{"id":9133,"date":"2020-11-09T20:12:00","date_gmt":"2020-11-09T13:12:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/202011092012009133"},"modified":"2020-11-09T21:44:21","modified_gmt":"2020-11-09T13:44:21","slug":"%e5%a4%a9%e5%a2%83%e7%94%9f%e7%89%a9%e5%9c%a82020%e5%b9%b4sitc%e5%b9%b4%e4%bc%9a%e5%85%ac%e5%b8%83lemzoparlimab%e7%9a%841%e6%9c%9f%e4%b8%b4%e5%ba%8a%e7%a0%94%e7%a9%b6%e7%bb%93%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/202011092012009133","title":{"rendered":"\u5929\u5883\u751f\u7269\u57282020\u5e74SITC\u5e74\u4f1a\u516c\u5e03Lemzoparlimab\u76841\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/APAC_Logo-6.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul type=\"disc\">\n<li><span><\/span><b><i><span>\u5355\u836f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u8bc1\u5b9e<\/span><\/i><\/b><b><i><span> lemzoparlimab<\/span><\/i><\/b><b><i><span>\u5177\u6709\u5dee\u5f02\u5316\u7684\u5b89\u5168\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66\u4f18\u52bf<\/span><\/i><\/b> <\/li>\n<li><span><\/span><b><i><span>\u5176\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6076\u6027\u80bf\u7624\u521d\u6b65\u663e\u793a\u7597\u6548\u4fe1\u53f7<\/span><\/i><\/b> <\/li>\n<li><span><\/span><b><i><span>\u5929\u5883\u751f\u7269\u5c06\u4e8e\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f4<\/span><\/i><\/b><b><i><span>11<\/span><\/i><\/b><b><i><span>\u6708<\/span><\/i><\/b><b><i><span>9<\/span><\/i><\/b><b><i><span>\u65e5\u65e9\u4e0a<\/span><\/i><\/b><b><i><span>8:30<\/span><\/i><\/b><b><i><span>\u53ec\u5f00\u6295\u8d44\u8005\u7535\u8bdd\u4f1a\u8bae<\/span><\/i><\/b><\/li>\n<\/ul>\n<p><p><span>\u4e2d\u56fd\u4e0a\u6d77\u548c\u7f8e\u56fd\u76d6\u745f\u65af\u5821<\/span>2020<span>\u5e74<\/span><span>11<\/span><span>\u6708<\/span><span>9<\/span><span>\u65e5<\/span> <span>\/\u7f8e\u901a\u793e\/ &#8212; \u5929\u5883\u751f\u7269\uff08\u201c\u516c\u53f8\u201d\uff09\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1a<\/span><span>IMAB<\/span><span>\uff09\u662f\u4e00\u5bb6\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u521b\u65b0\u751f\u7269\u836f\u7684\u9776\u70b9\u53d1\u73b0\u3001\u4e34\u5e8a\u5f00\u53d1\u548c\u4ea7\u54c1\u5546\u4e1a\u5316\uff0c\u4e3a\u5168\u7403\u8303\u56f4\u5185\u6cbb\u7597\u9700\u6c42\u8feb\u5207\u7684\u764c\u75c7\u6cbb\u7597\u9886\u57df\uff0c\u63d0\u4f9b\u65b0\u578b\u6709\u6548\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u516c\u53f8\u4eca\u5929\u5728\u7b2c<\/span><span>35<\/span><span>\u5c4a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u5b66\u4f1a\u5e74\u4f1a\uff08<\/span><span>SITC 2020<\/span><span>\uff09\u7ebf\u4e0a\u5927\u4f1a\u4ee5\u5b66\u672f\u6d77\u62a5\u7684\u5f62\u5f0f\uff08\u6d77\u62a5\u7f16\u53f7<\/span><span>385<\/span><span>\uff09\u516c\u5e03\u4e86\u5176\u81ea\u4e3b\u7814\u53d1\u7684<\/span><span>CD47<\/span><span>\u5355\u514b\u9686\u6297\u4f53<\/span><span>lemzoparlimab<\/span><span>\uff08\u4e5f\u79f0\u4e3a<\/span><span>TJC4<\/span><span>\uff09\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u5b9e\u4f53\u7624\u548c\u6dcb\u5df4\u7624\u7684\u7f8e\u56fd<\/span><span>1<\/span><span>\u671f\u4e34\u5e8a\u7814\u7a76\uff08<\/span><span>NCT03934814<\/span><span>\uff09\u7684\u521d\u6b65\u7ed3\u679c\u3002<\/span> <\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p><span>Lemzoparlimab\u662f\u7531\u5929\u5883\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u4e00\u6b3e\u9ad8\u5ea6\u5dee\u5f02\u5316\u7684<\/span><span>CD47<\/span><span>\u5355\u514b\u9686\u6297\u4f53\u3002\u5176\u5728\u4fdd\u7559\u5f3a\u5927\u7684\u6297\u80bf\u7624\u6d3b\u6027\u7684\u540c\u65f6\uff0c\u80fd\u591f\u6700\u5927\u7a0b\u5ea6\u5730\u51cf\u5c11\u4e0e\u6b63\u5e38\u7ea2\u7ec6\u80de\u7ed3\u5408\uff0c\u4ece\u800c\u907f\u514d\u540c\u7c7b<\/span><span>CD47<\/span><span>\u6297\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5e38\u89c1\u7684\u4e25\u91cd\u8d2b\u8840\u7b49\u6bd2\u526f\u4f5c\u7528\u3002<\/span><\/p>\n<p><span><\/span><\/p>\n<p>\u5929\u5883\u751f\u7269\u521b\u59cb\u4eba\u3001\u8363\u8a89\u8463\u4e8b\u957f\u517c\u8463\u4e8b\u81e7\u656c\u4e94\u535a\u58eb\u8868\u793a\uff1a\u201cLemzoparlimab\u662f\u7531\u5929\u5883\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u5177\u6709\u5168\u7403\u7ade\u4e89\u529b\u7684CD47\u6297\u4f53\uff0c\u5176\u521b\u65b0\u4e4b\u5904\u5728\u4e8e\u6211\u4eec\u7684\u7814\u53d1\u56e2\u961f\u901a\u8fc7\u5dee\u5f02\u5316\u8bbe\u8ba1\u548c\u9488\u5bf9\u6027\u7684\u7b5b\u9009\u53d1\u73b0\u4e86\u8bc6\u522bCD47\u6297\u539f\u72ec\u7279\u8868\u4f4d\u7684\u5355\u514b\u9686\u6297\u4f53\u3002\u7ecf\u6df1\u5165\u7814\u7a76\uff0c\u8be5\u8868\u4f4d\u4e0e\u7ea2\u7ec6\u80de\u819c\u8868\u9762\u7279\u6b8a\u7684\u7cd6\u57fa\u5316\u4fee\u9970\u76f8\u5173\uff0c\u5927\u5927\u964d\u4f4e\u4e86\u4e0e\u6b63\u5e38\u7ea2\u7ec6\u80de\u7ed3\u5408\uff0c\u4ece\u800c\u907f\u514d\u4e86\u8fd9\u7c7b\u6297\u4f53\u836f\u7269\u5e38\u89c1\u7684\u8840\u6db2\u7cfb\u7edf\u6bd2\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66\u4e0a\u7684\u2018\u6c89\u6ca1\u6548\u5e94\u2019\u3002\u6211\u4eec\u6b23\u559c\u5730\u770b\u5230lemzoparlimab\u5728\u5b89\u5168\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66\u65b9\u9762\u7684\u5dee\u5f02\u5316\u4f18\u52bf\u5f97\u5230\u8fdb\u4e00\u6b65\u9a8c\u8bc1\uff0c\u4f7f\u5176\u5728\u5168\u7403CD47\u6297\u4f53\u7684\u7814\u53d1\u961f\u5217\u4e2d\u8131\u9896\u800c\u51fa\u3002\u201d <\/p>\n<p>  <span><\/span>  <\/p>\n<p><span>Lemzoparlimab<\/span><span>\u7684<\/span><span>1<\/span><span>\u671f\u4e34\u5e8a\u8bd5\u9a8c\u662f\u4e00\u9879\u5f00\u653e\u6027\u3001\u591a\u4e2d\u5fc3\u3001\u591a\u5242\u91cf\u7684\u7814\u7a76\u3002\u5b83\u5206\u4e3a\u4e24\u4e2a\u90e8\u5206\uff0c\u7b2c\u4e00\u90e8\u5206\u5305\u62ec\u5355\u836f\u5242\u91cf\u9012\u589e\u4ee5\u53ca\u540e\u7eed\u4e24\u9879\u8054\u5408\u7528\u836f\u5242\u91cf\u9012\u589e\u7814\u7a76\uff08<\/span><span><span class=\"xn-money\">1b<\/span><\/span><span>\u90e8\u5206\u4e0e\u6d3e\u59c6\u5355\u6297\u8054\u7528\uff0c<\/span><span>1c<\/span><span>\u90e8\u5206\u4e0e\u5229\u59a5\u6614\u5355\u6297\u8054\u7528\uff09\uff0c<\/span><span> <\/span><span>\u7b2c\u4e8c\u90e8\u5206\u5219\u662f\u4e24\u9879\u8054\u5408\u7528\u836f\u6cbb\u7597\u7684<\/span><span>\u961f\u5217\u6269\u5c55<\/span><span>\u7814\u7a76\u3002<\/span><\/p>\n<p><span>\u5929\u5883\u751f\u7269\u6b64\u6b21\u516c\u5e03\u7684\u662f<\/span><span>lemzoparlimab<\/span><span>\u5355\u836f\u6cbb\u7597\u7684\u521d\u6b65\u6570\u636e<\/span><span>\uff08<\/span><span>20<\/span><span>\u4f8b\u60a3\u8005\uff09\uff0c\u5305\u62ec\u8be5\u5355\u836f\u6cbb\u7597\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\uff08<\/span><span>PK<\/span><span>\uff09\u3001\u836f\u6548\u5b66\uff08<\/span><span>PD<\/span><span>\uff09\u548c\u6297\u80bf\u7624\u6d3b\u6027\u3002<\/span><span>\u7ed3\u679c\u663e\u793a\uff1a<\/span><\/p>\n<ul type=\"disc\">\n<li><span><\/span><span>\u5728\u6ca1\u6709\u4efb\u4f55\u9884\u6fc0\u7ed9\u836f\u7684\u60c5\u51b5\u4e0b\uff0c<\/span><span>lemzoparlimab<\/span><span>\u6bcf\u5468\u7ed9\u836f\uff0c\u4ece\u6700\u4f4e\u5242\u91cf\uff08<\/span><span>1 mg\/kg<\/span><span>\uff09\u81f3\u6700\u9ad8\u5242\u91cf\uff08<\/span><span>30 mg\/kg<\/span><span>\uff09\u8303\u56f4\u5185\u663e\u793a\u51fa\u826f\u597d\u7684\u8010\u53d7\u6027\uff0c<\/span><span>\u5728\u6240\u6709\u5242\u91cf\u7ec4\u4e2d\u5747\u672a\u89c2\u5bdf\u5230\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\u548c\u6eb6\u8840\u6027\u8d2b\u8840<\/span><span>\u3002<\/span> <\/li>\n<li><span><\/span><span>\u5728\u4e2d\u81f3\u9ad8\u5242\u91cf\uff0c<\/span><span>lemzoparlimab<\/span><span>\u5355\u5242\u6ce8\u5c04\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u5448\u7ebf\u6027\uff0c\u65e0\u660e\u663e\u6297\u539f\u201c\u6c89\u6ca1\u6548\u5e94\u201d\u3002<\/span> <\/li>\n<li><span><\/span><span>\u5728<\/span><span>30 mg\/kg<\/span><span>\u5242\u91cf\u7ec4\u7684\u4e09\u4f8b\u60a3\u8005\u4e2d\uff0c\u4e00\u4f8b\u7ecf\u8fc7\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u5931\u8d25\u7684\u60a3\u8005\u5728\u63a5\u53d7<\/span><span>lemzoparlimab<\/span><span>\u6cbb\u7597\u540e\u786e\u8ba4\u90e8\u5206\u7f13\u89e3\uff08<\/span><span>PR<\/span><span>\uff09\u3002<\/span><\/li>\n<\/ul>\n<p><span>\u8be5\u9879\u7814\u7a76\u7684\u4e3b\u8981\u7814\u7a76\u8005\u3001\u8303\u5fb7\u5821\u5927\u5b66<\/span><span><span class=\"xn-person\">Jordan Berlin<\/span><\/span><span>\u535a\u58eb\u8868\u793a\uff1a\u201c<\/span><span>Lemzoparlimab <\/span><span>\u7684<\/span><span>1<\/span><span>\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u7814\u7a76\u7ed3\u679c\u4ee4\u6211\u4eec\u611f\u5230\u975e\u5e38\u9f13\u821e\u3002\u8be5\u7814\u7a76\u7ed3\u679c\u663e\u793a\u4e86\u5176\u4f5c\u4e3a\u4e00\u79cd\u9ad8\u5ea6\u5dee\u5f02\u5316\u7684<\/span><span>CD47<\/span><span>\u6297\u4f53\u7528\u4e8e\u6cbb\u7597\u591a\u79cd\u764c\u75c7\u7684\u524d\u666f\uff0c\u6211\u4eec\u5341\u5206\u671f\u5f85\u63a8\u8fdb\u5176\u5728\u6cbb\u7597\u665a\u671f\u5b9e\u4f53\u7624\u548c\u6076\u6027\u8840\u6db2\u7cfb\u7edf\u80bf\u7624\u60a3\u8005\u7684\u7814\u7a76\u8fdb\u5c55\u3002\u201d<\/span><span><span class=\"xn-person\">Jordan Berlin<\/span><\/span><span>\u535a\u58eb\u5c06\u4e8e<\/span><span>2020<\/span><span>\u5e74<\/span><span>11<\/span><span>\u6708<\/span><span>11<\/span><span>\u65e5\u4e0b\u5348<\/span><span>5:15-5:45<\/span><span>\u53ca<\/span><span>11<\/span><span>\u6708<\/span><span>13<\/span><span>\u65e5\u4e0b\u5348<\/span><span>4:40-5:10<\/span><span>\uff08\u5747\u4e3a\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f4\uff09\u4e8e\u7ebf\u4e0a\u5c55\u793a\u76f8\u5173\u7814\u7a76\u6570\u636e\u3002<\/span><\/p>\n<p><span>\u76ee\u524d\uff0c<\/span><span>lemzoparlimab<\/span><span>\u8054\u5408\u6d3e\u59c6\u5355\u6297\u6216\u5229\u59a5\u6614\u5355\u6297\u7684\u5242\u91cf\u9012\u589e\u7814\u7a76\u6b63\u5904\u4e8e\u53d7\u8bd5\u8005\u62db\u52df\u9636\u6bb5\u3002\u6709\u5173\u8be5\u4e34\u5e8a\u8bd5\u9a8c\uff08<\/span><span>NCT03934814<\/span><span>\uff09\u7684\u66f4\u591a\u4fe1\u606f\u656c\u8bf7\u8bbf\u95ee\uff1a<\/span><span><a target=\"_blank\" href=\"http:\/\/www.clinicaltrials.gov\/\" rel=\"nofollow noopener noreferrer\">www.clinicaltrials.gov<\/a><\/span><span>\u3002<\/span><\/p>\n<p><span>2020<\/span><span>\u5e74<\/span><span>9<\/span><span>\u6708\uff0c\u5929\u5883\u751f\u7269\u4e0e\u827e\u4f2f\u7ef4\u5c31<\/span><span>lemzoparlimab<\/span><span>\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u5efa\u7acb\u5e7f\u6cdb\u7684\u5168\u7403\u6218\u7565\u5408\u4f5c\u5173\u7cfb\u3002\u6839\u636e\u5408\u4f5c\u534f\u8bae\uff0c\u53cc\u65b9\u5c06\u6309\u7167\u7ea6\u5b9a\u5171\u540c\u5728\u5168\u7403\u8303\u56f4\u5f00\u5c55\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u8fdb\u4e00\u6b65\u8bc4\u4f30<\/span><span>lemzoparlimab<\/span><span>\u6cbb\u7597\u591a\u79cd\u764c\u75c7\u7684\u6f5c\u529b\u3002<\/span><\/p>\n<p><b><span>\u5929\u5883\u751f\u7269\u7535\u8bdd\u4f1a\u8bae\u548c\u7f51\u7edc\u76f4\u64ad\u4fe1\u606f<\/span><\/b><\/p>\n<p><span>\u5929\u5883\u751f\u7269\u8bda\u9080\u6240\u6709\u6295\u8d44\u8005\u53ca\u5206\u6790\u5e08\u901a\u8fc7\u4ee5\u4e0b\u62e8\u5165\u53f7\u7801\u6536\u542c\u5c06\u4e8e\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f4\u4eca\u5929\u65e9\u4e0a<\/span><span>8<\/span><span>\u70b9\u534a\u53ec\u5f00\u7684\u7535\u8bdd\u4f1a\u8bae\u3002<\/span><\/p>\n<p><span><\/span><\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u7f8e\u56fd:<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">+1-888-346-8982<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u56fd\u9645:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">+1-412-902-4272<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u4e2d\u56fd\u5927\u9646\u7535\u8bdd:<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">400-120-1203<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u4e2d\u56fd\u9999\u6e2f\u7535\u8bdd:<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">800-905-945<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u4f1a\u8baeID:<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">10149942<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p><span>\u6295\u8d44\u8005\u53ca\u5206\u6790\u5e08\u8fd8\u53ef\u4ee5\u901a\u8fc7\u5929\u5883\u751f\u7269\u7684\u6295\u8d44\u8005\u5173\u7cfb\u7f51\u7ad9<\/span><span><a target=\"_blank\" href=\"http:\/\/ir.i-mabbiopharma.com\/\" rel=\"nofollow noopener noreferrer\">http:\/\/ir.i-mabbiopharma.com<\/a><\/span><span>\u6536\u542c\u7535\u8bdd\u4f1a\u8bae\u7684\u7f51\u7edc\u76f4\u64ad\u53ca\u91cd\u64ad\u3002<\/span><\/p>\n<p><span>\u7535\u8bdd\u4f1a\u8bae\u91cd\u64ad\u5c06\u5728\u901a\u8bdd\u7ed3\u675f\u540e\u7ea6\u4e24\u4e2a\u5c0f\u65f6\u63d0\u4f9b\u3002\u5982\u9700\u6536\u542c\u4f1a\u8bae\u91cd\u64ad\uff0c\u8bf7\u62e8\u6253<\/span><span> +1-877-344-7529 (<\/span><span>\u7f8e\u56fd<\/span><span>)<\/span><span>\uff0c\u6216<\/span><span>1-412-317-0088 (<\/span><span>\u56fd\u9645<\/span><span>)<\/span><span>\u3002\u91cd\u64ad\u7684\u4f1a\u8bae<\/span><span>ID<\/span><span>\u662f<\/span><span>10149942<\/span><span>\u3002\u7535\u8bdd\u91cd\u64ad\u5185\u5bb9\u4e8e<\/span><span>2020<\/span><span>\u5e74<\/span><span>11<\/span><span>\u6708<\/span><span>16<\/span><span>\u65e5\u524d\u6709\u6548\u3002<\/span><\/p>\n<p><b><span>\u5173\u4e8e<\/span><\/b><b><span>CD47<\/span><\/b><b><span>\u548c<\/span><\/b><b><span>Lemzoparlimab<\/span><\/b><\/p>\n<p><span>CD47<\/span><span>\u662f\u4e00\u79cd\u5e7f\u6cdb\u8868\u8fbe\u4e8e\u591a\u79cd\u764c\u7ec6\u80de\u8868\u9762\u7684\u7cd6\u86cb\u767d\uff0c\u901a\u8fc7\u4e0e\u80bf\u7624\u541e\u566c\u7ec6\u80de\u8868\u9762<\/span><span>SIRP\u03b1<\/span><span>\u8fde\u63a5\u91ca\u653e<\/span><span>\u201c<\/span><span>\u4e0d\u8981\u5403\u6211<\/span><span>\u201d<\/span><span>\u4fe1\u53f7\uff0c\u963b\u6b62\u5de8\u566c\u7ec6\u80de\u541e\u566c\u4f5c\u7528\u3002<\/span><span>CD47<\/span><span>\u6297\u4f53\u56e0\u53ef\u4ee5\u963b\u65ad\u6b64\u4fe1\u53f7\uff0c\u4f7f\u5de8\u566c\u7ec6\u80de\u653b\u51fb\u80bf\u7624\u7ec6\u80de\uff0c\u6545\u6210\u4e3a\u76ee\u524d\u6700\u6709\u5f00\u53d1\u524d\u666f\u7684\u80bf\u7624\u514d\u75ab\u9776\u70b9\u4e4b\u4e00\u3002\u4f46<\/span><span>CD47<\/span><span>\u6297\u4f53\u5728\u653b\u51fb\u80bf\u7624\u7ec6\u80de\u7684\u540c\u65f6\uff0c\u4f1a\u4e0e\u6b63\u5e38\u7ea2\u7ec6\u80de\u7684\u7ed3\u5408\u4ece\u800c\u5f15\u8d77\u8840\u6db2\u5b66\u526f\u4f5c\u7528\uff0c\u5982\u4e25\u91cd\u8d2b\u8840\uff0c\u8fd9\u4f7f\u5f97<\/span><span>CD47<\/span><span>\u6297\u4f53\u4f5c\u4e3a\u764c\u75c7\u6cbb\u7597\u624b\u6bb5\u7684\u7814\u53d1\u548c\u4e34\u5e8a\u5e94\u7528\u53d7\u5230\u963b\u788d\u3002\u5929\u5883\u751f\u7269\u7684\u79d1\u5b66\u5bb6\u7a81\u7834\u6027\u7684\u53d1\u73b0\u4e86\u4e00\u79cd\u72ec\u7279\u7684<\/span><span>CD47<\/span><span>\u6297\u4f53<\/span><span>lemzoparlimab<\/span><span>\uff0c\u5176\u80fd\u6709\u6548\u5730\u9776\u5411\u80bf\u7624\u7ec6\u80de\uff0c\u540c\u65f6\u5c06\u5bf9\u7ea2\u7ec6\u80de\u4ea7\u751f\u7684\u4e0d\u826f\u5f71\u54cd\u964d\u81f3\u6700\u4f4e\uff0c\u4ece\u800c\u53ef\u907f\u514d\u4e25\u91cd\u8d2b\u8840\u3002<\/span><\/p>\n<p><span>\u4e00\u7cfb\u5217\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u5df2\u5145\u5206\u8bc1\u5b9e<\/span><span>lemzoparlimab<\/span><span>\u7684\u8840\u6db2\u5b66\u5b89\u5168\u4f18\u52bf\u548c\u5353\u8d8a\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002\u5982\u4eca\uff0c\u5728\u764c\u75c7\u60a3\u8005\u4e2d\u8fdb\u884c\u7684<\/span><span>1<\/span><span>\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7ed3\u679c\u4e3a\u8fd9\u79cd\u5dee\u5f02\u5316\u63d0\u4f9b\u4e86\u8fdb\u4e00\u6b65\u7684\u4e34\u5e8a\u9a8c\u8bc1\u3002\u9664\u4e86\u76ee\u524d\u6b63\u5728\u4e2d\u56fd\u8fdb\u884c\u7684\u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5<\/span><span>\/<\/span><span>\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81\uff08<\/span><span>AML\/MDS<\/span><span>\uff09\u60a3\u8005\u4e34\u5e8a\u8bd5\u9a8c\u4ee5\u5916\uff0c\u5929\u5883\u751f\u7269\u8fd8\u5c06\u7ee7\u7eed\u5728\u7f8e\u56fd\u63a8\u8fdb<\/span><span>lemzoparlimab<\/span><span>\u4e0e<\/span><span>Keytruda&reg;<\/span><span>\uff08\u6d3e\u59c6\u5355\u6297\uff09\u8054\u5408\u6cbb\u7597\u5b9e\u4f53\u7624\uff0c\u4ee5\u53ca\u548c<\/span><span>Rituxan&reg;<\/span><span>\uff08\u5229\u59a5\u6614\u5355\u6297\uff09\u8054\u5408\u6cbb\u7597\u6dcb\u5df4\u7624\u7684\u7814\u7a76\u3002<\/span><\/p>\n<p><span>2020<\/span><span>\u5e74<\/span><span>9<\/span><span>\u6708\uff0c\u5929\u5883\u751f\u7269\u4e0e\u827e\u4f2f\u7ef4\u5c31<\/span><span>lemzoparlimab<\/span><span>\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u5efa\u7acb\u5e7f\u6cdb\u7684\u5168\u7403\u6218\u7565\u5408\u4f5c\u5173\u7cfb\u3002\u6839\u636e\u5408\u4f5c\u534f\u8bae\uff0c\u53cc\u65b9\u5c06\u5408\u4f5c\u8bbe\u8ba1\u5e76\u8fdb\u4e00\u6b65\u5728\u5168\u7403\u8303\u56f4\u5f00\u5c55\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u8bc4\u4f30<\/span><span>lemzoparlimab<\/span><span>\u5728\u591a\u79cd\u764c\u75c7\u4e2d\u7684\u6cbb\u7597\u6f5c\u529b\u3002\u53cc\u65b9\u5c06\u6309\u7167\u7ea6\u5b9a\u6761\u4ef6\u5171\u540c\u63a8\u8fdb\u76f8\u5173\u5408\u4f5c\u3002<\/span><\/p>\n<p><b><span>\u5173\u4e8e\u5929\u5883\u751f\u7269<\/span><\/b><\/p>\n<p><span>\u5929\u5883\u751f\u7269\u662f\u4e00\u5bb6\u5bcc\u6709\u6d3b\u529b\u7684\u56fd\u9645\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u805a\u7126\u80bf\u7624\u514d\u75ab\u548c\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u9886\u57df\u5dee\u5f02\u5316\u521b\u65b0\u751f\u7269\u836f\u7684\u7814\u53d1\uff0c\u4ee5<\/span><span>\u201c<\/span><span>\u6301\u7eed\u5f00\u53d1\u521b\u65b0\u751f\u7269\u836f\uff0c\u771f\u6b63\u6539\u53d8\u60a3\u8005\u751f\u6d3b<\/span><span>\u201d<\/span><span>\u4e3a\u4f7f\u547d\u3002\u5929\u5883\u751f\u7269\u5728<\/span><span>\u201c<\/span><span>\u5feb\u901f\u4ea7\u54c1\u4e0a\u5e02<\/span><span>\u201d<\/span><span>\u548c<\/span><span>\u201c<\/span><span>\u5feb\u901f\u6982\u5ff5\u9a8c\u8bc1<\/span><span>\u201d<\/span><span>\u7684\u53cc\u8f6e\u7b56\u7565\u9a71\u52a8\u4e0b\uff0c\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\u548c\u5168\u7403\u5408\u4f5c\u7b49\u591a\u5143\u5316\u6a21\u5f0f\uff0c\u8fc5\u901f\u5efa\u7acb\u8d77\u62e5\u6709\u5341\u591a\u4e2a\u5177\u6709\u5168\u7403\u7ade\u4e89\u529b\u7684\u521b\u65b0\u836f\u7814\u53d1\u7ba1\u7ebf\u3002\u5929\u5883\u751f\u7269\u51ed\u501f\u4f18\u79c0\u7684\u836f\u7269\u7814\u53d1\u56e2\u961f\u3001\u500d\u53d7\u8ba4\u53ef\u7684\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u5f00\u53d1\u5b9e\u529b\uff0c\u4ee5\u53ca\u4e16\u754c\u4e00\u6d41\u7684<\/span><span>GMP<\/span><span>\u751f\u4ea7\u80fd\u529b\uff0c\u6b63\u5feb\u901f\u6210\u957f\u4e3a\u8986\u76d6\u5168\u4ea7\u4e1a\u94fe\u7684\u7efc\u5408\u6027\u5168\u7403\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u5929\u5883\u751f\u7269\u5728\u5317\u4eac\u3001\u4e0a\u6d77\u3001\u676d\u5dde\u3001\u9999\u6e2f\u548c\u7f8e\u56fd\u9a6c\u91cc\u5170\u5dde\u5747\u8bbe\u6709\u529e\u516c\u5ba4\u3002\u66f4\u591a\u4fe1\u606f\u8bf7\u8bbf\u95ee<\/span><u><span><a target=\"_blank\" href=\"http:\/\/ir.i-mabbiopharma.com\/\" rel=\"nofollow noopener noreferrer\"><span>http:\/\/ir.i-mabbiopharma.com<\/span><\/a><\/span><\/u><span>\u5e76\u5173\u6ce8\u5929\u5883\u751f\u7269<\/span><u><span><a target=\"_blank\" href=\"https:\/\/www.linkedin.com\/company\/i-mab\/\" rel=\"nofollow noopener noreferrer\"><span>\u9886\u82f1<\/span><\/a><\/span><\/u><span>\u3001<\/span><span><a target=\"_blank\" href=\"https:\/\/twitter.com\/IMabBiopharma\" rel=\"nofollow noopener noreferrer\"><span>\u63a8\u7279<\/span><\/a><\/span><span>\u53ca<\/span><u><span><a target=\"_blank\" href=\"https:\/\/mp.weixin.qq.com\/s\/_s634aizyQPuq1Vgf-hLGA\" rel=\"nofollow noopener noreferrer\"><span>\u5fae\u4fe1<\/span><\/a><\/span><\/u><span>\u5b98\u65b9\u8d26\u53f7\u3002<\/span><\/p>\n<p><b><span>\u5929\u5883\u751f\u7269\u524d\u77bb\u6027\u58f0\u660e<\/span><\/b><\/p>\n<p><span>\u672c\u65b0\u95fb\u7a3f\u5305\u542b\u6839\u636e\u300a<\/span><span>1995 <\/span><span>\u5e74\u79c1\u4eba\u8bc1\u5238\u8bc9\u8bbc\u6539\u9769\u6cd5\u6848\u300b\u4ee5\u53ca\u5176\u4ed6\u8054\u90a6\u8bc1\u5238\u6cd5\u5f8b\u4e0b\u5b9a\u4e49\u7684\u524d\u77bb\u6027\u58f0\u660e\uff0c\u5305\u62ec\u6709\u5173<\/span><span>lemzo<\/span><span>parlimab<\/span><span>\uff08<\/span><span>TJC4<\/span><span>\uff09<\/span><span>\u7684<\/span><span>1<\/span><span>\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\uff0c\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u5bf9\u60a3\u8005\u4ea7\u751f\u7684\u6f5c\u5728\u5f71\u54cd\uff0c\u5929\u5883\u751f\u7269\u6709\u5173<\/span><span>lemzoparlimab<\/span><span>\uff08<\/span><span>TJC4<\/span><span>\uff09\u7684\u8fdb\u5c55\u53ca\u9884\u671f\u7684\u4e34\u5e8a\u5f00\u53d1\u8ba1\u5212\u3001\u836f\u653f\u91cc\u7a0b\u7891\u53ca\u5546\u4e1a\u5316\u3002\u7531\u4e8e\u5404\u79cd\u91cd\u8981\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4e0e\u524d\u77bb\u6027\u58f0\u660e\u6709\u91cd\u5927\u5dee\u5f02\u3002\u8fd9\u4e9b\u56e0\u7d20\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u4ee5\u4e0b\u4e8b\u9879\u7684\u98ce\u9669\uff1a\u5929\u5883\u751f\u7269\u8bc1\u660e\u5176\u5019\u9009\u836f\u7269\u5b89\u5168\u6027\u548c\u7597\u6548\u7684\u80fd\u529b\uff1b\u5019\u9009\u836f\u7269\u7684\u4e34\u5e8a\u7ed3\u679c\u53ef\u80fd\u4e0d\u652f\u6301\u8fdb\u4e00\u6b65\u5f00\u53d1\u6216\u65b0\u836f\u4e0a\u5e02\u5ba1\u6279\uff1b\u76f8\u5173\u76d1\u7ba1\u673a\u6784\u5c31\u5929\u5883\u751f\u7269\u5019\u9009\u836f\u7269\u7684\u76d1\u7ba1\u5ba1\u6279\u4f5c\u51fa\u51b3\u5b9a\u7684\u5185\u5bb9\u548c\u65f6\u95f4\uff1b\u5929\u5883\u751f\u7269\u7684\u5019\u9009\u836f\u7269\uff08\u5982\u80fd\u83b7\u6279\uff09\u83b7\u5f97\u5546\u4e1a\u6210\u529f\u7684\u80fd\u529b\uff1b\u5929\u5883\u751f\u7269\u5bf9\u5176\u6280\u672f\u548c\u836f\u7269\u77e5\u8bc6\u4ea7\u6743\u4fdd\u62a4\u83b7\u5f97\u548c\u7ef4\u62a4\u7684\u80fd\u529b\uff1b\u5929\u5883\u751f\u7269\u4f9d\u8d56\u7b2c\u4e09\u65b9\u8fdb\u884c\u836f\u7269\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u5176\u4ed6\u670d\u52a1\u7684\u60c5\u51b5\uff1b\u5929\u5883\u751f\u7269\u6709\u9650\u7684\u8fd0\u8425\u5386\u53f2\u548c\u83b7\u5f97\u8fdb\u4e00\u6b65\u7684\u8fd0\u8425\u8d44\u91d1\u4ee5\u5b8c\u6210\u5019\u9009\u836f\u7269\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7684\u80fd\u529b\uff1b\u65b0\u51a0\u75c5\u6bd2\u5bf9\u516c\u53f8\u4e34\u5e8a\u5f00\u53d1\u3001\u5546\u4e1a\u4ee5\u53ca\u5176\u4ed6\u4e1a\u52a1\u8fd0\u8425\u5e26\u6765\u7684\u5f71\u54cd\uff1b\u4ee5\u53ca\u5929\u5883\u751f\u7269\u5728\u6700\u8fd1\u5e74\u5ea6\u62a5\u544a<\/span><span>20-F<\/span><span>\u8868\u683c\u4e2d<\/span><span>\u201c<\/span><span>\u98ce\u9669\u56e0\u7d20<\/span><span>\u201d<\/span><span>\u7ae0\u8282\u91cc\u66f4\u5168\u9762\u8ba8\u8bba\u7684\u5404\u7c7b\u98ce\u9669\uff1b\u4ee5\u53ca\u5929\u5883\u751f\u7269\u5411\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\u671f\u540e\u5448\u62a5\u4e2d\u5173\u4e8e\u6f5c\u5728\u98ce\u9669\u3001\u4e0d\u786e\u5b9a\u6027\u4ee5\u53ca\u5176\u4ed6\u91cd\u8981\u56e0\u7d20\u7684\u8ba8\u8bba\u3002\u6240\u6709\u524d\u77bb\u6027\u58f0\u660e\u57fa\u4e8e\u5929\u5883\u751f\u7269\u76ee\u524d\u638c\u63e1\u7684\u4fe1\u606f\uff0c\u9664\u975e\u6cd5\u5f8b\u53e6\u6709\u8981\u6c42\uff0c\u5929\u5883\u751f\u7269\u6ca1\u6709\u4e49\u52a1\u56e0\u65b0\u4fe1\u606f\u3001\u65e5\u540e\u4e8b\u4ef6\u6216\u5176\u4ed6\u539f\u56e0\u800c\u516c\u5f00\u66f4\u65b0\u6216\u4fee\u8ba2\u4efb\u4f55\u524d\u77bb\u6027\u58f0\u660e\u7684\u4e49\u52a1\u3002<\/span><\/p>\n<p><b><span>\u5929\u5883\u751f\u7269<\/span><\/b><b><span>\u8054\u7cfb\u4eba<\/span><\/b><\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><\/span>&nbsp;<\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u6731\u6770\u4f26\uff0c\u9996\u5e2d\u8d22\u52a1\u5b98<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><u><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:jielun.zhu@i-mabbiopharma.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\"><span class=\"prnews_span\">jielun.zhu@i-mabbiopharma.com<\/span><\/a><\/span><\/u><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+86 21 6057 8000<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><\/span>&nbsp;<\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><\/span>&nbsp;<\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u51af\u7426\uff0c\u9996\u5e2d\u4f20\u64ad\u5b98<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><u><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:gigi.feng@i-mabbiopharma.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\"><span class=\"prnews_span\">gigi.feng@i-mabbiopharma.com<\/span><\/a><\/span><\/u><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+86 21 6057 5785<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><\/span>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p><b><span>\u6295\u8d44\u8005\u54a8\u8be2<\/span><\/b><\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><i><span class=\"prnews_span\">Burns McClellan, Inc. (<\/span><\/i><i><span class=\"prnews_span\">\u7f8e\u56fd\u548c\u6b27\u6d32<\/span><\/i><i><span class=\"prnews_span\">)<\/span><\/i><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">Steve Klass<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:sklass@burnsmc.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\">sklass@burnsmc.com<\/a><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+1 212 213 0006<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><i><span class=\"prnews_span\">The Piacente Group, Inc.&nbsp;(<\/span><\/i><i><span class=\"prnews_span\">\u4e9a\u6d32\uff09<\/span><\/i><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">Emilie Wu<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:emilie@thepiacentegroup.com\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\">emilie@thepiacentegroup.com<\/a><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"tel:+86%2021%206039%208363\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\"><span class=\"prnews_span\">+86 21 6039 8363<\/span><\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>&nbsp;<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder2\">  <\/div>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>http:\/\/www.i-mabbiopharma.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5355\u836f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u8bc1\u5b9e lemzoparlimab\u5177\u6709\u5dee\u5f02\u5316\u7684\u5b89\u5168\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66\u4f18\u52bf \u5176\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6076\u6027\u80bf\u7624\u521d\u6b65\u663e\u793a\u7597\u6548\u4fe1\u53f7 \u5929\u5883\u751f\u7269\u5c06\u4e8e\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f411\u67089\u65e5\u65e9\u4e0a8:30\u53ec\u5f00\u6295\u8d44\u8005\u7535\u8bdd\u4f1a\u8bae \u4e2d\u56fd\u4e0a\u6d77\u548c\u7f8e\u56fd\u76d6\u745f\u65af\u58212020\u5e7411\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u5929\u5883\u751f\u7269\uff08\u201c\u516c\u53f8\u201d\uff09\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aIMAB\uff09\u662f\u4e00\u5bb6\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u521b\u65b0\u751f\u7269\u836f\u7684\u9776\u70b9\u53d1\u73b0\u3001\u4e34\u5e8a\u5f00\u53d1\u548c\u4ea7\u54c1\u5546\u4e1a\u5316\uff0c\u4e3a\u5168\u7403\u8303\u56f4\u5185\u6cbb\u7597\u9700\u6c42\u8feb\u5207\u7684\u764c\u75c7\u6cbb\u7597\u9886\u57df\uff0c\u63d0\u4f9b\u65b0\u578b\u6709\u6548\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u516c\u53f8\u4eca\u5929\u5728\u7b2c35\u5c4a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u5b66\u4f1a\u5e74\u4f1a\uff08SITC 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