{"id":81559,"date":"2022-10-13T18:02:00","date_gmt":"2022-10-13T11:02:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022101318020081559"},"modified":"2022-10-14T22:35:15","modified_gmt":"2022-10-14T14:35:15","slug":"%e5%92%8c%e9%93%82%e5%8c%bb%e8%8d%af%e5%b0%86%e4%ba%8e%e7%ac%ac37%e5%b1%8a%e7%99%8c%e7%97%87%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e5%ad%a6%e4%bc%9a%e5%b9%b4%e4%bc%9a%e5%85%ac%e5%b8%83%e5%a4%9a%e9%a1%b9","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022101318020081559","title":{"rendered":"\u548c\u94c2\u533b\u836f\u5c06\u4e8e\u7b2c37\u5c4a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u5b66\u4f1a\u5e74\u4f1a\u516c\u5e03\u591a\u9879\u7814\u7a76\u6210\u679c"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/HB_for_email_Logo-17.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><p><span class=\"legendSpanClass\">\u4e2d\u56fd\u82cf\u5dde\u3001\u7f8e\u56fd\u9a6c\u585e\u8bf8\u585e\u5dde\u5251\u6865\u548c\u8377\u5170\u9e7f\u7279\u4e39<\/span><span class=\"legendSpanClass\">2022\u5e7410\u670813\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u548c\u94c2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a02142.HK\uff09\uff0c\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u80bf\u7624\u53ca\u514d\u75ab\u9886\u57df\u521b\u65b0\u6297\u4f53\u7597\u6cd5\u53d1\u73b0\u3001\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u5168\u7403\u751f\u7269\u533b\u836f\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u5e03\u5c06\u4e8e2022\u5e7411\u67088\u65e5\u81f312\u65e5\u5728\u7f8e\u56fd\u6ce2\u58eb\u987f\u53ca\u7ebf\u4e0a\u4e3e\u884c\u7684\u7b2c37\u5c4a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u5b66\u4f1a\uff08SITC\uff09\u5e74\u4f1a\u4e0a\uff0c\u4ee5\u58c1\u62a5\u5f62\u5f0f\u5c55\u793a\u516c\u53f8\u4e94\u9879\u7ba1\u7ebf\u4ea7\u54c1\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u6210\u679c\uff0c\u5305\u62ecHBM7008\u3001HBM7004\u3001HBM1047\u3001HBM1020\u548cHBM1022\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p><b>\u58c1\u62a5\u8be6\u60c5\uff1a<\/b><\/p>\n<p>\u6807\u9898\uff1aHBM1047, a novel fully human anti-CD200R1 antagonist antibody with potent anti-tumor efficacy in preclinical model<\/p>\n<p>\u7f16\u53f7\uff1a477<\/p>\n<p>\u6807\u9898\uff1aHBM7008 (B7H4x4-1BB HBICE) synergizes HBM7004 (B7H4xCD3 HBICE) for solid tumor therapy<\/p>\n<p>\u7f16\u53f7\uff1a858<\/p>\n<p>\u6807\u9898\uff1aHBM7008, a first-in-class bispecific antibody targeting both B7-H4 and 4-1BB, exhibits robust anti-tumor immunity and low toxicity through B7-H4-directed 4-1BB activation<\/p>\n<p>\u7f16\u53f7\uff1a1057<\/p>\n<p>\u6807\u9898\uff1aHBM1020 is a fully human novel anti-B7H7 antibody with excellent preclinical efficacy and safety profile<\/p>\n<p>\u7f16\u53f7\uff1a1075<\/p>\n<p>\u6807\u9898\uff1aHBM1022: an afucosylated anti-CCR8 antibody, depletes specifically tumor infiltrating Tregs and inhibits tumor growth with excellent safety profile in preclinical studies<\/p>\n<p>\u7f16\u53f7\uff1a1361<\/p>\n<p>\u5173\u4e8eSITC\u5e74\u4f1a\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u53ef\u8bbf\u95ee\u5176<a href=\"http:\/\/www.sitcancer.org\/\" target=\"_blank\" rel=\"nofollow noopener\">\u5b98\u65b9\u7f51\u7ad9<\/a>\u83b7\u53d6\u3002\u6458\u8981\u7684\u8be6\u7ec6\u5185\u5bb9\u5c06\u4e8e2022\u5e7411\u67087\u65e58:00\uff08\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f4\uff09\u5728\u5b98\u7f51\u516c\u5e03\uff0c\u6240\u6709\u58c1\u62a5\u5c06\u4e8e2022\u5e7411\u670810\u65e5\u81f311\u65e59:00\u81f321:00\uff08\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f4\uff09\u5728\u4f1a\u573a\u5c55\u793a\uff0c\u656c\u8bf7\u671f\u5f85\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u56fd\u82cf\u5dde\u3001\u7f8e\u56fd\u9a6c\u585e\u8bf8\u585e\u5dde\u5251\u6865\u548c\u8377\u5170\u9e7f\u7279\u4e392022\u5e7410\u670813\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u548c\u94c2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a02142.HK\uff09\uff0c\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u80bf\u7624\u53ca\u514d\u75ab\u9886\u57df\u521b\u65b0\u6297\u4f53\u7597\u6cd5\u53d1\u73b0\u3001\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u5168\u7403\u751f\u7269\u533b\u836f\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u5e03\u5c06\u4e8e2022\u5e7411\u67088\u65e5\u81f312\u65e5\u5728\u7f8e\u56fd\u6ce2\u58eb\u987f\u53ca\u7ebf\u4e0a\u4e3e\u884c\u7684\u7b2c37\u5c4a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u5b66\u4f1a\uff08SITC\uff09\u5e74\u4f1a\u4e0a\uff0c\u4ee5\u58c1\u62a5\u5f62\u5f0f\u5c55\u793a\u516c\u53f8\u4e94\u9879\u7ba1\u7ebf\u4ea7\u54c1\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u6210\u679c\uff0c\u5305\u62ecHBM7008\u3001HBM7004\u3001HBM1047\u3001HBM1020\u548cHBM1022\u3002 \u58c1\u62a5\u8be6\u60c5\uff1a \u6807\u9898\uff1aHBM1047, a novel fully human anti-CD200R1 antagonist antibody with potent anti-tumor efficacy in preclinical model \u7f16\u53f7\uff1a477 \u6807\u9898\uff1aHBM7008 (B7H4x4-1BB HBICE) synergizes HBM7004 (B7H4xCD3 HBICE) for solid tumor therapy \u7f16\u53f7\uff1a858 \u6807\u9898\uff1aHBM7008, a first-in-class bispecific antibody targeting both B7-H4 and 4-1BB, exhibits robust anti-tumor immunity and low toxicity through B7-H4-directed 4-1BB activation \u7f16\u53f7\uff1a1057&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2022101318020081559\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":8278,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-81559","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/81559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=81559"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/81559\/revisions"}],"predecessor-version":[{"id":81561,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/81559\/revisions\/81561"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/8278"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=81559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=81559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=81559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}