{"id":70214,"date":"2022-06-22T09:59:00","date_gmt":"2022-06-22T02:59:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022062209590070214"},"modified":"2022-06-22T22:51:56","modified_gmt":"2022-06-22T14:51:56","slug":"%e8%af%ba%e8%af%9a%e5%81%a5%e5%8d%8e%e8%87%aa%e4%b8%bb%e7%a0%94%e5%8f%91%e7%9a%84%e6%96%b0%e5%9e%8bshp2%e5%8f%98%e6%9e%84%e6%8a%91%e5%88%b6%e5%89%82icp-189%e5%ae%8c%e6%88%90%e9%a6%96%e4%be%8b%e6%82%a3","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022062209590070214","title":{"rendered":"\u8bfa\u8bda\u5065\u534e\u81ea\u4e3b\u7814\u53d1\u7684\u65b0\u578bSHP2\u53d8\u6784\u6291\u5236\u5242ICP-189\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f"},"content":{"rendered":"<p><p><span class=\"legendSpanClass\">\u5317\u4eac<\/span><span class=\"legendSpanClass\">2022\u5e746\u670822\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u751f\u7269\u533b\u836f\u9ad8\u79d1\u6280\u516c\u53f8\u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u65b0\u578b\u86cb\u767d\u916a\u6c28\u9178\u78f7\u9178\u9176SHP2\uff08Src Homology 2 domain containing protein tyrosine phosphatase\uff09\u53d8\u6784\u6291\u5236\u5242ICP-189\u5728\u4e2d\u56fd\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/p>\n<p>ICP-189\u662f\u4e3a\u4e86\u6cbb\u7597\u5b9e\u4f53\u80bf\u7624\u800c\u5f00\u53d1\u7684\u4e00\u79cd\u9ad8\u9009\u62e9\u6027\u7684\u53e3\u670dSHP2\u53d8\u6784\u6291\u5236\u5242\uff0c\u53ef\u7528\u4f5c\u5355\u836f\u7597\u6cd5\u53ca\/\u6216\u548c\u5176\u4ed6\u6297\u80bf\u7624\u836f\u7684\u8054\u5408\u7597\u6cd5\uff0c\u65e8\u5728\u4e3a\u80ba\u764c\u3001\u5934\u9888\u764c\u53ca\u6d88\u5316\u9053\u80bf\u7624\u7b49\u5b9e\u4f53\u7624\u63d0\u4f9b\u65b0\u7684\u4e34\u5e8a\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<p>SHP2\u5728MAPK\u4fe1\u53f7\u901a\u8def\u548c\u514d\u75ab\u68c0\u67e5\u70b9\u901a\u8def\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u53ef\u8c03\u8282\u7ec6\u80de\u589e\u6b96\u548c\u5b58\u6d3b\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793aICP-189\u5bf9\u5176\u4ed6\u78f7\u9178\u9176\u5177\u6709\u5f88\u597d\u7684\u9009\u62e9\u6027\u3002\u5728\u4f53\u5185\u529f\u6548\u7814\u7a76\u4e2d\uff0cICP-189\u5728\u5404\u79cd\u5f02\u79cd\u79fb\u690d\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u663e\u8457\u7684\u6297\u80bf\u7624\u4f5c\u7528\u3002<\/p>\n<p>\u8bfa\u8bda\u5065\u534e\u8054\u5408\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517cCEO\u5d14\u9701\u677e\u535a\u58eb\u8bf4\uff1a&quot;ICP-189\u5728\u4e2d\u7f8e\u4e24\u5730\u5747\u83b7\u6279\u4e34\u5e8a\u3002SHP2\u5df2\u6210\u4e3a\u5b9e\u4f53\u7624\u9886\u57df\u7684\u6f5c\u529b\u9776\u6807\uff0c\u6211\u4eec\u5c06\u5168\u529b\u52a0\u901f\u63a8\u8fdbICP-189\u4e34\u5e8a\u5f00\u53d1\uff0c\u5e0c\u671b\u80fd\u65e9\u65e5\u4e3a\u4e2d\u56fd\u53ca\u5168\u7403\u5b9e\u4f53\u7624\u60a3\u8005\u63d0\u4f9b\u5177\u6709\u7ade\u4e89\u529b\u7684\u6cbb\u7597\u89e3\u51b3\u65b9\u6848\u3002&quot;<\/p>\n<p><b>\u5173\u4e8e\u8bfa\u8bda\u5065\u534e<\/b><\/p>\n<p>\u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u662f\u4e00\u5bb6\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u751f\u7269\u533b\u836f\u9ad8\u79d1\u6280\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u6cbb\u7597\u9886\u57df\u7684\u4e00\u7c7b\u65b0\u836f\u7814\u5236\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u8840\u6db2\u7624\u3001\u5b9e\u4f53\u7624\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u73b0\u6709\u591a\u4e2a\u65b0\u836f\u4ea7\u54c1\u5904\u4e8e\u5546\u4e1a\u5316\u3001\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u7814\u53d1\u9636\u6bb5\u3002\u516c\u53f8\u5728\u5317\u4eac\u3001\u5357\u4eac\u3001\u4e0a\u6d77\u3001\u5e7f\u5dde\u3001\u9999\u6e2f\u4ee5\u53ca\u7f8e\u56fd\u8bbe\u6709\u5206\u652f\u673a\u6784\u3002<\/p>\n<p><b>\u8054\u7cfb\u4eba<br \/><\/b><b>\u5a92\u4f53<\/b>&nbsp;<br \/>\u9646\u6625\u534e&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<br \/>86-10-66609879&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<br \/><a href=\"mailto:chunhua.lu@innocarepharma.com\" target=\"_blank\" rel=\"nofollow noopener\">chunhua.lu@innocarepharma.com<\/a> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n<p><b>\u6295\u8d44\u8005<br \/><\/b>86-10-66609999&nbsp;<br \/><a href=\"mailto:ir@innocarepharma.com\" target=\"_blank\" rel=\"nofollow noopener\">ir@innocarepharma.com<\/a>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5317\u4eac2022\u5e746\u670822\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u751f\u7269\u533b\u836f\u9ad8\u79d1\u6280\u516c\u53f8\u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u65b0\u578b\u86cb\u767d\u916a\u6c28\u9178\u78f7\u9178\u9176SHP2\uff08Src Homology 2 domain containing protein tyrosine phosphatase\uff09\u53d8\u6784\u6291\u5236\u5242ICP-189\u5728\u4e2d\u56fd\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002 ICP-189\u662f\u4e3a\u4e86\u6cbb\u7597\u5b9e\u4f53\u80bf\u7624\u800c\u5f00\u53d1\u7684\u4e00\u79cd\u9ad8\u9009\u62e9\u6027\u7684\u53e3\u670dSHP2\u53d8\u6784\u6291\u5236\u5242\uff0c\u53ef\u7528\u4f5c\u5355\u836f\u7597\u6cd5\u53ca\/\u6216\u548c\u5176\u4ed6\u6297\u80bf\u7624\u836f\u7684\u8054\u5408\u7597\u6cd5\uff0c\u65e8\u5728\u4e3a\u80ba\u764c\u3001\u5934\u9888\u764c\u53ca\u6d88\u5316\u9053\u80bf\u7624\u7b49\u5b9e\u4f53\u7624\u63d0\u4f9b\u65b0\u7684\u4e34\u5e8a\u6cbb\u7597\u65b9\u6cd5\u3002 SHP2\u5728MAPK\u4fe1\u53f7\u901a\u8def\u548c\u514d\u75ab\u68c0\u67e5\u70b9\u901a\u8def\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u53ef\u8c03\u8282\u7ec6\u80de\u589e\u6b96\u548c\u5b58\u6d3b\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793aICP-189\u5bf9\u5176\u4ed6\u78f7\u9178\u9176\u5177\u6709\u5f88\u597d\u7684\u9009\u62e9\u6027\u3002\u5728\u4f53\u5185\u529f\u6548\u7814\u7a76\u4e2d\uff0cICP-189\u5728\u5404\u79cd\u5f02\u79cd\u79fb\u690d\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u663e\u8457\u7684\u6297\u80bf\u7624\u4f5c\u7528\u3002 \u8bfa\u8bda\u5065\u534e\u8054\u5408\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517cCEO\u5d14\u9701\u677e\u535a\u58eb\u8bf4\uff1a&quot;ICP-189\u5728\u4e2d\u7f8e\u4e24\u5730\u5747\u83b7\u6279\u4e34\u5e8a\u3002SHP2\u5df2\u6210\u4e3a\u5b9e\u4f53\u7624\u9886\u57df\u7684\u6f5c\u529b\u9776\u6807\uff0c\u6211\u4eec\u5c06\u5168\u529b\u52a0\u901f\u63a8\u8fdbICP-189\u4e34\u5e8a\u5f00\u53d1\uff0c\u5e0c\u671b\u80fd\u65e9\u65e5\u4e3a\u4e2d\u56fd\u53ca\u5168\u7403\u5b9e\u4f53\u7624\u60a3\u8005\u63d0\u4f9b\u5177\u6709\u7ade\u4e89\u529b\u7684\u6cbb\u7597\u89e3\u51b3\u65b9\u6848\u3002&quot; \u5173\u4e8e\u8bfa\u8bda\u5065\u534e \u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u662f\u4e00\u5bb6\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u751f\u7269\u533b\u836f\u9ad8\u79d1\u6280\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u6cbb\u7597\u9886\u57df\u7684\u4e00\u7c7b\u65b0\u836f\u7814\u5236\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u8840\u6db2\u7624\u3001\u5b9e\u4f53\u7624\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u73b0\u6709\u591a\u4e2a\u65b0\u836f\u4ea7\u54c1\u5904\u4e8e\u5546\u4e1a\u5316\u3001\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u7814\u53d1\u9636\u6bb5\u3002\u516c\u53f8\u5728\u5317\u4eac\u3001\u5357\u4eac\u3001\u4e0a\u6d77\u3001\u5e7f\u5dde\u3001\u9999\u6e2f\u4ee5\u53ca\u7f8e\u56fd\u8bbe\u6709\u5206\u652f\u673a\u6784\u3002 \u8054\u7cfb\u4eba\u5a92\u4f53&nbsp;\u9646\u6625\u534e&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;86-10-66609879&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;chunhua.lu@innocarepharma.com &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u6295\u8d44\u800586-10-66609999&nbsp;ir@innocarepharma.com&nbsp;&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2022062209590070214\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":8278,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-70214","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/70214","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=70214"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/70214\/revisions"}],"predecessor-version":[{"id":70215,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/70214\/revisions\/70215"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/8278"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=70214"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=70214"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=70214"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}