{"id":87953,"date":"2022-12-15T07:00:00","date_gmt":"2022-12-15T00:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022121507000087953"},"modified":"2022-12-15T22:17:13","modified_gmt":"2022-12-15T14:17:13","slug":"%e4%ba%91%e9%a1%b6%e6%96%b0%e8%80%80%e5%ae%a3%e5%b8%83%e6%96%b0%e7%9a%84-mrna-%e7%8b%82%e7%8a%ac%e7%97%85%e7%96%ab%e8%8b%97%e9%a1%b9%e7%9b%ae%ef%bc%8c%e5%b7%b2%e6%88%90%e5%8a%9f%e8%be%be%e5%88%b0","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022121507000087953","title":{"rendered":"\u4e91\u9876\u65b0\u8000\u5ba3\u5e03\u65b0\u7684 mRNA \u72c2\u72ac\u75c5\u75ab\u82d7\u9879\u76ee\uff0c\u5df2\u6210\u529f\u8fbe\u5230\u5176\u4e34\u5e8a\u524d\u91cc\u7a0b\u7891"},"content":{"rendered":"<p class=\"prntac\"><i>\u72c2\u72ac\u75c5\u75ab\u82d7\u9879\u76ee\u5728\u514d\u75ab\u539f\u6027\u7b49\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u53d6\u5f97\u4e86\u79ef\u6781\u7ed3\u679c<\/i><i>, <\/i><i>\u51f8\u663e\u4e86\u4e91\u9876\u65b0\u8000\u5f3a\u5927\u7684\u81ea\u4e3b\u7814\u53d1\u80fd\u529b<\/i><\/p>\n<p class=\"prntac\"><i>\u8fd9\u662f\u901a\u8fc7<\/i><i>mRNA<\/i><i>\u6280\u672f\u5e73\u53f0\u7814\u53d1\u7684\u9996\u4e2a\u975e\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u663e\u793a\u8be5\u5e73\u53f0\u5177\u6709\u5f00\u53d1\u9488\u5bf9\u4f20\u67d3\u75c5\u7b49\u591a\u79cd\u75be\u75c5\u9002\u5e94\u75c7\u4ea7\u54c1\u7684\u6f5c\u529b<\/i><\/p>\n<p class=\"prntac\"><i>\u516c\u53f8\u5df2\u901a\u8fc7<\/i><i>mRNA<\/i><i>\u6280\u672f\u5e73\u53f0\u7814\u53d1\u4e86\u4e16\u754c\u9886\u5148\u7684\u4e8c\u4ef7\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u8ba1\u5212\u4e8e\u660e\u5e74\u542f\u52a8\u4e34\u5e8a\u8bd5\u9a8c<\/i><\/p>\n<p><p><span class=\"legendSpanClass\">\u4e0a\u6d77<\/span><span class=\"legendSpanClass\">2022\u5e7412\u670815\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; <a href=\"https:\/\/www.everestmedicines.com\/\" target=\"_blank\" rel=\"nofollow noopener\">\u4e91\u9876\u65b0\u8000<\/a>\uff08HKEX 1952.HK\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u5927\u4e2d\u534e\u5730\u533a\u548c\u5176\u4ed6\u4e9a\u6d32\u5730\u533a\u5c1a\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff0c\u4eca\u65e5\u5ba3\u5e03\u5176\u65b0\u7814\u53d1\u7684mRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u9879\u76ee\u5728\u514d\u75ab\u539f\u6027\u7b49\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u53d6\u5f97\u4e86\u79ef\u6781\u7ed3\u679c, \u5df2\u8fbe\u5230\u5176\u4e34\u5e8a\u524d\u6982\u5ff5\u9a8c\u8bc1\u7684\u91cc\u7a0b\u7891 \uff08preclinical proof-of-concept milestone\uff09\u3002<span id=\"spanHghltb398\">\u8be5\u65b0\u578b\u5019\u9009\u75ab\u82d7\u662f\u516c\u53f8\u4e0e\u5408\u4f5c\u4f19\u4f34Providence Therapeutics Holdings Inc. \u5e94\u7528\u7ecf\u4e34\u5e8a\u9a8c\u8bc1\u7684mRNA\u6280\u672f\u5e73\u53f0\u7814\u53d1\uff0c<\/span>\u53ef\u7528\u4e8e\u72c2\u72ac\u75c5\u6bd2\u66b4\u9732\u540e\u7684\u9884\u9632\u6cbb\u7597\uff0c\u51f8\u663e\u4e86\u4e91\u9876\u65b0\u8000\u5f3a\u5927\u7684\u81ea\u4e3b\u7814\u53d1\u80fd\u529b\u3002<\/p>\n<p>\u4e91\u9876\u65b0\u8000\u9996\u5e2d\u6267\u884c\u5b98\u7f57\u6c38\u5e86\u8868\u793a\uff1a\u201cmRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u9879\u76ee\u662f\u6211\u4eec\u901a\u8fc7\u8be5mRNA\u6280\u672f\u5e73\u53f0\u7814\u53d1\u7684\u7b2c\u4e00\u4e2a\u975e\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u5145\u5206\u8bc1\u660e\u4e86\u6211\u4eec\u7684\u5185\u90e8\u7814\u53d1\u80fd\u529b\uff0c\u4e5f\u8bc1\u5b9e\u4e86\u8be5\u6280\u672f\u5e73\u53f0\u7684\u5f00\u53d1\u524d\u666f\u3002\u6211\u4eec\u7684\u4e00\u4ef7\u5019\u9009\u75ab\u82d7PTX-COVID19-B\u5728\u4e0e\u8f89\u745e\/BioNTech\u7684Comirnaty<sup>&reg; <\/sup>\u75ab\u82d7\u5934\u5bf9\u5934\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u5728\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u6bd4\u5bf9\u4e0a\u8fbe\u5230\u7edf\u8ba1\u5b66\u975e\u52a3\u6548\u3002\u6211\u4eec\u8fd8\u8fdb\u4e00\u6b65\u5e94\u7528mRNA\u5e73\u53f0\u7814\u53d1\u51fa\u4e86\u4e16\u754c\u9886\u5148\u7684\u9488\u5bf9\u5965\u5bc6\u514b\u620e\u7684\u4e8c\u4ef7\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u8ba1\u5212\u4e8e\u660e\u5e74\u542f\u52a8\u4e34\u5e8a\u8bd5\u9a8c\u3002\u516c\u53f8\u5c06\u7ee7\u7eed\u5229\u7528\u8fd9\u4e00\u91cd\u8981\u4e14\u5148\u8fdb\u7684\u6280\u672f\u5e73\u53f0\u7814\u53d1\u51fa\u9488\u5bf9\u4f20\u67d3\u75c5\u548c\u5176\u4ed6\u591a\u79cd\u75be\u75c5\u9002\u5e94\u75c7\u7684\u65b0\u578b\u9884\u9632\u53ca\u6cbb\u7597\u6027\u75ab\u82d7\u4ea7\u54c1\u3002\u201d<\/p>\n<p>\u5728\u4e0e\u5df2\u4e0a\u5e02\u7684\u706d\u6d3b\u72c2\u72ac\u75ab\u82d7\u7684\u5934\u5bf9\u5934\u514d\u75ab\u539f\u6027\u6bd4\u8f83\u8bd5\u9a8c\u4e2d\uff0c\u63a5\u79cd\u4e86\u4e24\u9488mRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u7684\u5c0f\u9f20\u5feb\u901f\u4ea7\u751f\u66f4\u52a0\u9ad8\u6548\u4ef7\u7684\u8840\u6e05\u4e2d\u548c\u6297\u4f53\uff0c\u5176\u6ef4\u5ea6\u663e\u8457\u9ad8\u4e8e\u6ce8\u5c04\u4e86\u56db\u9488\u706d\u6d3b\u72c2\u72ac\u75ab\u82d7\u514d\u75ab\u7684\u5c0f\u9f20\u8840\u6e05\u3002mRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u4e5f\u8bf1\u5bfc\u4e86\u663e\u8457\u9ad8\u4e8e\u706d\u6d3b\u72c2\u72ac\u75ab\u82d7\u7684T\u7ec6\u80de\u514d\u75ab\u5e94\u7b54&nbsp;(Th1\u504f\u5411)\u3002\u8be5\u75ab\u82d7\u4f18\u5316\u4e86\u514d\u75ab\u7a0b\u5e8f\uff0c\u4e3a\u5176\u4e34\u5e8a\u5f00\u53d1\u5960\u5b9a\u4e86\u57fa\u7840\u3002<\/p>\n<p>\u4e91\u9876\u65b0\u8000\u4e0e\u5408\u4f5c\u4f19\u4f34Providence\u62e5\u670950\/50\u5168\u7403\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u8be5\u65b0\u578bmRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u7684\u6743\u76ca\u3002<\/p>\n<p><b>\u5173\u4e8e\u72c2\u72ac\u75c5<\/b><\/p>\n<p>\u72c2\u72ac\u75c5\u662f\u4e00\u79cd\u4eba\u755c\u5171\u60a3\u7684\u75c5\u6bd2\u6027\u75be\u75c5\u3002\u867d\u7136\u76ee\u524d\u72c2\u72ac\u75c5\u5bf9\u4e8e\u516c\u5171\u536b\u751f\u800c\u8a00\u4ecd\u662f\u4e00\u4e2a\u4e25\u91cd\u5a01\u80c1\uff0c\u4f46\u8be5\u75be\u75c5\u53ef\u901a\u8fc7\u9002\u5f53\u7684\u75ab\u82d7\u63a5\u79cd\u8fdb\u884c\u9884\u9632\u3002\u5168\u7403\u6bcf\u5e74\u6709\u8d85\u8fc72900\u4e07\u4eba\u5728\u88ab\u52a8\u7269\u54ac\u4f24\u540e\u63a5\u79cd\u72c2\u72ac\u75c5\u75ab\u82d7<sup>[1]<\/sup>\u3002\u66b4\u9732\u4e8e\u72c2\u72ac\u75c5\u6bd2\u540e\u5c3d\u5feb\u63a5\u79cd\u75ab\u82d7\u53ef\u6709\u6548\u9884\u9632\u75c7\u72b6\u53d1\u4f5c\u3002\u7136\u800c\uff0c\u4e00\u65e6\u51fa\u73b0\u4e34\u5e8a\u75c7\u72b6\uff0c\u8fd9\u79cd\u75be\u75c5\u7684\u81f4\u6b7b\u7387\u51e0\u4e4e\u4e3a100%\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c&nbsp;95%\u4ee5\u4e0a\u7684\u72c2\u72ac\u75c5\u6b7b\u4ea1\u75c5\u4f8b\u53d1\u751f\u5728\u4e9a\u6d32\u548c\u975e\u6d32\u5730\u533a\uff0c\u4e3b\u8981\u5f71\u54cd\u751f\u6d3b\u5728\u504f\u8fdc\u519c\u6751\u5730\u533a\u7684\u5f31\u52bf\u4eba\u7fa4\u3002\u66b4\u9732\u540e\u9884\u9632\uff08PEP\uff09\u662f\u6307\u5728\u66b4\u9732\u4e8e\u72c2\u72ac\u75c5\u6bd2\u540e\u7acb\u5373\u5bf9\u88ab\u54ac\u4f24\u8005\u8fdb\u884c\u6cbb\u7597\uff0c\u5305\u62ec\u63a5\u79cd\u4e00\u4e2a\u7597\u7a0b\u7684\u6709\u6548\u72c2\u72ac\u75c5\u75ab\u82d7\uff0c\u4ee5\u53ca\u7acb\u5373\u6e05\u6d17\u4f24\u53e3\u5e76\u6ce8\u5c04\u72c2\u72ac\u75c5\u514d\u75ab\u7403\u86cb\u767d<sup>[2]<\/sup>\u3002<\/p>\n<p><b>\u5173\u4e8e\u4e91\u9876\u65b0\u8000<\/b><\/p>\n<p>\u4e91\u9876\u65b0\u8000\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u4e9a\u6d32\u5e02\u573a\u5c1a\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u4e91\u9876\u65b0\u8000\u7684\u7ba1\u7406\u56e2\u961f\u5728\u4e2d\u56fd\u53ca\u5168\u7403\u9886\u5148\u5236\u836f\u4f01\u4e1a\u4ece\u4e8b\u8fc7\u9ad8\u8d28\u91cf\u4e34\u5e8a\u5f00\u53d1\u3001\u836f\u653f\u4e8b\u52a1\u3001\u5316\u5b66\u5236\u9020\u4e0e\u63a7\u5236\uff08CMC\uff09\u3001\u4e1a\u52a1\u53d1\u5c55\u548c\u8fd0\u8425\uff0c\u62e5\u6709\u6df1\u539a\u7684\u4e13\u957f\u548c\u4e30\u5bcc\u7684\u7ecf\u9a8c\u3002\u4e91\u9876\u65b0\u8000\u5df2\u6253\u9020\u591a\u6b3e\u6709\u6f5c\u529b\u6210\u4e3a\u5168\u7403\u540c\u7c7b\u9996\u521b\u6216\u8005\u540c\u7c7b\u6700\u4f73\u7684\u836f\u7269\u7ec4\u5408\uff0c\u5176\u4e2d\u5927\u90e8\u5206\u5df2\u7ecf\u5904\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u540e\u671f\u9636\u6bb5\u3002\u516c\u53f8\u7684\u6cbb\u7597\u9886\u57df\u5305\u62ec\u5fc3\u80be\u75be\u75c5\u3001\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u548c\u4f20\u67d3\u6027\u75be\u75c5\u3002\u6709\u5173\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a&nbsp;<a href=\"http:\/\/www.everestmedicines.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.everestmedicines.com<\/a>\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e\uff1a<\/b><\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u4f1a\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\uff0c\u4e43\u57fa\u4e8e\u672c\u516c\u53f8\u6216\u7ba1\u7406\u5c42\u5728\u505a\u51fa\u8868\u8ff0\u65f6\u5bf9\u516c\u53f8\u4e1a\u52a1\u8fd0\u8425\u60c5\u51b5\u53ca\u8d22\u52a1\u72b6\u51b5\u7684\u73b0\u6709\u770b\u6cd5\u3001\u76f8\u4fe1\u3001\u548c\u73b0\u6709\u9884\u671f\uff0c\u53ef\u80fd\u4f1a\u4f7f\u7528\u201c\u5c06\u201d\u3001\u201c\u9884\u671f\u201d\u3001\u201c\u9884\u6d4b\u201d\u3001\u201c\u671f\u671b\u201d\u3001\u201c\u6253\u7b97\u201d\u3001\u201c\u8ba1\u5212\u201d\u3001\u201c\u76f8\u4fe1\u201d\u3001\u201c\u9884\u4f30\u201d\u3001\u201c\u786e\u4fe1\u201d\u53ca\u5176\u4ed6\u7c7b\u4f3c\u8bcd\u8bed\u8fdb\u884c\u8868\u8ff0\u3002\u8fd9\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u5e76\u975e\u5bf9\u672a\u6765\u4e1a\u7ee9\u7684\u4fdd\u8bc1\uff0c\u4f1a\u53d7\u5230\u98ce\u9669\u3001\u4e0d\u786e\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u8303\u56f4\uff0c\u96be\u4ee5\u9884\u8ba1\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u4eec\u7684\u4e1a\u52a1\u3001\u7ade\u4e89\u73af\u5883\u3001\u653f\u6cbb\u3001\u7ecf\u6d4e\u3001\u6cd5\u5f8b\u548c\u793e\u4f1a\u60c5\u51b5\u7684\u672a\u6765\u53d8\u5316\u53ca\u53d1\u5c55\u7b49\u5404\u79cd\u56e0\u7d20\u53ca\u5047\u8bbe\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4f1a\u4e0e\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8d44\u6599\u6709\u8f83\u5927\u5dee\u522b\u3002\u672c\u516c\u53f8\u53ca\u5404\u9644\u5c5e\u516c\u53f8\u3001\u5404\u4f4d\u8463\u4e8b\u3001\u7ba1\u7406\u4eba\u5458\u3001\u987e\u95ee\u53ca\u4ee3\u7406\u672a\u66fe\u4e14\u6982\u4e0d\u627f\u62c5\u66f4\u65b0\u8be5\u7a3f\u4ef6\u6240\u8f7d\u524d\u77bb\u6027\u8868\u8ff0\u4ee5\u53cd\u6620\u5728\u672c\u65b0\u95fb\u7a3f\u53d1\u5e03\u65e5\u540e\u6700\u65b0\u4fe1\u606f\u3001\u672a\u6765\u9879\u76ee\u6216\u60c5\u5f62\u7684\u4efb\u4f55\u4e49\u52a1\uff0c\u9664\u975e\u6cd5\u5f8b\u8981\u6c42\u3002<\/p>\n<p><sup>[1],[2] World Health Organization. (<span class=\"xn-chron\">November 2022<\/span>). <i>Rabies.<\/i> World Health Organization. Retrieved from <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/rabies\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/rabies<\/a><\/sup><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u72c2\u72ac\u75c5\u75ab\u82d7\u9879\u76ee\u5728\u514d\u75ab\u539f\u6027\u7b49\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u53d6\u5f97\u4e86\u79ef\u6781\u7ed3\u679c, \u51f8\u663e\u4e86\u4e91\u9876\u65b0\u8000\u5f3a\u5927\u7684\u81ea\u4e3b\u7814\u53d1\u80fd\u529b \u8fd9\u662f\u901a\u8fc7mRNA\u6280\u672f\u5e73\u53f0\u7814\u53d1\u7684\u9996\u4e2a\u975e\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u663e\u793a\u8be5\u5e73\u53f0\u5177\u6709\u5f00\u53d1\u9488\u5bf9\u4f20\u67d3\u75c5\u7b49\u591a\u79cd\u75be\u75c5\u9002\u5e94\u75c7\u4ea7\u54c1\u7684\u6f5c\u529b \u516c\u53f8\u5df2\u901a\u8fc7mRNA\u6280\u672f\u5e73\u53f0\u7814\u53d1\u4e86\u4e16\u754c\u9886\u5148\u7684\u4e8c\u4ef7\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u8ba1\u5212\u4e8e\u660e\u5e74\u542f\u52a8\u4e34\u5e8a\u8bd5\u9a8c \u4e0a\u6d772022\u5e7412\u670815\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u4e91\u9876\u65b0\u8000\uff08HKEX 1952.HK\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u5927\u4e2d\u534e\u5730\u533a\u548c\u5176\u4ed6\u4e9a\u6d32\u5730\u533a\u5c1a\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff0c\u4eca\u65e5\u5ba3\u5e03\u5176\u65b0\u7814\u53d1\u7684mRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u9879\u76ee\u5728\u514d\u75ab\u539f\u6027\u7b49\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u53d6\u5f97\u4e86\u79ef\u6781\u7ed3\u679c, \u5df2\u8fbe\u5230\u5176\u4e34\u5e8a\u524d\u6982\u5ff5\u9a8c\u8bc1\u7684\u91cc\u7a0b\u7891 \uff08preclinical proof-of-concept milestone\uff09\u3002\u8be5\u65b0\u578b\u5019\u9009\u75ab\u82d7\u662f\u516c\u53f8\u4e0e\u5408\u4f5c\u4f19\u4f34Providence Therapeutics Holdings Inc. \u5e94\u7528\u7ecf\u4e34\u5e8a\u9a8c\u8bc1\u7684mRNA\u6280\u672f\u5e73\u53f0\u7814\u53d1\uff0c\u53ef\u7528\u4e8e\u72c2\u72ac\u75c5\u6bd2\u66b4\u9732\u540e\u7684\u9884\u9632\u6cbb\u7597\uff0c\u51f8\u663e\u4e86\u4e91\u9876\u65b0\u8000\u5f3a\u5927\u7684\u81ea\u4e3b\u7814\u53d1\u80fd\u529b\u3002 \u4e91\u9876\u65b0\u8000\u9996\u5e2d\u6267\u884c\u5b98\u7f57\u6c38\u5e86\u8868\u793a\uff1a\u201cmRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u9879\u76ee\u662f\u6211\u4eec\u901a\u8fc7\u8be5mRNA\u6280\u672f\u5e73\u53f0\u7814\u53d1\u7684\u7b2c\u4e00\u4e2a\u975e\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u5145\u5206\u8bc1\u660e\u4e86\u6211\u4eec\u7684\u5185\u90e8\u7814\u53d1\u80fd\u529b\uff0c\u4e5f\u8bc1\u5b9e\u4e86\u8be5\u6280\u672f\u5e73\u53f0\u7684\u5f00\u53d1\u524d\u666f\u3002\u6211\u4eec\u7684\u4e00\u4ef7\u5019\u9009\u75ab\u82d7PTX-COVID19-B\u5728\u4e0e\u8f89\u745e\/BioNTech\u7684Comirnaty&reg; \u75ab\u82d7\u5934\u5bf9\u5934\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u5728\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u6bd4\u5bf9\u4e0a\u8fbe\u5230\u7edf\u8ba1\u5b66\u975e\u52a3\u6548\u3002\u6211\u4eec\u8fd8\u8fdb\u4e00\u6b65\u5e94\u7528mRNA\u5e73\u53f0\u7814\u53d1\u51fa\u4e86\u4e16\u754c\u9886\u5148\u7684\u9488\u5bf9\u5965\u5bc6\u514b\u620e\u7684\u4e8c\u4ef7\u65b0\u51a0\u5019\u9009\u75ab\u82d7\uff0c\u8ba1\u5212\u4e8e\u660e\u5e74\u542f\u52a8\u4e34\u5e8a\u8bd5\u9a8c\u3002\u516c\u53f8\u5c06\u7ee7\u7eed\u5229\u7528\u8fd9\u4e00\u91cd\u8981\u4e14\u5148\u8fdb\u7684\u6280\u672f\u5e73\u53f0\u7814\u53d1\u51fa\u9488\u5bf9\u4f20\u67d3\u75c5\u548c\u5176\u4ed6\u591a\u79cd\u75be\u75c5\u9002\u5e94\u75c7\u7684\u65b0\u578b\u9884\u9632\u53ca\u6cbb\u7597\u6027\u75ab\u82d7\u4ea7\u54c1\u3002\u201d \u5728\u4e0e\u5df2\u4e0a\u5e02\u7684\u706d\u6d3b\u72c2\u72ac\u75ab\u82d7\u7684\u5934\u5bf9\u5934\u514d\u75ab\u539f\u6027\u6bd4\u8f83\u8bd5\u9a8c\u4e2d\uff0c\u63a5\u79cd\u4e86\u4e24\u9488mRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u7684\u5c0f\u9f20\u5feb\u901f\u4ea7\u751f\u66f4\u52a0\u9ad8\u6548\u4ef7\u7684\u8840\u6e05\u4e2d\u548c\u6297\u4f53\uff0c\u5176\u6ef4\u5ea6\u663e\u8457\u9ad8\u4e8e\u6ce8\u5c04\u4e86\u56db\u9488\u706d\u6d3b\u72c2\u72ac\u75ab\u82d7\u514d\u75ab\u7684\u5c0f\u9f20\u8840\u6e05\u3002mRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u4e5f\u8bf1\u5bfc\u4e86\u663e\u8457\u9ad8\u4e8e\u706d\u6d3b\u72c2\u72ac\u75ab\u82d7\u7684T\u7ec6\u80de\u514d\u75ab\u5e94\u7b54&nbsp;(Th1\u504f\u5411)\u3002\u8be5\u75ab\u82d7\u4f18\u5316\u4e86\u514d\u75ab\u7a0b\u5e8f\uff0c\u4e3a\u5176\u4e34\u5e8a\u5f00\u53d1\u5960\u5b9a\u4e86\u57fa\u7840\u3002 \u4e91\u9876\u65b0\u8000\u4e0e\u5408\u4f5c\u4f19\u4f34Providence\u62e5\u670950\/50\u5168\u7403\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u8be5\u65b0\u578bmRNA\u72c2\u72ac\u75c5\u75ab\u82d7\u7684\u6743\u76ca\u3002 \u5173\u4e8e\u72c2\u72ac\u75c5 \u72c2\u72ac\u75c5\u662f\u4e00\u79cd\u4eba\u755c\u5171\u60a3\u7684\u75c5\u6bd2\u6027\u75be\u75c5\u3002\u867d\u7136\u76ee\u524d\u72c2\u72ac\u75c5\u5bf9\u4e8e\u516c\u5171\u536b\u751f\u800c\u8a00\u4ecd\u662f\u4e00\u4e2a\u4e25\u91cd\u5a01\u80c1\uff0c\u4f46\u8be5\u75be\u75c5\u53ef\u901a\u8fc7\u9002\u5f53\u7684\u75ab\u82d7\u63a5\u79cd\u8fdb\u884c\u9884\u9632\u3002\u5168\u7403\u6bcf\u5e74\u6709\u8d85\u8fc72900\u4e07\u4eba\u5728\u88ab\u52a8\u7269\u54ac\u4f24\u540e\u63a5\u79cd\u72c2\u72ac\u75c5\u75ab\u82d7[1]\u3002\u66b4\u9732\u4e8e\u72c2\u72ac\u75c5\u6bd2\u540e\u5c3d\u5feb\u63a5\u79cd\u75ab\u82d7\u53ef\u6709\u6548\u9884\u9632\u75c7\u72b6\u53d1\u4f5c\u3002\u7136\u800c\uff0c\u4e00\u65e6\u51fa\u73b0\u4e34\u5e8a\u75c7\u72b6\uff0c\u8fd9\u79cd\u75be\u75c5\u7684\u81f4\u6b7b\u7387\u51e0\u4e4e\u4e3a100%\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c&nbsp;95%\u4ee5\u4e0a\u7684\u72c2\u72ac\u75c5\u6b7b\u4ea1\u75c5\u4f8b\u53d1\u751f\u5728\u4e9a\u6d32\u548c\u975e\u6d32\u5730\u533a\uff0c\u4e3b\u8981\u5f71\u54cd\u751f\u6d3b\u5728\u504f\u8fdc\u519c\u6751\u5730\u533a\u7684\u5f31\u52bf\u4eba\u7fa4\u3002\u66b4\u9732\u540e\u9884\u9632\uff08PEP\uff09\u662f\u6307\u5728\u66b4\u9732\u4e8e\u72c2\u72ac\u75c5\u6bd2\u540e\u7acb\u5373\u5bf9\u88ab\u54ac\u4f24\u8005\u8fdb\u884c\u6cbb\u7597\uff0c\u5305\u62ec\u63a5\u79cd\u4e00\u4e2a\u7597\u7a0b\u7684\u6709\u6548\u72c2\u72ac\u75c5\u75ab\u82d7\uff0c\u4ee5\u53ca\u7acb\u5373\u6e05\u6d17\u4f24\u53e3\u5e76\u6ce8\u5c04\u72c2\u72ac\u75c5\u514d\u75ab\u7403\u86cb\u767d[2]\u3002 \u5173\u4e8e\u4e91\u9876\u65b0\u8000 \u4e91\u9876\u65b0\u8000\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u4e9a\u6d32\u5e02\u573a\u5c1a\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u4e91\u9876\u65b0\u8000\u7684\u7ba1\u7406\u56e2\u961f\u5728\u4e2d\u56fd\u53ca\u5168\u7403\u9886\u5148\u5236\u836f\u4f01\u4e1a\u4ece\u4e8b\u8fc7\u9ad8\u8d28\u91cf\u4e34\u5e8a\u5f00\u53d1\u3001\u836f\u653f\u4e8b\u52a1\u3001\u5316\u5b66\u5236\u9020\u4e0e\u63a7\u5236\uff08CMC\uff09\u3001\u4e1a\u52a1\u53d1\u5c55\u548c\u8fd0\u8425\uff0c\u62e5\u6709\u6df1\u539a\u7684\u4e13\u957f\u548c\u4e30\u5bcc\u7684\u7ecf\u9a8c\u3002\u4e91\u9876\u65b0\u8000\u5df2\u6253\u9020\u591a\u6b3e\u6709\u6f5c\u529b\u6210\u4e3a\u5168\u7403\u540c\u7c7b\u9996\u521b\u6216\u8005\u540c\u7c7b\u6700\u4f73\u7684\u836f\u7269\u7ec4\u5408\uff0c\u5176\u4e2d\u5927\u90e8\u5206\u5df2\u7ecf\u5904\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u540e\u671f\u9636\u6bb5\u3002\u516c\u53f8\u7684\u6cbb\u7597\u9886\u57df\u5305\u62ec\u5fc3\u80be\u75be\u75c5\u3001\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u548c\u4f20\u67d3\u6027\u75be\u75c5\u3002\u6709\u5173\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a&nbsp;www.everestmedicines.com\u3002 \u524d\u77bb\u6027\u58f0\u660e\uff1a \u672c\u65b0\u95fb\u7a3f\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u4f1a\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\uff0c\u4e43\u57fa\u4e8e\u672c\u516c\u53f8\u6216\u7ba1\u7406\u5c42\u5728\u505a\u51fa\u8868\u8ff0\u65f6\u5bf9\u516c\u53f8\u4e1a\u52a1\u8fd0\u8425\u60c5\u51b5\u53ca\u8d22\u52a1\u72b6\u51b5\u7684\u73b0\u6709\u770b\u6cd5\u3001\u76f8\u4fe1\u3001\u548c\u73b0\u6709\u9884\u671f\uff0c\u53ef\u80fd\u4f1a\u4f7f\u7528\u201c\u5c06\u201d\u3001\u201c\u9884\u671f\u201d\u3001\u201c\u9884\u6d4b\u201d\u3001\u201c\u671f\u671b\u201d\u3001\u201c\u6253\u7b97\u201d\u3001\u201c\u8ba1\u5212\u201d\u3001\u201c\u76f8\u4fe1\u201d\u3001\u201c\u9884\u4f30\u201d\u3001\u201c\u786e\u4fe1\u201d\u53ca\u5176\u4ed6\u7c7b\u4f3c\u8bcd\u8bed\u8fdb\u884c\u8868\u8ff0\u3002\u8fd9\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u5e76\u975e\u5bf9\u672a\u6765\u4e1a\u7ee9\u7684\u4fdd\u8bc1\uff0c\u4f1a\u53d7\u5230\u98ce\u9669\u3001\u4e0d\u786e\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u8303\u56f4\uff0c\u96be\u4ee5\u9884\u8ba1\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u4eec\u7684\u4e1a\u52a1\u3001\u7ade\u4e89\u73af\u5883\u3001\u653f\u6cbb\u3001\u7ecf\u6d4e\u3001\u6cd5\u5f8b\u548c\u793e\u4f1a\u60c5\u51b5\u7684\u672a\u6765\u53d8\u5316\u53ca\u53d1\u5c55\u7b49\u5404\u79cd\u56e0\u7d20\u53ca\u5047\u8bbe\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4f1a\u4e0e\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8d44\u6599\u6709\u8f83\u5927\u5dee\u522b\u3002\u672c\u516c\u53f8\u53ca\u5404\u9644\u5c5e\u516c\u53f8\u3001\u5404\u4f4d\u8463\u4e8b\u3001\u7ba1\u7406\u4eba\u5458\u3001\u987e\u95ee\u53ca\u4ee3\u7406\u672a\u66fe\u4e14\u6982\u4e0d\u627f\u62c5\u66f4\u65b0\u8be5\u7a3f\u4ef6\u6240\u8f7d\u524d\u77bb\u6027\u8868\u8ff0\u4ee5\u53cd\u6620\u5728\u672c\u65b0\u95fb\u7a3f\u53d1\u5e03\u65e5\u540e\u6700\u65b0\u4fe1\u606f\u3001\u672a\u6765\u9879\u76ee\u6216\u60c5\u5f62\u7684\u4efb\u4f55\u4e49\u52a1\uff0c\u9664\u975e\u6cd5\u5f8b\u8981\u6c42\u3002 [1],[2] World Health Organization. (November 2022). Rabies. World Health Organization. Retrieved from https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/rabies &nbsp;&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2022121507000087953\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-87953","post","type-post","status-publish","format-standard","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/87953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=87953"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/87953\/revisions"}],"predecessor-version":[{"id":87954,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/87953\/revisions\/87954"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=87953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=87953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=87953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}