{"id":90945,"date":"2023-08-08T11:43:00","date_gmt":"2023-08-08T04:43:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023080811430090945"},"modified":"2023-08-08T15:24:54","modified_gmt":"2023-08-08T07:24:54","slug":"%e5%86%8d%e9%bc%8e%e5%8c%bb%e8%8d%af%e5%85%ac%e5%b8%832023%e5%b9%b4%e7%ac%ac%e4%ba%8c%e5%ad%a3%e5%ba%a6%e8%b4%a2%e5%8a%a1%e4%b8%9a%e7%bb%a9%e5%92%8c%e5%85%ac%e5%8f%b8%e8%bf%9b%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023080811430090945","title":{"rendered":"\u518d\u9f0e\u533b\u836f\u516c\u5e032023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u8d22\u52a1\u4e1a\u7ee9\u548c\u516c\u53f8\u8fdb\u5c55"},"content":{"rendered":"<ul type=\"disc\">\n<li><i>2023<\/i><i>\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u4ea7\u54c1\u6536\u5165\u5408\u8ba1\u4e3a<\/i><i>6,890<\/i><i>\u4e07\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f<\/i><i>45%<\/i><i>\uff1b\u6309\u56fa\u5b9a\u6c47\u7387\u8ba1\u7b97\u540c\u6bd4\u589e\u957f<\/i><i>53%<\/i><\/li>\n<li><i>\u536b\u4f1f\u8fe6<\/i><i><sup>&reg;<\/sup><\/i><i>\uff08\u827e\u52a0\u83ab\u5fb7<\/i><i>\u03b1<\/i><i>\u6ce8\u5c04\u6db2\uff09\u6210\u4e3a\u5728\u4e2d\u56fd\u83b7\u6279\u7684\u9996\u4e2a\u4e14\u76ee\u524d\u552f\u4e00\u7684\u65b0\u751f\u513f<\/i><i>Fc<\/i><i>\u53d7\u4f53\uff08<\/i><i>FcRn<\/i><i>\uff09\u62ee\u6297\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u5168\u8eab\u578b\u91cd\u75c7\u808c\u65e0\u529b\uff08<\/i><i>gMG<\/i><i>\uff09\uff1b<\/i> <i>\u5546\u4e1a\u5316\u4e0a\u5e02\u51c6\u5907\u5de5\u4f5c\u6b63\u5728\u8fdb\u884c\u4e2d\uff1b<\/i> <i>\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5242\u578b\u7528\u4e8e\u6cbb\u7597<\/i><i> gMG<\/i><i>\u7684\u751f\u7269\u5236\u54c1\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7<\/i><i>(BLA)\u6b63\u5728\u5ba1\u8bc4\u4e2d<\/i><\/li>\n<li><i>VYVGART Hytrulo<\/i><i>\uff08<\/i><i>efgartigimod alfa <\/i><i>\u548c\u900f\u660e\u8d28\u9178\u9176<\/i><i>-qvfc<\/i><i>\uff09\u7528\u4e8e\u6cbb\u7597\u6162\u6027\u708e\u6027\u8131\u9ad3\u9798\u6027\u591a\u53d1\u6027\u795e\u7ecf\u6839\u795e\u7ecf\u75c5<\/i><i> (CIDP)<\/i><i>\u7684\u4e34\u5e8a\u7814\u7a76<\/i><i> ADHERE<\/i><i>\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9<\/i><\/li>\n<li><i>\u7a33\u5065\u7684\u8d44\u4ea7\u8d1f\u503a\u72b6\u51b5\uff0c\u622a\u81f3<\/i><i>2023<\/i><i>\u5e74<\/i><i>6<\/i><i>\u6708<\/i><i>30<\/i><i>\u65e5\u73b0\u91d1\u50a8\u5907\u4e3a<\/i><i>8.764<\/i><i>\u4ebf\u7f8e\u5143\uff0c\u622a\u81f3<\/i><i>2023<\/i><i>\u5e74<\/i><i>3<\/i><i>\u6708<\/i><i>31<\/i><i>\u65e5\u7684\u73b0\u91d1\u50a8\u5907\u4e3a<\/i><i>9.314<\/i><i>\u4ebf\u7f8e\u5143<\/i><\/li>\n<li><i>\u516c\u53f8\u5c06\u4e8e\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f4<\/i><i> 2023 <\/i><i>\u5e74<\/i><i> 8 <\/i><i>\u6708<\/i><i> 8 <\/i><i>\u65e5\u4e0a\u5348<\/i><i> 8:00<\/i><i>\uff08\u5317\u4eac\u65f6\u95f4<\/i><i>8\u67088\u65e5\u665a20:00\uff09\u4e3e\u884c\u7535\u8bdd\u4f1a\u8bae\u548c\u7f51\u7edc\u76f4\u64ad<\/i><\/li>\n<\/ul>\n<p><p><span class=\"legendSpanClass\">\u4e2d\u56fd\u4e0a\u6d77\u548c\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865<\/span><span class=\"legendSpanClass\">2023\u5e748\u67088\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u518d\u9f0e\u533b\u836f\u6709\u9650\u516c\u53f8\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aZLAB\uff1b\u9999\u6e2f\u8054\u4ea4\u6240\u80a1\u4efd\u4ee3\u53f7\uff1a9688\uff09\uff0c\u4eca\u65e5\u516c\u5e03\u4e86 2023 \u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684\u8d22\u52a1\u4e1a\u7ee9\uff0c\u4ee5\u53ca\u8fd1\u671f\u7684\u4ea7\u54c1\u4eae\u70b9\u548c\u516c\u53f8\u8fdb\u5c55\u3002<\/p>\n<p>\u518d\u9f0e\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u675c\u83b9\u535a\u58eb\u8868\u793a\uff1a&quot;2023 \u5e74\u7b2c\u4e8c\u5b63\u5ea6\uff0c\u6211\u4eec\u7ee7\u7eed\u6210\u529f\u63a8\u8fdb\u5404\u9879\u4e1a\u52a1\u3002 \u6211\u4eec\u7684\u5546\u4e1a\u5316\u4ea7\u54c1\u4fdd\u6301\u5f3a\u52b2\u589e\u957f\uff0c\u6309\u56fa\u5b9a\u6c47\u7387\u8ba1\u7b97\uff0c\u4ea7\u54c1\u51c0\u6536\u5165\u589e\u957f\u4e86 53%\uff0c\u540c\u65f6\u6211\u4eec\u5728\u591a\u4e2a\u540e\u671f\u5f00\u53d1\u9879\u76ee\u548c\u65e9\u671f\u4ea7\u54c1\u7ba1\u7ebf\u90fd\u53d6\u5f97\u4e86\u91cd\u8981\u8fdb\u5c55\u3002\u6700\u4e3a\u91cd\u8981\u7684\u662f\uff0c\u6211\u4eec\u7684\u536b\u4f1f\u8fe6\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u4e0a\u5e02\uff0c\u4f5c\u4e3a\u4e00\u6b3e\u540c\u7c7b\u9996\u521b\u7684\u7597\u6cd5\uff0c\u5b83\u6709\u671b\u663e\u8457\u6539\u53d8\u4e2d\u56fd\u7f79\u60a3 gMG \u60a3\u8005\u7684\u751f\u6d3b\uff0c\u6211\u4eec\u5728 6 \u6708 30 \u65e5\u8fbe\u6210\u4e86\u8fd9\u4e00\u91cd\u5927\u91cc\u7a0b\u7891\u4e8b\u4ef6\uff0c\u8fd9\u4f7f\u5f97\u6211\u4eec\u6709\u8d44\u683c\u53c2\u4e0e2024\u5e74\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\u8c08\u5224\u3002\u8fd1\u671f\u827e\u52a0\u83ab\u5fb7\u7528\u4e8eCIDP\u6cbb\u7597\u53d6\u5f97\u7684\u9633\u6027\u7814\u7a76\u6570\u636e\uff0c\u8ba9\u6211\u4eec\u5bf9\u5176\u5728\u591a\u4e2a\u9002\u5e94\u8bc1\u9886\u57df\u6210\u4e3a\u6f5c\u5728\u91cd\u78c5\u836f\u7269\u5145\u6ee1\u4fe1\u5fc3\u3002&quot;<\/p>\n<p>\u518d\u9f0e\u533b\u836f\u603b\u88c1\u517c\u9996\u5e2d\u8fd0\u8425\u5b98 <span class=\"xn-person\">Josh Smiley<\/span> \u8868\u793a\uff1a&quot;\u5c55\u671b\u672a\u6765\uff0c\u518d\u9f0e\u533b\u836f\u5728\u672a\u6765\u4e94\u5e74\u5185\u6709\u671b\u5b9e\u73b0\u6536\u5165\u7684\u5927\u5e45\u589e\u957f\u548c\u5229\u6da6\u7387\u7684\u63d0\u5347\u3002\u6b63\u5982\u6211\u4eec\u5728 2023\u5e74\u6295\u8d44\u8005\u65e5\u6d3b\u52a8\u4e0a\u6240\u5f3a\u8c03\u7684\uff0c\u518d\u9f0e\u9884\u8ba1\u52302028\u5e74\u5e95\u5c06\u62e5\u6709\u8d85\u8fc715\u4e2a\u5546\u4e1a\u5316\u9636\u6bb5\u4ea7\u54c1\uff0c\u5e76\u4e14\u6bcf\u5e74\u81f3\u5c11\u63d0\u4ea4\u4e00\u4e2a\u6f5c\u5728\u540c\u7c7b\u9996\u521b\/\u540c\u7c7b\u6700\u4f18\u4ea7\u54c1\u7ba1\u7ebf\u7684\u65b0\u836f\u4e34\u5e8a\u7814\u7a76\u7533\u8bf7\u3002\u9884\u8ba1\u4ece2023\u5e74\u52302028\u5e74\uff0c\u6211\u4eec\u5f3a\u5927\u7684\u7ba1\u7ebf\u8d44\u4ea7\u5c06\u63a8\u52a8\u516c\u53f8\u4fdd\u6301\u8d85\u8fc750%\u7684\u5e74\u5747\u590d\u5408\u589e\u957f\u7387\u3002\u5728\u63a8\u51fa\u65b0\u4ea7\u54c1\u548c\u9002\u5e94\u8bc1\u7684\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u5c06\u7ee7\u7eed\u4fdd\u6301\u5ba1\u614e\u548c\u8d44\u672c\u6548\u7387\uff0c\u4f18\u5316\u6211\u4eec\u7684\u7814\u53d1\u5de5\u4f5c\u5e76\u63d0\u5347\u5168\u516c\u53f8\u751f\u4ea7\u529b\u3002\u6211\u4eec\u9884\u8ba1\uff0c\u5728\u8fd9\u4e00\u63aa\u65bd\u548c\u9884\u671f\u6536\u5165\u589e\u957f\u7684\u53cc\u91cd\u9a71\u52a8\u4e0b\uff0c\u52302025\u5e74\u5e74\u5e95\u6211\u4eec\u6709\u671b\u5b9e\u73b0\u516c\u53f8\u76c8\u5229\u3002&quot;<\/p>\n<p><b>\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\u548c\u516c\u53f8\u8fdb\u5c55<\/b><\/p>\n<p>\u518d\u9f0e\u533b\u836f\u5df2\u7ecf\u5efa\u7acb\u4e86\u5dee\u5f02\u5316\u7684\u4ea7\u54c1\u548c\u7ba1\u7ebf\u7ec4\u5408\uff0c\u5176\u4e2d\u5305\u62ec13\u9879\u5904\u4e8e\u540e\u671f\u5f00\u53d1\u9636\u6bb5\u7684\u7ba1\u7ebf\u3002\u81ea\u4e0a\u6b21\u8d22\u62a5\u53d1\u5e03\u4ee5\u6765\uff0c\u6211\u4eec\u5728\u4ea7\u54c1\u548c\u5019\u9009\u4ea7\u54c1\u65b9\u9762\u53d6\u5f97\u8bf8\u591a\u4ee4\u4eba\u5174\u594b\u7684\u8fdb\u5c55\uff0c\u5176\u4e2d\u5305\u62ec\uff1a<\/p>\n<p><b>\u5546\u4e1a\u5316\u4ea7\u54c1<\/b><\/p>\n<p><i>\u5728\u5219\u4e50<\/i><sup>&reg;<\/sup><i>\u3001\u64ce\u4e50<\/i><sup>&reg;<\/sup><i>\u548c\u7ebd\u518d\u4e50<\/i><sup>&reg;<\/sup><i>\u5747\u88ab\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\uff08\u533b\u4fdd\u76ee\u5f55\uff09\u4ee5\u53ca\u7231\u666e\u76fe<\/i><sup>&reg;<\/sup><i>\u88ab\u7eb3\u5165\u66f4\u591a\u8865\u5145\u4fdd\u9669\u8ba1\u5212\u7684\u63a8\u52a8\u4e0b\uff0c<\/i><i>2023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u6211\u4eec\u6bcf\u6b3e\u5546\u4e1a\u5316\u4ea7\u54c1\u7684\u9500\u552e\u989d\u76f8\u8f832022\u5e74\u540c\u671f\uff0c\u5747\u4fdd\u6301\u589e\u957f\u3002<\/i><\/p>\n<p>\u57282023 \u5e74\u7b2c\u4e8c\u5b63\u5ea6\uff0c\u6211\u4eec\u7684\u5546\u4e1a\u5316\u4ea7\u54c1\u8fd8\u53d6\u5f97\u4e86\u4ee5\u4e0b\u6ce8\u518c\u6279\u51c6:<\/p>\n<ul type=\"disc\">\n<li><b>\u536b\u4f1f\u8fe6<\/b><sup>&reg;<\/sup>\uff1a\u536b\u4f1f\u8fe6\u662f\u4e00\u6b3e\u540c\u7c7b\u9996\u521b\u7684FcRn\u62ee\u6297\u5242\u30022023\u5e746\u6708\uff0c NMPA\u6279\u51c6\u536b\u4f1f\u8fe6\uff08\u827e\u52a0\u83ab\u5fb7\u03b1\u6ce8\u5c04\u6db2\uff09\u7684BLA\uff0c\u4e0e\u6807\u51c6\u6cbb\u7597\u836f\u7269\u8054\u5408\uff0c\u7528\u4e8e\u6cbb\u7597\u4e59\u9170\u80c6\u78b1\u53d7\u4f53\uff08AChR\uff09\u6297\u4f53\u9633\u6027\u7684\u6210\u4ebagMG\u60a3\u8005\u3002\u6211\u4eec\u9884\u8ba1\u4eca\u5e74\u665a\u4e9b\u65f6\u5019\u536b\u4f1f\u8fe6\u5c06\u5728\u4e2d\u56fd\u5185\u5730\u5546\u4e1a\u5316\u4e0a\u5e02\u3002<\/li>\n<li><b>\u7231\u666e\u76fe<\/b>\uff1a2023\u5e745\u6708\uff0c \u4e2d\u56fd\u53f0\u6e7e\u5730\u533a\u836f\u68b0\u5ba1\u6279\u90e8\u95e8\u6279\u51c6\u80bf\u7624\u7535\u573a\u6cbb\u7597\u7231\u666e\u76fe\u7528\u4e8e\u6cbb\u7597\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\uff08GBM\uff09\u60a3\u8005\u7684\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\u3002<\/li>\n<\/ul>\n<p><b>\u5173\u952e\u5019\u9009\u4ea7\u54c1\u8fdb\u5c55<\/b><\/p>\n<p><i>\u6211\u4eec\u901a\u8fc7\u7814\u53d1\u548c\u5546\u4e1a\u5316\u8fd0\u8425\u6301\u7eed\u63a8\u8fdb\u6211\u4eec\u7684\u5019\u9009\u4ea7\u54c1\uff0c\u5305\u62ec\u4ee5\u4e0b\u4e34\u5e8a\u7814\u7a76\u3001\u6ce8\u518c\u5ba1\u6279\u65b9\u9762\u7684\u8fdb\u5c55\uff1a<\/i><\/p>\n<p><b><i>\u80bf\u7624\u9886\u57df<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u5219\u4e50<\/b><b>(<\/b><b>\u5c3c\u62c9\u5e15\u5229<\/b><b>, PARP)<\/b>\uff1a2023 \u5e74 7 \u6708\uff0cJAMA Oncology\u53d1\u8868\u4e863\u671f\u4e34\u5e8a\u7814\u7a76PRIME\u7684\u7814\u7a76\u6570\u636e\uff0c\u652f\u6301\u4e86\u5219\u4e50\u4f5c\u4e3a\u4e2d\u56fd\u66f4\u5e7f\u6cdb\u7684\u65b0\u8bca\u65ad\u665a\u671f\u5375\u5de2\u764c\u60a3\u8005\u7ef4\u6301\u6cbb\u7597\u7684\u5e94\u7528\uff0c\u5e76\u8bc1\u660e\u4e86\u76f8\u8f83300mg\u56fa\u5b9a\u8d77\u59cb\u5242\u91cf\uff0c\u57fa\u4e8e\u57fa\u7ebf\u4f53\u91cd\u548c\u8840\u5c0f\u677f\u8ba1\u6570\u91c7\u7528\u5219\u4e50200mg\u6216300mg\u7684\u4e2a\u4f53\u5316\u8d77\u59cb\u5242\u91cf\uff0c\u80fd\u591f\u4e3a\u60a3\u8005\u5e26\u6765\u663e\u8457\u4e34\u5e8a\u83b7\u76ca\u4e14\u63d0\u5347\u4e86\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u3002\u8fd9\u4e9b\u6570\u636e\u8868\u660e\uff0c\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0c\u63a5\u53d7\u5219\u4e50\u7ef4\u6301\u6cbb\u7597\u663e\u8457\u5ef6\u957f\u4e86\u60a3\u8005\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff0c\u4e14\u4f7f\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u4e8655%\u3002<\/li>\n<li><b>\u80bf\u7624\u7535\u573a\u6cbb\u7597\n<p><\/b>&#8211;&nbsp;<i>\u80f0\u817a\u764c<\/i>\uff1a2023\u5e747\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34NovoCure Limited\uff08NovoCure\uff09\u5ba3\u5e03\u6536\u5230\u6765\u81ea\u72ec\u7acb\u6570\u636e\u76d1\u5bdf\u59d4\u5458\u4f1a\u7684\u5efa\u8bae\uff0c\u652f\u6301\u7ee7\u7eed\u8fdb\u884c\u80bf\u7624\u7535\u573a\u6cbb\u7597\u7528\u4e8e\u80f0\u817a\u764c\u76843\u671f\u4e34\u5e8a\u7814\u7a76PANOVA-3\u3002\u9884\u5148\u6307\u5b9a\u7684\u4e2d\u671f\u5206\u6790\u5f97\u51fa\u7ed3\u8bba\uff0c\u5df2\u5b8c\u6210\u5165\u7ec4\u7684 PANOVA-3 \u4e34\u5e8a\u7814\u7a76\u5e94\u6309\u8ba1\u5212\u8fdb\u884c\u6700\u7ec8\u5206\u6790\u3002\u518d\u9f0e\u533b\u836f\u5728\u5927\u4e2d\u534e\u533a\u53c2\u4e0e\u4e86\u8be5\u7814\u7a76\u3002<\/p>\n<p>&#8211;&nbsp;<i>\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08<\/i><i>NSCLC\uff09\uff1a<\/i>2023\u5e746\u6708\uff0c\u518d\u9f0e\u533b\u836f\u548cNovoCure\u5ba3\u5e03\uff0c3\u671f\u4e34\u5e8a\u7814\u7a76LUNAR\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\uff0c\u8bc1\u5b9e\u4e3a\u63a5\u53d7\u94c2\u7c7b\u5316\u7597\u540e\u7684\u8f6c\u79fb\u6027NSCLC\u60a3\u8005\u5e26\u6765\u5177\u6709\u663e\u8457\u7edf\u8ba1\u5b66\u610f\u4e49\u548c\u4e34\u5e8a\u610f\u4e49\u7684\u603b\u751f\u5b58\u671f\u6539\u5584\u3002\u518d\u9f0e\u533b\u836f\u5728\u5927\u4e2d\u534e\u533a\u53c2\u4e0e\u4e86\u8be5\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p class=\"prnml80\">&#8211; \u4e0e\u6807\u51c6\u6cbb\u7597\u76f8\u6bd4\uff0c\u80bf\u7624\u7535\u573a\u6cbb\u7597\u8054\u5408\u6807\u51c6\u6cbb\u7597\u63d0\u4f9b\u4e86\u5177\u6709\u663e\u8457\u7edf\u8ba1\u5b66\u610f\u4e49\u548c\u4e34\u5e8a\u610f\u4e49\u7684\u8d85\u8fc73\u4e2a\u6708\u7684\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u6539\u5584\uff0c\u4e14\u672a\u589e\u52a0\u7cfb\u7edf\u6027\u6bd2\u6027\u3002<\/p>\n<p class=\"prnml80\">&#8211; \u80bf\u7624\u7535\u573a\u6cbb\u7597\u8054\u5408\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5728\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u65b9\u9762\u5b9e\u73b0\u524d\u6240\u672a\u6709\u7684\u63a5\u8fd18\u4e2a\u6708\u7684\u6539\u5584\u3002<\/p>\n<ul type=\"disc\">\n<li><b>KRAZATI&reg; (adagrasib, <\/b>KRAS<sup>G12C<\/sup><b>):<br \/><\/b>&#8211; 2023\u5e747\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5b8c\u6210\u4e86\u5168\u74033\u671f\u4e34\u5e8a\u7814\u7a76KRYSTAL-10\u5728\u4e2d\u56fd\u7684\u60a3\u8005\u5165\u7ec4\uff0c\u8be5\u7814\u7a76\u65e8\u5728\u8bc4\u4f30adagrasib\u8054\u5408\u897f\u59a5\u6614\u5355\u6297\u5bf9\u6bd4\u5316\u7597\uff0c\u7528\u4e8e\u7ecf\u6cbb\u7684\u665a\u671f&nbsp;&nbsp;KRAS<sup>G12C<\/sup>\u7a81\u53d8\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u3002\n<p>&#8211; 2023\u5e746\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5b8c\u6210\u4e86\u5168\u74032\u671f\u4e34\u5e8a\u7814\u7a76KRYSTAL-7 \u5728\u4e2d\u56fd\u7684\u60a3\u8005\u5165\u7ec4\u3002\u8be5\u7814\u7a76\u65e8\u5728\u8bc4\u4f30adagrasib\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u4e00\u7ebf\u6cbb\u7597\u665a\u671fKRAS<sup>G12C<\/sup>&nbsp;\u7a81\u53d8&nbsp;NSCLC \u60a3\u8005\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>\u745e\u666e\u66ff\u5c3c\uff08<\/b><b>ROS1\/TRK\uff09<\/b>\uff1a\u7ee72023\u5e745\u6708\u745e\u666e\u66ff\u5c3c\u88ab\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u540e\uff0c2023\u5e746\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5ba3\u5e03\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u53d7\u7406\u745e\u666e\u66ff\u5c3c\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7(NDA)\uff0c\u7528\u4e8e\u6cbb\u7597ROS1\u9633\u6027\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027NSCLC\u6210\u4eba\u60a3\u8005\u30022023 \u5e74 5 \u6708\uff0c\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d (BMS) \u5ba3\u5e03\uff0c\u745e\u666e\u66ff\u5c3c\u7528\u4e8e\u540c\u6837\u9002\u5e94\u8bc1\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u5df2\u83b7\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09 \u53d7\u7406\uff0c\u5e76\u88ab\u6388\u4e88\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\uff0c\u5904\u65b9\u836f\u7528\u6237\u4ed8\u8d39\u6cd5\u6848 (PDUFA) \u76ee\u6807\u884c\u52a8\u65e5\u671f\u4e3a 2023 \u5e74 11\u6708 27 \u65e5\u3002<\/li>\n<li><b>Bemarituzumab (FGFR2b)<\/b>\uff1a2023 \u5e74 7 \u6708\uff0c\u518d\u9f0e\u533b\u836f\u5b8c\u6210\u5168\u74033\u671f\u4e34\u5e8a\u7814\u7a76 FORTITUDE-101 \u7684\u4e2d\u56fd\u5185\u5730\u9996\u4f8b\u60a3\u8005\u5165\u7ec4\uff0c\u8be5\u7814\u7a76\u65e8\u5728\u8bc4\u4f30bemarituzumab\u8054\u5408\u5316\u7597\uff0c\u5bf9\u6bd4\u5b89\u6170\u5242\u8054\u5408\u5316\u7597\uff0c\u7528\u4e8eFGFR2b \u8fc7\u5ea6\u8868\u8fbe\u7684\u80c3\u764c\u4e00\u7ebf\u6cbb\u7597\u3002<\/li>\n<\/ul>\n<p><b><i>\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9886\u57df<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u536b\u4f1f\u8fe6\uff08\u827e\u52a0\u83ab\u5fb7\uff0c<\/b><b>FcRn<\/b><b>\uff09\n<p><\/b>&#8211; gMG\uff1a2023\u5e746\u6708\uff0cargenx BV\uff08argenx\uff09\u5ba3\u5e03FDA\u6279\u51c6VYVGART Hytrulo\uff08efgartigimod alfa \u548c\u900f\u660e\u8d28\u9178\u9176-qvfc\uff09\u6ce8\u5c04\u6db2\u7528\u4e8egMG\u76ae\u4e0b\u6ce8\u5c04\u30022023\u5e747\u6708\uff0c NMPA\u53d7\u7406\u4e86\u518d\u9f0e\u533b\u836f\u63d0\u4ea4\u7684\u827e\u52a0\u83ab\u5fb7\u03b1\u6ce8\u5c04\u6db2\uff08\u76ae\u4e0b\u6ce8\u5c04\uff09\u7528\u4e8e\u6cbb\u7597\u6210\u4ebagMG\u60a3\u8005\u7684BLA\u3002<\/p>\n<p>&#8211; CIDP\uff1a2023 \u5e74 7 \u6708\uff0c\u518d\u9f0e\u533b\u836f\u548c\u5408\u4f5c\u4f19\u4f34argenx \u516c\u5e03\u4e86VYVGART Hytrulo\u7528\u4e8e\u6210\u4ebaCIDP\u60a3\u8005\u7684\u5168\u7403\u6ce8\u518c\u6027\u7814\u7a76ADHERE\u7684\u9633\u6027\u4e3b\u8981\u6570\u636e\u3002 \u518d\u9f0e\u533b\u836f\u5728\u5927\u4e2d\u534e\u533a\u53c2\u4e0e\u4e86\u8be5\u7814\u7a76\u3002\u7814\u7a76\u7ed3\u679c\u4eae\u70b9\u5305\u62ec\uff1a<\/li>\n<\/ul>\n<p class=\"prnml80\">&#8211; \u8fbe\u5230\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9 (p=0.000039)\uff1b\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0cVYVGART Hytrulo \u53ef\u964d\u4f4e\u590d\u53d1\u98ce\u966961% (HR: 0.39 95% CI: 0.25; 0.61)\uff1b<\/p>\n<p class=\"prnml80\">&#8211; \u5728\u5f00\u653e\u6807\u7b7eA\u9636\u6bb5\uff0c67%\u7684\u60a3\u8005\u786e\u8ba4\u51fa\u73b0\u4e34\u5e8a\u6539\u5584\uff08ECI\uff09\uff0c\u8868\u660eIgG\u81ea\u8eab\u6297\u4f53\u5728CIDP\u7684\u751f\u7269\u5b66\u673a\u5236\u4e2d\u53d1\u6325\u7740\u91cd\u8981\u4f5c\u7528\u3002<\/p>\n<p class=\"prnml80\">&#8211; \u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u4e0e\u6b64\u524d\u7684\u4e34\u5e8a\u7814\u7a76\u548c\u5df2\u786e\u8ba4\u7684\u536b\u4f1f\u8fe6\u7684\u5b89\u5168\u6027\u7279\u5f81\u4e00\u81f4\u3002<\/p>\n<p class=\"prnml40\">&#8211; \u5927\u75b1\u6027\u7c7b\u5929\u75b1\u75ae\uff08BP\uff09\uff1a2023\u5e745\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5728\u4e2d\u56fd\u5165\u7ec4\u4e86\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5242\u578b\u7528\u4e8e\u6210\u4ebaBP\u60a3\u8005\u7684\u5168\u7403\u60272\/3\u671f\u7814\u7a76BALLAD\u4e2d\u7684\u9996\u4f8b\u60a3\u8005\u3002<\/p>\n<ul type=\"disc\">\n<li>XACDURO&reg;\uff08\u8212\u5df4\u5766\u94a0-\u5ea6\u6d1b\u5df4\u5766\u94a0\uff0c\u4e9a\u592a\u533a\u6743\u76ca\uff09\uff1a2023\u5e745\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34\u3001Innoviva\u7684\u5168\u8d44\u5b50\u516c\u53f8Entasis Therapeutics, Inc. (Entasis)\u5ba3\u5e03FDA\u6279\u51c6XACDURO\u7528\u4e8e\u6cbb\u7597\u7531\u9c8d\u66fc\u4e0d\u52a8\u6746\u83cc-\u918b\u9178\u9499\u4e0d\u52a8\u6746\u83cc\u590d\u5408\u4f53\uff08\u4e0d\u52a8\u6746\u83cc\uff09\u7684\u654f\u611f\u83cc\u682a\u5f15\u8d77\u7684\u533b\u9662\u83b7\u5f97\u6027\u7ec6\u83cc\u6027\u80ba\u708e\u548c\u547c\u5438\u673a\u76f8\u5173\u6027\u7ec6\u83cc\u6027\u80ba\u708e \uff08HABP\/VABP\uff09\u6210\u4eba\u60a3\u8005\u3002\u5728\u4e2d\u56fd\uff0cNMPA\u6b63\u5728\u5ba1\u8bc4\u516c\u53f8\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff0c\u5e76\u5df2\u6388\u4e88\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\u3002\n<\/li>\n<li>KarXT\uff08xanomeline-trospium\uff0cM1\/M4\u578b\u6bd2\u8548\u78b1\u4e59\u9170\u80c6\u78b1\u53d7\u4f53\u6fc0\u52a8\u5242\uff09\uff1a2023 \u5e74 6 \u6708\uff0c\u518d\u9f0e\u533b\u836f\u5728\u4e2d\u56fd\u5185\u5730\u5165\u7ec4\u4e86\u8bc4\u4f30 KarXT \u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u6ce8\u518c\u6027\u6865\u63a5\u7814\u7a76\u7684\u9996\u4f8b\u60a3\u8005\u3002<\/li>\n<\/ul>\n<p><b>\u516c\u53f8\u8fdb\u5c55<\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u7ec4\u7ec7\u66f4\u65b0<\/b>\uff1a2023 \u5e74 7 \u6708\uff0c\u518d\u9f0e\u533b\u836f\u664b\u5347\u9648\u5a05\u9759\u535a\u58eb\u4e3a\u9996\u5e2d\u8d22\u52a1\u5b98 (CFO)\uff0c\u81ea 2023 \u5e74 7 \u6708 7 \u65e5\u8d77\u751f\u6548\u3002\u6b64\u524d\uff0c\u9648\u535a\u58eb\u81ea2021\u5e749\u6708\u52a0\u5165\u516c\u53f8\u4ee5\u6765\u62c5\u4efb\u516c\u53f8\u9ad8\u7ea7\u526f\u603b\u88c1\u517c\u526f\u9996\u5e2d\u8d22\u52a1\u5b98\uff0c\u5e2e\u52a9\u7ba1\u7406\u8d22\u52a1\u3001\u9884\u7b97\u3001\u4f1a\u8ba1\u3001\u7a0e\u52a1\u3001\u8d44\u91d1\u548c\u91c7\u8d2d\u76f8\u5173\u5de5\u4f5c\u3002\u5979\u662f\u4e00\u4f4d\u8d44\u6df1\u7684\u8d22\u52a1\u9886\u5bfc\u8005\uff0c\u5728\u751f\u547d\u79d1\u5b66\u9886\u57df\u62e5\u6709\u8d85\u8fc720\u5e74\u7684\u884c\u4e1a\u7ecf\u9a8c\uff0c\u540c\u65f6\u4e5f\u662f\u4e00\u4f4d\u63a5\u53d7\u8fc7\u535a\u58eb\u8bad\u7ec3\u7684\u79d1\u5b66\u5bb6\u3002 \u52a0\u5165\u518d\u9f0e\u533b\u836f\u524d\uff0c\u5979\u4ece 2006 \u5e74\u81f3 2021 \u5e74\u671f\u95f4\u5728\u963f\u65af\u5229\u5eb7\u5de5\u4f5c\u5e76\u62c5\u4efb\u8fc7\u591a\u4e2a\u804c\u52a1\uff0c\u804c\u8d23\u4e0d\u65ad\u589e\u52a0\uff0c\u5305\u62ec 2019 \u5e74\u81f3 2021 \u5e74\u62c5\u4efb\u963f\u65af\u5229\u5eb7\u7f8e\u56fd\u80bf\u7624\u4e1a\u52a1\u90e8\u9996\u5e2d\u8d22\u52a1\u5b98\u4ee5\u53ca 2016 \u5e74\u81f3 2019 \u5e74\u62c5\u4efb\u963f\u65af\u5229\u5eb7\u5168\u7403\u80bf\u7624\u4e1a\u52a1\u90e8\u8d22\u52a1\u603b\u76d1\u3002\u5979\u7684\u79d1\u5b66\u80cc\u666f\uff0c\u7ed3\u5408\u5979\u4e30\u5bcc\u7684\u6267\u884c\u7ba1\u7406\u7ecf\u9a8c\u3001\u5728\u5168\u7403\u9886\u5148\u516c\u53f8\u7684\u8d22\u52a1\u4e13\u4e1a\u77e5\u8bc6\u548c\u654f\u9510\u7684\u5546\u4e1a\u6d1e\u5bdf\uff0c\u5c06\u4e3a\u518d\u9f0e\u533b\u836f\u5e26\u6765\u72ec\u7279\u7684\u89c6\u89d2\uff0c\u52a9\u529b\u63a8\u52a8\u516c\u53f8\u672a\u6765\u7684\u53d1\u5c55\u3002 \u9648\u535a\u58eb\u63a5\u4efb\u66f9\u57fa\u54f2\u5148\u751f\uff0c\u66f9\u57fa\u54f2\u5148\u751f\u5df2\u4e8e 2023 \u5e74 7 \u6708 7 \u65e5\u79bb\u4efb\u3002\n<\/li>\n<li><b>2023<\/b><b>\u5e74\u6295\u8d44\u8005\u65e5\u6d3b\u52a8<\/b>\uff1a\u518d\u9f0e\u533b\u836f\u4e8e2023\u5e746\u670820\u65e5\u5728\u7f8e\u56fd\u7ebd\u7ea6\u4e3e\u529e\u4e86\u6295\u8d44\u8005\u65e5\u6d3b\u52a8<br \/>&#8211; \u518d\u9f0e\u533b\u836f\u516c\u5e03\u4e86 5 \u5e74\u589e\u957f\u89c4\u5212\uff0c\u5305\u62ec\u5230 2028 \u5e74\u5e95\u5b9e\u73b0\u4ee5\u4e0b\u76ee\u6807<\/li>\n<\/ul>\n<p class=\"prnml80\">&#8211; \u52302028\u5e74\u62e5\u6709\u8d85\u8fc715\u6b3e\u5546\u4e1a\u5316\u9636\u6bb5\u4ea7\u54c1\uff08\u76ee\u524d\u62e5\u67095\u6b3e\uff09<\/p>\n<p class=\"prnml80\">&#8211; \u52302028\u5e74\u62e5\u6709\u8d85\u8fc78\u6b3e\u5177\u6709\u5168\u7403\u6743\u5229\u7684\u8fdb\u5165\u4e34\u5e8a\u9636\u6bb5\u7684\u7ba1\u7ebf\uff08\u76ee\u524d\u62e5\u67093\u6b3e\uff09\uff0c\u5e76\u4e14\u6bcf\u5e74\u81f3\u5c11\u63d0\u4ea41\u9879\u65b0\u836f\u4e34\u5e8a\u7814\u7a76\u7533\u8bf7\uff08IND\uff09<\/p>\n<p class=\"prnml80\">&#8211; 2023\u5e74\u81f32028\u5e74\u95f4\u4fdd\u630150%\u4ee5\u4e0a\u7684\u8425\u6536\u590d\u5408\u5e74\u589e\u957f\u7387<\/p>\n<p class=\"prnml80\">&#8211; \u5b9e\u73b0\u6536\u5165\u663e\u8457\u589e\u957f\u548c\u8425\u4e1a\u5229\u6da6\u7387\u6301\u7eed\u63d0\u5347\uff0c\u5230 2025 \u5e74\u5e74\u5e95\u5b9e\u73b0\u516c\u53f8\u76c8\u5229<\/p>\n<p class=\"prnml40\">&#8211; \u6b64\u5916\uff0c\u518d\u9f0e\u533b\u836f\u91cd\u70b9\u5c55\u793a\u4e86\u4ee5\u827e\u52a0\u83ab\u5fb7\u4e3a\u9996\u4e2a\u7684\u591a\u4e2a\u9500\u552e\u5cf0\u503c\u53ef\u80fd\u8d85\u8fc7 10 \u4ebf\u7f8e\u5143\u7684\u5173\u952e\u4ea7\u54c1\u3002<\/p>\n<p><b><i>2023<\/i><\/b><b><i>\u5e74\u9884\u671f\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/i><\/b><\/p>\n<p><b><i>\u80bf\u7624\u9886\u57df<\/i><\/b><\/p>\n<p><b>\u80bf\u7624\u7535\u573a\u6cbb\u7597<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34NovoCure \u5c06\u516c\u5e03\u5168\u7403\u5173\u952e\u6027\u4e34\u5e8a\u7814\u7a76INNOVATE-3\u7684\u4e3b\u8981\u6570\u636e\u89e3\u8bfb\uff0c\u8be5\u7814\u7a76\u65e8\u5728\u8bc4\u4f30\u80bf\u7624\u7535\u573a\u6cbb\u7597\u8054\u5408\u7d2b\u6749\u9187\u6cbb\u7597\u94c2\u8010\u836f\u5375\u5de2\u764c\u60a3\u8005\u7684\u7597\u6548\u3002<\/li>\n<\/ul>\n<p><b>KRAZATI (adagrasib, <\/b><b>KRAS<sup>G12C<\/sup><\/b><b>)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34 Mirati Therapeutics, Inc. (Mirati)\u5c06\u66f4\u65b0adagrasib\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u7528\u4e8e\u6cbb\u7597\u643a\u5e26KRAS<sup>G12C<\/sup>\u7a81\u53d8\u7684\u4e00\u7ebf NSCLC\u60a3\u8005\u7684\u5168\u7403 2 \u671f\u7814\u7a76 KRYSTAL-7\u7684\u4e34\u5e8a\u6570\u636e\u3002\u518d\u9f0e\u533b\u836f\u6b63\u5728\u5927\u4e2d\u534e\u533a\u53c2\u4e0e\u8be5\u4e34\u5e8a\u7814\u7a76\u3002<\/li>\n<li>Mirati \u5c06\u516c\u5e03\u901a\u8fc7\u591a\u79cd\u7814\u53d1\u8def\u5f84\u5f00\u5c55\u9488\u5bf9\u4e00\u7ebf<b>KRAS<sup>G12C<\/sup><\/b>\u7a81\u53d8NSCLC\u7684\u4e34\u5e8a\u5f00\u53d1\u8ba1\u5212\u7684\u8fdb\u5c55\u3002<\/li>\n<li>Mirati \u5c06\u5411 FDA \u63d0\u4ea4\u7528\u4e8e\u6cbb\u7597\u4e09\u7ebf\u53ca\u4ee5\u4e0a<b>KRAS<sup>G12C<\/sup><\/b>\u7a81\u53d8\u7684\u665a\u671f\u7ed3\u76f4\u80a0\u764c\uff08CRC\uff09\u60a3\u8005\u7684\u52a0\u901f\u5ba1\u6279\u8865\u5145\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08sNDA\uff09\u3002<\/li>\n<\/ul>\n<p><b>Odronextamab (CD20xCD3)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34\u518d\u751f\u5143\u5c06\u542f\u52a8\u7528\u4e8e\u6cbb\u7597\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff08FL\uff09\u548c\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\uff08\u5305\u62ec\u524d\u7ebf\u6cbb\u7597\uff09\u7684\u786e\u8bc1\u6027\u7814\u7a76\u3002<\/li>\n<li>\u518d\u751f\u5143\u9884\u8ba1\u5c06\u83b7\u5f97\u8be5\u836f\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u2571\u96be\u6cbb\u6027FL\u548cDLBCL\u7684BLA\u53ca\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\uff08MAA\uff09\u7684\u53d7\u7406\u3002<\/li>\n<\/ul>\n<p><b>\u9ea6\u7518\u4e50<\/b><b>&#x2122;<\/b><b>\uff08\u9a6c\u5409\u59a5\u6614\u5355\u6297\uff0c<\/b><b>HER2<\/b><b>\uff09<\/b><\/p>\n<ul type=\"disc\">\n<li>\u7528\u4e8e\u8f6c\u79fb\u6027HER2\u9633\u6027\u4e73\u817a\u764c\u60a3\u8005\u4e09\u7ebf\u53ca\u4ee5\u4e0a\u6cbb\u7597\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u6709\u671b\u83b7\u5f97NMPA\u6279\u51c6\u3002<\/li>\n<\/ul>\n<p><b><i>\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9886\u57df<\/i><\/b><\/p>\n<p>\u536b\u4f1f\u8fe6 (\u827e\u52a0\u83ab\u5fb7, FcRn)<\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34 argenx\u5c06\u4e8e2023 \u5e74\u7b2c\u56db\u5b63\u5ea6\u516c\u5e03\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5242\u578b\u7528\u4e8e\u6cbb\u7597\u5929\u75b1\u75ae\u7684\u6ce8\u518c\u6027 3 \u671f\u7814\u7a76ADDRESS\u548c\u7528\u4e8e\u6cbb\u7597\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08ITP\uff09\u7684\u6ce8\u518c\u60273 \u671f\u7814\u7a76ADVANCE-SC\u7684\u5173\u952e\u6027\u6570\u636e\u3002\u518d\u9f0e\u533b\u836f\u5728\u5927\u4e2d\u534e\u533a\u53c2\u4e0e\u4e86\u8fd9\u4e24\u9879\u7814\u7a76\u3002<\/li>\n<li>argenx\u5c06\u4e8e2023\u5e74\u7b2c\u56db\u5b63\u5ea6\u542f\u52a8\u827e\u52a0\u83ab\u5fb7\u6cbb\u7597\u7532\u72b6\u817a\u773c\u75c5\uff08TED\uff09\u7684\u6ce8\u518c\u6027\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b>KarXT (xanomeline-trospium<\/b><b>\uff0c<\/b><b>M1\/M4<\/b><b>\u578b\u6bd2\u8548\u78b1\u4e59\u9170\u80c6\u78b1\u53d7\u4f53\u6fc0\u52a8\u5242<\/b><b>)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34 Karuna \u5c06\u4e8e 2023 \u5e74\u7b2c\u4e09\u5b63\u5ea6\u5411 FDA \u63d0\u4ea4 KarXT \u7528\u4e8e\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002<\/li>\n<li>Karuna \u5c06\u542f\u52a8\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7cbe\u795e\u75c5\u6027\u969c\u788d\u76843 \u671f\u7814\u7a76 ADEPT-2\u548cADEPT-3\u3002 \u518d\u9f0e\u533b\u836f\u8ba1\u5212\u5728\u5927\u4e2d\u534e\u533a\u53c2\u4e0e\u76f8\u5173\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b><u>2023<\/u><\/b><b><u>\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u8d22\u52a1\u4e1a\u7ee9<\/u><\/b><\/p>\n<ul type=\"disc\">\n<li>2023 \u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684\u4ea7\u54c1\u6536\u5165\u4e3a 6,890 \u4e07\u7f8e\u5143\uff0c 2022 \u5e74\u540c\u671f\u4e3a 4,760 \u4e07\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f 45%\uff1b \u6309\u56fa\u5b9a\u6c47\u7387\u8ba1\u7b97\uff0c\u540c\u6bd4\u589e\u957f 53%\u3002 \u4ea7\u54c1\u6536\u5165\u589e\u52a0\u4e3b\u8981\u662f\u7531\u4e8e\u9500\u91cf\u589e\u52a0\u548c COVID-19\u75ab\u60c5\u8d1f\u9762\u5f71\u54cd\u7684\u51cf\u5c11\u5bfc\u81f4\u3002\u4e0e2022\u5e74\u540c\u671f\u76f8\u6bd4\uff0c2023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684\u4ea7\u54c1\u6536\u5165\u5305\u62ec\uff1a<\/li>\n<\/ul>\n<p class=\"prnml80\">&#8211; \u5219\u4e50\u4ea7\u54c1\u6536\u5165\u4e3a 4,300 \u4e07\u7f8e\u5143\uff0c\u8f832022 \u5e74\u540c\u671f\u7684 3,410 \u4e07\u7f8e\u5143\u589e\u957f 26%<\/p>\n<p class=\"prnml80\">&#8211; \u7231\u666e\u76fe\u4ea7\u54c1\u6536\u5165\u4e3a 1,370 \u4e07\u7f8e\u5143\uff0c\u8f832022 \u5e74\u540c\u671f\u7684&nbsp; 1,160 \u4e07\u7f8e\u5143\u589e\u957f\u4e86 18%<\/p>\n<p class=\"prnml80\">&#8211; \u64ce\u4e50\u4ea7\u54c1\u6536\u5165\u4ece2022 \u5e74\u540c\u671f\u768460\u4e07\u7f8e\u5143\u589e\u957f\u81f3750\u4e07\u7f8e\u5143<\/p>\n<p class=\"prnml80\">&#8211; \u7ebd\u518d\u4e50\u4ea7\u54c1\u6536\u5165\u4ece2022 \u5e74\u540c\u671f\u7684130\u4e07\u7f8e\u5143\u589e\u957f\u5230460\u4e07\u7f8e\u5143<\/p>\n<ul type=\"disc\">\n<li>2023 \u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684\u7814\u53d1 (R&amp;D) \u5f00\u652f\u4e3a 7,670 \u4e07\u7f8e\u5143\uff0c 2022 \u5e74\u540c\u671f\u4e3a 6,610 \u4e07\u7f8e\u5143\u3002\u7814\u53d1\u5f00\u652f\u7684\u589e\u957f\u4e3b\u8981\u662f\u7531\u4e8e\u7814\u7a76\u6d3b\u52a8\u7684\u589e\u52a0\u548c\u4e34\u5e8a\u7ba1\u7ebf\u7684\u63a8\u8fdb\u800c\u5bfc\u81f4\u3002<\/li>\n<li>2023 \u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684\u9500\u552e\u3001\u4e00\u822c\u53ca\u884c\u653f\u5f00\u652f\u4e3a 6,790 \u4e07\u7f8e\u5143\uff0c2022 \u5e74\u540c\u671f\u4e3a 6,340 \u4e07\u7f8e\u5143\u3002\u8fd9\u4e00\u589e\u957f\u4e3b\u8981\u662f\u7531\u4e8e\u4e3a\u652f\u6301\u65b0\u4ea7\u54c1\u4e0a\u5e02\u800c\u5bfc\u81f4\u7684\u4e00\u822c\u9500\u552e\u8d39\u7528\u7684\u589e\u52a0\u800c\u5bfc\u81f4\u3002<\/li>\n<li>2023 \u5e74\u7b2c\u4e8c\u5b63\u5ea6\u4e8f\u635f\u51c0\u989d\u4e3a 1.209 \u4ebf\u7f8e\u5143\uff0c\u6bcf\u80a1\u666e\u901a\u80a1\u4e8f\u635f\u4e3a 0.13 \u7f8e\u5143\uff0c2022 \u5e74\u540c\u671f\u4e8f\u635f\u51c0\u989d\u4e3a 1.379 \u4ebf\u7f8e\u5143\uff0c\u6bcf\u80a1\u666e\u901a\u80a1\u4e8f\u635f\u4e3a0.14 \u7f8e\u5143\u3002\u4e8f\u635f\u51c0\u989d\u51cf\u5c11\u4e3b\u8981\u662f\u7531\u4e8e\u4ea7\u54c1\u6536\u5165\u589e\u957f\u9ad8\u4e8e\u7ecf\u8425\u8d39\u7528\u7684\u589e\u957f\u800c\u5bfc\u81f4\u3002<\/li>\n<li>\u622a\u81f32023\u5e746\u670830\u65e5\uff0c\u73b0\u91d1\u53ca\u73b0\u91d1\u7b49\u4ef7\u7269\u3001\u77ed\u671f\u6295\u8d44\u548c\u53d7\u9650\u5236\u73b0\u91d1\u603b\u8ba1\u4e3a8.764\u4ebf\u7f8e\u5143\uff0c\u622a\u81f32023\u5e743\u670831\u65e5\u4e3a9.314\u4ebf\u7f8e\u5143\u3002<\/li>\n<\/ul>\n<p><b><u>\u7535\u8bdd\u4f1a\u8bae\u548c\u7f51\u7edc\u76f4\u64ad\u76f8\u5173\u4fe1\u606f<\/u><\/b><\/p>\n<p>\u518d\u9f0e\u533b\u836f\u5c06\u4e8e\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f42023\u5e748\u67088\u65e5\u4e0a\u53488\u70b9<i>\uff08\u5317\u4eac\u65f6\u95f4<\/i><i>8\u67088\u65e5\u665a20:00\uff09<\/i>\u4e3e\u529e\u7535\u8bdd\u4f1a\u8bae\u548c\u7f51\u7edc\u76f4\u64ad\u3002\u4e0e\u4f1a\u8005\u53ef\u4ee5\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9http:\/\/ir.zailaboratory.com\u53c2\u4e0e\u5b9e\u65f6\u7f51\u7edc\u76f4\u64ad\u3002\u5982\u8981\u53c2\u52a0\u7535\u8bdd\u4f1a\u8bae\uff0c\u9700\u63d0\u524d\u6ce8\u518c\u3002<\/p>\n<p>\u8be6\u7ec6\u4fe1\u606f\u5982\u4e0b\uff1a<\/p>\n<p>\u6ce8\u518c\u94fe\u63a5: <a href=\"https:\/\/register.vevent.com\/register\/BIb7d99f107c3347f29e117b2b7bc47034\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/register.vevent.com\/register\/BIb7d99f107c3347f29e117b2b7bc47034<\/a><\/p>\n<p>\u6240\u6709\u4e0e\u4f1a\u8005\u90fd\u5fc5\u987b\u5728\u7535\u8bdd\u4f1a\u8bae\u4e4b\u524d\u901a\u8fc7\u4e0a\u8ff0\u94fe\u63a5\u5b8c\u6210\u5728\u7ebf\u6ce8\u518c\u3002\u6ce8\u518c\u6210\u529f\u540e\uff0c\u60a8\u5c06\u6536\u5230\u786e\u8ba4\u90ae\u4ef6\uff0c\u5185\u542b\u62e8\u5165\u7535\u8bdd\u4f1a\u8bae\u7684\u5177\u4f53\u4fe1\u606f\u3002<\/p>\n<p>\u4f1a\u8bae\u7ed3\u675f\u540e\uff0c\u60a8\u53ef\u901a\u8fc7\u518d\u9f0e\u533b\u836f\u7f51\u7ad9\u89c2\u770b\u56de\u653e\u3002<\/p>\n<p><b>\u5173\u4e8e\u518d\u9f0e\u533b\u836f<\/b><\/p>\n<p>\u518d\u9f0e\u533b\u836f\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aZLAB\uff1b 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