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\u6b64\u6b21\u6269\u5c55\u9002\u5e94\u75c7\u7684\u83b7\u6279\u662f\u57fa\u4e8emonarchE\u7814\u7a76\u76844\u5e74\u6570\u636e\u3002monarchE\u7814\u7a76\u662f\u4e00\u9879\u5168\u7403\u968f\u673a\u591a\u4e2d\u5fc3III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u5171\u572838\u4e2a\u56fd\u5bb6603\u4e2a\u4e2d\u5fc3\u5165\u7ec4\u4e865637\u4f8b\u60a3\u8005\uff0c\u5176\u4e2d\u5305\u62ec501\u4f8b\u4e2d\u56fd\u60a3\u8005[4]<\/sup>\uff0c\u65e8\u5728\u9a8c\u8bc1\u552f\u62e9®<\/sup>\uff08\u963f\u8d1d\u897f\u5229\u7247\uff09\u8054\u5408\u5185\u5206\u6ccc\u6cbb\u7597\u76f8\u8f83\u5355\u72ec\u5185\u5206\u6ccc\u6cbb\u7597\u5bf9\u4e8eHR+, HER2-\u9ad8\u5371\u65e9\u671f\u4e73\u817a\u764c\u60a3\u8005\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002monarchE\u7814\u7a76\u6700\u65b0\u7ed3\u679c\u663e\u793a\uff0c\u65e9\u671f\u4e73\u817a\u764c\u9ad8\u5371\u60a3\u8005\u672f\u540e\u63a5\u53d7\u5185\u5206\u6ccc\u6cbb\u7597\u8054\u5408\u552f\u62e9®<\/sup>\uff08\u963f\u8d1d\u897f\u5229\u7247\uff092\u5e74\uff0c\u4e0e\u5355\u72ec\u5185\u5206\u6ccc\u6cbb\u7597\u76f8\u6bd4\uff0c\u5728\u65e0\u6d78\u6da6\u6027\u75be\u75c5\u751f\u5b58\uff08IDFS\uff09\u548c\u65e0\u8fdc\u5904\u590d\u53d1\u751f\u5b58\uff08DRFS\uff09\u65b9\u9762\u8868\u73b0\u51fa\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u7684\u663e\u8457\u6539\u5584\u548c\u6301\u7eed\u83b7\u76ca[5]<\/sup>\u3002\u5728\u4e2d\u56fd\u65e9\u671f\u4e73\u817a\u764c\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u7684\u963f\u8d1d\u897f\u5229\u7597\u6548\u548c\u5b89\u5168\u6027\u7279\u5f81\u4e0e\u5728\u5168\u7403\u4eba\u7fa4\u4e00\u81f4\uff0c\u4e14\u5b89\u5168\u8c31\u4e0e\u5728\u4e2d\u56fd\u665a\u671f\u4e73\u817a\u764c\u4e34\u5e8a\u7814\u7a76\u4e2d\u6240\u89c2\u5bdf\u5230\u7684\u4e00\u81f4[6],[7]<\/sup>\u3002<\/p>\n

\u793c\u6765\u4e2d\u56fd\u603b\u88c1\u517c\u603b\u7ecf\u7406\u8d1d\u680e\u94ed\u5148\u751f<\/b>\u8868\u793a\uff1a"\u975e\u5e38\u9ad8\u5174\u770b\u5230\u552f\u62e9®<\/sup>\uff08\u963f\u8d1d\u897f\u5229\u7247\uff09\u6269\u5c55\u9002\u5e94\u75c7\u5728\u4e2d\u56fd\u83b7\u6279\u3002\u5728\u4e2d\u56fd\u4e0a\u5e02\u4e24\u5e74\u591a\uff0c\u552f\u62e9®<\/sup>\uff08\u963f\u8d1d\u897f\u5229\u7247\uff09\u5df2\u7ecf\u60e0\u53ca\u8d85\u8fc7\u6570\u4e07\u7684\u4e2d\u56fd\u4e73\u817a\u764c\u7fa4\u4f53\u3002\u76ee\u524d\uff0c\u552f\u62e9®<\/sup>\uff08\u963f\u8d1d\u897f\u5229\u7247\uff09\u5df2\u7ecf\u6210\u4e3a\u60e0\u53ca\u6700\u591a\u4e2d\u56fd\u4e73\u817a\u764c\u7fa4\u4f53\u7684CDK4 & 6\u6291\u5236\u5242[8]<\/sup>\u3002\u6b64\u6b21\u6269\u5c55\u9002\u5e94\u75c7\u7684\u83b7\u6279\uff0c\u5c06\u9020\u798f\u66f4\u591a\u4e2d\u56fd\u9ad8\u5371\u65e9\u671f\u4e73\u817a\u764c\u7fa4\u4f53\uff0c\u52a9\u529b\u964d\u4f4e\u590d\u53d1\u98ce\u9669\uff0c\u5e2e\u52a9\u5979\u4eec\u91cd\u62fe\u7f8e\u597d\u751f\u6d3b\u7684\u5e0c\u671b\u3002\u80bf\u7624\u662f\u793c\u6765\u7684\u6838\u5fc3\u6cbb\u7597\u9886\u57df\u4e4b\u4e00\uff0c\u4f5c\u4e3a\u5168\u7403\u533b\u7597\u5065\u5eb7\u884c\u4e1a\u7684\u9886\u5bfc\u8005\uff0c\u793c\u6765\u4e5f\u5c06\u7ee7\u7eed\u5728\u80bf\u7624\u9886\u57df\u5f00\u7586\u62d3\u571f\uff0c\u52a0\u901f\u521b\u65b0\u836f\u7269\u7684\u5f15\u8fdb\u5e76\u79ef\u6781\u63a8\u52a8\u521b\u65b0\u836f\u7269\u53ef\u53ca\uff0c\u4ee5\u6ee1\u8db3\u4e2d\u56fd\u767e\u59d3\u7684\u533b\u7597\u9700\u6c42\uff0c\u52a9\u529b\u2018\u5065\u5eb7\u4e2d\u56fd2030’\u613f\u666f\u3002"<\/p>\n

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\n\n\n\n\n\n\n\n\n\n\n
\n

[1] <\/sup>Stephen R D Johnston et al. Lancet Oncol. 2023 Jan;24(1):77-90.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[2]<\/sup> Sheffield KM, et al. Future Oncol 2022; 18(21):2667-2682.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[3]<\/sup> Verzenio. Prescribing information. Lilly USA, LLC.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[4]<\/sup> Rastogi P. Presented at: SABCS 2020. Abstract GS1-01.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[5]<\/sup> Johnston SRD, et al.Lancet Oncol.2023;24(1):77-90<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[6] <\/sup>Zhimin Shao, et al.2023 ESMO BC abstract 107P<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[7]<\/sup> Zhang QY, et al.Ther Adv Med Oncol.2020;12:1758835920963925<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[8]<\/sup> IQVIA CHPA National Brand Report, 2023 M06<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n","protected":false},"excerpt":{"rendered":"

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[1] Stephen R D Johnston et al. Lancet Oncol. 2023 Jan;24(1):77-90. [2] Sheffield KM, et al. Future Oncol 2022; 18(21):2667-2682. [3] Verzenio. Prescribing information. Lilly USA, LLC. [4] Rastogi P. Presented at: SABCS 2020. Abstract GS1-01. [5] Johnston SRD, et al.Lancet Oncol.2023;24(1):77-90 [6] Zhimin Shao, et… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-93776","post","type-post","status-publish","format-standard","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/93776","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=93776"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/93776\/revisions"}],"predecessor-version":[{"id":93777,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/93776\/revisions\/93777"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=93776"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=93776"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=93776"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}