{"id":78044,"date":"2022-08-31T07:30:00","date_gmt":"2022-08-31T00:30:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022083107300078044"},"modified":"2022-08-31T22:15:18","modified_gmt":"2022-08-31T14:15:18","slug":"%e8%af%ba%e8%af%9a%e5%81%a5%e5%8d%8e%e5%ae%a3%e5%b8%83tafasitamab%e8%81%94%e5%90%88%e6%9d%a5%e9%82%a3%e5%ba%a6%e8%83%ba%e6%b2%bb%e7%96%97%e5%a4%8d%e5%8f%91-%e9%9a%be%e6%b2%bbdlbcl%e7%9a%84%e4%b8%8a","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022083107300078044","title":{"rendered":"\u8bfa\u8bda\u5065\u534e\u5ba3\u5e03Tafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbbDLBCL\u7684\u4e0a\u5e02\u7533\u8bf7\u83b7\u9999\u6e2f\u53d7\u7406"},"content":{"rendered":"

\u5317\u4eac<\/span>2022\u5e748\u670831\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u751f\u7269\u533b\u836f\u9ad8\u79d1\u6280\u516c\u53f8\u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u4eca\u5929\u5ba3\u5e03\uff0ctafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u6cbb\u7597\u4e0d\u9002\u5408\u81ea\u4f53\u5e72\u7ec6\u80de\u79fb\u690d\u6761\u4ef6\u7684\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u6210\u4eba\u60a3\u8005\u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\u5df2\u83b7\u9999\u6e2f\u536b\u751f\u7f72\u53d7\u7406\u3002<\/p>\n

\u8bfa\u8bda\u5065\u534e\u8054\u5408\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517cCEO\u5d14\u9701\u677e\u535a\u58eb\u8bf4\uff1a"\u6b64\u6b21\u9999\u6e2f\u4e0a\u5e02\u7533\u8bf7\uff08BLA\uff09\u83b7\u53d7\u7406\u662ftafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u7684\u53c8\u4e00\u91cd\u8981\u8fdb\u5c55\uff0c\u6b64\u524dtafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u5df2\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u5f00\u5c55\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8fd9\u8fdb\u4e00\u6b65\u4f53\u73b0\u6211\u4eec\u4e3a\u5927\u4e2d\u534e\u533a\u60a3\u8005\u5e26\u6765\u521b\u65b0\u7597\u6cd5\u7684\u627f\u8bfa\uff0c\u5e0c\u671btafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u80fd\u65e9\u65e5\u6ee1\u8db3DLBCL\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u9700\u6c42\u3002"<\/p>\n

Tafasitamab \u662f\u4e00\u6b3e\u9776\u5411CD19\u7684Fc\u7ed3\u6784\u57df\u4f18\u5316\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u9664\u5728\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u7b26\u5408\u6761\u4ef6\u7684DLBCL\u60a3\u8005\uff0ctafasitamab\u5c1a\u672a\u5728\u4e2d\u56fd\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u4efb\u4f55\u9002\u5e94\u75c7\u3002\u4eca\u5e747\u6708\uff0ctafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbbDLBCL\u5728\u535a\u9ccc\u4e50\u57ce\u5f00\u51fa\u9996\u65b9\u3002<\/p>\n

Tafasitamab\u5df2\u83b7\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u4ee5\u53ca\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u6709\u6761\u4ef6\u6279\u51c6\u4e0e\u6765\u90a3\u5ea6\u80fa\u8054\u5408\u6cbb\u7597\u4e0d\u9002\u5408\u81ea\u4f53\u5e72\u7ec6\u80de\u79fb\u690d\u6761\u4ef6\u7684\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u60a3\u8005\u3002<\/p>\n

\u5173\u4e8e<\/b> tafasitamab<\/b><\/p>\n

Tafasitamab \u662f\u4e00\u6b3e\u9776\u5411CD19\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\u3002<\/p>\n

2010 \u5e74\uff0cMorphoSys \u516c\u53f8\u4eceXencor\u516c\u53f8\u83b7\u5f97\u5168\u7403\u72ec\u5bb6\u5f00\u53d1\u548c\u5546\u4e1a\u5316tafasitamab\u7684\u6743\u5229\u3002<\/p>\n

Tafasitamab \u5305\u542b Xencor \u516c\u53f8\u72ec\u6709\u7684XmAb®<\/sup> \u5de5\u7a0b\u5316 Fc \u7ed3\u6784\u57df\uff0c\u56e0\u6b64\u663e\u8457\u5f3a\u5316\u4e86\u6297\u4f53\u4f9d\u8d56\u6027\u7ec6\u80de\u4ecb\u5bfc\u7684\u7ec6\u80de\u6bd2\u4f5c\u7528\uff08ADCC\uff09\u548c\u6297\u4f53\u4f9d\u8d56\u6027\u7ec6\u80de\u541e\u566c\u4f5c\u7528\uff08ADCP\uff09\uff0c\u901a\u8fc7\u7ec6\u80de\u51cb\u4ea1\u548c\u514d\u75ab\u6548\u5e94\u673a\u5236\u4ecb\u5bfc B \u7ec6\u80de\u80bf\u7624\u7684\u88c2\u89e3\u3002<\/p>\n

\u5728\u7f8e\u56fd\uff0cMonjuvi®<\/sup> (tafasitamab-cxix) \u88ab\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u4e0e\u6765\u90a3\u5ea6\u80fa\u8054\u5408\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u6027\u5927 B \u7ec6\u80de\u6dcb\u5df4\u7624 (DLBCL) \u6210\u4eba\u60a3\u8005\uff08\u672a\u660e\u786e\u6307\u5b9a\uff09\uff0c\u5305\u62ec\u7531\u4f4e\u6076\u6027\u6dcb\u5df4\u7624\u6f14\u8fdb\u800c\u6765\u7684 DLBCL \uff0c\u4ee5\u53ca\u4e0d\u9002\u5408\u81ea\u4f53\u5e72\u7ec6\u80de\u79fb\u690d\u6761\u4ef6\u7684\u60a3\u8005\u3002\u57fa\u4e8e\u603b\u7f13\u89e3\u7387\uff08ORR\uff09\uff0c\u8be5\u9002\u5e94\u75c7\u83b7\u5f97\u52a0\u901f\u6279\u51c6\u3002\u5bf9\u8be5\u9002\u5e94\u75c7\u7684\u540e\u7eed\u6279\u51c6\u53ef\u80fd\u53d6\u51b3\u4e8e\u9a8c\u8bc1\u6027\u8bd5\u9a8c\u4e2d\u5bf9\u4e34\u5e8a\u76ca\u5904\u7684\u9a8c\u8bc1\u3002<\/p>\n

\u5728\u6b27\u6d32\uff0cMinjuvi®<\/sup> (tafasitamab) \u4e0e\u6765\u90a3\u5ea6\u80fa\u8054\u5408\uff0c\u4e4b\u540e\u662fMinjuvi\u7684\u5355\u836f\u6cbb\u7597\uff0c\u5df2\u83b7\u6709\u6761\u4ef6\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u4e0d\u7b26\u5408\u81ea\u4f53\u5e72\u7ec6\u80de\u79fb\u690d\u6761\u4ef6\u7684\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u6210\u4eba\u60a3\u8005\u3002<\/p>\n

\u4f5c\u4e3a B \u7ec6\u80de\u6076\u6027\u80bf\u7624\u7684\u6cbb\u7597\u9009\u62e9\uff0ctafasitamab\u6b63\u5728\u5f00\u5c55\u591a\u9879\u8054\u5408\u7528\u836f\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n

Monjuvi®<\/sup> \u548cMinjuvi®<\/sup> \u662f MorphoSys \u516c\u53f8\u7684\u6ce8\u518c\u5546\u6807\u3002\u5728\u7f8e\u56fd\uff0ctafasitamab \u7531Incyte\u548cMorphoSys\u4ee5Monjuvi®<\/sup> \u54c1\u724c\u5171\u540c\u9500\u552e\uff1b\u5728\u6b27\u6d32\u3001\u82f1\u56fd\u548c\u52a0\u62ff\u5927\uff0cIncyte\u4ee5 Minjuvi®<\/sup>\u54c1\u724c\u9500\u552e\u3002\u6309\u7167\u548cMorphoSys\u8fbe\u6210\u7684\u534f\u8bae\uff0cIncyte\u83b7\u5f97\u7f8e\u56fd\u5e02\u573a\u4ee5\u5916\u72ec\u5bb6\u5546\u4e1a\u5316tafasitamab\u7684\u6743\u5229\u30022021\u5e748\u6708\uff0c\u8bfa\u8bda\u5065\u534e\u548cIncyte\u5c31tafasitamab\u5728\u5927\u4e2d\u534e\u533a\u7684\u8840\u6db2\u7624\u548c\u5b9e\u4f53\u7624\u5f00\u53d1\u548c\u72ec\u5bb6\u5546\u4e1a\u5316\u7b7e\u8ba2\u4e86\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\u3002<\/p>\n

XmAb®<\/sup> \u662fXencor\u516c\u53f8\u7684\u6ce8\u518c\u5546\u6807\u3002<\/p>\n

\u5173\u4e8e\u8bfa\u8bda\u5065\u534e<\/b><\/p>\n

\u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u662f\u4e00\u5bb6\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u751f\u7269\u533b\u836f\u9ad8\u79d1\u6280\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u6cbb\u7597\u9886\u57df\u7684\u4e00\u7c7b\u65b0\u836f\u7814\u5236\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u6dcb\u5df4\u7624\u3001\u5b9e\u4f53\u7624\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u73b0\u6709\u591a\u4e2a\u65b0\u836f\u4ea7\u54c1\u5904\u4e8e\u5546\u4e1a\u5316\u3001\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u7814\u53d1\u9636\u6bb5\u3002\u516c\u53f8\u5728\u5317\u4eac\u3001\u5357\u4eac\u3001\u4e0a\u6d77\u3001\u5e7f\u5dde\u3001\u9999\u6e2f\u4ee5\u53ca\u7f8e\u56fd\u8bbe\u6709\u5206\u652f\u673a\u6784\u3002<\/p>\n

\u8bfa\u8bda\u5065\u534e\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n

\u672c\u65b0\u95fb\u7a3f\u542b\u6709\u4e00\u4e9b\u524d\u77bb\u6027\u58f0\u660e\u7684\u62ab\u9732\u3002\u9664\u5bf9\u4e8b\u5b9e\u7684\u9648\u8ff0\u4ee5\u5916\uff0c\u6240\u6709\u5176\u4ed6\u58f0\u660e\u53ef\u88ab\u770b\u4f5c\u662f\u524d\u77bb\u6027\u58f0\u660e\uff0c\u5373\u5173\u4e8e\u6211\u4eec\u6216\u8005\u6211\u4eec\u7684\u7ba1\u7406\u90e8\u95e8\u6253\u7b97\u3001\u671f\u671b\u3001\u8ba1\u5212\u3001\u76f8\u4fe1\u6216\u8005\u9884\u671f\u5c06\u4f1a\u6216\u8005\u53ef\u80fd\u4f1a\u5728\u672a\u6765\u53d1\u751f\u7684\u884c\u4e3a\u3001\u4e8b\u4ef6\u6216\u8005\u53d1\u5c55\u6240\u505a\u51fa\u7684\u58f0\u660e\u3002\u6b64\u7c7b\u58f0\u660e\u662f\u6211\u4eec\u7684\u7ba1\u7406\u90e8\u95e8\u6839\u636e\u5176\u7ecf\u9a8c\u548c\u5bf9\u5386\u53f2\u8d8b\u52bf\u3001\u5f53\u524d\u6761\u4ef6\u3001\u9884\u671f\u672a\u6765\u53d1\u5c55\u548c\u5176\u4ed6\u76f8\u5173\u56e0\u7d20\u7684\u8ba4\u77e5\uff0c\u505a\u51fa\u7684\u5047\u8bbe\u4e0e\u4f30\u8ba1\u3002\u8be5\u524d\u77bb\u6027\u58f0\u660e\u5e76\u4e0d\u80fd\u4fdd\u8bc1\u672a\u6765\u7684\u4e1a\u7ee9\uff0c\u5b9e\u9645\u7684\u7ed3\u679c\uff0c\u53d1\u5c55\u548c\u4e1a\u52a1\u51b3\u7b56\u53ef\u80fd\u4e0e\u8be5\u524d\u77bb\u6027\u58f0\u660e\u7684\u8bbe\u60f3\u4e0d\u7b26\u3002\u6211\u4eec\u7684\u524d\u77bb\u6027\u58f0\u660e\u540c\u6837\u53d7\u5230\u5927\u91cf\u7684\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u56e0\u7d20\u7684\u5236\u7ea6\uff0c\u8fd9\u53ef\u80fd\u4f1a\u5f71\u54cd\u6211\u4eec\u7684\u8fd1\u671f\u4ee5\u53ca\u957f\u671f\u7684\u4e1a\u7ee9\u8868\u73b0\u3002<\/p>\n

\u76f8\u5173\u94fe\u63a5\uff1ahttps:\/\/cn.innocarepharma.com\/cn\/<\/a><\/span><\/p>\n

\u8054\u7cfb\u4eba<\/b>:<\/b><\/p>\n

\n\n\n\n\n
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\u5a92\u4f53<\/b><\/span><\/p>\n<\/td>\n

<\/td>\n\n

\u6295\u8d44\u8005<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u9646\u6625\u534e<\/span><\/p>\n<\/td>\n

\n

86+10-66609879<\/span><\/p>\n

chunhua.lu@innocarepharma.com<\/a><\/span>  <\/span><\/p>\n<\/td>\n

\n

86+10-66609999<\/span><\/p>\n

ir@Innocarepharma.com<\/a><\/span> <\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n","protected":false},"excerpt":{"rendered":"

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