{"id":61493,"date":"2022-01-26T17:00:00","date_gmt":"2022-01-26T10:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2022012617000061493"},"modified":"2022-01-27T18:02:23","modified_gmt":"2022-01-27T10:02:23","slug":"trailr2-cdh17%e5%8f%8c%e7%89%b9%e5%bc%82%e6%80%a7%e6%8a%97%e4%bd%93bi-905711-%e2%85%b0%e6%9c%9f%e4%b8%b4%e5%ba%8a%e7%a0%94%e7%a9%b6%e9%a6%96%e4%b8%aa%e6%82%a3%e8%80%85%e5%85%a5%e7%bb%84","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2022012617000061493","title":{"rendered":"TRAILR2\/CDH17\u53cc\u7279\u5f02\u6027\u6297\u4f53BI 905711 — \u2160\u671f\u4e34\u5e8a\u7814\u7a76\u9996\u4e2a\u60a3\u8005\u5165\u7ec4"},"content":{"rendered":"

\u4e0a\u6d772022\u5e741\u670826\u65e5 \/\u7f8e\u901a\u793e\/ — \u52c3\u6797\u683c\u6bb7\u683c\u7ff0\u4e0e\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u5408\u4f5c\u7684BI 905711\u8054\u5408\u5316\u7597\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u9879\u76ee\u843d\u5730\u56fd\u5185\uff0c\u6210\u529f\u5165\u7ec4\u5168\u7403\u9996\u4f8b\u60a3\u8005\u3002<\/p>\n

2022\u5e741\u6708\uff0c\u7531\u4e2d\u56fd\u6d88\u5316\u80bf\u7624\u4e13\u5bb6\u6c88\u7433\u6559\u6388\u7275\u5934\u5f00\u5c55\u665a\u671f\u80c3\u80a0\u9053\u764c\u75c7\u521b\u65b0\u836f\u7269\uff08\u4fc3\u51cb\u4ea1\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\uff08TNF\uff09\u76f8\u5173\u51cb\u4ea1\u8bf1\u5bfc\u914d\u4f53\u53d7\u4f532\uff08TRAILR2\uff09\/\u80bf\u7624\u7ec6\u80de\u951a\u5b9a\u9499\u7c98\u86cb\u767d17\uff08CDH17\uff09\u53cc\u7279\u5f02\u6027\u6297\u4f53BI 905711\uff09\u76f8\u5173\u4e34\u5e8a\u7814\u7a76\uff0c\u6210\u529f\u5165\u7ec4\u5168\u7403\u9996\u4f8b\u665a\u671f\u80c3\u80a0\u9053\u764c\u60a3\u8005<\/b>\u3002BI 905711\u901a\u8fc7\u6fc0\u6d3b\u5171\u540c\u8868\u8fbeTRAILR2\u548cCDH17\u7684\u80bf\u7624\u7ec6\u80de\u4e2d\u7684\u51cb\u4ea1\u901a\u8def\uff0c\u4ece\u800c\u904f\u5236\u80bf\u7624\u8fdb\u5c55\u3002\u5176\u7ed3\u5408\u4e86\u80bf\u7624\u9776\u5411\u6cbb\u7597\u548c\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\uff0c\u4e3a\u665a\u671f\u6d88\u5316\u9053\u6076\u6027\u80bf\u7624\u60a3\u8005\u5e26\u6765\u4e86\u65b0\u5e0c\u671b\u3002<\/p>\n

\u80c3\u80a0\u9053\u6076\u6027\u80bf\u7624\u6cbb\u7597 — \u4e9f\u5f85\u5168\u65b0\u6cbb\u7597\u7b56\u7565\u7834\u5c40<\/b><\/p>\n

\u8fd1\u5e74\u6765\uff0c\u5168\u7403\u80c3\u80a0\u9053\u6076\u6027\u80bf\u7624\u7684\u53d1\u75c5\u7387\u53ca\u6b7b\u4ea1\u7387\u5747\u5448\u73b0\u9010\u5e74\u4e0a\u5347\u8d8b\u52bf\uff0c\u5176\u5df2\u6210\u4e3a\u5168\u7403\u6076\u6027\u80bf\u7624\u76f8\u5173\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u3002\u4ee5\u7ed3\u76f4\u80a0\u764c\uff08CRC\uff09\u4e3a\u4f8b\uff0c\u6700\u65b0\u7edf\u8ba1\u6570\u636e\u8868\u660e\uff0c2020\u5e74\uff0c\u5168\u7403CRC\u53d1\u75c5\u7387\u53ca\u6b7b\u4ea1\u7387\u5747\u5c45\u6240\u6709\u6076\u6027\u80bf\u7624\u524d\u4e94\u4f4d[1]<\/sup>\uff0c\u4e0e\u6b64\u540c\u65f6\uff0c\u7ea6\u670930%\u7684\u60a3\u8005\u5728\u786e\u8bca\u65f6\u5373\u5df2\u53d1\u751f\u8f6c\u79fb\u6216\u5df2\u8fdb\u5c55\u81f3\u665a\u671f\uff0c\u4e27\u5931\u624b\u672f\u673a\u4f1a\u3002\u957f\u671f\u4ee5\u6765\uff0c\u665a\u671f\u6d88\u5316\u9053\u6076\u6027\u80bf\u7624\u7684\u6cbb\u7597\uff0c\u90fd\u662f\u4ee5\u5316\u7597\u4e3a\u57fa\u7840\u7684\u5355\u836f\u6216\u8054\u5408\u6cbb\u7597\u65b9\u6848\uff0c\u867d\u7136\u5316\u7597\u836f\u7269\u53ca\u8054\u5408\u6cbb\u7597\u7b56\u7565\u8fed\u4ee3\u66f4\u65b0\uff0c\u4f46\u7597\u6548\u59cb\u7ec8\u672a\u80fd\u83b7\u5f97\u7a81\u7834\u6027\u8fdb\u5c55\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u7ec6\u80de\u6bd2\u6027\u836f\u7269\u5e26\u6765\u7684\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\uff0c\u6210\u4e3a\u665a\u671f\u6d88\u5316\u6076\u6027\u80bf\u7624\u60a3\u8005\u63a5\u53d7\u6cbb\u7597\u7684\u4e00\u5927\u969c\u788d\u3002<\/p>\n

\u8fd1\u5e74\u6765\uff0c\u968f\u7740\u6076\u6027\u80bf\u7624\u6cbb\u7597\u8fdb\u5165\u9776\u5411\u3001\u514d\u75ab\u6cbb\u7597\u65f6\u4ee3\u3002\u65b0\u578b\u9776\u5411\u6cbb\u7597\u836f\u7269\u4e0d\u65ad\u6d8c\u73b0\uff0c\u76ee\u524d\u5df2\u5728\u591a\u79cd\u6076\u6027\u80bf\u7624\u6cbb\u7597\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u5728\u5f88\u591a\u7624\u79cd\u7684\u6cbb\u7597\u4e2d\u4eba\u7c7b\u9010\u6e10\u6446\u8131\u201c\u552f\u5316\u7597\u8bba\u201d\u7684\u6cbb\u7597\u56f0\u5883\uff0c\u8fce\u6765\u4e86\u9664\u7ec6\u80de\u6bd2\u836f\u7269\u5916\u66f4\u4e3a\u591a\u6837\u5316\u7684\u6cbb\u7597\u9009\u62e9\u3002\u665a\u671f\u6d88\u5316\u9053\u6076\u6027\u80bf\u7624\u60a3\u8005\u540c\u6837\u4e9f\u5f85\u5168\u65b0\u9ad8\u6548\u3001\u5b89\u5168\u3001\u4f4e\u6bd2\u7684\u6cbb\u7597\u836f\u7269\u6539\u53d8\u76ee\u524d\u56f0\u5883\u3002<\/p>\n

TRAILR2\/CDH17\u53cc\u7279\u5f02\u6027\u6297\u4f53BI 905711 — <\/b>\u665a\u671f\u80c3\u80a0\u9053\u80bf\u7624\u60a3\u8005\u65b0\u5e0c\u671b<\/b><\/p>\n

BI 905711\u4f5c\u4e3a\u4e00\u79cd\u9996\u521b\u7684\u53cc\u7279\u5f02\u6027\u3001\u56db\u4ef7\u6297\u4f53\uff0c\u5176\u80fd\u591f\u540c\u65f6\u8bc6\u522b\u4fc3\u51cb\u4ea1\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\uff08TNF\uff09\u76f8\u5173\u51cb\u4ea1\u8bf1\u5bfc\u914d\u4f53\u53d7\u4f532\uff08TRAILR2\uff09\u548c\u80bf\u7624\u7ec6\u80de\u951a\u5b9a\u9499\u7c98\u86cb\u767d17\uff08CDH17\uff09\u3002<\/p>\n

TRAILR2\u662fTNF\u53d7\u4f53\u8d85\u5bb6\u65cf\u7684\u6210\u5458\uff0c\u4f5c\u4e3a\u662f\u4e00\u79cd\u4fc3\u51cb\u4ea1\u53d7\u4f53\uff0c\u5728\u6076\u6027\u80bf\u7624\u4e2d\u5e7f\u6cdb\u8868\u8fbe\u3002\u5176\u80fd\u6709\u6548\u5730\u8bf1\u5bfc\u591a\u79cd\u80bf\u7624\u7ec6\u80de\u7cfb\u51cb\u4ea1\uff0c\u4f46\u4e0d\u4f1a\u8bf1\u5bfc\u5927\u591a\u6570\u6b63\u5e38\u7ec6\u80de\u51cb\u4ea1\u3002\u4e0d\u4ec5\u5982\u6b64\uff0cTRAILR2\u8fd8\u53ef\u4ee5\u901a\u8fc7\u4e0e\u914d\u4f53\u5f15\u53d1\u7684\u4f4e\u805a\u53cd\u5e94\u76f4\u63a5\u542f\u52a8\u5916\u6e90\u6027\u51cb\u4ea1\u9014\u5f84\uff0c\u5e76\u5177\u6709\u4e0e\u5176\u5b83\u51cb\u4ea1\u8c03\u63a7\u56e0\u5b50\u7ed3\u5408\u7684\u6f5c\u80fd\u3002<\/p>\n<\/p>\n

\n

\"\u56fe1<\/a>
\u56fe1 TRAILR2\u8bf1\u5bfc\u7ec6\u80de\u51cb\u4ea1\u673a\u5236<\/span><\/p>\n<\/p><\/div>\n

\u800cCDH17\u4f5c\u4e3a\u9499\u9ecf\u86cb\u767d\u8d85\u5bb6\u65cf\u6210\u5458\u4e4b\u4e00\uff0c\u5177\u6709\u7279\u6b8a\u7684\u7ed3\u6784\u7279\u5f81\u3002\u5176\u4e3b\u8981\u8868\u8fbe\u4e8e\u80a0\u4e0a\u76ae\u7ec6\u80de\u53ca\u90e8\u5206\u80f0\u817a\u5bfc\u7ba1\u4e0a\u76ae\u7ec6\u80de<\/a>\uff0c\u5728\u7ec6\u80de\u751f\u957f\u53d1\u80b2\u8fc7\u7a0b\u4e2d\u8d77\u5230\u91cd\u8981\u4f5c\u7528\u3002CDH17\u7ed3\u6784\u5f02\u5e38\u548c\u529f\u80fd\u7d0a\u4e71\u4f1a\u5bfc\u81f4\u80bf\u7624\u7ec6\u80de\u95f4\u7c98\u9644\u80fd\u529b\u4e0b\u964d\u3002\u7ec4\u7ec7\u7ec6\u80de\u677e\u6563\uff0c\u6613\u4e8e\u8131\u843d\u6216\u53d8\u5f62\uff0c\u4ece\u800c\u4f7f\u7624\u7ec6\u80de\u83b7\u5f97\u66f4\u5f3a\u7684\u4fb5\u88ad\u529b\uff0c\u4fc3\u8fdb\u80bf\u7624\u7684\u4fb5\u88ad\u4e0e\u8f6c\u79fb\u3002<\/p>\n

BI 905711\u7684\u4f5c\u7528\u673a\u5236\u6b63\u662f\u4f9d\u6258\u4e0a\u8ff0\u5728\u80bf\u7624\u7ec6\u80de\u4e2d\u9ad8\u8868\u8fbe\u7684\u7279\u6b8a\u7ed3\u6784\uff0c\u8bc6\u522b\u5728\u80c3\u80a0\u9053\u4e2d\u5b58\u5728TRAILR2\/CDH17\u5171\u8868\u8fbe\u7684\u80bf\u7624\u7ec6\u80de\uff0c\u5e76\u6fc0\u6d3b\u5176\u51cb\u4ea1\u901a\u8def\u3002\u4ece\u800c\u8fbe\u5230\u63a7\u5236\u80bf\u7624\u8fdb\u5c55\uff0c\u4fc3\u8fdb\u80bf\u7624\u7ec6\u80de\u51cb\u4ea1\u7684\u76ee\u7684\u3002<\/p>\n<\/p>\n

\n

\"\u56fe2<\/a>
\u56fe2 \u80bf\u7624\u7ec6\u80de\u4e2dTRAILR2\/CDH17\u4f5c\u7528\u673a\u5236<\/span><\/p>\n<\/p><\/div>\n

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\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

[1]<\/sup> World Health Organization. International Agency for Research on Cancer. 7-Stomach-fact-sheet. Available at https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/7-Stomach-fact-sheet.pdf<\/span><\/a> <\/span><\/p>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

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\u53c2\u8003\u6587\u732e\uff1a [1] World Health Organization. International Agency for Research on Cancer. 7-Stomach-fact-sheet. Available at https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/7-Stomach-fact-sheet.pdf … Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":61497,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-61493","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/61493","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=61493"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/61493\/revisions"}],"predecessor-version":[{"id":61496,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/61493\/revisions\/61496"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/61497"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=61493"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=61493"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=61493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}