{"id":71311,"date":"2022-07-04T06:10:00","date_gmt":"2022-07-03T23:10:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022070406100071311"},"modified":"2022-07-04T22:18:58","modified_gmt":"2022-07-04T14:18:58","slug":"%e8%85%be%e7%9b%9b%e5%8d%9a%e8%8d%af%e5%bc%95%e8%bf%9bvir-biotechnology-%e9%9d%b6%e5%90%91%e4%b9%99%e5%9e%8b%e8%82%9d%e7%82%8e%e7%9a%84%e5%b9%bf%e6%b3%9b%e4%b8%ad%e5%92%8c%e5%8d%95%e5%85%8b%e9%9a%86","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022070406100071311","title":{"rendered":"\u817e\u76db\u535a\u836f\u5f15\u8fdbVir Biotechnology \u9776\u5411\u4e59\u578b\u809d\u708e\u7684\u5e7f\u6cdb\u4e2d\u548c\u5355\u514b\u9686\u6297\u4f53VIR-3434\u5728\u5927\u4e2d\u534e\u533a\u7684\u5546\u4e1a\u6743\u76ca"},"content":{"rendered":"\n\n\n
\"\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

VIR-3434\u5728\u4e2d\u56fd\u7684\u72ec\u5bb6\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6743\u5229\u5c06\u52a0\u5f3a\u516c\u53f8\u5728\u4e59\u809d\u9886\u57df\u7684\u9886\u5bfc\u5730\u4f4d\u548c\u5f3a\u5927\u7684\u4e34\u5e8a\u7ba1\u7ebf<\/i><\/p>\n

Vir\u7684\u91cd\u8981\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u4f7f\u591a\u79cd\u8054\u5408\u6cbb\u7597\u65b9\u6848\u6210\u4e3a\u516c\u53f8\u5f00\u53d1HBV\u529f\u80fd\u6027\u6cbb\u7597\u6218\u7565\u7684\u4e00\u90e8\u5206<\/i><\/p>\n

\u5317\u4eac\u548c\u5317\u5361\u7f57\u83b1\u7eb3\u5dde\u8fbe\u52d2\u59c6\u5e02<\/span>2022\u5e747\u67084\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u817e\u76db\u535a\u836f\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8<\/a>Brii Biosciences\uff08\u4ee5\u4e0b\u7b80\u79f0"\u817e\u76db\u535a\u836f"\u6216"\u516c\u53f8"\uff0c\u80a1\u7968\u4ee3\u7801\uff1a2137.HK\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u4e8e\u9488\u5bf9\u60a3\u8005\u672a\u88ab\u6ee1\u8db3\u7684\u9700\u6c42\u4ee5\u53ca\u91cd\u5927\u516c\u5171\u536b\u751f\u6027\u75be\u75c5\u5f00\u53d1\u521b\u65b0\u7597\u6cd5\u7684\u8de8\u56fd\u4f01\u4e1a\uff0c\u4eca\u65e5\u5ba3\u5e03\uff0c\u4f5c\u4e3a\u4e0eVir Biotechnology, Inc.\uff08"Vir"\uff0c\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aVIR\uff09\u66f4\u5e7f\u6cdb\u5408\u4f5c\u7684\u4e00\u90e8\u5206\uff0c\u516c\u53f8\u884c\u4f7f\u4e86\u5176\u9009\u62e9\u6743\uff0c\u83b7\u5f97VIR-3434\u5728\u5927\u4e2d\u534e\u533a\u7684\u72ec\u5bb6\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6743\u5229\u3002\u8fd9\u4e00\u4e3e\u63aa\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86\u516c\u53f8\u9886\u5148\u7684\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u6cbb\u7597\u5019\u9009\u836f\u7269\u4e34\u5e8a\u7ba1\u7ebf\uff0c\u5e76\u4f5c\u4e3a\u516c\u53f8\u81f4\u529b\u4e8e\u5f00\u53d1HBV\u529f\u80fd\u6027\u6cbb\u6108\u7597\u6cd5\u7684\u4e00\u90e8\u5206\uff0c\u4e3a\u516c\u53f8\u63a2\u7d22\u6f5c\u5728\u7684\u8054\u5408\u7597\u6cd5\u63d0\u4f9b\u4e86\u66f4\u5e7f\u6cdb\u7684\u9009\u62e9\u3002<\/p>\n

\n<\/p><\/div>\n

VIR-3434\uff0c\u4ea6\u79f0\u4e3aBRII-877\uff0c\u662f\u4e00\u79cd\u9776\u5411HBV\u7684\u5e7f\u6cdb\u4e2d\u548c\u5355\u514b\u9686\u6297\u4f53\uff0c\u76ee\u524d\u5904\u4e8e2\u671f\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\u3002\u8fd9\u662f\u817e\u76db\u535a\u836f\u5bf9Vir\u516c\u53f8\u7684\u4f20\u67d3\u6027\u75be\u75c5\u9879\u76ee\u884c\u4f7f\u7684\u7b2c\u4e8c\u9879\u5f15\u8fdb\u9009\u62e9\u6743\uff0c\u516c\u53f8\u4ecd\u62e5\u6709\u5176\u4f59\u4e24\u9879\u5f85\u884c\u4f7f\u7684\u5f15\u8fdb\u9009\u62e9\u6743\u3002<\/p>\n

\u817e\u76db\u535a\u836f\u9996\u5e2d\u533b\u5b66\u5b98\u4e25\u7acb\u535a\u58eb\u8868\u793a\uff1a\u201c\u901a\u8fc7\u884c\u4f7f\u6211\u4eec\u5bf9VIR-3434\uff08BRII-877\uff09\u7684\u9009\u62e9\u6743\uff0c\u817e\u76db\u535a\u836f\u8fdb\u4e00\u6b65\u5de9\u56fa\u4e86\u6211\u4eec\u5728\u4e3a\u4e2d\u56fd\u6570\u5343\u4e07HBV\u60a3\u8005\u5f00\u53d1\u529f\u80fd\u6027\u6cbb\u6108\u7597\u6cd5\u7684\u9886\u5148\u5730\u4f4d\u3002Vir \u8fd1\u671f\u516c\u5e03\u7684\u6570\u636e\u663e\u793a\uff0c BRII-835\uff08VIR-2218\uff09\u548c BRII-877\uff08VIR-3434\uff09\u6709\u76f8\u4e92\u53e0\u52a0\u4f5c\u7528\uff0c\u53ef\u663e\u8457\u964d\u4f4e\u4e59\u578b\u809d\u708e\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\uff0c\u65e0\u663e\u8457\u7684\u4e34\u5e8a\u5b89\u5168\u4fe1\u53f7\u3002\u6211\u4eec\u76f8\u4fe1\uff0c\u8fd9\u4e00\u65b0\u9879\u76ee\u5c06\u8fdb\u4e00\u6b65\u52a0\u5f3a\u6211\u4eec\u7684HBV\u7ba1\u7ebf\uff0c\u4e3a\u6240\u6709\u60a3\u8005\u63d0\u4f9b\u66f4\u6709\u6548\u3001\u66f4\u6709\u4fdd\u8bc1\u7684HBsAg\u964d\u4f4e\u65b9\u6848\u3002BRII-877\uff08VIR-3434\uff09\u5c06\u878d\u5165\u5230\u6211\u4eec\u7684\u521b\u65b0\u836f\u7269\u8054\u5408\u7597\u6cd5\u7b56\u7565\u4e2d\uff0c\u4ece\u800c\u63d0\u9ad8\u5728\u6240\u6709\u60a3\u8005\u4eba\u7fa4\u7684\u529f\u80fd\u6027\u6cbb\u6108\u7387\u3002\u817e\u76db\u535a\u836f\u4e00\u76f4\u81f4\u529b\u4e8e\u63a2\u7d22\u4e00\u7cfb\u5217\u7684\u8054\u5408\u6cbb\u7597\u65b9\u6848\uff0c\u6211\u4eec\u4e0eVir \u7684\u6301\u7eed\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\uff0c\u4ee5\u53ca\u6301\u7eed\u6269\u5c55\u6211\u4eec\u5f3a\u5927HBV\u7ba1\u7ebf\u7b49\u4e3e\u63aa\uff0c\u5c06\u8fdb\u4e00\u6b65\u52a0\u5f3a\u6211\u4eec\u5bf9HBV\u60a3\u8005\u7684\u627f\u8bfa\u3002\u201d<\/p>\n

\u901a\u8fc7\u5229\u7528\u6f5c\u5728\u7684\u8054\u5408\u7597\u6cd5\u6765\u5f00\u53d1HBV\u529f\u80fd\u6027\u6cbb\u6108\u65b9\u6848\u662f\u817e\u76db\u535a\u836f\u72ec\u7279\u7684\u7b56\u7565\u3002\u516c\u53f8\u76ee\u524d\u6b63\u5728\u5f00\u5c55BRII-179\uff08VBI-2601\uff09\u548c BRII-835\uff08VIR-2218\uff09\u8054\u5408\u7597\u6cd5\uff0c\u4ee5\u53caBRII-179\u548c\/\u6216BRII-835\u4e0e\u5176\u4ed6\u836f\u7269\u8054\u5408\u7597\u6cd5\u7b49\u591a\u9879\u7814\u7a76\u3002\u817e\u76db\u535a\u836f\u7684\u5408\u4f5c\u4f19\u4f34Vir\u4e5f\u5728\u8bc4\u4f30VIR-2218\uff08BRII-835\uff09\u4e0e\u5409\u5229\u5fb7\u7684\u5728\u7814\u836f\u7269TLR-8\u6fc0\u52a8\u5242selgantolimod\uff08GS-9688\uff09\u548c\u5df2\u6279\u51c6\u7684PD-1\u6291\u5236\u5242nivolumab\u4e00\u8d77\u7528\u4e8eHBV\u6cbb\u7597\u76842\u671f\u4e34\u5e8a\u7814\u7a76\u3002\u76ee\u524d\u591a\u4e2a\u6d89\u53caBRII-835\uff08VIR-2218\uff09\uff0cBRII-877\uff08VIR-3434\uff09\u548cBRII-179\uff08VBI-2601\uff09\u7684\u8054\u5408\u7597\u6cd5\u5904\u4e8e2\u671f\u4e34\u5e8a\u7814\u7a76\u9636\u6bb5\u3002<\/p>\n

2018\u5e745\u6708\uff0c\u817e\u76db\u535a\u836f\u4e0eVir \u7b7e\u8ba2\u5408\u4f5c\u8bb8\u53ef\u6846\u67b6\u534f\u8bae\u3002\u6839\u636e\u8be5\u534f\u8bae\uff0c\u817e\u76db\u535a\u836f\u88ab\u6388\u4e88\u5f15\u8fdb\u82e5\u5e72Vir\u9879\u76ee\u5728\u5927\u4e2d\u534e\u533a\u7684\u72ec\u5bb6\u6743\u5229\u7684\u9009\u62e9\u6743\u30022020\u5e746\u6708\uff0c\u817e\u76db\u535a\u836f\u884c\u4f7f\u5176\u9009\u62e9\u6743\uff0c\u83b7\u5f97\u5728\u5927\u4e2d\u534e\u533a\u8fdb\u4e00\u6b65\u5f00\u53d1\u548c\u5546\u4e1a\u5316BRII-835\uff08VIR-2218\uff09\u7684\u72ec\u5bb6\u6743\u5229 \u3002<\/p>\n

\u6839\u636e\u534f\u8bae\u6761\u6b3e\uff0c\u5728\u884c\u4f7fVIR-3434\uff08BRII-877\uff09\u7684\u9009\u62e9\u6743\u540e\uff0c\u817e\u76db\u535a\u836f\u5c06\u652f\u4ed8\u76f8\u5173\u9009\u62e9\u6743\u884c\u4f7f\u8d39\u3001\u6ce8\u518c\u76d1\u7ba1\u548c\u5546\u4e1a\u5316\u7b49\u91cc\u7a0b\u7891\u8d39\u7528\uff0c\u4ee5\u53ca\u57fa\u4e8e\u51c0\u9500\u552e\u7684\u5206\u7ea7\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\uff0c\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u7387\u4ecb\u4e8e\u767e\u5206\u4e4b\u5341\u51e0\u5230\u767e\u5206\u4e4b\u4e8c\u5341\u51e0\u4e4b\u95f4\uff0c\u6b64\u7c7b\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u7387\u6216\u4ed8\u6b3e\u53ef\u8fdb\u884c\u82e5\u5e72\u7279\u5b9a\u6761\u4ef6\u4e0b\u7684\u51cf\u514d\u548c\u62b5\u6263\u3002<\/p>\n

\u5173\u4e8e<\/b>BRII-877\uff08VIR-3434\uff09<\/b><\/p>\n

BRII-877\uff08VIR-3434\uff09\u662f\u4e00\u79cd\u76ae\u4e0b\u6ce8\u5c04\u7684\u7814\u7a76\u6027HBV\u4e2d\u548c\u5355\u514b\u9686\u6297\u4f53\uff0c\u65e8\u5728\u963b\u65ad\u6240\u670910\u79cd\u57fa\u56e0\u578b\u7684HBV\u8fdb\u5165\u809d\u7ec6\u80de\uff0c\u5e76\u964d\u4f4e\u8840\u6db2\u4e2d\u75c5\u6bd2\u9897\u7c92\u548c\u4e9a\u75c5\u6bd2\u9897\u7c92\u7684\u6c34\u5e73\u3002BRII-877\uff08VIR-3434\uff09\u7ed3\u5408\u4e86Xencor\u7684Xtend ™\u548c\u5176\u4ed6Fc\u6280\u672f\uff0c\u901a\u8fc7\u8fd9\u4e9b\u6539\u9020\u6709\u5e0c\u671b\u5728\u611f\u67d3\u60a3\u8005\u4e2d\u4f5c\u4e3a\u9488\u5bf9HBV\u7684T\u7ec6\u80de\u75ab\u82d7\uff0c\u5e76\u5177\u6709\u5ef6\u957f\u7684\u534a\u8870\u671f\u3002<\/p>\n

\u5173<\/b>\u4e8e\u817e\u76db\u535a\u836f<\/b><\/p>\n

\u817e\u76db\u535a\u836f\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08"\u817e\u76db\u535a\u836f"\uff1b\u80a1\u4efd\u4ee3\u53f7\uff1a2137.HK\uff09\u662f\u4e00\u5bb6\u4f4d\u4e8e\u4e2d\u56fd\u53ca\u7f8e\u56fd\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u9488\u5bf9\u4e2d\u56fd\u53ca\u5168\u7403\u91cd\u5927\u611f\u67d3\u6027\u75be\u75c5\uff08\u5982\u4e59\u578b\u809d\u708e\u3001COVID-19\u3001\u4eba\u7c7b\u514d\u75ab\u7f3a\u9677\u75c5\u6bd2 (HIV) \u611f\u67d3\u3001\u591a\u91cd\u8010\u836f (MDR) \u6216\u5e7f\u6cdb\u8010\u836f\u6027 (XDR) \u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\uff09\u53ca\u5176\u5b83\u5177\u6709\u91cd\u5927\u516c\u5171\u536b\u751f\u8d1f\u62c5\u7684\u75be\u75c5\uff08\u5982\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf (CNS) \u75be\u75c5\uff09\u5f00\u53d1\u521b\u65b0\u7597\u6cd5\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95eewww.briibio.com<\/a>\u3002<\/p>\n

 <\/p>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

VIR-3434\u5728\u4e2d\u56fd\u7684\u72ec\u5bb6\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6743\u5229\u5c06\u52a0\u5f3a\u516c\u53f8\u5728\u4e59\u809d\u9886\u57df\u7684\u9886\u5bfc\u5730\u4f4d\u548c\u5f3a\u5927\u7684\u4e34\u5e8a\u7ba1\u7ebf Vir\u7684\u91cd\u8981\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u4f7f\u591a\u79cd\u8054\u5408\u6cbb\u7597\u65b9\u6848\u6210\u4e3a\u516c\u53f8\u5f00\u53d1HBV\u529f\u80fd\u6027\u6cbb\u7597\u6218\u7565\u7684\u4e00\u90e8\u5206 \u5317\u4eac\u548c\u5317\u5361\u7f57\u83b1\u7eb3\u5dde\u8fbe\u52d2\u59c6\u5e022022\u5e747\u67084\u65e5 \/\u7f8e\u901a\u793e\/ — \u817e\u76db\u535a\u836f\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8Brii 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