{"id":92503,"date":"2023-08-22T18:30:00","date_gmt":"2023-08-22T11:30:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023082218300092503"},"modified":"2023-08-23T16:08:19","modified_gmt":"2023-08-23T08:08:19","slug":"%e7%a7%91%e6%b5%8e%e8%8d%af%e4%b8%9a%e5%8f%91%e5%b8%832023%e4%b8%ad%e6%9c%9f%e4%b8%9a%e7%bb%a9","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023082218300092503","title":{"rendered":"\u79d1\u6d4e\u836f\u4e1a\u53d1\u5e032023\u4e2d\u671f\u4e1a\u7ee9"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/Logo-500.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><p><span class=\"legendSpanClass\">\u4e0a\u6d77<\/span><span class=\"legendSpanClass\">2023\u5e748\u670822\u65e5<\/span> \/\u7f8e\u901a\u793e\/ 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NCT04581473\uff09\uff0c\u4ee5\u53ca\u4e00\u9879\u7814\u7a76\u8005\u53d1\u8d77\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT03874897\uff09\u30022023\u5e748\u670821\u65e5\uff0c\u79d1\u6d4e\u836f\u4e1a\u5ba3\u5e03\u4e0e\u7f8e\u5fb7\u7eb3\u516c\u53f8\uff08Nasdaq: MRNA\uff09\u5df2\u542f\u52a8\u4e86\u4e00\u9879\u5408\u4f5c\u534f\u8bae\uff0c\u4ee5\u7814\u7a76CT041\u4e0e\u7f8e\u5fb7\u7eb3\u7684\u8bd5\u9a8c\u6027Claudin18.2 mRNA\u764c\u75c7\u75ab\u82d7\u7684\u7ec4\u5408\u6548\u679c\u3002<\/p>\n<p>\u9664\u4e86\u4e0a\u8ff0\u7684\u73b0\u6709\u4e34\u5e8a\u9879\u76ee\uff0c\u79d1\u6d4e\u5c06\u79ef\u6781\u63a2\u7d22\u521b\u65b0CAR-T\u7ec6\u80de\u4ea7\u54c1\u7528\u4e8e\u65e9\u671f\u6cbb\u7597\u65b9\u6cd5\u3002\u516c\u53f8\u4ea6\u5df2\u52aa\u529b\u5f00\u53d1\u521b\u65b0\u6280\u672f\u548c\u5019\u9009\u4ea7\u54c1\uff0c\u4ee5\u66f4\u597d\u5730\u5e94\u5bf9\u73b0\u6709\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u9762\u4e34\u7684\u6311\u6218\u3002\u622a\u81f32023\u5e746\u670830\u65e5\uff0c\u6211\u4eec\u62e5\u6709300\u591a\u9879\u4e13\u5229\uff0c\u5176\u4e2d\u6709101\u9879\u4e3a\u5168\u7403\uff08\u5305\u62ec\u4e2d\u56fd\u3001\u7f8e\u56fd\u3001\u6b27\u6d32\u53ca\u65e5\u672c\uff09\u6388\u6743\u4e13\u5229\u3002\u76f8\u8f832022\u5e74\u5e95\uff0c\u65b0\u589e\u4e869\u9879\u6388\u6743\u4e13\u5229\u53ca24\u9879\u4e13\u5229\u7533\u8bf7\u3002\u6211\u4eec\u7684\u7814\u7a76\u6d3b\u52a8\u5c06\u7ee7\u7eed\u5728\u6211\u4eec\u7684\u4e13\u4e1a\u9886\u57df\u5185\u4ea7\u751f\u6570\u91cf\u53ef\u89c2\u7684\u77e5\u8bc6\u4ea7\u6743\u3002<\/p>\n<p>\u6211\u4eec\u5df2\u7ecf\u9488\u5bf9CAR-T\u5236\u9020\u7684\u4e09\u4e2a\u5173\u952e\u9636\u6bb5\u5efa\u7acb\u4e86\u72ec\u7acb\u81ea\u4e3b\u7684\u5185\u90e8\u5782\u76f4\u4e00\u4f53\u5316\u7684\u751f\u4ea7\u80fd\u529b\uff0c\u5305\u62ec\u8d28\u7c92\u751f\u4ea7\u3001\u6162\u75c5\u6bd2\u8f7d\u4f53\u751f\u4ea7\u53caCAR-T\u7ec6\u80de\u751f\u4ea7\u3002\u6211\u4eec\u6301\u7eed\u5728\u4e2d\u56fd\u53ca\u7f8e\u56fd\u6269\u5f20\u5168\u7403\u4ea7\u80fd\uff0c\u4ee5\u652f\u6301\u4e34\u5e8a\u8bd5\u9a8c\u53ca\u968f\u540e\u6211\u4eec\u7ba1\u7ebf\u4ea7\u54c1\u7684\u5546\u4e1a\u5316\u3002\u901a\u8fc7\u4f4d\u4e8e\u4e0a\u6d77\u5f90\u6c47\u7684\u4e34\u5e8a\u751f\u4ea7\u5382\u623f\u53ca\u4f4d\u4e8e\u4e0a\u6d77\u91d1\u5c71\u7684\u5546\u4e1a\u5316GMP\u751f\u4ea7\u5382\u623f\uff0c\u6211\u4eec\u81ea\u4e3b\u751f\u4ea7CAR-T\u7ec6\u80de\u4ea7\u54c1\u4ee5\u652f\u6301\u4e2d\u56fd\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u81ea\u4e3b\u751f\u4ea7\u6162\u75c5\u6bd2\u8f7d\u4f53\u4ee5\u652f\u6301\u5168\u7403\u4e34\u5e8a\u8bd5\u9a8c\u3002\u6211\u4eec\u4f4d\u4e8e\u5317\u5361\u7f57\u6765\u7eb3\u5dde\u8fbe\u52d2\u59c6\u7684\u4e09\u89d2\u7814\u7a76\u56ed\uff08RTP\uff09CGMP\u751f\u4ea7\u5de5\u5382\u5df2\u7ecf\u5f00\u59cb\u81ea\u4f53CAR-T\u7ec6\u80de\u4ea7\u54c1\u7684GMP\u751f\u4ea7\u3002RTP\u751f\u4ea7\u5de5\u5382\u5c06\u4e3a\u79d1\u6d4e\u63d0\u4f9b\u6bcf\u5e74\u4e3a700\u540d\u60a3\u8005\u751f\u4ea7\u81ea\u4f53CAR-T\u7ec6\u80de\u4ea7\u54c1\u7684\u989d\u5916\u4ea7\u80fd\uff0c\u5c06\u7528\u4e8e\u652f\u6301\u5728\u7f8e\u56fd\u3001\u52a0\u62ff\u5927\u53ca\u6b27\u6d32\u7684\u4e34\u5e8a\u7814\u7a76\u548c\u65e9\u671f\u5546\u4e1a\u5316\u3002<\/p>\n<p><b>\u5173\u4e8e\u79d1\u6d4e\u836f\u4e1a<\/b><\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\uff08\u80a1\u7968\u4ee3\u7801\uff1a2171.HK\uff09\u662f\u4e00\u5bb6\u5728\u4e2d\u56fd\u53ca\u7f8e\u56fd\u62e5\u6709\u4e1a\u52a1\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u521b\u65b0CAR-T\u7ec6\u80de\u7597\u6cd5\u3002\u6211\u4eec\u5efa\u7acb\u4e86\u4ece\u9776\u70b9\u53d1\u73b0\u3001\u521b\u65b0\u578bCAR-T\u7ec6\u80de\u7814\u5236\u3001\u4e34\u5e8a\u8bd5\u9a8c\u5230\u5546\u4e1a\u89c4\u6a21\u751f\u4ea7\u7684CAR-T\u7ec6\u80de\u7814\u7a76\u4e0e\u5f00\u53d1\u5e73\u53f0\u3002\u6211\u4eec\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\u65b0\u6280\u672f\u4ee5\u53ca\u62e5\u6709\u5168\u7403\u6743\u76ca\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u4ee5\u89e3\u51b3CAR-T\u7ec6\u80de\u7597\u6cd5\u7684\u91cd\u5927\u6311\u6218\uff0c\u6bd4\u5982\u63d0\u9ad8\u5b89\u5168\u6027\uff0c\u63d0\u9ad8\u6cbb\u7597\u5b9e\u4f53\u7624\u7684\u7597\u6548\u548c\u964d\u4f4e\u6cbb\u7597\u6210\u672c\u3002\u6211\u4eec\u7684\u4f7f\u547d\u662f\u6210\u4e3a\u80fd\u4e3a\u5168\u7403\u764c\u75c7\u60a3\u8005\u5e26\u6765\u521b\u65b0\u548c\u5dee\u5f02\u5316\u7684\u7ec6\u80de\u7597\u6cd5\uff0c\u5e76\u4f7f\u764c\u75c7\u53ef\u6cbb\u6108\u7684\u5168\u7403\u751f\u7269\u5236\u836f\u9886\u5bfc\u8005\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u4e2d\u6240\u6709\u4e0d\u5c5e\u4e8e\u5386\u53f2\u4e8b\u5b9e\u6216\u4e0e\u5f53\u524d\u4e8b\u5b9e\u6216\u5f53\u524d\u6761\u4ef6\u65e0\u5173\u7684\u9648\u8ff0\u90fd\u662f\u524d\u77bb\u6027\u9648\u8ff0\u3002\u6b64\u7c7b\u524d\u77bb\u6027\u58f0\u660e\u8868\u8fbe\u4e86\u672c\u96c6\u56e2\u622a\u81f3\u672c\u65b0\u95fb\u7a3f\u53d1\u5e03\u4e4b\u65e5\u5bf9\u672a\u6765\u4e8b\u4ef6\u7684\u5f53\u524d\u89c2\u70b9\u3001\u9884\u6d4b\u3001\u4fe1\u5ff5\u548c\u9884\u671f\u3002\u6b64\u7c7b\u524d\u77bb\u6027\u58f0\u660e\u662f\u57fa\u4e8e\u672c\u96c6\u56e2\u65e0\u6cd5\u63a7\u5236\u7684\u4e00\u4e9b\u5047\u8bbe\u548c\u56e0\u7d20\u3002\u56e0\u6b64\uff0c\u5b83\u4eec\u53d7\u5230\u91cd\u5927\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u4e8b\u4ef6\u6216\u7ed3\u679c\u53ef\u80fd\u4e0e\u8fd9\u4e9b\u524d\u77bb\u6027\u58f0\u660e\u6709\u91cd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\u4e0a\u53d1\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u62a5\u544a\u4e2d\u300c\u4e3b\u8981\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u300d\u6807\u9898\u4e0b\u7684\u8be6\u7ec6\u5185\u5bb9\u3002\u5bf9\u4e8e\u672c\u65b0\u95fb\u7a3f\u4e2d\u7684\u4efb\u4f55\u9884\u6d4b\u3001\u76ee\u6807\u3001\u4f30\u8ba1\u6216\u9884\u6d4b\u7684\u5b9e\u73b0\u6216\u5408\u7406\u6027\uff0c\u6211\u4eec\u4e0d\u4f5c\u4efb\u4f55\u9648\u8ff0\u6216\u4fdd\u8bc1\uff0c\u4e5f\u4e0d\u5e94\u4f9d\u8d56\u8fd9\u4e9b\u9884\u6d4b\u3002<\/p>\n<p><b>\u8054\u7cfb\u79d1\u6d4e\u836f\u4e1a<\/b><\/p>\n<p>\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a<a href=\"https:\/\/www.carsgen.com\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.carsgen.com\/<\/a><br \/>\u5a92\u4f53\u8054\u7cfb\uff1a<a href=\"mailto:PR@carsgen.com\" target=\"_blank\" rel=\"nofollow noopener\">PR@carsgen.com<\/a><\/p>\n<p>&nbsp;<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder0\">\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4e0a\u6d772023\u5e748\u670822\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;&nbsp;\u79d1\u6d4e\u836f\u4e1a\uff08\u80a1\u7968\u4ee3\u7801\uff1a2171.HK\uff09\uff0c\u4e00\u5bb6\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u521b\u65b0CAR-T\u7ec6\u80de\u7597\u6cd5\u516c\u53f8\uff0c\u53d1\u5e03\u4e862023\u4e2d\u671f\u4e1a\u7ee9\u3002 \u4e1a\u7ee9\u4eae\u70b9\u901f\u89c8 \u79d1\u6d4e\u836f\u4e1a\u4e0e\u534e\u4e1c\u533b\u836f\u5c31\u6cfd\u6c83\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5728\u4e2d\u56fd\u5927\u9646\u5730\u533a\u5546\u4e1a\u5316\u7b7e\u8ba2\u5408\u4f5c\u534f\u8bae\u3002 CT041\u83b7\u5f97\u56fd\u5bb6\u836f\u76d1\u5c40\u7684IND\u6279\u51c6\u7528\u4e8eClaudin18.2\u8868\u8fbe\u9633\u6027\u7684\u80f0\u817a\u764c\u672f\u540e\u8f85\u52a9\u6cbb\u7597\u3002 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