{"id":93396,"date":"2023-08-31T09:24:00","date_gmt":"2023-08-31T02:24:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023083109240093396"},"modified":"2023-08-31T21:25:26","modified_gmt":"2023-08-31T13:25:26","slug":"sirnaomics%e5%85%ac%e5%b8%832023%e5%b9%b4%e4%b8%ad%e6%9c%9f%e4%b8%9a%e7%bb%a9","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023083109240093396","title":{"rendered":"Sirnaomics\u516c\u5e032023\u5e74\u4e2d\u671f\u4e1a\u7ee9"},"content":{"rendered":"<p><p><b>\u79ef\u6781\u7684\u4e34\u5e8a\u6570\u636e\u5370\u8bc1\u4e13\u6709\u9012\u9001\u5e73\u53f0\u6f5c\u529b<\/b>&nbsp;<b>\u5de9\u56fa\u4e8e<\/b><b>RNAi<\/b><b>\u7597\u6cd5\u9886\u57df\u7684\u5168\u7403\u9886\u5148\u5730\u4f4d<\/b><\/p>\n<p><b><u>\u4e1a\u52a1\u4eae\u70b9<\/u><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u4e34\u5e8a\u5f00\u53d1\u8fdb\u5c55\u7406\u60f3<\/b><\/li>\n<ul type=\"disc\">\n<li>\u4e0e\u7f8e\u56fdFDA\u7b2cII\u9636\u6bb5\u7ed3\u675f\u4f1a\u8bae\u5e76\u83b7\u5f97\u5176\u6307\u5bfc\u540e\uff0c\u96c6\u56e2\u6b63\u63a8\u8fdb<b>STP705<\/b><b>\u6cbb\u7597<\/b><b>isSCC<\/b>\u7684\u540e\u671f\u4e34\u5e8a\u5f00\u53d1\uff0c\u8fd9\u662f\u4e00\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\uff0c\u5de9\u56fa\u4e86\u96c6\u56e2\u4e8e\u5168\u7403\u764c\u75c7\u6cbb\u7597RNAi\u7597\u6cd5\u9886\u57df\u7684\u9886\u5bfc\u5730\u4f4d\u3002<\/li>\n<li>\u51ed\u501f<b>STP707<\/b>\u79ef\u6781\u7684\u4e2d\u671f\u6570\u636e\uff0c\u96c6\u56e2\u6b63\u79ef\u6781\u63a2\u7d22II\u671f\u8054\u5408\u8bd5\u9a8c\u7684\u5408\u4f5c\uff0c\u4ee5\u7814\u7a76\u5c06STP707\u4e0e\u65b0\u578b\u83b7\u6279\u51c6\u7684\u764c\u75c7\u7597\u6cd5\u76f8\u7ed3\u5408\u7684\u6f5c\u529b\u3002<\/li>\n<li>\u96c6\u56e2\u9996\u4e2aGalAhead&#x2122;\u4ea7\u54c1<b>STP122G<\/b>\u5df2\u83b7\u5f97\u7f8e\u56fdFDA\u7684\u76d1\u7ba1\u8bb8\u53ef\u5f00\u59cbI\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/li>\n<li>\u96c6\u56e2\u7684\u9644\u5c5e\u516c\u53f8RNAimmune, Inc.\u5df2\u83b7\u7f8e\u56fdFDA\u7684\u76d1\u7ba1\u8bb8\u53ef\u5f00\u59cb\u65b0\u51a0\u75c5\u6bd2\uff08SARS-CoV-2\uff09\u5019\u9009\u52a0\u5f3a\u75ab\u82d7<b>RV-1730<\/b>\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/li>\n<\/ul>\n<li><b>\u4ea7\u80fd\u63d0\u5347<\/b><\/li>\n<ul type=\"disc\">\n<li>\u4e8e2023\u5e74\u7b2c\u4e00\u5b63\u5ea6\u751f\u4ea7\u7528\u4e8e\u4eba\u4f53\u6ce8\u5c04\u7684STP707\u7684\u5b8c\u6574GMP\u6279\u6b21\u540e\uff0c\u5e7f\u5dde\u5de5\u5382\u9884\u671f\u53ef\u5168\u9762\u6309\u7167GMP\u89c4\u8303\u751f\u4ea7Sirnaomics\u7684\u7ba1\u7ebf\u4ea7\u54c1\u3002\u96c6\u56e2\u4ea6\u542f\u52a8\u704c\u88c5\u7ebf\u7684\u4ea7\u80fd\u63d0\u5347\uff0c\u5305\u62ec2R\u74f6\u6db2\u4f53\u5242\u91cf\u704c\u88c5\uff0c\u4ee5\u652f\u6301GalAhead&#x2122;\u5e73\u53f0\u3002<\/li>\n<\/ul>\n<li><b>\u83b7\u9999\u6e2f\u79d1\u6280\u56ed\u8ba4\u53ef<\/b><\/li>\n<ul type=\"disc\">\n<li>Sirnaomics\u83b7\u5f97\u9999\u6e2f\u79d1\u6280\u56ed\u4e34\u5e8a\u8f6c\u5316\u4fc3\u6210\u8ba1\u52128\u767e\u4e07\u6e2f\u5143\u53ca\u9999\u6e2f\u79d1\u6280\u56ed\u533b\u7597\u79d1\u6280\u5171\u521b\u5e73\u53f02\u767e\u4e07\u6e2f\u5143\u7684\u8d44\u52a9\u3002<\/li>\n<\/ul>\n<\/ul>\n<p><span class=\"legendSpanClass\">\u9999\u6e2f\u3001\u9a6c\u91cc\u5170\u5dde\u5fb7\u56fd\u57ce\u548c\u4e2d\u56fd\u82cf\u5dde<\/span><span class=\"legendSpanClass\">2023\u5e748\u670831\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; <b>Sirnaomics Ltd.<\/b>\uff08<span id=\"spanHghlt3ba2\">\u201c<\/span>\u516c\u53f8<span id=\"spanHghlt9c5c\">\u201d<\/span>\uff0c\u8fde\u540c\u5176\u9644\u5c5e\u516c\u53f8\uff0c\u7edf\u79f0<span id=\"spanHghlt76e2\">\u201c<\/span>Sirnaomics<span id=\"spanHghltfd50\">\u201d<\/span>\u6216<span id=\"spanHghlt7064\">\u201c<\/span>\u96c6\u56e2<span id=\"spanHghlt512e\">\u201d<\/span>\uff1b\u80a1\u4efd\u4ee3\u53f7\uff1a2257\uff09\uff0c\u4e00\u5bb6\u884c\u4e1a\u9886\u5148\u7684\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1RNAi\u7597\u6cd5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u516c\u5e03\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\uff08<span id=\"spanHghltb9be\">\u201c<\/span>\u671f\u5185<span id=\"spanHghltbc72\">\u201d<\/span>\uff09\u7684\u4e2d\u671f\u4e1a\u7ee9\u3002<\/p>\n<p>2023\u5e74\u4e0a\u534a\u5e74\uff0cSirnaomics\u7684\u7ba1\u7ebf\u53ca\u4e1a\u52a1\u53d1\u5c55\u5747\u53d6\u5f97\u91cd\u5927\u8fdb\u5c55\u3002\u9274\u4e8e\u5168\u7403\u5b8f\u89c2\u7ecf\u6d4e\u7684\u4e0d\u786e\u5b9a\u6027\uff0c\u4e3a\u786e\u4fdd\u6709\u5145\u8db3\u7684\u73b0\u91d1\u50a8\u5907\uff0c\u96c6\u56e2\u5df2\u4f18\u5148\u5c06\u8d44\u6e90\u5206\u914d\u81f3\u6f5c\u529b\u5de8\u5927\u7684\u9879\u76ee\uff0c\u5e76\u4f18\u5316\u5185\u90e8\u7ed3\u6784\uff0c\u4ee5\u5de9\u56fa\u4e13\u95e8\u4ece\u4e8bRNAi\u7597\u6cd5\u7684\u56fd\u9645\u56e2\u961f\uff0c\u91cd\u70b9\u5173\u6ce8\u7f8e\u56fd\u53ca\u4e9a\u6d32\u5e02\u573a\u3002\u51ed\u501f\u4e8eRNA\u7597\u6cd5\u7684\u5e7f\u6cdb\u4e13\u4e1a\u77e5\u8bc6\u53ca\u521b\u65b0\u7684\u9012\u9001\u5e73\u53f0\u6280\u672f\uff0c\u96c6\u56e2\u6709\u6548\u63a8\u884c\u4e34\u5e8a\u53d1\u5c55\u7b56\u7565\uff0c\u4e3a\u5176\u9886\u5148\u4e34\u5e8a\u5019\u9009\u836f\u7269STP705\u3001STP707\u53caSTP122G\u4e8e\u7f8e\u56fd\u542f\u52a8\u4e34\u5e8a\u8bd5\u9a8c\u5960\u5b9a\u57fa\u7840\u3002<\/p>\n<p>\u96c6\u56e2\u4e8e\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u671f\u95f4\u7684\u4e8f\u635f\u4ece46.1\u767e\u4e07\u7f8e\u5143\u6536\u7a84\u81f3\u768441.1\u767e\u4e07\u7f8e\u5143\uff0c\u51cf\u5c11\u4e3b\u8981\u7531\u4e8e\u7814\u53d1\u5f00\u652f\u51cf\u5c11\uff1b\u53ca\u6309\u516c\u5e73\u503c\u8ba1\u5165\u635f\u76ca\u7684\u91d1\u878d\u8d1f\u503a\u7684\u516c\u5e73\u503c\u53d8\u52a8\u4e8f\u635f\u51cf\u5c11\u6240\u62b5\u9500\u3002\u4e8e2023\u5e746\u670830\u65e5\uff0c\u96c6\u56e2\u7684\u8d22\u653f\u7a33\u5065\uff0c\u73b0\u91d1\u53ca\u73b0\u91d1\u7b49\u4ef7\u7269\u3001\u94f6\u884c\u5b9a\u671f\u5b58\u6b3e\u548c\u6295\u8d44\u4ea7\u54c1\u4e3a77.3\u767e\u4e07\u7f8e\u5143\u3002<\/p>\n<p><b><u>\u4e3b\u8981\u5019\u9009\u4ea7\u54c1\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6210\u679c\u559c\u4eba\uff0c\u52a9\u529b\u63a8\u52a8\u5546\u4e1a\u5316\u8fdb\u7a0b<\/u><\/b><\/p>\n<p>Sirnaomics\u4e00\u76f4\u63a8\u8fdbRNA\u521b\u65b0\u7597\u6cd5\u7684\u4f18\u9009\u836f\u7269\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u4ee5\u6539\u5584\u5168\u7403\u60a3\u8005\u7684\u751f\u6d3b\u53ca\u798f\u7949\u3002\u4ee5\u4e0b\u91cc\u7a0b\u7891\u53ca\u6210\u5c31\u4f53\u73b0\u96c6\u56e2\u5728\u6574\u4e2a\u7ba1\u7ebf\u4e2d\u7684\u6301\u7eed\u4e34\u5e8a\u8868\u73b0\u3002<\/p>\n<p>STP705<\/p>\n<p>Sirnaomics\u5df2\u5229\u7528STP705\u7684\u4eba\u4f53\u6982\u5ff5\u9a8c\u8bc1\u6570\u636e\u6269\u5c55\u5176\u4e34\u5e8a\u8bd5\u9a8c\u8303\u56f4\u3002STP705\u7684\u6570\u636e\u5df2\u8868\u660e\u5176\u6cbb\u7597\u539f\u4f4d\u9cde\u72b6\u7ec6\u80de\u764c\uff08isSCC\uff09\u7684\u6709\u6548\u6027\uff0c\u96c6\u56e2\u4ea6\u8fdb\u800c\u63a2\u7d22\u5176\u4e8e\u66f4\u5e7f\u6cdb\u7684\u80bf\u7624\u9002\u5e94\u75c7\u4e2d\u7684\u5e94\u7528\uff0c\u5305\u62ec\u57fa\u5e95\u7ec6\u80de\u764c\uff08BCC\uff09\u3001\u809d\u764c\u53ca\u8102\u80aa\u91cd\u5851\u7b49\u533b\u5b66\u7f8e\u5bb9\u9002\u5e94\u75c7\u3002\u4e8e2023\u5e74\u5e74\u521d\u4e0e\u7f8e\u56fdFDA\u7684\u8ba8\u8bba\u540e\uff0c\u57fa\u4e8e\u79ef\u6781\u7684IIa\u671f\u53caIIb\u671f\u4e34\u5e8a\u6570\u636e\uff0c\u96c6\u56e2\u5df2\u51c6\u5907\u5f00\u5c55\u5176\u7528\u4e8e\u6cbb\u7597isSCC\u7684\u9a8c\u8bc1\u6027\u4e34\u5e8a\u7814\u7a76\u3002\u96c6\u56e2\u4ea6\u8ba1\u5212\u63a8\u8fdb\u4e00\u9879\u5355\u5242\u91cf\u7814\u7a76\uff0c\u4f5c\u4e3a\u4e00\u9879\u5927\u578bIII\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u6807\u7684\u5206\u7ec4\u3002\u6b64\u5916\uff0c\u4ee5STP705\u6cbb\u7597BCC II\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u6700\u7ec8\u6570\u636e\u9884\u8ba1\u5c06\u4e8e2023\u5e74\u4e0b\u534a\u5e74\u516c\u5e03\u3002\u96c6\u56e2\u9884\u671f\u4e8e2023\u5e74\u5e74\u5e95\u63a8\u8fdbSTP705\u76ae\u80a4\u764c\u7684\u7279\u8bb8\u7ecf\u8425\u81f3\u540e\u671f\u5f00\u53d1\u3002\u4e3a\u652f\u6301\u6b64\u7b49\u9879\u76ee\u5e76\u63a8\u8fdb\u4e34\u5e8a\u5f00\u53d1\uff0cSirnaomics\u5728\u7f8e\u56fd\u53ca\u4e9a\u6d32\u7684\u4e34\u5e8a\u56e2\u961f\u900f\u8fc7\u5168\u7403\u5404\u5730\u9488\u5bf9\u4e0d\u540c\u9002\u5e94\u75c7\u7684\u53d7\u8bd5\u7fa4\u4f53\uff0c\u5bf9isSCC\u53ca\u809d\u764c\u7b49\u9002\u5e94\u75c7\u8fdb\u884c\u591a\u4e2d\u5fc3\u7684\u5168\u7403\u8bd5\u9a8c\uff0c\u4ee5\u6536\u96c6\u5168\u9762\u800c\u591a\u6837\u7684\u6570\u636e\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u4e8e2023\u5e746\u6708\uff0c\u96c6\u56e2\u516c\u5e03\u4e86\u6709\u5173\u7814\u7a76\u8179\u90e8\u6574\u5f62\u672f\u60a3\u8005\u8102\u80aa\u91cd\u5851\u7684\u6982\u5ff5\u9a8c\u8bc1\u5f0fI\u671fSTP705\u8bd5\u9a8c\u7684\u4e2d\u671f\u6570\u636e\u3002\u6b64\u6b21\u5ba1\u67e5\u4f7f\u7528\u4e86\u4e0d\u540c\u5242\u91cfSTP705\uff0c\u6240\u6709\u7ec4\u7ec7\u6837\u672c\u5747\u663e\u793a\u51fa\u8102\u80aa\u91cd\u5851\u7684\u7ec4\u7ec7\u5b66\u8bc1\u636e\u3002\u96c6\u56e2\u8ba1\u5212\u5c06\u8be5\u9879\u7814\u7a76\u7684\u8d44\u6599\u7528\u4e8e\u988f\u4e0b\u8102\u80aa\u7684\u6cbb\u7597\u53ca\u975e\u4fb5\u5165\u6027\u8102\u80aa\u91cd\u5851\u7684\u5176\u4ed6\u9886\u57df\u3002\u6b64\u7814\u53d1\u9879\u76ee\u9884\u671f\u4e3a\u96c6\u56e2\u7684\u4ea7\u54c1\u7f10\u5f00\u8f9f\u4e00\u4e2a\u5d2d\u65b0\u7684\u533b\u5b66\u7f8e\u5bb9\u6cbb\u7597\u9886\u57df\uff0c\u5e76\u83b7\u5f97\u826f\u597d\u7684\u5e02\u573a\u53cd\u5e94\u3002<\/p>\n<p>STP707<\/p>\n<p>\u96c6\u56e2\u6b63\u79ef\u6781\u63a8\u8fdbSTP707\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u5168\u8eab\u7ed9\u836f\u7684\u65b9\u5f0f\u6269\u5927\u6cbb\u7597\u8303\u56f4\uff0c\u4e3a\u6cbb\u7597STP705\u65e0\u6cd5\u89e3\u51b3\u7684\u5176\u4ed6\u9002\u5e94\u75c7\u63d0\u4f9b\u4e86\u66f4\u591a\u673a\u4f1a\u3002STP707\u5370\u8bc1\u4e86\u96c6\u56e2\u4e13\u6709\u7684PNP\u9012\u9001\u5e73\u53f0\u4e8e\u9759\u8109\u6ce8\u5c04\u4e2d\u7684\u5b89\u5168\u6027\u53ca\u6709\u6548\u6027\u3002\u57fa\u4e8eSTP707\u79ef\u6781\u7684\u4e2d\u671f\u6570\u636e\uff0c\u96c6\u56e2\u8ba1\u5212\u63a2\u7d22II\u671f\u8054\u5408\u8bd5\u9a8c\u7684\u5408\u4f5c\uff0c\u5c06STP707\u4e0e\u65b0\u578b\u83b7\u6279\u51c6\u7684\u764c\u75c7\u7597\u6cd5\uff08\u5982\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff09\u4ee5\u53ca\u4f20\u7edf\u5316\u7597\u76f8\u7ed3\u5408\u3002\u6709\u5173\u6f5c\u5728\u8054\u5408\u7597\u6cd5\u53ef\u80fd\u5305\u62ec\u80c6\u7ba1\u764c\uff08CCA\uff09\u3001\u809d\u7ec6\u80de\u764c\uff08HCC\uff09\u3001\u9ed1\u8272\u7d20\u7624\u6216\u80f0\u817a\u764c\u3002\u96c6\u56e2\u4ea6\u5c06\u63a2\u7d22II\u671f\u8bd5\u9a8c\u7684\u5176\u4ed6\u9002\u5e94\u75c7\u53ca\u7ee7\u7eed\u6269\u5927\u96c6\u56e2\u7684\u4e34\u5e8a\u5f00\u53d1\u8ba1\u5212\u3002\u9274\u4e8eSTP707\u900f\u8fc7\u9759\u8109\u6ce8\u5c04\u53ca\u6f5c\u5728\u5408\u4f5c\u673a\u4f1a\u6240\u5177\u6709\u7684\u5e9e\u5927\u5e02\u573a\u6f5c\u529b\uff0c\u96c6\u56e2\u76f8\u4fe1\u5c06\u8d44\u672c\u53ca\u4f01\u4e1a\u8d44\u6e90\u7528\u4e8e\u63a8\u8fdb\u6b64\u7b49\u5b9d\u8d35\u8d44\u4ea7\u4e43\u662f\u5176\u6700\u4f73\u53d1\u5c55\u6218\u7565\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u96c6\u56e2\u65e5\u524d\u516c\u544a\u8868\u660eSTP707\u7528\u4ee5\u6cbb\u7597\u591a\u79cd\u5b9e\u4f53\u7624\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c50\u540d\u53d7\u8bd5\u8005\u5747\u4e3a\u60a3\u6709\u5404\u7c7b\u665a\u671f\u5b9e\u4f53\u7624\u4e14\u5bf9\u6807\u51c6\u7597\u6cd5\u65e0\u53cd\u5e94\u3002\u7ea674%\u7684\u53ef\u8bc4\u4f30\u60a3\u8005\u5448\u73b0\u51fa\u75be\u75c5\u7a33\uff08SD\uff09\u7684\u6700\u4f73\u53cd\u5e94\uff0c\u6709\u6570\u540d\u60a3\u8005\u7684\u80bf\u7624\u8d1f\u8377\u91cf\u51cf\u8f7b\u3002<\/p>\n<p><b><u>\u52a0\u901f\u63a8\u8fdb\u66f4\u591a\u7a81\u7834\u6027\u4e00\u6d41\u4e34\u5e8a\u524d\u8d44\u4ea7\u8fdb\u5165\u4e34\u5e8a\u9636\u6bb5<\/u><\/b><\/p>\n<p>\u671f\u5185\uff0c\u96c6\u56e2\u5c06GalAhead&#x2122;\u9012\u9001\u5e73\u53f0\u9996\u4e2a\u4ee3\u8868\u6027\u5019\u9009\u836f\u7269STP122G\u63a8\u8fdb\u81f3\u4e34\u5e8a\u9636\u6bb5\uff0c\u8fd9\u6807\u5fd7\u7740Sirnaomics\u9996\u6b21\u5c06\u5176\u4e13\u6709\u7684GalNAc RNAi\u5e73\u53f0\u6280\u672fGalAhead&#x2122;\u5e94\u7528\u4e8esiRNA\u5019\u9009\u836f\u7269\u4e2d\uff0c\u5e76\u542f\u52a8\u4e86\u4e00\u9879\u8bd5\u9a8c\uff0c\u4ee5\u6ee1\u8db3\u6297\u51dd\u75be\u75c5\u6cbb\u7597\u60a3\u8005\u672a\u88ab\u6ee1\u8db3\u7684\u9700\u6c42\u3002I\u671f\u4e34\u5e8a\u7814\u7a76\u5df2\u4e8e4\u6708\u5c55\u5f00\uff0c\u5e76\u4e8e6\u6708\u5bf9\u7b2c\u4e00\u4f4d\u6297\u51dd\u6cbb\u7597\u53c2\u4e0e\u8005\u8fdb\u884c\u7ed9\u836f\uff0c\u4ee5\u8bc4\u4f30STP122G\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u836f\u52a8\u53ca\u836f\u6548\u3002<\/p>\n<p>\u96c6\u56e2\u8ba1\u5212\u52a0\u5feb\u65b0\u4e00\u4ee3GalAhead&#x2122;\u5e73\u53f0\u7684\u7814\u53d1\uff0c\u5f3a\u5927\u7684\u4ea7\u54c1\u7ba1\u7ebf\u5305\u62ec\u4e5d\u79cdGalAhead&#x2122;\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269\u3002\u4e8eSTP122G\u83b7\u5f97IND\u540e\uff0c\u96c6\u56e2\u9884\u8ba1\u4e8e2023\u5e74\u7b2c\u56db\u5b63\u5ea6\u53ca2024\u5e74\u4e0a\u534a\u5e74\u5c31GalAhead&#x2122;\u9012\u9001\u5e73\u53f0\u7684\u4f18\u8d28\u8d44\u4ea7STP125G\u53caSTP144G\u4e8e\u7f8e\u56fd\u63d0\u4ea4IND\u7533\u8bf7\u3002<\/p>\n<p><b><u>\u900f\u8fc7\u4e8e\u5e7f\u5dde\u5efa\u7acb\u704c\u88c5\u53ca\u6210\u54c1\u5de5\u5382\uff0c\u4e3a\u672a\u6765\u53d1\u5c55\u5960\u5b9a\u57fa\u7840<\/u><\/b><\/p>\n<p>\u96c6\u56e2\u7684\u5e7f\u5dde\u704c\u88c5\u53ca\u6210\u54c1\u5de5\u5382\u5df2\u7ecf\u6210\u529f\u8fd0\u8425\u4e00\u5e74\uff0c\u5e76\u7ee7\u7eed\u652f\u6301\u96c6\u56e2\u4f18\u5316\u4e8e\u4e9a\u6d32\u7684\u4e34\u5e8a\u4f9b\u5e94\u6218\u7565\u3002\u5de5\u5382\u7684GMP\u5408\u89c4\u6027\u53ca\u65e0\u83cc\u52a0\u5de5\u8fd0\u884c\u4fdd\u969c\u6301\u7eed\u6539\u5584\u3002\u8fd1\u671f\u751f\u4ea7\u7528\u4e8e\u4eba\u4f53\u6ce8\u5c04\u7684STP707\u7684\u5b8c\u6574GMP\u6279\u6b21\u540e\uff0c\u5de5\u5382\u9884\u671f\u80fd\u5168\u9762\u6309\u7167GMP\u89c4\u8303\u751f\u4ea7\u96c6\u56e2\u7684\u7ba1\u7ebf\u4ea7\u54c1\uff0c\u5305\u62ec\u6db2\u4f53\u53ca\u56fa\u4f53\u836f\u5242\u7684\u5236\u5242\u3001\u704c\u88c5\u53ca\u5c01\u88c5\u3001\u68c0\u6d4b\u53ca\u653e\u884c\u3002\u5176\u9884\u8ba1\u5e74\u4ea7\u80fd\u7ea6\u4e3a50,000\u74f6\u4eba\u4f53\u6ce8\u5c04\u7528\u51bb\u5e72\u56fa\u4f53\u5242\u53ca150,000\u81f3200,000\u74f6\u6db2\u4f53\u5242\u91cf\uff0c\u8db3\u4ee5\u652f\u6301\u96c6\u56e2\u76ee\u524d\u8ba1\u5212\u4e2d\u7684\u4e34\u5e8a\u8bd5\u9a8c\u53ca\u672a\u6765\u4e34\u5e8a\u53d1\u5c55\u3002\u4e8e2023\u5e74\u4e0a\u534a\u5e74\uff0c\u5e7f\u5dde\u5de5\u5382\u4e3b\u8981\u652f\u6301\u96c6\u56e2\u7684STP707\u9879\u76ee\uff0c\u4ea6\u542f\u52a8\u4e86GalAhead&#x2122;\u5e73\u53f0\u7684\u704c\u88c5\u7ebf\u4ea7\u80fd\u6269\u5f20\u3002\u5de5\u5382\u8ba1\u5212\u8fdb\u4e00\u6b65\u63d0\u5347\u4ea7\u80fd\uff0c\u4ee5\u652f\u6301\u96c6\u56e2\u4e0d\u65ad\u589e\u957f\u7684GalAhead&#x2122;\u4ea7\u54c1\u7ebf\u3002<\/p>\n<p><b><u>\u6218\u7565\u6027\u52a0\u5f3a\u9999\u6e2f\u4e1a\u52a1\u5e03\u5c40\uff0c\u81f4\u529b\u5c06\u9999\u6e2f\u53d1\u5c55\u6210\u4e3a\u4e9a\u6d32\u9886\u5148\u7684<\/u><\/b><b><u>RNA<\/u><\/b><b><u>\u533b\u836f\u6e2f<\/u><\/b><\/p>\n<p>Sirnaomics\u4e8e2021\u5e74\u5e95\u5728\u9999\u6e2f\u4e0a\u5e02\u540e\uff0c\u4fbf\u4f5c\u51fa\u5728\u9999\u6e2f\u5efa\u7acb\u5177\u6709\u7814\u53d1\u80fd\u529b\u7684\u91cd\u8981\u636e\u70b9\u7684\u6218\u7565\u51b3\u7b56\u3002\u8fc4\u4eca\u4e3a\u6b62\uff0cSirnaomics\u53ca\u5176\u9644\u5c5e\u516c\u53f8RNAimmune\u53caEDIRNA\u5747\u5df2\u4e8e\u9999\u6e2f\u8bbe\u7acb\u529e\u4e8b\u5904\uff0c\u5e76\u5df2\u8fdb\u9a7b\u9999\u6e2f\u79d1\u6280\u56ed\u3002\u6b64\u5916\uff0cSirnaomics\u5df2\u83b7\u5f97\u9999\u6e2f\u79d1\u6280\u56ed\u4e34\u5e8a\u8f6c\u5316\u50ac\u5316\u8ba1\u52128\u767e\u4e07\u6e2f\u5143\uff0c\u4ee5\u53ca\u9999\u6e2f\u79d1\u6280\u56ed\u533b\u7597\u79d1\u6280\u5408\u4f5c\u8ba1\u52122\u767e\u4e07\u6e2f\u5143\u7684\u8d44\u52a9\u3002\u96c6\u56e2\u7684\u76ee\u6807\u662f\u4e0eRNA\u836f\u7269\u76f8\u5173\u7684\u7814\u53d1\u548c\u4e34\u5e8a\u7814\u7a76\u8fdb\u884c\u5408\u4f5c\uff0c\u53ca\u4e8e\u843d\u9a6c\u6d32\u6cb3\u5957\u5730\u533a\u5efa\u7acb\u5177\u5546\u4e1a\u89c4\u6a21\u7684\u751f\u4ea7\u8ba1\u5212\u3002<\/p>\n<p><b>Sirnaomics<\/b><b>\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u3001\u6267\u884c\u8463\u4e8b\u3001\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u9646\u9633\u535a\u58eb<\/b>\u8868\u793a\uff1a<span id=\"spanHghlt8c4f\">\u201c<\/span>\u51ed\u501f\u6211\u4eec\u4e13\u6709\u7684\u53cc\u91cd\u9012\u9001\u6280\u672f\u5e73\u53f0PNP\u53caGalAhead&#x2122;\u3001\u9886\u5148\u7684\u4e34\u5e8a\u9879\u76ee\u53ca\u6210\u719f\u7684\u7814\u53d1\u53ca\u751f\u4ea7\u8bbe\u65bd\uff0c\u6211\u4eec\u5f97\u4ee5\u5c06\u5019\u9009\u836f\u7269\u63a8\u8fdb\u81f3\u4e0d\u540c\u7684\u5f00\u53d1\u9636\u6bb5\uff0c\u5e76\u53d6\u5f97\u79ef\u6781\u7684\u6210\u679c\u3002\u6b64\u5916\uff0c\u5e7f\u5dde\u5de5\u5382\u8fd0\u884c\u5e73\u7a33\u9ad8\u6548\uff0c\u4e0d\u4ec5\u5c55\u73b0\u4e86\u6211\u4eec\u7684\u751f\u4ea7\u80fd\u529b\uff0c\u66f4\u6807\u5fd7\u7740\u96c6\u56e2\u7531\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u5236\u836f\u516c\u53f8\u7684\u987a\u5229\u8f6c\u578b\u3002\u6211\u4eec\u4ea6\u5bf9\u83b7\u5f97\u9999\u6e2f\u79d1\u6280\u56ed\u7684\u8d44\u52a9\u611f\u5230\u6b23\u559c\uff0c\u663e\u793a\u4ed6\u4eec\u5bf9\u6211\u4eec\u56e2\u961f\u5bf9\u521b\u65b0\u7684\u575a\u5b9a\u627f\u8bfa\u53ca\u5c65\u884c\u6539\u5584\u60a3\u8005\u751f\u6d3b\u4f7f\u547d\u7684\u8ba4\u53ef\u3002\u5c55\u671b\u672a\u6765\uff0c\u6211\u4eec\u5c06\u81f4\u529b\u5de9\u56fa\u7ade\u4e89\u4f18\u52bf\u3001\u5bfb\u6c42\u5168\u7403\u53ca\u672c\u5730\u5408\u4f5c\uff0c\u52a0\u5feb\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u8d44\u4ea7\u7684\u5f00\u53d1\uff0c\u6269\u5927\u5e02\u573a\u8986\u76d6\u8303\u56f4\uff0c\u6700\u7ec8\u6539\u5584\u5168\u4e16\u754c\u60a3\u8005\u7684\u798f\u7949\u53ca\u751f\u6d3b\u3002<span id=\"spanHghlt6662\">\u201d<\/span><\/p>\n<p><b><u>\u5173\u4e8e<\/u><\/b><b><u>Sirnaomics Ltd. (<\/u><\/b><b><u>\u80a1\u4efd\u4ee3\u53f7<\/u><\/b><b><u>: 2257)<\/u><\/b><\/p>\n<p>Sirnaomics\u662f\u4e00\u5bb6RNA\u7597\u6cd5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u516c\u53f8\u5019\u9009\u4ea7\u54c1\u5904\u4e8e\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1\u521b\u65b0\u836f\u7269\uff0c\u7528\u4e8e\u6cbb\u7597\u5177\u6709\u533b\u7597\u9700\u6c42\u53ca\u5e9e\u5927\u5e02\u573a\u673a\u4f1a\u7684\u9002\u5e94\u75c7\u3002Sirnaomics\u662f\u9996\u5bb6\u4e8e\u4e9a\u6d32\u548c\u7f8e\u56fd\u5747\u62e5\u6709\u91cd\u8981\u5e02\u573a\u5730\u4f4d\u7684\u4e34\u5e8a\u9636\u6bb5RNA\u7597\u6cd5\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u51ed\u501f\u5176\u4e13\u6709\u7684\u9012\u9001\u6280\u672f\uff1a\u591a\u80bd\u7eb3\u7c73\u9897\u7c92\u9012\u9001\u5e73\u53f0\u548c\u7b2c\u4e8c\u4ee3GalNAc\u5076\u8054\u7269\u9012\u9001\u5e73\u53f0\uff0c\u672c\u96c6\u56e2\u5df2\u5efa\u7acb\u975e\u5e38\u4e30\u5bcc\u7684\u5019\u9009\u836f\u7269\u7ba1\u7ebf\u3002\u968f\u7740\u516c\u53f8STP705\u548cSTP707\u7684\u4e34\u5e8a\u9879\u76ee\u53d6\u5f97\u591a\u9879\u6210\u529f\uff0cSirnaomics\u76ee\u524d\u5728\u63a8\u8fdb\u80bf\u7624\u6cbb\u7597\u7684RNAi\u836f\u7269\u65b9\u9762\u5904\u4e8e\u56fd\u9645\u9886\u5148\u5730\u4f4d\u3002STP122G\u662f\u9996\u6b3e\u8fdb\u5165\u4e34\u5e8a\u7814\u53d1\u9636\u6bb5\u7684GalAhead&#x2122;\u6280\u672f\u5019\u9009\u836f\u7269\u3002\u968f\u7740Sirnaomics\u4e34\u5e8a\u751f\u4ea7\u8bbe\u65bd\u7684\u5efa\u7acb\uff0c\u672c\u96c6\u56e2\u76ee\u524d\u6b63\u5728\u5b9e\u73b0\u4ece\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u5236\u836f\u516c\u53f8\u7684\u8dc3\u8fdb\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u516c\u53f8\u8d44\u8baf\uff0c\u53ef\u6d4f\u89c8\uff1a<a 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