{"id":85762,"date":"2022-11-21T20:00:00","date_gmt":"2022-11-21T13:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022112120000085762"},"modified":"2022-11-21T22:44:21","modified_gmt":"2022-11-21T14:44:21","slug":"%e9%a9%af%e9%b9%bf%e7%94%9f%e7%89%a9%e5%92%8cumoja-biopharma%e5%90%88%e4%bd%9c%e5%bc%80%e5%8f%91%e8%a1%80%e6%b6%b2%e7%b3%bb%e7%bb%9f%e6%81%b6%e6%80%a7%e8%82%bf%e7%98%a4%e5%8d%b3%e7%94%a8%e5%9e%8b","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022112120000085762","title":{"rendered":"\u9a6f\u9e7f\u751f\u7269\u548cUmoja Biopharma\u5408\u4f5c\u5f00\u53d1\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u5373\u7528\u578b\u7597\u6cd5"},"content":{"rendered":"

\u53cc\u65b9\u7684\u5408\u4f5c\u5c06\u7ed3\u5408\u9a6f\u9e7f\u751f\u7269\u7684\u5d4c\u5408\u6297\u539f\u53d7\u4f53\uff08<\/i>CARs<\/i>\uff09\u4e0e<\/i>Umoja<\/i>\u7684<\/i>iCIL<\/i>\u5e73\u53f0<\/span>\uff0c\u4ee5\u5f00\u53d1\u4e0b\u4e00\u4ee3\u5373\u7528\u578b\u7684\u7ec6\u80de\u7597\u6cd5\uff0c \u4ee5\u6cbb\u7597\u6807\u51c6\u7597\u6cd5\u4e0d\u80fd\u6ee1\u8db3\u7684\u9002\u5e94\u75c7\u3002<\/i><\/p>\n

\u5357\u4eac\u3001\u4e0a\u6d77\u548c\u7f8e\u56fd\u5723\u8377\u897f<\/span>2022\u5e7411\u670821\u65e5<\/span> \/\u7f8e\u901a\u793e\/ —  \u9a6f\u9e7f\u751f\u7269\uff08"IASO Bio"\uff09\uff0c\u4e00\u5bb6\u4ece\u4e8b\u53d1\u73b0\u3001\u5f00\u53d1\u548c\u5236\u9020\u521b\u65b0\u836f\u7269\u7684\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0cUmoja Biopharma, Inc. \u4e00\u5bb6\u4ee5\u5f00\u521b\u5373\u7528\u578b\u7efc\u5408\u7597\u6cd5\uff0c\u53ef\u91cd\u65b0\u7f16\u7a0b\u514d\u75ab\u7ec6\u80de\u4ee5\u6cbb\u7597\u5b9e\u4f53\u7624\u548c\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u7684\u514d\u75ab\u80bf\u7624\u5b66\u516c\u53f8\uff0c\u4eca\u5929\u5171\u540c\u5ba3\u5e03\u53cc\u65b9\u5df2\u8fbe\u6210\u4e00\u9879\u7814\u7a76\u534f\u8bae\uff0c\u4ee5\u8bc4\u4f30 Umoja \u7684 iCIL \u5e73\u53f0\u7ed3\u5408IASO \u7684\u4e1a\u754c\u6700\u4f18 CAR\uff0c\u5f00\u53d1\u5373\u7528\u578b\u7597\u6cd5\uff0c\u4e3a\u6025\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u53ca\u6f5c\u5728\u5176\u4ed6\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u60a3\u8005\uff0c\u63d0\u4f9b\u53ef\u8d1f\u62c5\u3001\u4fbf\u6377\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n

\n

\"\"<\/a>
<\/span><\/p>\n<\/p><\/div>\n

\u9a6f\u9e7f\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u6c6a\u6587\u535a\u58eb\u8868\u793a<\/b>\uff1a"\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0eUmoja\u8fbe\u6210\u5408\u4f5c\u3002\u6211\u4eec\u7684\u5168\u4eba\u6e90 CAR \u7ed3\u6784\u7684\u4f18\u52bf\u5728\u9488\u5bf9\u591a\u4e2a\u9776\u70b9\uff0c\u5e7f\u6cdb\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5df2\u7ecf\u5f97\u5230\u9a8c\u8bc1\u3002\u6211\u4eec\u5f88\u9ad8\u5174\u5c06\u6211\u4eec\u7684 CAR \u7ed3\u6784\u4e0e Umoja \u7684\u65b0\u578b ShRED \u6280\u672f\u76f8\u7ed3\u5408\uff0c\u4ee5\u66f4\u4f4e\u7684\u6210\u672c\u5f00\u53d1\u5373\u7528\u578b\u4e0b\u4e00\u4ee3\u65b0\u578b\u7ec6\u80de\u7597\u6cd5\u3002"<\/p>\n

\u9a6f\u9e7f\u751f\u7269\u5229\u7528\u5176\u4e13\u6709\u7684\u5168\u4eba\u6e90\u6297\u4f53\u53d1\u73b0\u5e73\u53f0\uff08IMARS\uff09\u3001\u9ad8\u901a\u91cf CAR \u7b5b\u9009\u5e73\u53f0\u3001\u5feb\u901f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6267\u884c\u529b\uff0c\u4ee5\u53ca\u81ea\u6709\u7684\u8d28\u7c92\u3001\u75c5\u6bd2\u8f7d\u4f53\u548c CAR-T \u7ec6\u80de\u751f\u4ea7\u6210\u529f\u7387\u5747\u8d85\u8fc790%\u7684GMP\u751f\u4ea7\u8bbe\u65bd\u6765\u7b5b\u9009\u6f5c\u5728\u4e1a\u754c\u6700\u4f18\u7684 CAR\u3002\u540c\u65f6\uff0c\u516c\u53f8\u4e5f\u81f4\u529b\u4e8e\u5c06\u5176\u521b\u65b0\u7597\u6cd5\u5e26\u7ed9\u5168\u7403\u66f4\u5e7f\u6cdb\u7684\u4eba\u7fa4\u3002<\/p>\n

"\u6211\u4eec\u76f8\u4fe1\uff0c\u7ed3\u5408\u6211\u4eec\u7684 iCIL \u5e73\u53f0\u548c\u9a6f\u9e7f\u751f\u7269\u7684 CAR \u5f00\u53d1\u7684\u5373\u7528\u578b\u7597\u6cd5\u5c06\u4e3a\u66f4\u5e7f\u6cdb\u7684\u60a3\u8005\u83b7\u5f97\u8840\u6db2\u6076\u6027\u80bf\u7624\u7684\u6700\u4f18\u7597\u6cd5\u94fa\u5e73\u9053\u8def\uff0c"Umoja<\/b>\u8054\u5408\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u6267\u884c\u5b98<\/b>,<\/b>\u533b\u5b66\u535a\u58eb<\/b> Andy Scharenberg<\/b>\u8bf4<\/b>,"\u968f\u7740\u533b\u5b66\u548c\u79d1\u5b66\u7684\u8fdb\u6b65\uff0c\u764c\u75c7\u60a3\u8005\u7684\u6cbb\u7597\u65b9\u6cd5\u4e5f\u5728\u8fdb\u6b65\uff0c\u4f46\u6211\u4eec\u8fd8\u6709\u5f88\u957f\u7684\u8def\u8981\u8d70\u3002 Umoja \u548c\u9a6f\u9e7f\u751f\u7269\u4e4b\u95f4\u7684\u5408\u4f5c\u65e8\u5728\u63a8\u52a8\u4e0b\u4e00\u9636\u6bb5\u7684\u764c\u75c7\u6cbb\u7597\u3002"<\/p>\n

Umoja \u57fa\u4e8e iPSC \u7684\u540c\u79cd\u5f02\u4f53\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0\u4f7f\u7528\u5176\u5408\u6210\u53d7\u4f53\u542f\u7528\u5206\u5316\uff08ShRED\uff09\u5236\u9020\u5de5\u827a\u6765\u6307\u5bfc iCILs \u7684\u5206\u5316\u548c\u6269\u589e\uff0ciCILs \u662f\u4e00\u79cd\u65b0\u578b\u7684\u5148\u5929\u6027\u6dcb\u5df4\u7ec6\u80de\uff0c\u5177\u6709\u5f3a\u5927\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002 ShRED \u751f\u6210\u7684 iCIL \u5728\u65e0\u9972\u517b\u5c42\u7ec6\u80de\u57f9\u517b100 \u5929\u540e\u4ecd\u4fdd\u7559\u529f\u80fd\uff0c\u5e76\u4e14\u7531\u4e8e ShRED \u4e0d\u9700\u8981\u9972\u517b\u5c42\u7ec6\u80de\u6765\u8bf1\u5bfc\u6548\u5e94\u7ec6\u80de\u6269\u589e\uff0c\u56e0\u6b64\u8fd9\u4e9b\u7ec6\u80de\u65e0\u9700\u591a\u79cd\u590d\u6742\u539f\u6750\u6599\u5373\u53ef\u4fdd\u6301\u5176\u589e\u6b96\u80fd\u529b\u3002<\/p>\n

\u5173\u4e8e<\/b>Umoja<\/b>\u7684<\/b>iCIL<\/b>™\u5e73\u53f0\uff1a\u8bf1\u5bfc\u7684\u7ec6\u80de\u6bd2\u6027\u5148\u5929\u6dcb\u5df4\u7ec6\u80de <\/b><\/p>\n

Umoja\u7684iCIL™\u5e73\u53f0\u662f\u4e00\u79cd\u5168\u65b0\u7684\u7ec6\u80de\u751f\u4ea7\u5de5\u827a\uff0c\u53ef\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u5927\u89c4\u6a21\u5206\u5316\u4e3a\u6297\u764c\u7ec6\u80de\u3002\u8fd9\u4e9b\u7ec6\u80de\uff0c\u79f0\u4e3a\u8bf1\u5bfc\u7ec6\u80de\u6bd2\u6027\u5148\u5929\u6dcb\u5df4\u7ec6\u80de\u6216iCIL\uff0c\u8f93\u6ce8\u5230\u60a3\u8005\u4f53\u5185\u540e\u53ef\u589e\u5f3a\u5176\u5185\u6e90\u6027\u6297\u80bf\u7624\u514d\u75ab\u529f\u80fd\uff0c\u5e76\u4e0eVivoVec\u4ea7\u751f\u7684\u4f53\u5185CAR-T\u7ec6\u80de\u4e00\u8d77\u4ea7\u751f\u534f\u540c\u4f5c\u7528\u3002\u4e0eVivoVec\u751f\u6210\u7684CAR-T\u7ec6\u80de\u7c7b\u4f3c\uff0ciCIL\u53ef\u4ee5\u5229\u7528\u6211\u4eec\u7684RACR\/CAR™\u548cTumorTag™\u5e73\u53f0\u8fdb\u884c\u57fa\u56e0\u7f16\u8f91\uff0c\u6765\u652f\u6301\u7ec6\u80de\u5b58\u6d3b\u5e76\u9776\u5411\u80bf\u7624\u53ca\u5176\u57fa\u8d28\u7ec6\u80de\uff0c\u4ece\u800c\u53ef\u80fd\u51cf\u5c11\u4e0d\u826f\u4e8b\u4ef6\u5e76\u5ef6\u957f\u60a3\u8005\u7684\u7f13\u89e3\u671f\u3002\u5173\u4e8eUmoja\u7684\u5e73\u53f0\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95eehttps:\/\/www.umoja-biopharma.com\/our-science\/<\/a>\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u53cc\u65b9\u7684\u5408\u4f5c\u5c06\u7ed3\u5408\u9a6f\u9e7f\u751f\u7269\u7684\u5d4c\u5408\u6297\u539f\u53d7\u4f53\uff08CARs\uff09\u4e0eUmoja\u7684iCIL\u5e73\u53f0\uff0c\u4ee5\u5f00\u53d1\u4e0b\u4e00\u4ee3\u5373\u7528\u578b\u7684\u7ec6\u80de\u7597\u6cd5\uff0c \u4ee5\u6cbb\u7597\u6807\u51c6\u7597\u6cd5\u4e0d\u80fd\u6ee1\u8db3\u7684\u9002\u5e94\u75c7\u3002 \u5357\u4eac\u3001\u4e0a\u6d77\u548c\u7f8e\u56fd\u5723\u8377\u897f2022\u5e7411\u670821\u65e5 \/\u7f8e\u901a\u793e\/ —  \u9a6f\u9e7f\u751f\u7269\uff08"IASO Bio"\uff09\uff0c\u4e00\u5bb6\u4ece\u4e8b\u53d1\u73b0\u3001\u5f00\u53d1\u548c\u5236\u9020\u521b\u65b0\u836f\u7269\u7684\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0cUmoja Biopharma, Inc. \u4e00\u5bb6\u4ee5\u5f00\u521b\u5373\u7528\u578b\u7efc\u5408\u7597\u6cd5\uff0c\u53ef\u91cd\u65b0\u7f16\u7a0b\u514d\u75ab\u7ec6\u80de\u4ee5\u6cbb\u7597\u5b9e\u4f53\u7624\u548c\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u7684\u514d\u75ab\u80bf\u7624\u5b66\u516c\u53f8\uff0c\u4eca\u5929\u5171\u540c\u5ba3\u5e03\u53cc\u65b9\u5df2\u8fbe\u6210\u4e00\u9879\u7814\u7a76\u534f\u8bae\uff0c\u4ee5\u8bc4\u4f30 Umoja \u7684 iCIL \u5e73\u53f0\u7ed3\u5408IASO \u7684\u4e1a\u754c\u6700\u4f18 CAR\uff0c\u5f00\u53d1\u5373\u7528\u578b\u7597\u6cd5\uff0c\u4e3a\u6025\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u53ca\u6f5c\u5728\u5176\u4ed6\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u60a3\u8005\uff0c\u63d0\u4f9b\u53ef\u8d1f\u62c5\u3001\u4fbf\u6377\u7684\u6cbb\u7597\u65b9\u6848\u3002 \u9a6f\u9e7f\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u6c6a\u6587\u535a\u58eb\u8868\u793a\uff1a"\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0eUmoja\u8fbe\u6210\u5408\u4f5c\u3002\u6211\u4eec\u7684\u5168\u4eba\u6e90 CAR \u7ed3\u6784\u7684\u4f18\u52bf\u5728\u9488\u5bf9\u591a\u4e2a\u9776\u70b9\uff0c\u5e7f\u6cdb\u8840\u6db2\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5df2\u7ecf\u5f97\u5230\u9a8c\u8bc1\u3002\u6211\u4eec\u5f88\u9ad8\u5174\u5c06\u6211\u4eec\u7684 CAR \u7ed3\u6784\u4e0e Umoja \u7684\u65b0\u578b ShRED \u6280\u672f\u76f8\u7ed3\u5408\uff0c\u4ee5\u66f4\u4f4e\u7684\u6210\u672c\u5f00\u53d1\u5373\u7528\u578b\u4e0b\u4e00\u4ee3\u65b0\u578b\u7ec6\u80de\u7597\u6cd5\u3002" \u9a6f\u9e7f\u751f\u7269\u5229\u7528\u5176\u4e13\u6709\u7684\u5168\u4eba\u6e90\u6297\u4f53\u53d1\u73b0\u5e73\u53f0\uff08IMARS\uff09\u3001\u9ad8\u901a\u91cf CAR \u7b5b\u9009\u5e73\u53f0\u3001\u5feb\u901f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6267\u884c\u529b\uff0c\u4ee5\u53ca\u81ea\u6709\u7684\u8d28\u7c92\u3001\u75c5\u6bd2\u8f7d\u4f53\u548c CAR-T \u7ec6\u80de\u751f\u4ea7\u6210\u529f\u7387\u5747\u8d85\u8fc790%\u7684GMP\u751f\u4ea7\u8bbe\u65bd\u6765\u7b5b\u9009\u6f5c\u5728\u4e1a\u754c\u6700\u4f18\u7684 CAR\u3002\u540c\u65f6\uff0c\u516c\u53f8\u4e5f\u81f4\u529b\u4e8e\u5c06\u5176\u521b\u65b0\u7597\u6cd5\u5e26\u7ed9\u5168\u7403\u66f4\u5e7f\u6cdb\u7684\u4eba\u7fa4\u3002 "\u6211\u4eec\u76f8\u4fe1\uff0c\u7ed3\u5408\u6211\u4eec\u7684 iCIL \u5e73\u53f0\u548c\u9a6f\u9e7f\u751f\u7269\u7684 CAR \u5f00\u53d1\u7684\u5373\u7528\u578b\u7597\u6cd5\u5c06\u4e3a\u66f4\u5e7f\u6cdb\u7684\u60a3\u8005\u83b7\u5f97\u8840\u6db2\u6076\u6027\u80bf\u7624\u7684\u6700\u4f18\u7597\u6cd5\u94fa\u5e73\u9053\u8def\uff0c"Umoja\u8054\u5408\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u6267\u884c\u5b98,\u533b\u5b66\u535a\u58eb Andy Scharenberg\u8bf4,"\u968f\u7740\u533b\u5b66\u548c\u79d1\u5b66\u7684\u8fdb\u6b65\uff0c\u764c\u75c7\u60a3\u8005\u7684\u6cbb\u7597\u65b9\u6cd5\u4e5f\u5728\u8fdb\u6b65\uff0c\u4f46\u6211\u4eec\u8fd8\u6709\u5f88\u957f\u7684\u8def\u8981\u8d70\u3002 Umoja 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