{"id":66668,"date":"2022-04-01T11:28:00","date_gmt":"2022-04-01T04:28:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022040111280066668"},"modified":"2022-04-01T18:47:39","modified_gmt":"2022-04-01T10:47:39","slug":"%e6%81%92%e7%91%9e%e5%8c%bb%e8%8d%af%e5%8d%a1%e7%91%9e%e5%88%a9%e7%8f%a0%e5%8d%95%e6%8a%97%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e6%88%90%e6%9e%9c%e5%86%8d%e7%99%bb%e6%ac%a7%e6%b4%b2%e8%82%ba%e7%99%8c","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022040111280066668","title":{"rendered":"\u6052\u745e\u533b\u836f\u5361\u745e\u5229\u73e0\u5355\u6297\u6700\u65b0\u7814\u7a76\u6210\u679c\u518d\u767b\u6b27\u6d32\u80ba\u764c\u5927\u4f1a"},"content":{"rendered":"

\u9cde\u72b6NSCLC\u6cbb\u7597\u53d6\u5f97\u65b0\u7a81\u7834\uff01<\/p>\n

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2020\u5e74\uff0c\u57fa\u4e8eCameL\u7814\u7a76\u7684\u7a81\u7834\u6027\u6570\u636e\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u6210\u4e3a\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u6307\u5357\u4e2d\u63a8\u8350\u7684\u9996\u4e2a\u665a\u671f\u9a71\u52a8\u57fa\u56e0\u9634\u6027\u975e\u9cdeNSCLC\u4e00\u7ebf\u6807\u51c6\u6cbb\u7597\u56fd\u4ea7PD-1\u5355\u6297\uff0c\u5e76\u6210\u4e3a\u9996\u4e2a\u83b7\u6279\u9a71\u52a8\u57fa\u56e0\u9634\u6027\u665a\u671f\u975e\u9cdeNSCLC\u9002\u5e94\u75c7\u7684\u4e2d\u56fd\u81ea\u4e3b\u7814\u53d1\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff0c\u4e14\u4ec5\u65f6\u9694\u534a\u5e74\uff0c\u5373\u88ab\u5feb\u901f\u7eb3\u5165\u4e86\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\uff0c\u6210\u4e3a\u80ba\u764c\u9886\u57df\u9996\u4e2a\u53ef\u62a5\u9500\u7684\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff0c\u8db3\u89c1\u5176\u8feb\u5207\u7684\u4e34\u5e8a\u9700\u6c42\u548c\u7a81\u51fa\u7684\u4e34\u5e8a\u4ef7\u503c\u3002CameL\u7814\u7a76\u4e5f\u83b7\u5f97\u4e86\u56fd\u9645\u5b66\u672f\u754c\u9ad8\u5ea6\u8ba4\u53ef\uff0c\u591a\u6b21\u91cd\u78c5\u4eae\u76f8\u4e8e\u5404\u7c7b\u56fd\u9645\u80bf\u7624\u5b66\u5927\u4f1a\uff0c\u5e76\u4e8e2020\u5e7412\u6708\u8363\u767b\u56fd\u9645\u6743\u5a01\u5b66\u672f\u671f\u520a\u300a\u67f3\u53f6\u5200·\u547c\u5438\u533b\u5b66\u300b\uff08THE LANCET Respiratory Medicine\uff09[5]<\/sup>\u3002<\/p>\n

2021\u5e74\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u518d\u521b\u8f89\u714c\uff0c\u57fa\u4e8eCameL-sq\u7814\u7a76\u7684\u51fa\u8272\u6570\u636e\uff0c\u88abCSCO\u6307\u5357\u63a8\u8350\u4e3a\u9a71\u52a8\u57fa\u56e0\u9634\u6027\u665a\u671f\u80ba\u9cde\u764c\u514d\u75ab\u8054\u5408\u5316\u7597\u6807\u51c6\u4e00\u7ebf\u6cbb\u7597\uff1b\u5e76\u4e8e12\u6708\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u76f8\u5e94\u9002\u5e94\u75c7\uff0c\u7531\u6b64\u5168\u9762\u8986\u76d6\u4e86\u9a71\u52a8\u57fa\u56e0\u9634\u6027\u665a\u671fNSCLC\u4e00\u7ebf\u6cbb\u7597\u3002\u56fd\u9645\u821e\u53f0\u4e0a\uff0cCameL-sq\u7814\u7a76\u4e5f\u5c61\u83b7\u6b8a\u8363\uff0c\u5176\u6210\u679c\u5df2\u5148\u540e\u53d1\u8868\u4e8eJournal of Thoracic Oncology[6]<\/sup>\u548cMolecular Cancer\u6742\u5fd7[7]<\/sup>\u3002<\/p>\n

\u622a\u81f3\u76ee\u524d\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u5df2\u5728\u80ba\u764c\u3001\u809d\u764c\u3001\u98df\u7ba1\u764c\u3001\u9f3b\u54bd\u764c\u548c\u6dcb\u5df4\u7624\u4e94\u5927\u7624\u79cd\u9886\u57df\u5171\u83b7\u6279\u4e86<\/b>8\u9879\u9002\u5e94\u75c7\uff0c\u9886\u8dd1\u56fd\u4ea7PD-1\u5355\u6297<\/b>\uff0c\u4e14\u591a\u9879\u9002\u5e94\u75c7\u5df2\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\uff0c\u4f7f\u836f\u7269\u53ef\u53ca\u6027\u5927\u5927\u63d0\u9ad8\u3002<\/p>\n

\u672a\u6765\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u5c06\u52aa\u529b\u5728\u66f4\u5e7f\u6cdb\u7684\u7624\u79cd\u9886\u57df\u3001\u66f4\u4e30\u5bcc\u7684\u6cbb\u7597\u65f6\u673a\u3001\u66f4\u591a\u6837\u7684\u8054\u5408\u65b9\u6848\u63a2\u7d22\u4e2d\u518d\u521b\u4f73\u7ee9\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u591a\u83b7\u76ca\u3002<\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

\n\n\n\n\n\n\n
\n

[1\u30012\u30013\u30014] <\/sup>Zhou CC, et al., 2022 ELCC 3MO <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[5] <\/sup>Zhou C, Chen G, Huang Y, et al. Lancet Respir Med. 2021;9(3):305-314<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[6] <\/sup>Ren S, Chen J, Xu X, et al. J Thorac Oncol. 2022;17(4):544-557<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[7] <\/sup>Jiang T, Chen J, Xu X, et al. Mol Cancer. 2022;21(1):4<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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LANCET Respiratory Medicine\uff09[5]\u3002 2021\u5e74\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u518d\u521b\u8f89\u714c\uff0c\u57fa\u4e8eCameL-sq\u7814\u7a76\u7684\u51fa\u8272\u6570\u636e\uff0c\u88abCSCO\u6307\u5357\u63a8\u8350\u4e3a\u9a71\u52a8\u57fa\u56e0\u9634\u6027\u665a\u671f\u80ba\u9cde\u764c\u514d\u75ab\u8054\u5408\u5316\u7597\u6807\u51c6\u4e00\u7ebf\u6cbb\u7597\uff1b\u5e76\u4e8e12\u6708\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u76f8\u5e94\u9002\u5e94\u75c7\uff0c\u7531\u6b64\u5168\u9762\u8986\u76d6\u4e86\u9a71\u52a8\u57fa\u56e0\u9634\u6027\u665a\u671fNSCLC\u4e00\u7ebf\u6cbb\u7597\u3002\u56fd\u9645\u821e\u53f0\u4e0a\uff0cCameL-sq\u7814\u7a76\u4e5f\u5c61\u83b7\u6b8a\u8363\uff0c\u5176\u6210\u679c\u5df2\u5148\u540e\u53d1\u8868\u4e8eJournal of Thoracic Oncology[6]\u548cMolecular Cancer\u6742\u5fd7[7]\u3002 \u622a\u81f3\u76ee\u524d\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u5df2\u5728\u80ba\u764c\u3001\u809d\u764c\u3001\u98df\u7ba1\u764c\u3001\u9f3b\u54bd\u764c\u548c\u6dcb\u5df4\u7624\u4e94\u5927\u7624\u79cd\u9886\u57df\u5171\u83b7\u6279\u4e868\u9879\u9002\u5e94\u75c7\uff0c\u9886\u8dd1\u56fd\u4ea7PD-1\u5355\u6297\uff0c\u4e14\u591a\u9879\u9002\u5e94\u75c7\u5df2\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\uff0c\u4f7f\u836f\u7269\u53ef\u53ca\u6027\u5927\u5927\u63d0\u9ad8\u3002 \u672a\u6765\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u5c06\u52aa\u529b\u5728\u66f4\u5e7f\u6cdb\u7684\u7624\u79cd\u9886\u57df\u3001\u66f4\u4e30\u5bcc\u7684\u6cbb\u7597\u65f6\u673a\u3001\u66f4\u591a\u6837\u7684\u8054\u5408\u65b9\u6848\u63a2\u7d22\u4e2d\u518d\u521b\u4f73\u7ee9\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u591a\u83b7\u76ca\u3002 \u53c2\u8003\u6587\u732e\uff1a [1\u30012\u30013\u30014] Zhou CC, et al., 2022 ELCC 3MO  [5] Zhou C, Chen G, Huang Y, et al. 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