{"id":92061,"date":"2023-08-18T07:34:00","date_gmt":"2023-08-18T00:34:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023081807340092061"},"modified":"2023-08-18T15:42:32","modified_gmt":"2023-08-18T07:42:32","slug":"%e4%ba%91%e9%a1%b6%e6%96%b0%e8%80%80%e5%90%88%e4%bd%9c%e4%bc%99%e4%bc%b4-calliditas-therapeutics-%e5%ae%a3%e5%b8%83%e4%ba%8e%e5%85%a8%e7%90%83%e9%a1%b6%e7%ba%a7%e5%8c%bb%e5%ad%a6%e6%9c%9f%e5%88%8a","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023081807340092061","title":{"rendered":"\u4e91\u9876\u65b0\u8000\u5408\u4f5c\u4f19\u4f34 Calliditas Therapeutics \u5ba3\u5e03\u4e8e\u5168\u7403\u9876\u7ea7\u533b\u5b66\u671f\u520a\u300a\u67f3\u53f6\u5200\u300b\u53d1\u8868NefIgArd 3 \u671f\u7814\u7a76\u7684\u5b8c\u6574\u7ed3\u679c"},"content":{"rendered":"

\u4e0a\u6d77<\/span>2023\u5e748\u670818\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — 2023 \u5e74 8\u6708 18\u65e5 – \u4e91\u9876\u65b0\u8000\uff08HKEX 1952.HK\uff09\u5408\u4f5c\u4f19\u4f34Calliditas Therapeutics AB \uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aCALT\uff0c\u7eb3\u65af\u8fbe\u514b\u65af\u5fb7\u54e5\u5c14\u6469\u80a1\u7968\u4ee3\u7801\uff1aCALTX\uff09\u5ba3\u5e03\u5728\u5168\u7403\u9876\u7ea7\u533b\u5b66\u671f\u520a\u300a\u67f3\u53f6\u5200\u300b\u4e0a\u53d1\u8868\u7528\u4ee5\u8bc4\u4f30\u8010\u8d4b\u5eb7® \u6cbb\u7597\u6210\u4eba\u539f\u53d1\u6027 IgA \u80be\u75c5 (IgAN) \u7684NefIgArd  3 \u671f\u7814\u7a76\u7684\u5b8c\u6574\u6570\u636e\u3002\u8be53 \u671f\u7814\u7a76\u8fbe\u5230\u4e86\u4e3b\u8981\u7ec8\u70b9\uff0c\u5373\u5728\u4f30\u7b97\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08eGFR\uff09\u4e0a\uff0c\u8010\u8d4b\u5eb7®\u8868\u73b0\u51fa\u6bd4\u5bf9\u7167\u7ec4\u66f4\u663e\u8457\u7684\u80be\u810f\u4fdd\u62a4\u4f5c\u7528\u3002<\/p>\n

\u4e91\u9876\u65b0\u8000\u9996\u5e2d\u6267\u884c\u5b98\u7f57\u6c38\u5e86\u8868\u793a\uff1a"\u5728\u9876\u7ea7\u533b\u5b66\u671f\u520a\u300a\u67f3\u53f6\u5200\u300b\u4e0a\u53d1\u8868\u8010\u8d4b\u5eb7®\u7684\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u51f8\u663e\u4e86\u8fd9\u4e00\u9488\u5bf9\u75be\u75c5\u6e90\u5934\u7684\u9996\u521b\u7597\u6cd5\u7684\u79d1\u5b66\u6027\u53ca\u91cd\u8981\u6027\u3002\u786e\u8bc1\u7684\u957f\u671f eGFR \u83b7\u76ca\u53cd\u6620\u4e86\u8010\u8d4b\u5eb7®\u901a\u8fc7\u9488\u5bf9\u75be\u75c5\u6e90\u5934\u7684\u4f5c\u7528\u673a\u5236\uff0c\u63d0\u4f9b\u4e86\u7279\u5f02\u6027\u7684\u6539\u53d8\u75be\u75c5\u8fdb\u5c55\u7684\u6cbb\u7597\u65b9\u6848<\/span>\uff0c\u4ece\u800c\u8fbe\u5230\u5ef6\u7f13\u80be\u529f\u80fd\u4e0b\u964d\u7684\u6cbb\u7597\u4f5c\u7528\u3002\u4e2d\u56fd\u53c2\u4e0e\u4e86NefIgArd 3\u671f\u7814\u7a76\uff0c\u4e91\u9876\u65b0\u8000\u8ba1\u5212\u5c06\u5728\u672a\u6765\u7684\u5b66\u672f\u4f1a\u8bae\u4e0a\u53d1\u5e03\u8010\u8d4b\u5eb7®\u5728\u4e2d\u56fd\u4e9a\u7ec4\u4eba\u7fa4\u7684\u4e34\u5e8a\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u6211\u4eec\u671f\u5f85\u4eca\u5e74\u4e0b\u534a\u5e74\u83b7\u5f97\u4e2d\u56fd\u836f\u76d1\u5c40\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u6279\u51c6\uff0c\u5c06\u8010\u8d4b\u5eb7® \u5e26\u7ed9\u4e2d\u56fdIgA \u80be\u75c5\u60a3\u8005\uff0c\u4ee5\u6ee1\u8db3\u8feb\u5207\u7684\u4e34\u5e8a\u9700\u6c42\u3002"<\/p>\n

\u8be5\u53d1\u8868\u6587\u7ae0\u7684\u7b2c\u4e00\u4f5c\u8005\u3001\u7f8e\u56fd\u5185\u79d1\u533b\u5e08\u534f\u4f1a\u4f1a\u5458\u3001\u65af\u5766\u798f\u533b\u7597\u4e2d\u5fc3\u7684Richard Lafayette \u533b\u5b66\u535a\u58eb\u8868\u793a<\/span>\uff1a"\u4e24\u5e74\u603b\u659c\u7387\u7684\u652f\u6301\u6027\u5206\u6790\u7ed3\u679c\u4e0d\u4ec5\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\uff0c\u800c\u4e14\u5177\u6709\u4e34\u5e8a\u610f\u4e49\uff0c\u663e\u793a\u51fa\u6301\u4e45\u7684\u6cbb\u7597\u83b7\u76ca\u3002\u5e76\u4e14\u5728\u5168\u4f53\u7814\u7a76\u4eba\u7fa4\u4e2d\u90fd\u89c2\u5bdf\u5230\u4e86eGFR\u7684\u83b7\u76ca\uff0c\u5404\u79cd\u4e0d\u540c\u57fa\u7ebf\u6c34\u5e73\u7684\u5c3f\u86cb\u767d\u808c\u9150\u6bd4(UPCR)\u4eba\u7fa4\u5747\u6709\u83b7\u76ca\u3002\u86cb\u767d\u5c3f\u7684\u6301\u7eed\u4e0b\u964d\u548c\u5bf9\u80be\u529f\u80fd\u7684\u4fdd\u62a4\u4f5c\u7528\u652f\u6301\u8010\u8d4b\u5eb7\u5177\u6709\u6539\u53d8\u75be\u75c5\u8fdb\u5c55\u7684\u4f5c\u7528\u3002\u8fd9\u4e9b\u975e\u5e38\u79ef\u6781\u5b8c\u6574\u7684\u7814\u7a76\u7ed3\u679c\u4e3a\u60a3\u8005\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\uff0c\u5e76\u51f8\u663e\u4e86\u8010\u8d4b\u5eb7\u80fd\u4e3aIgA\u80be\u75c5\u60a3\u8005\u751f\u6d3b\u5e26\u6765\u975e\u51e1\u6709\u610f\u4e49\u6539\u53d8\u7684\u6f5c\u529b\u3002"<\/p>\n

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\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n

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\u603b\u659c\u7387\u7684\u7ec4\u95f4\u5dee\u5f02\u4e3a\u6bcf\u5e742.95 mL\/min\/1.73m2 (p<0·0001)\u3002 \u8010\u8d4b\u5eb7® \u6cbb\u7597\u7ec4\u89c2\u5bdf\u5230\u6301\u4e45\u7684 UPCR\uff08\u5c3f\u86cb\u767d\u4e0e\u808c\u9150\u6bd4\uff09\u4e0b\u964d\u4f5c\u7528\uff0c\u5728\u6cbb\u7597\u671f\u7ed3\u675f\u540e\u7684 15 \u4e2a\u6708\u7684\u505c\u836f\u968f\u8bbf\u671f\u95f4\u4f9d\u7136\u4fdd\u6301\u6301\u4e45\u7684\u6cbb\u7597\u6548\u679c\u3002\u572815\u4e2a\u6708\u7684\u505c\u836f\u968f\u8bbf\u671f\uff0c\u8010\u8d4b\u5eb7® \u6cbb\u7597\u7ec4\u7684UPCR\u4e0b\u964d\u5e45\u5ea6\u5728 30% \u4ee5\u4e0a\uff0c\u5176\u95f4\u5728\u7b2c12 \u4e2a\u6708\u65f6\uff08\u505c\u836f\u540e\u7b2c3\u4e2a\u6708\uff09\u89c2\u5bdf\u5230 UPCR \u4e0b\u964d 50% \u4ee5\u4e0a\u3002 \u8010\u8d4b\u5eb7® \u603b\u4f53\u8010\u53d7\u6027\u826f\u597d\uff0c\u5927\u591a\u6570\u6cbb\u7597\u5f15\u8d77\u7684\u4e0d\u826f\u4e8b\u4ef6 (TEAE)… Read 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