{"id":9303,"date":"2020-11-11T20:00:00","date_gmt":"2020-11-11T13:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/202011112000009303"},"modified":"2020-11-11T21:47:22","modified_gmt":"2020-11-11T13:47:22","slug":"%e5%a4%a9%e5%a2%83%e7%94%9f%e7%89%a9%e5%9c%a82020%e5%b9%b4sitc%e5%b9%b4%e4%bc%9a%e4%b8%8a%e5%85%ac%e5%b8%83tj210-mor210%e4%b8%b4%e5%ba%8a%e5%89%8d%e6%95%b0%e6%8d%ae","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/202011112000009303","title":{"rendered":"\u5929\u5883\u751f\u7269\u57282020\u5e74SITC\u5e74\u4f1a\u4e0a\u516c\u5e03TJ210\/MOR210\u4e34\u5e8a\u524d\u6570\u636e"},"content":{"rendered":"<p><p><span class=\"xn-subheadline\">\u5927\u4f1a\u62a5\u544a\u7740\u91cd\u5c55\u793a\u4e86TJ210\/MOR210\u7684\u6f5c\u5728\u4f5c\u7528\u673a\u5236\u548c\u6297\u80bf\u7624\u7279\u6027<\/span><\/p>\n<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/APAC_Logo-7.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4e2d\u56fd\u4e0a\u6d77\u548c\u7f8e\u56fd\u76d6\u745f\u65af\u58212020\u5e7411\u670811\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u5929\u5883\u751f\u7269\uff08\u201c\u516c\u53f8\u201d\uff09\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aIMAB\uff09\u662f\u4e00\u5bb6\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u521b\u65b0\u751f\u7269\u836f\u7684\u9776\u70b9\u53d1\u73b0\u3001\u4e34\u5e8a\u5f00\u53d1\u548c\u4ea7\u54c1\u5546\u4e1a\u5316\uff0c\u4e3a\u5168\u7403\u8303\u56f4\u5185\u6cbb\u7597\u9700\u6c42\u8feb\u5207\u7684\u764c\u75c7\u6cbb\u7597\u9886\u57df\u63d0\u4f9b\u65b0\u578b\u6709\u6548\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u516c\u53f8\u4eca\u5929\u5728\u7b2c35\u5c4a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u5b66\u4f1a\u5e74\u4f1a\uff08SITC 2020\uff09\u7ebf\u4e0a\u5927\u4f1a\u4e0a\u516c\u5e03\u4e86\u5176C5aR\u6297\u4f53\u9879\u76eeTJ210\/MOR210\u5728\u4f53\u5916\u548c\u4f53\u5185\u7814\u7a76\u4e2d\u7684\u6700\u65b0\u4e34\u5e8a\u524d\u6570\u636e\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>\u8865\u4f53\u7247\u6bb5C5a\u53d7\u4f53\uff08C5aR1\uff0cCD88\uff09\u662f\u4e00\u79cdG\u86cb\u767d\u5076\u8054\u53d7\u4f53\uff08GPCR\uff09\uff0c\u7814\u7a76\u8bc1\u660e\u5176\u662f\u80bf\u7624\u514d\u75ab\u9886\u57df\u7684\u521b\u65b0\u9776\u70b9\u3002\u5728\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff0cC5a\u4f5c\u4e3a\u4e00\u79cd\u8d8b\u5316\u56e0\u5b50\uff0c\u62db\u52df\u8868\u8fbeC5aR1\u7684\u514d\u75ab\u6291\u5236\u6027\u7ec6\u80de\uff0c\u5982\u9ad3\u6e90\u6027\u6291\u5236\u7ec6\u80de\u3001\u4e2d\u6027\u7c92\u7ec6\u80de\u548cM2\u578b\u5de8\u566c\u7ec6\u80de\u7b49\u8fc1\u79fb\u81f3\u80bf\u7624\u90e8\u4f4d\uff0c\u4ece\u800c\u6539\u53d8\u80bf\u7624\u5fae\u73af\u5883\u8fdb\u4e00\u6b65\u6291\u5236\u673a\u4f53\u514d\u75ab\u7ec6\u80de\u5bf9\u80bf\u7624\u7684\u653b\u51fb\uff0c\u4fc3\u8fdb\u80bf\u7624\u53d1\u751f\u53ca\u8fdb\u5c55\u3002<\/p>\n<p>TJ210\/MOR210\u662f\u5929\u5883\u751f\u7269\u4e0eMorphoSys\u516c\u53f8\u5408\u4f5c\u7684\u62ee\u6297\u578bC5aR\u5355\u514b\u9686\u6297\u4f53\u3002\u5b83\u901a\u8fc7\u4e0eC5aR1\u7684N\u7aef\u7ed3\u5408\uff0c\u963b\u65adC5a\u548cC5aR1\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u6291\u5236\u8868\u8fbeC5aR1\u7684\u9776\u7ec6\u80de\u7684\u6fc0\u6d3b\u548c\u8fc1\u79fb\uff0c\u4ece\u800c\u8d77\u5230\u80bf\u7624\u6291\u5236\u7684\u4f5c\u7528\u3002\u4e34\u5e8a\u524d\u7ed3\u679c\u663e\u793a\uff1a<\/p>\n<ul type=\"disc\">\n<li>TJ210\/MOR210\u53ef\u4ee5\u9ad8\u4eb2\u548c\u529b\u5730\u4e0eC5aR1\u7ed3\u5408\uff0c\u5e76\u4e14\u7279\u5f02\u5730\u8bc6\u522b\u5176N\u7aef\u7684\u72ec\u7279\u8868\u4f4d\uff1b <\/li>\n<li>TJ210\/MOR210\u963b\u65adC5a\/C5aR\u7684\u901a\u8def\u80fd\u591f\u51cf\u5c11\u514d\u75ab\u6291\u5236\u6027\u7ec6\u80de\u52df\u96c6\uff0c\u5728\u4e0e\u5176\u4ed6\u80bf\u7624\u514d\u75ab\u7597\u6cd5\uff08\u5982PD-1\u6297\u4f53\uff09\u8054\u7528\u65f6\u5176\u5bf9\u80bf\u7624\u7684\u6291\u5236\u4f5c\u7528\u5c24\u4e3a\u660e\u663e\uff1b <\/li>\n<li>\u4e3a\u671f4\u5468\u7684\u98df\u87f9\u7334GLP\u91cd\u590d\u7ed9\u836f\u6bd2\u6027\u7814\u7a76\u8868\u660e\uff0cTJ210\/MOR210\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c\u5728\u6700\u9ad8\u81f3200mg\/kg\u7684\u5242\u91cf\u4e0b\u672a\u89c2\u5bdf\u5230\u4e0d\u826f\u53cd\u5e94\uff0c\u4e2d\u6027\u7c92\u7ec6\u80de\u4ea6\u672a\u53d7\u5f71\u54cd\u3002<\/li>\n<\/ul>\n<p>\u5929\u5883\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u7533\u534e\u743c\u535a\u58eb\u8868\u793a\uff1a\u201cTJ210\/MOR210\u662f\u4e00\u6b3e\u5177\u6709\u5dee\u5f02\u5316\u4f18\u52bf\u7684\u521b\u65b0\u6027\u5355\u514b\u9686\u6297\u4f53\uff0c\u662f\u5929\u5883\u751f\u7269\u4e30\u5bcc\u7684\u7814\u53d1\u7ba1\u7ebf\u4e2d\u6781\u5177\u6f5c\u529b\u7684\u80bf\u7624\u514d\u75ab\u7814\u7a76\u836f\u7269\u4e4b\u4e00\u3002\u6211\u4eec\u8feb\u5207\u671f\u671b\u5c06\u8fd9\u4e00\u521b\u65b0\u9879\u76ee\u63a8\u8fdb\u81f3\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\uff0c\u4ee5\u89e3\u51b3\u5168\u7403\u764c\u75c7\u60a3\u8005\u5c1a\u5f85\u6ee1\u8db3\u7684\u9700\u6c42\u3002\u201d<\/p>\n<p>\u53e3\u5934\u62a5\u544a\u8be6\u7ec6\u4fe1\u606f\u5982\u4e0b\uff1a<\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"1\" class=\"prntblns\">\n<tbody>\n<tr>\n<td nowrap class=\"prnsbts prnrbrs prnvam prnsbbs prnpl6 prnsbls prnpr6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u6807\u9898<\/b><\/span><\/p>\n<\/td>\n<td nowrap class=\"prnsbts prnrbrs prnvab prnsbbs prnpl6 prnsbl1 prnpr6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>TJ210 (MOR210), A Differentiated Anti-C5aR Antibody for Anti-Cancer Therapy<\/b><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>TJ210 (MOR210),<\/b>&nbsp;<b>\u4e00\u79cd\u7528\u4e8e\u764c\u75c7\u6cbb\u7597\u7684\u5dee\u5f02\u5316<\/b><b>C5aR<\/b><b>\u6297\u4f53<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u6458\u8981\u7f16\u53f7<\/b><b>#<\/b><\/span><\/p>\n<\/td>\n<td nowrap class=\"prnsbt1 prnrbrs prnvab prnsbbs prntal prnpl6 prnsbl1 prnpr6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">607<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u62a5\u544a\u8005<\/b><\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u5b5f\u7504\u535a\u58eb\uff0c\u5929\u5883\u751f\u7269<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u62a5\u544a\u65f6\u95f4<\/b><\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">11\u670812\u65e5\u661f\u671f\u56db&nbsp;\u4e0a\u534811:30&nbsp;&#8211; 11:45\uff08\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f4\uff09<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>\u6b64\u6b21\u516c\u5e03\u7684\u4e34\u5e8a\u524d\u6570\u636e\u63ed\u793a\u4e86TJ210\/MOR210\u7684\u521b\u65b0\u4f5c\u7528\u673a\u5236\uff0c\u4e3a\u8fdb\u4e00\u6b65\u8bc4\u4f30TJ210\/MOR210\u4f5c\u4e3a\u6f5c\u5728\u7684\u764c\u75c7\u6cbb\u7597\u836f\u7269\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u79d1\u5b66\u4f9d\u636e\u3002\u5929\u5883\u751f\u7269\u548cMorphoSys\u516c\u53f8\u8fd1\u671f\u8054\u5408\u5ba3\u5e03\uff0cTJ210\/MOR210\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u665a\u671f\u5b9e\u4f53\u7624\u76841\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff08IND\uff09\u5df2\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u3002<\/p>\n<p><b>\u5173\u4e8e<\/b><b>TJ210\/MOR210<\/b><\/p>\n<p>TJ210\/MOR210\u662f\u5929\u5883\u751f\u7269\u6388\u6743\u81eaMorphoSys\u516c\u53f8\u7684HuCAL Platinum<sup>&reg;<\/sup>\u6280\u672f\u5e76\u5408\u4f5c\u5f00\u53d1\u7684\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u764c\u75c7\u7684\u65b0\u578bC5aR\u5355\u514b\u9686\u6297\u4f53\u3002C5aR\u4f5c\u4e3a\u8865\u4f53\u56e0\u5b50C5a\u7684\u53d7\u4f53\uff0c\u662f\u80bf\u7624\u514d\u75ab\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7814\u7a76\u7684\u6f5c\u5728\u9776\u70b9\u3002\u80bf\u7624\u7ec6\u80de\u53ef\u4ee5\u4ea7\u751f\u5927\u91cfC5a\u5e76\u901a\u8fc7\u62db\u52df\u548c\u6fc0\u6d3b\u9ad3\u6e90\u6027\u6291\u5236\u7ec6\u80de\uff08MDSCs\uff09\u3001M2\u578b\u5de8\u566c\u7ec6\u80de\u548c\u4e2d\u6027\u7c92\u7ec6\u80de\u800c\u88ab\u8ba4\u4e3a\u6709\u52a9\u4e8e\u5f62\u6210\u514d\u75ab\u6291\u5236\u7684\u4fc3\u80bf\u7624\u5fae\u73af\u5883\u3002TJ210\/MOR210\u65e8\u5728\u963b\u65adC5a\u4e0e\u5176\u53d7\u4f53\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u4ece\u800c\u53ef\u80fd\u6291\u5236MDSCs\u7684\u514d\u75ab\u6291\u5236\u529f\u80fd\uff0c\u4f7f\u514d\u75ab\u7ec6\u80de\u80fd\u591f\u653b\u51fb\u80bf\u7624\u3002<\/p>\n<p>HuCAL Platinum<sup>&reg;<\/sup>\u662fMorphoSys\u516c\u53f8\u7684\u6ce8\u518c\u5546\u6807\u3002<\/p>\n<p><b>\u5173\u4e8e\u5929\u5883\u751f\u7269<\/b><\/p>\n<p>\u5929\u5883\u751f\u7269\u662f\u4e00\u5bb6\u5bcc\u6709\u6d3b\u529b\u7684\u56fd\u9645\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u805a\u7126\u80bf\u7624\u514d\u75ab\u548c\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u9886\u57df\u5dee\u5f02\u5316\u521b\u65b0\u751f\u7269\u836f\u7684\u7814\u53d1\uff0c\u4ee5\u201c\u6301\u7eed\u5f00\u53d1\u521b\u65b0\u751f\u7269\u836f\uff0c\u771f\u6b63\u6539\u53d8\u60a3\u8005\u751f\u6d3b\u201d\u4e3a\u4f7f\u547d\u3002\u5929\u5883\u751f\u7269\u5728\u201c\u5feb\u901f\u4ea7\u54c1\u4e0a\u5e02\u201d\u548c\u201c\u5feb\u901f\u6982\u5ff5\u9a8c\u8bc1\u201d\u7684\u53cc\u8f6e\u7b56\u7565\u9a71\u52a8\u4e0b\uff0c\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\u548c\u5168\u7403\u5408\u4f5c\u7b49\u591a\u5143\u5316\u6a21\u5f0f\uff0c\u8fc5\u901f\u5efa\u7acb\u8d77\u62e5\u6709\u5341\u591a\u4e2a\u5177\u6709\u5168\u7403\u7ade\u4e89\u529b\u7684\u521b\u65b0\u836f\u7814\u53d1\u7ba1\u7ebf\u3002\u5929\u5883\u751f\u7269\u51ed\u501f\u4f18\u79c0\u7684\u836f\u7269\u7814\u53d1\u56e2\u961f\u3001\u500d\u53d7\u8ba4\u53ef\u7684\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u5f00\u53d1\u5b9e\u529b\uff0c\u4ee5\u53ca\u4e16\u754c\u4e00\u6d41\u7684GMP\u751f\u4ea7\u80fd\u529b\uff0c\u6b63\u5feb\u901f\u6210\u957f\u4e3a\u8986\u76d6\u5168\u4ea7\u4e1a\u94fe\u7684\u7efc\u5408\u6027\u5168\u7403\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u5929\u5883\u751f\u7269\u5728\u5317\u4eac\u3001\u4e0a\u6d77\u3001\u676d\u5dde\u3001\u9999\u6e2f\u548c\u7f8e\u56fd\u9a6c\u91cc\u5170\u5dde\u5747\u8bbe\u6709\u529e\u516c\u5ba4\u3002\u66f4\u591a\u4fe1\u606f\u8bf7\u8bbf\u95ee<u><a target=\"_blank\" href=\"http:\/\/ir.i-mabbiopharma.com\/\" rel=\"nofollow noopener noreferrer\">http:\/\/ir.i-mabbiopharma.com<\/a><\/u>\u5e76\u5173\u6ce8\u5929\u5883\u751f\u7269<u><a target=\"_blank\" href=\"https:\/\/www.linkedin.com\/company\/i-mab\/\" rel=\"nofollow noopener noreferrer\">\u9886\u82f1<\/a><\/u>\u3001<a target=\"_blank\" href=\"https:\/\/twitter.com\/IMabBiopharma\" rel=\"nofollow noopener noreferrer\">\u63a8\u7279<\/a>\u53ca<u><a target=\"_blank\" href=\"https:\/\/mp.weixin.qq.com\/s\/_s634aizyQPuq1Vgf-hLGA\" rel=\"nofollow noopener noreferrer\">\u5fae\u4fe1<\/a><\/u>\u5b98\u65b9\u8d26\u53f7\u3002<\/p>\n<p><b>\u5929\u5883\u751f\u7269\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u5305\u542b\u6839\u636e\u300a1995 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cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td nowrap class=\"prngen7\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u6731\u6770\u4f26\uff0c\u9996\u5e2d\u8d22\u52a1\u5b98<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><u><a target=\"_blank\" href=\"mailto:jielun.zhu@i-mabbiopharma.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\">jielun.zhu@i-mabbiopharma.com<\/a><\/u><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+86 21 6057 8000<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen7\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u51af\u7426\uff0c\u9996\u5e2d\u4f20\u64ad\u5b98<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><u><a target=\"_blank\" href=\"mailto:gigi.feng@i-mabbiopharma.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\">gigi.feng@i-mabbiopharma.com<\/a><\/u><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+86 21 6057 5785<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p><b>\u6295\u8d44\u8005\u54a8\u8be2<\/b><\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prngen7\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><i>Burns McClellan, Inc. (<\/i><i>\u7f8e\u56fd\u548c\u6b27\u6d32<\/i><i>)<\/i><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">Steve Klass<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><u><a target=\"_blank\" href=\"mailto:sklass@burnsmc.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\">sklass@burnsmc.com<\/a><\/u><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+1 212 213 0006<\/span><\/p>\n<\/td>\n<td class=\"prngen7\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><i>The Piacente Group, Inc.&nbsp;(<\/i><i>\u4e9a\u6d32\uff09<\/i><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">Emilie Wu<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><u><a target=\"_blank\" href=\"mailto:emilie@thepiacentegroup.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\">emilie@thepiacentegroup.com<\/a><\/u><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+86 21 6039 8363<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder2\">  <\/div>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>http:\/\/www.i-mabbiopharma.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5927\u4f1a\u62a5\u544a\u7740\u91cd\u5c55\u793a\u4e86TJ210\/MOR210\u7684\u6f5c\u5728\u4f5c\u7528\u673a\u5236\u548c\u6297\u80bf\u7624\u7279\u6027 \u4e2d\u56fd\u4e0a\u6d77\u548c\u7f8e\u56fd\u76d6\u745f\u65af\u58212020\u5e7411\u670811\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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