{"id":70805,"date":"2022-06-28T07:00:00","date_gmt":"2022-06-28T00:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022062807000070805"},"modified":"2022-06-28T22:16:16","modified_gmt":"2022-06-28T14:16:16","slug":"%e5%88%9b%e8%83%9c%e9%9b%86%e5%9b%a2%e8%8e%b7%e9%80%89%e4%ba%8e2022%e5%b9%b4%e5%9b%bd%e9%99%85%e8%82%be%e8%84%8f%e7%97%85%e5%ad%a6%e4%bc%9a%e8%a1%a5%e4%bd%93%e7%9b%b8%e5%85%b3%e8%82%be%e7%97%85","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022062807000070805","title":{"rendered":"\u521b\u80dc\u96c6\u56e2\u83b7\u9009\u4e8e2022\u5e74\u56fd\u9645\u80be\u810f\u75c5\u5b66\u4f1a\u8865\u4f53\u76f8\u5173\u80be\u75c5\u524d\u6cbf\u4f1a\u8bae\u4e0a\u5c55\u793aTST004\u4e34\u5e8a\u524d\u6570\u636e"},"content":{"rendered":"<p><p><span class=\"legendSpanClass\">\u82cf\u5dde<\/span><span class=\"legendSpanClass\">2022\u5e746\u670828\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u521b\u80dc\u96c6\u56e2\uff0806628.HK\uff09\uff0c\u4e00\u5bb6\u5177\u5907\u751f\u7269\u836f\u54c1\u53d1\u73b0\u3001\u7814\u53d1\u3001\u5de5\u827a\u5f00\u53d1\u548c\u751f\u4ea7\u5168\u6d41\u7a0b\u6574\u5408\u80fd\u529b\u7684\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u5e03\u5176\u83b7\u9009\u4e8e\u610f\u5927\u5229\u8d1d\u52a0\u83ab\u4e3e\u884c\u76842022\u5e74\u56fd\u9645\u80be\u810f\u75c5\u5b66\u4f1a\u8865\u4f53\u76f8\u5173\u80be\u75c5\u524d\u6cbf\u4f1a\u8bae\u4e0a\u5c55\u793aTST004\u4e34\u5e8a\u524d\u6570\u636e\u3002<\/p>\n<p>TST004\u662f\u4e00\u79cd\u9776\u5411\u7518\u9732\u805a\u7cd6\u7ed3\u5408\u51dd\u96c6\u7d20\u5173\u8054\u4e1d\u6c28\u9178\u86cb\u767d\u91762 (MASP2) \u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u88ab\u8bbe\u8ba1\u4e3a\u53ef\u9632\u6b62\u7531\u51dd\u96c6\u7d20\u901a\u8def\u8865\u4f53\u6fc0\u6d3b\u4ecb\u5bfc\u7684\u708e\u75c7\u53ca\u7ec4\u7ec7\u635f\u4f24\u3002<span id=\"spanHghlt4123\">MASP2<\/span>\u662f\u8865\u4f53\u6fc0\u6d3b\u51dd\u96c6\u7d20\u901a\u8def\u542f\u52a8\u7684\u4e00\u79cd\u5173\u952e\u9176\u3002<span id=\"spanHghlt140a\">\u7814\u7a76\u663e\u793a\uff0c\u51dd\u96c6\u7d20\u901a\u8def\u6fc0\u6d3b\u4fc3\u8fdb\u591a\u79cd\u4eba\u7c7b\u75be\u75c5\u7684\u53d1\u751f\uff0c\u5982\u514d\u75ab\u7403\u86cb\u767dA \u578b\u80be\u75c5(IgAN)\u3001\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u76f8\u5173\u8840\u6813\u6027\u5fae\u8840\u7ba1\u75c5(HSCT-TMA)\u3002<\/span>\u56e0\u6b64\uff0c\u6291\u5236MASP2\u53ef\u80fd\u662f\u4e0e\u51dd\u96c6\u7d20\u901a\u8def\u6fc0\u6d3b\u76f8\u5173\u7684\u75be\u75c5\u7684\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<p>\u94b1\u96ea\u660e\u535a\u58eb\u5728\u6c47\u62a5\u4e2d\u5f3a\u8c03\u4ee5\u4e0b\u4e34\u5e8a\u524d\u6570\u636e\uff1a<\/p>\n<ul type=\"disc\">\n<li><span id=\"spanHghltfa6a\">TST004\u4ee5\u9ad8\u4eb2\u548c\u529b\u7684\u65b9\u5f0f\u9009\u62e9\u6027\u5730\u4e0eMASP2\u7ed3\u5408\u3002&nbsp;<br \/><\/span><\/li>\n<li><span id=\"spanHghlt426a\">TST004\u663e\u793a\u51fa\u6bd4\u540c\u9776\u5728\u7814\u836f\u7269\u66f4\u5f3a\u7684\u963b\u65adMASP2\u4f9d\u8d56\u6027\u6fc0\u6d3b\u51dd\u96c6\u7d20\u8865\u4f53\u901a\u8def\u7684\u4f53\u5916\u53ca\u4f53\u5185\u6d3b\u6027\u3002<br \/><\/span><\/li>\n<li><span id=\"spanHghltce2e\">TST004\u5728\u98df\u87f9\u7334PK\/PD\u7814\u7a76\u4e2d\u663e\u793a\u51fa\u6bd4\u540c\u9776\u5728\u7814\u836f\u7269\u66f4\u6301\u4e45\u7684\u9776\u70b9\u6291\u5236\u3002<\/span><\/li>\n<li>TST004\u5728\u76ae\u4e0b\u6ce8\u5c04\u540e\u7684\u5355\u6b21\u53ca\u591a\u6b21\u5242\u91cf\u6bd2\u6027\u7814\u7a76\u4e2d\u5728\u975e\u4eba\u7c7b\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\u663e\u793a\u51fa\u5353\u8d8a\u7684\u8010\u53d7\u6027\u53ca\u5b89\u5168\u6027\u3002<\/li>\n<\/ul>\n<p>TST004\u5c06\u4ee5\u76ae\u4e0b\u6ce8\u5c04\u7ed9\u836f\uff0c<span id=\"spanHghlte20e\">\u4e0e\u540c\u9776\u5728\u7814\u6297\u4f53\u836f\u7269\u6240\u4f7f\u7528\u7684\u9759\u8109\u8f93\u6db2\u65b9\u5f0f\u76f8\u6bd4\uff0c<\/span>\u5c55\u73b0\u51fa\u663e\u8457\u4f18\u52bf\u3002<\/p>\n<p>\u201c\u514d\u75ab\u7403\u86cb\u767dA\u578b\u80be\u75c5 (IgAN) \u662f\u5168\u7403\u9ad8\u53d1\u6027\u75be\u75c5\uff0c\u4e5f\u662f\u533b\u7597\u9700\u6c42\u7f3a\u53e3\u5de8\u5927\u7684\u9886\u57df\u3002\u4e34\u5e8a\u524d\u6570\u636e\u4e3aTST004\u8fdb\u4e00\u6b65\u8bc4\u4f30\u4e3a\u8865\u4f53\u4f9d\u8d56\u6027\u75be\u75c5\uff0c\u5982\u514d\u75ab\u7403\u86cb\u767dA\u578b\u80be\u75c5(IgAN)\u53ca\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u76f8\u5173\u8840\u6813\u6027\u5fae\u8840\u7ba1\u75c5(HSCT-TMA)\u7684\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5\u63d0\u4f9b\u4e86\u4ee4\u4eba\u4fe1\u670d\u7684\u79d1\u5b66\u539f\u7406\u201d\uff0c\u521b\u80dc\u96c6\u56e2\u9996\u5e2d\u6267\u884c\u5b98\u94b1\u96ea\u660e\u535a\u58eb\u8868\u793a\uff0c\u201c\u6211\u4eec\u6b63\u5728\u52aa\u529b\u5c06TST004\u63a8\u8fdb\u81f3\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\uff0c\u5e0c\u671b\u80fd\u591f\u60e0\u53ca\u66f4\u591a\u53d7\u6025\u5207\u533b\u7597\u9700\u6c42\u7f3a\u53e3\u5f71\u54cd\u7684\u60a3\u8005\u3002\u201d<\/p>\n<p><b>\u5173\u4e8eTST004<\/b><\/p>\n<p>TST004\u662f\u4e00\u79cd\u9776\u5411\u7518\u9732\u805a\u7cd6\u7ed3\u5408\u51dd\u96c6\u7d20\u5173\u8054\u4e1d\u6c28\u9178\u86cb\u767d\u91762 (MASP2)\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u88ab\u8bbe\u8ba1\u4e3a\u53ef\u9632\u6b62\u7531\u51dd\u96c6\u7d20\u901a\u8def\u8865\u4f53\u4ecb\u5bfc\u7684\u708e\u75c7\u3002TST004\u7531\u672c\u516c\u53f8\u81ea\u4e3b\u53d1\u73b0\u53ca\u5f00\u53d1\uff0c\u5c06\u7528\u4e8e\u6cbb\u7597\u514d\u75ab\u7403\u86cb\u767dA\u578b\u80be\u75c5\uff08IgAN\uff09(\u4e00\u79cd\u9ad8\u53d1\u6027\u6162\u6027\u80be\u75c5\uff0c\u5176\u6cbb\u7597\u9009\u62e9\u975e\u5e38\u6709\u9650\uff09\u3002TST004\u4ea6\u6709\u6cbb\u7597\u591a\u79cd\u5176\u4ed6\u9002\u5e94\u75c7\u7684\u6f5c\u529b\uff0c\u5982\u8840\u6813\u6027\u5fae\u8840\u7ba1\u75c5 (TMA)\uff0c\u5e02\u573a\u6f5c\u529b\u5de8\u5927\u3002<\/p>\n<p><b>\u5173\u4e8e\u521b\u80dc\u96c6\u56e2<\/b><\/p>\n<p>\u521b\u80dc\u96c6\u56e2\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\u7684\u5728\u751f\u7269\u836f\u53d1\u73b0\u3001\u7814\u53d1\u3001\u5de5\u827a\u5f00\u53d1\u548c\u751f\u4ea7\u65b9\u9762\u5177\u6709\u5168\u9762\u7efc\u5408\u80fd\u529b\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002<\/p>\n<p>\u521b\u80dc\u96c6\u56e2\u603b\u90e8\u4f4d\u4e8e\u82cf\u5dde\uff0c\u5df2\u6210\u529f\u642d\u5efa\u4e86\u5168\u7403\u7684\u4e1a\u52a1\u5e03\u5c40\uff1a\u5728\u82cf\u5dde\u8bbe\u6709\u836f\u7269\u53d1\u73b0\u3001\u4e34\u5e8a\u548c\u8f6c\u5316\u7814\u7a76\u4e2d\u5fc3\uff0c\u521b\u80dc\u96c6\u56e2\u603b\u90e8\u53ca\u4ee5\u8fde\u7eed\u704c\u6d41\u751f\u4ea7\u5de5\u827a\u4e3a\u6838\u5fc3\u6280\u672f\u7684\u751f\u4ea7\u57fa\u5730\u4e5f\u6b63\u5728\u5efa\u8bbe\u4e2d\u3002\u5728\u676d\u5dde\u62e5\u6709\u5de5\u827a\u4e0e\u4ea7\u54c1\u5f00\u53d1\u4e2d\u5fc3\u4ee5\u53ca\u836f\u7269\u751f\u4ea7\u57fa\u5730\uff0c\u5728\u5317\u4eac\u3001\u4e0a\u6d77\u3001\u5e7f\u5dde\u548c\u7f8e\u56fd\u666e\u6797\u65af\u987f\u5206\u522b\u8bbe\u6709\u4e34\u5e8a\u5f00\u53d1\u4e2d\u5fc3\uff0c\u5e76\u5728\u7f8e\u56fd\u6ce2\u58eb\u987f\u3001\u6d1b\u6749\u77f6\u8bbe\u7acb\u4e86\u5bf9\u5916\u5408\u4f5c\u4e2d\u5fc3\u3002\u521b\u80dc\u96c6\u56e2\u7684\u5f00\u53d1\u7ba1\u7ebf\u5df2\u6709\u5341\u4e2a\u6cbb\u7597\u7528\u6297\u4f53\u65b0\u836f\u5206\u5b50\uff0c\u6db5\u76d6\u80bf\u7624\u3001\u9aa8\u79d1\u548c\u80be\u75c5\u7b49\u9886\u57df\u3002<\/p>\n<p>\u5982\u9700\u4e86\u89e3\u5173\u4e8e\u521b\u80dc\u96c6\u56e2\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a<a href=\"https:\/\/www.transcenta.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.transcenta.com<\/a>\u6216\u9886\u82f1\u8d26\u53f7\uff1aTranscenta\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u4f1a\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u3002\u8fd9\u4e9b\u8868\u8ff0\u672c\u8d28\u4e0a\u5177\u6709\u76f8\u5f53\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u3002\u5728\u4f7f\u7528\u201c\u9884\u671f\u201d\u3001\u201c\u76f8\u4fe1\u201d\u3001\u201c\u9884\u6d4b\u201d\u3001\u201c\u671f\u671b\u201d\u3001\u201c\u6253\u7b97\u201d\u53ca\u5176\u4ed6\u7c7b\u4f3c\u8bcd\u8bed\u8fdb\u884c\u8868\u8ff0\u65f6\uff0c\u51e1\u4e0e\u672c\u516c\u53f8\u6709\u5173\u7684\uff0c\u76ee\u7684\u5747\u662f\u8981\u6307\u660e\u5176\u5c5e\u524d\u77bb\u6027\u8868\u8ff0\u3002\u672c\u516c\u53f8\u5e76\u65e0\u4e49\u52a1\u4e0d\u65ad\u5730\u66f4\u65b0\u8fd9\u4e9b\u9884\u6d4b\u6027\u9648\u8ff0\u3002<\/p>\n<p>\u8fd9\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u4e43\u57fa\u4e8e\u672c\u516c\u53f8\u7ba1\u7406\u5c42\u5728\u505a\u51fa\u8868\u8ff0\u65f6\u5bf9\u672a\u6765\u4e8b\u52a1\u7684\u73b0\u6709\u770b\u6cd5\u3001\u5047\u8bbe\u3001\u671f\u671b\u3001\u4f30\u8ba1\u3001\u9884\u6d4b\u548c\u7406\u89e3\u3002\u8fd9\u4e9b\u8868\u8ff0\u5e76\u975e\u5bf9\u672a\u6765\u53d1\u5c55\u7684\u4fdd\u8bc1\uff0c\u4f1a\u53d7\u5230\u98ce\u9669\u3001\u4e0d\u786e\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u8303\u56f4\uff0c\u96be\u4ee5\u9884\u8ba1\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u4eec\u7684\u4e1a\u52a1\u3001\u7ade\u4e89\u73af\u5883\u3001\u653f\u6cbb\u3001\u7ecf\u6d4e\u3001\u6cd5\u5f8b\u548c\u793e\u4f1a\u60c5\u51b5\u7684\u672a\u6765\u53d8\u5316\u53ca\u53d1\u5c55\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4f1a\u4e0e\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8d44\u6599\u6709\u8f83\u5927\u5dee\u522b\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u82cf\u5dde2022\u5e746\u670828\u65e5 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