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Pharma\u3001\u767e\u5965\u6cf0\u6388\u6743\u7684\u80bf\u7624\u836f\u7269\u7684\u5546\u4e1a\u5316\u3002\u516c\u53f8\u4e5f\u901a\u8fc7\u4e0e\u5305\u62ecMirati Therapeutics\u3001Seagen\u4ee5\u53caZymeworks\u5728\u5185\u7684\u591a\u5bb6\u516c\u53f8\u5408\u4f5c\uff0c\u66f4\u5927\u7a0b\u5ea6\u5730\u6ee1\u8db3\u5f53\u524d\u5168\u7403\u8303\u56f4\u5c1a\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002<\/p>\n<p>2021\u5e741\u6708\uff0c\u767e\u6d4e\u795e\u5dde\u548c\u8bfa\u534e\u5ba3\u5e03\u8fbe\u6210\u5408\u4f5c\uff0c\u6388\u4e88\u8bfa\u534e\u5728\u5317\u7f8e\u3001\u6b27\u6d32\u548c\u65e5\u672c\u5171\u540c\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u5546\u4e1a\u5316\u767e\u6d4e\u795e\u5dde\u7684\u6297PD-1\u6297\u4f53\u836f\u7269\u767e\u6cfd\u5b89<sup>&reg;<\/sup>\uff08\u66ff\u96f7\u5229\u73e0\u5355\u6297\uff09\u7684\u6743\u76ca\u3002\u57fa\u4e8e\u8fd9\u4e00\u5353\u6709\u6210\u6548\u7684\u5408\u4f5c\uff0c\u767e\u6d4e\u795e\u5dde\u548c\u8bfa\u534e\u4e8e2021\u5e7412\u6708\u5ba3\u5e03\u4e86\u5173\u4e8e\u6b63\u57283\u671f\u5f00\u53d1\u7684TIGIT\u6291\u5236\u5242\u6b27\u53f8\u73c0\u5229\u5355\u6297\u7684\u9009\u62e9\u6743\u3001\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\u3002\u8bfa\u534e\u548c\u767e\u6d4e\u795e\u5dde\u8fd8\u7b7e\u8ba2\u4e86\u4e00\u9879\u6218\u7565\u5546\u4e1a\u534f\u8bae\uff0c\u6839\u636e\u8be5\u534f\u8bae\uff0c\u767e\u6d4e\u795e\u5dde\u5c06\u5728\u4e2d\u56fd\u6307\u5b9a\u533a\u57df\u63a8\u5e7f5\u6b3e\u5df2\u83b7\u6279\u7684\u8bfa\u534e\u6297\u80bf\u7624\u836f\u7269\u3002<\/p>\n<p><b>\u5173\u4e8e\u767e\u6d4e\u795e\u5dde<\/b><\/p>\n<p>\u767e\u6d4e\u795e\u5dde\u662f\u4e00\u5bb6\u5168\u7403\u6027\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u521b\u65b0\u3001\u53ef\u8d1f\u62c5\u7684\u6297\u80bf\u7624\u836f\u7269\uff0c\u65e8\u5728\u4e3a\u5168\u7403\u60a3\u8005\u6539\u5584\u6cbb\u7597\u6548\u679c\u3001\u63d0\u9ad8\u836f\u7269\u53ef\u53ca\u6027\u3002\u901a\u8fc7\u5f3a\u5927\u7684\u81ea\u4e3b\u7814\u53d1\u80fd\u529b\u548c\u5916\u90e8\u6218\u7565\u5408\u4f5c\uff0c\u6211\u4eec\u4e0d\u65ad\u52a0\u901f\u5f00\u53d1\u591a\u5143\u3001\u521b\u65b0\u7684\u836f\u7269\u7ba1\u7ebf\u3002\u6211\u4eec\u81f4\u529b\u4e8e\u4e3a\u5168\u7403\u66f4\u591a\u60a3\u8005\u5168\u9762\u6539\u5584\u836f\u7269\u53ef\u53ca\u6027\u3002\u767e\u6d4e\u795e\u5dde\u5728\u5168\u7403\u4e94\u5927\u6d32\u6253\u9020\u4e86\u4e00\u652f\u8d85\u8fc78,500\u4eba\u7684\u56e2\u961f\uff0c\u5e76\u5728\u4e2d\u56fd\u5317\u4eac\u3001\u7f8e\u56fd\u9ebb\u7701\u5251\u6865\u548c\u745e\u58eb\u5df4\u585e\u5c14\u8bbe\u7acb\u4e86\u4e3b\u8981\u529e\u4e8b\u5904\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee<a href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https:\/\/www.beigene.com\/&amp;esheet=52806095&amp;newsitemid=20220809005409&amp;lan=en-US&amp;anchor=www.beigene.com&amp;index=2&amp;md5=0dbb1f1aaf301923d0f61ecf28db6383\" target=\"_blank\" rel=\"nofollow noopener\">http:\/\/www.beigene.com.cn<\/a>\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u5305\u542b\u300a1995\u5e74\u79c1\u4eba\u8bc1\u5238\u8bc9\u8bbc\u6539\u9769\u6cd5\u6848\u300b\uff08Private Securities Litigation Reform Act of 1995\uff09\u4ee5\u53ca\u5176\u4ed6\u8054\u90a6\u8bc1\u5238\u6cd5\u5f8b\u4e2d\u5b9a\u4e49\u7684\u524d\u77bb\u6027\u58f0\u660e\uff0c\u5305\u62ec\u6709\u5173\u767e\u60a6\u6cfd<sup>&reg;<\/sup>&nbsp;\u4e3a\u8fb9\u7f18\u533a\u6dcb\u5df4\u7624\u60a3\u8005\u63d0\u4f9b\u4e34\u5e8a\u83b7\u76ca\u7684\u6f5c\u529b\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u672a\u6765\u5728\u6b27\u76df\u5730\u533a\u548c\u5176\u4ed6\u5e02\u573a\u5f00\u5c55\u7684\u5f00\u53d1\u3001\u836f\u653f\u7533\u62a5\u53ca\u83b7\u6279\u3001\u5546\u4e1a\u5316\u548c\u5e02\u573a\u51c6\u5165\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u6f5c\u5728\u7684\u5546\u4e1a\u5316\u673a\u4f1a\uff0c\u4ee5\u53ca\u767e\u6d4e\u795e\u5dde\u5728&quot;\u5173\u4e8e\u767e\u6d4e\u795e\u5dde\u80bf\u7624\u5b66&quot;\u548c&quot;\u5173\u4e8e\u767e\u6d4e\u795e\u5dde&quot;\u6807\u9898\u4e0b\u63d0\u53ca\u7684\u767e\u6d4e\u795e\u5dde\u7684\u8ba1\u5212\u3001\u627f\u8bfa\u3001\u62b1\u8d1f\u548c\u76ee\u6807\u3002\u7531\u4e8e\u5404\u79cd\u91cd\u8981\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4e0e\u524d\u77bb\u6027\u58f0\u660e\u4e2d\u7684\u7ed3\u679c\u5b58\u5728\u5b9e\u8d28\u6027\u5dee\u5f02\u3002\u8fd9\u4e9b\u56e0\u7d20\u5305\u62ec\uff1a\u767e\u6d4e\u795e\u5dde\u8bc1\u660e\u5176\u5019\u9009\u836f\u7269\u529f\u6548\u548c\u5b89\u5168\u6027\u7684\u80fd\u529b\uff1b\u5176\u5019\u9009\u836f\u7269\u7684\u4e34\u5e8a\u7ed3\u679c\u53ef\u80fd\u4e0d\u652f\u6301\u8fdb\u4e00\u6b65\u5f00\u53d1\u6216\u4e0a\u5e02\u6279\u51c6\uff1b\u836f\u653f\u90e8\u95e8\u7684\u884c\u52a8\u53ef\u80fd\u4f1a\u5f71\u54cd\u5230\u4e34\u5e8a\u8bd5\u9a8c\u7684\u542f\u52a8\u3001\u65f6\u95f4\u8868\u548c\u8fdb\u5c55\u4ee5\u53ca\u836f\u7269\u4e0a\u5e02\u5ba1\u6279\uff1b\u767e\u6d4e\u795e\u5dde\u7684\u4e0a\u5e02\u836f\u7269\u53ca\u5019\u9009\u836f\u7269\uff08\u5982\u80fd\u83b7\u6279\uff09\u83b7\u5f97\u5546\u4e1a\u6210\u529f\u7684\u80fd\u529b\uff1b\u767e\u6d4e\u795e\u5dde\u83b7\u5f97\u548c\u7ef4\u62a4\u5bf9\u5176\u836f\u7269\u548c\u6280\u672f\u7684\u77e5\u8bc6\u4ea7\u6743\u4fdd\u62a4\u7684\u80fd\u529b\uff1b\u767e\u6d4e\u795e\u5dde\u4f9d\u8d56\u7b2c\u4e09\u65b9\u8fdb\u884c\u836f\u7269\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u5176\u4ed6\u670d\u52a1\u7684\u60c5\u51b5\uff1b\u767e\u6d4e\u795e\u5dde\u53d6\u5f97\u76d1\u7ba1\u5ba1\u6279\u548c\u5546\u4e1a\u5316\u533b\u836f\u4ea7\u54c1\u7684\u6709\u9650\u7ecf\u9a8c\uff0c\u53ca\u5176\u83b7\u5f97\u8fdb\u4e00\u6b65\u7684\u8425\u8fd0\u8d44\u91d1\u4ee5\u5b8c\u6210\u5019\u9009\u836f\u7269\u5f00\u53d1\u3001\u5546\u4e1a\u5316\u53ca\u5b9e\u73b0\u5e76\u4fdd\u6301\u76c8\u5229\u7684\u80fd\u529b\uff1b\u65b0\u51a0\u80ba\u708e\u5168\u7403\u75ab\u60c5\u5bf9\u767e\u6d4e\u795e\u5dde\u7684\u4e34\u5e8a\u5f00\u53d1\u3001\u76d1\u7ba1\u3001\u5546\u4e1a\u5316\u8fd0\u8425\u3001\u751f\u4ea7\u4ee5\u53ca\u5176\u4ed6\u4e1a\u52a1\u5e26\u6765\u7684\u5f71\u54cd\uff1b\u4ee5\u53ca\u767e\u6d4e\u795e\u5dde\u5728\u6700\u8fd1\u5b63\u5ea6\u62a5\u544a\u768410-Q\u8868\u683c\u4e2d&quot;\u98ce\u9669\u56e0\u7d20&quot;\u7ae0\u8282\u91cc\u66f4\u5168\u9762\u8ba8\u8bba\u7684\u5404\u7c7b\u98ce\u9669\uff1b\u4ee5\u53ca\u767e\u6d4e\u795e\u5dde\u5411\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\u671f\u540e\u5448\u62a5\u4e2d\u5173\u4e8e\u6f5c\u5728\u98ce\u9669\u3001\u4e0d\u786e\u5b9a\u6027\u4ee5\u53ca\u5176\u4ed6\u91cd\u8981\u56e0\u7d20\u7684\u8ba8\u8bba\u3002\u672c\u65b0\u95fb\u7a3f\u4e2d\u7684\u6240\u6709\u4fe1\u606f\u4ec5\u53ca\u4e8e\u65b0\u95fb\u7a3f\u53d1\u5e03\u4e4b\u65e5\uff0c\u9664\u975e\u6cd5\u5f8b\u8981\u6c42\uff0c\u767e\u6d4e\u795e\u5dde\u5e76\u65e0\u8d23\u4efb\u66f4\u65b0\u8be5\u7b49\u4fe1\u606f\u3002<\/p>\n[i]&nbsp;Annals of Oncology, Marginal Zone Lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up,&nbsp;January 6, 2020<br \/>[ii]&nbsp;Smith, A., et al., <i>Lymphoma incidence, survival and prevalence 2004-2014: sub-type analyses from the UK&#8217;s Haematological Malignancy Research Network.<\/i> Br J Cancer, 2015. 112(9): p. 1575-84.<br \/>[iii]&nbsp;Smith, A., et al., <i>Lymphoma incidence, survival and prevalence 2004-2014: sub-type analyses from the UK&#8217;s Haematological Malignancy Research Network.<\/i> Br J Cancer, 2015. 112(9): p. 1575-84.<br \/>[iv]&nbsp;Maynadie, M., et al., <i>Splenic Marginal Zone Lymphoma: French Registries Population-Based Treatment and Survival <\/i>Analyses (2002-2014). Blood, 2020. 136.<br \/>[v] Leukemia &amp; Lymphoma Society, Marginal Zone Lymphoma. Available at: <a href=\"https:\/\/www.lls.org\/research\/marginal-zone-lymphoma-mzl\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.lls.org\/research\/marginal-zone-lymphoma-mzl<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eba\u7528\u836f\u54c1\u59d4\u5458\u4f1a\uff08CHMP\uff09\u63a8\u8350\u6279\u51c6\u767e\u60a6\u6cfd&reg;\u7528\u4e8e\u590d\u53d1\u6216\u96be\u6cbb\u6027\u8fb9\u7f18\u533a\u6dcb\u5df4\u7624\u7684\u6cbb\u7597 \u5982\u679c\u83b7\u6279\uff0c\u767e\u60a6\u6cfd&reg;\u5c06\u6210\u4e3a\u6b27\u6d32\u9996\u4e2a\u4e14\u552f\u4e00\u7528\u4e8e\u8fb9\u7f18\u533a\u6dcb\u5df4\u7624\u6cbb\u7597\u7684\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5242 \u4e2d\u56fd\u5317\u4eac\uff0c\u7f8e\u56fd\u9ebb\u7701\u5251\u6865\u548c\u745e\u58eb\u5df4\u585e\u5c142022\u5e749\u670819\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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[i]&nbsp;Annals of Oncology, Marginal Zone Lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2022091918000080320\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":8278,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-80320","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/80320","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=80320"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/80320\/revisions"}],"predecessor-version":[{"id":80321,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/80320\/revisions\/80321"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/8278"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=80320"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=80320"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=80320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}