{"id":64486,"date":"2022-03-09T20:00:00","date_gmt":"2022-03-09T13:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022030920000064486"},"modified":"2022-03-10T17:59:06","modified_gmt":"2022-03-10T09:59:06","slug":"%e5%a4%a9%e5%a2%83%e7%94%9f%e7%89%a9%e5%b0%86%e4%ba%8e2022%e7%be%8e%e5%9b%bd%e7%99%8c%e7%97%87%e7%a0%94%e7%a9%b6%e5%8d%8f%e4%bc%9a%ef%bc%88aacr%ef%bc%89%e5%b9%b4%e4%bc%9a%e5%85%ac%e5%b8%83%e5%a4%9a","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022030920000064486","title":{"rendered":"\u5929\u5883\u751f\u7269\u5c06\u4e8e2022\u7f8e\u56fd\u764c\u75c7\u7814\u7a76\u534f\u4f1a\uff08AACR\uff09\u5e74\u4f1a\u516c\u5e03\u591a\u6b3e\u5728\u7814\u65b0\u836f\u7684\u6700\u65b0\u7814\u7a76\u6210\u679c"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/APAC_Logo-102.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><p>\u4e2d\u56fd\u4e0a\u6d77\u548c\u7f8e\u56fd\u76d6\u745f\u65af\u58212022\u5e743\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>\u5929\u5883\u751f\u7269\u603b\u88c1\u6731\u79c0\u8f69\u535a\u58eb\u8868\u793a\uff1a\u201c\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u7684\u8f6c\u5316\u533b\u5b66\u7814\u7a76\u4e3a\u6211\u4eec\u7ee7\u7eed\u63a2\u7d22\u5176\u8054\u5408\u7597\u6cd5\u4ee5\u6cbb\u7597\u591a\u79cd\u5b9e\u4f53\u7624\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u6570\u636e\u652f\u6301\uff0c\u800cTJ-C64B\u7684\u4f5c\u7528\u673a\u7406\u7814\u7a76\u5219\u5bf9\u516c\u53f8\u8fdb\u4e00\u6b65\u63a8\u8fdb\u8fd9\u4e00\u521b\u65b0\u53cc\u6297\u7684\u4e34\u5e8a\u5f00\u53d1\u63d0\u4f9b\u4e86\u575a\u5b9e\u7684\u7406\u8bba\u4f9d\u636e\u3002\u5929\u5883\u751f\u7269\u5c06\u7ee7\u7eed\u52a0\u5feb\u4e34\u5e8a\u7814\u7a76\u548c\u7ba1\u7ebf\u5f00\u53d1\u811a\u6b65\uff0c\u529b\u4e89\u65e9\u65e5\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u591a\u521b\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002\u201d<\/p>\n<p>\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u662f\u9996\u6b3e\u9776\u5411B7-H3\u3001\u5177\u6709Fc\u4f18\u5316\u529f\u80fd\u7684\u5355\u514b\u9686\u6297\u4f53\u3002B7-H3\u5728\u8c03\u8282\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u4e2d\u8d77\u5173\u952e\u6027\u4f5c\u7528\uff0c\u5728\u591a\u79cd\u80bf\u7624\u4e2d\u5e7f\u6cdb\u8868\u8fbe\uff0c\u5176\u9ad8\u8868\u8fbe\u4e0e\u80bf\u7624\u9884\u540e\u4e0d\u4f73\u76f8\u5173\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u663e\u793a\uff0c\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u901a\u8fc7\u6297\u4f53\u4f9d\u8d56\u7ec6\u80de\u4ecb\u5bfc\u7684\u7ec6\u80de\u6bd2\u4f5c\u7528\u548c\u589e\u5f3aT\u7ec6\u80de\u514d\u75ab\u53cd\u5e94\u7684\u53cc\u91cd\u673a\u5236\uff0c\u8fbe\u5230\u6297\u80bf\u7624\u4f5c\u7528\u3002\u76ee\u524d\uff0c\u5929\u5883\u751f\u7269\u6b63\u5728\u4e2d\u56fd\u5f00\u5c55\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u4e0e<span id=\"spanHghlt6901\">\u5e15\u535a\u5229\u73e0<\/span>\u5355\u6297\uff08Keytruda<sup>&reg;<\/sup>\uff09\u8054\u5408\u6cbb\u7597\u5b9e\u4f53\u7624\uff08\u5305\u62ec\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u5c3f\u8def\u4e0a\u76ae\u764c\u4ee5\u53ca\u5176\u5b83\u7624\u79cd\uff09\u76842\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p>TJ-C64B\u662f\u5929\u5883\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u9776\u5411\u80bf\u7624\u6297\u539f\u5bc6\u86cb\u767dClaudin 6\u548cT\u7ec6\u80de\u5171\u523a\u6fc0\u5206\u5b504-1BB\u7684\u521b\u65b0\u53cc\u7279\u5f02\u6027\u6297\u4f53\uff0c\u4e5f\u662f\u516c\u53f8\u7b2c\u4e09\u6b3e\u57fa\u4e8e4-1BB\u5e73\u53f0\u6253\u9020\u7684\u53cc\u6297\u4ea7\u54c1\u3002Claudin 6\u662f\u4e00\u7c7b\u5728\u5375\u5de2\u764c\u3001\u777e\u4e38\u764c\u3001\u809d\u7ec6\u80de\u764c\u548c\u80ba\u817a\u764c\u7b49\u591a\u79cd\u764c\u75c7\u4e2d\u7279\u5f02\u8868\u8fbe\u7684\u80bf\u7624\u6297\u539f\u5bc6\u86cb\u767d\uff0c\u5728\u6210\u4eba\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u51e0\u4e4e\u68c0\u6d4b\u4e0d\u5230\u3002TJ-C64B\u72ec\u7279\u7684\u6297\u539f\u7ed3\u5408\u8868\u4f4d\uff0c\u4f7f\u5176\u5728\u4e0eClaudin 6\u7ed3\u5408\u65f6\u624d\u4f1a\u6fc0\u6d3b4-1BB\uff0c\u4ece\u800c\u6700\u5927\u7a0b\u5ea6\u907f\u514d\u4e86\u809d\u6bd2\u6027\u53ca\u5176\u4ed6\u7cfb\u7edf\u6bd2\u6027\u3002TJ-C64B\u6709\u671b\u6210\u4e3a\u6cbb\u7597\u5375\u5de2\u764c\u548c\u5176\u4ed6Claudin 6\u9633\u6027\u80bf\u7624\u7684\u65b0\u578b\u514d\u75ab\u7597\u6cd5\u3002<\/p>\n<p>\u4e24\u7bc7\u58c1\u62a5\u8be6\u7ec6\u5185\u5bb9\u5982\u4e0b\uff1a<\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"1\" class=\"prngen1\">\n<tbody>\n<tr>\n<td nowrap class=\"prngen3\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u6807\u9898<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>Inhibition of B7-H3 by Enoblituzumab Elicits Anti-Tumor Immune Modulation in Both Innate and Adaptive Immunity<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u6458\u8981\u7f16\u53f7:<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen5\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">4228<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u62a5\u544a\u8005:<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u5218\u5b66\u519b\u535a\u58eb<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u65e5\u671f\u53ca\u65f6\u95f4:<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">2022\u5e744\u670813\u65e5\uff08\u661f\u671f\u4e09&nbsp;\uff09<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f49:00&nbsp; \u2013 12:30<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>\u6458\u8981\uff1a<\/p>\n<ul type=\"disc\">\n<li>\u7814\u7a76\u901a\u8fc7\u4f7f\u7528Nanostring nCounter\u5e73\u53f0\u548c\u8d28\u8c31\u6d41\u5f0f\u7ec6\u80de\u6280\u672f(CyTOF)\uff0c\u5bf9B7-H3\u548c\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u5728\u4eba\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de(PBMCs)\u4e2d\u8c03\u8282\u514d\u75ab\u5e94\u7b54\u7684\u57fa\u56e0\u8868\u8fbe\u53ca\u514d\u75ab\u8868\u578b\u8fdb\u884c\u4e86\u7cfb\u7edf\u6027\u5206\u6790\u3002 <\/li>\n<li>\u7814\u7a76\u6570\u636e\u8bc1\u5b9e\u4e86B7-H3\u7684\u514d\u75ab\u6291\u5236\u529f\u80fd\uff0c\u5e76\u63d0\u793a\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u5177\u6709\u4e00\u7cfb\u5217\u514d\u75ab\u8c03\u8282\u529f\u80fd\uff0c\u5305\u62ec\u6d3b\u5316\u6bd2\u6740\u6027T\u7ec6\u80de\u548cNK\u7ec6\u80de\u3001\u9006\u8f6cT\u7ec6\u80de\u8017\u7aed\u3001\u6291\u5236M2\u578b\u9ad3\u7ec6\u80de\u7b49\u3002 <\/li>\n<li>\u7814\u7a76\u6570\u636e\u663e\u793a\uff0c\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u5728\u4f53\u5916\u5bf9\u8868\u8fbeB7-H3\u7684ES-2\uff08\u4eba\u5375\u5de2\u900f\u660e\u7ec6\u80de\u764c\u7ec6\u80de\uff09\u5c55\u73b0\u51fa\u4f18\u5f02\u7684\u80bf\u7624\u6740\u4f24\u6d3b\u6027\u3002\u4e0e\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u4e0a\u8c03T\u7ec6\u80de\u548cNK\u7ec6\u80de\u4e2d\u76844-1BB\u8868\u8fbe\u4e00\u81f4\uff0c\u901a\u8fc7urelumab\uff084-1BB\u6fc0\u52a8\u5242\uff09\u6fc0\u6d3b4-1BB\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u4ecb\u5bfc\u7684\u80bf\u7624\u6740\u4f24\u6d3b\u6027\u3002 <\/li>\n<li>\u8fd9\u4e9b\u8f6c\u5316\u533b\u5b66\u7814\u7a76\u53d1\u73b0\u4e3a\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u901a\u8fc7\u963b\u65adB7-H3\uff0c\u4e0e\u5176\u5b83\u514d\u75ab\u7597\u6cd5\u8054\u5408\u6cbb\u7597\u4ee5\u63d0\u9ad8\u5bf9\u591a\u79cd\u764c\u75c7\u7c7b\u578b\u7684\u7597\u6548\u63d0\u4f9b\u4e86\u7406\u8bba\u4f9d\u636e\u3002<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"1\" class=\"prngen1\">\n<tbody>\n<tr>\n<td nowrap class=\"prngen3\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u6807\u9898<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>Discovery of a Novel Claudin 6 x 4-1BB Bispecific Antibody with Potent Anti-Tumor Activity through Conditional 4-1BB Activation <\/b><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u6458\u8981\u7f16\u53f7:<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen5\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">5558<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u62a5\u544a\u8005:<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u674e\u952e\u535a\u58eb<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td nowrap class=\"prngen6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u65e5\u671f\u53ca\u65f6\u95f4:<\/span><\/p>\n<\/td>\n<td nowrap class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">2022\u5e744\u67088\u65e5\uff08\u661f\u671f\u4e94&nbsp;\uff09<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f413:00<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>\u6458\u8981\uff1a<\/p>\n<ul type=\"disc\">\n<li>\u4e34\u5e8a\u524d\u7814\u7a76\u6570\u636e\u8868\u660e\uff0cTJ-C64B\u5177\u6709\u72ec\u7279\u76844-1BB\u7ed3\u5408\u8868\u4f4d\uff0c\u5176\u4ec5\u5728\u4e0eClaudin 6\u7ed3\u5408\u7684\u60c5\u51b5\u4e0b\u624d\u4f1a\u523a\u6fc0&nbsp;4-1BB\u4fe1\u53f7\u5e76\u4ea7\u751f\u6297\u80bf\u7624\u6d3b\u6027\u3002\u8fd9\u4e00\u72ec\u7279\u7684\u6297\u539f\u4f9d\u8d56\u7279\u6027\u80fd\u591f\u6700\u5927\u9650\u5ea6\u907f\u514d\u809d\u6bd2\u6027\u53ca\u5176\u4ed6\u7cfb\u7edf\u6bd2\u6027\u3002 <\/li>\n<li>\u57284-1BB\u4eba\u6e90\u5316\u540c\u6e90\u80bf\u7624\u5c0f\u9f20\u6a21\u578b\u4e2d\uff0cTJ-C64B\u663e\u793a\u4e86\u5f3a\u5927\u7684\u80bf\u7624\u6291\u5236\u6d3b\u6027\uff0c\u540c\u65f6\u89c2\u5bdf\u5230\u80bf\u7624\u6d78\u6da6CD45+\u548cCD8+T\u7ec6\u80de\u6570\u91cf\u4ee5\u53caCD8\/Treg\u6bd4\u503c\u5347\u9ad8\uff0c\u63d0\u793aTJ-C64B\u80fd\u591f\u5728\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7279\u5f02\u6027\u6fc0\u6d3b\u514d\u75ab\u3002 <\/li>\n<li>TJ-C64B\u91cd\u590d\u7ed9\u836f\u540e\uff0c\u809d\u9176ALT \u53caAST\u6c34\u5e73\u65e0\u663e\u8457\u53d8\u5316\uff0c\u63d0\u793aTJ-C64B\u65e0\u660e\u663e\u7684\u809d\u6bd2\u6027\u98ce\u9669\u3002 <\/li>\n<li>\u4e34\u5e8a\u524d\u7814\u7a76\u6570\u636e\u8bc1\u5b9e\u4e86TJ-C64B\u72ec\u7279\u7684\u4f5c\u7528\u673a\u7406\uff0c\u5e76\u4e3a\u5176\u540e\u7eed\u4e34\u5e8a\u5f00\u53d1\u63d0\u4f9b\u4e86\u575a\u5b9e\u7684\u57fa\u7840\u3002<\/li>\n<\/ul>\n<p><b>\u5173\u4e8e\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297<\/b><\/p>\n<p>\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u662f\u9488\u5bf9B7\u5bb6\u65cf\u514d\u75ab\u8c03\u8282\u86cb\u767d\u4e2d\u7684B7-H3\u3001\u5177\u6709Fc\u4f18\u5316\u529f\u80fd\u7684\u5355\u514b\u9686\u6297\u4f53\u3002B7- H3\u5e7f\u6cdb\u8868\u8fbe\u4e8e\u591a\u79cd\u4e0d\u540c\u7c7b\u578b\u7684\u80bf\u7624\uff0c\u5728\u8c03\u8282\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u4e2d\u5177\u6709\u5173\u952e\u6027\u4f5c\u7528\u3002\u76f8\u5173\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u7ecf\u6216\u6b63\u5728\u5f00\u5c55\uff0c\u7528\u4e8e\u8bc4\u4f30\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u4f5c\u4e3a\u5355\u836f\u6cbb\u7597\u6216\u4e0eCTLA-4\u6216PD-1\u8054\u5408\u6cbb\u7597B7-H3\u8fc7\u5ea6\u8868\u8fbe\u7684\u80bf\u7624\u7684\u7597\u6548\u3002\u6839\u636e\u5929\u5883\u751f\u7269\u4e0eMacroGenics\u8fbe\u6210\u7684\u534f\u8bae\uff0c\u5929\u5883\u751f\u7269\u62e5\u6709\u4f9d\u5e03\u59a5\u7ec4\u5355\u6297\u5728\u4e2d\u56fd\u5927\u9646\u3001\u9999\u6e2f\u3001\u6fb3\u95e8\u53ca\u53f0\u6e7e\u5730\u533a\u7684\u72ec\u5bb6\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u6743\u5229\u3002<\/p>\n<p><b>\u5173\u4e8e<\/b><b>TJ-C64B<\/b><\/p>\n<p>TJ-C64B\u662f\u4e00\u6b3e\u540c\u65f6\u9776\u5411\u80bf\u7624\u6297\u539f\u5bc6\u86cb\u767dClaudin 6\uff08CLDN6\uff09\u548cT\u7ec6\u80de\u5171\u523a\u6fc0\u5206\u5b504-1BB\u7684\u521b\u65b0\u578b\u53cc\u7279\u5f02\u6027\u6297\u4f53\uff0c\u7528\u4e8e\u6cbb\u7597CLDN6\u9633\u6027\u80bf\u7624\u3002TJ-C64B\u53ef\u4ee5\u901a\u8fc7\u4e0eCLDN6\u7ed3\u5408\u6761\u4ef6\u6027\u6fc0\u6d3bT\u7ec6\u80de\uff0c\u4ece\u800c\u63d0\u4f9b\u66f4\u7cbe\u51c6\u3001\u9ad8\u6548\u7684\u514d\u75ab\u7cfb\u7edf\u6fc0\u6d3b\uff0c\u540c\u65f6\u51cf\u5c11\u7cfb\u7edf\u6027\u6bd2\u6027\u98ce\u9669\u3002\u76ee\u524d\uff0cTJ-C64B\u6b63\u5904\u4e8e\u4e34\u5e8a\u524d\u7814\u7a76\u9636\u6bb5\u3002<\/p>\n<p><b>\u5173\u4e8e\u5929\u5883\u751f\u7269<\/b><\/p>\n<p>\u5929\u5883\u751f\u7269\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aIMAB\uff09\u662f\u4e00\u5bb6\u521b\u65b0\u7684\u56fd\u9645\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u805a\u7126\u80bf\u7624\u514d\u75ab\u9886\u57df\u5dee\u5f02\u5316\u521b\u65b0\u751f\u7269\u836f\u7684\u7814\u53d1\u3001\u751f\u4ea7\u548c\u5546\u4e1a\u5316\u3002\u516c\u53f8\u4ee5\u201c\u6301\u7eed\u5f00\u53d1\u521b\u65b0\u751f\u7269\u836f\uff0c\u771f\u6b63\u6539\u53d8\u60a3\u8005\u751f\u6d3b\u201d\u4e3a\u4f7f\u547d\uff0c\u5728\u201c\u5feb\u901f\u4ea7\u54c1\u4e0a\u5e02\u201d\u548c\u201c\u5feb\u901f\u6982\u5ff5\u9a8c\u8bc1\u201d\u7684\u53cc\u8f6e\u7b56\u7565\u9a71\u52a8\u4e0b\uff0c\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\u548c\u5168\u7403\u6388\u6743\u5408\u4f5c\u7b49\u591a\u5143\u5316\u6a21\u5f0f\uff0c\u8fc5\u901f\u5efa\u7acb\u8d77\u62e5\u6709\u8d85\u8fc720\u4f59\u4e2a\u5177\u6709\u5168\u7403\u7ade\u4e89\u529b\u7684\u521b\u65b0\u836f\u7814\u53d1\u7ba1\u7ebf\u3002\u51ed\u501f\u9886\u5148\u7684\u65b0\u836f\u7814\u53d1\u5b9e\u529b\u4ee5\u53ca\u6b63\u5728\u5feb\u901f\u63a8\u8fdb\u7684GMP\u751f\u4ea7\u80fd\u529b\u548c\u5546\u4e1a\u5316\u5e03\u5c40\uff0c\u516c\u53f8\u6b63\u8fc5\u901f\u4ece\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u79d1\u6280\u516c\u53f8\u6210\u957f\u4e3a\u8986\u76d6\u5168\u4ea7\u4e1a\u94fe\u7684\u7efc\u5408\u6027\u5168\u7403\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u5728\u4e0a\u6d77\uff08\u603b\u90e8\uff09\u3001\u5317\u4eac\u3001\u676d\u5dde\u3001\u5e7f\u5dde\u3001\u4e3d\u6c34\u3001\u9999\u6e2f\u5747\u8bbe\u6709\u529e\u516c\u5ba4\uff0c\u5e76\u5728\u7f8e\u56fd\u9a6c\u91cc\u5170\u5dde\u548c\u52a0\u5dde\u5723\u8fed\u6208\u8bbe\u6709\u7814\u53d1\u4e2d\u5fc3\u5e76\u5f62\u6210\u7f8e\u56fd\u7814\u53d1\u603b\u90e8\u3002\u66f4\u591a\u4fe1\u606f\u8bf7\u8bbf\u95ee<u><a target=\"_blank\" href=\"http:\/\/ir.i-mabbiopharma.com\/\" rel=\"nofollow noopener\">http:\/\/ir.i-mabbiopharma.com<\/a><\/u>\u5e76\u5173\u6ce8\u5929\u5883\u751f\u7269<u><a target=\"_blank\" href=\"https:\/\/www.linkedin.com\/company\/i-mab\/\" rel=\"nofollow noopener\">\u9886\u82f1<\/a><\/u>\u3001<u><a target=\"_blank\" href=\"https:\/\/twitter.com\/IMabBiopharma\" rel=\"nofollow noopener\">\u63a8\u7279<\/a><\/u>\u53ca<u><a target=\"_blank\" href=\"https:\/\/mp.weixin.qq.com\/s\/_s634aizyQPuq1Vgf-hLGA\" rel=\"nofollow noopener\">\u5fae\u4fe1<\/a><\/u>\u5b98\u65b9\u8d26\u53f7\u3002<\/p>\n<p><b>\u5929\u5883\u751f\u7269\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u5305\u542b\u6839\u636e\u300a1995 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cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u9f99\u6c5f\uff0c\u9996\u5e2d\u8d22\u52a1\u5b98<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:IR@i-mabbiopharma.com\" class=\"prnews_a\" rel=\"nofollow noopener\">IR@i-mabbiopharma.com<\/a><\/span><\/p>\n<\/td>\n<td class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u51af\u7426\uff0c\u9996\u5e2d\u4f20\u64ad\u5b98<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:PR@i-mabbiopharma.com\" class=\"prnews_a\" rel=\"nofollow noopener\">PR@i-mabbiopharma.com<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p><b>\u6295\u8d44\u8005\u54a8\u8be2<\/b><\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prngen4\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">The Piacente Group, Inc.<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">Emilie Wu<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">E-mail:&nbsp;<a target=\"_blank\" href=\"mailto:emilie@thepiacentegroup.com\" class=\"prnews_a\" rel=\"nofollow noopener\"><u>emilie@thepiacentegroup.com<\/u><\/a><\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">Office line: +86 21 6039 8363<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>&nbsp;<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder2\">  <\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u56fd\u4e0a\u6d77\u548c\u7f8e\u56fd\u76d6\u745f\u65af\u58212022\u5e743\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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6\u7ed3\u5408\u65f6\u624d\u4f1a\u6fc0\u6d3b4-1BB\uff0c\u4ece\u800c\u6700\u5927\u7a0b\u5ea6\u907f\u514d\u4e86\u809d\u6bd2\u6027\u53ca\u5176\u4ed6\u7cfb\u7edf\u6bd2\u6027\u3002TJ-C64B\u6709\u671b\u6210\u4e3a\u6cbb\u7597\u5375\u5de2\u764c\u548c\u5176\u4ed6Claudin 6\u9633\u6027\u80bf\u7624\u7684\u65b0\u578b\u514d\u75ab\u7597\u6cd5\u3002 \u4e24\u7bc7\u58c1\u62a5\u8be6\u7ec6\u5185\u5bb9\u5982\u4e0b\uff1a \u6807\u9898 Inhibition of B7-H3 by Enoblituzumab Elicits Anti-Tumor Immune Modulation in Both Innate and Adaptive Immunity \u6458\u8981\u7f16\u53f7: 4228 \u62a5\u544a\u8005: \u5218\u5b66\u519b\u535a\u58eb \u65e5\u671f\u53ca\u65f6\u95f4: 2022\u5e744\u670813\u65e5\uff08\u661f\u671f\u4e09&nbsp;\uff09 \u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f49:00&nbsp; \u2013 12:30 \u6458\u8981\uff1a \u7814\u7a76\u901a\u8fc7\u4f7f\u7528Nanostring 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4-1BB Bispecific Antibody&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2022030920000064486\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":64489,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-64486","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/64486","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=64486"}],"version-history":[{"count":2,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/64486\/revisions"}],"predecessor-version":[{"id":64490,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/64486\/revisions\/64490"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/64489"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=64486"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=64486"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=64486"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}