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\u9664\u6b64\u6b21\u83b7\u6279\u4e0a\u5e02\u6240\u57fa\u4e8e\u7684CHART\u7814\u7a76\u5916\uff0c\u745e\u7ef4\u9c81\u80fa\u7684\u53e6\u4e00\u9879III\u671f\u7814\u7a76\uff0c\u5373\u745e\u7ef4\u9c81\u80fa\u56f4\u624b\u672f\u671f\u6cbb\u7597\u9ad8\u5371\u524d\u5217\u817a\u764c\u7684\u56fd\u9645\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u5bf9\u7167\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4e5f\u5df2\u4e8e2021\u5e749\u6708\u542f\u52a8\u5165\u7ec4\u3002<\/p>\n

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\u672a\u6765\u53d1\u5c55\u4e2d\uff0c\u6052\u745e\u533b\u836f\u5c06\u59cb\u7ec8\u79c9\u6301"\u79d1\u6280\u4e3a\u672c\uff0c\u4e3a\u4eba\u7c7b\u521b\u9020\u5065\u5eb7\u751f\u6d3b"\u7684\u4f7f\u547d\uff0c\u575a\u5b9a\u4e0d\u79fb\u5b9e\u65bd\u79d1\u6280\u521b\u65b0\u548c\u56fd\u9645\u5316\u53cc\u8f6e\u9a71\u52a8\u6218\u7565\uff0c\u52aa\u529b\u7814\u5236\u66f4\u591a\u65b0\u836f\u3001\u597d\u836f\uff0c\u670d\u52a1\u5065\u5eb7\u4e2d\u56fd\uff0c\u60e0\u53ca\u5e7f\u5927\u60a3\u8005\u3002<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u53c2\u8003\u6587\u732e\uff1a<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30101\u3011.   Sung H, Ferlay J, Siegel RL, et al: Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 71:209-249, 2021<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30102\u3011.   Chen W, Zheng R, Baade PD, et al: Cancer statistics in China, 2015. CA Cancer J Clin 66:115-32, 2016<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30103\u3011.   Latest global cancer data: cancer burden rises to 19.3 million new cases and 10.0 million cancer deaths in 2020\uff3bEB\/OL\uff3d, 2021<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30104\u3011.   \u674e\u661f, \u66fe\u6653\u52c7: \u4e2d\u56fd\u524d\u5217\u817a\u764c\u6d41\u884c\u75c5\u5b66\u7814\u7a76\u8fdb\u5c55. \u80bf\u7624\u9632\u6cbb\u7814\u7a76 48:98-102, 2021<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30105\u3011.   \u9a6c\u6625\u5149, \u53f6\u5b9a\u4f1f, \u674e\u957f\u5cad, et al: \u524d\u5217\u817a\u764c\u7684\u6d41\u884c\u75c5\u5b66\u7279\u5f81\u53ca\u665a\u671f\u4e00\u7ebf\u5185\u5206\u6ccc\u6cbb\u7597\u5206\u6790. \u4e2d\u534e\u5916\u79d1\u6742\u5fd7 46:921-925, 2008<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30106\u3011.   \u674e\u5c0f\u5347, \u8d75\u7389\u5170, \u9648\u4e60\u7530, et al: \u524d\u5217\u817a\u764c\u60a3\u8005\u751f\u5b57\u968f\u8bbf\u6570\u636e\u5206\u6790. \u4e2d\u56fd\u75c5\u6848 20:109-112, 2019<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30107\u3011.   \u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u6ccc\u5c3f\u7537\u751f\u6b96\u7cfb\u80bf\u7624\u4e13\u4e1a\u59d4\u5458\u4f1a: 2018\u7248\u8f6c\u79fb\u6027\u524d\u5217\u817a\u764c\u8bca\u6cbb\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6. \u4e2d\u534e\u5916\u79d1\u6742\u5fd7 56:646-652, 2018<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30108\u3011.   Surveillance E, and End Results (SEER): Program. SEER Site record[EB\/OL] Http:\/\/seer.cancer.gov\/siterecord\/icdo3_d01272003\/<\/a>. 2013<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u30109\u3011.   Dorr M, Holzel D, Schubert-Fritschle G, et al: Changes in prognostic and therapeutic parameters in prostate cancer from an epidemiological view over 20 years. Oncol Res Treat 38:8-14, 2015<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301010\u3011. \u4e2d\u56fd\u524d\u5217\u817a\u764c\u8bca\u65ad\u6cbb\u7597\u6307\u5357-2014\u5e74\u7248.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301011\u3011.  Ryan CJ, Smith MR, de Bono JS, et al: Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med 368:138-48, 2013<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301012\u3011.  Beer TM, Armstrong AJ, Rathkopf DE, et al: Enzalutamide in metastatic prostate cancer before chemotherapy. N Engl J Med 371:424-33, 2014<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301013\u3011.  Chi KN, Agarwal N, Bjartell A, et al: Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer. N Engl J Med 381:13-24, 2019<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301014\u3011.  Armstrong AJ, Szmulewitz RZ, Petrylak DP, et al: ARCHES: A Randomized, Phase III Study of Androgen Deprivation Therapy With Enzalutamide or Placebo in Men With Metastatic Hormone-Sensitive Prostate Cancer. J Clin Oncol 37:2974-2986, 2019<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301015\u3011.  Fizazi K, Tran N, Fein L, et al: Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer. N Engl J Med 377:352-360, 2017<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301016\u3011.  Qin X, Ji D, Gu W, Han W, et al: Activity and safety of SHR3680, a novel antiandrogen, in patients with metastatic castration-resistant prostate cancer: a phase I\/II trial. BMC Med 20:84-, 2022<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u301017\u3011.  Ye DW, Gu W, Han W, et al: A phase 3 trial of SHR3680 versus bicalutamide in combination with androgen deprivation therapy (ADT) in patients with high-volume metastatic hormone-sensitive prostate cancer (mHSPC). J Clin Oncol 40(suppl 16; abstr 5005), 2022<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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