{"id":92284,"date":"2023-08-21T15:53:00","date_gmt":"2023-08-21T08:53:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023082115530092284"},"modified":"2023-08-22T15:40:22","modified_gmt":"2023-08-22T07:40:22","slug":"%e7%a7%91%e6%b5%8e%e8%8d%af%e4%b8%9a%e4%b8%8e%e7%be%8e%e5%be%b7%e7%ba%b3%e5%90%88%e4%bd%9c%e4%bb%a5%e8%af%84%e4%bc%b0ct041%e4%b8%8emrna%e7%99%8c%e7%97%87%e7%96%ab%e8%8b%97%e8%81%94%e5%90%88%e6%b2%bb","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023082115530092284","title":{"rendered":"\u79d1\u6d4e\u836f\u4e1a\u4e0e\u7f8e\u5fb7\u7eb3\u5408\u4f5c\u4ee5\u8bc4\u4f30CT041\u4e0emRNA\u764c\u75c7\u75ab\u82d7\u8054\u5408\u6cbb\u7597"},"content":{"rendered":"\n\n\n
\"\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e0a\u6d77\u548c\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865<\/span>2023\u5e748\u670821\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u79d1\u6d4e\u836f\u4e1a\uff08\u80a1\u7968\u4ee3\u7801\uff1a2171.HK\uff09\uff0c\u4e00\u5bb6\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u521b\u65b0CAR-T\u7ec6\u80de\u7597\u6cd5\u516c\u53f8\uff0c\u5ba3\u5e03\u5176\u4e0e\u7f8e\u5fb7\u7eb3\u516c\u53f8\uff08Nasdaq: MRNA\uff09\u5df2\u542f\u52a8\u4e86\u4e00\u9879\u5408\u4f5c\u534f\u8bae\uff0c\u4ee5\u7814\u7a76\u79d1\u6d4e\u836f\u4e1a\u7684Claudin18.2 CAR-T\u5019\u9009\u4ea7\u54c1\uff08CT041\uff09\u4e0e\u7f8e\u5fb7\u7eb3\u7684\u8bd5\u9a8c\u6027Claudin18.2 mRNA\u764c\u75c7\u75ab\u82d7\u7684\u7ec4\u5408\u6548\u679c\u3002<\/p>\n

\n<\/p><\/div>\n

CT041\uff08satricabtagene autoleucel\uff09\u662f\u79d1\u6d4e\u836f\u4e1a\u7684\u81ea\u4f53CAR-T\u7ec6\u80de\u4ea7\u54c1\uff0c\u516c\u53f8\u6b63\u5728\u7814\u7a76\u5176\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\u3001\u80f0\u817a\u764c\u548c\u5176\u4ed6\u7279\u5b9a\u6d88\u5316\u7cfb\u7edf\u80bf\u7624\u7684\u6f5c\u5728\u53ef\u80fd\u6027\uff0c\u76ee\u524d\u5728\u4e2d\u56fd\u548c\u5317\u7f8e\u5f00\u5c55\u591a\u9879\u4e34\u5e8a\u7814\u7a76\u3002\u7f8e\u5fb7\u7eb3\u6b63\u5728\u5f00\u53d1\u4e00\u79cd\u8bd5\u9a8c\u6027\u7684\u73b0\u8d27\u578bmRNA\u764c\u75c7\u75ab\u82d7\uff0c\u8be5\u75ab\u82d7\u7f16\u7801\u9776\u5411\u80bf\u7624\u76f8\u5173\u6297\u539fClaudin18.2\u86cb\u767d\u3002\u6839\u636e\u534f\u8bae\uff0c\u5408\u4f5c\u53cc\u65b9\u4f1a\u5f00\u5c55\u4e34\u5e8a\u524d\u7814\u7a76\u548cI\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u8bc4\u4f30CT041\u4e0e\u7f8e\u5fb7\u7eb3\u7684Claudin18.2 mRNA\u764c\u75c7\u75ab\u82d7\u7684\u8054\u5408\u6cbb\u7597\u6548\u679c\u3002<\/p>\n

"CT041\u662f\u76ee\u524d\u5f00\u53d1\u8fdb\u5ea6\u6700\u9886\u5148\u7684\u5b9e\u4f53\u7624CAR-T\u7ec6\u80de\u7597\u6cd5\uff08\u5904\u4e8e\u5173\u952eII\u671f\u4e34\u5e8a\u9636\u6bb5\uff09\uff0c\u5728\u6cbb\u7597\u80c3\u764c\u548c\u80f0\u817a\u764c\u65b9\u9762\u4e00\u76f4\u5448\u73b0\u51fa\u5149\u660e\u7684\u6cbb\u7597\u524d\u666f\u3002\u4e3a\u4e86\u8ffd\u6c42\u2018\u4f7f\u764c\u75c7\u53ef\u6cbb\u6108’\u7684\u76ee\u6807\uff0c\u6211\u4eec\u4e0d\u65ad\u63a2\u7d22\u591a\u79cd\u9014\u5f84\u6765\u6d88\u9664\u80bf\u7624\u3002\u5c06CAR-T\u7ec6\u80de\u7597\u6cd5\u4e0e\u764c\u75c7\u75ab\u82d7\u8054\u5408\u6cbb\u7597\u80bf\u7624\uff0c\u6709\u53ef\u80fd\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u5927\u7684\u4e34\u5e8a\u83b7\u76ca\u3002"\u79d1\u6d4e\u836f\u4e1a\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u3001\u9996\u5e2d\u6267\u884c\u5b98\u3001\u9996\u5e2d\u79d1\u5b66\u5b98\u674e\u5b97\u6d77\u535a\u58eb\u8868\u793a\uff0c"\u7f8e\u5fb7\u7eb3\u516c\u53f8\u5df2\u5728mRNA\u75ab\u82d7\u548c\u6cbb\u7597\u9886\u57df\u786e\u7acb\u4e86\u79d1\u5b66\u548c\u5546\u4e1a\u4e0a\u7684\u9886\u5bfc\u5730\u4f4d\uff0c\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0e\u7f8e\u5fb7\u7eb3\u5408\u4f5c\uff0c\u63a2\u7d22\u53cc\u65b9\u521b\u65b0\u7597\u6cd5\u7684\u8054\u5408\u6cbb\u7597\u6f5c\u529b\u3002" <\/p>\n

"\u6211\u4eec\u5f88\u8363\u5e78\u4e0e\u79d1\u6d4e\u836f\u4e1a\u5408\u4f5c\uff0c\u5171\u540c\u63a2\u7d22CAR-T\u4e0e\u8bd5\u9a8c\u6027Claudin18.2 mRNA\u764c\u75c7\u75ab\u82d7\u7684\u6f5c\u5728\u534f\u540c\u4f5c\u7528\u3002Claudin18.2\u4f5c\u4e3a\u4e00\u4e2a\u524d\u666f\u5e7f\u9614\u7684\u6cbb\u7597\u9776\u70b9\uff0c\u6709\u671b\u7528\u4e8e\u6cbb\u7597\u591a\u79cd\u533b\u7597\u9700\u6c42\u8feb\u5207\u7684\u764c\u75c7\u7c7b\u578b\u3002\u6211\u4eec\u5c06\u6301\u7eed\u53d1\u6325mRNA\u79d1\u5b66\u7684\u6f5c\u529b\uff0c\u5728\u80bf\u7624\u9886\u57df\u6253\u9020\u65b0\u4e00\u4ee3\u7684\u9769\u547d\u6027\u836f\u7269\u3002" \u7f8e\u5fb7\u7eb3\u5916\u90e8\u7814\u7a76\u521b\u65b0\u9996\u5e2d\u79d1\u5b66\u5b98Lin Guey\u535a\u58eb\u8868\u793a\u3002<\/p>\n

\u5173\u4e8e<\/b>CT041<\/b><\/p>\n

CT041\u662f\u4e00\u79cd\u6f5c\u5728\u5168\u7403\u540c\u7c7b\u9996\u521b\u7684\u3001\u9776\u5411Claudin18.2\u86cb\u767d\u7684\u81ea\u4f53CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\uff0c\u7528\u4e8e\u6cbb\u7597Claudin18.2\u9633\u6027\u5b9e\u4f53\u7624\uff0c\u4e3b\u8981\u6cbb\u7597\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u53ca\u80f0\u817a\u764c\u3002\u79d1\u6d4e\u836f\u4e1a\u6b63\u5728\u8fdb\u884c\u7684\u8bd5\u9a8c\u5305\u62ec\u5728\u4e2d\u56fd\u5f00\u5c55\u7684\u7814\u7a76\u8005\u53d1\u8d77\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT03874897\uff09\uff0c\u9488\u5bf9\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u53ca\u80f0\u817a\u764c\u7684I \u671f\u4e34\u5e8a\u8bd5\u9a8c\u53ca\u9488\u5bf9\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u7684\u786e\u8bc1\u6027II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08CT041-ST-01\uff0cNCT04581473\uff09\uff0c\u5728\u4e2d\u56fd\u5f00\u5c55\u7684\u9488\u5bf9\u80f0\u817a\u764c\u8f85\u52a9\u6cbb\u7597\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08CT041-ST-05, NCT05911217\uff09\uff0c\u4ee5\u53ca\u5728\u5317\u7f8e\u5f00\u5c55\u7684\u9488\u5bf9\u665a\u671f\u80c3\u764c\u6216\u80f0\u817a\u764c\u76841b\/2\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08CT041-ST-02\uff0cNCT04404595\uff09\u30022022\u5e741\u6708\uff0cCT041\u88ab\u7f8e\u56fdFDA\u6388\u4e88"\u518d\u751f\u533b\u5b66\u5148\u8fdb\u7597\u6cd5"\uff08RMAT\uff09\u8ba4\u5b9a\u7528\u4e8e\u6cbb\u7597Claudin18.2\u9633\u6027\u7684\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u30022021\u5e7411\u6708\uff0cCT041\u88abEMA\u6388\u4e88\u4f18\u5148\u836f\u54c1\uff08PRIME\uff09\u8d44\u683c\u6cbb\u7597\u665a\u671f\u80c3\u764c\u30022020\u5e74\u548c2021\u5e74\uff0cCT041\u5206\u522b\u88ab\u7f8e\u56fdFDA\u6388\u4e88"\u5b64\u513f\u836f"\u8ba4\u5b9a\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u548c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u6388\u4e88"\u5b64\u513f\u836f\u4ea7\u54c1"\u8ba4\u5b9a\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u764c\u3002<\/p>\n

\u5173\u4e8e\u79d1\u6d4e\u836f\u4e1a<\/b><\/p>\n

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\u5173\u4e8e\u7f8e\u5fb7\u7eb3<\/b><\/p>\n

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\u79d1\u6d4e\u836f\u4e1a\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n

\u672c\u65b0\u95fb\u7a3f\u4e2d\u6240\u6709\u4e0d\u5c5e\u4e8e\u5386\u53f2\u4e8b\u5b9e\u6216\u4e0e\u5f53\u524d\u4e8b\u5b9e\u6216\u5f53\u524d\u6761\u4ef6\u65e0\u5173\u7684\u9648\u8ff0\u90fd\u662f\u524d\u77bb\u6027\u9648\u8ff0\u3002\u6b64\u7c7b\u524d\u77bb\u6027\u58f0\u660e\u8868\u8fbe\u4e86\u672c\u96c6\u56e2\u622a\u81f3\u672c\u65b0\u95fb\u7a3f\u53d1\u5e03\u4e4b\u65e5\u5bf9\u672a\u6765\u4e8b\u4ef6\u7684\u5f53\u524d\u89c2\u70b9\u3001\u9884\u6d4b\u3001\u4fe1\u5ff5\u548c\u9884\u671f\u3002\u6b64\u7c7b\u524d\u77bb\u6027\u58f0\u660e\u662f\u57fa\u4e8e\u672c\u96c6\u56e2\u65e0\u6cd5\u63a7\u5236\u7684\u4e00\u4e9b\u5047\u8bbe\u548c\u56e0\u7d20\u3002\u56e0\u6b64\uff0c\u5b83\u4eec\u53d7\u5230\u91cd\u5927\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u4e8b\u4ef6\u6216\u7ed3\u679c\u53ef\u80fd\u4e0e\u8fd9\u4e9b\u524d\u77bb\u6027\u58f0\u660e\u6709\u91cd\u5927\u5dee\u5f02\uff0c\u672c\u65b0\u95fb\u7a3f\u4e2d\u8ba8\u8bba\u7684\u524d\u77bb\u6027\u4e8b\u4ef6\u53ef\u80fd\u4e0d\u4f1a\u53d1\u751f\u3002\u8fd9\u4e9b\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u6211\u4eec\u6700\u8fd1\u7684\u5e74\u5ea6\u62a5\u544a\u548c\u4e2d\u671f\u62a5\u544a\u4ee5\u53ca\u5728\u6211\u4eec\u516c\u53f8\u7f51\u7ad9https:\/\/www.carsgen.com \u4e0a\u53d1\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u62a5\u544a\u4e2d\u300c\u4e3b\u8981\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u300d\u6807\u9898\u4e0b\u7684\u8be6\u7ec6\u5185\u5bb9\u3002\u5bf9\u4e8e\u672c\u65b0\u95fb\u7a3f\u4e2d\u7684\u4efb\u4f55\u9884\u6d4b\u3001\u76ee\u6807\u3001\u4f30\u8ba1\u6216\u9884\u6d4b\u7684\u5b9e\u73b0\u6216\u5408\u7406\u6027\uff0c\u6211\u4eec\u4e0d\u4f5c\u4efb\u4f55\u9648\u8ff0\u6216\u4fdd\u8bc1\uff0c\u4e5f\u4e0d\u5e94\u4f9d\u8d56\u8fd9\u4e9b\u9884\u6d4b\u3002<\/p>\n

\u7f8e\u5fb7\u7eb3\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n

\u672c\u65b0\u95fb\u7a3f\u7684\u524d\u77bb\u6027\u58f0\u660e\u7b26\u54081995\u5e74\u300a\u79c1\u4eba\u8bc1\u5238\u8bc9\u8bbc\u6539\u9769\u6cd5\u6848\u300b\u53ca\u5176\u4fee\u8ba2\u7684\u89c4\u5b9a\uff0c\u5305\u62ec\u7f8e\u5fb7\u7eb3\u8bd5\u9a8c\u6027Claudin18.2 mRNA\u764c\u75c7\u75ab\u82d7\uff0c\u4ee5\u53ca\u7f8e\u5fb7\u7eb3\u4e0e\u79d1\u6d4e\u836f\u4e1a\u5408\u4f5c\u8bc4\u4f30CT041\u4e0emRNA\u764c\u75c7\u75ab\u82d7\u7684\u7ec4\u5408\u6548\u679c\u3002\u8fd9\u4e9b\u98ce\u9669\u3001\u4e0d\u786e\u5b9a\u6027\u548c\u5176\u4ed6\u56e0\u7d20\u5305\u62ec\u7f8e\u5fb7\u7eb3\u5411\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\uff08SEC\uff09\u63d0\u4ea4\u7684\u622a\u81f32022\u5e7412\u670831\u65e5\u8d22\u5e7410-K\u8868\u5e74\u5ea6\u62a5\u544a\u4ee5\u53ca\u7f8e\u5fb7\u7eb3\u968f\u540e\u5411SEC\u63d0\u4ea4\u7684\u6587\u4ef6\u4e2d"\u98ce\u9669\u56e0\u7d20"\u6807\u9898\u4e0b\u63cf\u8ff0\u7684\u5176\u4ed6\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\uff0c\u53ef\u5728\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\u7f51\u7ad9www.SEC.gov\u4e0a\u67e5\u9605\u3002\u9664\u6cd5\u5f8b\u8981\u6c42\u5916\uff0c\u7f8e\u5fb7\u7eb3\u516c\u53f8\u4e0d\u627f\u62c5\u5728\u51fa\u73b0\u65b0\u4fe1\u606f\u3001\u672a\u6765\u53d1\u5c55\u6216\u5176\u4ed6\u60c5\u51b5\u65f6\u66f4\u65b0\u6216\u4fee\u8ba2\u672c\u65b0\u95fb\u7a3f\u4e2d\u4efb\u4f55\u524d\u77bb\u6027\u58f0\u660e\u7684\u4efb\u4f55\u610f\u56fe\u6216\u8d23\u4efb\u3002\u8fd9\u4e9b\u524d\u77bb\u6027\u58f0\u660e\u57fa\u4e8e\u7f8e\u5fb7\u7eb3\u76ee\u524d\u7684\u9884\u671f\uff0c\u4ec5\u4ee3\u8868\u622a\u6b62\u672c\u65b0\u95fb\u7a3f\u53d1\u5e03\u4e4b\u65e5\u7684\u9884\u671f\u3002<\/p>\n

\u8054\u7cfb\u79d1\u6d4e\u836f\u4e1a<\/b><\/p>\n

\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1ahttps:\/\/www.carsgen.com\/<\/a><\/p>\n

\u5a92\u4f53\u8054\u7cfb\uff1aPR@carsgen.com<\/a><\/p>\n

\u8054\u7cfb\u7f8e\u5fb7\u7eb3<\/b><\/p>\n

\u5a92\u4f53\u5173\u7cfb\uff1a<\/p>\n

Luke Mircea-Willats<\/span><\/p>\n

Senior Director, International Communications<\/p>\n

Luke.mirceawillats@modernatx.com<\/a> <\/p>\n

\u6295\u8d44\u8005\u5173\u7cfb\uff1a<\/p>\n

Lavina Talukdar<\/p>\n

Senior Vice President & Head of Investor Relations<\/p>\n

617-209-5834<\/p>\n

Lavina.Talukdar@modernatx.com<\/a><\/p>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

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"CT041\u662f\u76ee\u524d\u5f00\u53d1\u8fdb\u5ea6\u6700\u9886\u5148\u7684\u5b9e\u4f53\u7624CAR-T\u7ec6\u80de\u7597\u6cd5\uff08\u5904\u4e8e\u5173\u952eII\u671f\u4e34\u5e8a\u9636\u6bb5\uff09\uff0c\u5728\u6cbb\u7597\u80c3\u764c\u548c\u80f0\u817a\u764c\u65b9\u9762\u4e00\u76f4\u5448\u73b0\u51fa\u5149\u660e\u7684\u6cbb\u7597\u524d\u666f\u3002\u4e3a\u4e86\u8ffd\u6c42\u2018\u4f7f\u764c\u75c7\u53ef\u6cbb\u6108’\u7684\u76ee\u6807\uff0c\u6211\u4eec\u4e0d\u65ad\u63a2\u7d22\u591a\u79cd\u9014\u5f84\u6765\u6d88\u9664\u80bf\u7624\u3002\u5c06CAR-T\u7ec6\u80de\u7597\u6cd5\u4e0e\u764c\u75c7\u75ab\u82d7\u8054\u5408\u6cbb\u7597\u80bf\u7624\uff0c\u6709\u53ef\u80fd\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u5927\u7684\u4e34\u5e8a\u83b7\u76ca\u3002"\u79d1\u6d4e\u836f\u4e1a\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u3001\u9996\u5e2d\u6267\u884c\u5b98\u3001\u9996\u5e2d\u79d1\u5b66\u5b98\u674e\u5b97\u6d77\u535a\u58eb\u8868\u793a\uff0c"\u7f8e\u5fb7\u7eb3\u516c\u53f8\u5df2\u5728mRNA\u75ab\u82d7\u548c\u6cbb\u7597\u9886\u57df\u786e\u7acb\u4e86\u79d1\u5b66\u548c\u5546\u4e1a\u4e0a\u7684\u9886\u5bfc\u5730\u4f4d\uff0c\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0e\u7f8e\u5fb7\u7eb3\u5408\u4f5c\uff0c\u63a2\u7d22\u53cc\u65b9\u521b\u65b0\u7597\u6cd5\u7684\u8054\u5408\u6cbb\u7597\u6f5c\u529b\u3002"  "\u6211\u4eec\u5f88\u8363\u5e78\u4e0e\u79d1\u6d4e\u836f\u4e1a\u5408\u4f5c\uff0c\u5171\u540c\u63a2\u7d22CAR-T\u4e0e\u8bd5\u9a8c\u6027Claudin18.2 mRNA\u764c\u75c7\u75ab\u82d7\u7684\u6f5c\u5728\u534f\u540c\u4f5c\u7528\u3002Claudin18.2\u4f5c\u4e3a\u4e00\u4e2a\u524d\u666f\u5e7f\u9614\u7684\u6cbb\u7597\u9776\u70b9\uff0c\u6709\u671b\u7528\u4e8e\u6cbb\u7597\u591a\u79cd\u533b\u7597\u9700\u6c42\u8feb\u5207\u7684\u764c\u75c7\u7c7b\u578b\u3002\u6211\u4eec\u5c06\u6301\u7eed\u53d1\u6325mRNA\u79d1\u5b66\u7684\u6f5c\u529b\uff0c\u5728\u80bf\u7624\u9886\u57df\u6253\u9020\u65b0\u4e00\u4ee3\u7684\u9769\u547d\u6027\u836f\u7269\u3002" \u7f8e\u5fb7\u7eb3\u5916\u90e8\u7814\u7a76\u521b\u65b0\u9996\u5e2d\u79d1\u5b66\u5b98Lin Guey\u535a\u58eb\u8868\u793a\u3002 \u5173\u4e8eCT041 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