{"id":65591,"date":"2022-03-23T10:08:00","date_gmt":"2022-03-23T03:08:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022032310080065591"},"modified":"2022-03-23T17:59:20","modified_gmt":"2022-03-23T09:59:20","slug":"%e7%a7%91%e6%b5%8e%e8%8d%af%e4%b8%9a%e5%8f%91%e5%b8%832021%e5%b9%b4%e5%ba%a6%e4%b8%9a%e7%bb%a9%e6%8a%a5%e5%91%8a%ef%bc%9a%e6%b7%b1%e8%80%95car-t%ef%bc%8c%e6%8c%81%e7%bb%ad%e5%88%9b%e6%96%b0","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022032310080065591","title":{"rendered":"\u79d1\u6d4e\u836f\u4e1a\u53d1\u5e032021\u5e74\u5ea6\u4e1a\u7ee9\u62a5\u544a\uff1a\u6df1\u8015CAR-T\uff0c\u6301\u7eed\u521b\u65b0"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/Logo-313.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><p>\u4e0a\u6d772022\u5e743\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u79d1\u6d4e\u836f\u4e1a\uff08\u80a1\u7968\u4ee3\u7801\uff1a2171.HK\uff09\uff0c\u4e00\u5bb6\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u521b\u65b0CAR-T\u7ec6\u80de\u7597\u6cd5\u516c\u53f8\uff0c\u53d1\u5e032021\u5e74\u5ea6\u4e1a\u7ee9\u62a5\u544a\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder7764\">\n<\/p><\/div>\n<p><b>\u4e1a\u7ee9\u4eae\u70b9\u901f\u89c8<\/b><\/p>\n<ul type=\"disc\">\n<li>CT053\u5b8c\u6210\u4e2d\u56fd\u5173\u952eII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5165\u7ec4\uff0c\u8ba1\u5212\u4e8e2022\u5e74\u4e0a\u534a\u5e74\u63d0\u4ea4NDA <\/li>\n<li>CT053\u542f\u52a8\u5317\u7f8e\u5173\u952e2\u671f\u4e34\u5e8a\u8bd5\u9a8c <\/li>\n<li>CT041\u542f\u52a8\u4e2d\u56fd\u786e\u8bc1\u6027\u2161\u671f\u4e34\u5e8a\u8bd5\u9a8c <\/li>\n<li>CT041\u83b7\u5f97EMA\u4f18\u5148\u836f\u7269\uff08PRIME\uff09\u8d44\u683c\u3001FDA\u518d\u751f\u533b\u5b66\u5148\u8fdb\u7597\u6cd5\uff08RMAT\uff09\u8d44\u683c <\/li>\n<li>CT0590\u3001CT0180\u3001CT0181\u7b49\u521b\u65b0CAR-T\u5019\u9009\u4ea7\u54c1\u8fdb\u5165\u4e34\u5e8a\u9636\u6bb5 <\/li>\n<li>LADAR<sup>&reg;<\/sup>\u6280\u672f\u5e73\u53f0\u9996\u6b21\u4eae\u76f8 <\/li>\n<li>\u7f8e\u56fd\u5de5\u5382\u5b8c\u6210\u5efa\u8bbe\uff0c\u542f\u52a8\u8fd0\u8425<\/li>\n<\/ul>\n<p><b>\u79d1\u6d4e\u836f\u4e1a\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u3001\u9996\u5e2d\u6267\u884c\u5b98\u3001\u9996\u5e2d\u79d1\u5b66\u5b98\u674e\u5b97\u6d77\u535a\u58eb\u8868\u793a<\/b>\uff1a<br \/>\u8fd9\u662f\u79d1\u6d4e\u836f\u4e1a\u7ee72021\u5e746\u670818\u65e5\u4e8e\u6e2f\u4ea4\u6240\u4e0a\u5e02\u540e\u7684\u7b2c\u4e00\u4e2a\u5e74\u5ea6\u4e1a\u7ee9\u62a5\u544a\u3002\u5728\u8fc7\u53bb\u7684\u4e00\u5e74\u91cc\uff0c\u79d1\u6d4e\u836f\u4e1a\u5728\u5168\u793e\u4f1a\u5404\u65b9\u7684\u9f0e\u529b\u652f\u6301\u4e0b\u53d6\u5f97\u4e86\u591a\u9879\u91cd\u8981\u8fdb\u5c55\uff0c\u7279\u522b\u662f\u5728\u7ba1\u7ebf\u63a8\u8fdb\u3001\u6280\u672f\u521b\u65b0\u3001\u4ea7\u80fd\u6269\u5f20\u3001\u5bf9\u5916\u5408\u4f5c\u3001\u4eba\u624d\u6269\u5145\u7b49\u65b9\u9762\u53d6\u5f97\u4e86\u4e0d\u4fd7\u7684\u6210\u7ee9\u3002\u6211\u4eec\u5c06\u59cb\u7ec8\u79c9\u627f&quot;\u79d1\u521b\u6d4e\u4e16&quot;\u7684\u613f\u666f\uff0c\u6301\u7eed\u63a8\u8fdb\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5f00\u53d1\u81ea\u4e3b\u521b\u65b0\u6280\u672f\uff0c\u592f\u5b9e\u5168\u7403\u5316\u6218\u7565\u5e03\u5c40\uff0c\u65e9\u65e5\u4e3a\u5168\u7403\u764c\u75c7\u60a3\u8005\u5e26\u6765\u521b\u65b0\u548c\u5dee\u5f02\u5316\u7684\u7ec6\u80de\u7597\u6cd5\uff0c\u540c\u65f6\u4e3a\u5e7f\u5927\u6295\u8d44\u8005\u548c\u793e\u4f1a\u516c\u4f17\u521b\u9020\u66f4\u591a\u4ef7\u503c\u3002<\/p>\n<p><b>\u4e00\u3001\u4ea7\u54c1\u7ba1\u7ebf\u53d1\u5c55\u8fc5\u901f\uff0c\u6838\u5fc3\u4ea7\u54c1\u6210\u7ee9\u4eae\u773c<\/b><\/p>\n<p><b>CT053<\/b><\/p>\n<p>CT053\u662f\u4e00\u79cd\u9488\u5bf9BCMA\u7684\u81ea\u4f53CAR-T\u7ec6\u80de\u6838\u5fc3\u5019\u9009\u4ea7\u54c1\uff0c\u88ab\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08R\/R MM\uff09\u3002\u5176\u878d\u5408\u4e86\u79d1\u6d4e\u8bbe\u8ba1\u7684\u5347\u7ea7\u7248CAR\u7ed3\u6784\uff0c\u5177\u6709\u8f83\u4f4e\u514d\u75ab\u539f\u6027\u548c\u8f83\u9ad8\u7a33\u5b9a\u6027\u7684\u5168\u4eba\u6297BCMA\u7279\u5f02\u6027\u5355\u94fe\u6297\u4f53\uff0c\u5728\u6ca1\u6709\u80bf\u7624\u76f8\u5173\u9776\u70b9\u7684\u60c5\u51b5\u4e0b\uff0c\u53ef\u964d\u4f4eCAR-T\u7ec6\u80de\u7684\u81ea\u52a8\u6fc0\u6d3b\u3002<\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\u5df2\u5b8c\u6210\u5728\u4e2d\u56fd\u8fdb\u884c\u7684\u5173\u952eII\u671f\u8bd5\u9a8c\uff08LUMMICAR STUDY 1\uff09\u7684\u60a3\u8005\u5165\u7ec4\u3002\u6b64\u5916\uff0c\u79d1\u6d4e\u836f\u4e1a\u5df2\u5f00\u59cb\u5728\u5317\u7f8e\u8fdb\u884c\u5173\u952e2\u671f\u4e34\u5e8a\u8bd5\u9a8c(LUMMICAR STUDY 2)\uff0c\u5e76\u4e8e2021\u5e748\u6708\u5728\u5173\u952e2\u671f\u8bd5\u9a8c\u4e2d\u6cbb\u7597\u4e86\u9996\u540d\u60a3\u8005\u3002\u7ecf\u4e0e\u7f8e\u56fdFDA\u6c9f\u901a\uff0c\u516c\u53f8\u5c06CT053\u7684\u95e8\u8bca\u7ed9\u836f\u52a0\u5165\u7f8e\u56fd\u4e34\u5e8a\u7814\u7a76\u4e2d\u3002<\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\u8ba1\u5212\u4e8e2022\u5e74\u4e0a\u534a\u5e74\u5411\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u63d0\u4ea4NDA\uff0c\u5e76\u8ba1\u5212\u4e8e2023\u5e74\u5411\u7f8e\u56fdFDA\u63d0\u4ea4BLA\u3002\u516c\u53f8\u4ea6\u8ba1\u5212\u8fdb\u884c\u5176\u4ed6\u4e34\u5e8a\u8bd5\u9a8c\u4ee5\u5f00\u53d1CT053\u4f5c\u4e3a\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684\u65e9\u7ebf\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<p>\u4e2d\u56fdI\/II\u671f\u7814\u7a76\uff08LUMMICAR STUDY 1\uff09\u7684\u8fdb\u5c55\u53caR\/R MM\u60a3\u8005\u7684\u9ad8\u5371\u56e0\u7d20\u7efc\u5408\u5206\u6790\u5df2\u4e8e2021\u5e74\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a\uff08ASH\uff09\u5e74\u4f1a\u4e0a\u4ee5\u6d77\u62a5\u5f62\u5f0f\u5448\u5217\u3002<\/p>\n<p><b>CT041<\/b><\/p>\n<p>CT041\u662f\u4e00\u79cd\u6f5c\u5728\u5168\u7403\u540c\u7c7b\u9996\u521b\u7684\u3001\u9776\u5411Claudin18.2\uff08CLDN18.2\uff09\u86cb\u767d\u7684\u81ea\u4f53CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\u3002CT041\u7528\u4e8e\u6cbb\u7597CLDN18.2\u9633\u6027\u5b9e\u4f53\u7624\uff0c\u4e3b\u8981\u6cbb\u7597\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\uff08GC\/GEJ\uff09\u53ca\u80f0\u817a\u764c\uff08PC\uff09\u3002\u79d1\u6d4e\u836f\u4e1a\u5df2\u5728\u4e2d\u56fd\u5f00\u5c55\u4e86\u7814\u7a76\u8005\u53d1\u8d77\u7684\u8bd5\u9a8c\u3001\u4e00\u9879\u9488\u5bf9\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u548c\u80f0\u817a\u764c\u7684Ib\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3001\u4e00\u9879\u9488\u5bf9\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u7684\u786e\u8bc1\u6027II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u53ca\u5728\u5317\u7f8e\u542f\u52a8\u4e86\u4e00\u9879\u9488\u5bf9\u665a\u671f\u80c3\u764c\u6216\u80f0\u817a\u764c\u76841b\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p>\u5728\u5317\u7f8e\uff0c\u79d1\u6d4e\u836f\u4e1a\u5df2\u542f\u52a8CT041-ST-02\u76841b\u671f\u8bd5\u9a8c\uff0c\u5e76\u4e8e2021\u5e747\u6708\u5b8c\u6210\u4e86\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/p>\n<p>CT041\u5148\u540e\u53d6\u5f97\u7f8e\u56fdFDA\u7684\u5b64\u513f\u836f\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\uff1b\u4ee5\u53caEMA\u7684\u5b64\u513f\u836f\u4ea7\u54c1\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u764c\u30022021\u5e7411\u6708\uff0cCT041\u83b7EMA\u6388\u4e88\u4f18\u5148\u836f\u7269\uff08PRIME\uff09\u8d44\u683c\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u764c\uff1b2022\u5e741\u6708\uff0cCT041\u83b7\u5f97FDA\u518d\u751f\u533b\u5b66\u5148\u8fdb\u7597\u6cd5\uff08RMAT\uff09\u8d44\u683c\u7528\u4e8e\u6cbb\u7597CLDN18.2\u9633\u6027\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u3002<\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\u8ba1\u5212\u4e8e2024\u5e74\u4e0a\u534a\u5e74\u5411\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u63d0\u4ea4NDA\uff0c\u5e76\u8ba1\u5212\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u5728\u5317\u7f8e\u542f\u52a82\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4e8e2024\u5e74\u5411\u7f8e\u56fdFDA\u63d0\u4ea4BLA\u3002<\/p>\n<p>CT041\u5728\u6b63\u5728\u8fdb\u884c\u7684\u7814\u7a76\u8005\u53d1\u8d77\u7684\u8bd5\u9a8c\u4e2d\u5c55\u73b0\u4e86\u826f\u597d\u7684\u7597\u6548\u53ca\u5b89\u5168\u6027\uff0c\u8be5\u8bd5\u9a8c\u8fdb\u5c55\u5df2\u4e8e2021\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\u5927\u4f1a\uff08ESMO\uff09\u4e0a\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u8fdb\u884c\u4e86\u5c55\u793a\u3002<\/p>\n<p><b>CT011<\/b><\/p>\n<p>CT011\u662f\u4e00\u79cd\u6f5c\u5728\u5168\u7403\u540c\u7c7b\u9996\u521b\u7684CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\uff08\u4eba\u6e90\u5316GPC3 CAR-T\uff09\uff0c\u5177\u6709\u6cbb\u7597\u809d\u7ec6\u80de\u764c\uff08HCC\uff09\u7684\u6982\u5ff5\u9a8c\u8bc1\u4e34\u5e8a\u6570\u636e\u3002\u516c\u53f8\u5df2\u5728\u4e2d\u56fd\u5b8c\u6210I\u671f\u8bd5\u9a8c\u60a3\u8005\u5165\u7ec4\u3002<\/p>\n<p><b>CT032<\/b><\/p>\n<p>CT032\u662f\u4e00\u79cd\u9776\u5411CD19\u7684\u4eba\u6e90\u5316\u81ea\u4f53CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\uff0c\u88ab\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08NHL\uff09\u3002\u516c\u53f8\u6b63\u5728\u4e2d\u56fd\u8fdb\u884cI\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p><b>AB011<\/b><\/p>\n<p>AB011\u662f\u4e00\u6b3e\u9776\u5411CLDN18.2\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\u5019\u9009\u4ea7\u54c1\uff0c\u88ab\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597CLDN18.2\u9633\u6027\u5b9e\u4f53\u7624\u30022021\u5e74\u7b2c\u4e8c\u5b63\u5ea6\uff0c\u516c\u53f8\u6536\u5230\u836f\u5ba1\u4e2d\u5fc3\u5173\u4e8e\u5728Ib\u671f\u8bd5\u9a8c\u65b0\u589eAB011\u8054\u5408\u5316\u7597\u961f\u5217\u7684\u8865\u5145\u7533\u8bf7\u6279\u51c6\uff0c\u5e76\u4e8e\u5176\u540e\u542f\u52a8AB011\u4e0e\u5316\u7597\u7684\u8054\u5408\u961f\u5217\u7814\u7a76\uff0c\u516c\u53f8\u73b0\u5df2\u5b8c\u6210\u2160\u671f\u5355\u836f\u5165\u7ec4\u5e76\u542f\u52a8\u8054\u5408\u5316\u7597\u3002<\/p>\n<p>\u516c\u53f8\u8ba1\u5212\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u5411\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u63d0\u4ea4\u54a8\u8be2\u7533\u8bf7\uff0c\u6c9f\u901a\u542f\u52a8\u540e\u7eed\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p><b>CT0180<\/b><\/p>\n<p>CT0180\u662f\u4e00\u79cd\u88ab\u8bbe\u8ba1\u4e3a\u8868\u8fbe\u9776\u5411GPC3\u6297\u4f53\u878d\u5408T\u7ec6\u80de\u53d7\u4f53\uff08aTCR\uff09\u7684\u878d\u5408\u86cb\u767d\u7684\u81ea\u4f53T\u7ec6\u80de\u4ea7\u54c1\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793a\uff0c\u5728\u5c0f\u9f20\u5f02\u79cd\u79fb\u690d\u6a21\u578b\u4e2d\uff0cCT0180\u53ef\u6709\u6548\u8bc6\u522b\u548c\u6740\u6b7bGPC3\u9633\u6027\u809d\u7ec6\u80de\u764c\u7ec6\u80de\u5e76\u5927\u5e45\u6291\u5236HCC\u80bf\u7624\u751f\u957f\uff0c\u4f53\u5185\u53ca\u4f53\u5916\u7684\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u4f4e\u4e8eGPC3 CAR-T\u7ec6\u80de\uff0c\u63d0\u5347\u4e86\u8fc7\u7ee7\u6027\u7ec6\u80de\u7597\u6cd5\u7684\u5b89\u5168\u6027\u53ca\u9002\u7528\u6027\u3002<\/p>\n<p><b>CT0181<\/b><\/p>\n<p>CT0181\u662f\u4e00\u79cd\u88ab\u8bbe\u8ba1\u4e3a\u91c7\u7528\u9776\u5411GPC3\u6297\u4f53\u878d\u5408T\u7ec6\u80de\u53d7\u4f53\u5171\u8868\u8fbeIL-7\u7ec6\u80de\u56e0\u5b50\u7684\u81ea\u4f53T\u7ec6\u80de\u4ea7\u54c1\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u8868\u660e\uff0c\u4e0eGPC3 CAR-T\u7ec6\u80de\u76f8\u6bd4\uff0cCT0181\u5728\u5177\u6709\u4f4e\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u7684\u5b9e\u4f53\u7624\u5f02\u79cd\u79fb\u690d\u7269\u4e2d\u663e\u793a\u51fa\u5353\u8d8a\u7684\u6297\u80bf\u7624\u529f\u6548\u3001T\u7ec6\u80de\u6301\u4e45\u6027\u53ca\u514d\u75ab\u8bb0\u5fc6\u3002<\/p>\n<p><b>KJ-C2111<\/b><b>\uff08<\/b><b>CT0590<\/b><b>\uff09<\/b><\/p>\n<p>CT0590\u662f\u4e00\u79cd\u5229\u7528THANK-uCAR<sup>&reg;<\/sup>\u6280\u672f\u9776\u5411BCMA\u7684\u540c\u79cd\u5f02\u4f53CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\u3002\u79d1\u6d4e\u836f\u4e1a\u6b63\u5728\u5f00\u53d1CT0590\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08R\/R MM\uff09\u3002\u516c\u53f8\u5df2\u7ecf\u542f\u52a8\u7814\u7a76\u8005\u53d1\u8d77\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bc4\u4f30CT0590\u6cbb\u7597R\/R MM\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002<\/p>\n<p>\u516c\u53f8\u5176\u4ed6\u5904\u4e8eIND\u7533\u62a5\u51c6\u5907\u6216\u4e34\u5e8a\u524d\u9636\u6bb5\u5019\u9009\u4ea7\u54c1\u5305\u62ec\uff1a&nbsp;KJ-C1807\uff08CT048\uff09\u3001KJ-C2112<a name=\"_Hlk98500275\" target=\"_blank\" href=\"https:\/\/prndl2-irisxe1.prnewswire.local\/ewebeditor\/\" rel=\"nofollow noopener\">\u3001<\/a>KJ-C2113\u53caKJ-C2114\u3002<\/p>\n<p><b>\u4e8c\u3001\u5927\u529b\u63a8\u8fdb\u521b\u65b0\u6280\u672f\uff0c\u89e3\u51b3\u884c\u4e1a\u4e3b\u8981\u6311\u6218<\/b><\/p>\n<p>\u5c3d\u7ba1\u5df2\u7ecf\u6709\u8840\u6db2\u7624CAR-T\u4ea7\u54c1\u83b7\u6279\uff0cCAR-T\u7597\u6cd5\u4ecd\u7136\u9762\u4e34\u8bf8\u591a\u6311\u6218\uff0c\u79d1\u6d4e\u836f\u4e1a\u81f4\u529b\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1\u521b\u65b0\u6280\u672f\u5e73\u53f0\uff0c\u4ee5\u5e94\u5bf9\u8be5\u7b49\u6311\u6218\uff0c\u4e3a\u5168\u7403\u764c\u75c7\u60a3\u8005\u751f\u4ea7\u66f4\u597d\u7684\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\uff0c\u516c\u53f8\u4e3b\u8981\u5173\u6ce8\u70b9\u6709\u4ee5\u4e0b\u56db\u4e2a\u65b9\u5411\uff1a<\/p>\n<ul type=\"disc\">\n<li>\u63d0\u9ad8\u5b9e\u4f53\u7624\u7597\u6548\uff1a\u5f00\u53d1CycloCAR<sup>&reg;<\/sup>\u7b49\u521b\u65b0\u6280\u672f\uff0c\u63d0\u9ad8CAR-T\u7ec6\u80de\u9488\u5bf9\u5b9e\u4f53\u7624\u7684\u7597\u6548\u3002CycloCAR<sup>&reg;<\/sup>\u662f\u4e0b\u4e00\u4ee3CAR-T\u6280\u672f\uff0c\u5176\u5171\u540c\u8868\u8fbe\u7ec6\u80de\u56e0\u5b50IL-7\u548c\u8d8b\u5316\u56e0\u5b50CCL21\uff0c\u5e76\u6709\u53ef\u80fd\u5177\u6709\u66f4\u9ad8\u7684\u4e34\u5e8a\u7597\u6548\uff0c\u4e14\u4e0d\u9700\u8981\u6e05\u6dcb\u9884\u5904\u7406\uff1b <\/li>\n<li>\u63d0\u9ad8\u5b89\u5168\u6027\uff1a\u5f00\u53d1\u521b\u65b0\u6280\u672f\uff0c\u6700\u5927\u7a0b\u5ea6\u51cf\u5c11\u5305\u62ec\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\uff08CRS\uff09\u3001\u795e\u7ecf\u6bd2\u6027\u53ca\u8131\u9776\u6bd2\u6027\u5728\u5185\u7684\u5b89\u5168\u95ee\u9898\uff1b <\/li>\n<li>\u6269\u5927\u60a3\u8005\u53ef\u53ca\u6027\uff1a\u63a8\u8fdb\u5dee\u5f02\u5316\u7684\u540c\u79cd\u5f02\u4f53THANK-uCAR<sup>&reg;<\/sup>\u6280\u672f\u4ee5\u964d\u4f4e\u6210\u672c\u53ca\u63d0\u9ad8\u53ef\u8d1f\u62c5\u6027\u3002THANK-uCAR<sup>&reg;<\/sup>\u6280\u672f\u6709\u671b\u514b\u670d\u73b0\u6709\u901a\u7528CAR-T\u7ec6\u80de\u4f4e\u6548\u6269\u589e\u53ca\u6301\u4e45\u6027\u4e0d\u9ad8\u7684\u95ee\u9898\uff1b <\/li>\n<li>\u63d0\u9ad8\u9776\u70b9\u53ef\u7528\u6027\uff1a\u63a2\u7d22\u6709\u671b\u63d0\u9ad8CAR-T\u7ec6\u80de\u7597\u6cd5\u836f\u7269\u9776\u70b9\u53ef\u53ca\u6027\u53ca\u7279\u5f02\u6027\u7684\u521b\u65b0\u6280\u672f\u3002\u5f00\u53d1\u4e86LADAR<sup>&reg;<\/sup>\u6280\u672f\uff0c\u5176\u4e2d\u76ee\u7684\u57fa\u56e0\u7684\u7ec6\u80de\u5185\u8f6c\u5f55\u7531\u5d4c\u5408\u8c03\u8282\u6297\u539f\u53d7\u4f53\u63a7\u5236\u3002\u901a\u8fc7LADAR<sup>&reg;<\/sup>\u4eba\u5de5\u53d7\u4f53\uff0c\u53ea\u6709\u5f53\u7ec6\u80de\u5916\u7ed3\u6784\u57df\u4e0e\u7279\u5b9a\u6297\u539f\u7ed3\u5408\u800c\u6fc0\u6d3b\u65f6\uff0c\u624d\u4f1a\u89e6\u53d1\u7ec6\u80de\u5185\u6d3b\u52a8\uff0c\u4ece\u800c\u6709\u53ef\u80fd\u7cbe\u786e\u63a7\u5236\u514d\u75ab\u7ec6\u80de\u5bf9\u764c\u7ec6\u80de\u53d1\u6325\u4f5c\u7528\u7684\u65f6\u95f4\u548c\u4f4d\u7f6e\u3002<\/li>\n<\/ul>\n<p>\u76ee\u524d\u516c\u53f8\u6b63\u5728\u5185\u90e8\u5f00\u53d1\u8fd9\u4e9b\u5177\u6709\u5168\u7403\u6743\u76ca\u7684\u6280\u672f\uff0c\u53ef\u72ec\u7acb\u6216\u8054\u5408\u7528\u4e8e\u5347\u7ea7\u73b0\u6709\u7684\u5019\u9009\u4ea7\u54c1\uff0c\u4ee5\u53ca\u5236\u9020\u672a\u6765\u7684\u521b\u65b0\u6027\u7ba1\u7ebf\u5019\u9009\u4ea7\u54c1\u3002<\/p>\n<p>\u622a\u81f32021\u5e7412\u670831\u65e5\uff0c\u79d1\u6d4e\u836f\u4e1a\u62e5\u6709300\u4f59\u9879\u4e13\u5229\uff0c\u5176\u4e2d\u670960\u4f59\u9879\u5168\u7403\uff08\u5305\u62ec\u4e2d\u56fd\u3001\u7f8e\u56fd\u3001\u6b27\u6d32\u53ca\u65e5\u672c\uff09\u6388\u6743\u4e13\u5229\u3002<\/p>\n<p><b>\u4e09\u3001\u4e2d\u7f8e\u4e24\u5730\u4ea7\u80fd\u6269\u5f20\uff0c\u72ec\u7acb\u81ea\u4e3b\u5236\u9020\u80fd\u529b\u52a0\u5f3a<\/b><\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\u5df2\u5728CAR-T\u5236\u9020\u7684\u5168\u90e8\u9636\u6bb5\u5efa\u7acb\u4e86\u7aef\u5bf9\u7aef\u7684\u7528\u4e8e\u4e34\u5e8a\u548c\u5546\u4e1a\u7684\u72ec\u7acb\u81ea\u4e3b\u7684\u5236\u9020\u80fd\u529b\uff0c\u5305\u62ec\u8d28\u7c92\u751f\u4ea7\u3001\u6162\u75c5\u6bd2\u8f7d\u4f53\u751f\u4ea7\u548cCAR-T\u7ec6\u80de\u751f\u4ea7\u3002\u5229\u7528\u516c\u53f8\u5728\u4e0a\u6d77\u5f90\u6c47\u533a\u7684\u751f\u4ea7\u5382\u623f\u4ee5\u53ca\u4f4d\u4e8e\u4e0a\u6d77\u91d1\u5c71\u533a\u7684\u5546\u4e1aGMP\u751f\u4ea7\u5de5\u5382\uff0c\u516c\u53f8\u4e00\u76f4\u80fd\u591f\u72ec\u7acb\u81ea\u4e3b\u5730\u751f\u4ea7CAR-T\u7ec6\u80de\u4ee5\u652f\u6301\u4e2d\u56fd\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u53ca\u72ec\u7acb\u81ea\u4e3b\u5730\u751f\u4ea7\u6162\u75c5\u6bd2\u8f7d\u4f53\u4ee5\u652f\u6301\u5168\u7403\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p>\u516c\u53f8\u6301\u7eed\u5728\u4e2d\u56fd\u53ca\u7f8e\u56fd\u6269\u5f20\u4ea7\u80fd\uff0c\u4ee5\u652f\u6301\u4e34\u5e8a\u8bd5\u9a8c\u548c\u968f\u540e\u7ba1\u7ebf\u4ea7\u54c1\u7684\u5546\u4e1a\u5316\uff0c\u516c\u53f8\u5728\u7f8e\u56fd\u5317\u5361\u7f57\u6765\u7eb3\u5dde\u8fbe\u52d2\u59c6\u5e02\u7684\u4e09\u89d2\u7814\u7a76\u56ed\uff08RTP\uff09\u533a\u57df\u5efa\u8bbe\u7684&nbsp;CGMP\u751f\u4ea7\u5de5\u5382\uff08&quot;RTP\u751f\u4ea7\u5de5\u5382&quot;\uff09\u5df2\u542f\u52a8\u8fd0\u8425\u3002RTP\u751f\u4ea7\u5de5\u5382\u603b\u5efa\u7b51\u9762\u79ef\u7ea6\u4e3a3300\u5e73\u65b9\u7c73\uff0c\u5c06\u6bcf\u5e74\u4e3a700\u540d\u60a3\u8005\u63d0\u4f9b\u989d\u5916\u7684\u81ea\u4f53CAR-T\u7ec6\u80de\u4ea7\u54c1\u4ea7\u80fd\uff0c\u4e5f\u5c06\u652f\u6301\u516c\u53f8\u6b63\u5728\u8fdb\u884c\u7684\u4e34\u5e8a\u7814\u7a76\u53ca\u4e8e\u5317\u7f8e\u548c\u6b27\u6d32\u7684\u65e9\u671f\u5546\u4e1a\u63a8\u5e7f\u3002<\/p>\n<p><b>\u56db\u3001\u7b7e\u8ba2\u5916\u90e8\u8bb8\u53ef\u534f\u8bae\uff0c\u52a9\u529b<\/b><b>CAR-T<\/b><b>\u4ea7\u54c1\u9020\u798f\u5168\u7403\u60a3\u8005<\/b><\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\u65d7\u4e0b\u516c\u53f8CAFA Therapeutics\u5df2\u4e0eHK inno.N Corporation\uff08KOSDAQ\uff1a195940\uff09\u8ba2\u7acb\u8bb8\u53ef\u534f\u8bae\uff0c\u4ee5\u5728\u97e9\u56fd\u5e02\u573a\u5f00\u53d1\u53ca\u5546\u4e1a\u5316CT032\u53caCT053\uff0c\u9996\u4ed8\u6b3e\u548c\u540e\u7eed\u91cc\u7a0b\u7891\u4ed8\u6b3e\u5171\u8ba1\u81f3\u591a\u4e94\u5343\u4e07\u7f8e\u5143\uff0c\u53e6\u5916\u516c\u53f8\u53ef\u4ee5\u83b7\u5f97\u57fa\u4e8e\u97e9\u56fd\u6240\u4ea7\u751f\u7684\u51c0\u9500\u552e\u989d\u81f3\u591a\u53cc\u4f4d\u6570\u767e\u5206\u6bd4\u7684\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u3002\u4e0e\u97e9\u56fd\u516c\u53f8\u7684\u5408\u4f5c\u5c55\u793a\u4e86\u79d1\u6d4e\u836f\u4e1a\u81f4\u529b\u4e8e\u4e0e\u9886\u5148\u7684\u5236\u836f\u4f01\u4e1a\u5efa\u7acb\u66f4\u591a\u7684\u5916\u90e8\u5408\u4f5c\uff0c\u4ee5\u6700\u5927\u9650\u5ea6\u5730\u5e94\u7528\u516c\u53f8\u7684\u6280\u672f\u5e73\u53f0\u548c\u7ba1\u7ebf\u4ea7\u54c1\u7684\u4ef7\u503c\uff0c\u4f7f\u5168\u7403\u66f4\u591a\u7684\u764c\u75c7\u60a3\u8005\u53d7\u76ca\u3002<\/p>\n<p><b>\u5173\u4e8e\u79d1\u6d4e\u836f\u4e1a<\/b><\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\uff08\u80a1\u7968\u4ee3\u7801\uff1a2171.HK\uff09\u662f\u4e00\u5bb6\u5728\u4e2d\u56fd\u53ca\u7f8e\u56fd\u62e5\u6709\u4e1a\u52a1\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u521b\u65b0CAR-T\u7ec6\u80de\u7597\u6cd5\u3002\u6211\u4eec\u5efa\u7acb\u4e86\u4e00\u4e2a\u7efc\u5408\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0\uff0c\u5176\u5185\u90e8\u80fd\u529b\u6db5\u76d6\u4ece\u9776\u70b9\u53d1\u73b0\u3001\u6297\u4f53\u5f00\u53d1\u3001\u4e34\u5e8a\u8bd5\u9a8c\u5230\u5546\u4e1a\u89c4\u6a21\u751f\u4ea7\u3002\u6211\u4eec\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\u65b0\u6280\u672f\u4ee5\u53ca\u62e5\u6709\u5168\u7403\u6743\u76ca\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u4ee5\u89e3\u51b3CAR-T\u7ec6\u80de\u7597\u6cd5\u7684\u91cd\u5927\u6311\u6218\uff0c\u6bd4\u5982\u63d0\u9ad8\u5b89\u5168\u6027\uff0c\u63d0\u9ad8\u6cbb\u7597\u5b9e\u4f53\u7624\u7684\u7597\u6548\u548c\u964d\u4f4e\u6cbb\u7597\u6210\u672c\u3002\u6211\u4eec\u7684\u4f7f\u547d\u662f\u6210\u4e3a\u80fd\u4e3a\u5168\u7403\u764c\u75c7\u60a3\u8005\u5e26\u6765\u521b\u65b0\u548c\u5dee\u5f02\u5316\u7684\u7ec6\u80de\u7597\u6cd5\uff0c\u5e76\u4f7f\u764c\u75c7\u53ef\u6cbb\u6108\u7684\u5168\u7403\u751f\u7269\u5236\u836f\u9886\u5bfc\u8005\u3002<\/p>\n<p><b>\u8054\u7cfb\u6211\u4eec<\/b><\/p>\n<p>\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a<a target=\"_blank\" href=\"https:\/\/www.carsgen.com\/\" rel=\"nofollow noopener\">https:\/\/www.carsgen.com\/<\/a> <br \/>\u5a92\u4f53\u8054\u7cfb\uff1a<a target=\"_blank\" href=\"mailto:PR@carsgen.com\" rel=\"nofollow noopener\">PR@carsgen.com<\/a><\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder0\">  <\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4e0a\u6d772022\u5e743\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u79d1\u6d4e\u836f\u4e1a\uff08\u80a1\u7968\u4ee3\u7801\uff1a2171.HK\uff09\uff0c\u4e00\u5bb6\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u521b\u65b0CAR-T\u7ec6\u80de\u7597\u6cd5\u516c\u53f8\uff0c\u53d1\u5e032021\u5e74\u5ea6\u4e1a\u7ee9\u62a5\u544a\u3002 \u4e1a\u7ee9\u4eae\u70b9\u901f\u89c8 CT053\u5b8c\u6210\u4e2d\u56fd\u5173\u952eII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5165\u7ec4\uff0c\u8ba1\u5212\u4e8e2022\u5e74\u4e0a\u534a\u5e74\u63d0\u4ea4NDA 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