{"id":62362,"date":"2022-02-15T14:00:00","date_gmt":"2022-02-15T07:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022021514000062362"},"modified":"2022-02-15T17:59:34","modified_gmt":"2022-02-15T09:59:34","slug":"%e8%94%bc%e7%9d%a6%e5%8c%bb%e7%96%97%e5%ae%a3%e5%b8%83%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%97%e8%a7%86%e7%bd%91%e8%86%9c%e8%a1%80%e7%ae%a1%e7%96%be%e7%97%85%e7%9a%84%e6%96%b0%e5%9e%8b%e5%8f%8c%e7%89%b9","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022021514000062362","title":{"rendered":"\u853c\u7766\u533b\u7597\u5ba3\u5e03\u7528\u4e8e\u6cbb\u7597\u89c6\u7f51\u819c\u8840\u7ba1\u75be\u75c5\u7684\u65b0\u578b\u53cc\u7279\u5f02\u6027\u751f\u7269\u5206\u5b50 AM712 \u83b7 FDA \u7684 IND \u6279\u51c6"},"content":{"rendered":"

\u4e0a\u6d772022\u5e742\u670815\u65e5 \/\u7f8e\u901a\u793e\/ — \u81f4\u529b\u4e8e\u6ee1\u8db3\u5168\u7403\u773c\u79d1\u3001\u795e\u7ecf\u548c\u7cbe\u795e\u7cfb\u7edf\u75be\u75c5\u6cbb\u7597\u9700\u6c42\u7684\u4e34\u5e8a\u9636\u6bb5\u521b\u65b0\u751f\u7269\u533b\u836f\u516c\u53f8\u853c\u7766\u533b\u7597\u4eca\u5929\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40 (\u4ee5\u4e0b\u7b80\u79f0“FDA”) \u5df2\u6279\u51c6\u5176 AM712 (ASKG712) \u7684\u4e34\u5e8a\u5f00\u53d1\u65b0\u836f\u7814\u7a76 (IND) \u7533\u8bf7\u3002AM712 \u662f\u4e00\u6b3e\u65b0\u578b\u53cc\u7279\u5f02\u6027\u751f\u7269\u5206\u5b50\uff0c\u80fd\u591f\u540c\u65f6\u963b\u65ad\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50 (VEGF) \u548c\u8840\u7ba1\u751f\u6210\u7d20-2 (Ang-2)\uff0c\u6cbb\u7597\u89c6\u7f51\u819c\u8840\u7ba1\u75be\u75c5\u3002<\/p>\n

\u7ee7\u6b64\u6b21 IND \u7533\u8bf7\u83b7\u6279\uff0c\u853c\u7766\u533b\u7597\u5c06\u4f1a\u5c3d\u5feb\u5728\u7f8e\u56fd\u542f\u52a8\u4e00\u9879 1 \u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u7814\u7a76 AM712 (ASKG712) \u5728\u65b0\u751f\u8840\u7ba1\u6027 AMD \u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u7597\u6548\u3002<\/p>\n

\u853c\u7766\u533b\u7597\u5728\u524d\u4e0d\u4e45\u4e0e AskGene Pharma Inc.\uff08\u4ee5\u4e0b\u7b80\u79f0“AskGene”\uff09\u7b7e\u8ba2\u4e86\u4e00\u9879\u8bb8\u53ef\u534f\u8bae\uff0c\u83b7\u5f97\u4e86\u5728\u5168\u7403\u4e9a\u6d32\u4ee5\u5916\u5730\u533a\u548c\u65e5\u672c\u5e02\u573a\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u5546\u4e1a\u5316 AM712 (ASKG712) \u7684\u72ec\u5bb6\u6743\u5229\u3002<\/p>\n

\u853c\u7766\u533b\u7597\u9996\u5e2d\u6267\u884c\u5b98\u8d75\u5927\u5c27\u535a\u58eb\u8868\u793a\uff1a“\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0e AskGene \u5f00\u5c55\u5408\u4f5c\uff0c\u5e76\u6536\u83b7\u4e86\u6765\u81ea FDA\u7684\u9996\u4e2aIND\u6279\u51c6\u3002\u4f5c\u4e3a\u853c\u7766\u533b\u7597\u517c\u987e\u4e2d\u7f8e\u4e1a\u52a1\u5e03\u5c40\uff0c\u4e3a\u5168\u7403\u5e02\u573a\u63d0\u4f9b\u5dee\u5f02\u5316\u7597\u6cd5\u8fd9\u4e00\u56fd\u9645\u5316\u521b\u65b0\u6218\u7565\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\uff0c\u53cc\u65b9\u7684\u5408\u4f5c\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86\u6211\u4eec\u7684\u5168\u7403\u773c\u79d1\u4ea7\u54c1\u7ba1\u7ebf\u3002\u4ece\u7b7e\u7f72\u8bb8\u53ef\u534f\u8bae\u5230\u83b7\u5f97 FDA \u6279\u51c6\uff0c\u6211\u5f88\u9ad8\u5174\u89c1\u8bc1\u4e0a\u8ff0\u6218\u7565\u52a0\u901f\u843d\u5730\uff0c\u5e76\u671f\u5f85\u80fd\u591f\u4e0e AskGene \u5bc6\u5207\u5f00\u5c55\u540e\u7eed\u5408\u4f5c\u3002”<\/p>\n

AskGene \u9996\u5e2d\u6267\u884c\u5b98\u5362\u5efa\u4e30\u535a\u58eb\u8868\u793a\uff1a“AskGene \u81f4\u529b\u4e8e\u901a\u8fc7\u521b\u65b0\u6280\u672f\uff0c\u52a0\u5feb\u4e3a\u60a3\u8005\u63d0\u4f9b\u5b89\u5168\u548c\u6709\u6548\u7684\u836f\u7269\u3002\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u80fd\u591f\u4e0e\u853c\u7766\u533b\u7597\u5408\u4f5c\uff0c\u643a\u624b\u5f00\u53d1\u66f4\u5177\u6f5c\u529b\u7684\u6297 VEGF\/Ang-2\u53cc\u7279\u5f02\u6027\u5206\u5b50 AMG712 (ASKG712)\uff0c\u9020\u798f\u5168\u7403\u60a3\u8005\u3002\u853c\u7766\u533b\u7597\u56e2\u961f\u5728\u773c\u79d1\u9886\u57df\u7a81\u51fa\u7684\u5b9e\u529b\u548c\u4e30\u5bcc\u7684\u5168\u7403\u9879\u76ee\u7ecf\u9a8c\u662f\u4fc3\u6210\u5408\u4f5c\u7684\u91cd\u8981\u56e0\u7d20\u3002\u53cc\u65b9\u5c06\u7d27\u5bc6\u914d\u5408\uff0c\u5171\u540c\u52a0\u901f ASKG712 \u7684\u5168\u7403\u5f00\u53d1\u8fdb\u5ea6\u3002”<\/p>\n

\u853c\u7766\u533b\u7597\u603b\u88c1\u674e\u5b63\u535a\u58eb\u8868\u793a\uff1a“\u6211\u4eec\u76f8\u4fe1 AM712 (ASKG712) \u6709\u6f5c\u529b\u6210\u4e3a\u540c\u7c7b\u6700\u4f73\u6297 VEGF\/Ang-2 \u53cc\u7279\u5f02\u6027\u751f\u7269\u5206\u5b50\uff0c\u4ee5\u66f4\u597d\u89e3\u51b3\u89c6\u7f51\u819c\u75be\u75c5\u60a3\u8005\u5927\u91cf\u5c1a\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u5f88\u9ad8\u5174\u5728\u4e0e AskGene \u8fbe\u6210\u8bb8\u53ef\u4ea4\u6613\u540e\u77ed\u77ed 2 \u4e2a\u6708\u5185\u5c31\u83b7\u5f97\u7f8e\u56fd\u7684 IND \u6279\u51c6\uff0c\u8fd9\u5145\u5206\u5c55\u793a\u4e86\u6574\u4e2a\u56e2\u961f\u4f18\u5f02\u7684\u6267\u884c\u80fd\u529b\u3002”<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e0a\u6d772022\u5e742\u670815\u65e5 \/\u7f8e\u901a\u793e\/ — \u81f4\u529b\u4e8e\u6ee1\u8db3\u5168\u7403\u773c\u79d1\u3001\u795e\u7ecf\u548c\u7cbe\u795e\u7cfb\u7edf\u75be\u75c5\u6cbb\u7597\u9700\u6c42\u7684\u4e34\u5e8a\u9636\u6bb5\u521b\u65b0\u751f\u7269\u533b\u836f\u516c\u53f8\u853c\u7766\u533b\u7597\u4eca\u5929\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40 (\u4ee5\u4e0b\u7b80\u79f0“FDA”) \u5df2\u6279\u51c6\u5176 AM712 (ASKG712) \u7684\u4e34\u5e8a\u5f00\u53d1\u65b0\u836f\u7814\u7a76 (IND) \u7533\u8bf7\u3002AM712 \u662f\u4e00\u6b3e\u65b0\u578b\u53cc\u7279\u5f02\u6027\u751f\u7269\u5206\u5b50\uff0c\u80fd\u591f\u540c\u65f6\u963b\u65ad\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50 (VEGF) \u548c\u8840\u7ba1\u751f\u6210\u7d20-2 (Ang-2)\uff0c\u6cbb\u7597\u89c6\u7f51\u819c\u8840\u7ba1\u75be\u75c5\u3002 \u7ee7\u6b64\u6b21 IND \u7533\u8bf7\u83b7\u6279\uff0c\u853c\u7766\u533b\u7597\u5c06\u4f1a\u5c3d\u5feb\u5728\u7f8e\u56fd\u542f\u52a8\u4e00\u9879 1 \u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u7814\u7a76 AM712 (ASKG712) \u5728\u65b0\u751f\u8840\u7ba1\u6027 AMD \u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u7597\u6548\u3002 \u853c\u7766\u533b\u7597\u5728\u524d\u4e0d\u4e45\u4e0e AskGene Pharma Inc.\uff08\u4ee5\u4e0b\u7b80\u79f0“AskGene”\uff09\u7b7e\u8ba2\u4e86\u4e00\u9879\u8bb8\u53ef\u534f\u8bae\uff0c\u83b7\u5f97\u4e86\u5728\u5168\u7403\u4e9a\u6d32\u4ee5\u5916\u5730\u533a\u548c\u65e5\u672c\u5e02\u573a\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u5546\u4e1a\u5316 AM712 (ASKG712) \u7684\u72ec\u5bb6\u6743\u5229\u3002 \u853c\u7766\u533b\u7597\u9996\u5e2d\u6267\u884c\u5b98\u8d75\u5927\u5c27\u535a\u58eb\u8868\u793a\uff1a“\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0e AskGene \u5f00\u5c55\u5408\u4f5c\uff0c\u5e76\u6536\u83b7\u4e86\u6765\u81ea FDA\u7684\u9996\u4e2aIND\u6279\u51c6\u3002\u4f5c\u4e3a\u853c\u7766\u533b\u7597\u517c\u987e\u4e2d\u7f8e\u4e1a\u52a1\u5e03\u5c40\uff0c\u4e3a\u5168\u7403\u5e02\u573a\u63d0\u4f9b\u5dee\u5f02\u5316\u7597\u6cd5\u8fd9\u4e00\u56fd\u9645\u5316\u521b\u65b0\u6218\u7565\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\uff0c\u53cc\u65b9\u7684\u5408\u4f5c\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86\u6211\u4eec\u7684\u5168\u7403\u773c\u79d1\u4ea7\u54c1\u7ba1\u7ebf\u3002\u4ece\u7b7e\u7f72\u8bb8\u53ef\u534f\u8bae\u5230\u83b7\u5f97 FDA \u6279\u51c6\uff0c\u6211\u5f88\u9ad8\u5174\u89c1\u8bc1\u4e0a\u8ff0\u6218\u7565\u52a0\u901f\u843d\u5730\uff0c\u5e76\u671f\u5f85\u80fd\u591f\u4e0e AskGene \u5bc6\u5207\u5f00\u5c55\u540e\u7eed\u5408\u4f5c\u3002” AskGene \u9996\u5e2d\u6267\u884c\u5b98\u5362\u5efa\u4e30\u535a\u58eb\u8868\u793a\uff1a“AskGene \u81f4\u529b\u4e8e\u901a\u8fc7\u521b\u65b0\u6280\u672f\uff0c\u52a0\u5feb\u4e3a\u60a3\u8005\u63d0\u4f9b\u5b89\u5168\u548c\u6709\u6548\u7684\u836f\u7269\u3002\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u80fd\u591f\u4e0e\u853c\u7766\u533b\u7597\u5408\u4f5c\uff0c\u643a\u624b\u5f00\u53d1\u66f4\u5177\u6f5c\u529b\u7684\u6297 VEGF\/Ang-2\u53cc\u7279\u5f02\u6027\u5206\u5b50 AMG712 (ASKG712)\uff0c\u9020\u798f\u5168\u7403\u60a3\u8005\u3002\u853c\u7766\u533b\u7597\u56e2\u961f\u5728\u773c\u79d1\u9886\u57df\u7a81\u51fa\u7684\u5b9e\u529b\u548c\u4e30\u5bcc\u7684\u5168\u7403\u9879\u76ee\u7ecf\u9a8c\u662f\u4fc3\u6210\u5408\u4f5c\u7684\u91cd\u8981\u56e0\u7d20\u3002\u53cc\u65b9\u5c06\u7d27\u5bc6\u914d\u5408\uff0c\u5171\u540c\u52a0\u901f ASKG712 \u7684\u5168\u7403\u5f00\u53d1\u8fdb\u5ea6\u3002” \u853c\u7766\u533b\u7597\u603b\u88c1\u674e\u5b63\u535a\u58eb\u8868\u793a\uff1a“\u6211\u4eec\u76f8\u4fe1 AM712 (ASKG712) \u6709\u6f5c\u529b\u6210\u4e3a\u540c\u7c7b\u6700\u4f73\u6297 VEGF\/Ang-2 \u53cc\u7279\u5f02\u6027\u751f\u7269\u5206\u5b50\uff0c\u4ee5\u66f4\u597d\u89e3\u51b3\u89c6\u7f51\u819c\u75be\u75c5\u60a3\u8005\u5927\u91cf\u5c1a\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u5f88\u9ad8\u5174\u5728\u4e0e AskGene \u8fbe\u6210\u8bb8\u53ef\u4ea4\u6613\u540e\u77ed\u77ed 2 \u4e2a\u6708\u5185\u5c31\u83b7\u5f97\u7f8e\u56fd\u7684 IND \u6279\u51c6\uff0c\u8fd9\u5145\u5206\u5c55\u793a\u4e86\u6574\u4e2a\u56e2\u961f\u4f18\u5f02\u7684\u6267\u884c\u80fd\u529b\u3002”… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":8278,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-62362","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/62362","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=62362"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/62362\/revisions"}],"predecessor-version":[{"id":62363,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/62362\/revisions\/62363"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/8278"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=62362"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=62362"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=62362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}