{"id":65586,"date":"2022-03-23T11:00:00","date_gmt":"2022-03-23T04:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022032311000065586"},"modified":"2022-03-23T17:59:00","modified_gmt":"2022-03-23T09:59:00","slug":"%e7%a7%91%e6%b5%8e%e8%8d%af%e4%b8%9act041%e5%ae%8c%e6%88%90%e4%b8%ad%e5%9b%bd%e7%a1%ae%e8%af%81%e6%80%a7ii%e6%9c%9f%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e7%9a%84%e9%a6%96%e4%be%8b%e6%82%a3%e8%80%85","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022032311000065586","title":{"rendered":"\u79d1\u6d4e\u836f\u4e1aCT041\u5b8c\u6210\u4e2d\u56fd\u786e\u8bc1\u6027II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u9996\u4f8b\u60a3\u8005\u5165\u7ec4"},"content":{"rendered":"<p><p><span class=\"xn-subheadline\">\u4e3b\u8981\u6cbb\u7597\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c<\/span><\/p>\n<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" title=\"logo\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/Logo-312.jpg\" alt=\"\" width=\"118\" border=\"0\" hspace=\"0\" vspace=\"0\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4e0a\u6d772022\u5e743\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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id=\"spanHghlt881a\">\u5168\u7403\u9996\u4e2a\u4e14\u552f\u4e00<\/span>\u8fdb\u5165\u5230\u786e\u8bc1\u6027II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7528\u4e8e\u6cbb\u7597\u5b9e\u4f53\u7624\u7684CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\uff1b\u4e5f\u662f<span id=\"spanHghlte62d\">\u5168\u7403\u552f\u4e00<\/span>\u5df2\u83b7\u5f97\u7f8e\u56fdFDA\u548c\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u53ca\u52a0\u62ff\u5927\u536b\u751f\u90e8\u7684IND\/CTA\u6279\u51c6\u3001\u5e76\u6b63\u5728\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\u7814\u7a76\u7684\u9776\u5411CLDN18.2\u7684CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\u3002\u516c\u53f8\u8ba4\u4e3a\uff0cCT041\u6709\u53ef\u80fd\u5728\u672a\u6765\u6210\u4e3a\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u548c\u80f0\u817a\u764c\u7684\u9aa8\u5e72\u7597\u6cd5\u5e76\u60e0\u53ca\u5168\u7403\u5927\u91cf\u60a3\u8005\u3002<\/p>\n<p><strong>CT041<\/strong><strong>\u91cd\u8981\u76d1\u7ba1\u91cc\u7a0b\u7891\u4e8b\u4ef6\u4e00\u89c8<\/strong>\uff1a<\/p>\n<p>2020\u5e74\uff0c<br \/>CT041\u83b7\u7f8e\u56fdFDA\u6388\u4e88&ldquo;\u5b64\u513f\u836f&rdquo;\u8d44\u683c\uff0c\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\uff1b<\/p>\n<p>2021\u5e74\uff0c<br \/>CT041\u83b7\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u6388\u4e88&ldquo;\u5b64\u513f\u836f\u4ea7\u54c1&rdquo;\u8d44\u683c\uff0c\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u764c\uff1b<br \/>CT041\u83b7EMA\u6388\u4e88&ldquo;\u4f18\u5148\u836f\u7269&rdquo;\uff08PRIME\uff09\u8d44\u683c\uff0c\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u764c\u3002CT041\u4ea6\u662f<span id=\"spanHghlt75b6\">\u5168\u7403\u9996\u4e2a<\/span>\u5165\u9009PRIME\u8ba1\u5212\u7684\u5b9e\u4f53\u7624CAR-T\u4ea7\u54c1\uff1b<\/p>\n<p>2022\u5e74\uff0c<br 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id=\"DivAssetPlaceHolder1798\" class=\"PRN_ImbeddedAssetReference\">\n<p style=\"text-align: center;width: 100%\"><a href=\"https:\/\/mma.prnasia.com\/media2\/1771285\/image_1.html\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" title=\"\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/image_1-3028.jpg\" alt=\"\" \/><\/a><\/p>\n<\/p><\/div>\n<p><strong>\u5173\u4e8e<\/strong><strong>CT041<\/strong><\/p>\n<p>CT041\u662f\u4e00\u79cd\u6f5c\u5728<span id=\"spanHghlt5bc7\">\u5168\u7403\u540c\u7c7b\u9996\u521b<\/span>\u7684\u3001\u9776\u5411CLDN18.2\u7684\u81ea\u4f53CAR-T\u7ec6\u80de\u5019\u9009\u4ea7\u54c1\uff0c\u7528\u4e8e\u6cbb\u7597CLDN18.2\u9633\u6027\u5b9e\u4f53\u7624\uff0c\u4e3b\u8981\u6cbb\u7597\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u53ca\u80f0\u817a\u764c\u3002<\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\u5728\u4e2d\u56fd\u5f00\u5c55\u4e86\u7814\u7a76\u8005\u53d1\u8d77\u7684\u8bd5\u9a8c\u3001\u4e00\u9879\u9488\u5bf9\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u548c\u80f0\u817a\u764c\u7684Ib\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3001\u4e00\u9879\u9488\u5bf9\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c\u7684\u786e\u8bc1\u6027II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u53ca\u5728\u5317\u7f8e\u542f\u52a8\u4e86\u4e00\u9879\u9488\u5bf9\u665a\u671f\u80c3\u764c\u6216\u80f0\u817a\u764c\u76841b\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ea6\u62df\u4e8e2022\u5e74\u5728\u5317\u7f8e\u542f\u52a8\u5173\u952e2\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p><strong>\u5173\u4e8e<\/strong><strong>CLDN18.2<\/strong><\/p>\n<p>CLDN18.2\u662f\u4e00\u79cd\u9ad8\u5ea6\u9009\u62e9\u6027\u7684\u7ec6\u80de\u8c31\u7cfb\u6807\u8bb0\u7269\uff0c\u572870%\u81f380%\u80c3\u764c\u60a3\u8005\u53ca\u7ea660%\u80f0\u817a\u764c\u60a3\u8005\u7684\u764c\u7ec4\u7ec7\u4e2d\u666e\u904d\u8868\u8fbe\u3002CLDN18.2\u5728\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u7684\u8868\u8fbe\u4e25\u683c\u9650\u4e8e\u80c3\u9ecf\u819c\u5206\u5316\u7684\u4e0a\u76ae\u7ec6\u80de\uff0c\u5e76\u4e0d\u5b58\u5728\u4e8e\u80c3\u5e72\u7ec6\u80de\u533a\u3002CLDN18.2\u53ef\u5728\u6b63\u5e38\u7ec4\u7ec7\u7684\u6076\u6027\u8f6c\u5316\u4e2d\u4fdd\u7559\uff0c\u4ece\u800c\u4f7f\u5176\u5728\u6781\u5927\u6bd4\u4f8b\u7684\u539f\u53d1\u6027\u8f6c\u79fb\u6027\u80c3\u764c\u7ec6\u80de\u4e2d\u8868\u8fbe\u3002\u9664\u80c3\u764c\u7ec4\u7ec7\u5916\uff0cCLDN18.2\u5728\u5176\u4ed6\u7c7b\u578b\u5b9e\u4f53\u7624\uff08\u5982\u80f0\u817a\u764c\u53ca\u98df\u9053\u764c\uff09\u4e2d\u8868\u8fbe\u3002<\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\u5728\u5168\u7403\u8303\u56f4\u5185\u7387\u5148\u6210\u529f\u8bc6\u522b\u3001\u9a8c\u8bc1\u5e76\u62a5\u544aCLDN18.2\u53ef\u4f5c\u4e3a\u5176\u666e\u904d\u53ca\u9ad8\u8868\u8fbe\u7684\u5b9e\u4f53\u7624\u7684\u76f8\u5173\u6297\u539f\uff0c\u6709\u6f5c\u529b\u7528\u4e8e\u5f00\u53d1\u6cbb\u7597\u5b9e\u4f53\u7624\u7684CAR-T\u7597\u6cd5\u3002<\/p>\n<p><strong>\u5173\u4e8e\u79d1\u6d4e\u836f\u4e1a<\/strong><\/p>\n<p>\u79d1\u6d4e\u836f\u4e1a\uff08\u80a1\u7968\u4ee3\u7801\uff1a2171.HK\uff09\u662f\u4e00\u5bb6\u5728\u4e2d\u56fd\u53ca\u7f8e\u56fd\u62e5\u6709\u4e1a\u52a1\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e3b\u8981\u4e13\u6ce8\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u521b\u65b0CAR-T\u7ec6\u80de\u7597\u6cd5\u3002\u6211\u4eec\u5efa\u7acb\u4e86\u4e00\u4e2a\u7efc\u5408\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0\uff0c\u5176\u5185\u90e8\u80fd\u529b\u6db5\u76d6\u4ece\u9776\u70b9\u53d1\u73b0\u3001\u6297\u4f53\u5f00\u53d1\u3001\u4e34\u5e8a\u8bd5\u9a8c\u5230\u5546\u4e1a\u89c4\u6a21\u751f\u4ea7\u3002\u6211\u4eec\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\u65b0\u6280\u672f\u4ee5\u53ca\u62e5\u6709\u5168\u7403\u6743\u76ca\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u4ee5\u89e3\u51b3CAR-T\u7ec6\u80de\u7597\u6cd5\u7684\u91cd\u5927\u6311\u6218\uff0c\u6bd4\u5982\u63d0\u9ad8\u5b89\u5168\u6027\uff0c\u63d0\u9ad8\u6cbb\u7597\u5b9e\u4f53\u7624\u7684\u7597\u6548\u548c\u964d\u4f4e\u6cbb\u7597\u6210\u672c\u3002\u6211\u4eec\u7684\u4f7f\u547d\u662f\u6210\u4e3a\u80fd\u4e3a\u5168\u7403\u764c\u75c7\u60a3\u8005\u5e26\u6765\u521b\u65b0\u548c\u5dee\u5f02\u5316\u7684\u7ec6\u80de\u7597\u6cd5\uff0c\u5e76\u4f7f\u764c\u75c7\u53ef\u6cbb\u6108\u7684\u5168\u7403\u751f\u7269\u5236\u836f\u9886\u5bfc\u8005\u3002<\/p>\n<div id=\"DivAssetPlaceHolder6546\" class=\"PRN_ImbeddedAssetReference\">&nbsp;<\/div>\n<p><strong>\u8054\u7cfb\u6211\u4eec<\/strong><\/p>\n<p>\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a<a href=\"https:\/\/www.carsgen.com\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.carsgen.com\/<\/a><\/p>\n<div id=\"DivAssetPlaceHolder0\" class=\"PRN_ImbeddedAssetReference\">&nbsp;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4e3b\u8981\u6cbb\u7597\u665a\u671f\u80c3\u764c\/\u98df\u7ba1\u80c3\u7ed3\u5408\u90e8\u817a\u764c \u4e0a\u6d772022\u5e743\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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