{"id":66836,"date":"2022-04-04T20:38:00","date_gmt":"2022-04-04T13:38:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022040420380066836"},"modified":"2022-04-05T18:14:22","modified_gmt":"2022-04-05T10:14:22","slug":"sirnaomics%e6%b2%bb%e7%96%97%e5%8e%9f%e5%8f%91%e7%a1%ac%e5%8c%96%e6%80%a7%e8%83%86%e7%ae%a1%e7%82%8e%e8%82%9d%e7%ba%a4%e7%bb%b4%e5%8c%96%e7%9a%84stp707%e6%b2%bb%e7%96%97%e8%8d%af%e7%89%a9i%e6%9c%9f","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022040420380066836","title":{"rendered":"Sirnaomics\u6cbb\u7597\u539f\u53d1\u786c\u5316\u6027\u80c6\u7ba1\u708e\u809d\u7ea4\u7ef4\u5316\u7684STP707\u6cbb\u7597\u836f\u7269I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u542f\u52a8\u4e3a\u9996\u4f8b\u53d7\u8bd5\u8005\u7528\u836f"},"content":{"rendered":"

\u9999\u6e2f<\/span>2022\u5e744\u67084\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — Sirnaomics Ltd.\uff08\u201c<\/span>\u516c\u53f8\u201d<\/span>\uff0c\u201c<\/span>Sirnaomics\u201d<\/span><\/b>\uff0c\u80a1\u4efd\u4ee3\u53f7\uff1a2257.HK\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1RNAi\u7597\u6cd5\u884c\u4e1a\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002Sirnaomics\u4eca\u5929\u5ba3\u5e03\uff0c\u516c\u53f8\u7684\u5c0f\u5e72\u6270\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\u5019\u9009\u836f\u7269STP707\u901a\u8fc7\u9759\u8109\u7ed9\u836f\u7528\u4e8e\u539f\u53d1\u786c\u5316\u6027\u80c6\u7ba1\u708e\uff08PSC\uff09\u6cbb\u7597\u7684\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5728\u7f8e\u56fd\u542f\u52a8\uff0c\u5e76\u5df2\u4e3a\u9996\u4f8b\u53d7\u8bd5\u8005\u8fdb\u884c\u7cfb\u7edf\u7ed9\u836f\u3002<\/p>\n

\u6b64\u9879\u5355\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u5242\u91cf\u9012\u589e\u3001\u987a\u5e8f\u961f\u5217\u7814\u7a76\u65e8\u5728\u8bc4\u4f30STP707\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u836f\u4ee3\u836f\u52a8\uff0c\u5e76\u5728\u5065\u5eb7\u5fd7\u613f\u8005\u4e2d\u4ee5\u5355\u6b21\u9012\u589e\u5242\u91cf\u9759\u8109\u5185\u7ed9\u836f\u3002\u53d7\u8bd5\u8005\u5206\u4e3a\u56db\u7ec4\uff0c\u5176\u4e2dA\u7ec4\u5c06\u901a\u8fc7\u9759\u8109\u8f93\u6ce8\u63a5\u53d73mg\u5242\u91cf\uff0cB\u7ec4\u5c06\u63a5\u53d76mg\uff0cC\u7ec4\u5c06\u63a5\u53d712mg\uff0cD\u7ec4\u5c06\u63a5\u53d724mg\u3002\u8be5\u7814\u7a76\u62db\u52df\u4e86\u591a\u8fbe50\u540d\u5e74\u9f84\u572818\u81f355\u5c81\u4e4b\u95f4\u7684\u5065\u5eb7\u53d7\u8bd5\u8005\u3002<\/p>\n

Sirnaomics\u6267\u884c\u8463\u4e8b\u517c\u9996\u5e2d\u533b\u7597\u5b98Michael Molyneaux\u535a\u58eb\u8bf4\uff1a\u201c\u8fd9\u9879I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u662f\u6211\u4eec\u6cbb\u7597\u809d\u7ea4\u7ef4\u5316\u836f\u7269\u5f00\u53d1\u8ba1\u5212\u4e2d\u975e\u5e38\u91cd\u8981\u7684\u4e00\u6b65\uff0c\u5b83\u5c06\u4f7f\u6211\u4eec\u80fd\u591f\u6536\u96c6\u6709\u5173\u5b89\u5168\u6027\u548c\u5242\u91cf\u7684\u91cd\u8981\u6570\u636e\uff0c\u8fd9\u4e9b\u6570\u636e\u5c06\u652f\u6301\u6211\u4eec\u672a\u6765\u5229\u7528STP707\u6cbb\u7597\u7531\u4e8e\u539f\u53d1\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\u5f15\u8d77\u7684\u809d\u7ea4\u7ef4\u5316\u7684\u7814\u7a76\u3002\u8fd9\u9879\u7814\u7a76\u5c06\u4f7f\u6211\u4eec\u80fd\u591f\u6269\u5927\u5bf9\u8fd9\u79cd\u6cbb\u7597\u5019\u9009\u836f\u7269\u5982\u4f55\u5f71\u54cd\u66f4\u591a\u9700\u8981\u6709\u6548\u6cbb\u7597\u7684\u7f55\u89c1\u75be\u75c5\u60a3\u8005\u7684\u4e86\u89e3\u3002\u201d<\/span><\/p>\n

Sirnaomics\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u3001\u6267\u884c\u8463\u4e8b\u3001\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u9646\u9633\u535a\u58eb\u8868\u793a\uff1a\u201c<\/span>\u8bc4\u4f30STP707\u7528\u4e8e\u6cbb\u7597\u539f\u53d1\u786c\u5316\u6027\u80c6\u7ba1\u708e\u8fd9\u4e00\u6700\u4e3a\u4e25\u91cd\u7684\u809d\u7ea4\u7ef4\u5316\u7c7b\u578b\u7814\u7a76\uff0c\u5c06\u4e3a\u60a3\u6709\u5404\u79cd\u7c7b\u578b\u809d\u7ea4\u7ef4\u5316\u7684\u5e9e\u5927\u60a3\u8005\u7fa4\u4f53\u5e26\u6765\u5e0c\u671b\uff0c\u4e14\u5177\u6709\u5de8\u5927\u7684\u533b\u7597\u9700\u6c42\u3002\u6b64\u6b21\u7814\u7a76\u662fSirnaomics\u5f00\u53d1\u8fd9\u79cdsiRNA\u6cbb\u7597\u4ea7\u54c1\u7528\u4e8e\u6162\u6027\u75c5\u6cbb\u7597\u7684\u9759\u8109\u8f93\u6ce8\u914d\u65b9\u7684\u5173\u952e\u91cc\u7a0b\u7891\u3002\u201d<\/span><\/p>\n

\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8eSirnaomics\u4e34\u5e8a\u8bd5\u9a8c\u4fe1\u606f\uff0c\u8bf7\u6d4f\u89c8\u516c\u53f8\u5b98\u65b9\u7f51\u7ad9\uff1awww.sirnaomics.com<\/a>\u3002<\/p>\n

\u5173\u4e8e<\/b>STP707<\/b><\/p>\n

STP707\u7531\u4e24\u4e2a\u5c0f\u5e72\u6270\u6838\u9178\uff08siRNAs\uff09\u7ec4\u6210\uff0c\u5206\u522b\u9776\u5411TGF-\u03b21\u548cCOX-2 mRNA\uff0c\u5e76\u4e0e\u4e13\u6709\u7684\u7ec4\u6c28\u9178-\u8d56\u6c28\u9178\u5171\u805a\u80bd\uff08HKP+H\uff09\u914d\u5236\u6210\u7eb3\u7c73\u9897\u7c92\u5236\u5242\u4f5c\u4e3a\u7ed9\u836f\u8f7d\u4f53\u3002\u8fd9\u4e00\u7279\u6b8a\u8f7d\u4f53\u4e0eSTP705\u4ea7\u54c1\u4e2d\u4f7f\u7528\u7684\u8f7d\u4f53\u4e0d\u540c\u3002\u6bcf\u4e2a\u5355\u72ec\u7684siRNA\u90fd\u5177\u5907\u6291\u5236\u76f8\u5e94\u9776\u70b9mRNA\u8868\u8fbe\u7684\u80fd\u529b\uff0c\u5e76\u53ef\u5c06\u8fd9\u4e24\u4e2asiRNA\u8054\u5408\u4f7f\u7528\u800c\u4ea7\u751f\u534f\u540c\u6548\u5e94\u3002TGF-\u03b21\u548cCOX-2\u7684\u8fc7\u5ea6\u8868\u8fbe\u5728\u80bf\u7624\u5f62\u6210\u4e2d\u8d77\u7740\u5173\u952e\u7684\u8c03\u8282\u4f5c\u7528\u3002\u5728STP707\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\uff0c\u9759\u8109\u6ce8\u5c04\u7ed9\u836f\u540e\u53ef\u89c2\u5bdf\u5230\u5305\u62ec\u809d\u810f\u548c\u80ba\u7b49\u5668\u5b98\u4e2d\u7684TGF-\u03b21\u548cCOX-2\u57fa\u56e0\u8868\u8fbe\u88ab\u6572\u4f4e\u3002\u6b64\u5916\uff0c\u5728\u4e34\u5e8a\u524d\u6a21\u578b\u8bd5\u9a8c\u4e2d\uff0cSTP707\u663e\u793a\u51fa\u5bf9\u591a\u79cd\u5b9e\u4f53\u80bf\u7624\u7c7b\u578b\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002<\/p>\n

\u5173\u4e8e<\/b>Sirnaomics<\/b><\/p>\n

Sirnaomics\u662f\u4e00\u5bb6RNA\u7597\u6cd5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u516c\u53f8\u5019\u9009\u4ea7\u54c1\u5904\u4e8e\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u9636\u6bb5\uff0c\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1\u521b\u65b0\u836f\u7269\uff0c\u7528\u4e8e\u6cbb\u7597\u5b58\u5728\u533b\u7597\u9700\u6c42\u53ca\u5e9e\u5927\u5e02\u573a\u673a\u4f1a\u7684\u9002\u5e94\u75c7\u3002Sirnaomics\u662f\u5728\u4e2d\u56fd\u548c\u7f8e\u56fd\u5747\u62e5\u6709\u91cd\u8981\u5e02\u573a\u5730\u4f4d\u7684\u9996\u5bb6\u4e34\u5e8a\u9636\u6bb5RNA\u7597\u6cd5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e14\u662f\u9996\u5bb6\u4e3a\u6838\u5fc3\u4ea7\u54c1STP705\u7684RNAi\u7597\u6cd5\u5728\u80bf\u7624\u5b66\u9886\u57df\u53d6\u5f97\u79ef\u6781IIa\u671f\u4e34\u5e8a\u7ed3\u679c\u7684\u516c\u53f8\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u516c\u53f8\u4fe1\u606f\uff0c\u53ef\u6d4f\u89c8\uff1awww.sirnaomics.com<\/a>\u3002<\/p>\n

\u8054\u7cfb\u65b9\u5f0f\uff1a<\/b><\/p>\n

Michael Molyneaux<\/span>, MD, MBA
Sirnaomics \u6267\u884c\u8463\u4e8b\u517c\u9996\u5e2d\u533b\u7597\u5b98
\u7535\u90ae\uff1amichaelmolyneaux@sirnaomics.com<\/a><\/p>\n

\u6295\u8d44\u8005\u5173\u7cfb\uff1a<\/b><\/p>\n

\u53f6\u6c38\u57fa
Sirnaomics\u4e2d\u56fd\u533a\u9996\u5e2d\u8d22\u52a1\u5b98
\u7535\u90ae\uff1aNigelYip@sirnaomics.com<\/a><\/p>\n

\u7f8e\u56fd\u4f20\u5a92\u67e5\u8be2\uff1a<\/b><\/p>\n

Mark Corbae<\/span>
\u7535\u8bdd\uff1a+1 203 682 8288 
\u7535\u90ae\uff1aMark.Corbae@westwicke.com<\/a><\/p>\n

\u4e9a\u6d32\u4f20\u5a92\u67e5\u8be2\uff1a<\/b><\/p>\n

\u674e\u8000\u8363
\u7535\u8bdd\uff1a+852 3150 6707
\u7535\u90ae\uff1asirnaomics.hk@pordahavas.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\u9999\u6e2f2022\u5e744\u67084\u65e5 \/\u7f8e\u901a\u793e\/ — Sirnaomics Ltd.\uff08\u201c\u516c\u53f8\u201d\uff0c\u201cSirnaomics\u201d\uff0c\u80a1\u4efd\u4ee3\u53f7\uff1a2257.HK\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1RNAi\u7597\u6cd5\u884c\u4e1a\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002Sirnaomics\u4eca\u5929\u5ba3\u5e03\uff0c\u516c\u53f8\u7684\u5c0f\u5e72\u6270\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\u5019\u9009\u836f\u7269STP707\u901a\u8fc7\u9759\u8109\u7ed9\u836f\u7528\u4e8e\u539f\u53d1\u786c\u5316\u6027\u80c6\u7ba1\u708e\uff08PSC\uff09\u6cbb\u7597\u7684\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5728\u7f8e\u56fd\u542f\u52a8\uff0c\u5e76\u5df2\u4e3a\u9996\u4f8b\u53d7\u8bd5\u8005\u8fdb\u884c\u7cfb\u7edf\u7ed9\u836f\u3002 \u6b64\u9879\u5355\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u5242\u91cf\u9012\u589e\u3001\u987a\u5e8f\u961f\u5217\u7814\u7a76\u65e8\u5728\u8bc4\u4f30STP707\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u836f\u4ee3\u836f\u52a8\uff0c\u5e76\u5728\u5065\u5eb7\u5fd7\u613f\u8005\u4e2d\u4ee5\u5355\u6b21\u9012\u589e\u5242\u91cf\u9759\u8109\u5185\u7ed9\u836f\u3002\u53d7\u8bd5\u8005\u5206\u4e3a\u56db\u7ec4\uff0c\u5176\u4e2dA\u7ec4\u5c06\u901a\u8fc7\u9759\u8109\u8f93\u6ce8\u63a5\u53d73mg\u5242\u91cf\uff0cB\u7ec4\u5c06\u63a5\u53d76mg\uff0cC\u7ec4\u5c06\u63a5\u53d712mg\uff0cD\u7ec4\u5c06\u63a5\u53d724mg\u3002\u8be5\u7814\u7a76\u62db\u52df\u4e86\u591a\u8fbe50\u540d\u5e74\u9f84\u572818\u81f355\u5c81\u4e4b\u95f4\u7684\u5065\u5eb7\u53d7\u8bd5\u8005\u3002 Sirnaomics\u6267\u884c\u8463\u4e8b\u517c\u9996\u5e2d\u533b\u7597\u5b98Michael Molyneaux\u535a\u58eb\u8bf4\uff1a\u201c\u8fd9\u9879I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u662f\u6211\u4eec\u6cbb\u7597\u809d\u7ea4\u7ef4\u5316\u836f\u7269\u5f00\u53d1\u8ba1\u5212\u4e2d\u975e\u5e38\u91cd\u8981\u7684\u4e00\u6b65\uff0c\u5b83\u5c06\u4f7f\u6211\u4eec\u80fd\u591f\u6536\u96c6\u6709\u5173\u5b89\u5168\u6027\u548c\u5242\u91cf\u7684\u91cd\u8981\u6570\u636e\uff0c\u8fd9\u4e9b\u6570\u636e\u5c06\u652f\u6301\u6211\u4eec\u672a\u6765\u5229\u7528STP707\u6cbb\u7597\u7531\u4e8e\u539f\u53d1\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\u5f15\u8d77\u7684\u809d\u7ea4\u7ef4\u5316\u7684\u7814\u7a76\u3002\u8fd9\u9879\u7814\u7a76\u5c06\u4f7f\u6211\u4eec\u80fd\u591f\u6269\u5927\u5bf9\u8fd9\u79cd\u6cbb\u7597\u5019\u9009\u836f\u7269\u5982\u4f55\u5f71\u54cd\u66f4\u591a\u9700\u8981\u6709\u6548\u6cbb\u7597\u7684\u7f55\u89c1\u75be\u75c5\u60a3\u8005\u7684\u4e86\u89e3\u3002\u201d 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