{"id":65632,"date":"2022-03-23T07:05:00","date_gmt":"2022-03-23T00:05:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022032307050065632"},"modified":"2022-03-23T18:01:27","modified_gmt":"2022-03-23T10:01:27","slug":"%e8%af%ba%e8%af%9a%e5%81%a5%e5%8d%8e%e5%8f%91%e5%b8%832021%e5%b9%b4%e4%b8%9a%e7%bb%a9%e6%8a%a5%e5%91%8a%ef%bc%9a%e5%95%86%e4%b8%9a%e5%8c%96%e3%80%81%e5%9b%bd%e9%99%85%e5%8c%96%e3%80%81%e5%88%9b","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022032307050065632","title":{"rendered":"\u8bfa\u8bda\u5065\u534e\u53d1\u5e032021\u5e74\u4e1a\u7ee9\u62a5\u544a\uff1a\u5546\u4e1a\u5316\u3001\u56fd\u9645\u5316\u3001\u521b\u65b0\u5316\uff0c\u4e09\u8f6e\u9a71\u52a8\u52a0\u901f\u53d1\u5c55"},"content":{"rendered":"<p><p>\u5317\u4eac2022\u5e743\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u4eca\u65e5\u53d1\u5e03\u622a\u81f32021\u5e7412\u670831\u65e5\u76842021\u5e74\u4e1a\u7ee9\u62a5\u544a\u548c\u516c\u53f8\u8fdb\u5c55\u3002<\/p>\n<p>\u8bfa\u8bda\u5065\u534e\u8054\u5408\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98<b>\u5d14\u9701\u677e\u535a\u58eb<\/b>\u8bf4\uff1a\u201c\u5f88\u9ad8\u5174\u5728\u6211\u4eec\u6e2f\u4ea4\u6240\u4e0a\u5e02\u4e24\u5468\u5e74\u4e4b\u9645\u53d1\u5e03\u516c\u53f82021\u5e74\u4e1a\u7ee9\u62a5\u544a\u30022021\u5e74\u662f\u4e0d\u5e73\u51e1\u7684\u4e00\u5e74\u3002\u6211\u4eec\u514b\u670d\u5404\u79cd\u56f0\u96be\u548c\u6311\u6218\uff0c\u5b9e\u73b0\u516c\u53f8\u53d1\u5c55\u5386\u53f2\u4e0a\u591a\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\u3002\u6211\u4eec\u5728\u5546\u4e1a\u5316\u5143\u5e74\u53d6\u5f97\u4ee4\u4eba\u6ee1\u610f\u7684\u6210\u7ee9\uff0c\u5965\u5e03\u66ff\u5c3c2021\u5e74\u5e95\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u5c06\u60e0\u53ca\u66f4\u591a\u60a3\u8005\uff1b\u6211\u4eec\u5728\u56fd\u9645\u5316\u8fdb\u5c55\u65b9\u9762\u53d6\u5f97\u91cd\u5927\u7a81\u7834\uff0c\u4e0e\u6e24\u5065\u548cIncyte\u516c\u53f8\u5206\u522b\u8fbe\u6210license-out\u548clicense-in\u7684\u91cd\u8981\u5408\u4f5c\uff1b\u6211\u4eec\u5728\u521b\u65b0\u9886\u57df\u6301\u7eed\u6df1\u8015\uff0c\u540c\u65f6\u4e0d\u65ad\u63a8\u8fdb\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e0c\u671b\u66f4\u591a\u5728\u7814\u521b\u65b0\u836f\u65e9\u65e5\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u2026\u2026\u201d<\/p>\n<p><b>\u4e3b\u8981\u8d22\u52a1\u4e1a\u7ee9\u6458\u8981<\/b><\/p>\n<ul type=\"disc\">\n<li>\u516c\u53f8\u6536\u5165\u4ece2020\u5e74\u7684140\u4e07\u5143\u5927\u5e45\u4e0a\u6da8\u81f32021\u5e74\u768410.43\u4ebf\u5143\uff0c\u4e3b\u8981\u5f97\u76ca\u4e8e\u5965\u5e03\u66ff\u5c3c\u7684\u9500\u552e\u6536\u5165\u548c\u6e24\u5065\u7684\u9996\u4ed8\u6b3e\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u7814\u53d1\u8d39\u7528\u4ece2020\u5e74\u76844.028\u4ebf\u5143\u589e\u81f32021\u5e74\u76847.216\u4ebf\u5143\uff0c\u4e3b\u8981\u662f\u589e\u52a0\u4e86license-in tafasitamab\u7684\u9996\u4ed8\u6b3e\u7b49\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u516c\u53f8\u73b0\u91d1\u548c\u73b0\u91d1\u7b49\u4ef7\u7269\u4ece2020\u5e74\u5e74\u5e95\u768439.696\u4ebf\u5143\u589e\u81f32021\u5e74\u5e74\u5e95\u768465.505\u4ebf\u5143\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u516c\u53f8\u4e8f\u635f\u5728\u62a5\u544a\u671f\u5185\u540c\u6bd4\u5927\u5e45\u4e0b\u964d\uff0c\u75312020\u5e74\u76843.919\u4ebf\u5143\u51cf\u5c11\u81f32021\u5e74\u76846670\u4e07\u5143\uff0c\u4e3b\u8981\u662f\u6e90\u4e8e\u6536\u5165\u589e\u52a0\u3002<\/li>\n<\/ul>\n<p>\uff08\u6ce8\uff1a\u8d27\u5e01\u4e3a\u4eba\u6c11\u5e01\uff0c\u8bfa\u8bda\u5065\u534e\u8d22\u52a1\u5e74\u5ea6\u6307\u7684\u662f\u67d0\u4e00\u5e74\u76841\u67081\u65e5\u523012\u670831\u65e5\u3002\uff09<\/p>\n<p><b>\u5173\u952e\u4eae\u70b9\u548c\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/b><\/p>\n<p><b>\u5e03\u9c81\u987f\u916a\u6c28\u9178\u6fc0\u9176\uff08<\/b><b>BTK<\/b><b>\uff09\u6291\u5236\u5242\u5965\u5e03\u66ff\u5c3c<\/b><\/p>\n<p><b>\u5546\u4e1a\u5316\u8fdb\u5c55<\/b> <\/p>\n<ul type=\"disc\">\n<li>\u8bfa\u8bda\u5065\u534e2021\u5e741\u6708\u4e2d\u5f00\u51fa\u9996\u6b3e\u5546\u4e1a\u5316\u4ea7\u54c1\u5965\u5e03\u66ff\u5c3c\u7684\u5168\u56fd\u9996\u65b9\u3002\u8bfa\u8bda\u5065\u534e\u5df2\u5efa\u7acb250\u540d\u7ecf\u9a8c\u4e30\u5bcc\u7684\u5546\u4e1a\u5316\u56e2\u961f\u3002\u622a\u81f32021\u5e7412\u670831\u65e5\uff0c\u5df2\u7ecf\u8fc5\u901f\u8986\u76d6260\u591a\u4e2a\u57ce\u5e02\u76841000\u591a\u5bb6\u533b\u9662\uff0c\u5b9e\u73b02.41\u4ebf\u5143\u4eba\u6c11\u5e01\u7684\u603b\u9500\u552e\uff08Gross Revenue\uff09\u3002 <\/li>\n<li>2021\u5e7412\u6708\uff0c\u5965\u5e03\u66ff\u5c3c\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\uff0c\u5c06\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u3002<\/li>\n<\/ul>\n<p><b>\u5546\u52a1\u62d3\u5c55<\/b> <\/p>\n<ul type=\"disc\">\n<li>\u8bfa\u8bda\u5065\u534e\u4e0e\u6e24\u5065\u5c31\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u591a\u53d1\u6027\u786c\u5316\uff08MS\uff09\u8fbe\u6210\u8bb8\u53ef\u53ca\u5408\u4f5c\u534f\u8bae\uff0c\u8bfa\u8bda\u5065\u534e\u56e0\u6b64\u4e8e2021\u5e749\u6708\u6536\u5230\u6e24\u50651.25\u4ebf\u7f8e\u5143\u9996\u4ed8\u6b3e\u3002\u6b64\u5916\uff0c\u5728\u8fbe\u5230\u5408\u4f5c\u7ea6\u5b9a\u7684\u5f00\u53d1\u91cc\u7a0b\u7891\u3001\u5546\u4e1a\u5316\u91cc\u7a0b\u7891\u65f6\uff0c\u8bfa\u8bda\u5065\u534e\u6709\u8d44\u683c\u83b7\u5f97\u81f3\u591a8.125\u4ebf\u7f8e\u5143\u7684\u6f5c\u5728\u4e34\u5e8a\u5f00\u53d1\u91cc\u7a0b\u7891\u548c\u5546\u4e1a\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u8bfa\u8bda\u5065\u534e\u8fd8\u5c06\u6709\u8d44\u683c\u83b7\u5f97\u6f5c\u5728\u672a\u6765\u51c0\u9500\u552e\u989d\u767e\u5206\u4e4b\u5341\u51e0\u8303\u56f4\u5185\u4ece\u4f4e\u81f3\u9ad8\u7684\u5206\u5c42\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u3002 <\/li>\n<li>\u76ee\u524d\uff0c\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u591a\u53d1\u6027\u786c\u5316\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u7f8e\u56fd\u3001\u6b27\u6d32\u548c\u4e2d\u56fd\u5f00\u5c55\u3002<\/li>\n<\/ul>\n<p><b>\u7814\u53d1\u8fdb\u5c55<\/b><\/p>\n<p><b>\u5965\u5e03\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08<\/b><b>SLE<\/b><b>\uff09<\/b><\/p>\n<ul type=\"disc\">\n<li>\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e8e2021\u5e74\u5e74\u5e95\u5b8c\u6210\u3002 <\/li>\n<li>\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u8f7b\u4e2d\u5ea6\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u60a3\u8005\u53e3\u670d\u5965\u5e03\u66ff\u5c3c\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u826f\u597d\u3002\u5728\u6240\u6709\u63a5\u53d7\u6cbb\u7597\u53ef\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u7597\u6548\u5448\u5242\u91cf\u4f9d\u8d56\u6027\u3002\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5b89\u6170\u5242\u3001\u5965\u5e03\u66ff\u5c3c50\u6beb\u514b\u300180\u6beb\u514b\u548c100\u6beb\u514b\uff0c\u7b2c12\u5468SRI-4\uff08SLE\u5e94\u7b54\u8005\u6307\u65704\uff09\u7684\u5e94\u7b54\u7387\u5206\u522b\u4e3a37.5%\u300150.0%\u300161.5%\u548c64.3%\u3002 <\/li>\n<li>\u5728SLE\u60a3\u8005\u4e2d\uff0c\u5965\u5e03\u66ff\u5c3c\u53ef\u964d\u4f4e\u86cb\u767d\u5c3f\u6c34\u5e73\uff0c\u6539\u5584\u514d\u75ab\u6807\u8bb0\u7269\uff0c\u5305\u62ec\u964d\u4f4e\u514d\u75ab\u7403\u86cb\u767dG\uff0c\u589e\u52a0\u8865\u4f53C3\u548cC4\u3002 <\/li>\n<li>\u8bfa\u8bda\u5065\u534e\u5c06\u7ee7\u7eed\u63a8\u8fdb\u5965\u5e03\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u4e34\u5e8a\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b>\u5965\u5e03\u66ff\u5c3c\u4e00\u7ebf\u6cbb\u7597\u5f25\u6f2b\u6027\u5927<\/b><b>B<\/b><b>\u7ec6\u80de\u6dcb\u5df4\u7624\uff08<\/b><b>DLBCL<\/b><b>\uff09<\/b><b>MCD <\/b><b>\u4e9a\u578b<\/b><\/p>\n<p>\u8bfa\u8bda\u5065\u534e\u6b63\u5728\u5f00\u5c55\u4e00\u9879\u8bc4\u4ef7\u5965\u5e03\u66ff\u5c3c\u8054\u5408R-CHOP \u65b9\u6848\u5bf9\u6bd4\u5b89\u6170\u5242\u8054\u5408R-CHOP \u65b9\u6848\u6cbb\u7597\u4e00\u7ebfMCD \u4e9a\u578b\u5f25\u6f2b\u6027\u5927B \u7ec6\u80de\u6dcb\u5df4\u7624\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u968f\u673a\u3001\u53cc\u76f2\u3001\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3III \u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5c06\u4e3a\u4e00\u7ebfDLBCL\u60a3\u8005\u63d0\u4f9b\u66f4\u597d\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/p>\n<p><b>ICP-B04 (Tafasitamab)<\/b><\/p>\n<ul type=\"disc\">\n<li>2021\u5e748\u6708\uff0c\u8bfa\u8bda\u5065\u534e\u548cIncyte\u516c\u53f8\u5c31\u4e00\u6b3e\u9776\u5411CD19\u7684Fc\u7ed3\u6784\u57df\u4f18\u5316\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53tafasitamab\u5728\u5927\u4e2d\u534e\u533a\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7b7e\u8ba2\u4e86\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\u3002Tafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u5df2\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u548c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7684\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6027\u5f25\u6f2b\u6027\u5927&nbsp;B \u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u60a3\u8005\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u8bfa\u8bda\u5065\u534e\u4e0eIncyte\u7684\u6218\u7565\u5408\u4f5c\u5c06\u4e3a\u63a2\u7d22tafasitamab\u548c\u5965\u5e03\u66ff\u5c3c\u4ee5\u53ca\u8bfa\u8bda\u5065\u534e\u5176\u4ed6\u7ba1\u7ebf\u8054\u5408\u6cbb\u7597B\u7ec6\u80de\u6076\u6027\u80bf\u7624\u63d0\u4f9b\u4e86\u826f\u597d\u7684\u673a\u4f1a\uff0c\u4e5f\u5c06\u589e\u5f3a\u8bfa\u8bda\u5065\u534e\u5728\u8840\u6db2\u7624\u548c\u5b9e\u4f53\u7624\u9886\u57df\u7684\u5b9e\u529b\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>Tafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u5df2\u83b7\u5f97\u6d77\u5357\u7701\u536b\u5065\u59d4\u548c\u836f\u76d1\u5c40\u6279\u51c6\uff0c\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u6cbb\u7597\u7b26\u5408\u6761\u4ef6\u7684DLBCL\u60a3\u8005\u3002<\/li>\n<\/ul>\n<p><b>ICP-192 (Gunagratinib)<\/b><\/p>\n<p>Gunagratinib\u76ee\u524d\u6b63\u5728\u4e2d\u56fd\u548c\u7f8e\u56fd\u8fdb\u884c\u591a\u4e2aI\/II\u671f\u4e34\u5e8a\u7814\u7a76\u3002\u5728\u4e2d\u56fd\uff0c\u5728I\/II\u671f\u8bd5\u9a8c\u7684\u5242\u91cf\u9012\u589e\u90e8\u5206\uff0c\u57282\u523026\u6beb\u514b\u5242\u91cf\u8303\u56f4\u5185\u7684\u6240\u6709\u5242\u91cf\u7ec4\u4e2d\uff0c\u5747\u8bc1\u660e\u4e86gunagratinib\u7684\u826f\u597d\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u672a\u89c2\u5bdf\u5230\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\uff08DLT\uff09\u3002<\/p>\n<ul type=\"disc\">\n<li><b>\u5934\u9888\u764c<br \/><\/b>\u5728\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\u4e2d\uff0c\u5728FGF\/FGFR\u57fa\u56e0\u5f02\u5e38\u7684\u5934\u9888\u764c\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230gunagratinib\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002\u81f3\u5c11\u5b8c\u6210\u4e00\u6b21\u80bf\u7624\u8bc4\u4f30\u76849\u4f8bFGF\/FGFR\u57fa\u56e0\u5f02\u5e38\u60a3\u8005\u4e2d\uff0c\u603b\u7f13\u89e3\u7387\uff08ORR\uff09\u4e3a33.3%\u3002<br \/>2022\u5e74\u5e74\u521d\uff0c\u8bfa\u8bda\u5065\u534e\u542f\u52a8\u4e86\u4e00\u9879\u5305\u62ecFGF\/FGFR\u57fa\u56e0\u5f02\u5e38\u7684\u5934\u9888\u764c\u5728\u5185\u7684\u5b9e\u4f53\u7624\u7bee\u5f0f\u8bd5\u9a8c\u3002 <\/li>\n<li><b>\u80c6\u7ba1\u764c<br \/><\/b>\u5728II\u671f\u8bd5\u9a8c\u4e2d\uff0c20\u6beb\u514b&nbsp;gunagratinib\u5bf9\u80c6\u7ba1\u764c\u60a3\u8005\u663e\u793a\u51fa\u521d\u6b65\u6709\u6548\u6027\u3002\u622a\u81f32022\u5e741\u670813\u65e5\uff0c\u5728\u81f3\u5c11\u5b8c\u6210\u4e00\u9879\u80bf\u7624\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\uff0cORR\u4e3a60%\uff0c\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u4e3a100%\u3002 <\/li>\n<li><b>\u56fd\u9645\u8fdb\u5c55<br \/><\/b>2021\u5e746\u6708\uff0cgunagratinib\u83b7\u5f97\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597\u80c6\u7ba1\u764c\u3002\u8bfa\u8bda\u5065\u534e\u6b63\u5728\u7f8e\u56fd\u548c\u6fb3\u5927\u5229\u4e9a\u5f00\u5c55\u9488\u5bf9\u80c6\u7ba1\u764c\u548c\u5934\u9888\u764c\u5242\u91cf\u9012\u589e\u7684I\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/li>\n<\/ul>\n<p><b>ICP-723<\/b><\/p>\n<ul type=\"disc\">\n<li>\u622a\u81f3&nbsp;2022 \u5e74&nbsp;2 \u6708&nbsp;11 \u65e5\uff0c\u5728&nbsp;I \u671f\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\u4e2d\uff0c\u5171\u6709&nbsp;17 \u4f8b\u60a3\u8005\u63a5\u53d7\u4e86&nbsp;ICP-723 \u7684\u6cbb\u7597\uff0c\u5242\u91cf\u4e3a&nbsp;1\u6beb\u514b\u81f3&nbsp;8\u6beb\u514b\uff0c\u6bcf\u5929\u4e00\u6b21\u3002\u5b89\u5168\u6027\u826f\u597d\uff0c\u6ca1\u6709\u89c2\u5bdf\u5230&nbsp;DLT\u300217\u4f8b\u60a3\u8005\u4e2d\uff0c5\u4f8b\u60a3\u8005\u786e\u8ba4\u4e3aNTRK\u57fa\u56e0\u878d\u5408\u9633\u6027\uff0cORR\u4e3a80%\uff084\u4f8bPR\uff09\uff0cDCR\u4e3a100%\u3002\u57284\u6beb\u514b\u53ca\u4ee5\u4e0a\u5242\u91cf\u7ec4\u4e2d\uff0cORR\u4e3a100%\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u5728\u7f8e\u56fd\uff0cICP-723\u6cbb\u7597NTRK\u878d\u5408\u9633\u6027\u80bf\u7624\u7684\u65b0\u836f\u7814\u7a76\u7533\u8bf7\u4e8e2021\u5e748\u6708\u83b7\u6279\uff0c\u6b63\u5728\u5f00\u5c55I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/li>\n<\/ul>\n<p><b>ICP-332<\/b><\/p>\n<ul type=\"disc\">\n<li>\u65b0\u578b\u916a\u6c28\u9178\u6fc0\u91762\uff08TYK2\uff09\u6291\u5236\u5242I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u7ecf\u5b8c\u6210\uff0c\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u591a\u79cd\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u4ece5\u6beb\u514b\u81f3320\u6beb\u514b\uff0cICP-332\u8bc1\u660e\u4e86\u836f\u4ee3\u52a8\u529b\u5b66\uff08PK\uff09\u53c2\u6570\u4e0e\u5242\u91cf\u6210\u6bd4\u4f8b\u589e\u52a0\uff0c\u6ca1\u6709\u660e\u663e\u7684\u98df\u7269\u6548\u5e94\u3002ICP-332\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u8fbe\u5230\u6700\u5927\u8010\u53d7\u5242\u91cf\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u907f\u514d\u4e86\u5bf9JAK2\u8131\u9776\u4f5c\u7528\u5f15\u8d77\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002<\/li>\n<\/ul>\n<p><b>ICP-B05<\/b><b>\uff08\u65b0\u62ab\u9732\u5728\u7814\u65b0\u836f\uff09<\/b><\/p>\n<ul type=\"disc\">\n<li>ICP-B05\u662f\u4e00\u79cd\u6297\u8d8b\u5316\u56e0\u5b50\u53d7\u4f538\uff08CCR8\uff09\u5355\u514b\u9686\u6297\u4f53\uff0c\u662f\u8bfa\u8bda\u5065\u534e\u548c\u5eb7\u8bfa\u4e9a\u5171\u540c\u5f00\u53d1\u7684\u6f5c\u5728first-in-class\u836f\u7269\uff0c\u53ef\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\u6216\u4e0e\u5176\u4ed6\u7597\u6cd5\u8054\u5408\u6cbb\u7597\u5404\u79cd\u764c\u75c7\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>CCR8\u88ab\u8bc1\u660e\u53ef\u5728\u80bf\u7624\u5fae\u73af\u5883\uff08TME\uff09\u4e2d\u514d\u75ab\u6291\u5236\u6027\u7684\u8c03\u8282\u6027T\u7ec6\u80de\uff08Treg\uff09\u4e0a\u9009\u62e9\u6027\u8fc7\u8868\u8fbe\u3002ICP-B05\u4e0eTreg\u4e0a\u7684CCR8\u7279\u5f02\u6027\u7ed3\u5408\uff0c\u5e76\u901a\u8fc7ADCC\u4f5c\u7528\u6e05\u9664\u514d\u75ab\u6291\u5236\u6027Treg\uff0c\u4ee5\u89e3\u9664TME\u4e2d\u7684\u80bf\u7624\u6291\u5236\uff0c\u800c\u4e0d\u5bf9\u5916\u5468\u7ec4\u7ec7\u4ea7\u751f\u5f71\u54cd\u3002ICP-B05\u9009\u62e9\u6027\u6e05\u9664\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684Treg\uff0c\u6bd4\u5176\u4ed6\u514d\u75ab\u7597\u6cd5\u66f4\u5177\u7279\u5f02\u6027\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>ICP-B05\u7684IND\u7533\u8bf7\u5c06\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u63d0\u4ea4\u3002<\/li>\n<\/ul>\n<p>\u76ee\u524d\uff0c\u8bfa\u8bda\u5065\u534e\u5df2\u7ecf\u5efa\u7acb\u4e86\u5f3a\u5927\u7684\u4ea7\u54c1\u7ba1\u7ebf\u3002\u5176\u4e2d\u5965\u5e03\u66ff\u5c3c\u9664\u83b7\u6279\u4e24\u9879\u9002\u5e94\u75c7\uff0c\u8fd8\u6709\u516d\u9879\u9002\u5e94\u75c7\u5904\u4e8e\u4e2d\u7f8e\u6ce8\u518c\u8bd5\u9a8c\u9636\u6bb5\u3002\u53e6\u5916\uff0c\u8fd8\u6709\u4e5d\u6b3e\u4ea7\u54c1\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\uff0c\u591a\u6b3e\u4ea7\u54c1\u5904\u4e8e\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u6b63\u5728\u5168\u7403\u8fdb\u884c30\u591a\u9879\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p><b>\u5965\u5e03\u66ff\u5c3c\u5176\u4ed6\u4e34\u5e8a\u8fdb\u5c55<\/b><\/p>\n<p><b><u>\u8840\u6db2\u7624<\/u><\/b><\/p>\n<p>\u5965\u5e03\u66ff\u5c3c\u5df2\u88ab\u7eb3\u5165\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u300a2021\u5e74\u6076\u6027\u6dcb\u5df4\u7624\u8bca\u7597\u6307\u5357\u300b\uff0c\u5e76\u88ab\u5217\u4e3a\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6027\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u548c\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08R\/R CLL\/SLL\uff09\u53ca\u590d\u53d1\/\u96be\u6cbb\u6027\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08R\/R MCL\uff09\u7684\u4e00\u7ea7\u63a8\u8350\u65b9\u6848\u3002<\/p>\n<ul type=\"disc\">\n<li><b>R\/R WM: <\/b>\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6027\u534e\u6c0f\u5de8\u7403\u86cb\u767d\u8840\u75c7\uff08WM\uff09\u60a3\u8005\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u5df2\u7ecf\u83b7\u5f97\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u53d7\u7406\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>R\/R MZL: <\/b>\u4e00\u9879\u8bc4\u4f30\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6027\u8fb9\u7f18\u533a\u6dcb\u5df4\u7624\u60a3\u8005\u7684\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u5f0f\u7814\u7a76\u6b63\u5728\u8fdb\u884c\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u968f\u8bbf\uff0c\u5e76\u8ba1\u52122022\u5e74\u4e0a\u534a\u5e74\u63d0\u4ea4\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>R\/R CLL\/SLL: <\/b>\u6839\u636e\u7b2c63\u5c4a\u7f8e\u56fd\u8840\u6db2\u5b66\u534f\u4f1a\uff08ASH\uff09\u5e74\u4f1a\u53d1\u5e03\u7684\u6570\u636e\uff0c\u5728\u76f8\u4f3c\u4e2d\u4f4d\u968f\u8bbf\u671f\u5185\uff0c\u548c\u5176\u4ed6BTK\u6291\u5236\u5242\u76f8\u6bd4\uff0c\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597R\/R CLL\/SLL\u5177\u6709\u66f4\u9ad8\u7684CR\/CRi\u7387\u3002\u7814\u7a76\u8005\u8bc4\u4f30\u7684ORR\u4e3a93.8%\uff0c\u5176\u4e2d\u5b8c\u5168\u7f13\u89e3\/\u4f34\u9aa8\u9ad3\u6062\u590d\u4e0d\u5b8c\u5168\u7684\u5b8c\u5168\u7f13\u89e3\uff08CR\/CRi\uff09\u7387\u4e3a26.3%\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>R\/R MCL: <\/b>\u5728\u7f8e\u56fd\uff0c\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597R\/R MCL \u7684&nbsp;II \u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u9884\u8ba1\u5c06\u4e8e&nbsp;2022 \u5e74\u5b8c\u6210\u60a3\u8005\u5165\u7ec4\u30022021 \u5e74&nbsp;6 \u6708\uff0c\u7f8e\u56fd&nbsp;FDA \u6388\u4e88\u5965\u5e03\u66ff\u5c3c\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597&nbsp;R\/R MCL\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>1L CLL\/SLL: <\/b>\u4e00\u9879\u8bc4\u4ef7\u5965\u5e03\u66ff\u5c3c\u5355\u836f\u6cbb\u7597\u5bf9\u6bd4\u5229\u59a5\u6614\u5355\u6297\u8054\u5408\u82ef\u4e01\u9178\u6c2e\u82a5\u4e00\u7ebf\u6cbb\u7597CLL\/SLL\u7684&nbsp;III \u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u4e2d\u56fd\u8fdb\u884c\uff0c\u9884\u8ba12023\u5e74\u5b8c\u6210\u60a3\u8005\u5165\u7ec4\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>1L MCL: <\/b>\u4e00\u9879\u8bc4\u4ef7\u5965\u5e03\u66ff\u5c3c\u8054\u5408R-CHOP\u65b9\u6848\u5bf9\u6bd4\u5b89\u6170\u5242\u8054\u5408R-CHOP\u65b9\u6848\u4e00\u7ebf\u6cbb\u7597MCL\u60a3\u8005\u7684III\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u4e2d\u56fd\u5f00\u5c55\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\u8bfa\u8bda\u5065\u534e\u6b63\u5728\u63a2\u7d22\u5965\u5e03\u66ff\u5c3c\u4e0e\u6297&nbsp;CD20 \u6297\u4f53\u5965\u59a5\u73e0\u5355\u6297&nbsp;(Gazyva) \u7684\u8054\u5408\u7597\u6cd5\uff0c\u7528\u4e8e\u6cbb\u7597&nbsp;B \u7ec6\u80de\u6dcb\u5df4\u7624\u3002<\/li>\n<\/ul>\n<p><b><u>\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5<\/u><\/b><\/p>\n<p>\u9664\u4e86\u4e0a\u8ff0\u66f4\u65b0\u7684\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597&nbsp;MS \u548c&nbsp;SLE\uff0c\u8bfa\u8bda\u5065\u534e\u8fd8\u5728\u63a2\u7d22\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u539f\u53d1\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08ITP\uff09\u548c\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\uff08NMOSD\uff09\u3002<\/p>\n<ul type=\"disc\">\n<li><b>ITP: <\/b>2022\u5e742\u6708\uff0c\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u539f\u53d1\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08&nbsp;ITP\uff09II\u671f\u4e34\u5e8a\u7814\u7a76\u5728\u4e2d\u56fd\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002 <\/li>\n<li><b>NMOSD: <\/b>2022\u5e741\u6708\uff0c\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u89c6\u795e\u7ecf\u810a\u9ad3\u708e\u8c31\u7cfb\u75be\u75c5\u5df2\u901a\u8fc7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u4e34\u5e8a\u7814\u7a76\u7528\u65b0\u836f\u5ba1\u8bc4\uff0c\u83b7\u6279\u5728\u4e2d\u56fd\u5f00\u5c55\u4e34\u5e8aII\u671f\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b>\u5176\u4ed6\u7ba1\u7ebf\u4eae\u70b9<\/b><\/p>\n<p><b>\u8840\u6db2\u7624<\/b><\/p>\n<ul type=\"disc\">\n<li><b>ICP-B02 (CM355)<\/b><b>\uff1a<\/b>\u8bfa\u8bda\u5065\u534e\u548c\u5eb7\u8bfa\u4e9a\u5171\u540c\u5f00\u53d1\u7684CD20xCD3 \u53cc\u7279\u5f02\u6027\u6297\u4f53\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u6dcb\u5df4\u7624\u3002\u5728\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\uff0cICP-B02\u8868\u73b0\u51fa\u66f4\u5f3a\u7684&nbsp;T\u7ec6\u80de\u4ecb\u5bfc\u7684\u80bf\u7624\u7ec6\u80de\u6740\u4f24&nbsp;(TDCC) \u6d3b\u6027\u548c\u66f4\u5c11\u7684\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u3002\u9996\u4f4d\u60a3\u8005\u4e8e&nbsp;2022 \u5e741\u6708\u5b8c\u6210\u7ed9\u836f\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>ICP-490<\/b><b>\uff1a<\/b>\u4e00\u79cd\u9ad8\u6548\u53e3\u670d\u751f\u7269\u53ef\u5229\u7528\u7684\u4e0b\u4e00\u4ee3&nbsp;CRBN \u8c03\u8282\u5242\uff0c\u53ef\u8c03\u8282\u514d\u75ab\u7cfb\u7edf\u548c\u5176\u4ed6\u751f\u7269\u9776\u6807\uff0c\u9884\u8ba1\u5c06\u4e8e2022\u5e74\u4e0a\u534a\u5e74\u63d0\u4ea4IND\u7533\u8bf7\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>ICP-248<\/b><b>\uff1a<\/b>\u4e00\u79cd\u65b0\u578b\u7684\u3001\u53e3\u670d\u7684B\u7ec6\u80de\u6dcb\u5df4\u76242\uff08BCL-2\uff09\u9009\u62e9\u6027\u6291\u5236\u5242\u3002ICP-248\u62df\u5355\u836f\u548c\u8054\u5408\u7528\u836f\u6cbb\u7597\u8840\u6db2\u80bf\u7624\uff0c\u9884\u8ba12022\u5e74\u4e0a\u534a\u5e74\u63d0\u4ea4IND\u7533\u8bf7\u3002<\/li>\n<\/ul>\n<p><b>\u5b9e\u4f53\u7624<\/b><\/p>\n<ul type=\"disc\">\n<li><b>ICP-189<\/b><b>\uff1a<\/b>\u65b0\u578b\u86cb\u767d\u916a\u6c28\u9178\u78f7\u9178\u9176SHP2\uff08Src Homology 2 domain containing protein tyrosine phosphatase\uff09\u53d8\u6784\u6291\u5236\u5242\uff0c\u53ef\u7528\u4f5c\u5355\u836f\u4ee5\u53ca\u548c\u5176\u4ed6\u6297\u80bf\u7624\u836f\u8054\u5408\u6cbb\u7597\u5b9e\u4f53\u7624\u30022021\u5e7410\u6708\u548c2021\u5e7411\u6708\uff0cICP-189\u5206\u522b\u5728\u4e2d\u56fd\u548c\u7f8e\u56fd\u83b7\u6279\u4e34\u5e8a\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>ICP-033<\/b><b>\uff1a<\/b>\u65b0\u578b\u591a\u9776\u70b9\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\uff08RTK\uff09\u6291\u5236\u5242\uff0c\u8ba1\u5212\u5355\u7528\u6216\/\u548c\u514d\u75ab\u7597\u6cd5\u53ca\u5176\u4ed6\u9776\u5411\u836f\u8054\u5408\u6cbb\u7597\u809d\u764c\u3001\u80be\u7ec6\u80de\u764c\u3001\u5927\u80a0\u764c\u53ca\u5176\u4ed6\u5b9e\u4f53\u80bf\u7624\u30022021\u5e746\u6708\uff0cICP-033\u5728\u4e2d\u56fd\u83b7\u6279\u4e34\u5e8a\uff0c\u76ee\u524d\u6b63\u5728\u5f00\u5c55I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>ICP-915<\/b><b>\uff1a<\/b>\u4e00\u79cd\u9488\u5bf9KRAS\u7684G12C\u7a81\u53d8\u5f62\u5f0f\u7684\u9ad8\u9009\u62e9\u6027\u5c0f\u5206\u5b50\u6291\u5236\u5242\uff0c\u5c06\u4f1a\u8054\u5408ICP-189\u6cbb\u7597\u5b9e\u4f53\u7624\u3002<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li><b>ICP-B03<\/b><b>\uff1a<\/b>\u53ef\u5728\u80bf\u7624\u9776\u5411\u91ca\u653e\u7684\u767d\u4ecb\u7d20IL-15\u7684\u524d\u836f\uff0c\u53ef\u4ee5\u9776\u5411\u548c\u6539\u53d8\u80bf\u7624\u5fae\u73af\u5883\u5185\u7684\u514d\u75ab\u7ec6\u80de\u3002IL-15 \u662f\u4e00\u79cd\u7ec6\u80de\u56e0\u5b50\uff0c\u53ef\u6fc0\u6d3b\u91cd\u8981\u7684\u6297\u80bf\u7624\u514d\u75ab\u7ec6\u80de\uff0c\u4f8b\u5982&nbsp;CD8+T \u7ec6\u80de\u548c\u81ea\u7136\u6740\u4f24\uff08NK\uff09&nbsp;\u7ec6\u80de\u3002<\/li>\n<\/ul>\n<p><b>\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5<\/b><\/p>\n<ul type=\"disc\">\n<li><b>ICP-488<\/b><b>\uff1a<\/b>\u5c5e\u4e8e\u9009\u62e9\u6027TYK2\uff08\u916a\u6c28\u9178\u6fc0\u91762\uff09\u53d8\u6784\u6291\u5236\u5242\uff0c\u4f5c\u7528\u4e8e\u53d1\u6325\u8c03\u8282\u4f5c\u7528\u7684TYK2 JH2\uff0c\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u94f6\u5c51\u75c5\u548c\u708e\u75c7\u6027\u80a0\u75c5&nbsp;(IBD) \u7b49\u708e\u75c7\u6027\u75be\u75c5\u30022022\u5e743\u6708\uff0c\u83b7\u6279\u5728\u4e2d\u56fd\u5f00\u5c55\u4e34\u5e8a\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b>\u5176\u4ed6\u516c\u53f8\u8fdb\u5c55<\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u878d\u8d44<br \/><\/b>2021\u5e742\u6708\uff0c\u9ad8\u74f4\u8d44\u672c\u8fde\u540c\u7ef4\u68a7\u8d44\u672c\u589e\u6301\u8bfa\u8bda\u5065\u534e\uff0c\u6ce8\u8d443.93\u4ebf\u7f8e\u5143\u3002<br \/>2021 \u5e74&nbsp;12 \u6708\u81f3&nbsp;2022 \u5e74&nbsp;1 \u6708\uff0c\u8bfa\u8bda\u5065\u534e\u4e24\u540d\u5927\u80a1\u4e1c\u901a\u8fc7\u573a\u5185\u4ea4\u6613\u5171\u8d2d\u4e70\u672c\u516c\u53f8\u7ea6&nbsp;1,300 \u4e07\u80a1\u80a1\u4efd\u3002<br \/>2021\u5e749\u6708\uff0c\u8bfa\u8bda\u5065\u534e\u5411\u4e0a\u6d77\u8bc1\u5238\u4ea4\u6613\u6240\u63d0\u4ea4\u7684\u79d1\u521b\u677f\u4e0a\u5e02\u7533\u8bf7\u83b7\u53d7\u7406\u3002 <\/li>\n<li><b>\u751f\u4ea7\u5efa\u8bbe<br \/><\/b><b>\u5e7f\u5dde\uff1a<\/b>\u8bfa\u8bda\u5065\u534e\u5e7f\u5dde\u751f\u4ea7\u57fa\u57305\u4e07\u5e73\u65b9\u7c73\u7684\u4e00\u671f\u9879\u76ee\u4e8e2020\u5e74\u5e74\u5e95\u5b8c\u5de5\u3002\u4e00\u671f\u9879\u76ee\u5df2\u7ecf\u83b7\u5f97\u751f\u4ea7\u8bb8\u53ef\u8bc1\u3002\u76ee\u524d\u5df2\u5b8c\u6210\u5965\u5e03\u66ff\u5c3c\u6280\u672f\u8f6c\u79fb\u3002<br \/><b>\u5317\u4eac\uff1a<\/b>2021\u5e74\u5e74\u5e95\uff0c\u8bfa\u8bda\u5065\u534e\u5728\u516c\u53f8\u603b\u90e8\u9644\u8fd1\u7684\u5317\u4eac\u751f\u547d\u79d1\u5b66\u56ed\u83b7\u5f97\u4e00\u57577\u4e07\u591a\u5e73\u65b9\u7c73\u7684\u571f\u5730\uff0c\u7528\u4e8e\u5efa\u8bbe\u7814\u53d1\u4e2d\u5fc3\u548c\u5927\u5206\u5b50\u751f\u4ea7\u8bbe\u65bd\u3002\u76ee\u524d\u5df2\u7ecf\u5b8c\u6210\u6982\u5ff5\u8bbe\u8ba1\uff0c\u9884\u8ba12025\u5e74\u5b8c\u6210\u5efa\u8bbe\u3002 <\/li>\n<li><b>\u4eba\u624d<br \/><\/b>2021\u5e74\u4e0a\u534a\u5e74\uff0c\u8bfa\u8bda\u5065\u534e\u5206\u522b\u4efb\u547d\u5f20\u5411\u9633\u535a\u58eb\u548c\u6b27\u9633\u96ea\u677e\u535a\u58eb\u62c5\u4efb\u516c\u53f8\u9996\u5e2d\u533b\u5b66\u5b98\u548c\u751f\u7269\u5b66\u526f\u603b\u88c1\u3002<br \/>2021\u5e74\u4e0b\u534a\u5e74\uff0c\u8bfa\u8bda\u5065\u534e\u5206\u522b\u4efb\u547d\u9ad8\u6960\u5148\u751f\u548c\u738b\u4fca\u82cf\u5973\u58eb\u62c5\u4efb\u516c\u53f8\u9996\u5e2d\u8fd0\u8425\u5b98\u548c\u603b\u6cd5\u52a1\u987e\u95ee\u3002<\/li>\n<\/ul>\n<p>\u201c\u5c55\u671b2022\u5e74\uff0c\u6211\u4eec\u5c06\u7ee7\u7eed\u5728\u5404\u4e2a\u9886\u57df\u52aa\u529b\u594b\u8fdb\uff1a\u592f\u5b9e\u6211\u4eec\u7684\u7814\u53d1\u5b9e\u529b\uff0c\u52a0\u5feb\u63a8\u8fdb\u5404\u9879\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4e0d\u65ad\u63d0\u5347\u5546\u4e1a\u5316\u80fd\u529b\uff0c\u5145\u5206\u6316\u6398\u56fd\u9645\u5316\u4e1a\u52a1\u62d3\u5c55\u673a\u4f1a\u2026\u2026\u63a8\u52a8\u6211\u4eec\u7684\u53d1\u5c55\u66f4\u4e0a\u4e00\u4e2a\u65b0\u53f0\u9636\uff0c\u201d\u5d14\u9701\u677e\u535a\u58eb\u8bf4\u3002<\/p>\n<p>\u60f3\u8981\u4e86\u89e3\u8bfa\u8bda\u5065\u534e2021\u5e74\u5168\u5e74\u4e1a\u7ee9\u62a5\u544a\u8d22\u52a1\u6570\u636e\uff0c\u656c\u8bf7\u767b\u5f55<a target=\"_blank\" href=\"https:\/\/cn.innocarepharma.com\/en\/investor-relations\/\" rel=\"nofollow noopener\">https:\/\/cn.innocarepharma.com\/en\/investor-relations\/<\/a>&nbsp;&nbsp;&nbsp;\u8fdb\u884c\u67e5\u8be2\u3002<\/p>\n<p><b>\u7535\u8bdd\u4f1a\u8bae\u4fe1\u606f<\/b><\/p>\n<p>\u8bfa\u8bda\u5065\u534e\u5c06\u4e8e\u5317\u4eac\u65f6\u95f42022\u5e743\u670823\u65e5\u65e9\u4e0a9\u70b9\u53ec\u5f002021\u5e74\u4e1a\u7ee9\u7535\u8bdd\u4f1a\u8bae\u3002\u5982\u8981\u53c2\u52a0\u7535\u8bdd\u4f1a\u8bae\uff0c\u9700\u63d0\u524d\u6ce8\u518c\u3002\u8be6\u60c5\u5982\u4e0b\uff1a<\/p>\n<p>\u6ce8\u518c\u94fe\u63a5\uff1a<a target=\"_blank\" href=\"https:\/\/goldmansachs.zoom.us\/webinar\/register\/WN_JKhYhUVYS1W8HrlfBjzWsg\" rel=\"nofollow noopener\">https:\/\/goldmansachs.zoom.us\/webinar\/register\/WN_JKhYhUVYS1W8HrlfBjzWsg<\/a>&nbsp;<\/p>\n<p>\u4f1a\u8bae\u8bed\u8a00\u4e3a\u4e2d\u6587\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u62a5\u9053\u542b\u6709\u4e00\u4e9b\u524d\u77bb\u6027\u58f0\u660e\u7684\u62ab\u9732\u3002\u9664\u5bf9\u4e8b\u5b9e\u7684\u9648\u8ff0\u4ee5\u5916\uff0c\u6240\u6709\u5176\u4ed6\u58f0\u660e\u53ef\u88ab\u770b\u4f5c\u662f\u524d\u77bb\u6027\u58f0\u660e\uff0c\u5373\u5173\u4e8e\u6211\u4eec\u6216\u8005\u6211\u4eec\u7684\u7ba1\u7406\u90e8\u95e8\u6253\u7b97\u3001\u671f\u671b\u3001\u8ba1\u5212\u3001\u76f8\u4fe1\u6216\u8005\u9884\u671f\u5c06\u4f1a\u6216\u8005\u53ef\u80fd\u4f1a\u5728\u672a\u6765\u53d1\u751f\u7684\u884c\u4e3a\u3001\u4e8b\u4ef6\u6216\u8005\u53d1\u5c55\u6240\u505a\u51fa\u7684\u58f0\u660e\u3002\u6b64\u7c7b\u58f0\u660e\u662f\u6211\u4eec\u7684\u7ba1\u7406\u90e8\u95e8\u6839\u636e\u5176\u7ecf\u9a8c\u548c\u5bf9\u5386\u53f2\u8d8b\u52bf\u3001\u5f53\u524d\u6761\u4ef6\u3001\u9884\u671f\u672a\u6765\u53d1\u5c55\u548c\u5176\u4ed6\u76f8\u5173\u56e0\u7d20\u7684\u8ba4\u77e5\uff0c\u505a\u51fa\u7684\u5047\u8bbe\u4e0e\u4f30\u8ba1\u3002\u8be5\u524d\u77bb\u6027\u58f0\u660e\u5e76\u4e0d\u80fd\u4fdd\u8bc1\u672a\u6765\u7684\u4e1a\u7ee9\uff0c\u5b9e\u9645\u7684\u7ed3\u679c\uff0c\u53d1\u5c55\u548c\u4e1a\u52a1\u51b3\u7b56\u53ef\u80fd\u4e0e\u8be5\u524d\u77bb\u6027\u58f0\u660e\u7684\u8bbe\u60f3\u4e0d\u7b26\u3002\u6211\u4eec\u7684\u524d\u77bb\u6027\u58f0\u660e\u540c\u6837\u53d7\u5230\u5927\u91cf\u7684\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u56e0\u7d20\u7684\u5236\u7ea6\uff0c\u8fd9\u53ef\u80fd\u4f1a\u5f71\u54cd\u6211\u4eec\u7684\u8fd1\u671f\u4ee5\u53ca\u957f\u671f\u7684\u4e1a\u7ee9\u8868\u73b0\u3002<\/p>\n<p><b>\u5173\u4e8e\u8bfa\u8bda\u5065\u534e<\/b><\/p>\n<p>\u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u662f\u4e00\u5bb6\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u751f\u7269\u533b\u836f\u9ad8\u79d1\u6280\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u6cbb\u7597\u9886\u57df\u7684\u4e00\u7c7b\u65b0\u836f\u7814\u5236\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u6dcb\u5df4\u7624\u3001\u5b9e\u4f53\u7624\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u73b0\u6709\u591a\u4e2a\u65b0\u836f\u4ea7\u54c1\u5904\u4e8e\u5546\u4e1a\u5316\u3001\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u7814\u53d1\u9636\u6bb5\u3002\u516c\u53f8\u5728\u5317\u4eac\u3001\u5357\u4eac\u3001\u4e0a\u6d77\u3001\u5e7f\u5dde\u3001\u9999\u6e2f\u3001\u7f8e\u56fd\u65b0\u6cfd\u897f\u548c\u6ce2\u58eb\u987f\u5747\u8bbe\u6709\u5206\u652f\u673a\u6784\u3002<\/p>\n<p>\u76f8\u5173\u94fe\u63a5\uff1a<a target=\"_blank\" href=\"https:\/\/cn.innocarepharma.com\/cn\/\" rel=\"nofollow noopener\">https:\/\/cn.innocarepharma.com\/cn\/<\/a> <\/p>\n<div class=\"prntal\">\n<table id=\"convertedTablee9c2\" cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prnsbt0 prnsbr0 prnbcc prnsbb0 prnsbl0\">\n<tbody>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u8054\u7cfb\u4eba<\/b><\/span><\/p>\n<\/td>\n<td class=\"prngen2\"><\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u5a92\u4f53<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/b><\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u6295\u8d44\u8005<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u9646\u6625\u534e&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/span><\/p>\n<\/td>\n<td class=\"prngen2\"><\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">86-10-66609879&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">86-10-66609999<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:chunhua.lu@innocarepharma.com\" class=\"prnews_a\" rel=\"nofollow noopener\">chunhua.lu@innocarepharma.com<\/a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:ir@innocarepharma.com\" class=\"prnews_a\" rel=\"nofollow noopener\">ir@innocarepharma.com<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5317\u4eac2022\u5e743\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u4eca\u65e5\u53d1\u5e03\u622a\u81f32021\u5e7412\u670831\u65e5\u76842021\u5e74\u4e1a\u7ee9\u62a5\u544a\u548c\u516c\u53f8\u8fdb\u5c55\u3002 \u8bfa\u8bda\u5065\u534e\u8054\u5408\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5d14\u9701\u677e\u535a\u58eb\u8bf4\uff1a\u201c\u5f88\u9ad8\u5174\u5728\u6211\u4eec\u6e2f\u4ea4\u6240\u4e0a\u5e02\u4e24\u5468\u5e74\u4e4b\u9645\u53d1\u5e03\u516c\u53f82021\u5e74\u4e1a\u7ee9\u62a5\u544a\u30022021\u5e74\u662f\u4e0d\u5e73\u51e1\u7684\u4e00\u5e74\u3002\u6211\u4eec\u514b\u670d\u5404\u79cd\u56f0\u96be\u548c\u6311\u6218\uff0c\u5b9e\u73b0\u516c\u53f8\u53d1\u5c55\u5386\u53f2\u4e0a\u591a\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\u3002\u6211\u4eec\u5728\u5546\u4e1a\u5316\u5143\u5e74\u53d6\u5f97\u4ee4\u4eba\u6ee1\u610f\u7684\u6210\u7ee9\uff0c\u5965\u5e03\u66ff\u5c3c2021\u5e74\u5e95\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u5c06\u60e0\u53ca\u66f4\u591a\u60a3\u8005\uff1b\u6211\u4eec\u5728\u56fd\u9645\u5316\u8fdb\u5c55\u65b9\u9762\u53d6\u5f97\u91cd\u5927\u7a81\u7834\uff0c\u4e0e\u6e24\u5065\u548cIncyte\u516c\u53f8\u5206\u522b\u8fbe\u6210license-out\u548clicense-in\u7684\u91cd\u8981\u5408\u4f5c\uff1b\u6211\u4eec\u5728\u521b\u65b0\u9886\u57df\u6301\u7eed\u6df1\u8015\uff0c\u540c\u65f6\u4e0d\u65ad\u63a8\u8fdb\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e0c\u671b\u66f4\u591a\u5728\u7814\u521b\u65b0\u836f\u65e9\u65e5\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u2026\u2026\u201d \u4e3b\u8981\u8d22\u52a1\u4e1a\u7ee9\u6458\u8981 \u516c\u53f8\u6536\u5165\u4ece2020\u5e74\u7684140\u4e07\u5143\u5927\u5e45\u4e0a\u6da8\u81f32021\u5e74\u768410.43\u4ebf\u5143\uff0c\u4e3b\u8981\u5f97\u76ca\u4e8e\u5965\u5e03\u66ff\u5c3c\u7684\u9500\u552e\u6536\u5165\u548c\u6e24\u5065\u7684\u9996\u4ed8\u6b3e\u3002 \u7814\u53d1\u8d39\u7528\u4ece2020\u5e74\u76844.028\u4ebf\u5143\u589e\u81f32021\u5e74\u76847.216\u4ebf\u5143\uff0c\u4e3b\u8981\u662f\u589e\u52a0\u4e86license-in tafasitamab\u7684\u9996\u4ed8\u6b3e\u7b49\u3002 \u516c\u53f8\u73b0\u91d1\u548c\u73b0\u91d1\u7b49\u4ef7\u7269\u4ece2020\u5e74\u5e74\u5e95\u768439.696\u4ebf\u5143\u589e\u81f32021\u5e74\u5e74\u5e95\u768465.505\u4ebf\u5143\u3002 \u516c\u53f8\u4e8f\u635f\u5728\u62a5\u544a\u671f\u5185\u540c\u6bd4\u5927\u5e45\u4e0b\u964d\uff0c\u75312020\u5e74\u76843.919\u4ebf\u5143\u51cf\u5c11\u81f32021\u5e74\u76846670\u4e07\u5143\uff0c\u4e3b\u8981\u662f\u6e90\u4e8e\u6536\u5165\u589e\u52a0\u3002 \uff08\u6ce8\uff1a\u8d27\u5e01\u4e3a\u4eba\u6c11\u5e01\uff0c\u8bfa\u8bda\u5065\u534e\u8d22\u52a1\u5e74\u5ea6\u6307\u7684\u662f\u67d0\u4e00\u5e74\u76841\u67081\u65e5\u523012\u670831\u65e5\u3002\uff09 \u5173\u952e\u4eae\u70b9\u548c\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6 \u5e03\u9c81\u987f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5242\u5965\u5e03\u66ff\u5c3c \u5546\u4e1a\u5316\u8fdb\u5c55 \u8bfa\u8bda\u5065\u534e2021\u5e741\u6708\u4e2d\u5f00\u51fa\u9996\u6b3e\u5546\u4e1a\u5316\u4ea7\u54c1\u5965\u5e03\u66ff\u5c3c\u7684\u5168\u56fd\u9996\u65b9\u3002\u8bfa\u8bda\u5065\u534e\u5df2\u5efa\u7acb250\u540d\u7ecf\u9a8c\u4e30\u5bcc\u7684\u5546\u4e1a\u5316\u56e2\u961f\u3002\u622a\u81f32021\u5e7412\u670831\u65e5\uff0c\u5df2\u7ecf\u8fc5\u901f\u8986\u76d6260\u591a\u4e2a\u57ce\u5e02\u76841000\u591a\u5bb6\u533b\u9662\uff0c\u5b9e\u73b02.41\u4ebf\u5143\u4eba\u6c11\u5e01\u7684\u603b\u9500\u552e\uff08Gross Revenue\uff09\u3002 2021\u5e7412\u6708\uff0c\u5965\u5e03\u66ff\u5c3c\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\uff0c\u5c06\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u3002 \u5546\u52a1\u62d3\u5c55 \u8bfa\u8bda\u5065\u534e\u4e0e\u6e24\u5065\u5c31\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u591a\u53d1\u6027\u786c\u5316\uff08MS\uff09\u8fbe\u6210\u8bb8\u53ef\u53ca\u5408\u4f5c\u534f\u8bae\uff0c\u8bfa\u8bda\u5065\u534e\u56e0\u6b64\u4e8e2021\u5e749\u6708\u6536\u5230\u6e24\u50651.25\u4ebf\u7f8e\u5143\u9996\u4ed8\u6b3e\u3002\u6b64\u5916\uff0c\u5728\u8fbe\u5230\u5408\u4f5c\u7ea6\u5b9a\u7684\u5f00\u53d1\u91cc\u7a0b\u7891\u3001\u5546\u4e1a\u5316\u91cc\u7a0b\u7891\u65f6\uff0c\u8bfa\u8bda\u5065\u534e\u6709\u8d44\u683c\u83b7\u5f97\u81f3\u591a8.125\u4ebf\u7f8e\u5143\u7684\u6f5c\u5728\u4e34\u5e8a\u5f00\u53d1\u91cc\u7a0b\u7891\u548c\u5546\u4e1a\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u8bfa\u8bda\u5065\u534e\u8fd8\u5c06\u6709\u8d44\u683c\u83b7\u5f97\u6f5c\u5728\u672a\u6765\u51c0\u9500\u552e\u989d\u767e\u5206\u4e4b\u5341\u51e0\u8303\u56f4\u5185\u4ece\u4f4e\u81f3\u9ad8\u7684\u5206\u5c42\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u3002 \u76ee\u524d\uff0c\u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u591a\u53d1\u6027\u786c\u5316\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u7f8e\u56fd\u3001\u6b27\u6d32\u548c\u4e2d\u56fd\u5f00\u5c55\u3002 \u7814\u53d1\u8fdb\u5c55 \u5965\u5e03\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09 \u5965\u5e03\u66ff\u5c3c\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e8e2021\u5e74\u5e74\u5e95\u5b8c\u6210\u3002 \u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u8f7b\u4e2d\u5ea6\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u60a3\u8005\u53e3\u670d\u5965\u5e03\u66ff\u5c3c\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u826f\u597d\u3002\u5728\u6240\u6709\u63a5\u53d7\u6cbb\u7597\u53ef\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u7597\u6548\u5448\u5242\u91cf\u4f9d\u8d56\u6027\u3002\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5b89\u6170\u5242\u3001\u5965\u5e03\u66ff\u5c3c50\u6beb\u514b\u300180\u6beb\u514b\u548c100\u6beb\u514b\uff0c\u7b2c12\u5468SRI-4\uff08SLE\u5e94\u7b54\u8005\u6307\u65704\uff09\u7684\u5e94\u7b54\u7387\u5206\u522b\u4e3a37.5%\u300150.0%\u300161.5%\u548c64.3%\u3002 \u5728SLE\u60a3\u8005\u4e2d\uff0c\u5965\u5e03\u66ff\u5c3c\u53ef\u964d\u4f4e\u86cb\u767d\u5c3f\u6c34\u5e73\uff0c\u6539\u5584\u514d\u75ab\u6807\u8bb0\u7269\uff0c\u5305\u62ec\u964d\u4f4e\u514d\u75ab\u7403\u86cb\u767dG\uff0c\u589e\u52a0\u8865\u4f53C3\u548cC4\u3002 \u8bfa\u8bda\u5065\u534e\u5c06\u7ee7\u7eed\u63a8\u8fdb\u5965\u5e03\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u4e34\u5e8a\u7814\u7a76\u3002 \u5965\u5e03\u66ff\u5c3c\u4e00\u7ebf\u6cbb\u7597\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09MCD \u4e9a\u578b \u8bfa\u8bda\u5065\u534e\u6b63\u5728\u5f00\u5c55\u4e00\u9879\u8bc4\u4ef7\u5965\u5e03\u66ff\u5c3c\u8054\u5408R-CHOP \u65b9\u6848\u5bf9\u6bd4\u5b89\u6170\u5242\u8054\u5408R-CHOP \u65b9\u6848\u6cbb\u7597\u4e00\u7ebfMCD \u4e9a\u578b\u5f25\u6f2b\u6027\u5927B \u7ec6\u80de\u6dcb\u5df4\u7624\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u968f\u673a\u3001\u53cc\u76f2\u3001\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3III \u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5c06\u4e3a\u4e00\u7ebfDLBCL\u60a3\u8005\u63d0\u4f9b\u66f4\u597d\u7684\u6cbb\u7597\u9009\u62e9\u3002 ICP-B04 (Tafasitamab) 2021\u5e748\u6708\uff0c\u8bfa\u8bda\u5065\u534e\u548cIncyte\u516c\u53f8\u5c31\u4e00\u6b3e\u9776\u5411CD19\u7684Fc\u7ed3\u6784\u57df\u4f18\u5316\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53tafasitamab\u5728\u5927\u4e2d\u534e\u533a\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7b7e\u8ba2\u4e86\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\u3002Tafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u5df2\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u548c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7684\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6027\u5f25\u6f2b\u6027\u5927&nbsp;B \u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u60a3\u8005\u3002 \u8bfa\u8bda\u5065\u534e\u4e0eIncyte\u7684\u6218\u7565\u5408\u4f5c\u5c06\u4e3a\u63a2\u7d22tafasitamab\u548c\u5965\u5e03\u66ff\u5c3c\u4ee5\u53ca\u8bfa\u8bda\u5065\u534e\u5176\u4ed6\u7ba1\u7ebf\u8054\u5408\u6cbb\u7597B\u7ec6\u80de\u6076\u6027\u80bf\u7624\u63d0\u4f9b\u4e86\u826f\u597d\u7684\u673a\u4f1a\uff0c\u4e5f\u5c06\u589e\u5f3a\u8bfa\u8bda\u5065\u534e\u5728\u8840\u6db2\u7624\u548c\u5b9e\u4f53\u7624\u9886\u57df\u7684\u5b9e\u529b\u3002 Tafasitamab\u8054\u5408\u6765\u90a3\u5ea6\u80fa\u5df2\u83b7\u5f97\u6d77\u5357\u7701\u536b\u5065\u59d4\u548c\u836f\u76d1\u5c40\u6279\u51c6\uff0c\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u6cbb\u7597\u7b26\u5408\u6761\u4ef6\u7684DLBCL\u60a3\u8005\u3002 ICP-192 (Gunagratinib) Gunagratinib\u76ee\u524d\u6b63\u5728\u4e2d\u56fd\u548c\u7f8e\u56fd\u8fdb\u884c\u591a\u4e2aI\/II\u671f\u4e34\u5e8a\u7814\u7a76\u3002\u5728\u4e2d\u56fd\uff0c\u5728I\/II\u671f\u8bd5\u9a8c\u7684\u5242\u91cf\u9012\u589e\u90e8\u5206\uff0c\u57282\u523026\u6beb\u514b\u5242\u91cf\u8303\u56f4\u5185\u7684\u6240\u6709\u5242\u91cf\u7ec4\u4e2d\uff0c\u5747\u8bc1\u660e\u4e86gunagratinib\u7684\u826f\u597d\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u672a\u89c2\u5bdf\u5230\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\uff08DLT\uff09\u3002 \u5934\u9888\u764c\u5728\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\u4e2d\uff0c\u5728FGF\/FGFR\u57fa\u56e0\u5f02\u5e38\u7684\u5934\u9888\u764c\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230gunagratinib\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002\u81f3\u5c11\u5b8c\u6210\u4e00\u6b21\u80bf\u7624\u8bc4\u4f30\u76849\u4f8bFGF\/FGFR\u57fa\u56e0\u5f02\u5e38\u60a3\u8005\u4e2d\uff0c\u603b\u7f13\u89e3\u7387\uff08ORR\uff09\u4e3a33.3%\u30022022\u5e74\u5e74\u521d\uff0c\u8bfa\u8bda\u5065\u534e\u542f\u52a8\u4e86\u4e00\u9879\u5305\u62ecFGF\/FGFR\u57fa\u56e0\u5f02\u5e38\u7684\u5934\u9888\u764c\u5728\u5185\u7684\u5b9e\u4f53\u7624\u7bee\u5f0f\u8bd5\u9a8c\u3002 \u80c6\u7ba1\u764c\u5728II\u671f\u8bd5\u9a8c\u4e2d\uff0c20\u6beb\u514b&nbsp;gunagratinib\u5bf9\u80c6\u7ba1\u764c\u60a3\u8005\u663e\u793a\u51fa\u521d\u6b65\u6709\u6548\u6027\u3002\u622a\u81f32022\u5e741\u670813\u65e5\uff0c\u5728\u81f3\u5c11\u5b8c\u6210\u4e00\u9879\u80bf\u7624\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\uff0cORR\u4e3a60%\uff0c\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u4e3a100%\u3002 \u56fd\u9645\u8fdb\u5c552021\u5e746\u6708\uff0cgunagratinib\u83b7\u5f97\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597\u80c6\u7ba1\u764c\u3002\u8bfa\u8bda\u5065\u534e\u6b63\u5728\u7f8e\u56fd\u548c\u6fb3\u5927\u5229\u4e9a\u5f00\u5c55\u9488\u5bf9\u80c6\u7ba1\u764c\u548c\u5934\u9888\u764c\u5242\u91cf\u9012\u589e\u7684I\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002 ICP-723 \u622a\u81f3&nbsp;2022 \u5e74&nbsp;2 \u6708&nbsp;11 \u65e5\uff0c\u5728&nbsp;I \u671f\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\u4e2d\uff0c\u5171\u6709&nbsp;17 \u4f8b\u60a3\u8005\u63a5\u53d7\u4e86&nbsp;ICP-723 \u7684\u6cbb\u7597\uff0c\u5242\u91cf\u4e3a&nbsp;1\u6beb\u514b\u81f3&nbsp;8\u6beb\u514b\uff0c\u6bcf\u5929\u4e00\u6b21\u3002\u5b89\u5168\u6027\u826f\u597d\uff0c\u6ca1\u6709\u89c2\u5bdf\u5230&nbsp;DLT\u300217\u4f8b\u60a3\u8005\u4e2d\uff0c5\u4f8b\u60a3\u8005\u786e\u8ba4\u4e3aNTRK\u57fa\u56e0\u878d\u5408\u9633\u6027\uff0cORR\u4e3a80%\uff084\u4f8bPR\uff09\uff0cDCR\u4e3a100%\u3002\u57284\u6beb\u514b\u53ca\u4ee5\u4e0a\u5242\u91cf\u7ec4\u4e2d\uff0cORR\u4e3a100%\u3002&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2022032307050065632\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":8278,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-65632","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/65632","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=65632"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/65632\/revisions"}],"predecessor-version":[{"id":65633,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/65632\/revisions\/65633"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/8278"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=65632"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=65632"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=65632"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}