{"id":89177,"date":"2023-02-20T22:32:00","date_gmt":"2023-02-20T15:32:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2023022022320089177"},"modified":"2023-02-21T02:57:19","modified_gmt":"2023-02-20T18:57:19","slug":"%e7%bd%97%e6%ac%a3%e8%8d%af%e4%b8%9a%e6%9b%bf%e6%88%88%e6%8b%89%e7%94%9f%e7%89%87%e6%96%b0%e9%80%82%e5%ba%94%e7%97%87%e5%8d%81%e4%ba%8c%e6%8c%87%e8%82%a0%e6%ba%83%e7%96%a1%e4%b8%8a%e5%b8%82%e7%94%b3","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2023022022320089177","title":{"rendered":"\u7f57\u6b23\u836f\u4e1a\u66ff\u6208\u62c9\u751f\u7247\u65b0\u9002\u5e94\u75c7\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u4e0a\u5e02\u7533\u8bf7\u83b7\u53d7\u7406"},"content":{"rendered":"

\u4e0a\u6d77<\/span>2023\u5e742\u670820\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u8fd1\u65e5\uff0c\u7f57\u6b23\u836f\u4e1a\u96c6\u56e2\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0"\u7f57\u6b23\u836f\u4e1a"\uff09\u6d88\u5316\u7cfb\u7edf\u75be\u75c5\u9886\u57df\u91cd\u70b9\u4ea7\u54c1\u3001\u56fd\u5bb6I\u7c7b\u521b\u65b0\u836f\u66ff\u6208\u62c9\u751f\u7247\uff08\u5546\u54c1\u540d\uff1a\u6cf0\u6b23\u8d5e<\/b>®<\/b>\uff09\u65b0\u9002\u5e94\u75c7\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97<\/b>\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\u3002<\/b>\u8fd9\u5c06\u6210\u4e3a\u7ee7\u53cd\u6d41\u6027\u98df\u7ba1\u708e\u540e\uff0c\u66ff\u6208\u62c9\u751f\u7247\u9012\u4ea4\u7684\u7b2c2\u4e2a\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n

\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u662f\u6211\u56fd\u4eba\u7fa4\u4e2d\u8f83\u4e3a\u5e38\u89c1\u3001\u591a\u53d1\u7684\u6162\u6027\u75c5\u4e4b\u4e00\uff0c\u662f\u6d88\u5316\u6027\u6e83\u75a1\u7684\u5e38\u89c1\u7c7b\u578b\uff0c\u7ea6\u5360\u6d88\u5316\u6027\u6e83\u75a1\u768470%\u3002\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u662f\u7531\u4e8e\u80c3\u6db2\u5206\u6ccc\u8fc7\u591a\u548c\uff08\u6216\uff09\u5341\u4e8c\u6307\u80a0\u9ecf\u819c\u9632\u5fa1\u529f\u80fd\u51cf\u5f31\uff0c\u5bfc\u81f4\u5341\u4e8c\u6307\u80a0\u9ecf\u819c\u88ab\u80c3\u6db2\u4e2d\u7684\u80c3\u9178\u6d88\u5316\u8150\u8680\uff0c\u5f62\u6210\u7684\u5c40\u90e8\u708e\u6027\u7834\u635f\uff0c\u5178\u578b\u8868\u73b0\u4e3a\u7a7a\u8179\u65f6\u4e2d\u4e0a\u8179\u75db\u3002\u60c5\u51b5\u4e25\u91cd\u65f6\uff0c\u8fd8\u4f1a\u635f\u4f24\u9ecf\u819c\u4e0b\u8840\u7ba1\u6216\u7a7f\u900f\u80a0\u58c1\u808c\u5c42\u800c\u5f15\u53d1\u51fa\u8840\u6216\u7a7f\u5b54\uff0c\u4e25\u91cd\u5371\u5bb3\u60a3\u8005\u7684\u5065\u5eb7\u548c\u751f\u547d\u3002<\/p>\n

\u66ff\u6208\u62c9\u751f\u7247\u662f\u4e2d\u56fd\u9996\u6b3e\u81ea\u7814\u94be\u79bb\u5b50\u7ade\u4e89\u6027\u9178\u963b\u6ede\u5242\uff08<\/b>P-CAB<\/b>\uff09\uff0c\u56fd\u5bb6<\/b>I<\/b>\u7c7b\u521b\u65b0\u836f\uff0c\u662f\u56fd\u5bb6"\u91cd\u5927\u65b0\u836f\u521b\u5236"\u79d1\u6280\u91cd\u5927\u4e13\u9879\u652f\u6301\u7814\u53d1\u7684\u9ad8\u79d1\u6280\u6210\u679c\u3002<\/b>\u66ff\u6208\u62c9\u751f\u7247\u62e5\u6709\u5168\u65b0\u7684\u6291\u9178\u4f5c\u7528\u673a\u5236\uff0c\u901a\u8fc7\u7ade\u4e89\u6027\u5730\u963b\u65adH+<\/sup>\/K+<\/sup>-ATP\u9176\u4e0a\u7684K+<\/sup>\u7ed3\u5408\u4f4d\u70b9\u800c\u8d77\u5230\u6291\u5236\u80c3\u9178\u5206\u6ccc\u7684\u4f5c\u7528\u3002\u548c\u4f20\u7edf\u6291\u9178\u836f\u7269\u76f8\u6bd4\uff0c\u66ff\u6208\u62c9\u751f\u7247\u62e5\u670930<\/b>\u5206\u949f\u5feb\u901f\u8d77\u6548\u3001\u9ecf\u819c\u6108\u5408\u7387\u9ad8\u3001\u6709\u6548\u6539\u5584\u591c\u95f4\u9178\u7a81\u7834\u3001\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u8f83\u5c11\uff0c\u4e14\u670d\u836f\u65b9\u4fbf\u4e0d\u53d7\u8fdb\u98df\u5f71\u54cd\u7b49\u663e\u8457\u4f18\u52bf\u3002\u66ff\u6208\u62c9\u751f\u7247\u6cbb\u7597\u53cd\u6d41\u6027\u98df\u7ba1\u708e\u5df2\u901a\u8fc7\u533b\u4fdd\u8c08\u5224\uff0c\u6210\u529f\u7eb3\u5165\u65b0\u7248\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\u3002<\/b>\u6b64\u5916\uff0c\u66ff\u6208\u62c9\u751f\u7247\u540e\u7eed\u9002\u5e94\u75c7\u4e5f\u5904\u4e8e\u7814\u53d1\u9636\u6bb5\uff0c\u8054\u5408\u9002\u5f53\u6297\u751f\u7d20\u6839\u9664\u5e7d\u95e8\u87ba\u6746\u83cc\uff08Hp\uff09\u9002\u5e94\u75c7\u6b63\u5728\u5f00\u5c55\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff1b\u66ff\u6208\u62c9\u751f\u6ce8\u5c04\u5242\u5df2\u542f\u52a8\u7814\u53d1\uff0c\u76ee\u524d\u5168\u7403\u8303\u56f4\u5185\u5c1a\u65e0\u540c\u7c7b\u6ce8\u5c04\u5242\u4ea7\u54c1\u4e0a\u5e02\u3002<\/p>\n

\n

\"\u66ff\u6208\u62c9\u751f\u7247\"<\/a>
\u66ff\u6208\u62c9\u751f\u7247<\/span><\/p>\n<\/p><\/div>\n

\u6b64\u6b21\u4e0a\u5e02\u7533\u8bf7\u662f\u57fa\u4e8e\u66ff\u6208\u62c9\u751f\u7247\u5728\u56fd\u5185\u5f00\u5c55\u7684\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u53cc\u6a21\u62df\u3001\u5e73\u884c\u5206\u7ec4\u3001\u6d3b\u6027\u5bf9\u7167\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u7531\u9996\u90fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5317\u4eac\u53cb\u8c0a\u533b\u9662\u5f20\u6f8d\u7530\u6559\u6388\u7275\u5934\uff0c\u65e8\u5728\u5bf9\u6bd4\u8bc4\u4ef7\u66ff\u6208\u62c9\u751f\u7247\u4e0e\u5170\u7d22\u62c9\u5511\u5728\u6cbb\u7597\u4e2d\u56fd\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u60a3\u8005\u4e2d\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u8bd5\u9a8c\u5171\u5165\u7ec4400\u4f8b\u60a3\u8005\uff0c\u7ecf\u8fc74\u5468\u62166\u5468\u7684\u6cbb\u7597\uff0c\u8bc1\u5b9e\u66ff\u6208\u62c9\u751f\u7247<\/b>50mg<\/b>\u6bcf\u65e5\u4e00\u6b21\u6cbb<\/b>\u7597<\/b>\u4e2d\u56fd\u5341\u4e8c\u6307<\/b>\u80a0\u6e83\u75a1<\/b>\u60a3\u8005<\/b>6<\/b>\u5468\u7d2f\u8ba1\u5185\u955c\u6e83\u75a1\u6108\u5408\u7387<\/b>\u975e\u52a3\u6548\u4e8e<\/b>\u5170<\/b>\u7d22\u62c9<\/b>\u5511<\/b>30mg<\/b>\uff0c<\/b>\u663e<\/b>\u8457<\/b>\u7f13<\/b>\u89e3\u60a3\u8005\u7684\u80c3<\/b>\u80a0<\/b>\u9053\u76f8\u5173\u75c7\u72b6\uff0c\u4e14\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u826f\u597d\u3002<\/b> <\/p>\n

\u8fd9\u9879III\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u4e3b\u8981\u7814\u7a76\u8005\u9996\u90fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5317\u4eac\u53cb\u8c0a\u533b\u9662\u5f20\u6f8d\u7530\u6559\u6388<\/b>\u8868\u793a\uff1a"\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u662f\u4e34\u5e8a\u5e38\u89c1\u7684\u6d88\u5316\u9053\u75be\u75c5\u4e4b\u4e00\uff0c\u6291\u9178\u6cbb\u7597\u662f\u7f13\u89e3\u5176\u75c7\u72b6\u3001\u6108\u5408\u6e83\u75a1\u7684\u4e3b\u8981\u63aa\u65bd\u3002\u901a\u8fc7\u8fd9\u9879III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u66ff\u6208\u62c9\u751f\u7247\u5728\u6cbb\u7597\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u65b9\u9762\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u5f97\u5230\u8bc1\u5b9e\uff0c\u8fd9\u5c06\u4e3a\u4e34\u5e8a\u533b\u751f\u548c\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u7528\u836f\u9009\u62e9\uff0c\u6539\u5584\u53ca\u63d0\u9ad8\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u3002"<\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

1.  \u6d88\u5316\u6027\u6e83\u75a1\u8bca\u65ad\u4e0e\u6cbb\u7597\u89c4\u8303\uff082016\u5e74\uff0c\u897f\u5b89\uff09[J].\u4e2d\u534e\u6d88\u5316\u6742\u5fd7,2016,36(8):508-513.<\/p>\n

2.  J Mermelstein, et al. Drugs Today (Barc). 2020 Nov;56(11):715-721.<\/p>\n

3.  He J, Cao G, Yu J, et al. Clin Drug Investig. 2021;41(1):89-97.<\/p>\n

4.  Sungpil Han<\/span>, et al. Clin Ther<\/span>. 2021 Aug;43(8):1371-1380.<\/p>\n

5.  Eunsol Yang\uff0cet al .Br J Clin Pharmacol . 2022 Feb 10.<\/p>\n

\u5173\u4e8e\u7f57\u6b23\u836f\u4e1a<\/u><\/b><\/p>\n

\u7f57\u6b23\u836f\u4e1a\u96c6\u56e2\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0"\u7f57\u6b23\u836f\u4e1a"\uff0c002793.SZ\uff09\u59cb\u521b\u4e8e1988\u5e74\uff0c\u79c9\u627f"\u4f20\u9012\u5065\u5eb7"\u7684\u4f01\u4e1a\u4f7f\u547d\uff0c\u4ee5\u79d1\u6280\u521b\u65b0\u4e3a\u5df1\u4efb\uff0c\u4e13\u6ce8\u4e8e\u6d88\u5316\u3001\u547c\u5438\u3001\u6297\u80bf\u7624\u7b49\u75be\u75c5\u9886\u57df\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u81f4\u529b\u4e8e\u4e3a\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u521b\u65b0\u836f\u7269\u9009\u62e9\u3002<\/p>\n

\u7f57\u6b23\u836f\u4e1a\u5df2\u4e0a\u5e02\u4e30\u5bcc\u4e14\u6709\u7ade\u4e89\u529b\u7684\u4ea7\u54c1\u7ec4\u5408\uff0c\u6838\u5fc3\u4ea7\u54c1\u5904\u4e8e\u6d88\u5316\u3001\u547c\u5438\u75be\u75c5\u7528\u836f\u5e02\u573a\u9886\u5148\u5730\u4f4d\u3002\u516c\u53f8\u591a\u4e2a\u4ea7\u54c1\u88ab\u5217\u5165"\u56fd\u5bb6\u91cd\u70b9\u65b0\u4ea7\u54c1\u8ba1\u5212"\u3001"\u56fd\u5bb6\u706b\u70ac\u8ba1\u5212"\u3001"\u91cd\u5927\u65b0\u836f\u521b\u5236"\u7b49\u79d1\u6280\u91cd\u5927\u4e13\u9879\u3002\u516c\u53f8\u81ea2006\u5e74\u5f00\u59cb\u8fde\u7eed\u8fdb\u5165\u4e2d\u56fd\u5236\u836f\u5de5\u4e1a\u767e\u5f3a\u4f01\u4e1a\uff0c\u81ea2011\u5e74\u4ee5\u6765\u8fde\u7eed\u88ab\u8bc4\u4e3a\u4e2d\u56fd\u533b\u836f\u7814\u53d1\u4ea7\u54c1\u7ebf\u6700\u4f73\u5de5\u4e1a\u4f01\u4e1a\uff0c\u662f\u56fd\u5bb6\u91cd\u70b9\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u3001\u56fd\u5bb6\u6280\u672f\u521b\u65b0\u793a\u8303\u4f01\u4e1a\u3001\u5168\u56fd\u5de5\u4e1a\u8d28\u91cf\u6807\u6746\u4f01\u4e1a\uff0c\u591a\u9879\u4ea7\u54c1\u79d1\u7814\u6210\u679c\u83b7\u5f97\u56fd\u5bb6\u79d1\u5b66\u6280\u672f\u8fdb\u6b65\u4e8c\u7b49\u5956\u3002<\/p>\n

\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95eewww.luoxin.cn<\/p>\n

 <\/p>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

\u4e0a\u6d772023\u5e742\u670820\u65e5 \/\u7f8e\u901a\u793e\/ — \u8fd1\u65e5\uff0c\u7f57\u6b23\u836f\u4e1a\u96c6\u56e2\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0"\u7f57\u6b23\u836f\u4e1a"\uff09\u6d88\u5316\u7cfb\u7edf\u75be\u75c5\u9886\u57df\u91cd\u70b9\u4ea7\u54c1\u3001\u56fd\u5bb6I\u7c7b\u521b\u65b0\u836f\u66ff\u6208\u62c9\u751f\u7247\uff08\u5546\u54c1\u540d\uff1a\u6cf0\u6b23\u8d5e®\uff09\u65b0\u9002\u5e94\u75c7\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\u3002\u8fd9\u5c06\u6210\u4e3a\u7ee7\u53cd\u6d41\u6027\u98df\u7ba1\u708e\u540e\uff0c\u66ff\u6208\u62c9\u751f\u7247\u9012\u4ea4\u7684\u7b2c2\u4e2a\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u7533\u8bf7\u3002 \u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u662f\u6211\u56fd\u4eba\u7fa4\u4e2d\u8f83\u4e3a\u5e38\u89c1\u3001\u591a\u53d1\u7684\u6162\u6027\u75c5\u4e4b\u4e00\uff0c\u662f\u6d88\u5316\u6027\u6e83\u75a1\u7684\u5e38\u89c1\u7c7b\u578b\uff0c\u7ea6\u5360\u6d88\u5316\u6027\u6e83\u75a1\u768470%\u3002\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u662f\u7531\u4e8e\u80c3\u6db2\u5206\u6ccc\u8fc7\u591a\u548c\uff08\u6216\uff09\u5341\u4e8c\u6307\u80a0\u9ecf\u819c\u9632\u5fa1\u529f\u80fd\u51cf\u5f31\uff0c\u5bfc\u81f4\u5341\u4e8c\u6307\u80a0\u9ecf\u819c\u88ab\u80c3\u6db2\u4e2d\u7684\u80c3\u9178\u6d88\u5316\u8150\u8680\uff0c\u5f62\u6210\u7684\u5c40\u90e8\u708e\u6027\u7834\u635f\uff0c\u5178\u578b\u8868\u73b0\u4e3a\u7a7a\u8179\u65f6\u4e2d\u4e0a\u8179\u75db\u3002\u60c5\u51b5\u4e25\u91cd\u65f6\uff0c\u8fd8\u4f1a\u635f\u4f24\u9ecf\u819c\u4e0b\u8840\u7ba1\u6216\u7a7f\u900f\u80a0\u58c1\u808c\u5c42\u800c\u5f15\u53d1\u51fa\u8840\u6216\u7a7f\u5b54\uff0c\u4e25\u91cd\u5371\u5bb3\u60a3\u8005\u7684\u5065\u5eb7\u548c\u751f\u547d\u3002 \u66ff\u6208\u62c9\u751f\u7247\u662f\u4e2d\u56fd\u9996\u6b3e\u81ea\u7814\u94be\u79bb\u5b50\u7ade\u4e89\u6027\u9178\u963b\u6ede\u5242\uff08P-CAB\uff09\uff0c\u56fd\u5bb6I\u7c7b\u521b\u65b0\u836f\uff0c\u662f\u56fd\u5bb6"\u91cd\u5927\u65b0\u836f\u521b\u5236"\u79d1\u6280\u91cd\u5927\u4e13\u9879\u652f\u6301\u7814\u53d1\u7684\u9ad8\u79d1\u6280\u6210\u679c\u3002\u66ff\u6208\u62c9\u751f\u7247\u62e5\u6709\u5168\u65b0\u7684\u6291\u9178\u4f5c\u7528\u673a\u5236\uff0c\u901a\u8fc7\u7ade\u4e89\u6027\u5730\u963b\u65adH+\/K+-ATP\u9176\u4e0a\u7684K+\u7ed3\u5408\u4f4d\u70b9\u800c\u8d77\u5230\u6291\u5236\u80c3\u9178\u5206\u6ccc\u7684\u4f5c\u7528\u3002\u548c\u4f20\u7edf\u6291\u9178\u836f\u7269\u76f8\u6bd4\uff0c\u66ff\u6208\u62c9\u751f\u7247\u62e5\u670930\u5206\u949f\u5feb\u901f\u8d77\u6548\u3001\u9ecf\u819c\u6108\u5408\u7387\u9ad8\u3001\u6709\u6548\u6539\u5584\u591c\u95f4\u9178\u7a81\u7834\u3001\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u8f83\u5c11\uff0c\u4e14\u670d\u836f\u65b9\u4fbf\u4e0d\u53d7\u8fdb\u98df\u5f71\u54cd\u7b49\u663e\u8457\u4f18\u52bf\u3002\u66ff\u6208\u62c9\u751f\u7247\u6cbb\u7597\u53cd\u6d41\u6027\u98df\u7ba1\u708e\u5df2\u901a\u8fc7\u533b\u4fdd\u8c08\u5224\uff0c\u6210\u529f\u7eb3\u5165\u65b0\u7248\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\u3002\u6b64\u5916\uff0c\u66ff\u6208\u62c9\u751f\u7247\u540e\u7eed\u9002\u5e94\u75c7\u4e5f\u5904\u4e8e\u7814\u53d1\u9636\u6bb5\uff0c\u8054\u5408\u9002\u5f53\u6297\u751f\u7d20\u6839\u9664\u5e7d\u95e8\u87ba\u6746\u83cc\uff08Hp\uff09\u9002\u5e94\u75c7\u6b63\u5728\u5f00\u5c55\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff1b\u66ff\u6208\u62c9\u751f\u6ce8\u5c04\u5242\u5df2\u542f\u52a8\u7814\u53d1\uff0c\u76ee\u524d\u5168\u7403\u8303\u56f4\u5185\u5c1a\u65e0\u540c\u7c7b\u6ce8\u5c04\u5242\u4ea7\u54c1\u4e0a\u5e02\u3002 \u66ff\u6208\u62c9\u751f\u7247 \u6b64\u6b21\u4e0a\u5e02\u7533\u8bf7\u662f\u57fa\u4e8e\u66ff\u6208\u62c9\u751f\u7247\u5728\u56fd\u5185\u5f00\u5c55\u7684\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u53cc\u6a21\u62df\u3001\u5e73\u884c\u5206\u7ec4\u3001\u6d3b\u6027\u5bf9\u7167\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u7531\u9996\u90fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5317\u4eac\u53cb\u8c0a\u533b\u9662\u5f20\u6f8d\u7530\u6559\u6388\u7275\u5934\uff0c\u65e8\u5728\u5bf9\u6bd4\u8bc4\u4ef7\u66ff\u6208\u62c9\u751f\u7247\u4e0e\u5170\u7d22\u62c9\u5511\u5728\u6cbb\u7597\u4e2d\u56fd\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u60a3\u8005\u4e2d\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u8bd5\u9a8c\u5171\u5165\u7ec4400\u4f8b\u60a3\u8005\uff0c\u7ecf\u8fc74\u5468\u62166\u5468\u7684\u6cbb\u7597\uff0c\u8bc1\u5b9e\u66ff\u6208\u62c9\u751f\u724750mg\u6bcf\u65e5\u4e00\u6b21\u6cbb\u7597\u4e2d\u56fd\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u60a3\u80056\u5468\u7d2f\u8ba1\u5185\u955c\u6e83\u75a1\u6108\u5408\u7387\u975e\u52a3\u6548\u4e8e\u5170\u7d22\u62c9\u551130mg\uff0c\u663e\u8457\u7f13\u89e3\u60a3\u8005\u7684\u80c3\u80a0\u9053\u76f8\u5173\u75c7\u72b6\uff0c\u4e14\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u826f\u597d\u3002  \u8fd9\u9879III\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u4e3b\u8981\u7814\u7a76\u8005\u9996\u90fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5317\u4eac\u53cb\u8c0a\u533b\u9662\u5f20\u6f8d\u7530\u6559\u6388\u8868\u793a\uff1a"\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u662f\u4e34\u5e8a\u5e38\u89c1\u7684\u6d88\u5316\u9053\u75be\u75c5\u4e4b\u4e00\uff0c\u6291\u9178\u6cbb\u7597\u662f\u7f13\u89e3\u5176\u75c7\u72b6\u3001\u6108\u5408\u6e83\u75a1\u7684\u4e3b\u8981\u63aa\u65bd\u3002\u901a\u8fc7\u8fd9\u9879III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u66ff\u6208\u62c9\u751f\u7247\u5728\u6cbb\u7597\u5341\u4e8c\u6307\u80a0\u6e83\u75a1\u65b9\u9762\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u5f97\u5230\u8bc1\u5b9e\uff0c\u8fd9\u5c06\u4e3a\u4e34\u5e8a\u533b\u751f\u548c\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u7528\u836f\u9009\u62e9\uff0c\u6539\u5584\u53ca\u63d0\u9ad8\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u3002" \u53c2\u8003\u6587\u732e\uff1a 1.  \u6d88\u5316\u6027\u6e83\u75a1\u8bca\u65ad\u4e0e\u6cbb\u7597\u89c4\u8303\uff082016\u5e74\uff0c\u897f\u5b89\uff09[J].\u4e2d\u534e\u6d88\u5316\u6742\u5fd7,2016,36(8):508-513. 2.  J Mermelstein, et al. Drugs Today (Barc). 2020 Nov;56(11):715-721. 3.  He J, Cao G, Yu J, et al. Clin Drug Investig. 2021;41(1):89-97. 4.  Sungpil Han, et al. Clin Ther. 2021 Aug;43(8):1371-1380. 5.  Eunsol Yang\uff0cet al .Br J Clin Pharmacol . 2022 Feb 10.… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":89180,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-89177","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/89177","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=89177"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/89177\/revisions"}],"predecessor-version":[{"id":89179,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/89177\/revisions\/89179"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/89180"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=89177"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=89177"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=89177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}