{"id":76257,"date":"2022-08-17T18:37:00","date_gmt":"2022-08-17T11:37:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022081718370076257"},"modified":"2022-08-17T22:13:50","modified_gmt":"2022-08-17T14:13:50","slug":"kronos%e5%92%8cinvivoscribe%e5%90%88%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022081718370076257","title":{"rendered":"Kronos\u548cInvivoscribe\u5408\u4f5c"},"content":{"rendered":"

\u53cc\u65b9\u5408\u4f5c\u7684\u4f34\u968f<\/i>\u8bca\u65ad\u5c06\u5728<\/i>Entospletinib<\/i>\u83b7\u5f97\u6f5c\u5728\u76d1\u7ba1\u6279\u51c6\u540e\uff0c\u7528\u6765\u7b5b\u67e5\u5927\u7ea6\u4e09\u5206\u4e4b\u4e00\u7684<\/i>AML<\/i>\u60a3\u8005\u4e2d\u5b58\u5728\u7684<\/i>NPM1<\/i>\u7a81<\/i>\u53d8<\/i><\/p>\n

Endosplestinib<\/i>\u76ee\u524d\u6b63\u5728<\/i>3<\/i>\u671f<\/i>AGILITY<\/i>\u6ce8\u518c\u7814\u7a76\u4e2d<\/i>\u8fdb\u884c\u7814\u7a76\uff0c\u9884\u8ba1\u6570\u636e\u5c06\u4e8e<\/i>2023<\/i>\u5e74\u4e0b\u534a\u5e74\u516c\u5e03<\/i><\/p>\n

\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u5723\u9a6c\u7279\u5965\u548c\u5723\u5730\u4e9a\u54e5<\/span>2022\u5e748\u670817\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u81f4\u529b\u4e8e\u6539\u53d8\u764c\u75c7\u60a3\u8005\u751f\u6d3b\u7684\u516c\u53f8Kronos Bio, Inc.\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aKRON\uff09\u4e0e\u80bf\u7624\u5b66\u8bca\u65ad\u8bd5\u5242\u76d2\u548c\u670d\u52a1\u7684\u5168\u7403\u63d0\u4f9b\u5546Invivoscribe\u4eca\u5929\u5ba3\u5e03\u4e00\u9879\u534f\u8bae\uff0c\u5f00\u53d1\u4e00\u79cd\u4e0eKronos Bio\u7684\u7814\u7a76\u6027\u7597\u6cd5Entospletinib\u4e00\u8d77\u4f7f\u7528\u7684\u4f34\u968f\u8bca\u65ad\uff08CDx\uff09\u3002Endosplestinib\u662fKronos Bio\u7684\u9886\u5148\u4e34\u5e8a\u5316\u5408\u7269\uff0c\u76ee\u524d\u6b63\u5728\u8fdb\u884c3\u671f\u6ce8\u518cAGILITY\u7814\u7a76\uff0c\u7528\u4e8e\u6cbb\u7597\u65b0\u8bca\u65ad\u7684NPM1\u7a81\u53d8\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08AML\uff09\u3002<\/p>\n

\"\"<\/a>
<\/span> <\/div>\n

\u8fd9\u9879\u8bca\u65ad\u5c06\u5bf9NPM1\u7a81\u53d8\u8fdb\u884c\u7b5b\u67e5\uff0c\u8be5\u7a81\u53d8\u5728\u5927\u7ea6\u4e09\u5206\u4e4b\u4e00\u7684AML\u60a3\u8005\u4e2d\u5b58\u5728\u3002<\/p>\n

\u5728\u8fc7\u53bb\u4e00\u5e74\u4e2d\uff0c\u8fd9\u4e24\u5bb6\u516c\u53f8\u5171\u540c\u52aa\u529b\u5f00\u53d1\u548c\u63a8\u8fdb\u8bca\u65ad\uff0c\u5e76\u51c6\u5907\u5728\u63d0\u4ea4Endospletanib"\u65b0\u836f\u7533\u8bf7"\uff08NDA\uff09\u7684\u540c\u65f6\uff0c\u5411\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u63d0\u4ea4"\u4e0a\u5e02\u524d\u6279\u51c6"\uff08PMA\uff09\u7533\u8bf7\u3002FDA\u8981\u6c42\u5bf9\u4f34\u968f\u8bca\u65ad\u8fdb\u884c\u9a8c\u8bc1\u548c\u6279\u51c6\uff08\u4f34\u968f\u8bca\u65ad\u7528\u4e8e\u9009\u62e9\u63a5\u53d7\u7279\u5b9a\u6cbb\u7597\u5242\u6cbb\u7597\u7684\u60a3\u8005\uff09\u3002<\/p>\n

\u8be5\u534f\u8bae\u4ee5Invivoscribe\u7684\u7ecf\u9a8c\u4e3a\u57fa\u7840\uff0cInvivoscribe\u5728\u5f00\u53d1\u8bca\u65ad\u65b9\u6cd5\u7528\u4e8e\u8bc6\u522b\u57fa\u56e0\u7a81\u53d8\u7684AML\u60a3\u8005\u548c\u83b7\u5f97\u8ba4\u8bc1\u65b9\u9762\u62e5\u6709\u7ecf\u9a8c\u3002Invivoscribe\u9500\u552e\u7528\u4e8eFLT3\u7a81\u53d8AML\u7684\u7ecfFDA\u6279\u51c6\u7684CDx\u3002<\/p>\n

Invivoscribe\u9996\u5e2d\u79d1\u5b66\u5b98\u517c\u9996\u5e2d\u6267\u884c\u5b98Jeffrey Miller\u535a\u58eb\u8868\u793a\uff1a"\u4e0eKronos Bio\u5408\u4f5c\u5f00\u5c55\u7684\u8fd9\u9879\u4f34\u968f\u8bca\u65adNPM1\u7a81\u53d8\u5316\u9a8c\u5f00\u53d1\u5de5\u4f5c\u662f\u6211\u4eec\u516c\u53f8\u7684\u4e00\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\u3002\u4f34\u968f\u8bca\u65ad\u5728\u9776\u5411\u836f\u7269\u7597\u6cd5\u7684\u5f00\u53d1\u548c\u6279\u51c6\u4e2d\u53d1\u6325\u7740\u5173\u952e\u4f5c\u7528\uff0c\u6b64\u7c7b\u5408\u4f5c\u5173\u7cfb\u5bf9\u4e8e\u6539\u5584\u764c\u75c7\u60a3\u8005\u7684\u62a4\u7406\u81f3\u5173\u91cd\u8981\u3002"<\/p>\n

Kronos Bio\u7684AGILITY\u8bd5\u9a8c\u65e8\u5728\u8bc4\u4f30Entospletinib\u5728\u65b0\u8bca\u65ad\u60a3\u6709NPM1\u7a81\u53d8AML\u7684\u7ea6180\u540d\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u5728\u8bd5\u9a8c\u4e2d\uff0c\u60a3\u8005\u5c06\u968f\u673a\u63a5\u53d7Endospletinib\u6216\u5b89\u6170\u5242\uff0c\u5e76\u7ed3\u5408\u6807\u51c6\u8bf1\u5bfc\u548c\u5de9\u56fa\u5316\u7597\u3002\u8bd5\u9a8c\u7684\u4e3b\u8981\u7ec8\u70b9\u662f\u53ef\u8861\u91cf\u7684\u6b8b\u7559\u75be\u75c5\uff08MRD\uff09\u7684\u8d1f\u9762\u5b8c\u6574\u53cd\u5e94\u3002\u65e0\u4e8b\u4ef6\u751f\u5b58\u7387\uff08EFS\uff09\u662f\u4e00\u4e2a\u5173\u952e\u7684\u6b21\u8981\u7ec8\u70b9\uff0c\u9884\u8ba1\u6210\u719f\u7684EFS\u6570\u636e\u5c06\u7528\u4e8e\u652f\u6301\u6f5c\u5728\u7684\u5168\u9762\u6279\u51c6\u3002<\/p>\n

Kronos Bio\u9996\u5e2d\u533b\u5b66\u5b98\u517c\u4e34\u5e8a\u5f00\u53d1\u6267\u884c\u526f\u603b\u88c1Jorge DiMartino\u533b\u5b66\u535a\u58eb\u548c\u54f2\u5b66\u535a\u58eb\u8868\u793a\uff1a"NPM1\u7a81\u53d8\u4f34\u968f\u8bca\u65ad\u7684\u5f00\u53d1\u662f\u6211\u4eec\u5feb\u901f\u63a8\u8fdbEntospletinib\u5de5\u4f5c\u7684\u5173\u952e\u4e00\u6b65\u3002\u6211\u4eec\u5f88\u5e78\u8fd0\u80fd\u591f\u4eceInvivoscribe\u4ee5\u5f80\u5728\u4e3aAML\u60a3\u8005\u63d0\u4f9b\u4f34\u968f\u8bca\u65ad\u7684\u7ecf\u9a8c\u4e2d\u53d7\u76ca\u3002"<\/p>\n

\u5173\u4e8e<\/b>Kronos Bio, Inc.<\/b><\/p>\n

Kronos Bio\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u53d1\u73b0\u548c\u5f00\u53d1\u65e8\u5728\u6539\u53d8\u764c\u75c7\u60a3\u8005\u751f\u6d3b\u7684\u7597\u6cd5\u3002\u516c\u53f8\u4e13\u6ce8\u4e8e\u9776\u5411\u5931\u8c03\u7684\u8f6c\u5f55\u56e0\u5b50\u548c\u7ec6\u80de\u5185\u63a8\u52a8\u764c\u589e\u957f\u7684\u8c03\u63a7\u7f51\u7edc\u3002Kronos Bio\u7684\u4e3b\u8981\u7814\u7a76\u7597\u6cd5\u662fEntospletinib\uff0c\u8fd9\u662f\u4e00\u79cd\u6b63\u5728\u5f00\u53d1\u4e2d\u7684\u9776\u5411\u813e\u916a\u6c28\u9178\u6fc0\u9176\uff08SYK\uff09\u9009\u62e9\u6027\u6291\u5236\u5242\uff0c\u7528\u4e8eNPM1\u7a81\u53d8\u6025\u6027\u9ad3\u7ec6\u80de\u767d\u8840\u75c5\uff08AML\uff09\u7684\u4e00\u7ebf\u6cbb\u7597\u3002\u516c\u53f8\u8fd8\u6b63\u5728\u5f00\u53d1KB-0742\u2014\u2014\u4e00\u79cd\u7ec6\u80de\u5468\u671f\u86cb\u767d\u4f9d\u8d56\u6027\u6fc0\u91769\uff08CDK9\uff09\u7684\u53e3\u670d\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597MYC\u6269\u589e\u7684\u5b9e\u4f53\u7624\u3002<\/p>\n

Kronos Bio\u603b\u90e8\u4f4d\u4e8e\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u5723\u9a6c\u7279\u5965\uff0c\u5728\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u8bbe\u6709\u7814\u7a76\u8bbe\u65bd\u3002\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1awww.kronosbio.com<\/a>\u6216\u5728LinkedIn<\/a>\u4e0a\u5173\u6ce8\u516c\u53f8\u3002<\/p>\n

\u5173\u4e8e<\/b>Invivoscribe<\/b><\/p>\n

Invivoscribe 28\u5e74\u591a\u6765\u4e00\u76f4\u4e13\u6ce8\u4e8e\u901a\u8fc7Precision Diagnostics®<\/sup>\u6539\u5584\u751f\u6d3b\uff0c\u901a\u8fc7\u4e3a160\u4e2a\u56fd\u5bb6\/\u5730\u533a\u7684700\u591a\u5bb6\u5ba2\u6237\u5f00\u53d1\u548c\u51fa\u552e\u6807\u51c6\u5316\u8bd5\u5242\u3001\u6d4b\u8bd5\u548c\u751f\u7269\u4fe1\u606f\u5b66\u5de5\u5177\uff0c\u63a8\u8fdb\u7cbe\u51c6\u533b\u5b66\u9886\u57df\u7684\u53d1\u5c55\u3002Invivoscribe\u8fd8\u4e0e\u5236\u836f\u516c\u53f8\u5408\u4f5c\uff0c\u901a\u8fc7\u652f\u6301\u56fd\u9645\u4e34\u5e8a\u8bd5\u9a8c\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u4f34\u968f\u8bca\u65ad\u3001\u63d0\u4f9b\u76d1\u7ba1\u548c\u5b9e\u9a8c\u5ba4\u670d\u52a1\u7684\u4e13\u4e1a\u77e5\u8bc6\u52a0\u901f\u65b0\u836f\u548c\u7597\u6cd5\u7684\u6279\u51c6\uff0c\u5bf9\u5168\u7403\u5065\u5eb7\u4e8b\u4e1a\u4ea7\u751f\u4e86\u91cd\u5927\u5f71\u54cd\u3002Invivoscribe\u5177\u6709\u7ecf\u8bc1\u5b9e\u7684\u80fd\u529b\uff0c\u53ef\u901a\u8fc7\u6211\u4eec\u7684\u56fd\u9645\u4e34\u5e8a\u5b9e\u9a8c\u5ba4\u5b50\u516c\u53f8\uff08LabPMM\uff09\u5728\u5168\u7403\u63d0\u4f9b\u53ef\u5206\u53d1\u8bd5\u5242\u3001\u8bd5\u5242\u76d2\u548c\u5bf9\u7167\u54c1\u53ca\u4e34\u5e8a\u8bd5\u9a8c\u670d\u52a1\uff0c\u662f\u4e00\u4e2a\u7406\u60f3\u7684\u5408\u4f5c\u4f19\u4f34\u3002\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1awww.invivoscribe.com<\/a>\u6216\u8054\u7cfbInvivoscribe\uff1acustomerservice@invivoscribe.com<\/a>\u3002<\/p>\n

\u524d\u77bb\u6027<\/b>\u9648\u8ff0<\/b><\/p>\n

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Kronos Bio<\/b>\u8054\u7cfb\u4eba\uff1a<\/b> Marni Kottle
Kronos Bio
(650) 900-3450
mkottle@kronosbio.com<\/a><\/p>\n

\u6295<\/b>\u8d44\u8005\uff1a<\/b> Claudia Styslinger
Argot Partners
(212) 600-1902
kronosbio@argotpartners.com<\/a><\/p>\n

\u5a92\u4f53\uff1a<\/b> Sheryl Seapy
Real Chemistry
(949) 903-4750
sseapy@realchemistry.com<\/a><\/p>\n

Invivoscribe<\/b>\u8054\u7cfb\u4eba\uff1a<\/b> Tony Lialin
\u9996\u5e2d\u5546\u52a1\u5b98\uff0cInvivoscribe
tlialin@invivoscribe.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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Kronos Bio\u8054\u7cfb\u4eba\uff1a Marni KottleKronos Bio(650) 900-3450mkottle@kronosbio.com \u6295\u8d44\u8005\uff1a Claudia StyslingerArgot Partners(212) 600-1902kronosbio@argotpartners.com \u5a92\u4f53\uff1a Sheryl SeapyReal Chemistry(949)… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":76260,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-76257","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/76257","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=76257"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/76257\/revisions"}],"predecessor-version":[{"id":76259,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/76257\/revisions\/76259"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/76260"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=76257"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=76257"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=76257"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}