{"id":62563,"date":"2022-02-17T15:30:00","date_gmt":"2022-02-17T08:30:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022021715300062563"},"modified":"2022-02-17T17:59:43","modified_gmt":"2022-02-17T09:59:43","slug":"%e8%8b%b1%e7%9f%bd%e6%99%ba%e8%83%bd%e4%b8%8e%e5%a4%8d%e6%98%9f%e5%8c%bb%e8%8d%af%e8%be%be%e6%88%90%e6%88%98%e7%95%a5%e5%90%88%e4%bd%9c%e7%9a%84%e9%a6%96%e4%b8%aa%e9%87%8d%e5%a4%a7%e9%87%8c%e7%a8%8b","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022021715300062563","title":{"rendered":"\u82f1\u77fd\u667a\u80fd\u4e0e\u590d\u661f\u533b\u836f\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u7684\u9996\u4e2a\u91cd\u5927\u91cc\u7a0b\u7891\uff0c\u63d0\u540d\u9776\u5411CD47-SIRP\u03b1\u4fe1\u53f7\u901a\u8def\u7684\u5c0f\u5206\u5b50\u5316\u5408\u7269"},"content":{"rendered":"

\u4e0a\u6d77\u548c\u7ebd\u7ea62022\u5e742\u670817\u65e5 \/\u7f8e\u901a\u793e\/ — \u7531\u7aef\u5230\u7aef\u4eba\u5de5\u667a\u80fd\u9a71\u52a8\u7684\u836f\u7269\u7814\u53d1\u516c\u53f8\u82f1\u77fd\u667a\u80fd\uff08Insilico Medicine\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5df2\u5229\u7528\u5176\u81ea\u4e3b\u7814\u53d1\u7684\u4eba\u5de5\u667a\u80fd\u5e73\u53f0\uff0c\u63d0\u540d\u4e86\u9776\u5411QPCTL\u7684\u4e34\u5e8a\u524d\u5019\u9009\u5316\u5408\u7269\u7528\u4e8e\u521b\u65b0\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u8fd9\u662f\u82f1\u77fd\u667a\u80fd\u4e0e\u590d\u661f\u533b\u836f\u6218\u7565\u5408\u4f5c\u4e2d\u8fbe\u5230\u7684\u7b2c\u4e00\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\u3002\u82f1\u77fd\u667a\u80fd\u548c\u590d\u661f\u533b\u836f\u76ee\u524d\u6b63\u5728\u5171\u540c\u5f00\u5c55\u7528\u4e8e\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u7684\u7814\u7a76\uff0c\u4ee5\u5c3d\u5feb\u5c06\u8be5\u9879\u76ee\u63a8\u8fdb\u5230\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002<\/p>\n

\"Insilico<\/a>
Insilico Medicine achieves the first major milestone in collaboration with Fosun<\/span> <\/div>\n

ISM004-1057D \u662f\u82f1\u77fd\u667a\u80fd\u4e3a\u5408\u4f5c\u9879\u76ee\u5f00\u53d1\u7684\u9996\u4e2a\u4e34\u5e8a\u524d\u5019\u9009\u5316\u5408\u7269\uff0c\u662f\u4e00\u79cd\u9776\u5411QPCTL\u9776\u70b9\u7684\u6f5c\u5728\u5168\u7403\u9996\u521b\u5c0f\u5206\u5b50\u6291\u5236\u5242\u3002QPCTL\u5bf9CD47\u4e0a\u7126\u8c37\u6c28\u9178\u7684\u5f62\u6210\u8d77\u7740\u5173\u952e\u4f5c\u7528\uff0c\u8fd9\u4e00\u4fee\u9970\u662fCD47\u4e0e\u914d\u4f53SIRP\u03b1\u76f8\u4e92\u4f5c\u7528\u6240\u5fc5\u9700\u7684\u3002CD47\u662f\u4e00\u79cd\u5e7f\u6cdb\u8868\u8fbe\u4e8e\u591a\u79cd\u764c\u7ec6\u80de\u8868\u9762\u7684\u7cd6\u86cb\u767d\uff0c\u901a\u8fc7\u4e0e\u514d\u75ab\u7ec6\u80de\u8868\u9762SIRP\u03b1\u76f8\u4e92\u4f5c\u7528\uff0c\u91ca\u653e\u201c\u522b\u5403\u6211\u201d\u4fe1\u53f7\u6765\u4fdd\u62a4\u80bf\u7624\u7ec6\u80de\u514d\u53d7\u5929\u7136\u514d\u75ab\u7cfb\u7edf\u76d1\u89c6\u3002QPCTL \u5c0f\u5206\u5b50\u6291\u5236\u5242\u53ef\u6a21\u62df CD47 \u6297\u4f53\u7684\u6cbb\u7597\u6548\u679c\uff0c\u901a\u8fc7\u963b\u65ad\u8be5\u4fe1\u53f7\uff0c\u6765\u8fbe\u5230\u6297\u80bf\u7624\u6548\u679c\u3002<\/p>\n

\u5728\u4f53\u5185\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\uff0cISM004-1057D\u5728\u8840\u6db2\u80bf\u7624\u548c\u5b9e\u4f53\u80bf\u7624\u4e2d\u90fd\u663e\u793a\u51fa\u6297\u80bf\u7624\u7684\u529f\u6548\uff0c\u5e76\u8868\u73b0\u51fa\u826f\u597d\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u548c\u5b89\u5168\u6027\uff0c\u5177\u6709\u8fdb\u4e00\u6b65\u4e34\u5e8a\u5f00\u53d1\u4ef7\u503c\u3002\u6b64\u5916\uff0c\u4f5c\u4e3a\u9776\u5411QPCTL\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5242\uff0cISM004-1057D\u4e0d\u4ec5\u5177\u6709\u8f83\u9ad8\u7684\u80bf\u7624\u6e17\u900f\u6027\uff0c\u8fd8\u80fd\u964d\u4f4e\u8840\u6db2\u5b66\u6bd2\u526f\u4f5c\u7528\u907f\u514d\u6297\u539f\u6c89\u6ca1\uff0c\u800c\u8fd9\u6b63\u662f\u76ee\u524d\u5927\u591a\u6570CD47\u6297\u4f53\u836f\u7269\u5e38\u89c1\u7684\u526f\u4f5c\u7528\u3002<\/p>\n

\u590d\u661f\u533b\u836f\u6267\u884c\u603b\u88c1\u3001\u5168\u7403\u7814\u53d1\u4e2d\u5fc3\u603b\u88c1\u517c\u9996\u5e2d\u533b\u5b66\u5b98\u56de\u7231\u6c11\u535a\u58eb\u8868\u793a\uff1a<\/b>\u201c\u521b\u65b0\u4e00\u76f4\u662f\u590d\u661f\u533b\u836f\u6700\u6838\u5fc3\u7684\u53d1\u5c55\u9a71\u52a8\u529b\uff0c\u4eba\u5de5\u667a\u80fd\u5e73\u53f0\u4f5c\u4e3a\u53d8\u9769\u6027\u7684\u521b\u65b0\u6280\u672f\uff0c\u53ef\u5927\u5927\u63d0\u5347\u65b0\u836f\u521b\u65b0\u7684\u6548\u7387\uff0c\u4e3a\u533b\u836f\u521b\u65b0\u63d0\u4f9b\u6709\u529b\u652f\u6491\u3002\u671f\u5f85\u590d\u661f\u533b\u836f\u548c\u82f1\u77fd\u667a\u80fd\u7684\u7814\u53d1\u56e2\u961f\u80fd\u518d\u63a5\u518d\u5389\uff0c\u53d1\u6325\u5404\u81ea\u5728\u5728\u6280\u672f\u53ca\u4e34\u5e8a\u5f00\u53d1\u4e0a\u7684\u4f18\u52bf\uff0c\u60e0\u53ca\u5168\u7403\u66f4\u591a\u60a3\u8005\u3002\u201d<\/p>\n

\u82f1\u77fd\u667a\u80fd\u9996\u5e2d\u79d1\u5b66\u5b98\u4efb\u5cf0\u535a\u58eb\u8868\u793a\uff1a<\/b>\u201c\u4e0e\u590d\u661f\u533b\u836f\u7684\u5408\u4f5c\uff0c\u9ad8\u6548\u5730\u5b9e\u73b0\u4e86\u63d0\u540dQPCTL\u9879\u76ee\u4e34\u5e8a\u524d\u5019\u9009\u5316\u5408\u7269\u7684\u91cc\u7a0b\u7891\uff0c\u8fd9\u662f\u4e00\u6b21\u4e86\u4e0d\u8d77\u7684\u7ecf\u5386\u3002\u5728\u5408\u4f5c\u8fc7\u7a0b\u4e2d\uff0c\u590d\u661f\u533b\u836f\u7814\u53d1\u56e2\u961f\u7684\u4e13\u4e1a\u7cbe\u795e\u548c\u5728\u79d1\u5b66\u4e0e\u9879\u76ee\u7ba1\u7406\u65b9\u9762\u7684\u5f3a\u5927\u5b9e\u529b\u7ed9\u6211\u4eec\u7559\u4e0b\u4e86\u6df1\u523b\u7684\u5370\u8c61\u3002\u6211\u4eec\u671f\u5f85\u53cc\u65b9\u66f4\u7d27\u5bc6\u5730\u5408\u4f5c\uff0c\u5c3d\u65e9\u5c06\u8be5\u4e34\u5e8a\u524d\u5019\u9009\u5316\u5408\u7269\u63a8\u8fdb\u81f3\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002\u201d<\/p>\n

\u82f1\u77fd\u667a\u80fd\u5229\u7528\u5176\u7aef\u5230\u7aef\u4eba\u5de5\u667a\u80fd\u5e73\u53f0Pharma.AI\uff0c\u8be5\u5e73\u53f0\u5305\u62ec\u9776\u70b9\u8bc6\u522b\u5f15\u64cePandaOmics\u548c\u5c0f\u5206\u5b50\u751f\u6210\u5f15\u64ceChemistry42\u7b49\uff0c\u63d0\u51fa\u4e86\u80bf\u7624\u5b66\u7684\u9776\u70b9\u5047\u8bbe\uff0c\u5e76\u8bbe\u8ba1\u5177\u6709\u826f\u597d\u6210\u836f\u6027\u7684\u5316\u5408\u7269\u3002\u5728\u9879\u76ee\u542f\u52a8\u540e\u76849\u4e2a\u6708\u5185\uff0c\u82f1\u77fd\u667a\u80fd\u5408\u6210\u5e76\u6d4b\u8bd5\u4e8671\u4e2a\u5316\u5408\u7269\uff0c\u53d1\u73b0\u4e86\u8be5\u9879\u76ee\u7684\u4e34\u5e8a\u524d\u5019\u9009\u5316\u5408\u7269\u3002<\/p>\n

\u82f1\u77fd\u667a\u80fd\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u6267\u884c\u5b98<\/b>Alex Zhavoronkov<\/span><\/b>\u535a\u58eb\u8868\u793a\uff1a<\/b>\u201c\u4e16\u754c\u9700\u8981\u521b\u65b0\u7684\u3001\u6709\u6548\u7684first-in-class\u7684\u7597\u6cd5\u3002\u5728\u8fd9\u6b21\u4e0e\u590d\u661f\u533b\u836f\u7684\u5408\u4f5c\u4e2d\uff0c\u82f1\u77fd\u667a\u80fd\u5229\u7528\u4eba\u5de5\u667a\u80fd\u6280\u672f\u5237\u65b0\u4e86\u836f\u7269\u7814\u53d1\u7684\u901f\u5ea6\uff0c\u5e76\u5b9e\u73b0\u4e86\u9879\u76ee\u7684\u65b0\u9896\u6027\u3002\u6211\u5f88\u9ad8\u5174\u5728\u5ba3\u5e03\u5408\u4f5c\u540e\u4e0d\u523040 \u5929\u5185\uff0c\u7814\u53d1\u56e2\u961f\u6210\u529f\u63d0\u540d\u4e86QPCTL\u9879\u76ee\u7684\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269\uff0c\u5e76\u542f\u52a8\u4e86\u7528\u4e8e\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u62a5\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u3002\u6211\u4eec\u81f4\u529b\u4e8e\u4e3a\u6240\u6709\u53c2\u4e0e\u7684\u836f\u7269\u7814\u53d1\u9879\u76ee\u5e26\u6765\u901f\u5ea6\u3001\u8d28\u91cf\u548c\u521b\u65b0\uff0c\u5e76\u671f\u5f85\u5c3d\u5feb\u5c06\u5176\u63a8\u5411\u4e34\u5e8a\u5f00\u53d1\u3002\u201d<\/p>\n

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\u4e0a\u6d77\u548c\u7ebd\u7ea62022\u5e742\u670817\u65e5 \/\u7f8e\u901a\u793e\/ — \u7531\u7aef\u5230\u7aef\u4eba\u5de5\u667a\u80fd\u9a71\u52a8\u7684\u836f\u7269\u7814\u53d1\u516c\u53f8\u82f1\u77fd\u667a\u80fd\uff08Insilico 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