\u4e0a\u6d772022\u5e743\u67082\u65e5 \/\u7f8e\u901a\u793e\/ — \u518d\u9f0e\u533b\u836f\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aZLAB\uff1b\u9999\u6e2f\u8054\u4ea4\u6240\u80a1\u7968\u4ee3\u7801\uff1a9688\uff09\uff0c\u4e00\u5bb6\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\u7684\u3001\u5904\u4e8e\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u521b\u65b0\u578b\u5168\u7403\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4eca\u5929\u516c\u5e03\u4e86\u622a\u81f32021\u5e7412\u670831\u65e5\u6b6212\u4e2a\u6708\u7684\u8d22\u52a1\u4e1a\u7ee9\uff0c\u4ee5\u53ca\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\u548c\u516c\u53f8\u8fdb\u5c55\u3002 <\/p>\n
\u518d\u9f0e\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u675c\u83b9\u535a\u58eb\u8868\u793a\uff1a\u201c 2021\u5e74\uff0c\u518d\u9f0e\u533b\u836f\u7ee7\u7eed\u5728\u6211\u4eec\u4e1a\u52a1\u7684\u6240\u6709\u9886\u57df\u53d6\u5f97\u5f3a\u52b2\u7684\u589e\u957f\u548c\u4e1a\u7ee9\u8868\u73b0\u3002\u6211\u4eec\u663e\u8457\u592f\u5b9e\u4e86\u7531\u8bf8\u591a\u6f5c\u5728\u540c\u7c7b\u9996\u521b\u548c\/\u6216\u6f5c\u5728\u540c\u7c7b\u6700\u4f18\u4ea7\u54c1\u7ec4\u6210\u7684\u4ea7\u54c1\u7ba1\u7ebf\u3002\u6211\u4eec11\u6b3e\u62e5\u6709\u5168\u7403\u6743\u5229\u7684\u5185\u90e8\u7814\u53d1\u836f\u7269\uff0c\u53d6\u5f97\u91cd\u8981\u7684\u7814\u53d1\u8fdb\u5c55\uff0c\u5176\u4e2d\u7528\u4e8e\u6cbb\u7597\u6162\u6027\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u7684\u6297IL-17A Humabody®ZL-1102\u5df2\u7ecf\u8fbe\u6210\u6982\u5ff5\u9a8c\u8bc1\u3002\u901a\u8fc7\u5546\u52a1\u62d3\u5c55\uff0c\u6211\u4eec\u83b7\u5f97\u56db\u6b3e\u9887\u5177\u524d\u666f\u7684\u80bf\u7624\u5019\u9009\u836f\u7269\u7684\u8bb8\u53ef\uff0c\u8fdb\u4e00\u6b65\u62d3\u6df1\u516c\u53f8\u4e16\u754c\u4e00\u6d41\u7684\u80c3\u764c\u548c\u80ba\u764c\u7ba1\u7ebf\uff1b\u6211\u4eec\u83b7\u5f97\u5177\u6709\u5355\u4ea7\u54c1\u591a\u9002\u5e94\u8bc1\u6f5c\u529b\u7684efgartigimod\u7684\u8bb8\u53ef\uff0c\u589e\u5f3a\u4e86\u81ea\u8eab\u514d\u75ab\u7ba1\u7ebf\uff1b\u6211\u4eec\u8fd8\u8fbe\u6210\u5173\u4e8eKarXT\u7684\u5408\u4f5c\uff0c\u5c06\u75be\u75c5\u9886\u57df\u62d3\u5c55\u81f3\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u3002\u6b64\u5916\uff0c\u6211\u4eec\u5728\u6ce8\u518c\u4e8b\u52a1\u65b9\u9762\u4e5f\u53d6\u5f97\u4e00\u5b9a\u6210\u7ee9\uff0c\u5305\u62ec\u9996\u6b3e\u975e\u80bf\u7624\u4ea7\u54c1\u7ebd\u518d\u4e50®\u83b7\u6279\u3002\u6211\u4eec\u7684\u56db\u6b3e\u5df2\u4e0a\u5e02\u4ea7\u54c1\uff0c\u4e3a\u516c\u53f8\u7684\u5546\u4e1a\u5316\u5de5\u4f5c\u4e0d\u65ad\u589e\u52bf\u6dfb\u80fd\u3002\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u5219\u4e50®\u5375\u5de2\u764c\u4e00\u7ebf\u7ef4\u6301\u6cbb\u7597\u9002\u5e94\u8bc1\u6210\u529f\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\uff0c\u6211\u4eec\u671f\u5f85\u5219\u4e50\u80fd\u591f\u51ed\u501f\u5176\u9488\u5bf9\u5375\u5de2\u764c\u60a3\u8005\uff08\u65e0\u8bba\u5176\u751f\u7269\u6807\u8bb0\u7269\u72b6\u6001\u5982\u4f55\uff09\u7684\u72ec\u7279\u4f18\u52bf\uff0c\u6210\u4e3a\u4e2d\u56fd\u5375\u5de2\u764c\u9886\u57df\u9886\u5148\u7684PARP\u6291\u5236\u5242\u3002\u6700\u540e\uff0c\u6211\u4eec\u4eba\u624d\u6d4e\u6d4e\u3001\u6a2a\u8de8\u4e2d\u7f8e\u4e24\u5730\u7684\u5168\u7403\u56e2\u961f\u8fdb\u4e00\u6b65\u58ee\u5927\uff0c\u4e3a\u672a\u6765\u7684\u6301\u7eed\u589e\u957f\u6253\u4e0b\u575a\u5b9e\u7684\u57fa\u7840\u3002\u201d<\/p>\n
\u8fd1\u671f\u5176\u5b83\u4e1a\u7ee9<\/b><\/p>\n
\u4e34\u5e8a\u5f00\u53d1<\/b><\/p>\n
\u25cf \u516c\u5e03\u4e86\u8212\u5df4\u5766-durlobactam (SUL-DUR) \u6cbb\u7597\u4e0d\u52a8\u6746\u83cc\u611f\u67d3\u7684\u5168\u74033\u671fATTACK\u7814\u7a76\u7684\u9633\u6027\u4e3b\u8981\u7ed3\u679c\u3002<\/p>\n
\u25cf \u518d\u9f0e\u533b\u836f\u5df2\u5728\u4e2d\u56fd\u5185\u5730\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u4e2d\u56fd\u201d\uff09\u542f\u52a8efgartigimod\u6cbb\u7597\u539f\u53d1\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08ITP\uff09\u3001\u6162\u6027\u708e\u6027\u8131\u9ad3\u9798\u6027\u591a\u53d1\u6027\u795e\u7ecf\u6839\u795e\u7ecf\u75c5\uff08CIDP\uff09\u3001\u5929\u75b1\u75ae\u53ca\u836f\u4ee3\u52a8\u529b\u5b66\u7684\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n
\u6ce8\u518c\u4e8b\u52a1<\/b><\/p>\n
\u25cf \u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34argenx BV (argenx) \u5df2\u5728\u7f8e\u56fd\u83b7\u5f97efgartigimod\u7528\u4e8e\u6cbb\u7597gMG\u7684\u6279\u51c6\u3002<\/p>\n
\u25cf \u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34Mirati Therapeutics, Inc. (Mirati) \u5df2\u5728\u7f8e\u56fd\u63d0\u4ea4adagrasib\u7528\u4e8e\u6cbb\u7597\u4e8c\u7ebf\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7 (NDA)\u3002<\/p>\n
\u25cf NMPA\u53d7\u7406\u518d\u9f0e\u533b\u836f\u63d0\u4ea4\u7684\u9a6c\u5409\u59a5\u6614\u5355\u6297\u5728\u56fd\u5185\u7528\u4e8e\u6cbb\u7597HER2\u9633\u6027\u4e73\u817a\u764c\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n
\u5546\u52a1\u62d3\u5c55<\/b><\/p>\n
\u25cf \u518d\u9f0e\u533b\u836f\u4e0eKaruna Therapeutics, Inc.\u5c31KarXT\uff08xanomeline-trospium\uff09\u5728\u5927\u4e2d\u534e\u533a\u7684\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u5546\u4e1a\u5316\u8fbe\u6210\u72ec\u5bb6\u8bb8\u53ef\u534f\u8bae\u3002<\/p>\n
\u25cf \u518d\u9f0e\u533b\u836f\u4e0eBlueprint Medicines Corporation (Blueprint) \u5c31\u5728\u5927\u4e2d\u534e\u533a\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7528\u4e8e\u6cbb\u7597\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u9a71\u52a8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u7684BLU-945\u548cBLU-701\u8fbe\u6210\u72ec\u5bb6\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\u3002<\/p>\n
\u5546\u4e1a\u5316<\/b><\/p>\n
\u25cf \u7ebd\u518d\u4e50®\uff08\u7532\u82ef\u78fa\u9178\u5965\u9a6c\u73af\u7d20\uff09\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u83b7NMPA\u6279\u51c6\uff0c\u5e76\u4e8e2021\u5e7412\u6708\u5728\u4e2d\u56fd\u4e0a\u5e02\u3002<\/p>\n
\u675c\u83b9\u535a\u58eb\u603b\u7ed3\u9053\uff1a\u201c 2022\u5e74\u5bf9\u4e8e\u518d\u9f0e\u6765\u8bf4\uff0c\u662f\u5173\u952e\u7684\u4e00\u5e74\uff0c\u6211\u4eec\u5e0c\u671b\u5728\u5f15\u9886\u884c\u4e1a\u521b\u65b0\u7684\u540c\u65f6\uff0c\u7ee7\u7eed\u5728\u5173\u952e\u9886\u57df\u5de9\u56fa\u548c\u53d1\u5c55\u6211\u4eec\u7684\u6218\u7565\u6027\u4f18\u52bf\u3002\u6211\u4eec\u8ba1\u5212\u901a\u8fc7\u52a0\u5feb\u6240\u6709\u4ea7\u54c1\u7ba1\u7ebf\u7684\u91cd\u8981\u6570\u636e\u89e3\u8bfb\u548c\u6ce8\u518c\u7533\u8bf7\uff0c\u4f7f\u836f\u7269\u66f4\u5feb\u60e0\u53ca\u60a3\u8005\u3002\u6211\u4eec\u5e0c\u671b\u52a0\u5feb\u5728\u4e2d\u56fd\u63d0\u4ea4efgartigimod\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u7684\u8fdb\u7a0b\uff0c\u5e76\u5728\u4e2d\u56fd\u542f\u52a8bemarituzumab\u6cbb\u7597\u4e00\u7ebf\u665a\u671f\u80c3\u764c\u548c\u80c3\u98df\u7ba1\u4ea4\u754c\u90e8\uff08GEJ\uff09\u764c\u7684\u6ce8\u518c\u6027\u7814\u7a76\u3002\u6211\u4eec\u5c06\u7ee7\u7eed\u6295\u8d44\u7814\u53d1\u5e76\u63a8\u8fdb\u6211\u4eec\u62e5\u6709\u5168\u7403\u6743\u5229\u7684\u5185\u90e8\u7ba1\u7ebf\u3002\u6211\u4eec\u8ba1\u5212\u5168\u9762\u63a8\u8fdb\u6211\u4eec\u7684\u6297IL-17A Humabody® ZL-1102\u8fdb\u5165\u5168\u7403\u5f00\u53d1\uff0c\u5e76\u4e8e 2022\u5e74\u63d0\u4ea4\u6700\u591a\u81f3\u4e24\u4e2a\u62e5\u6709\u5168\u7403\u6743\u5229\u7684\u5316\u5408\u7269\u7684\u65b0\u836f\u4e34\u5e8a\u7814\u7a76\uff08IND\uff09\u7533\u8bf7\u3002\u6211\u4eec\u5c06\u5229\u7528\u81ea\u8eab\u5728\u4e2d\u56fd\u7684\u9886\u5148\u4f18\u52bf\u52a0\u901f\u6536\u5165\u589e\u957f\uff0c\u5e76\u51ed\u501f\u6f5c\u5728\u53d8\u9769\u6027\u7684\u4ea7\u54c1\u7ba1\u7ebf\u548c\u5408\u4f5c\u673a\u4f1a\uff0c\u5bfb\u6c42\u5185\u5916\u90e8\u521b\u65b0\u3002\u6211\u4eec\u7684\u4f7f\u547d\u662f\u6253\u9020\u5168\u7403\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002<\/p>\n
\u5c55\u671b\u672a\u6765\uff0c\u6211\u4eec\u7684\u76ee\u6807\u662f\u52302025\u5e74\u62e5\u6709\u81f3\u5c1115\u6b3e\u4e0a\u5e02\u4ea7\u54c1\uff0c\u8986\u76d6\u8d85\u8fc730\u4e2a\u9002\u5e94\u8bc1\u3002\u6211\u4eec\u76f8\u4fe1\uff0c\u653f\u7b56\u73af\u5883\u5c06\u7ee7\u7eed\u5229\u597d\u518d\u9f0e\u533b\u836f\u8fd9\u6837\u7684\u521b\u65b0\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u6211\u4eec\u4e5f\u5bf9\u518d\u9f0e\u9ad8\u5ea6\u5dee\u5f02\u5316\u4e14\u4e16\u754c\u4e00\u6d41\u4ea7\u54c1\u7ba1\u7ebf\u7684\u957f\u671f\u5e02\u573a\u6f5c\u529b\u5145\u6ee1\u4fe1\u5fc3\uff0c\u8fd9\u4e9b\u4ea7\u54c1\u65e8\u5728\u89e3\u51b3\u672a\u6ee1\u8db3\u7684\u5de8\u5927\u60a3\u8005\u9700\u6c42\uff0c\u5e76\u4e3a\u884c\u4e1a\u521b\u9020\u4ef7\u503c\u3002\u6211\u4eec\u5c06\u4e00\u5982\u65e2\u5f80\u5730\u6301\u7eed\u6295\u8d44\u5185\u90e8\u7814\u53d1\uff0c\u4ee5\u5353\u8d8a\u7684\u6267\u884c\u529b\u4e0d\u65ad\u521b\u9020\u66f4\u591a\u4f73\u7ee9\uff0c\u4ee5\u5b9e\u73b0\u6211\u4eec\u60e0\u53ca\u5168\u7403\u60a3\u8005\u7684\u4f7f\u547d\u3002\u201d<\/p>\n
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\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2021\u5e7412\u6708\uff0c\u5219\u4e50\u88ab\u7eb3\u5165\u4e2d\u56fd\u56fd\u5bb6\u533b\u7597\u4fdd\u969c\u5c40\uff08NHSA\uff09\u6700\u65b0\u53d1\u5e03\u7684\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\uff0c\u7528\u4e8e\u665a\u671f\u4e0a\u76ae\u6027\u5375\u5de2\u764c\u3001\u8f93\u5375\u7ba1\u764c\u6216\u539f\u53d1\u6027\u8179\u819c\u764c\uff08\u7edf\u79f0\u4e3a\u5375\u5de2\u764c\uff09\u6210\u4eba\u60a3\u8005\u5bf9\u542b\u94c2\u5316\u7597\u4ea7\u751f\u5e94\u7b54\u540e\u7684\u4e00\u7ebf\u7ef4\u6301\u6cbb\u7597\uff0c\u65e0\u8bba\u751f\u7269\u6807\u8bb0\u7269\u72b6\u6001\u5982\u4f55\u3002 <\/p>\n
2021\u5e7411\u6708\uff0c\u5219\u4e50\u4f5c\u4e3a\u7ef4\u6301\u6cbb\u7597\u836f\u7269\u76843\u671fPRIME\u7814\u7a76\u8fbe\u5230\u5176\u4e3b\u8981\u7ec8\u70b9\u3002\u5bf9\u4e8e\u65b0\u8bca\u65ad\u7684\u665a\u671f\u5375\u5de2\u764c\u4e2d\u56fd\u60a3\u8005\uff08\u65e0\u8bba\u751f\u7269\u6807\u8bb0\u7269\u72b6\u6001\u5982\u4f55\uff09\uff0c\u5728\u63a5\u53d7\u542b\u94c2\u5316\u7597\u4ea7\u751f\u5e94\u7b54\u540e\uff0c\u5219\u4e50\u53ef\u4f7f\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u5728\u7edf\u8ba1\u5b66\u548c\u4e34\u5e8a\u610f\u4e49\u4e0a\u5747\u5f97\u5230\u663e\u8457\u7684\u83b7\u76ca\uff0c\u4e14\u5b89\u5168\u6027\u53ef\u8010\u53d7\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u57282022\u5e74\u7f8e\u56fd\u5987\u79d1\u80bf\u7624\u5b66\u4f1a\uff08SGO\uff09\u5e74\u4f1a\u4e0a\u516c\u5e033\u671fPRIME\u7814\u7a76\u7684\u4e34\u5e8a\u6570\u636e\u3002<\/p>\n
\u7ee7\u7eed\u63a2\u7d22\u4e0e\u5176\u5b83\u836f\u7269\u8054\u7528\u7684\u673a\u4f1a\u3002<\/p>\n
\u80bf\u7624\u7535\u573a\u6cbb\u7597<\/b><\/p>\n
\u80bf\u7624\u7535\u573a\u6cbb\u7597\u662f\u4e00\u79cd\u5229\u7528\u7279\u5b9a\u9891\u7387\u7684\u7535\u573a\u5e72\u6270\u80bf\u7624\u7ec6\u80de\u5206\u88c2\u7684\u764c\u75c7\u7597\u6cd5\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2022\u5e741\u6708\uff0c\u5728\u7528\u4e8e\u8bc4\u4f30\u80bf\u7624\u7535\u573a\u6cbb\u7597\u8054\u5408\u767d\u86cb\u767d\u7ed3\u5408\u578b\u7d2b\u6749\u9187\u548c\u5409\u897f\u4ed6\u6ee8\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u80f0\u817a\u764c\u60a3\u8005\u76843\u671f\u5173\u952e\u7814\u7a76PANOVA-3\u4e2d\uff0c\u5927\u4e2d\u534e\u533a\u9996\u4f8b\u60a3\u8005\u63a5\u53d7\u4e86\u6cbb\u7597\u3002<\/p>\n
\u81ea2020\u5e74\u7b2c\u4e09\u5b63\u5ea6\u5728\u4e2d\u56fd\u5546\u4e1a\u4e0a\u5e02\u4ee5\u6765\uff0c\u622a\u81f32022\u5e741\u670831\u65e5\uff0c\u7231\u666e\u76fe\u5df2\u88ab\u5217\u5165\u7531\u7701\u7ea7\u6216\u5e02\u7ea7\u653f\u5e9c\u6307\u5bfc\u768433\u4e2a\u57ce\u5e02\u666e\u60e0\u9669\u3002<\/p>\n
2021\u5e7412\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5411NMPA\u63d0\u4ea4\u4e86\u7528\u4e8e\u6cbb\u7597\u6076\u6027\u80f8\u819c\u95f4\u76ae\u7624\u7684\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\uff08MAA\uff09\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u9884\u8ba1\u5c06\u4e8e2022\u5e74\u5e74\u5e95\u516c\u5e033\u671f\u5173\u952e\u7814\u7a76LUNAR\u7684\u4e3b\u8981\u6570\u636e\uff0c\u8be5\u7814\u7a76\u8bc4\u4f30\u80bf\u7624\u7535\u573a\u6cbb\u7597\u8054\u5408\u533b\u5e08\u9009\u62e9\u7684\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6216\u591a\u897f\u4ed6\u8d5b\u6cbb\u75974\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684\u7597\u6548\u3002<\/p>\n
Novocure\u9884\u8ba1\u72ec\u7acb\u6570\u636e\u76d1\u6d4b\u59d4\u5458\u4f1a\uff08DMC\uff09\u5c06\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u5bf9Novocure 3\u671f\u5173\u952e\u7814\u7a76INNOVATE-3\u8fdb\u884c\u4e2d\u671f\u5206\u6790\uff0c\u8be5\u7814\u7a76\u8bc4\u4f30\u80bf\u7624\u7535\u573a\u6cbb\u7597\u8054\u5408\u7d2b\u6749\u9187\u6cbb\u7597\u94c2\u8010\u836f\u5375\u5de2\u764c\u60a3\u8005\u7684\u7597\u6548\u3002<\/p>\n
\u518d\u9f0e\u533b\u836f\u4e0eNovocure\u5408\u4f5c\uff0c\u9884\u8ba1\u5c06\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u516c\u5e03\u80c3\u764c2\u671f\u5148\u5bfc\u7814\u7a76EF-31\u7684\u6570\u636e\uff0c\u8be5\u7814\u7a76\u8bc4\u4f30\u80bf\u7624\u7535\u573a\u6cbb\u7597\u8054\u5408\u5316\u7597\u6cbb\u7597\u80c3\u764c\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002<\/p>\n
\u64ce\u4e50<\/b>®<\/b>\uff08\u745e\u6d3e\u66ff\u5c3c\uff09<\/b><\/p>\n
\u64ce\u4e50\u662f\u4e00\u6b3e\u5f00\u5173\u63a7\u5236\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff0c\u7ecf\u8bbe\u8ba1\u4ee5\u5e7f\u6cdb\u6291\u5236\u7a81\u53d8\u7684KIT\u53caPDGFR\u03b1\u6fc0\u9176\uff0c\u662f\u552f\u4e00\u5728\u7f8e\u56fd\u548c\u4e2d\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u6240\u6709\u66fe\u63a5\u53d7\u8fc7\u4e09\u79cd\u6216\u4ee5\u4e0a\u6fc0\u9176\u6291\u5236\u5242\u6cbb\u7597\u7684\u665a\u671f\u80c3\u80a0\u95f4\u8d28\u7624 (GIST) \u60a3\u8005\u7684\u7597\u6cd5\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2021\u5e7411\u6708\uff0c\u6b27\u76df\u59d4\u5458\u4f1a\u6279\u51c6\u64ce\u4e50\u7528\u4e8e\u6cbb\u7597\u56db\u7ebfGIST\u3002<\/p>\n
\u81ea2021\u5e745\u6708\u5728\u4e2d\u56fd\u5546\u4e1a\u4e0a\u5e02\u4ee5\u6765\uff0c\u622a\u81f32022\u5e741\u670831\u65e5\uff0c\u64ce\u4e50\u5df2\u88ab\u5217\u516552\u4e2a\u57ce\u5e02\u666e\u60e0\u9669\u3002<\/p>\n
Adagrasib<\/b><\/p>\n
Adagrasib\u662f\u4e00\u6b3e\u9ad8\u9009\u62e9\u6027\u7684\u5f3a\u6548\u53e3\u670d\u5c0f\u5206\u5b50KRASG12C\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597KRASG12C\u7a81\u53d8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u7ed3\u76f4\u80a0\u764c (CRC) \u3001\u80f0\u817a\u764c\u548c\u5176\u5b83\u5b9e\u4f53\u7624\u3002 <\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
FDA\u53d7\u7406adagrasib\u7528\u4e8e\u6cbb\u7597\u66fe\u7ecf\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u6b21\u7cfb\u7edf\u6027\u6cbb\u7597\u7684KRASG12C\u7a81\u53d8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff0c\u5904\u65b9\u836f\u4f7f\u7528\u8005\u4ed8\u8d39\u6cd5\u6848\uff08PDUFA\uff09\u7684\u65e5\u671f\u4e3a2022\u5e7412\u670814\u65e5\u3002<\/p>\n
2022\u5e741\u6708\uff0cKRYSTAL-1\u7814\u7a76\u76842\u671f\u961f\u5217\u53d6\u5f97\u9633\u6027\u7ed3\u679c\uff0c\u8be5\u7814\u7a76\u65e8\u5728\u8bc4\u4f30adagrasib\u6cbb\u7597KRASG12C\u7a81\u53d8\u6d88\u5316\u9053\uff08GI\uff09\u80bf\u7624\u60a3\u8005\u7684\u6548\u679c\u3002\u7ed3\u679c\u663e\u793aadagrasib\u8868\u73b0\u51fa\u663e\u8457\u7684\u4e34\u5e8a\u6d3b\u6027\u548c\u5e7f\u6cdb\u7684\u75be\u75c5\u63a7\u5236\u6548\u679c\u3002 <\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u5b8c\u6210\u9488\u5bf9\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u548cCRC\u7684\u5168\u7403\u6f5c\u5728\u6ce8\u518c\u6027\u7814\u7a76\u7684\u5927\u4e2d\u534e\u533a\u9996\u4f8b\u60a3\u8005\u5165\u7ec4\u3002<\/p>\n
\u4e8e2022\u5e74\u4e0a\u534a\u5e74\u7684\u533b\u5b66\u4f1a\u8bae\u4e0a\u63d0\u4f9bKRYSTAL-1 2\u671f\u6ce8\u518c\u6027\u7814\u7a76\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u961f\u5217\u7684\u4e34\u5e8a\u6570\u636e\u66f4\u65b0\u3002<\/p>\n
\u6709\u671b\u83b7\u5f97FDA\u5ba1\u6279\u5e76\u5728\u7f8e\u56fd\u5546\u4e1a\u4e0a\u5e02\uff0cPDUFA\u7684\u65e5\u671f\u4e3a2022\u5e7412\u670814\u65e5\u3002<\/p>\n
Bemarituzumab<\/b><\/p>\n
Bemarituzumab\u662f\u4e00\u6b3e\u540c\u7c7b\u9996\u521b\u6297\u4f53\uff0c\u4f5c\u4e3a\u9488\u5bf9FGFR2b\u8fc7\u5ea6\u8868\u8fbe\u7684\u80bf\u7624\u9776\u5411\u7597\u6cd5\uff0c\u6b63\u5728\u8fdb\u884c\u9488\u5bf9\u80c3\u764c\u53ca\u80c3\u98df\u7ba1\u4ea4\u754c\u90e8\u764c\u7684\u5f00\u53d1\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
\u518d\u9f0e\u533b\u836f\u5408\u4f5c\u4f19\u4f34\u5b89\u8fdb\u5df2\u542f\u52a8bemarituzumab\u7528\u4e8e\u4e00\u7ebf\u665a\u671f\u80c3\u764c\u548cGEJ\u764c\u7684\u4e24\u98793\u671f\u6ce8\u518c\u7814\u7a76\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u7b2c\u56db\u5b63\u5ea6\u5728\u4e2d\u56fd\u542f\u52a8\u4e00\u9879\u8bc4\u4f30bemarituzumab\u7528\u4e8e\u4e00\u7ebf\u665a\u671f\u80c3\u764c\u548cGEJ\u764c\u7684\u6ce8\u518c\u6027\u7814\u7a76\u3002<\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e00\u5b63\u5ea6\uff0c\u542f\u52a8bemarituzumab\u5355\u836f\u53ca\u8054\u5408\u5316\u7597\u6cbb\u7597\u665a\u671f\u96be\u6cbb\u6027\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u76841b\u671f\u63a2\u7d22\u7814\u7a76\u3002\u6b63\u8ba1\u5212\u9488\u5bf9\u5176\u5b83\u5b9e\u4f53\u7624\u5f00\u5c55\u63a2\u7d22\u7814\u7a76\u3002<\/p>\n
Odronextamab<\/b><\/p>\n
Odronextamab\u662f\u4e00\u6b3e\u53cc\u7279\u5f02\u6027\u6297\u4f53\uff0c\u65e8\u5728\u901a\u8fc7\u8fde\u63a5\u5e76\u6d3b\u5316\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\uff08\u7ed3\u5408CD3\uff09\u53ca\u6dcb\u5df4\u7624\u7ec6\u80de\uff08\u7ed3\u5408CD20\uff09\uff0c\u89e6\u53d1\u6297\u80bf\u7624\u4f5c\u7528\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u5b8c\u6210B-NHL\u6f5c\u5728\u5173\u952e2\u671f\u7814\u7a76\u7684\u5165\u7ec4\u3002<\/p>\n
\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u5411FDA\u63d0\u4ea4\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\u3002<\/p>\n
\u4e8e2022\u5e74\u542f\u52a8\u76ae\u4e0b\u7ed9\u836f\u5242\u578b\u7814\u7a76\u30013\u671fOLYMPIA\u9879\u76ee\uff0c\u4ee5\u53ca\u4e0e\u5176\u5b83\u836f\u7269\u8054\u7528\u7684\u7814\u7a76\u3002<\/p>\n
Repotrectinib<\/b><\/p>\n
Repotrectinib\u662f\u65b0\u4e00\u4ee3\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242 (TKI) \uff0c\u80fd\u6709\u6548\u9776\u5411\u4f5c\u7528\u4e8eROS1\u53caTRK A\/B\/C \uff0c\u5bf9\u65e2\u5f80\u672a\u63a5\u53d7\u8fc7TKI\u6cbb\u7597\u6216TKI\u7ecf\u6cbb\u7684\u60a3\u8005\u5747\u6709\u6cbb\u7597\u6f5c\u529b\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2022\u5e742\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\u6388\u4e88repotrectinib\u7a81\u7834\u6027\u6cbb\u7597\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u672a\u63a5\u53d7\u8fc7ROS1 TKI\u6cbb\u7597\u7684ROS1\u9633\u6027\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u3002<\/p>\n
2022\u5e741\u6708\uff0cTRIDENT-1\u7814\u7a761\u671f\u90e8\u5206\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u65e2\u5f80\u672a\u63a5\u53d7\u8fc7TKI\u6cbb\u7597\u7684ROS1\u9633\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684\u6570\u636e\u7ee7\u7eed\u663e\u793arepotrectinib\u5177\u6709\u540c\u7c7b\u6700\u4f18\u6f5c\u529b\u3002 <\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u62a5\u544aTRIDENT-1\u7814\u7a76\u4e2d\u6240\u6709ROS1\u9633\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u961f\u5217\u7684\u4e3b\u8981\u76f2\u6001\u72ec\u7acb\u4e2d\u5fc3\u5ba1\u67e5\uff08BICR\uff09\u7ed3\u679c\uff08\u5305\u62ec\u5ba2\u89c2\u7f13\u89e3\u7387\u548c\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff09\u3002<\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684NDA\u9012\u4ea4\u524d\u4f1a\u8bae\u4e0a\u4e0eFDA\u8ba8\u8bba\u4e3b\u8981BICR\u6570\u636e\u3002<\/p>\n
\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u63d0\u4f9bTRIDENT-1\u7814\u7a76\u4e2dNTRK\u9633\u6027\u665a\u671f\u5b9e\u4f53\u7624\u961f\u5217\u7684\u4e34\u5e8a\u6570\u636e\u66f4\u65b0\u3002<\/p>\n
CLN-081<\/b><\/p>\n
CLN-081\u662f\u4e00\u6b3e\u53e3\u670d\u5c0f\u5206\u5b50\u836f\u7269\uff0c\u7531Cullinan Oncology, Inc.\u5b50\u516c\u53f8Cullinan Pearl\u5f00\u53d1\u7684\u4e0d\u53ef\u9006\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u6291\u5236\u5242\uff0c\u53ef\u4ee5\u9009\u62e9\u6027\u5730\u9776\u5411\u4f5c\u7528\u4e8eEGFR\u5916\u663e\u5b5020\u63d2\u5165\u7a81\u53d8\uff0c\u540c\u65f6\u907f\u8fc7\u91ce\u751f\u578bEGFR\u7ec6\u80de\uff0c\u7528\u4e8e\u6cbb\u7597EGFR\u5916\u663e\u5b5020\u63d2\u5165\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u3002 <\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2022\u5e741\u6708\uff0cFDA\u6388\u4e88CLN-081\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597\u643a\u5e26EGFR\u5916\u663e\u5b5020\u63d2\u5165\u7a81\u53d8\u4e14\u65e2\u5f80\u63a5\u53d7\u8fc7\u542b\u94c2\u7cfb\u7edf\u5316\u7597\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u975e\u5c0f\u7ec6\u80de\u80ba\u764c2a\u671f\u6f5c\u5728\u5173\u952e\u7814\u7a76\u5b8c\u6210\u5927\u4e2d\u534e\u533a\u9996\u4f8b\u60a3\u8005\u5165\u7ec4\u3002<\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u63d0\u4f9b\u6ce8\u518c\u4e8b\u52a1\u66f4\u65b0\u3002<\/p>\n
Elzovantinib (TPX-0022)<\/b><\/p>\n
Elzovantinib\u662f\u4e00\u6b3e\u53e3\u670d\u591a\u9776\u70b9\u6fc0\u9176\u6291\u5236\u5242\uff0c\u5177\u6709\u65b0\u578b\u4e09\u7ef4\u5927\u73af\u7ed3\u6784\uff0c\u53ef\u6291\u5236MET\u3001CSF1R\uff08\u96c6\u843d\u523a\u6fc0\u56e0\u5b501\u53d7\u4f53\uff09\u53caSRC\u6fc0\u9176\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2022\u5e741\u6708\uff0cFDA\u6279\u51c6elzovantinib\u548c\u963f\u7f8e\u66ff\u5c3c\u8054\u5408\u7528\u4e8e\u6cbb\u7597EGFR\u7a81\u53d8MET\u6269\u589e\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u65b0\u836f\u4e34\u5e8a\u7814\u7a76\uff08IND\uff09\u7533\u8bf7\u7684\u6279\u51c6\u3002 <\/p>\n
2021\u5e7412\u6708\uff0cFDA\u540c\u610f\u5728\u786e\u5b9a\u63a8\u8350\u76842\u671f\u5242\u91cf\u540e\uff0c\u7ee7\u7eed\u8fdb\u884cSHIELD-1\u7684\u6f5c\u5728\u6ce8\u518c\u60272\u671fMET\u6269\u589e\u80c3\u764c\/GEJ\u764c\u6269\u5c55\u961f\u5217\u7684\u7814\u7a76\u3002\u540e\u7eed\u5c06\u6839\u636eFDA\u7684\u6307\u5bfc\uff0c\u5411FDA\u63d0\u4ea42\u671f\u7814\u7a76\u6570\u636e\uff0c\u5e76\u8ba8\u8bba\u8be5\u7814\u7a76\u662f\u5426\u6709\u53ef\u80fd\u4f5c\u4e3a\u6ce8\u518c\u6027\u7814\u7a76\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u63d0\u4f9b1\u671fSHIELD-1\u7814\u7a76\u7684\u4e34\u5e8a\u6570\u636e\u66f4\u65b0\u3002<\/p>\n
\u89c6FDA\u5bf9\u4e2d\u7b49\u5242\u91cf\u6c34\u5e73\u6570\u636e\u7684\u53cd\u9988\u800c\u5b9a\uff0c\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u542f\u52a8SHIELD-1\u7814\u7a76\u76842\u671f\u90e8\u5206\u3002 <\/p>\n
\u4e8e2022\u5e74\u5e74\u4e2d\u542f\u52a8elzovantinib\u548c\u963f\u7f8e\u66ff\u5c3c\u8054\u5408\u7528\u836f\u76841b\/2\u671fSHIELD-2\u7814\u7a76\u3002<\/p>\n
\u9ea6\u7518\u4e50<\/b>®<\/b>\uff08\u9a6c\u5409\u59a5\u6614\u5355\u6297\uff09<\/b><\/p>\n
\u9ea6\u7518\u4e50\u662f\u4e00\u6b3e\u9776\u5411\u4f5c\u7528\u4e8e\u4eba\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f532 (HER2) \u7684Fc\u6bb5\u4f18\u5316\u7684\u5355\u514b\u9686\u6297\u4f53\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9<\/b>\/<\/b>\u8fdb\u5c55\uff1a<\/b><\/p>\n
2022\u5e741\u6708\uff0cNMPA\u53d7\u7406\u9a6c\u5409\u59a5\u6614\u5355\u6297\u6cbb\u7597\u7ecf\u6cbb\u8f6c\u79fb\u6027HER2\u9633\u6027\u4e73\u817a\u764c\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n
\u6839\u636e\u6b64\u524d\u62ab\u9732\u53ca\u5bf9\u4e34\u5e8a\u6570\u636e\u7684\u8bc4\u4f30\u548c\u5916\u90e8\u73af\u5883\u7684\u53d8\u5316\uff0c\u6211\u4eec\u5df2\u7ecf\u51b3\u5b9a\u4e0d\u518d\u53c2\u52a02\/3\u671fMAHOGANY\u7814\u7a76\u7684\u961f\u5217B\u90e8\u5206\u30022021\u5e7411\u6708\uff0cMacroGenics\u5ba3\u5e03\u51b3\u5b9a\u4e2d\u6b62MAHOGANY\u7814\u7a76\u961f\u5217A\u90e8\u5206\u7684\u60a3\u8005\u5165\u7ec4\u3002<\/p>\n
Tebotelimab<\/b><\/p>\n
Tebotelimab\u662f\u4e00\u6b3e\u9776\u5411\u4f5c\u7528\u4e8ePD-1\u53caLAG-3\u7684\u5904\u4e8e\u7814\u7a76\u9636\u6bb5\u7684\u3001\u540c\u7c7b\u9996\u521b\u3001\u53cc\u7279\u5f02\u6027\u56db\u4ef7DART\u5206\u5b50\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u8fdb\u5c55\uff1a<\/b><\/p>\n
\u6839\u636e\u6b64\u524d\u62ab\u9732\u53ca\u5bf9\u4e34\u5e8a\u6570\u636e\u7684\u8bc4\u4f30\uff0c\u518d\u9f0e\u533b\u836f\u5df2\u51b3\u5b9a\u7ec8\u6b62\u5176\u53d1\u8d77\u7684tebotelimab\u7528\u4e8e\u9ed1\u8272\u7d20\u7624\u548c\u809d\u7ec6\u80de\u764c\u7684\u7814\u7a76\uff0c\u4ee5\u53catebotelimab\u548c\u5c3c\u62c9\u5e15\u5229\u8054\u7528\u7684\u7bee\u5b50\u7814\u7a76\u3002<\/p>\n
BLU-945<\/b><\/p>\n
BLU-945\u662f\u4e00\u6b3e\u9009\u62e9\u6027\u3001\u5f3a\u6548\u7684EGFR\u6291\u5236\u5242\uff0c\u53ef\u4ee5\u6291\u5236L858R\u6d3b\u5316\u7a81\u53d8\u621619\u5916\u663e\u5b50\u7f3a\u5931\u7a81\u53d8\u4f34\u53d1\u83b7\u5f97\u6027T790M\u548cC797S\u7a81\u53d8\uff0c\u8fd9\u4e9b\u7a81\u53d8\u5206\u522b\u662f\u7b2c\u4e00\u4ee3EGFR\u6291\u5236\u5242\u548c\u5965\u5e0c\u66ff\u5c3c\u5e38\u89c1\u7684\u9776\u5411\u8010\u836f\u7a81\u53d8\u3002BLU-945\u6709\u671b\u7528\u4e8e\u6cbb\u7597EGFR\u9a71\u52a8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
\u5728\u82f1\u56fd\u80f8\u79d1\u80bf\u7624\u5b66\u7ec4\u5e74\u4f1a\u4e0a\u53d1\u5e03\u4e86\u65b0\u7684\u4e34\u5e8a\u524d\u6570\u636e\uff0c\u652f\u6301 BLU-701\u548cBLU-945\u8054\u5408\u6cbb\u7597EGFR\u9a71\u52a8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u5f00\u53d1\u3002<\/p>\n
\u7f8e\u56fd\u764c\u75c7\u7814\u7a76\u534f\u4f1a (AACR) \u5e74\u4f1a\u5df2\u7ecf\u63a5\u53d7\u591a\u9879\u6458\u8981\uff0c\u5305\u62ecBLU-945\u7528\u4e8e\u6cbb\u7597EGFR\u9a71\u52a8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u76841\/2\u671fSYMPHONY\u7814\u7a76\u521d\u6b65\u7684\u5242\u91cf\u9012\u589e\u6570\u636e\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u516c\u5e03BLU-945\u7528\u4e8e\u6cbb\u7597EGFR\u9a71\u52a8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u76841\/2\u671fSYMPHONY\u7814\u7a76\u521d\u6b65\u6570\u636e\u3002<\/p>\n
BLU-701<\/b><\/p>\n
BLU-701\u662f\u4e00\u6b3e\u9009\u62e9\u6027\u3001\u5f3a\u6548\u7684EGFR\u6291\u5236\u5242\uff0c\u53ef\u4ee5\u6291\u5236L858R\u6d3b\u5316\u7a81\u53d8\u621619\u5916\u663e\u5b50\u7f3a\u5931\u7a81\u53d8\u4f34\u6709\u83b7\u5f97\u6027C797S\u7a81\u53d8\uff0c\u8fd9\u4e9b\u7a81\u53d8\u662f\u5965\u5e0c\u66ff\u5c3c\u5e38\u89c1\u7684\u9776\u5411\u8010\u836f\u7a81\u53d8\u3002BLU-701\u6709\u671b\u7528\u4e8e\u6cbb\u7597EGFR\u9a71\u52a8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
BLU-701\u6cbb\u7597EGFR\u9a71\u52a8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u76841\/2\u671fHARMONY\u7814\u7a76\u9996\u4f4d\u60a3\u8005\u63a5\u53d7\u6cbb\u7597\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u516c\u5e03BLU-701\u6cbb\u7597EGFR\u9a71\u52a8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c1\/2\u671fHARMONY\u7814\u7a76\u521d\u6b65\u6570\u636e\u3002<\/p>\n
Simurosertib, ZL-2309<\/b><\/p>\n
(CDC7<\/b>\u6291\u5236\u5242\uff0c\u5168\u7403\u6743\u5229<\/b>)<\/b><\/p>\n
Simurosertib\uff08\u53c8\u79f0\u4e3aZL-2309\uff09\u662f\u4e00\u6b3e\u53ef\u80fd\u6210\u4e3a\u540c\u7c7b\u9996\u521b\u7684\u53e3\u670d\u3001\u9009\u62e9\u6027CDC7\u6291\u5236\u5242\u3002CDC7\u662f\u4e00\u79cd\u86cb\u767d\u6fc0\u9176\uff0c\u5728DNA\u590d\u5236\u548c\u7ed5\u8fc7DNA\u635f\u4f24\u53cd\u5e94\u4e2d\u8d77\u5173\u952e\u4f5c\u7528\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u542f\u52a8\u751f\u7269\u6807\u8bb0\u7269\u9a71\u52a8\u76842\u671f\u6982\u5ff5\u9a8c\u8bc1\u7814\u7a76\u3002<\/p>\n
ZL-1201 <\/b><\/p>\n
(CD47 <\/b>\u6291\u5236\u5242\uff0c\u5168\u7403\u6743\u5229<\/b>)<\/b><\/p>\n
ZL-1201\u662f\u4e00\u6b3e\u7ecf\u5de5\u7a0b\u5316\u6539\u9020\u964d\u4f4e\u4e86\u6548\u5e94\u529f\u80fd\uff0c\u7279\u5f02\u6027\u9776\u5411CD47\u7684\u4eba\u6e90\u5316IgG4\u5355\u514b\u9686\u6297\u4f53\u3002ZL-1201\u5355\u836f\u548c\u8054\u5408\u6cbb\u7597\u7684\u6cbb\u7597\u6f5c\u529b\uff0c\u5c06\u5728\u5b9e\u4f53\u7624\u548c\u6076\u6027\u8840\u6db2\u80bf\u7624\u4e2d\u8fdb\u884c\u8bc4\u4f30\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u6b63\u5728\u8fdb\u884c\u76841\u671f\u4e34\u5e8a\u7814\u7a76\u5c06\u4e8e2022\u5e74\u5e74\u4e2d\u786e\u5b9a2\u671f\u63a8\u8350\u5242\u91cf\u3002<\/p>\n
\u57282022\u5e74AACR\u5e74\u4f1a\u4e0a\u516c\u5e03ZL-1201\u8054\u5408\u6807\u51c6\u6297\u4f53\u6cbb\u7597\u65b9\u6848\u6cbb\u7597\u8840\u6db2\u80bf\u7624\u548c\u5b9e\u4f53\u7624\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u6570\u636e\u3002<\/p>\n
\u5176\u5b83\u5185\u90e8\u7814\u53d1\u9879\u76ee\uff08\u5168\u7403\u6743\u5229\uff09<\/b><\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u57282022\u5e74AACR\u5e74\u4f1a\u4e0a\u516c\u5e03ZL-1211 (Claudin18.2)\u3001ZL-2201 (DNA-PK) \u548cZL-1218 (CCR8) \u7684\u4e34\u5e8a\u524d\u6570\u636e\u3002<\/p>\n
\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u9886\u57df<\/b><\/p>\n
VYVGART™<\/b>\uff08<\/b>Efgartigimod<\/b>\uff09<\/b><\/p>\n
Efgartigimod\u662f\u4e00\u6b3e\u6297\u4f53\u7247\u6bb5\uff0c\u65e8\u5728\u51cf\u5c11\u81f4\u75c5\u6027\u514d\u75ab\u7403\u86cb\u767dG\uff08IgG\uff09\u81ea\u8eab\u6297\u4f53\u5e76\u963b\u65adIgG\u5faa\u73af\u5229\u7528\u8fc7\u7a0b\u3002Efgartigimod\u4e0e\u65b0\u751f\u513fFc\u53d7\u4f53\uff08FcRn\uff09\u7ed3\u5408\uff0c\u8be5\u53d7\u4f53\u5728\u5168\u8eab\u90fd\u6709\u5e7f\u6cdb\u8868\u8fbe\uff0c\u5728\u963b\u6b62IgG\u964d\u89e3\u7684\u8fc7\u7a0b\u4e2d\u53d1\u6325\u7740\u6838\u5fc3\u4f5c\u7528\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2022\u5e742\u6708\uff0cefgartigimod\u7528\u4e8e\u6cbb\u7597\u5bfb\u5e38\u578b\u5929\u75b1\u75ae\uff08PV\uff09\u6216\u843d\u53f6\u578b\u5929\u75b1\u75ae\uff08PF\uff09\u7684\u5168\u7403\u6ce8\u518c\u60273\u671fADDRESS\u7814\u7a76\uff0c\u4ee5\u53ca\u7528\u4e8e\u6cbb\u7597ITP\u7684\u5168\u7403\u6ce8\u518c\u60273\u671fADVANCE-SC\u7814\u7a76\uff0c\u5206\u522b\u5b8c\u6210\u6700\u540e\u4e00\u4f8b\u4e2d\u56fd\u60a3\u8005\u5165\u7ec4\u3002<\/p>\n
2022\u5e741\u6708\uff0cVYVGART\u5728\u65e5\u672c\u83b7\u6279\u7528\u4e8e\u6cbb\u7597gMG\uff0c\u8fd9\u662f\u76ee\u524d\u5728\u65e5\u672c\u83b7\u6279\u7684\u9996\u6b3e\u4e5f\u662f\u552f\u4e00\u4e00\u6b3eFcRn\u62ee\u6297\u5242\u3002<\/p>\n
2021\u5e7412\u6708\uff0cFDA\u6279\u51c6VYVGART\u7528\u4e8e\u6cbb\u7597\u6297\u4e59\u9170\u80c6\u78b1\u53d7\u4f53\uff08AChR\uff09\u6297\u4f53\u9633\u6027\u7684gMG\u6210\u4eba\u60a3\u8005\u3002\u7531\u6b64\uff0cVYVGART\u6210\u4e3aFDA\u6279\u51c6\u7684\u9996\u6b3e\u4e5f\u662f\u76ee\u524d\u552f\u4e00\u4e00\u6b3eFcRn\u62ee\u6297\u5242\u3002<\/p>\n
2021\u5e74\u5e74\u5e95\uff0c\u542f\u52a8\u76ae\u4e0b\u6ce8\u5c04efgartigimod\u6cbb\u7597\u5927\u75b1\u6027\u7c7b\u5929\u75b1\u75ae\u7684\u6ce8\u518c\u6027\u7814\u7a76\u3002<\/p>\n
2021\u5e7411\u6708\uff0cefgartigimod\u6cbb\u7597CIDP\u60a3\u8005\u7684\u5168\u7403\u6ce8\u518c\u6027\u7814\u7a76ADHERE\u5b8c\u6210\u5927\u4e2d\u534e\u533a\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/p>\n
2021\u5e7411\u6708\uff0cefgartigimod\u6cbb\u7597PV\/PF\u60a3\u8005\u7684\u5168\u7403\u6ce8\u518c\u60273\u671f\u7814\u7a76ADDRESS\u5b8c\u6210\u5927\u4e2d\u534e\u533a\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/p>\n
2021\u5e7411\u6708\uff0cefgartigimod\u6cbb\u7597ITP\u60a3\u8005\u7684\u5168\u7403\u6ce8\u518c\u60273\u671f\u7814\u7a76ADVANCE-SC\u5b8c\u6210\u5927\u4e2d\u534e\u533a\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u542f\u52a8\u65b0\u7684\u6982\u5ff5\u9a8c\u8bc1\u7814\u7a76\uff0c\u5e76\u4e0eargenx\u5408\u4f5c\u63a2\u7d22\u548c\u63a8\u8fdb\u5176\u5b83\u9002\u5e94\u8bc1\u7684\u7814\u7a76\u3002<\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u542f\u52a8efgartigimod\u76ae\u4e0b\u6ce8\u5c04\u5242\u578b\u6cbb\u7597\u7279\u53d1\u6027\u708e\u6027\u808c\u75c5\uff08\u808c\u708e\uff09\u7684\u6ce8\u518c\u6027\u7814\u7a76\u3002\u8ba1\u5212\u5bf9\u6bcf\u4e2a\u4e9a\u578b\uff08\u514d\u75ab\u4ecb\u5bfc\u574f\u6b7b\u6027\u808c\u75c5\u3001\u6297\u5408\u6210\u9176\u6297\u4f53\u7efc\u5408\u5f81\u548c\u76ae\u808c\u708e\uff09\u7684\u524d40\u540d\u60a3\u8005\u7684\u6570\u636e\u8fdb\u884c\u4e2d\u671f\u5206\u6790\u3002<\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u62a5\u544a\u76ae\u4e0b\u6ce8\u5c04efgartigimod\u6cbb\u7597gMG\u7684\u4e3b\u8981\u6570\u636e\u3002<\/p>\n
\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u62a5\u544a\u9759\u8109\u6ce8\u5c04efgartigimod\u6cbb\u7597ITP\u7684\u4e3b\u8981\u6570\u636e\u3002<\/p>\n
\u4e8e2022\u5e74\u7b2c\u56db\u5b63\u5ea6\u62a5\u544a\u76ae\u4e0b\u6ce8\u5c04efgartigimod\u6cbb\u7597PV\/PF\u7684\u4e3b\u8981\u6570\u636e\u3002<\/p>\n
\u542f\u52a8\u9488\u5bf9\u4e24\u79cd\u65b0\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u6982\u5ff5\u9a8c\u8bc1\u7814\u7a76\uff1a\u539f\u53d1\u6027\u5e72\u71e5\u7efc\u5408\u5f81\uff082022\u5e74\u4e0b\u534a\u5e74\uff09\u548c\u65b0\u51a0\u75c5\u6bd2\u4ecb\u5bfc\u7684\u4f53\u4f4d\u6027\u76f4\u7acb\u6027\u5fc3\u52a8\u8fc7\u901f\u7efc\u5408\u5f81\uff082022\u5e74\u5e74\u4e2d\uff09\u3002<\/p>\n
ZL-1102<\/b><\/p>\n
\uff08<\/b>IL-17<\/b>\u5168\u4eba\u6e90<\/b>VH<\/b>\u6297\u4f53\u7247\u6bb5\uff0c\u5168\u7403\u6743\u5229\uff09<\/b><\/p>\n
ZL-1102\u662f\u4e00\u6b3e\u65b0\u578b\u5168\u4eba\u6e90VH\u6297\u4f53\u7247\u6bb5 (Humabody®)\uff0c\u9776\u5411\u4f5c\u7528\u4e8eIL-17A\u7ec6\u80de\u56e0\u5b50\uff0c\u5177\u6709\u9ad8\u4eb2\u548c\u529b\u548c\u6d3b\u6027\u3002\u6709\u522b\u4e8e\u5176\u5b83\u6297IL-17\u4ea7\u54c1\uff0cZL-1102\u6b63\u5728\u5f00\u53d1\u7528\u4e8e\u8f7b\u4e2d\u5ea6\u6162\u6027\u6591\u5757\u72b6\u94f6\u5c51\u75c5\uff08CPP\uff09\u7684\u5c40\u90e8\u6cbb\u7597\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
\u8fd1\u671f\u5bf9ZL-1102\u7684\u8f6c\u5f55\u7ec4\u5206\u6790\u663e\u793a\u51fa\u660e\u663e\u7684\u5dee\u522b\u6548\u5e94\uff0c\u5176\u4e0b\u8c03\u57fa\u56e0\u5bcc\u96c6\u5728\u514d\u75ab\u53cd\u5e94\u9014\u5f84\u4e14K16\u6807\u8bb0\u7269\u8868\u8fbe\u51cf\u5c11\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u4e0b\u534a\u5e74\u542f\u52a8CPP\u7684\u5168\u74032\u671f\u7814\u7a76\u3002<\/p>\n
\u6297\u611f\u67d3\u9886\u57df<\/b><\/p>\n
\u7ebd\u518d\u4e50<\/b>®<\/b>\uff08\u7532\u82ef\u78fa\u9178\u5965\u9a6c\u73af\u7d20\uff09<\/b><\/p>\n
\u7ebd\u518d\u4e50\u662f\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u6216\u9759\u8109\u4f7f\u7528\u7684\u6297\u751f\u7d20\uff0c\u7528\u4e8e\u6cbb\u7597\u793e\u533a\u83b7\u5f97\u6027\u7ec6\u83cc\u6027\u80ba\u708e\uff08CABP\uff09\u53ca\u6025\u6027\u7ec6\u83cc\u6027\u76ae\u80a4\u548c\u76ae\u80a4\u7ed3\u6784\u611f\u67d3\uff08ABSSSI\uff09\u7684\u6210\u4eba\u60a3\u8005\u3002<\/p>\n
\u8fd1\u671f\u4ea7\u54c1\u4eae\u70b9\uff1a<\/b><\/p>\n
2021\u5e7412\u6708\uff0c\u7ebd\u518d\u4e50\u4f5c\u4e3a1\u7c7b\u521b\u65b0\u836f\u7269\u7528\u4e8e\u6cbb\u7597CABP\u548cABSSSI\u83b7\u5f97NMPA\u6279\u51c6\u5e76\u5546\u4e1a\u4e0a\u5e02\u3002\u8be5\u4ea7\u54c1\u5728\u4e2d\u56fd\u672c\u571f\u751f\u4ea7\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e89\u53d6\u7ebd\u518d\u4e50CABP\u548cABSSSI\u9002\u5e94\u8bc1\u7eb3\u5165NRDL\u3002<\/p>\n
\u8212\u5df4\u5766<\/b>-Durlobactam<\/b><\/p>\n
\uff08<\/b>SUL-DUR<\/b>\uff0c\u4e9a\u592a\u5730\u533a\u6743\u76ca\uff09<\/b><\/p>\n
\u8212\u5df4\u5766-Durlobactam\u662f\u4e00\u6b3e\u03b2-\u5185\u9170\u80fa\u2571\u03b2-\u5185\u9170\u80fa\u9176\u6291\u5236\u5242\u7684\u7ec4\u5408\u578b\u65b0\u836f\uff0c\u5bf9\u4e8e\u5305\u62ec\u78b3\u9752\u9709\u70ef\u8010\u836f\u83cc\u682a\u5728\u5185\u7684\u9c8d\u66fc\u4e0d\u52a8\u6746\u83cc\u5177\u6709\u72ec\u7279\u6d3b\u6027\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u4e8e2022\u5e74\u7b2c\u56db\u5b63\u5ea6\u5411NMPA\u63d0\u4ea4\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n
\u4e8e2022\u5e74\u5e74\u4e2d\u5411FDA\u63d0\u4ea4\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n
\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u9886\u57df<\/b><\/p>\n
KarXT<\/b><\/p>\n
KarXT\u5c06\u65b0\u578b\u6bd2\u8548\u78b1\u6fc0\u52a8\u5242\u546b\u8bfa\u7f8e\u6797\u4e0e\u5df2\u83b7\u6279\u7684\u6bd2\u8548\u78b1\u62ee\u6297\u5242\u66f2\u53f8\u6c2f\u94f5\u7ed3\u5408\uff0c\u4f18\u5148\u6fc0\u6d3b\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u4e2d\u7684\u6bd2\u8548\u78b1\u53d7\u4f53\uff0c\u6709\u671b\u7528\u4e8e\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u548c\u75f4\u5446\u76f8\u5173\u7684\u7cbe\u795e\u75c5\u6027\u969c\u788d\u3002<\/p>\n
2022<\/b>\u5e74\u9884\u671f\u91cc\u7a0b\u7891\uff1a<\/b><\/p>\n
\u542f\u52a8\u6865\u63a5\u7814\u7a76\u3002<\/p>\n
\u4e8e2022\u5e74\u4e0a\u534a\u5e74\u516c\u5e03\u9488\u5bf9\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7cbe\u795e\u75c5\u6027\u969c\u788d\u76843\u671f\u8ba1\u5212\u7684\u8be6\u60c5\uff0c\u5e76\u4e8e2022\u5e74\u5e74\u4e2d\u542f\u52a8\u76f8\u5173\u7814\u7a76\u3002<\/p>\n
\u4e8e2022\u5e74\u5e74\u4e2d\u62a5\u544a3\u671fEMERGENT-2\u7814\u7a76\u7684\u4e3b\u8981\u6570\u636e\u3002<\/p>\n
\u516c\u53f8\u6700\u65b0\u52a8\u6001<\/b><\/p>\n
2022\u5e742\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5ba3\u5e03\u5c06\u5c31\u4e00\u9879\u666e\u901a\u80a1\u80a1\u4efd\u62c6\u7ec6\u7684\u63d0\u6848\u5bfb\u6c42\u80a1\u4e1c\u7684\u6279\u51c6\u3002\u6839\u636e\u8fd9\u4e00\u63d0\u6848\uff0c\u6bcf\u80a1\u5df2\u53d1\u884c\u6216\u672a\u53d1\u884c\u7684\u666e\u901a\u80a1\u5c06\u88ab\u62c6\u7ec6\u4e3a\u5341\u80a1\u666e\u901a\u80a1\u3002\u516c\u53f8\u76f8\u4fe1\uff0c\u8fd9\u5c06\u589e\u52a0\u666e\u901a\u80a1\u5728\u6e2f\u4ea4\u6240\u7684\u4ea4\u6613\u6d41\u52a8\u6027\uff0c\u964d\u4f4e\u6295\u8d44\u95e8\u69db\uff0c\u5438\u5f15\u66f4\u591a\u6295\u8d44\u8005\u4e70\u5356\u666e\u901a\u80a1\u3002\u518d\u9f0e\u533b\u836f\u7684\u6bcf\u80a1\u7f8e\u56fd\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u76ee\u524d\u4ee3\u8868\u83b7\u5f97\u4e00\u80a1\u7f34\u8db3\u666e\u901a\u80a1\u7684\u6743\u5229\u3002\u5982\u679c\u80a1\u4efd\u62c6\u7ec6\u7684\u63d0\u6848\u83b7\u6279\u751f\u6548\uff0c\u6bcf\u80a1\u7f8e\u56fd\u5b58\u6258\u80a1\u4efd\u5c06\u4ee3\u8868\u83b7\u5f97\u5341\u80a1\u7f34\u8db3\u666e\u901a\u80a1\u7684\u6743\u5229\u3002<\/p>\n
2021\u5e7412\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5ba3\u5e03\u64e2\u5347\u4efb\u6d77\u777f\u535a\u58eb\u4e3a\u603b\u88c1\uff0c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u3001\u81ea\u8eab\u514d\u75ab\u53ca\u6297\u611f\u67d3\u9886\u57df\u5168\u7403\u5f00\u53d1\u8d1f\u8d23\u4eba\u3002<\/p>\n
2021\u5e7411\u6708\uff0c\u518d\u9f0e\u533b\u836f\u5ba3\u5e03\u4efb\u547dRichard Gaynor\u535a\u58eb\u4e3a\u8463\u4e8b\u4f1a\u6210\u5458\u3002Gaynor\u535a\u58eb\u76ee\u524d\u62c5\u4efbBioNTech\u7f8e\u56fd\u7684\u603b\u88c1\u517c\u7814\u53d1\u4e3b\u7ba1\u3002<\/p>\n
\u518d\u9f0e\u533b\u836f\u4e0d\u65ad\u52a0\u5f3a\u548c\u58ee\u5927\u56e2\u961f\u30022021\u5e7411\u6708\u4ee5\u6765\u52a0\u5165\u7684\u65b0\u5458\u5de5\u5305\u62ec\u751f\u7269\u836f\u53d1\u73b0\u9ad8\u7ea7\u526f\u603b\u88c1 Linda Liu \u535a\u58eb\u3001\u8f6c\u5316\u533b\u5b66\u9ad8\u7ea7\u526f\u603b\u88c1Hua Gong\u535a\u58eb\uff0c\u4ee5\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u3001\u81ea\u8eab\u514d\u75ab\u53ca\u6297\u611f\u67d3\u9886\u57df\u9879\u76ee\u7ba1\u7406\u526f\u603b\u88c1Jing Cao\u535a\u58eb\u7b49\u3002<\/p>\n
2022\u5e741\u670831\u65e5\uff0c\u518d\u9f0e\u533b\u836f\u5171\u67091,951\u540d\u5168\u804c\u5458\u5de5\uff0c\u5176\u4e2d\u4ece\u4e8b\u7814\u53d1\u548c\u5546\u4e1a\u5316\u5c97\u4f4d\u7684\u5458\u5de5\u6570\u91cf\u5206\u522b\u4e3a788\u548c945\u3002<\/p>\n
2021<\/b>\u5e74\u5168\u5e74\u8d22\u52a1\u4e1a\u7ee9<\/b><\/p>\n
2021\u5e74\u5168\u5e74\u7684\u4ea7\u54c1\u51c0\u6536\u5165\u4e3a1.441\u4ebf\u7f8e\u5143\uff0c2020\u5e74\u540c\u671f\u6536\u5165\u4e3a4,900\u4e07\u7f8e\u5143\u3002\u5176\u4e2d\u5305\u62ec\u5219\u4e50\u9500\u552e\u6536\u51659,360\u4e07\u7f8e\u5143\uff082020\u5e74\u540c\u671f\u4e3a3,220\u4e07\u7f8e\u5143\uff09\u3001\u7231\u666e\u76fe\u9500\u552e\u6536\u51653,890\u4e07\u7f8e\u5143\uff082020\u5e74\u540c\u671f\u4e3a1,640\u4e07\u7f8e\u5143\uff09\u3001\u64ce\u4e50\u9500\u552e\u6536\u51651,160\u4e07\u7f8e\u5143\uff082020\u5e74\u540c\u671f\u4e3a40\u4e07\u7f8e\u5143\uff09\u3002\u6839\u636e\u653f\u7b56\u8981\u6c42\uff0c\u6211\u4eec\u4e8e2021\u5e74\u7b2c\u56db\u5b63\u5ea6\u5bf9\u6536\u5165\u8fdb\u884c\u4e86750\u4e07\u7f8e\u5143\u7684\u4e00\u6b21\u6027\u8c03\u51cf\uff0c\u4f5c\u4e3a\u5bf9\u4ecd\u5728\u5206\u9500\u6e20\u9053\u4e2d\u63092021\u5e74\u4ef7\u683c\u9500\u552e\u7684\u5219\u4e50\u7684\u4e00\u6b21\u6027\u8865\u507f\u3002<\/p>\n
2021\u5e74\u7814\u7a76\u4e0e\u5f00\u53d1\uff08\u7814\u53d1\uff09\u652f\u51fa\u4e3a5.733\u4ebf\u7f8e\u5143\uff0c2020\u5e74\u540c\u671f\u4e3a2.227\u4ebf\u7f8e\u5143\u30022021\u5e74\u7814\u53d1\u652f\u51fa\u7684\u589e\u52a0\u4e3b\u8981\u7531\u4e8e\u516b\u9879\u65b0\u7b7e\u7684\u8bb8\u53ef\u534f\u8bae\u7684\u9884\u4ed8\u6b3e\u3001\u6b63\u5728\u8fdb\u884c\u53ca\u65b0\u542f\u52a8\u7684\u540e\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u76f8\u5173\u8d39\u7528\u3001\u589e\u8058\u7814\u53d1\u4eba\u5458\u7684\u5de5\u8d44\u53ca\u5de5\u8d44\u76f8\u5173\u5f00\u652f\u589e\u52a0\u6240\u81f4\u3002\u4e0d\u5305\u62ec\u65b0\u7b7e\u8bb8\u53ef\u534f\u8bae\u7684\u9884\u4ed8\u6b3e\u5728\u5185\uff0c2021\u5e74\u6838\u5fc3\u7814\u53d1\u652f\u51fa\u4e3a2.52\u4ebf\u7f8e\u5143\uff0c2020\u5e74\u540c\u671f\u4e3a1.392\u4ebf\u7f8e\u5143\u3002<\/p>\n
2021\u5e74\u9500\u552e\u3001\u4e00\u822c\u53ca\u884c\u653f\uff08SG&A\uff09\u5f00\u652f\u4e3a2.188\u4ebf\u7f8e\u5143\uff0c2020\u5e74\u540c\u671f\u4e3a1.113\u4ebf\u7f8e\u5143\u3002\u589e\u52a0\u4e3b\u8981\u7531\u4e8e\u6269\u5927\u7684\u5546\u4e1a\u5316\u56e2\u961f\u7684\u5de5\u8d44\u53ca\u5de5\u8d44\u76f8\u5173\u5f00\u652f\u4ee5\u53ca\u518d\u9f0e\u533b\u836f\u6301\u7eed\u5728\u4e2d\u56fd\u6269\u5c55\u548c\u6295\u8d44\u5546\u4e1a\u7ecf\u8425\u7684\u76f8\u5173\u5f00\u652f\u6240\u81f4\uff0c\u9884\u8ba1\u672a\u6765\u51e0\u5e74\u5c06\u5927\u5e45\u589e\u957f\u3002<\/p>\n
2021\u5e74\u5168\u5e74\uff0c\u518d\u9f0e\u533b\u836f\u4e8f\u635f\u51c0\u989d\u4e3a7.045\u4ebf\u7f8e\u5143\uff08\u6216\u666e\u901a\u80a1\u4e1c\u5e94\u5360\u6bcf\u80a1\u4e8f\u635f\u4e3a7.58\u7f8e\u5143\uff09\uff0c2020\u5e74\u540c\u671f\u4e8f\u635f\u51c0\u989d\u4e3a2.689\u4ebf\u7f8e\u5143\uff08\u6216\u666e\u901a\u80a1\u4e1c\u5e94\u5360\u6bcf\u80a1\u4e8f\u635f\u4e3a3.46\u7f8e\u5143\uff09\u3002\u4e8f\u635f\u51c0\u989d\u7684\u589e\u52a0\u4e3b\u8981\u7531\u4e8e\u65b0\u5546\u52a1\u62d3\u5c55\u6d3b\u52a8\u7684\u76f8\u5173\u5f00\u652f\u6240\u81f4\u3002<\/p>\n
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