{"id":71114,"date":"2022-07-01T08:00:00","date_gmt":"2022-07-01T01:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022070108000071114"},"modified":"2022-07-01T22:20:09","modified_gmt":"2022-07-01T14:20:09","slug":"%e7%bb%b4%e7%ab%8b%e5%bf%97%e5%8d%9a%e4%bb%bb%e5%91%bd%e8%94%a1%e8%83%9c%e5%88%a9%e5%8d%9a%e5%a3%ab%e4%b8%ba%e9%a6%96%e5%b8%ad%e5%8c%bb%e5%ad%a6%e5%ae%98","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022070108000071114","title":{"rendered":"\u7ef4\u7acb\u5fd7\u535a\u4efb\u547d\u8521\u80dc\u5229\u535a\u58eb\u4e3a\u9996\u5e2d\u533b\u5b66\u5b98"},"content":{"rendered":"

\u5357\u4eac<\/span>2022\u5e747\u67081\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — 2022\u5e747\u67081\u65e5\uff0c\u5357\u4eac\u7ef4\u7acb\u5fd7\u535a\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0"\u7ef4\u7acb\u5fd7\u535a"\uff09\u5ba3\u5e03\u4efb\u547d\u8521\u80dc\u5229\u535a\u58eb\uff08<\/b>MD, PhD\uff09\u4e3a\u516c\u53f8\u9996\u5e2d\u533b\u5b66\u5b98\uff08CMO\uff09\uff0c\u5168\u9762\u8d1f\u8d23\u516c\u53f8\u65b0\u836f\u9879\u76ee\u5168\u7403\u4e34\u5e8a\u5f00\u53d1\u5de5\u4f5c\uff0c\u5236\u5b9a\u548c\u5b9e\u65bd\u4e34\u5e8a\u53d1\u5c55\u6218\u7565\uff0c\u53c2\u4e0e\u516c\u53f8\u6574\u4f53\u4e1a\u52a1\u548c\u53d1\u5c55\u6218\u7565\u7684\u89c4\u5212\u548c\u5b9e\u65bd\u3002<\/b>\u8521\u535a\u58eb\u76f4\u63a5\u6c47\u62a5\u7ed9\u7ef4\u7acb\u5fd7\u535a\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u3001CEO\u5eb7\u5c0f\u5f3a\u535a\u58eb\u3002<\/p>\n

\n

\"\u8521\u80dc\u5229<\/a>
\u8521\u80dc\u5229 Charles \u535a\u58eb \u7ef4\u7acb\u5fd7\u535a\u9996\u5e2d\u533b\u5b66\u5b98<\/span><\/p>\n<\/p><\/div>\n

\u8521\u535a\u58eb\u662f\u80bf\u7624\u9886\u57df\u548c\u8f6c\u5316\u533b\u5b66\u9886\u57df\u7684\u4e34\u5e8a\u79d1\u5b66\u5bb6\u3001\u5916\u79d1\u533b\u751f\uff0c\u5728\u533b\u836f\u884c\u4e1a\u6df1\u8015\u8d85\u8fc720\u5e74\uff0c\u5728\u56fd\u9645\u8457\u540d\u79d1\u7814\u673a\u6784\u548c\u5168\u7403\u9876\u5c16\u5236\u836f\u4f01\u4e1a\u7814\u53d1\u90e8\u95e8\u62e5\u6709\u4e30\u5bcc\u7684\u5de5\u4f5c\u7ecf\u5386\u3002\u6210\u529f\u5730\u5efa\u7acb\u5e76\u9886\u5bfc\u5168\u7403\u56e2\u961f\u5b8c\u6210\u4e86\u591a\u4e2a\u80bf\u7624\u9886\u57df\u7684IND\uff0cBLA\/NDA\u7533\u62a5\uff0c\u5305\u62ec\u514d\u75ab\u6cbb\u7597\u3001\u6297\u4f53\u3001\u6297\u4f53\u5076\u8054\u836f\u7269\u3001\u5c0f\u5206\u5b50\u836f\u7269\u8054\u7528\u4f8b\u5982\u5e93\u6f58\u5c3c\u897fcopanlisib\u548c\u9a6c\u5361\u66ff\u5c3ccapmatinib (INC280) \u4ee5\u53ca\u57fa\u56e0\/\u7ec6\u80de\u6cbb\u7597\u3002<\/p>\n

\u8521\u535a\u58eb\u5e08\u4ece\u5317\u4eac\u5927\u5b66\u4eba\u6c11\u533b\u9662\u9662\u957f\u3001\u4e2d\u534e\u5916\u79d1\u5b66\u4f1a\u4e3b\u4efb\u675c\u5982\u6631\u6559\u6388\uff0c\u4e8e2000\u5e74\u83b7\u5317\u4eac\u5927\u5b66\u5916\u79d1\u533b\u5b66\u535a\u58eb\u5b66\u4f4d\u3002 \u968f\u540e\u8d74\u7f8e\u5728\u5fb7\u514b\u8428\u65af\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\uff08UT MD Anderson Cancer Center\uff09\u5f00\u59cb\u535a\u58eb\u540e\u57f9\u8bad\uff0c\u5e08\u4ece\u73b0\u4efb\u8d1d\u52d2\u533b\u5b66\u9662\u7cbe\u51c6\u73af\u5883\u5065\u5eb7\u4e2d\u5fc3\u4e3b\u4efb\u3001\u7f8e\u56fd\u6bd2\u7406\u5b66\u4f1a\u524d\u4efb\u526f\u4e3b\u5e2dDr. Cheryl Walker\u3002\u8521\u535a\u58eb\u5728\u79d1\u5b66\u548c\u836f\u7269\u5f00\u53d1\u65b9\u9762\u7684\u6210\u5c31\u591a\u6b21\u83b7\u5f97\u4e86\u7f8e\u56fd\u764c\u75c7\u7814\u7a76\u534f\u4f1a\uff08AACR\uff09\u5e74\u4f1a\u5956\uff0c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u9662\u520aCozzarelli\u5956\uff0c\u548c\u62dc\u8033(Bayer)\u516c\u53f8\u6700\u4f73\u7ee9\u6548\u5956\u7b49\u5b66\u672f\u548c\u884c\u4e1a\u5956\u9879\u3002<\/p>\n

\u52a0\u5165\u7ef4\u7acb\u5fd7\u535a\u524d\uff0c\u8521\u535a\u58eb\u66fe\u4efb\u6052\u745e\uff08\u7f8e\u56fd\uff09\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u5168\u7403\u80bf\u7624\u9879\u76ee\u7684\u4e34\u5e8a\u5f00\u53d1\u3002\u5728\u6b64\u4e4b\u524d\uff0c\u8521\u535a\u58eb\u5148\u540e\u5728\u5fb7\u56fd\u62dc\u8033(Bayer)\u5168\u7403\u80bf\u7624\u4e34\u5e8a\u5f00\u53d1\u90e8\u3001\u65e5\u672c\u7b2c\u4e00\u4e09\u5171\u516c\u53f8(Daiichi-Sankyo)\u3001\u745e\u58eb\u8bfa\u534e(Novartis)\u80bf\u7624\u548c\u7f8e\u56fdIntrexon Corporation\u62c5\u4efb\u4e34\u5e8a\u7814\u53d1\u9879\u76ee\u8d1f\u8d23\u4eba\u3002<\/p>\n

\u7ef4\u7acb\u5fd7\u535a\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u3001CEO\u5eb7\u5c0f\u5f3a\u535a\u58eb\u8868\u793a\uff1a"\u6211\u4eec\u975e\u5e38\u8363\u5e78\u80fd\u591f\u9080\u8bf7\u5230\u8521\u535a\u58eb\u52a0\u76df\u7ef4\u7acb\u5fd7\u535a\uff0c\u516c\u53f8\u5168\u4f53\u5458\u5de5\u70ed\u70c8\u6b22\u8fce\u8521\u535a\u58eb\u7684\u52a0\u5165\u3002\u8521\u535a\u58eb\u5177\u6709\u4e30\u5bcc\u7684\u4e34\u5e8a\u7ecf\u9a8c\u3001\u5353\u8d8a\u7684\u79d1\u7814\u80fd\u529b\u4ee5\u53ca\u6df1\u539a\u7684\u533b\u5b66\u80cc\u666f\u3002\u7ef4\u7acb\u5fd7\u535a\u76ee\u524d\u6709<\/b>5\u4e2a\u9879\u76ee\u5728\u4e34\u5e8aI-II\u671f\uff0c\u503c\u6b64\u4e34\u5e8a\u5f00\u53d1\u7684\u5173\u952e\u9636\u6bb5\uff0c\u8521\u535a\u58eb\u7684\u52a0\u5165\u6781\u5927\u7a0b\u5ea6\u4e0a\u63d0\u9ad8\u4e86\u516c\u53f8\u4e34\u5e8a\u5f00\u53d1\u7684\u80fd\u529b\u548c\u6548\u7387\uff0c\u4e5f\u5bf9\u516c\u53f8\u7684\u65b0\u836f\u7814\u53d1\u548c\u521b\u65b0\u6218\u7565\u5b9e\u65bd\u8d77\u5230\u5173\u952e\u6027\u4f5c\u7528\u3002<\/b>\u6211\u4eec\u671f\u5f85\u4e0e\u8521\u535a\u58eb\u5171\u540c\u52aa\u529b\uff0c\u9488\u5bf9\u4e34\u5e8a\u9700\u6c42\uff0c\u63a8\u52a8\u521b\u65b0\u836f\u5c3d\u65e9\u60e0\u53ca\u60a3\u8005\uff0c\u628a\u516c\u53f8\u6253\u9020\u6210\u56fd\u9645\u4e00\u6d41\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002"<\/p>\n

\u7ef4\u7acb\u5fd7\u535a\u9996\u5e2d\u533b\u5b66\u5b98\u8521\u80dc\u5229\u535a\u58eb\u8868\u793a\uff1a"\u6211\u975e\u5e38\u9ad8\u5174\u52a0\u5165\u7ef4\u7acb\u5fd7\u535a\u62c5\u4efb\u9996\u5e2d\u533b\u5b66\u5b98\uff01\u8fd9\u5c06\u662f\u4e00\u6b21\u975e\u5e38\u6709\u8da3\u7684\u65c5\u7a0b\u3002\u7ef4\u7acb\u5fd7\u535a\u62e5\u6709\u826f\u597d\u7684\u6280\u672f\u5e73\u53f0\uff0c\u5145\u6ee1\u6d3b\u529b\u548c\u521b\u65b0\u7cbe\u795e\u3002<\/b>\u6211\u5c06\u4e0e\u6211\u7684\u540c\u9053\u4ee5\u89e3\u51b3\u80bf\u7624\u7684\u533b\u836f\u9700\u6c42\u4e3a\u4f7f\u547d\uff0c\u4ee5\u79d1\u5b66\u4e3a\u6307\u5bfc\uff0c\u4ee5\u6218\u7565\u6027\uff0c\u524d\u77bb\u6027\u548c\u521b\u65b0\u6027\u7684\u8bbe\u8ba1\u91cd\u70b9\u7a81\u7834\uff0c\u5408\u4f5c\u5f00\u53d1\uff0c\u4e3a\u4eba\u7c7b\u5065\u5eb7\u505a\u51fa\u8d21\u732e\u3002<\/b>\u6211\u671f\u5f85\u5728\u8fd9\u4e2a\u8fc7\u7a0b\u4e2d\u8fce\u63a5\u6311\u6218\uff0c\u5e76\u548c\u6211\u7684\u540c\u4e8b\u901a\u529b\u5408\u4f5c\uff0c\u5f00\u53d1\u51fa\u521b\u65b0\u7684\u6cbb\u7597\u65b9\u6848, \u4e3a\u90a3\u4e9b\u5728\u7edd\u671b\u548c\u75db\u82e6\u4e2d\u6323\u624e\u7684\u75c5\u4eba\u5e26\u6765\u751f\u7684\u5e0c\u671b\uff01"<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5357\u4eac2022\u5e747\u67081\u65e5 \/\u7f8e\u901a\u793e\/ — 2022\u5e747\u67081\u65e5\uff0c\u5357\u4eac\u7ef4\u7acb\u5fd7\u535a\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0"\u7ef4\u7acb\u5fd7\u535a"\uff09\u5ba3\u5e03\u4efb\u547d\u8521\u80dc\u5229\u535a\u58eb\uff08MD, PhD\uff09\u4e3a\u516c\u53f8\u9996\u5e2d\u533b\u5b66\u5b98\uff08CMO\uff09\uff0c\u5168\u9762\u8d1f\u8d23\u516c\u53f8\u65b0\u836f\u9879\u76ee\u5168\u7403\u4e34\u5e8a\u5f00\u53d1\u5de5\u4f5c\uff0c\u5236\u5b9a\u548c\u5b9e\u65bd\u4e34\u5e8a\u53d1\u5c55\u6218\u7565\uff0c\u53c2\u4e0e\u516c\u53f8\u6574\u4f53\u4e1a\u52a1\u548c\u53d1\u5c55\u6218\u7565\u7684\u89c4\u5212\u548c\u5b9e\u65bd\u3002\u8521\u535a\u58eb\u76f4\u63a5\u6c47\u62a5\u7ed9\u7ef4\u7acb\u5fd7\u535a\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u3001CEO\u5eb7\u5c0f\u5f3a\u535a\u58eb\u3002 \u8521\u80dc\u5229 Charles \u535a\u58eb \u7ef4\u7acb\u5fd7\u535a\u9996\u5e2d\u533b\u5b66\u5b98 \u8521\u535a\u58eb\u662f\u80bf\u7624\u9886\u57df\u548c\u8f6c\u5316\u533b\u5b66\u9886\u57df\u7684\u4e34\u5e8a\u79d1\u5b66\u5bb6\u3001\u5916\u79d1\u533b\u751f\uff0c\u5728\u533b\u836f\u884c\u4e1a\u6df1\u8015\u8d85\u8fc720\u5e74\uff0c\u5728\u56fd\u9645\u8457\u540d\u79d1\u7814\u673a\u6784\u548c\u5168\u7403\u9876\u5c16\u5236\u836f\u4f01\u4e1a\u7814\u53d1\u90e8\u95e8\u62e5\u6709\u4e30\u5bcc\u7684\u5de5\u4f5c\u7ecf\u5386\u3002\u6210\u529f\u5730\u5efa\u7acb\u5e76\u9886\u5bfc\u5168\u7403\u56e2\u961f\u5b8c\u6210\u4e86\u591a\u4e2a\u80bf\u7624\u9886\u57df\u7684IND\uff0cBLA\/NDA\u7533\u62a5\uff0c\u5305\u62ec\u514d\u75ab\u6cbb\u7597\u3001\u6297\u4f53\u3001\u6297\u4f53\u5076\u8054\u836f\u7269\u3001\u5c0f\u5206\u5b50\u836f\u7269\u8054\u7528\u4f8b\u5982\u5e93\u6f58\u5c3c\u897fcopanlisib\u548c\u9a6c\u5361\u66ff\u5c3ccapmatinib (INC280) \u4ee5\u53ca\u57fa\u56e0\/\u7ec6\u80de\u6cbb\u7597\u3002 \u8521\u535a\u58eb\u5e08\u4ece\u5317\u4eac\u5927\u5b66\u4eba\u6c11\u533b\u9662\u9662\u957f\u3001\u4e2d\u534e\u5916\u79d1\u5b66\u4f1a\u4e3b\u4efb\u675c\u5982\u6631\u6559\u6388\uff0c\u4e8e2000\u5e74\u83b7\u5317\u4eac\u5927\u5b66\u5916\u79d1\u533b\u5b66\u535a\u58eb\u5b66\u4f4d\u3002 \u968f\u540e\u8d74\u7f8e\u5728\u5fb7\u514b\u8428\u65af\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\uff08UT MD Anderson Cancer Center\uff09\u5f00\u59cb\u535a\u58eb\u540e\u57f9\u8bad\uff0c\u5e08\u4ece\u73b0\u4efb\u8d1d\u52d2\u533b\u5b66\u9662\u7cbe\u51c6\u73af\u5883\u5065\u5eb7\u4e2d\u5fc3\u4e3b\u4efb\u3001\u7f8e\u56fd\u6bd2\u7406\u5b66\u4f1a\u524d\u4efb\u526f\u4e3b\u5e2dDr. Cheryl 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Corporation\u62c5\u4efb\u4e34\u5e8a\u7814\u53d1\u9879\u76ee\u8d1f\u8d23\u4eba\u3002 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