{"id":66872,"date":"2022-04-06T07:00:00","date_gmt":"2022-04-06T00:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022040607000066872"},"modified":"2022-04-06T18:10:13","modified_gmt":"2022-04-06T10:10:13","slug":"%e4%ba%91%e9%a1%b6%e6%96%b0%e8%80%80%e5%ae%a3%e5%b8%83%e4%b8%ad%e5%9b%bd%e4%ba%ba%e7%be%a4%e4%ba%9a%e7%bb%84%e7%9a%84%e4%b8%bb%e8%a6%81%e7%bb%93%e6%9e%9c%e4%b8%8enefecon%e5%85%a8%e7%90%833%e6%9c%9fnef","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022040607000066872","title":{"rendered":"\u4e91\u9876\u65b0\u8000\u5ba3\u5e03\u4e2d\u56fd\u4eba\u7fa4\u4e9a\u7ec4\u7684\u4e3b\u8981\u7ed3\u679c\u4e0eNEFECON\u5168\u74033\u671fNefIgArd\u7814\u7a76A\u90e8\u5206\u7684\u5206\u6790\u7ed3\u679c\u4e00\u81f4"},"content":{"rendered":"<p><p><span>\u4e0a\u6d77<\/span><span>2022\u5e744\u67086\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u4e91\u9876\u65b0\u8000(HKEX 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AB\u7b7e\u8ba2\u4e86\u72ec\u5bb6\u6388\u6743\u8bb8\u53ef\u534f\u8bae\uff0c\u83b7\u5f97\u4e86\u5728\u5927\u4e2d\u534e\u533a\u548c\u65b0\u52a0\u5761\u5f00\u53d1\u4ee5\u53ca\u5546\u4e1a\u5316NEFECON\u7528\u4e8e\u6cbb\u7597\u539f\u53d1\u6027IgA\u80be\u75c5\uff08IgAN\uff09\u7684\u6388\u6743\uff0c\u8be5\u534f\u8bae\u4e8e\u4eca\u5e743\u6708\u4efd\u6269\u5c55\uff0c\u5c06\u97e9\u56fd\u7eb3\u5165\u4e91\u9876\u65b0\u8000\u7684\u6388\u6743\u8bb8\u53ef\u533a\u57df\u3002<\/p>\n<p>\u4e91\u9876\u65b0\u8000\u5185\u79d1\u9886\u57df\u9996\u5e2d\u533b\u5b66\u5b98\u6731\u6b63\u7f28\u535a\u58eb\u8868\u793a\uff1a\u201c\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u770b\u5230NefIgArd\u7814\u7a76\u4e2d\uff0c\u4e2d\u56fd\u4eba\u7fa4\u4e9a\u7ec4\u4e2d\u7684\u6570\u636e\u4e0e\u5168\u7403\u7814\u7a76A\u90e8\u5206\u7684\u7ed3\u679c\u4e00\u81f4\uff0c\u8fd9\u4e9b\u6570\u636e\u5c06\u88ab\u7eb3\u5165\u4e2d\u56fd\u4e0a\u5e02\u7533\u8bf7\u7684\u9012\u4ea4\u8d44\u6599\uff0c\u8ba1\u5212\u5728\u4eca\u5e74\u4e0b\u534a\u5e74\u5b8c\u6210\u9012\u4ea4\u3002\u6211\u4eec\u5e0c\u671b\u80fd\u5c3d\u5feb\u5c06\u8fd9\u4e00\u521b\u65b0\u7597\u6cd5\u5e26\u7ed9\u5728\u4e2d\u56fd\u548c\u5176\u4ed6\u56fd\u5bb6\u5730\u533a\u7684IgA\u80be\u75c5\u60a3\u8005\u3002\u201d<\/p>\n<p>2020\u5e7411\u6708\uff0cCalliditas\u53d1\u5e03\u4e86\u5173\u952e\u6027\u5168\u74033\u671f\u7814\u7a76NefIgArd A\u90e8\u5206\u7684\u4e3b\u8981\u7ed3\u679c\uff0c\u60a3\u8005\u5728\u63a5\u53d7\u6cbb\u7597<span id=\"spanHghlt1d29\">9\u4e2a\u6708<\/span>\u540e\uff0c\u86cb\u767d\u5c3f\u4e0b\u964d\u8fbe\u5230\u4e86\u7edf\u8ba1\u5b66\u663e\u8457\u610f\u4e49\u3002 \u8be5\u7814\u7a76\u5206\u6790\u8fd8\u8fbe\u5230\u4e86\u5173\u952e\u7684\u6b21\u8981\u7ec8\u70b9\uff0c\u5373\u6cbb\u75979\u4e2a\u6708\u540e\uff0c\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0c\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u7684\u7ec4\u95f4\u5dee\u5f02\u8fbe\u5230\u4e86\u7edf\u8ba1\u5b66\u663e\u8457\u610f\u4e49\u3002Nefecon\u7684\u8010\u53d7\u6027\u826f\u597d\u3002<\/p>\n<p><b>\u5173\u4e8e<\/b><b>NEFECON<\/b><\/p>\n<p>NEFECON\u662f\u53e3\u670d\u9776\u5411\u5e03\u5730\u5948\u5fb7\u8fdf\u91ca\u80f6\u56ca\uff0c\u6210\u4e3a\u76ee\u524d\u5168\u7403\u9996\u4e2aIgA\u80be\u75c5\u7684\u9776\u5411\u6cbb\u7597\u836f\u7269\uff0c\u7528\u4e8e\u5177\u6709\u8fdb\u5c55\u98ce\u9669\u7684\u6210\u4eba\u539f\u53d1\u6027IgA\u80be\u75c5\uff0c\u964d\u4f4e\u86cb\u767d\u5c3f\u6c34\u5e73\u3002NEFECON\u662f\u5e03\u5730\u5948\u5fb7\u7684\u521b\u65b0\u53e3\u670d\u9776\u5411\u8fdf\u91ca\u5236\u5242\uff0c\u800c\u5e03\u5730\u5948\u5fb7\u662f\u4e00\u79cd\u5177\u6709\u5f3a\u7cd6\u76ae\u8d28\u6fc0\u7d20\u6d3b\u6027\u548c\u5f31\u76d0\u76ae\u8d28\u6fc0\u7d20\u6d3b\u6027\u7684\u76ae\u8d28\u7c7b\u56fa\u9187\uff0c\u9996\u8fc7\u4ee3\u8c22\u7a0b\u5ea6\u6781\u9ad8\u3002NEFECON\u4e13\u4e3aIgA\u80be\u75c5\u60a3\u8005\u7814\u5236\uff0c\u6bcf\u7c92\u8fdf\u91ca\u80f6\u56ca\u542b\u5e03\u5730\u5948\u5fb74mg\uff0c\u8986\u4ee5\u80a0\u6eb6\u5305\u8863\uff0c\u4f7f\u5f97\u836f\u7269\u53ef\u4ee5\u5b8c\u6574\u65e0\u635f\u5230\u8fbe\u56de\u80a0\u540e\u91ca\u653e\u30022019\u5e746\u6708\uff0c\u4e91\u9876\u65b0\u8000\u4e0eCalliditas\u7b7e\u8ba2\u72ec\u5bb6\u6388\u6743\u8bb8\u53ef\u534f\u8bae\uff0c\u83b7\u5f97\u5728\u5927\u4e2d\u534e\u5730\u533a\u548c\u65b0\u52a0\u5761\u5f00\u53d1\u4ee5\u53ca\u5546\u4e1a\u5316NEFECON\u7684\u6743\u5229\u3002\u8be5\u534f\u8bae\u4e8e2022\u5e743\u6708\u6269\u5c55\uff0c\u5c06\u97e9\u56fd\u7eb3\u5165\u4e91\u9876\u65b0\u8000\u7684\u8bb8\u53ef\u8303\u56f4\u3002<\/p>\n<p><b>\u5173\u4e8e<\/b><b>NeflgArd<\/b><b>\u7814\u7a76<\/b><\/p>\n<p>NeflgArd\u662f\u4e00\u9879\u6b63\u5728\u8fdb\u884c\u76843\u671f\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8bc4\u4f30\uff0c\u5728\u539f\u53d1\u6027IgA\u80be\u75c5\u6210\u4eba\u60a3\u8005\uff08N=360\uff09\u4e2d\u5728\u4f18\u5316RASi\u7597\u6cd5\u57fa\u7840\u4e0aNEFECON\u6bcf\u65e5\u4e00\u6b21\u7ed9\u836f\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002<\/p>\n<p><span id=\"spanHghlt1424\">\u8be5\u7814\u7a76\u7684A\u90e8\u5206\u5305\u62ec200\u540d\u60a3\u8005\u4e3a\u671f9\u4e2a\u6708\u7684\u53cc\u76f2\u6cbb\u7597\u671f\u548c\u4e3a\u671f3\u4e2a\u6708\u7684\u968f\u8bbf\u671f\u3002\u4e3b\u8981\u7ec8\u70b9\u4e3aUPCR \uff08\u5c3f\u86cb\u767d\u808c\u9150\u6bd4\u7387\uff09\uff0c\u6b21\u8981\u7ec8\u70b9\u4e3aeGFR\uff08\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff09\u3002B\u90e8\u5206\u662f\u4e00\u9879\u6b63\u5728\u8fdb\u884c\u7684\u786e\u8bc1\u6027\u9a8c\u8bc1\u7814\u7a76\uff0c\u5c06\u8bc4\u4f30\u5168\u90e8360\u540d\u60a3\u8005\u5728\u4e24\u5e74\u671f\u95f4eGFR\u7684\u53d8\u5316\u3002<\/span> <\/p>\n<p>\u8be5\u5168\u7403\u4e34\u5e8a\u7814\u7a76\u7684A\u90e8\u5206\u8fbe\u5230\u4e86\u5176\u4e3b\u8981\u7ec8\u70b9\uff0c\u5373\u8bc1\u660e\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0cNEFECON 16 mg\u6bcf\u65e5\u7ed9\u836f\u4e00\u6b21\u6cbb\u75979\u4e2a\u6708\u540e\uff0c\u5c3f\u86cb\u767d\u808c\u9150\u6bd4\u7387\uff08UPCR\uff09\u6216\u86cb\u767d\u5c3f\u51fa\u73b0\u7edf\u8ba1\u5b66\u663e\u8457\u610f\u4e49\u964d\u4f4e\u3002\u57289\u4e2a\u6708\u65f6\uff0c\u63a5\u53d7NEFECON\u52a0RASi\u6cbb\u7597\u7684\u60a3\u8005(n=97)\u8f83\u57fa\u7ebf\u76f8\u6bd4\uff0c\u5c3f\u86cb\u767d\u808c\u9150\u6bd4\u7387\uff08UPCR\uff09\u964d\u4f4e34%\uff08\u5355\u72ec\u63a5\u53d7RASi\u6cbb\u7597\u7684\u60a3\u8005(n=102)\u8f83\u57fa\u7ebf\u76f8\u6bd4\uff0c\u5c3f\u86cb\u767d\u808c\u9150\u6bd4\u7387\uff08UPCR\uff09\u964d\u4f4e5%\uff09\uff0c<span id=\"spanHghltd4c9\">p=0.0001<\/span>\u3002<\/p>\n<p><b>\u5173\u4e8e\u4e91\u9876\u65b0\u8000<\/b><\/p>\n<p>\u4e91\u9876\u65b0\u8000\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u4e9a\u6d32\u5e02\u573a\u5c1a\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u4e91\u9876\u65b0\u8000\u7684\u7ba1\u7406\u56e2\u961f\u5728\u4e9a\u6d32\u53ca\u5168\u7403\u5236\u836f\u4f01\u4e1a\u4ece\u4e8b\u8fc7\u9ad8\u8d28\u91cf\u4e34\u5e8a\u5f00\u53d1\u3001\u836f\u653f\u4e8b\u52a1\u3001\u5316\u5b66\u5236\u9020\u4e0e\u63a7\u5236\uff08CMC\uff09\u3001\u4e1a\u52a1\u53d1\u5c55\u548c\u8fd0\u8425\uff0c\u62e5\u6709\u6df1\u539a\u7684\u4e13\u957f\u548c\u4e30\u5bcc\u7684\u7ecf\u9a8c\u3002\u4e91\u9876\u65b0\u8000\u5df2\u6253\u902011\u6b3e\u6709\u6f5c\u529b\u6210\u4e3a\u5168\u7403\u540c\u7c7b\u9996\u521b\u6216\u8005\u540c\u7c7b\u6700\u4f73\u7684\u836f\u7269\u7ec4\u5408\uff0c\u5176\u4e2d\u5927\u90e8\u5206\u5df2\u7ecf\u5904\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u540e\u671f\u9636\u6bb5\u3002\u516c\u53f8\u7684\u6cbb\u7597\u9886\u57df\u5305\u62ec\u80bf\u7624\u3001\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u5fc3\u80be\u75be\u75c5\u3001\u611f\u67d3\u6027\u548c\u4f20\u67d3\u6027\u75be\u75c5\u3002\u6709\u5173\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a<a 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