u4f8b\uff09\u63a5\u53d7BRII-179\/PEG-IFN\u03b1\u6cbb\u7597\u7684\u60a3\u8005\u5b9e\u73b0\u4e86HBsAg\u6e05\u9664\uff0c\u800c\u5728\u63a5\u53d7\u5b89\u6170\u5242\/PEG-IFN\u03b1\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\uff0c\u670919.3%\uff0811\u4f8b\uff09\u5b9e\u73b0\u4e86HBsAg\u6e05\u9664\u3002\u5728\u7b2c 36 \u5468\uff08\u6cbb\u7597\u7ed3\u675f\u540e12 \u5468\u968f\u8bbf\uff09\uff0c\u670924.6%\uff0814\u4f8b\uff09\u63a5\u53d7BRII-179\/PEG-IFN\u03b1 \u6cbb\u7597\u7684\u60a3\u8005\u5b9e\u73b0\u4e86HBsAg\u6e05\u9664\uff0c\u800c\u5728\u63a5\u53d7\u5b89\u6170\u5242\/PEG-IFN\u03b1\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\uff0c 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id=\"spanHghlt01bb\">\u6cbb\u7597\u7ec4\u522b\u5c42\u9762\u63ed\u76f2<\/span>\u5b89\u5168\u6027\u6570\u636e\u663e\u793a\uff0cBRII-179\/PEG-IFN\u03b1\u6cbb\u7597\u603b\u4f53\u4e0a\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e0d\u826f\u4e8b\u4ef6\u4e0ePEG-IFN\u03b1\u6cbb\u7597\u7684\u4e0d\u826f\u53cd\u5e94\u6216\u6b64\u524d\u62a5\u544a\u7684BRII-179\u6cbb\u7597\u7684\u4e0d\u826f\u4e8b\u4ef6\u76f8\u4f3c\u3002\u76ee\u524d\u968f\u8bbf\u6b63\u5728\u8fdb\u884c\u4e2d\u3002<\/p>\n<p>\u817e\u76db\u535a\u836f\u9996\u5e2d\u533b\u5b66\u5b98David Margolis\u535a\u58eb\u8868\u793a\uff1a&quot;BRII-179\u80fd\u8bf1\u5bfc\u529f\u80fd\u6027\u514d\u75ab\u53cd\u5e94\uff0c\u5bf9PEG-IFN\u03b1\u7b49\u5176\u4ed6\u6cbb\u7597\u65b9\u5f0f\u8d77\u5230\u8865\u5145\u4f5c\u7528\uff0c\u8fd9\u9879\u6982\u5ff5\u9a8c\u8bc1\u6027\u7814\u7a76\u7684\u6570\u636e\u4e0e\u6211\u4eec\u4e4b\u524d\u7684\u673a\u5236\u9a8c\u8bc1\u6027\u7814\u7a76\u7ed3\u679c\u4e00\u81f4\uff0c\u6211\u4eec\u5bf9\u6b64\u611f\u5230\u975e\u5e38\u5174\u594b\u3002\u6211\u4eec\u671f\u5f85\u901a\u8fc7\u6b63\u5728\u8fdb\u884c\u4ee5\u53ca\u672a\u6765\u7684\u7814\u7a76\uff0c\u7ee7\u7eed\u8bc4\u4f30\u8fd9\u4e00\u4e00\u6d41\u7684\u514d\u75ab\u6cbb\u7597\u5019\u9009\u836f\u7269\uff0c\u52aa\u529b\u4e3a\u5168\u7403 2.9 \u4ebf \u6162\u6027HBV \u611f\u67d3\u8005\u63d0\u4f9b\u6700\u9ad8\u7684HBV\u529f\u80fd\u6027\u6cbb\u6108\u7387\u3002&quot;<\/p>\n<p>Vir Biotechnology\u8bc4\u4f30 BRII-835\uff08VIR-2218\uff09\u8054\u5408\u6216\u4e0d\u8054\u5408PEG-IFN\u03b1\u7684\u7814\u7a76\uff0c\u4ee5\u53ca\u817e\u76db\u535a\u836f\u6b63\u5728\u8fdb\u884c\u7684BRII-179\u4e0eBRII-835\u8054\u7528\u76842\u671f\u7814\u7a76\u7b49\u591a\u9879\u7814\u7a76\u7684\u79ef\u6781\u7ed3\u679c\uff0c\u5747\u663e\u793a\u6301\u4e45\u7684HBsAg\u6e05\u9664\u4e0e\u6297\u4f53\u53cd\u5e94\u4e4b\u95f4\u5b58\u5728\u663e\u8457\u7684\u76f8\u5173\u6027\uff0c\u51f8\u663e\u4e86BRII-179\u6709\u6f5c\u529b\u4f5c\u4e3aHBV\u529f\u80fd\u6027\u6cbb\u6108\u65b9\u6848\u4e2d\u91cd\u8981\u7684\u514d\u75ab\u8c03\u8282\u836f\u7269\u3002<\/p>\n<p>\u4e0e\u6b64\u540c\u65f6\uff0c\u817e\u76db\u535a\u836f\u65b0\u542f\u52a8\u7684\u4e00\u9879HBV 2\u671f\u7814\u7a76\uff0c\u5c06BRII-835 + PEG-IFN\u03b1\u8054\u7528\u4e0e\u5355\u7528PEG-IFN\u03b1\u7684\u5bf9\u7167\u7ec4\u8fdb\u884c\u4e86\u6bd4\u8f83\uff0c\u65e8\u5728\u660e\u786e\u8054\u5408\u7528\u836f\u5728\u5b9e\u73b0\u529f\u80fd\u6027\u6cbb\u6108\u4e0a\u7684\u989d\u5916\u6548\u679c\u3002\u516c\u53f8\u8ba1\u5212\u5728\u8be52\u671f\u7814\u7a76\u4e2d\u7eb3\u5165\u4e9a\u592a\u5730\u533a\u66fe\u63a5\u53d7\u8fc7BRII-179\u6cbb\u7597\u7684\u60a3\u8005\u3002\u516c\u53f8\u76f8\u4fe1\uff0cBRII-179 \u5177\u6709\u72ec\u7279\u7684\u80fd\u529b\uff0c\u53ef\u4ee5\u8bc6\u522b\u5177\u6709\u826f\u597d\u5185\u5728\u4f53\u6db2\u514d\u75ab\u5e94\u7b54\u7684\u60a3\u8005\u3002<\/p>\n<p>2023\u5e747\u6708\uff0c\u817e\u76db\u535a\u836f\u5c06VBI Vaccines\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aVBIV\uff09\u7684BRII-179\uff08VBI-2601\uff09\u8bb8\u53ef\u6743\u76ca\u6269\u5c55\u81f3\u5168\u7403\u3002\u516c\u53f8\u8ba1\u5212\u5728\u4e0d\u4e45\u7684\u5c06\u6765\u5f00\u5c55\u66f4\u591a\u8054\u5408\u7814\u7a76\uff0c\u4ee5\u63a2\u8ba8BRII-179\uff08VBI-2601\uff09\u63d0\u9ad8\u6297\u4f53\u5e94\u7b54\u7684\u80fd\u529b\uff0c\u5e76\u4e3a\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u7684\u6f5c\u5728\u6cbb\u6108\u6027\u7597\u6cd5\u3002<\/p>\n<p>\u66f4\u591a\u8be6\u7ec6\u6570\u636e\u5c06\u5728\u672a\u6765\u7684\u79d1\u5b66\u4f1a\u8bae\u4e0a\u8fdb\u884c\u5206\u4eab\u3002<\/p>\n<p><b>\u5173\u4e8e<\/b><b>BRII-179 (VBI-2601) + PEG-IFN\u03b1\u8054\u5408\u7597\u6cd5\u7814\u7a76<\/b><\/p>\n<p>\u6b642\u671f\u7814\u7a76\u662f\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u5e73\u884c\u7ec4\u7814\u7a76\uff0c\u65e8\u5728\u8bc4\u4f30\u5728PEG-IFN\u03b1\u548cNrtI\u57fa\u7840\u4e0a\u8054\u5408BRII-179\u6cbb\u7597\u6162\u6027HBV\u611f\u67d3\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u8fd9\u9879\u7814\u7a76\u62db\u52df\u4e86\u4e2d\u56fd\u5927\u9646\u7684\u6210\u5e74\u6162\u6027HBV\u611f\u67d3\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u5df2\u6309\u7167\u6cbb\u7597\u6307\u5357\u63a5\u53d7\u4e8624\u81f328\u5242PEG-IFN\u03b1\uff0c\u4ee5\u53ca\u81f3\u5c11\u63a5\u53d7\u4e8612\u4e2a\u6708\u7684NrtI\u6cbb\u7597\uff0c\u5e76\u7b26\u5408\u9884\u8bbe\u5b9a\u7684\u90e8\u5206\u5e94\u7b54\u6807\u51c6\u3002\u53d7\u8bd5\u8005\u63091:1\u6bd4\u4f8b\u968f\u673a\u63a5\u53d7BRII-179\u6216\u5b89\u6170\u5242\u6cbb\u7597\uff0c\u572818\u5468\u5185\u63a5\u53d7\u6bcf3\u5468\u4e00\u6b21\uff0c\u5171\u8ba17\u6b21\u7ed9\u836f\uff0c\u540c\u65f6\u7ee7\u7eed\u63a5\u53d7PEG-IFN\u03b1\u6cbb\u759724\u5468\u3002\u7b26\u5408Nrtl\u505c\u836f\u6807\u51c6\u7684\u53d7\u8bd5\u8005\u5c06\u505c\u6b62Nrtl\u6cbb\u7597\uff0c\u5e76\u7ee7\u7eed\u63a5\u53d7\u989d\u591648\u5468\u7684\u968f\u8bbf\u3002<\/p>\n<p><b>\u5173\u4e8e\u4e59\u578b\u809d\u708e<\/b><\/p>\n<p>\u4e59\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u662f\u4e16\u754c\u4e0a\u6700\u91cd\u5927\u7684\u611f\u67d3\u6027\u75be\u75c5\u5a01\u80c1\u4e4b\u4e00\uff0c\u5168\u7403\u611f\u67d3\u4eba\u6570\u8d85\u8fc72.9\u4ebf\u3002<sup>[1]<\/sup>\u6162\u6027HBV\u611f\u67d3\u662f\u809d\u810f\u75be\u75c5\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u6bcf\u5e74\u7ea6\u670982\u4e07\u4eba\u6b7b\u4e8e\u6162\u6027HBV\u611f\u67d3\u7684\u5e76\u53d1\u75c7\u3002<sup>[1]<\/sup>\u4e2d\u56fd\u6162\u6027HBV\u611f\u67d3\u4eba\u6570\u8fbe8,700\u4e07\uff0c\u975e\u5e38\u503c\u5f97\u5173\u6ce8\u3002<sup>[2]<\/sup><\/p>\n<p><b>\u5173\u4e8e<\/b><b>BRII-179\uff08VBI-2601\uff09<\/b><\/p>\n<p>BRII-179\uff08VBI-2601\uff09\u662f\u4e00\u79cd\u57fa\u4e8e\u91cd\u7ec4\u86cb\u767d\u8d28\u7684\u65b0\u578bHBV \u514d\u75ab\u6cbb\u7597\u5019\u9009\u836f\u7269\uff0c\u53ef\u8868\u8fbePre-S1 \u3001 Pre-S2 \u548c S HBV \u8868\u9762\u6297\u539f\uff0c\u65e8\u5728\u8bf1\u5bfc\u589e\u5f3a\u548c\u5e7f\u6cdb\u7684B \u7ec6\u80de\u548c T \u7ec6\u80de\u514d\u75ab\u5e94\u7b54\u3002\u4f5c\u4e3a\u6cbb\u7597\u6162\u6027HBV\u611f\u67d3\u7684\u6f5c\u5728\u529f\u80fd\u6027\u6cbb\u6108\u65b9\u6848\u7684\u4e00\u90e8\u5206\uff0c\u817e\u76db\u535a\u836f\u6b63\u5728\u5f00\u5c55BRII-179\u4e0eBRII-835\uff08VIR-2218\uff09\u8054\u5408\u7528\u836f\uff0c\u53caBRII-179\u4e0ePEG-IFN\u03b1\u8054\u5408\u7528\u836f\u7684\u4e24\u98792\u671f\u7814\u7a76\u3002<\/p>\n<p><b><u>\u5173\u4e8e\u817e\u76db\u535a\u836f<\/u><\/b><\/p>\n<p>\u817e\u76db\u535a\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a2137.HK\uff09\u662f\u4e00\u5bb6\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u9488\u5bf9\u5b58\u5728\u5de8\u5927\u672a\u88ab\u6ee1\u8db3\u7684\u60a3\u8005\u9700\u6c42\u3001\u6cbb\u7597\u624b\u6bb5\u6709\u9650\uff0c\u4ee5\u53ca\u7ed9\u60a3\u8005\u5e26\u6765\u4e25\u91cd\u793e\u4f1a\u6b67\u89c6\u7684\u91cd\u5927\u516c\u5171\u536b\u751f\u6311\u6218\u5f00\u53d1\u521b\u65b0\u7597\u6cd5\u3002\u516c\u53f8\u4e13\u6ce8\u4e8e\u4f20\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff0c\u6b63\u5728\u63a8\u8fdb\u4e00\u6761\u6db5\u76d6\u591a\u79cd\u72ec\u7279\u5019\u9009\u836f\u7269\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5e76\u901a\u8fc7\u9886\u5148\u7684\u9879\u76ee\u5f00\u53d1\u9488\u5bf9\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u65b0\u578b\u529f\u80fd\u6027\u6cbb\u6108\u65b9\u6848\uff0c\u548c\u9488\u5bf9\u4ea7\u540e\u6291\u90c1\u75c7\uff08PPD\uff09\u4ee5\u53ca\u91cd\u5ea6\u6291\u90c1\u75c7\uff08MDD\uff09\u7684\u9996\u521b\u6cbb\u7597\u65b9\u6848\u3002\u5728\u5bcc\u6709\u8fdc\u89c1\u5353\u8bc6\u548c\u7ecf\u9a8c\u4e30\u5bcc\u7684\u9886\u5bfc\u56e2\u961f\u5e26\u9886\u4e0b\uff0c\u516c\u53f8\u5728\u4f4d\u4e8e\u7f57\u5229-\u8fbe\u52d2\u59c6\u3001\u65e7\u91d1\u5c71\u6e7e\u533a\u3001\u5317\u4eac\u548c\u4e0a\u6d77\u7684\u4e3b\u8981\u751f\u7269\u6280\u672f\u4e2d\u5fc3\u5f00\u5c55\u4e1a\u52a1\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee<a href=\"http:\/\/www.briibio.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.briibio.com<\/a>\u3002<\/p>\n[1] World Health Organization. (<span class=\"xn-chron\">June 2022<\/span>). <i>Hepatitis B.<\/i> World Health Organization. Retrieved from <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b<\/a>&nbsp;<\/p>\n[2] World Health Organization. <i>Hepatitis.<\/i> World Health Organization. Retrieved from <a href=\"https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C<\/a>.<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder2\">  <\/div>\n","protected":false},"excerpt":{"rendered":"<p>BRII-179\uff08VBI-2601\uff09\u4e0e\u6807\u51c6\u7597\u6cd5PEG-IFN\u237a\u7684\u8054\u5408\u6cbb\u7597\uff0c\u53ef\u63d0\u9ad8PEG-IFN\u237a\u6cbb\u7597\u7ed3\u675f\u548c12\u5468\u968f\u8bbf\u65f6\u7684\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6e05\u9664\u7387 BRII-179\u6cbb\u7597\u4e0eHBsAg\u6e05\u9664\u7387\u7684\u589e\u52a0\u76f8\u5173\uff0c\u5e76\u4e0eHBsAg\u8840\u6e05\u5b66\u8f6c\u6362\u7387\u7684\u663e\u8457\u589e\u52a0\u5bc6\u5207\u76f8\u5173 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[1] World&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2023090617450094267\">Read 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