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type=\"disc\">\n<li>\u603b\u6536\u5165\u8fbe\u4eba\u6c11\u5e012.615\u4ebf\u5143\uff0c\u5176\u4e2d\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u9500\u552e\u989d\u4e3a\u4eba\u6c11\u5e012.469\u4ebf\u5143\uff0c\u8212\u683c\u5229\u5355\u6297\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u6536\u5165\u4e3a\u4eba\u6c11\u5e011,462\u4e07\u5143<\/li>\n<li>\u666e\u62c9\u66ff\u5c3c\u83b7\u6388\u4e24\u9879NDA\u6279\u51c6\uff1a\u5728\u4e2d\u56fd\u5927\u9646\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u8f6c\u67d3\u91cd\u6392\uff08RET\uff09\u878d\u5408\u9633\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\uff0c\u4ece\u800c\u4f7f\u666e\u62c9\u66ff\u5c3c\u5728\u4e00\u7ebf\u53ca\u4e8c\u7ebfNSCLC\u7684\u5e94\u7528\u8303\u56f4\u6269\u5927\uff1b\u4ee5\u53ca\u5728\u4e2d\u56fd\u53f0\u6e7e\u7528\u4e8e\u6cbb\u7597RET\u878d\u5408\u9633\u6027NSCLC\u3001RET\u7a81\u53d8\u7684\u7532\u72b6\u817a\u9ad3\u6837\u764c\uff08MTC\uff09\u53caRET\u878d\u5408\u9633\u6027\u7532\u72b6\u817a\u764c\uff08TC\uff09<\/li>\n<li>\u76ee\u524d\u6b63\u5728\u5ba1\u8bc4\u4e2d\u7684\u4e94\u9879NDA\uff1a\u8212\u683c\u5229\u5355\u6297\u5728\u4e2d\u56fd\u5927\u9646\u7528\u4e8e\u590d\u53d1\u6216\u96be\u6cbb\u6027\uff08R\/R\uff09\u7ed3\u5916\u81ea\u7136\u6740\u4f24\u7ec6\u80de\/T\u7ec6\u80de\u6dcb\u5df4\u7624\uff08ENKTL\uff09\uff0c\u8212\u683c\u5229\u5355\u6297\u5728\u82f1\u56fd\u7528\u4e8e\u4e00\u7ebfIV\u671fNSCLC\uff0c\u8212\u683c\u5229\u5355\u6297\u5728\u6b27\u76df\u7528\u4e8e\u4e00\u7ebfIV\u671fNSCLC\u3001\u8212\u683c\u5229\u5355\u6297\u5728\u4e2d\u56fd\u5927\u9646\u7528\u4e8e\u4e00\u7ebf\u80c3\u817a\u764c\/\u80c3\u98df\u7ba1\u7ed3\u5408\u90e8\u817a\u764c\uff08GC\/GEJ\uff09\u4ee5\u53ca\u8212\u683c\u5229\u5355\u6297\u5728\u4e2d\u56fd\u5927\u9646\u7528\u4e8e\u4e00\u7ebf\u98df\u7ba1\u9cde\u764c\uff08ESCC\uff09\u3002\u516c\u53f8\u5df2\u6536\u5230\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u5bf9\u8212\u683c\u5229\u5355\u6297\u4e00\u7ebfIV\u671fNSCLC\u53d1\u51fa\u7684\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u8d28\u91cf\u7ba1\u7406\u89c4\u8303\uff08GCP\uff09\u68c0\u67e5\u901a\u77e5<\/li>\n<li>CS5001 \u56fd\u9645\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u5c55\u8fc5\u901f\uff1a\u4e8e\u7f8e\u56fd\u53ca\u6fb3\u5927\u5229\u4e9a\u8fdb\u884c\u7684CS5001\uff08\u4e00\u79cd\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6837\u5b64\u513f\u53d7\u4f531\uff08ROR1\uff09\u6297\u4f53\u5076\u8054\u836f\u7269\uff08ADC\uff09\u9996\u6b21\u4eba\u4f53\uff08FIH\uff09\u5168\u7403\u8bd5\u9a8c\uff0c\u73b0\u5df2\u6269\u5927\u81f3\u4e2d\u56fd\uff0c\u8fdb\u4e00\u6b65\u52a0\u5feb\u4e86\u8be5\u4ea7\u54c1\u7684\u5f00\u53d1\uff1b\u5242\u91cf\u63a2\u7d22I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u5b8c\u6210\u591a\u4e2a\u5242\u91cf\u6c34\u51c6\u7684\u5b89\u5168\u6027\u8bc4\u4f30\uff0c\u7ed3\u679c\u663e\u793a\u4e86\u826f\u597d\u7684\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027<\/li>\n<li>\u5176\u4ed6\u91cd\u8981\u4e34\u5e8a\u9879\u76ee\u8fdb\u5c55\u987a\u5229\uff1a\u6d1b\u62c9\u66ff\u5c3c\u9488\u5bf9c-ros oncogene 1\uff08ROS1\uff09\u9633\u6027\u665a\u671fNSCLC\u7684\u5173\u952e\u7814\u7a76\u5728\u4e2d\u56fd\u5927\u9646\u5b8c\u6210\u60a3\u8005\u62db\u52df\u4ee5\u53canofazinlimab\u4e0eLENVIMA<sup>&reg; <\/sup>(lenvatinib)\u8054\u5408\u7597\u6cd5\u7528\u4e8e\u4e00\u7ebf\u665a\u671f\u809d\u7ec6\u80de\u764c\uff08HCC\uff09\u7684\u5168\u7403III\u671f\u8bd5\u9a8c\u7684\u4e34\u5e8a\u7814\u7a76\u7a33\u6b65\u63a8\u8fdb<\/li>\n<li>\u4e8e\u5168\u7403\u5b66\u672f\u4f1a\u8bae\uff08\u5982ESMO\u4e16\u754c\u80c3\u80a0\u9053\u80bf\u7624\u5927\u4f1a\uff08ESMO GI\u5927\u4f1a\uff09\u5c55\u793a\u6216\u4e8e\u9876\u5c16\u533b\u5b66\u671f\u520a\uff08\u5982\u300a\u4e34\u5e8a\u80bf\u7624\u5b66\u6742\u5fd7\u300b\u3001\u300aNature Cancer\u300b\uff09\u53d1\u5e03\u516d\u9879\u76f8\u5173\u6570\u636e<\/li>\n<li>\u5f00\u5c55\u8d85\u8fc7\u5341\u4e2a\u53d1\u73b0\u9636\u6bb5\u9879\u76ee\uff0c\u5305\u62ec\u591a\u7279\u5f02\u6027\u6297\u4f53\u3001\u6297\u4f53\u5076\u8054\u836f\u7269\u53ca\u7528\u4e8e\u6cbb\u7597\u96be\u6cbb\u6027\u7ec6\u80de\u5185\u9776\u70b9\u7684\u4e13\u6709\u7ec6\u80de\u7a7f\u900f\u6cbb\u7597\uff08CPT\uff09\u5e73\u53f0\uff1b\u5df2\u83b7\u5f97\u4e09\u79cd\u6cbb\u7597\u65b9\u5f0f\u7684CPT\u4f53\u5916\u6982\u5ff5\u9a8c\u8bc1\uff08PoC\uff09<\/li>\n<li>\u963f\u4f10\u66ff\u5c3c\u7684\u6280\u672f\u8f6c\u79fb\u7533\u8bf7\u6b63\u5728\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08\u56fd\u5bb6\u836f\u76d1\u5c40\uff09\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u7684\u5ba1\u6838\u4e2d\u3002\u666e\u62c9\u66ff\u5c3c\u6280\u672f\u8f6c\u79fb\u6b63\u5728\u987a\u5229\u8fdb\u884c\uff0c\u4e14\u5df2\u542f\u52a8\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76<\/li>\n<\/ul>\n<p><b>I.&nbsp;&nbsp;&nbsp;&nbsp; \u65b0\u9002\u5e94\u75c7\u6210\u529f\u4e0a\u5e02\u53ca\u6301\u7eed\u7a33\u5065\u7684\u5546\u4e1a\u52aa\u529b<\/b><\/p>\n<p>\u622a\u81f3\u672c\u516c\u544a\u65e5\u671f\uff0c\u6211\u4eec\u7684\u5546\u4e1a\u6d3b\u52a8\u6458\u8981\u53ca\u8be6\u60c5\u5982\u4e0b\uff1a<\/p>\n<p>\u2022&nbsp; <b>\u4e0a\u5e02\u4ea7\u54c1\u9500\u91cf\u7a33\u6b65\u63d0\u9ad8<\/b><\/p>\n<p>\u57fa\u4e8e\u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\u3001\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u53ca\u62d3\u8212\u6c83<sup>&reg;<\/sup>\uff08\u827e\u4f0f\u5c3c\u5e03\uff09\u4ea7\u54c1\u603b\u9500\u552e\u989d\u7684\u7a33\u6b65\u589e\u957f\uff0c\u6211\u4eec\u4e8e2023\u5e74\u4e0a\u534a\u5e74\u7684\u603b\u9500\u552e\u51c0\u989d\u4e3a\u4eba\u6c11\u5e012.469\u4ebf\u5143\u3002<\/p>\n<p>\u2022&nbsp; <b>\u65b0\u9002\u5e94\u75c7\u5b9e\u73b0\u6210\u529f\u4e0a\u5e02<\/b><\/p>\n<p>\u6211\u4eec\u6269\u5927\u4e0a\u5e02\u4ea7\u54c1\u7684\u9002\u5e94\u75c7\uff0c\u65e8\u5728\u4e3a\u672a\u6765\u8d21\u732e\u7a33\u5b9a\u7684\u6536\u76ca\u3002<\/p>\n<p>&#8211;&nbsp; \u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\uff1a\u4e00\u7ebf\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027RET\u878d\u5408\u9633\u6027 NSCLC\u60a3\u8005\u7684\u9002\u5e94\u75c7\u4e8e\u4e2d\u56fd\u5927\u9646\u4e0a\u5e02\u3002<\/p>\n<p>&#8211;&nbsp; \u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\uff1a\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027RET\u878d\u5408\u9633\u6027NSCLC\u3001\u665a\u671f\u6216\u8f6c\u79fb\u6027RET\u7a81\u53d8MTC\u53caRET\u878d\u5408\u9633\u6027TC\u60a3\u8005\u7684\u9002\u5e94\u75c7\u4e8e\u4e2d\u56fd\u53f0\u6e7e\u4e0a\u5e02\u3002<\/p>\n<p>\u2022&nbsp; <b>\u6269\u5927\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u5728\u4e3b\u8981\u5e02\u573a\u7684\u9500\u552e\u961f\u4f0d\u8986\u76d6\u8303\u56f4<\/b><\/p>\n<p>\u6211\u4eec\u5c24\u4e3a\u6ce8\u91cd\u786e\u4fdd\u9500\u552e\u56e2\u961f\u7684\u8986\u76d6\u8303\u56f4\uff0c\u622a\u81f3\u672c\u516c\u544a\u65e5\u671f\uff0c\u6211\u4eec\u7684\u8986\u76d6\u8303\u56f4\u5df2\u4ece2022\u5e74\u7684800 \u5bb6\u533b\u9662\u6210\u529f\u6269\u5f20\u81f3\u903e180\u4e2a\u57ce\u5e02\u7684\u7ea6850\u5bb6\uff0c\u5360\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u76f8\u5173\u5e02\u573a\u7684\u7ea675%\u81f380%\uff0c\u6211\u4eec\u76f8\u4fe1\u6211\u4eec\u80fd\u591f\u6700\u5927\u7a0b\u5ea6\u5730\u63d0\u9ad8\u6211\u4eec\u7684\u9500\u552e\u56de\u62a5\u7387\u3002<\/p>\n<p>\u2022&nbsp; <b>\u4e0e\u5173\u952e\u5229\u76ca\u76f8\u5173\u8005\u5f62\u6210\u7cbe\u51c6\u8bca\u65ad\u751f\u6001\u7cfb\u7edf\uff0c\u4fc3\u8fdb\u60a3\u8005\u8bc6\u522b<\/b><\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u5df2\u4e0e\u9876\u5c16\u57fa\u56e0\u6d4b\u5e8f\u516c\u53f8\u7b7e\u7f72\u5408\u4f5c\u534f\u8bae\uff0c\u4ee5\u8fdb\u4e00\u6b65\u63d0\u5347\u5bf9RET\u7a81\u53d8\u7684NSCLC\/TC\u3001\u80c3\u80a0\u9053\u95f4\u8d28\u7624\uff08GIST\uff09\u4e2d\u7684\u8840\u5c0f\u677f\u884d\u751f\u751f\u957f\u56e0\u5b50\u53d7\u4f53\u03b1\uff08PDGFRA\uff09\u5916\u663e\u5b5018\u7a81\u53d8\u53ca\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u91761\uff08IDH1\uff09\u7a81\u53d8\u7684\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08AML\uff09\u7684\u68c0\u6d4b\u7387\u3002\u6211\u4eec\u4ea6\u4e0e\u9876\u7ea7\u533b\u836f\u516c\u53f8\uff08\u5305\u62ec\u767e\u6d4e\u795e\u5dde\u53ca\u9ed8\u514b\uff09\u5efa\u7acb\u80ba\u764c\u7cbe\u51c6\u8bca\u7597\u8054\u76df\uff08LCPA\uff0c\u8be5\u8054\u76df\u662f\u4e1a\u754c\u9996\u4e2a\u4e13\u6ce8\u4e8eNSCLC\u9886\u57df\u7f55\u89c1\u9776\u70b9\u7684\u8054\u76df\uff09\uff0c\u4ee5\u5728\u66f4\u5e7f\u9614\u7684\u5e02\u573a\u6700\u5927\u5316RET\u68c0\u6d4b\u7387\u3002<\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u5df2\u52a0\u5f3a\u4e0e\u56fd\u5bb6\u75c5\u7406\u8d28\u63a7\u4e2d\u5fc3\uff08PQCC\uff09\u7684\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\uff0c\u4ee5\u6807\u51c6\u5316\u68c0\u6d4b\u6d41\u7a0b\u5e76\u63d0\u9ad8\u68c0\u6d4b\u51c6\u786e\u6027\uff0c\u53c2\u4e0e\u533b\u9662\u7684\u6570\u91cf\u6301\u7eed\u589e\u52a0\u3002<\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u5df2\u7ee7\u7eed\u4e3a\u63a5\u53d7RET\u7a81\u53d8\u68c0\u6d4b\u7684NSCLC\/MTC\u60a3\u8005\u53ca\u63a5\u53d7IDH1\u7a81\u53d8\u68c0\u6d4b\u7684AML\u60a3\u8005\u63d0\u4f9b\u8d22\u52a1\u652f\u6301\uff0c\u81ea\u9879\u76ee\u542f\u52a8\u4ee5\u6765\u8986\u76d6\u4e86\u7ea61,200\u540d\u60a3\u8005\u3002<\/p>\n<p>\u2022&nbsp; <b>\u5efa\u7acb\u5e7f\u6cdb\u7684\u884c\u4e1a\u548c\u5b66\u672f\u8ba4\u77e5\u5ea6\uff0c\u6811\u7acb\u54c1\u724c\u548c\u79d1\u5b66\u9886\u5bfc\u529b<\/b><\/p>\n<p>&#8211;&nbsp; \u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\u3001\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u53ca\u62d3\u8212\u6c83<sup>&reg;<\/sup>\uff08\u827e\u4f0f\u5c3c\u5e03\uff09\u5df2\u7eb3\u516521\u9879\u4e2d\u56fd\u56fd\u5bb6\u6307\u5357\uff0c\u7528\u4e8e\u591a\u4e2a\u6cbb\u7597\u9886\u57df\u7684\u68c0\u6d4b\u53ca\u6cbb\u7597\uff0c\u6bd4\u5982NSCLC\u3001TC\u3001GIST\u3001SM\u53caAML\u7b49\u3002\u7279\u522b\u662f\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a(CSCO)\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u8bca\u7597\u6307\u5357\uff082023\u5e74\u7248\uff09\u3001CSCO\u80c3\u80a0\u9053\u95f4\u8d28\u7624\u8bca\u7597\u6307\u5357\uff082022\u5e74\u7248\uff09\u3001\u4e2d\u56fd\u6210\u4eba\u7cfb\u7edf\u6027\u80a5\u5927\u7ec6\u80de\u589e\u591a\u75c7\u8bca\u7597\u6307\u5357\uff082022\u5e74\u7248\uff09\u53ca\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\uff08CACA\uff09\u8840\u6db2\u80bf\u7624\u6307\u5357\uff082022\u5e74\u7248\uff09\u7b49\u3002<\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u4e0e\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u3001CACA\u3001\u4e2d\u534e\u533b\u5b66\u4f1a\u53ca\u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u7b49\u591a\u4e2a\u884c\u4e1a\u534f\u4f1a\u5c31GIST\u3001NSCLC\u3001MTC\u53ca\u6076\u6027\u8840\u6db2\u80bf\u7624\u7684\u8bca\u65ad\u53ca\u6cbb\u7597\u6807\u51c6\u5316\u9879\u76ee\u5c55\u5f00\u5bc6\u5207\u5408\u4f5c\uff0c\u8fdb\u4e00\u6b65\u52a0\u5f3a\u6211\u4eec\u7684\u884c\u4e1a\u8054\u7cfb\u5e76\u5c55\u793a\u6211\u4eec\u7684\u4e13\u4e1a\u80fd\u529b\u3002<\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u53d1\u8d77\u6216\u652f\u6301\u7814\u7a76\u8005\u5f00\u5c55\u836f\u7269\u83b7\u6279\u540e\u7684\u4e34\u5e8a\u9879\u76ee\uff0c\u5982\u7814\u7a76\u8005\u53d1\u8d77\u7684\u8bd5\u9a8c\uff08IIT\uff09\u548c\u771f\u5b9e\u4e16\u754c\u7684\u7814\u7a76\uff08RWS\uff09\uff0c\u4ee5\u4e8e\u591a\u4e2a\u764c\u75c7\u9002\u5e94\u75c7\u4e2d\u751f\u6210\u66f4\u591a\u6570\u636e\u3002\u4f8b\u5982\uff0c\u4e00\u9879\u591a\u4e2d\u5fc3RWS\u8bc4\u4f30\u4e86\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u5728\u4e2d\u56fdGIST\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u53ca\u7597\u6548\uff1b\u53e6\u4e00\u9879IIT\u65e8\u5728\u7814\u7a76\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u5bf9\u4e8e\u6cbb\u7597\u643a\u5e26\u6709KIT D816 \u6216N822\u7a81\u53d8\u7684R\/R AML\u60a3\u8005\u7684\u7597\u6548\u53ca\u5b89\u5168\u6027\u3002<\/p>\n<p><b>\u2022<\/b>&nbsp;<b>\u5236\u5b9a\u4e00\u7cfb\u5217\u65b9\u6cd5\uff0c\u63d0\u9ad8\u6211\u4eec\u836f\u54c1\u7684\u53ef\u53ca\u6027\u53ca\u53ef\u8d1f\u62c5\u6027<\/b><\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u5df2\u66f4\u65b0\u4e0a\u5e02\u4ea7\u54c1\u7684\u5b9a\u4ef7\u7b56\u7565\u3002\u5177\u4f53\u800c\u8a00\uff0c\u66f4\u65b0\u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\u60a3\u8005\u63f4\u52a9\u9879\u76ee\uff08PAP\uff09\u8ba1\u5212\u4ee5\u4e3a\u4e00\u4e9b\u652f\u4ed8\u80fd\u529b\u4f4e\u7684\u60a3\u8005\u964d\u4f4e\u95e8\u69db\u5e76\u63d0\u5347\u4ef7\u683c\u7ade\u4e89\u529b\u3002\u6211\u4eec\u4ea6\u542f\u52a8\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u7684\u65b0PAP\u4e3aGIST\u60a3\u8005\u7684\u957f\u671f\u6cbb\u7597\u63d0\u4f9b\u652f\u63f4\u3002\u6211\u4eec\u8c03\u6574\u62d3\u8212\u6c83<sup>&reg;<\/sup>\uff08\u827e\u4f0f\u5c3c\u5e03\uff09\u7684PAP\u8ba1\u5212\uff0c\u4ee5\u63d0\u9ad8\u53ef\u8d1f\u62c5\u6027\u5e76\u5ef6\u957f\u6cbb\u7597\u6301\u7eed\u65f6\u95f4\uff08DOT\uff09\u3002<\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u786e\u4fdd\u5c06\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u3001\u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\u53ca\u62d3\u8212\u6c83<sup>&reg;<\/sup>\uff08\u827e\u4f0f\u5c3c\u5e03\uff09\u7eb3\u5165\u6240\u6709\u4e3b\u8981\u5730\u533a\uff08\u6bd4\u5982\u5317\u4eac\u3001\u4e0a\u6d77\u3001\u5e7f\u4e1c\u3001\u6d59\u6c5f\u53ca\u5c71\u4e1c\u7b49\uff09\u7684138\u4e2a\u4e3b\u8981\u5546\u4e1a\u53ca\u653f\u5e9c\u4fdd\u9669\u8ba1\u5212\uff0c\u8986\u76d6\u4eba\u53e3\u6570\u7ea61\u4ebf\u3002<\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u7ee7\u7eed\u4e0e\u56fd\u836f\u63a7\u80a1\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u56fd\u836f\u63a7\u80a1\uff09\u8fdb\u884c\u6218\u7565\u5408\u4f5c\uff0c\u5e76\u4e0e\u4e0a\u6d77\u533b\u836f\u96c6\u56e2\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u4e0a\u6d77\u533b\u836f\uff09\u5efa\u7acb\u65b0\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\uff0c\u4ee5\u6269\u5927\u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\u3001\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u53ca\u62d3\u8212\u6c83<sup>&reg;<\/sup>\uff08\u827e\u4f0f\u5c3c\u5e03\uff09\u4e8e\u533b\u9662\u53ca\u836f\u5e97\u7684\u5206\u9500\u8303\u56f4\u3002\u622a\u81f3\u672c\u516c\u544a\u65e5\u671f\uff0c\u6cf0\u5409\u534e<sup>&reg;<\/sup>\uff08\u963f\u4f10\u66ff\u5c3c\uff09\u3001\u666e\u5409\u534e<sup>&reg;<\/sup>\uff08\u666e\u62c9\u66ff\u5c3c\uff09\u53ca\u62d3\u8212\u6c83<sup>&reg;<\/sup>\uff08\u827e\u4f0f\u5c3c\u5e03\uff09\u5df2\u5b8c\u6210\u7ea6300\u5bb6\u533b\u9662\u53ca\u76f4\u8fbe\u60a3\u8005\u4e13\u4e1a\u836f\u623f\uff08DTP\uff09\u5217\u540d\uff0c\u8f832022\u5e74\u7684\u7ea6220\u5bb6\u8fdb\u4e00\u6b65\u63d0\u5347\u3002<\/p>\n<p><b>\u2022<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u5bf9\u60a3\u8005\u8fdb\u884c\u6301\u7eed\u6559\u80b2\u53ca\u652f\u6301\u4ee5\u63d0\u9ad8\u4f9d\u4ece\u53caDOT<\/b><\/p>\n<p>\u6211\u4eec\u901a\u8fc7\u7ebf\u4e0a\u60a3\u8005\u793e\u533a\u53ca\u7ebf\u4e0b\u6559\u80b2\u6d3b\u52a8\u4e0d\u65ad\u52aa\u529b\u4e3a\u60a3\u8005\u63d0\u4f9b\u652f\u6301\uff0c\u4ee5\u63d0\u9ad8\u60a3\u8005\u4f9d\u4ece\u6027\u53caDOT\u3002\u622a\u81f3\u672c\u516c\u544a\u65e5\u671f\uff0c\u6211\u4eec\u7684\u7ebf\u4e0a\u5e73\u53f0\u62e5\u6709\u903e8,000\u540d\u8ba2\u9605\u8005\uff0c\u5e76\u5df2\u81ea\u542f\u52a8\u65f6\u53d1\u5e03\u8d85\u8fc7330\u4e2a\u60a3\u8005\u6545\u4e8b\u53ca\u8d44\u8baf\u3002\u6211\u4eec\u5df2\u4e3e\u529e\u7ea6200\u6b21\u60a3\u8005\u6559\u80b2\u6d3b\u52a8\uff0c\u8986\u76d620,000\u540d\u6f5c\u5728\u60a3\u8005\u3002<\/p>\n<p><b>\u2022<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u4e0e\u8f89\u745e\u5c31\u8212\u683c\u5229\u5355\u6297\u5728\u4e2d\u56fd\u7684\u5546\u4e1a\u5316\u8fdb\u884c\u5408\u4f5c<\/b><\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u6b63\u4e0e\u5408\u4f5c\u4f19\u4f34\u8f89\u745e\u5c55\u5f00\u5bc6\u5207\u5408\u4f5c\uff0c\u4ee5\u63a8\u8fdb\u8212\u683c\u5229\u5355\u6297\u5728\u4e2d\u56fd\u5927\u9646\u7684\u5546\u4e1a\u5316\u3002<\/p>\n<p>&#8211;&nbsp; \u57282023\u5e74\uff0c\u8212\u683c\u5229\u5355\u6297\u6cbb\u7597III\u671fNSCLC\u5728CSCO\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u6cbb\u7597\u6307\u5357\uff082023\u5e74\u7248\uff09\u53caCSCO\u514d\u75ab\u6cbb\u7597\u6307\u5357\uff082023\u5e74\u7248\uff09\u4e2d\u5df2\u5347\u7ea7\u81f31\u7ea7\u63a8\u8350\u3002\u6b64\u5916\uff0c\u8212\u683c\u5229\u5355\u6297\u4ea6\u83b7\u7eb3\u5165\u4e2d\u56fdIV\u671f\u539f\u53d1\u6027\u80ba\u764c\u4e34\u5e8a\u5b9e\u8df5\u6307\u5357\uff082023\u5e74\u7248\uff09\u3002<\/p>\n<p><b>II.&nbsp;&nbsp;&nbsp; \u4e0d\u65ad\u53d1\u5c55\u7684\u7ba1\u7ebf\u7684\u4e34\u5e8a\u8fdb\u5c55<\/b><\/p>\n<p>\u8be6\u60c5\u5982\u4e0b\uff1a<\/p>\n<p><b>\u2022<\/b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b>\u8212\u683c\u5229\u5355\u6297<\/b>\uff08CS1001\uff0cPD-L1\u6297\u4f53\uff09\uff0c\u65b0\u9002\u5e94\u75c7\u6b63\u5728\u5ba1\u8bc4\u4e2d\u5e76\u6b63\u6269\u5c55\u81f3\u6b27\u6d32\u53ca\u82f1\u56fd\u3002<\/p>\n<p>&#8211;&nbsp; <b>IV\u671fNSCLC\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li>\u5728\u5927\u4e2d\u534e\u533a\u4ee5\u5916\u7684\u5e02\u573a\uff0cIV\u671fNSCLC\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\uff08MAA\uff09\u6b63\u5728\u591a\u4e2a\u56fd\u5bb6\u53ca\u5730\u533a\u7684\u76d1\u7ba1\u673a\u6784\u5ba1\u8bc4\u30022023\u5e742\u6708\u53ca2022\u5e7412\u6708\uff0c\u8212\u683c\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u8f6c\u79fb\u6027NSCLC\u60a3\u8005\u7684MAA\u83b7EMA\u53ca\u82f1\u56fd\u836f\u54c1\u548c\u533b\u7597\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\uff08MHRA\uff09\u53d7\u7406\u3002\u76ee\u524d\uff0c\u6b64\u9002\u5e94\u75c7\u6b63\u5728\u53cc\u65b9\u5ba1\u8bc4\u4e2d\u30022023\u5e747\u6708\uff0c\u6211\u4eec\u6536\u5230\u6765\u81ea\u6b27\u76dfEMA\u5c31\u6b64\u9002\u5e94\u75c7\u8fdb\u884cGCP\u68c0\u67e5\u7684\u901a\u77e5\u3002<\/li>\n<li>2023\u5e746\u6708\uff0c\u6211\u4eec\u5ba3\u5e03IV\u671fNSCLC\u60a3\u8005\u7684\u6ce8\u518c\u6027GEMSTONE-302\u7814\u7a76\u7684\u603b\u751f\u5b58\u671f\u671f\u4e2d\u5206\u6790\u7ed3\u679c\u5df2\u5728\u4e16\u754c\u77e5\u540d\u7684\u80bf\u7624\u5b66\u671f\u520a\uff0d\u300aNature Cancer\u300b\u4e0a\u53d1\u5e03\u3002<\/li>\n<\/ul>\n<p>&#8211;&nbsp; <b>GC\/GEJ\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li>2023\u5e742\u6708\uff0c\u8212\u683c\u5229\u5355\u6297\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027GC\/GEJ\u60a3\u8005\u7684NDA\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\u3002<\/li>\n<\/ul>\n<p>&#8211;&nbsp; <b>ESCC\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li>2023\u5e744\u6708\uff0c\u8212\u683c\u5229\u5355\u6297\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u590d\u53d1\u6216\u8f6c\u79fb\u6027ESCC\u60a3\u8005\u7684NDA\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\u3002<\/li>\n<li>2023\u5e741\u6708\uff0c\u6211\u4eec\u5ba3\u5e03\u8212\u683c\u5229\u5355\u6297\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u590d\u53d1\u6216\u8f6c\u79fb\u6027ESCC\u7684GEMSTONE-304\u7814\u7a76\u8fbe\u5230\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u3002\u4e0e\u5b89\u6170\u5242\u8054\u5408\u5316\u7597\u76f8\u6bd4\uff0c\u8212\u683c\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u660e\u663e\u6539\u5584PFS\u548cOS\uff0c\u5dee\u5f02\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u4e0e\u4e34\u5e8a\u610f\u4e49\u3002\u8be5\u7814\u7a76\u7684\u8be6\u7ec6\u6570\u636e\u5df2\u4e8e2023\u5e746\u6708\u5728ESMO GI\u5927\u4f1a\u4e0a\u8fdb\u884c\u4e86\u516c\u5e03\u3002<\/li>\n<\/ul>\n<p>&#8211;&nbsp; <b>R\/R ENKTL\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li>2023\u5e743\u6708\uff0cR\/R ENKTL\u60a3\u8005\u7684\u6ce8\u518c\u6027GEMSTONE-201\u7814\u7a76\u7684\u7ed3\u679c\u53d1\u5e03\u4e8e\u9876\u7ea7\u80bf\u7624\u5b66\u671f\u520a\uff0d\u300a\u4e34\u5e8a\u80bf\u7624\u5b66\u6742\u5fd7\u300b\u3002<\/li>\n<\/ul>\n<p><b>\u2022<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u666e\u62c9\u66ff\u5c3c\uff08CS3009\uff0cRET\u6291\u5236\u5242\uff09<\/b><\/p>\n<p>&#8211;&nbsp; 2023\u5e741\u6708\uff0c\u4e2d\u56fd\u53f0\u6e7e\u98df\u54c1\u836f\u7269\u7ba1\u7406\u7f72\uff08TFDA\uff09\u6279\u51c6\u5176\u7528\u4e8e\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027RET\u878d\u5408\u9633\u6027NSCLC\u3001\u665a\u671f\u6216\u8f6c\u79fb\u6027RET\u7a81\u53d8MTC\u53caRET\u878d\u5408\u9633\u6027TC\u60a3\u8005\u7684NDA\u3002<\/p>\n<p>&#8211;&nbsp; 2023\u5e746\u6708\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u5176\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u5148\u524d\u672a\u63a5\u53d7\u7cfb\u7edf\u6cbb\u7597\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027RET\u878d\u5408\u9633\u6027NSCLC\u60a3\u8005\u7684\u6269\u5c55\u9002\u5e94\u75c7\u3002<\/p>\n<p>&#8211;&nbsp; 2023\u5e746\u6708\uff0cRET\u878d\u5408\u9633\u6027NSCLC\u4e2d\u56fd\u60a3\u8005\u7684I\/II\u671f ARROW\u8bd5\u9a8c\u7684\u6700\u65b0\u7ed3\u679c\u53d1\u8868\u4e8e\u300aCancer\u300b\u3002<\/p>\n<p><b>\u2022<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CS5001 (LCB71\u3001ROR1 ADC)<\/b><\/p>\n<p>&#8211;&nbsp; \u672c\u6f5c\u5728\u540c\u7c7b\u6700\u4f18\uff08BIC\uff09ROR1 ADC\u7684FIH\u5168\u7403\u8bd5\u9a8c\u7684\u5242\u91cf\u9012\u589e\u90e8\u5206\u5df2\u8fc5\u901f\u63a8\u8fdb\u5230\u7f8e\u56fd\u53ca\u6fb3\u5927\u5229\u4e9a\u5242\u91cf\u9012\u589e\u90e8\u5206\u7684\u60a3\u8005\u62db\u52df\u9636\u6bb5\uff0c\u5e76\u663e\u793a\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027\u3002\u6b64\u56fd\u9645\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u76ee\u524d\u5df2\u6269\u5c55\u81f3\u5305\u62ec\u4e2d\u56fd\uff0c\u4ece\u800c\u8fdb\u4e00\u6b65\u52a0\u901f\u8be5\u4ea7\u54c1\u7684\u5f00\u53d1\u3002\u4f5c\u4e3a\u4e34\u5e8a\u5f00\u53d1\u4e2d\u8fdb\u5c55\u6700\u5feb\u7684ROR1 ADC\u4e4b\u4e00\uff0cCS5001\u5bf9\u4e8e\u5404\u79cd\u6076\u6027\u8840\u6db2\u53ca\u5b9e\u4f53\u80bf\u7624\u6709\u6cbb\u7597\u6f5c\u529b\u3002<\/p>\n<p>&#8211;&nbsp; CS5001\u6709\u8bb8\u591a\u5dee\u5f02\u6027\u7279\u5f81\uff0c\u5305\u62ec\u4e13\u6709\u7684\u4f4d\u70b9\u7279\u5f02\u6027\u5076\u8054\u3001\u80bf\u7624\u9009\u62e9\u6027\u53ef\u5207\u5272\u8fde\u63a5\u5b50\u53ca\u524d\u836f\u6280\u672f\u3002\u4e0e\u53c2\u6bd4ROR1 ADC\u76f8\u6bd4\u8f83\uff0cCS5001\u5df2\u4e8e\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\u53ca\u4e09\u9634\u6027\u4e73\u817a\u764c\u5f02\u79cd\u79fb\u690d\u6a21\u578b\u663e\u793a\u51faBIC\u6f5c\u529b\u3002\u6b64\u5916\uff0cCS5001\u5728\u4f53\u5916\u5171\u57f9\u517b\u7cfb\u7edf\u663e\u793a\u51fa\u65c1\u89c2\u8005\u6548\u5e94\uff0c\u8868\u660eROR1\u5f02\u8d28\u6027\/\u4f4e\u8868\u8fbe\u7684\u5b9e\u4f53\u7624\u4ea6\u53ef\u80fd\u53d7\u76ca\u30022023\u5e743\u6708\uff0c\u6211\u4eec\u4e8e\u7b2c13 \u5c4a\u4e16\u754c ADC\u4f26\u6566\u5927\u4f1a\uff08\u4e16\u754c ADC \u4f26\u6566\uff09\u4e0a\u4ee5\u53e3\u5934\u6c47\u62a5\u5f62\u5f0f\u5c55\u793aCS5001\u7684\u8f6c\u5316\u6570\u636e\u3002<\/p>\n<p>&#8211;&nbsp; \u6b64\u5916\uff0c\u4e3a\u786e\u4fdd\u751f\u7269\u6807\u8bb0\u7269\u9a71\u52a8\u60a3\u8005\u7684\u9009\u62e9\u4e43\u57fa\u4e8e\u80bf\u7624ROR1\u8868\u8fbe\uff0c\u6211\u4eec\u5df2\u8bc6\u522b\u6709\u6f5c\u529b\u7684\u5019\u9009ROR1\u6297\u4f53\u514b\u9686\u7528\u4e8e\u514d\u75ab\u7ec4\u5316\uff08IHC\uff09\uff0c\u4ee5\u652f\u6301\u672a\u6765\u6709\u5173\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u7684\u5de5\u4f5c\u3002<\/p>\n<p><b>\u2022<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp; \u827e\u4f0f\u5c3c\u5e03\uff08CS3010\uff0cIDH1\u6291\u5236\u5242\uff09<\/b><\/p>\n<p>&#8211;&nbsp; 2023\u5e741\u6708\uff0c\u6211\u4eec\u5b8c\u6210\u4e86\u827e\u4f0f\u5c3c\u5e03\u5728R\/R AML\u60a3\u8005\u7684\u4e2d\u56fd\u6865\u63a5\u7814\u7a76\u3002<\/p>\n<p>&#8211;&nbsp; 2023\u5e745\u6708\uff0c\u6211\u4eec\u4e0eCDE\u5c31\u827e\u4f0f\u5c3c\u5e03\u7528\u4e8eR\/R AML\u7684\u5b8c\u5168\u6279\u51c6\u7684\u76d1\u7ba1\u9014\u5f84\u8fbe\u6210\u4e00\u81f4\u4e14\u6b63\u5728\u51c6\u5907\u7533\u8bf7\u6750\u6599\u3002<\/p>\n<p><b>\u2022<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u963f\u4f10\u66ff\u5c3c\uff08CS3007\uff0cKIT\/PDGFRA\u6291\u5236\u5242\uff09<\/b><\/p>\n<p>&#8211;&nbsp; 2023\u5e745\u6708\uff0c\u6211\u4eec\u7684\u5408\u4f5c\u4f19\u4f34Blueprint Medicines\u5c31\u8be5\u4ea7\u54c1\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u60f0\u6027\u7cfb\u7edf\u6027\u80a5\u5927\u7ec6\u80de\u589e\u591a\u75c7\u53d6\u5f97\u6765\u81ea\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u7684NDA\u6279\u51c6\u3002<\/p>\n<p>&#8211;&nbsp; 2023\u5e746\u6708\uff0c\u6211\u4eec\u4e8e2023\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u4e86\u963f\u4f10\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u80a0\u9053\u95f4\u8d28\u7624\u60a3\u8005\u7684\u65b0\u6570\u636e\u3002<\/p>\n<p><b>\u2022<\/b>&nbsp;<b>\u6d1b\u62c9\u66ff\u5c3c\uff08<\/b><b>ALK\/ROS-1\u6291\u5236\u5242\uff09<\/b><\/p>\n<p>&#8211;&nbsp; \u6211\u4eec\u6b63\u4e0e\u8f89\u745e\u5408\u4f5c\u5728\u5927\u4e2d\u534e\u533a\u8054\u5408\u5f00\u53d1\u6d1b\u62c9\u66ff\u5c3c\uff0c\u5e76\u9488\u5bf9ROS1\u9633\u6027\u665a\u671fNSCLC\u60a3\u8005\u8fdb\u884c\u5173\u952e\u7814\u7a76\u30022023\u5e746\u6708\uff0c\u6211\u4eec\u5c31\u8be5\u9879\u7814\u7a76\u5b8c\u6210\u4e86\u60a3\u8005\u5165\u7ec4\u3002<\/p>\n<p><b>III.&nbsp; \u5229\u7528\u591a\u79cd\u521b\u65b0\u6e20\u9053\u5efa\u7acb\u7814\u7a76\u7ba1\u7ebf<\/b><\/p>\n<p>\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u53ca\u514d\u75ab\u80bf\u7624\u836f\u7269\u8054\u5408\u6cbb\u7597\u4ecd\u7136\u662f\u6211\u4eec\u7684\u6218\u7565\u91cd\u70b9\u3002\u5c06\u7ec6\u80de\u6bd2\u6027\u836f\u7269\u7cbe\u786e\u5730\u8f93\u9001\u5230\u80bf\u7624\u7684\u6297\u4f53\u5076\u8054\u836f\u7269\uff0c\u4ee5\u53ca\u53ef\u521b\u9020\u65b0\u751f\u7269\u5b66\u4e14\u81ea\u8eab\u7ec4\u5408\u7684\u591a\u7279\u5f02\u6027\u751f\u7269\u5236\u54c1\u4ee3\u8868\u4e24\u79cd\u65e9\u671f\u5f00\u53d1\u7684\u77ed\u671f\u6a21\u5f0f\u3002<\/p>\n<p>2023\u5e74\u4e0a\u534a\u5e74\uff0c\u6211\u4eec\u5df2\u901a\u8fc7\u82e5\u5e72\u4e3e\u63aa\u53d6\u5f97\u91cd\u5927\u8fdb\u5c55\uff1a<\/p>\n<ul type=\"disc\">\n<li><b>\u540c\u7c7b\u9996\u521b\uff08<\/b><b>FIC\uff09ADCs\uff1a<\/b>\u4e24\u9879\u540c\u7c7b\u9996\u521bADC\u9879\u76ee\u6b63\u5728\u5411\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269\uff08PCC\uff09\u9636\u6bb5\u63a8\u8fdb\uff0c\u5176\u4e2d\u5305\u62ec\u91c7\u7528\u5185\u90e8\u673a\u5668\u5b66\u4e60\u751f\u7269\u4fe1\u606f\u7b97\u6cd5\u786e\u5b9a\u4e00\u79cd\u65b0\u578b\u80bf\u7624\u76f8\u5173\u6297\u539f\uff0c\u8be5\u6297\u539f\u5728\u591a\u79cd\u5927\u578b\u80bf\u7624\u9002\u5e94\u75c7\u4e2d\u5747\u6709\u8868\u8fbe\u3002\u540c\u65f6\u5019\u9009\u6297\u4f53\u5df2\u9009\u5b9a\uff0c\u5e76\u4e14\u5171\u8f6d\u5148\u5bfc\u5206\u5b50\u5c55\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u4f53\u5916\u6548\u529b\u53ca\u4f53\u5185\u7597\u6548\u3002\u9884\u671f\u5c06\u4e8e2024\u5e74\u62162025\u5e74\u63d0\u4ea4\u4e34\u5e8a\u7814\u7a76\u7528\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08IND\uff09\u3002<\/li>\n<li><b>\u514d\u75ab\u80bf\u7624\u591a\u7279\u5f02\u6027\u6297\u4f53\uff1a<\/b>&nbsp;CS2009\u4e3a\u9488\u5bf9PD-1\u3001VEGF\u52a0\u53e6\u4e00\u4e2a\u514d\u75ab\u80bf\u7624\u9776\u70b9\u7684\u4e09\u7279\u5f02\u6027\u5206\u5b50\uff0c\u6b63\u5904\u4e8e\u7ec6\u80de\u682a\u5f00\u53d1\u9636\u6bb5\u3002\u9884\u8ba1\u5c06\u57282024\u5e74\u63d0\u4ea4IND\u3002\u6b64\u5916\uff0c\u53e6\u4e24\u9879\u514d\u75ab\u80bf\u7624\u591a\u7279\u5f02\u6027\u9879\u76ee\u6b63\u5206\u522b\u5904\u4e8eIND\u7533\u62a5\u8bd5\u9a8c\u9636\u6bb5\u53caPCC\u7504\u9009\u9636\u6bb5\u3002<\/li>\n<li><b>\u7ec6\u80de\u7a7f\u900f\u6cbb\u7597\u5e73\u53f0\uff1a<\/b>\u8bb8\u591a\u4f17\u6240\u5468\u77e5\u7684\u80bf\u7624\u5b66\u9776\u70b9\u662f\u76ee\u524d\u7684\u6cbb\u7597\u65b9\u6cd5\u8ba4\u4e3a\u4e0d\u53ef\u6210\u836f\u7684\u7ec6\u80de\u5185\u86cb\u767d\u3002\u6211\u4eec\u6b63\u5728\u9488\u5bf9\u8be5\u7b49\u96be\u6cbb\u6027\u9776\u70b9\u5f00\u53d1\u4e00\u79cd\u4e13\u6709\u7684\u7ec6\u80de\u7a7f\u900f\u6cbb\u7597\u5e73\u53f0\u3002\u8be5\u5e73\u53f0\u7684\u5f00\u53d1\u5df2\u53d6\u5f97\u91cd\u5927\u8fdb\u5c55\uff0c\u5177\u6709\u5e7f\u6cdb\u7684\u9488\u5bf9\u80bf\u7624\u53ca\u5176\u4ed6\u75be\u75c5\u7684\u6cbb\u7597\u6f5c\u529b\u3002\u8fc4\u4eca\u4e3a\u6b62\uff0c\u6211\u4eec\u4f7f\u7528\u8be5\u5e73\u53f0\u83b7\u5f97\u4e86\u4e09\u79cd\u6cbb\u7597\u65b9\u5f0f\u7684\u4f53\u5916\u6982\u5ff5\u9a8c\u8bc1\uff0c\u5e76\u53d1\u73b0\u7c7b\u4f3c\u836f\u7269\u7684\u4f53\u5185\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u6027\u53ca\u80bf\u7624\u751f\u7269\u5206\u5e03\u3002<\/li>\n<\/ul>\n<p><b>IV.&nbsp;&nbsp; \u6218\u7565\u5173\u7cfb\u4fc3\u8fdb\u5546\u4e1a\u5316\u6d3b\u52a8\u53ca\u7ba1\u7ebf\u5f00\u53d1<\/b><\/p>\n<p>\u6211\u4eec\u4e0d\u65ad\u53d1\u5c55\u4e0e\u6df1\u5316\u548c\u5168\u7403\u4e3b\u8981\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u7684\u5173\u7cfb\uff0c\u6269\u5c55\u5df2\u4e0a\u5e02\u53ca\u665a\u671f\u836f\u7269\u7684\u5546\u4e1a\u5316\uff0c\u5de9\u56fa\u6211\u4eec\u6f5c\u5728\u540c\u7c7b\u9996\u521b\/\u540c\u7c7b\u6700\u4f18\u7684\u65e9\u671f\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u83b7\u53d6\u66f4\u591a\u80fd\u591f\u52a0\u5f3a\u6211\u4eec\u7814\u53d1\u5b9e\u529b\u7684\u6280\u672f\u3002<\/p>\n<p>Blueprint Medicines\u4e8e2023\u5e742\u670822\u65e5\u5ba3\u5e03\uff0c\u5176\u5c06\u81ea\u7f57\u6c0f\u91cd\u65b0\u83b7\u5f97\u666e\u62c9\u66ff\u5c3c\u7684\u5168\u7403\u5546\u4e1a\u5316\u53ca\u5f00\u53d1\u6743\uff08\u4e0d\u5305\u62ec\u5927\u4e2d\u534e\u533a\uff09\u3002\u6709\u5173\u6743\u5229\u8fc7\u6e21\u5c06\u9884\u8ba1\u4e8e2024\u5e742\u6708\u751f\u6548\uff0c\u4e14Blueprint Medicines\u5df2\u542f\u52a8\u666e\u62c9\u66ff\u5c3c\u5728\u5927\u4e2d\u534e\u533a\u4ee5\u5916\u5730\u533a\u7684\u91cd\u65b0\u5408\u4f5c\u8fdb\u7a0b\u3002\u6211\u4eec\u73b0\u6b63\u4e0e\u7f57\u6c0f\u53caBlueprint Medicines\u5408\u4f5c\u91c7\u53d6\u5fc5\u8981\u63aa\u65bd\uff0c\u4ee5\u786e\u4fdd\u53ef\u4e3a\u5927\u4e2d\u534e\u533a\u60a3\u8005\u6301\u7eed\u4f9b\u5e94\u666e\u62c9\u66ff\u5c3c\u3002<\/p>\n<p>\u6839\u636e\u6211\u4eec\u4e0e\u6c5f\u82cf\u6052\u745e\u533b\u836f\u80a1\u4efd\u6709\u9650\u516c\u53f8\u5c31\u6297CTLA-4 \u5355\u514b\u9686\u6297\u4f53(CS1002)\u5efa\u7acb\u7684\u5408\u4f5c\u5173\u7cfb\uff0c\u6052\u745e\u6b63\u5728\u8fdb\u884c\u5173\u4e8eCS1002\u8054\u5408\u7597\u6cd5\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u5b9e\u4f53\u7624\uff08\u5305\u62ecHCC\u53caNSCLC\uff09\u7684Ib\/II\u671f\u8bd5\u9a8c\u3002<\/p>\n<p>\u968f\u7740\u57fa\u77f3\u836f\u4e1a\u4e0eEQRx\u5c31\u8212\u683c\u5229\u5355\u6297\u53canofazinlimab\u8ba2\u7acb\u7684\u6388\u6743\u534f\u8bae\u4e8e2023\u5e745\u67089\u65e5\u7ec8\u6b62\uff0c\u6211\u4eec\u91cd\u65b0\u83b7\u5f97\u8212\u683c\u5229\u5355\u6297\u53canofazinlimab\u4e8e\u5927\u4e2d\u534e\u533a\u4ee5\u5916\u5730\u533a\u7684\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u6743\u5229\u3002\u6709\u5173\u6743\u5229\u8fc7\u6e21\u5df2\u4e8e2023\u5e748\u6708\u5b8c\u6210\u3002\u6211\u4eec\u76ee\u524d\u6b63\u4e3b\u5bfc\u914d\u5408EMA\u53ca\u82f1\u56fdMHRA\u5bf9\u8212\u683c\u5229\u5355\u6297\u8fdb\u884cMAA\u5ba1\u67e5\u7684\u76d1\u7ba1\u6d41\u7a0b\u3002\u7ec8\u6b62\u8be5\u6388\u6743\u534f\u8bae\u5c06\u4e0d\u4f1a\u5f71\u54cd\u5148\u524d\u81eaEQRx\u6536\u53d6\u7684\u9884\u4ed8\u6b3e\u53ca\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u6211\u4eec\u76ee\u524d\u6b63\u5728\u5bfb\u6c42\u8212\u683c\u5229\u5355\u6297\u53canofazinlimab\u4e8e\u5927\u4e2d\u534e\u533a\u4ee5\u5916\u5730\u533a\u7684\u6f5c\u5728\u5408\u4f5c\u3002<\/p>\n<p><b>V.&nbsp;&nbsp;&nbsp; \u5176\u4ed6\u4e1a\u52a1\u8fdb\u5c55<\/b><\/p>\n<p><b>\u751f\u4ea7\u3002<\/b>\u6211\u4eec\u4ea6\u6b63\u5728\u8fdb\u884c\u591a\u6b3e\u8fdb\u53e3\u4ea7\u54c1\u7684\u6280\u672f\u8f6c\u79fb\uff0c\u9884\u8ba1\u5c06\u964d\u4f4e\u6210\u672c\uff0c\u63d0\u9ad8\u6211\u4eec\u4ea7\u54c1\u7684\u957f\u671f\u76c8\u5229\u80fd\u529b\u3002\u5177\u4f53\u800c\u8a00\uff0c\u6709\u5173\u963f\u4f10\u66ff\u5c3c\u7684\u6280\u672f\u8f6c\u79fb\u7533\u8bf7\u6b63\u5728CDE\u5ba1\u6838\u4e2d\u3002\u540c\u65f6\uff0c\u666e\u62c9\u66ff\u5c3c\u7684\u6280\u672f\u8f6c\u79fb\u6b63\u5728\u987a\u5229\u8fdb\u884c\u4e14\u5df2\u542f\u52a8\u751f\u7269\u7b49\u6548\u6027\u7814\u7a76\u3002<\/p>\n<p><b>\u672a\u6765\u53ca\u613f\u666f<\/b><\/p>\n<p>\u6211\u4eec\u6b63\u81f4\u529b\u4e8e\u5e26\u6765\u591a\u4e2a\u91cd\u5927\u4e34\u5e8a\u53ca\u5546\u4e1a\u8fdb\u5c55\uff0c\u4ee5\u4fc3\u8fdb\u6211\u4eec\u5728\u672a\u6765\u5341\u4e8c\u4e2a\u6708\u7684\u589e\u957f\u3002<\/p>\n<p>\u672a\u6765\u5341\u4e8c\u4e2a\u6708\u7684\u9884\u671f\u8fdb\u5c55\u660e\u7ec6\u5982\u4e0b\uff1a<\/p>\n<p><b>\u5546\u4e1a\u8fdb\u5c55<\/b><\/p>\n<p>\u6211\u4eec\u7684\u5546\u4e1a\u56e2\u961f\u6b63\u5728\u52aa\u529b\u52a0\u5feb\u6269\u5927\u4ea7\u54c1\u7684\u6f5c\u5728\u5e02\u573a\u5e76\u6700\u5927\u9650\u5ea6\u5730\u53d1\u6325\u5176\u5546\u4e1a\u6f5c\u529b\uff0c\u4e3b\u8981\u7740\u91cd\u4ee5\u4e0b\u65b9\u9762\uff1a<\/p>\n<ul type=\"disc\">\n<li>\u901a\u8fc7\u6700\u5927\u5316\u90e8\u7f72\u6548\u7387\u53ca\u5229\u7528\u6570\u5b57\u5e73\u53f0\u63d0\u9ad8\u5e02\u573a\u8986\u76d6\u7387<\/li>\n<li>\u901a\u8fc7\u4e0e\u8bca\u65ad\u516c\u53f8\u3001\u884c\u4e1a\u534f\u4f1a\uff08\u5982\u56fd\u5bb6\u75c5\u7406\u8d28\u63a7\u4e2d\u5fc3\uff09\u3001\u60a3\u8005\u5e73\u53f0\u53ca\u5927\u6570\u636e\u516c\u53f8\u7684\u6df1\u5ea6\u5408\u4f5c\uff0c\u63d0\u9ad8\u8bca\u65ad\u7387\u548c\u7cbe\u51c6\u7387<\/li>\n<li>\u901a\u8fc7\u7eb3\u5165\u6307\u5357\u3001\u4e3e\u529e\u5b66\u672f\u6d3b\u52a8\u53ca\u5f00\u5c55\u83b7\u6279\u540e\u7684\u4e34\u5e8a\u9879\u76ee\uff0c\u805a\u7126\u4e34\u5e8a\u5dee\u5f02\u5316\u548c\u5b89\u5168\u6027\uff0c\u63d0\u9ad8\u54c1\u724c\u5f71\u54cd\u529b\u53ca\u79d1\u5b66\u9886\u5bfc\u529b<\/li>\n<li>\u6301\u7eed\u63a8\u8fdb\u533b\u9662\u53caDTP\u5217\u540d\u6765\u52a0\u5f3a\u53ef\u53ca\u6027<\/li>\n<li>\u901a\u8fc7\u4f18\u5316\u5b9a\u4ef7\u7b56\u7565\u53ca\u5546\u4e1a\u4fdd\u9669\/\u521b\u65b0\u652f\u4ed8\u8ba1\u5212\uff0c\u63d0\u9ad8\u53ef\u8d1f\u62c5\u6027<\/li>\n<li>\u901a\u8fc7\u60a3\u8005\u96c6\u4f53\u53c2\u4e0e\u3001\u6559\u80b2\u4f1a\u8bae\u53ca\u540e\u7eed\u5229\u7528\u6570\u5b57\u5e73\u53f0\uff0c\u52a0\u5f3a\u60a3\u8005\u6559\u80b2\u53ca\u652f\u6301<\/li>\n<\/ul>\n<p><b>\u7814\u53d1<\/b><\/p>\n<p><b>\u9884\u671f<\/b><b>NDA\u6279\u51c6\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li>\u8212\u683c\u5229\u5355\u6297\uff1a2023\u5e74\u5e95\u524d\u5728\u4e2d\u56fd\u5927\u9646\u83b7\u5f97R\/R ENKTL\u7684NDA\u6279\u51c6<\/li>\n<li>\u8212\u683c\u5229\u5355\u6297\uff1a2024\u5e74\u4e0a\u534a\u5e74\u5728\u6b27\u76df\u83b7\u5f97\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597IV\u671fNSCLC\u7684MAA\u6279\u51c6<\/li>\n<li>\u8212\u683c\u5229\u5355\u6297\uff1a2024\u5e74\u4e0a\u534a\u5e74\u5728\u82f1\u56fd\u83b7\u5f97\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597IV\u671fNSCLC\u7684MAA\u6279\u51c6<\/li>\n<li>\u8212\u683c\u5229\u5355\u6297\uff1a2023\u5e74\u5e95\u62162024\u5e74\u4e0a\u534a\u5e74\u5728\u4e2d\u56fd\u5927\u9646\u83b7\u5f97\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u665a\u671fGC\/GEJ\u7684NDA\u6279\u51c6<\/li>\n<li>\u8212\u683c\u5229\u5355\u6297\uff1a2023\u5e74\u5e95\u62162024\u5e74\u4e0a\u534a\u5e74\u5728\u4e2d\u56fd\u5927\u9646\u83b7\u5f97\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u665a\u671fESCC\u7684NDA\u6279\u51c6<\/li>\n<\/ul>\n<p><b>\u9884\u671f<\/b><b>NDA\u7533\u8bf7\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li>\u6d1b\u62c9\u66ff\u5c3c\uff1a2024\u5e74\u5728\u4e2d\u56fd\u5927\u9646\u5c31ROS1\u9633\u6027\u665a\u671fNSCLC\u63d0\u4ea4\u8865\u5145NDA\u7533\u8bf7<\/li>\n<\/ul>\n<p><b>\u9884\u671f\u4e3b\u8981\u7814\u7a76\u7ed3\u679c\u53d1\u5e03\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li>\u8212\u683c\u5229\u5355\u6297\uff1a2023\u5e74\u7b2c\u4e09\u5b63\u5ea6\u53d1\u5e03\u8212\u683c\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u665a\u671fGC\/GEJ\u60a3\u8005\u7684GEMSTONE-303\u7814\u7a76\u9884\u8bbe\u7684\u603b\u751f\u5b58\u671f\u6700\u7ec8\u5206\u6790\u4e3b\u8981\u7814\u7a76\u7ed3\u679c<\/li>\n<li>Nofazinlimab\uff1a2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u53d1\u5e03nofazinlimab\u8054\u5408LENVIMA<sup>&reg;<\/sup>(lenvatinib)\u4e00\u7ebf\u6cbb\u7597\u665a\u671fHCC\u60a3\u8005III\u671f\u5168\u7403\u8bd5\u9a8c\u4e3b\u8981\u7814\u7a76\u7ed3\u679c<\/li>\n<\/ul>\n<p><b>\u65e9\u671f\u4e34\u5e8a\u9879\u76ee\uff1a<\/b><\/p>\n<p>\u2022&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; CS5001\uff1a<span id=\"spanHghltddf3\">2023\u5e74\u5e95\u66f4\u65b0\u4e34\u5e8a\u5b89\u5168\u6027\u53ca\u6709\u6548\u6027\u7684\u6570\u636e\u53ca\u4e8e2024\u5e74\u4e0a\u534a\u5e74\u5728\u5927\u4f1a\u5c55\u793a\u6570\u636e<\/span><\/p>\n<p><b>\u8d22\u52a1\u6458\u8981<\/b><\/p>\n<p><b>\u56fd\u9645\u8d22\u52a1\u62a5\u544a\u51c6\u5219\u8ba1\u91cf\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u6536\u5165<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u4e3a\u4eba\u6c11\u5e012.615\u4ebf\u5143\uff0c\u5305\u62ec\u836f\u54c1\u9500\u552e\u6536\u5165\u4eba\u6c11\u5e012.469\u4ebf\u5143\uff08\u5305\u62ec\u963f\u4f10\u66ff\u5c3c\u3001\u666e\u62c9\u66ff\u5c3c\u53ca\u827e\u4f0f\u5c3c\u5e03\uff09\u53ca\u8212\u683c\u5229\u5355\u6297\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u6536\u5165\u4eba\u6c11\u5e011,462\u4e07\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u836f\u54c1\u9500\u552e\u6536\u5165\u4eba\u6c11\u5e011.614\u4ebf\u5143\uff0c\u589e\u52a0\u4e86\u4eba\u6c11\u5e018,550\u4e07\u5143\u621653%\u53ca\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u6536\u5165\u4eba\u6c11\u5e011,310\u4e07\u5143\uff0c\u589e\u52a0\u4eba\u6c11\u5e01152\u4e07\u5143\u621611%\u3002<\/li>\n<li><b>\u7814\u53d1\u5f00\u652f<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u4e3a\u4eba\u6c11\u5e011.868\u4ebf\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u7814\u53d1\u5f00\u652f\u51cf\u5c11\u4eba\u6c11\u5e017,980\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e\u91cc\u7a0b\u7891\u8d39\u7528\u53ca\u7b2c\u4e09\u65b9\u5408\u7ea6\u6210\u672c\u4ee5\u53ca\u96c7\u5458\u6210\u672c\u51cf\u5c11\u6240\u81f4\u3002<\/li>\n<li><b>\u884c\u653f\u5f00\u652f<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u4e3a\u4eba\u6c11\u5e018,920\u4e07\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u884c\u653f\u5f00\u652f1.348\u4ebf\u5143\u51cf\u5c11\u4e86\u4eba\u6c11\u5e014,560\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e\u96c7\u5458\u6210\u672c\u51cf\u5c11\u6240\u81f4\u3002<\/li>\n<li><b>\u9500\u552e\u53ca\u5e02\u573a\u63a8\u5e7f\u5f00\u652f<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u4e3a\u4eba\u6c11\u5e011.314\u4ebf\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u9500\u552e\u53ca\u5e02\u573a\u63a8\u5e7f\u5f00\u652f\u4eba\u6c11\u5e011.464\u4ebf\u5143\u51cf\u5c11\u4e861,500\u4e07\u5143\uff0c\u4e3b\u8981\u5f52\u56e0\u4e8e\u96c7\u5458\u6210\u672c\u53ca\u4e13\u4e1a\u8d39\u7528\u51cf\u5c11\u6240\u81f4\u3002<\/li>\n<li><b>\u671f\u5185\u4e8f\u635f<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u4e3a\u4eba\u6c11\u5e012.092\u4ebf\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u671f\u5185\u4e8f\u635f\u4eba\u6c11\u5e013.616\u4ebf\u5143\u51cf\u5c11\u4e86\u4eba\u6c11\u5e011.524\u4ebf\u5143\u621642%\uff0c\u4e3b\u8981\u5f52\u56e0\u4e8e\u7814\u53d1\u5f00\u652f\u51cf\u5c11\u53ca\u96c7\u5458\u6210\u672c\u51cf\u5c11\u6240\u81f4\u3002<\/li>\n<\/ul>\n<p><b>\u975e\u56fd\u9645\u8d22\u52a1\u62a5\u544a\u51c6\u5219\u8ba1\u91cf\uff1a<\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u7814\u53d1\u5f00\u652f<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\uff0c\u6263\u9664\u4ee5\u80a1\u4efd\u4e3a\u57fa\u7840\u7684\u4ed8\u6b3e\u5f00\u652f\u540e\u4e3a\u4eba\u6c11\u5e011.981\u4ebf\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u4eba\u6c11\u5e012.189\u4ebf\u5143\u51cf\u5c11\u4eba\u6c11\u5e012,080\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e\u91cc\u7a0b\u7891\u8d39\u7528\u53ca\u7b2c\u4e09\u65b9\u5408\u7ea6\u6210\u672c\u4ee5\u53ca\u96c7\u5458\u6210\u672c\u964d\u4f4e\u3002<\/li>\n<li><b>\u884c\u653f\u4ee5\u53ca\u9500\u552e\u53ca\u5e02\u573a\u63a8\u5e7f\u5f00\u652f<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\uff0c\u6263\u9664\u4ee5\u80a1\u4efd\u4e3a\u57fa\u7840\u7684\u4ed8\u6b3e\u5f00\u652f\u540e\u4e3a\u4eba\u6c11\u5e011.831\u4ebf\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u4eba\u6c11\u5e012.244\u4ebf\u5143\u51cf\u5c11\u4eba\u6c11\u5e014,130\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e\u96c7\u5458\u6210\u672c\u53ca\u4e13\u4e1a\u8d39\u7528\u51cf\u5c11\u6240\u81f4\u3002<\/li>\n<li><b>\u671f\u5185\u4e8f\u635f<\/b>\u622a\u81f32023\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\uff0c\u6263\u9664\u4ee5\u80a1\u4efd\u4e3a\u57fa\u7840\u7684\u4ed8\u6b3e\u5f00\u652f\u540e\u4e3a\u4eba\u6c11\u5e011.83\u4ebf\u5143\uff0c\u8f83\u622a\u81f32022\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u4eba\u6c11\u5e012.571\u4ebf\u5143\u51cf\u5c11\u4eba\u6c11\u5e017,410\u4e07\u5143\u621629%\uff0c\u4e3b\u8981\u7531\u4e8e\u7814\u53d1\u5f00\u652f\u51cf\u5c11\u53ca\u96c7\u5458\u6210\u672c\u964d\u4f4e\u3002<\/li>\n<\/ul>\n<p><b>\u5173\u4e8e\u57fa\u77f3\u836f\u4e1a<\/b><\/p>\n<p>\u57fa\u77f3\u836f\u4e1a\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801: 2616\uff09\u662f\u4e00\u5bb6\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u7814\u7a76\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u521b\u65b0\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u53ca\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\uff0c\u4ee5\u6ee1\u8db3\u4e2d\u56fd\u548c\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u6bb7\u5207\u533b\u7597\u9700\u6c42\u3002\u6210\u7acb\u4e8e2015\u5e74\u5e95\uff0c\u57fa\u77f3\u836f\u4e1a\u5df2\u96c6\u7ed3\u4e86\u4e00\u652f\u5728\u65b0\u836f\u7814\u53d1\u3001\u4e34\u5e8a\u7814\u7a76\u4ee5\u53ca\u5546\u4e1a\u8fd0\u8425\u65b9\u9762\u62e5\u6709\u4e30\u5bcc\u7ecf\u9a8c\u7684\u7ba1\u7406\u56e2\u961f\u3002\u516c\u53f8\u4ee5\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u8054\u5408\u7597\u6cd5\u4e3a\u6838\u5fc3\uff0c\u5efa\u7acb\u4e86\u4e00\u676114\u79cd\u80bf\u7624\u5019\u9009\u836f\u7269\u7ec4\u6210\u7684\u4e30\u5bcc\u4ea7\u54c1\u7ba1\u7ebf\u3002\u76ee\u524d\uff0c\u57fa\u77f3\u836f\u4e1a\u5df2\u7ecf\u83b7\u5f97\u4e86\u56db\u6b3e\u521b\u65b0\u836f\u7684\u5341\u4e00\u9879\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u7684\u6279\u51c6\u3002\u591a\u6b3e\u540e\u671f\u5019\u9009\u836f\u7269\u6b63\u5904\u4e8e\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u6216\u6ce8\u518c\u9636\u6bb5\u3002\u57fa\u77f3\u836f\u4e1a\u7684\u613f\u666f\u662f\u6210\u4e3a\u4eab\u8a89\u5168\u7403\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u5f15\u9886\u653b\u514b\u764c\u75c7\u4e4b\u8def\u3002<\/p>\n<p>\u5982\u9700\u4e86\u89e3\u6709\u5173\u57fa\u77f3\u836f\u4e1a\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u6d4f\u89c8\uff1a<a href=\"https:\/\/www.cstonepharma.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.cstonepharma.com<\/a>\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u6587\u6240\u4f5c\u51fa\u7684\u524d\u77bb\u6027\u9648\u8ff0\u4ec5\u4e0e\u672c\u6587\u4f5c\u51fa\u8be5\u9648\u8ff0\u5f53\u65e5\u7684\u4e8b\u4ef6\u6216\u8d44\u6599\u6709\u5173\u3002\u9664\u6cd5\u5f8b\u89c4\u5b9a\u5916\uff0c\u4e8e\u4f5c\u51fa\u524d\u77bb\u6027\u9648\u8ff0\u5f53\u65e5\u4e4b\u540e\uff0c\u65e0\u8bba\u662f\u5426\u51fa\u73b0\u65b0\u8d44\u6599\u3001\u672a\u6765\u4e8b\u4ef6\u6216\u5176\u4ed6\u60c5\u51b5\uff0c\u6211\u4eec\u5e76\u65e0\u8d23\u4efb\u66f4\u65b0\u6216\u516c\u5f00\u4fee\u6539\u4efb\u4f55\u524d\u77bb\u6027\u9648\u8ff0\u53ca\u9884\u6599\u4e4b\u5916\u7684\u4e8b\u4ef6\u3002\u8bf7\u7ec6\u9605\u672c\u6587\uff0c\u5e76\u7406\u89e3\u6211\u4eec\u7684\u5b9e\u9645\u672a\u6765\u4e1a\u7ee9\u6216\u8868\u73b0\u53ef\u80fd\u4e0e\u9884\u671f\u6709\u91cd\u5927\u5dee\u5f02\u3002\u672c\u6587\u5185\u6240\u6709\u9648\u8ff0\u4e43\u672c\u6587\u7ae0\u520a\u53d1\u65e5\u671f\u4f5c\u51fa\uff0c\u53ef\u80fd\u56e0\u672a\u6765\u53d1\u5c55\u800c\u51fa\u73b0\u53d8\u52a8\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2023\u5e74\u4e0a\u534a\u5e74\u603b\u6536\u5165\u4e3a\u4eba\u6c11\u5e012.615\u4ebf\u5143\uff0c\u5176\u4e2d\u5546\u4e1a\u5316\u4ea7\u54c1\u9500\u552e\u6536\u5165\u4e3a\u4eba\u6c11\u5e012.469\u4ebf\u5143\uff0c\u8f83\u53bb\u5e74\u540c\u671f\u589e\u957f53%\u3002\u5546\u4e1a\u5316\u6bdb\u5229\u7387\u7531\u53bb\u5e74\u540c\u671f\u768447%\u63d0\u5347\u523059%\u3002 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\u5bb6\u533b\u9662\u6210\u529f\u6269\u5f20\u81f3\u903e180\u4e2a\u57ce\u5e02\u7684\u7ea6850\u5bb6\uff0c\u5360\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u76f8\u5173\u5e02\u573a\u7684\u7ea675%\u81f380%\uff0c\u6211\u4eec\u76f8\u4fe1\u6211\u4eec\u80fd\u591f\u6700\u5927\u7a0b\u5ea6\u5730\u63d0\u9ad8\u6211\u4eec\u7684\u9500\u552e\u56de\u62a5\u7387\u3002 \u2022&nbsp; \u4e0e\u5173\u952e\u5229\u76ca\u76f8\u5173\u8005\u5f62\u6210\u7cbe\u51c6\u8bca\u65ad\u751f\u6001\u7cfb\u7edf\uff0c\u4fc3\u8fdb\u60a3\u8005\u8bc6\u522b &#8211;&nbsp;&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2023081523100091823\">Read 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