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\u5fae\u7403\u5236\u5242\u66f4\u9002\u4e8e\u6208\u820d\u745e\u6797\u53d1\u6325\u6cbb\u7597\u4f5c\u7528\uff0c\u4e14\u5b89\u5168\u4f18\u52bf\u663e\u8457<\/b><\/p>\n

\u4f5c\u4e3a\u524d\u5217\u817a\u764c\u91cd\u8981\u7684\u5168\u8eab\u6cbb\u7597\u624b\u6bb5\uff0c\u96c4\u6fc0\u7d20\u5265\u593a\u6cbb\u7597\uff08Androgen Deprivation Therapy\uff0cADT\uff09\u5728\u8be5\u75be\u75c5\u4e0d\u540c\u5206\u671f\u7684\u6cbb\u7597\u73af\u8282\u4e2d\u5747\u53d1\u6325\u7740\u201c\u57fa\u77f3\u201d\u4f5c\u7528\u3002\u800c\u4ee5\u6208\u820d\u745e\u6797\u4e3a\u4ee3\u8868\u7684\u4fc3\u6027\u817a\u6fc0\u7d20\u91ca\u653e\u6fc0\u7d20\uff08Gonadotropin-releasing hormone, GnRH\uff09\u6fc0\u52a8\u5242\u662fADT\u6cbb\u7597\u6700\u5e38\u89c1\u7684\u4e00\u7c7b\u836f\u7269\uff0c\u53ef\u6709\u6548\u63a7\u5236\u777e\u916e\u81f3\u53bb\u52bf\u6c34\u5e73\uff0c\u5ef6\u7f13\u75be\u75c5\u53d1\u5c55\uff0c\u63d0\u9ad8\u60a3\u8005\u751f\u5b58\u83b7\u76ca\u3002<\/p>\n

\u7136\u800c\uff0c\u6208\u820d\u745e\u6797\u7b49GnRH\u6fc0\u52a8\u5242\u5728\u4e34\u5e8a\u4e0a\u9700\u8981\u4ee5\u7f13\u91ca\u7684\u65b9\u5f0f\u6765\u8fbe\u5230\u6301\u7eed\u7684\u836f\u7269\u91ca\u653e\uff0c\u8fdb\u800c\u4ea7\u751f\u6cbb\u7597\u4f5c\u7528\u3002\u4f5c\u4e3a\u524d\u5217\u817a\u764c\u6cbb\u7597\u7684\u4e00\u7ebf\u836f\u7269\uff0c\u76ee\u524d\u6208\u820d\u745e\u6797\u5df2\u4e0a\u5e02\u7684\u552f\u4e00\u5242\u578b\u4e3a\u76ae\u4e0b\u690d\u5165\u5242\u3002<\/p>\n

LY01005\u901a\u8fc7\u521b\u65b0\u5fae\u7403\u6280\u672f\uff0c\u901a\u8fc7\u808c\u8089\u6ce8\u5c04\u7684\u65b9\u5f0f\u4ee5\u6bcf\u6708\u4e00\u6b21\u7684\u9891\u7387\u7ed9\u836f\uff0c\u5728\u7ed9\u836f\u5468\u671f\u5185\u53ef\u5b9e\u73b0\u5e73\u7a33\u7684\u836f\u7269\u91ca\u653e\u3002LY01005\u53ef\u51cf\u5c11\u6ce8\u5c04\u90e8\u4f4d\u4e0d\u826f\u53cd\u5e94\uff0c\u63d0\u9ad8\u60a3\u8005\u7528\u836f\u611f\u53d7\uff0c\u51cf\u8f7b\u62a4\u7406\u96be\u5ea6\uff0c\u63d0\u5347\u60a3\u8005\u7684\u8010\u53d7\u6027\u548c\u4f9d\u4ece\u6027\uff0c\u66f4\u5229\u4e8e\u836f\u7269\u53d1\u6325\u6cbb\u7597\u4f5c\u7528\uff0c\u5177\u6709\u660e\u663e\u7684\u4e34\u5e8a\u4f18\u52bf\u3002<\/p>\n

LY01005<\/b>\u6709\u671b\u6210\u4e3a\u5168\u7403\u552f\u4e00\u6208\u820d\u745e\u6797\u5fae\u7403\u5236\u5242<\/b><\/p>\n

\u524d\u5217\u817a\u764c\u662f\u7537\u6027\u7b2c\u4e8c\u5927\u5e38\u89c1\u764c\u75c7\u548c\u7b2c\u4e94\u5927\u764c\u75c7\u6b7b\u4ea1\u539f\u56e0\uff0c\u4e3a\u5168\u7403\u8d85\u8fc7\u4e00\u534a\u7684\u56fd\u5bb6\u7537\u6027\u4e2d\u6700\u5e38\u8bca\u65ad\u7684\u764c\u75c7[1]<\/sup>\u30022020\u5e74\uff0c\u524d\u5217\u817a\u764c\u5728\u5168\u7403\u7684\u65b0\u53d1\u75c5\u4f8b\u7ea6\u4e3a141\u4e07\u4f8b\uff0c\u6b7b\u4ea1\u4eba\u6570\u7ea6\u8fbe37.5\u4e07\u4f8b\uff1b\u5728\u4e2d\u56fd\uff0c\u524d\u5217\u817a\u764c\u7684\u65b0\u53d1\u75c5\u4f8b\u8d85\u8fc711.5\u4e07\u4f8b\uff0c\u6b7b\u4ea1\u4eba\u6570\u8d85\u8fc75\u4e07\u4eba[2]<\/sup>\u3002\u57fa\u4e8e\u5927\u91cf\u7684\u60a3\u8005\u9700\u6c42\uff0c2020\u5e74\u4e2d\u56fdGnRH\u6fc0\u52a8\u5242\u4ea7\u54c1\u7684\u5e02\u573a\u603b\u503c\u7ea6\u8fbe\u5230\u4eba\u6c11\u5e0174.5\u4ebf\u5143\uff0c2018\u5e74\u81f32020\u5e74\u7684\u590d\u5408\u5e74\u5747\u589e\u957f\u7387\u8fbe\u523022.6%[3]<\/sup>\u3002<\/p>\n

LY01005\u6709\u671b\u6210\u4e3a\u5168\u7403\u552f\u4e00\u7684\u6208\u820d\u745e\u6797\u5fae\u7403\u5236\u5242\uff0c\u4e3a\u5e7f\u5927\u60a3\u8005\u5e26\u6765\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002\u9664\u4e86\u524d\u5217\u817a\u764c\uff0cLY01005\u6cbb\u7597\u4e73\u817a\u764c\u7684\u4e2d\u56fdIII\u671f\u4e34\u5e8a\u7814\u7a76\u4e5f\u5728\u987a\u5229\u8fdb\u884c\u4e2d\u3002<\/p>\n

\u5168\u7403\u9886\u5148\u5fae\u7403\u6280\u672f\u5e73\u53f0\u521b\u65b0\u6210\u679c\u52a0\u901f\u8f6c\u5316<\/b><\/p>\n

\u5fae\u7403\u5236\u5242\u4f5c\u4e3a\u65b0\u578b\u9ad8\u7aef\u5236\u5242\uff0c\u53ef\u9488\u5bf9\u4e34\u5e8a\u9700\u6c42\u8bbe\u8ba1\u4e0d\u540c\u7684\u91ca\u653e\u901f\u5ea6\u548c\u5468\u671f\uff0c\u5b9e\u73b0\u5e73\u7a33\u6301\u7eed\u91ca\u653e\u836f\u7269\u4e00\u5468\u81f3\u6570\u6708\uff0c\u8fdb\u800c\u63d0\u9ad8\u7597\u6548\uff0c\u63d0\u5347\u6cbb\u7597\u5b89\u5168\u6027\u548c\u4f9d\u4ece\u6027\uff0c\u5177\u6709\u660e\u663e\u7684\u4e34\u5e8a\u4f18\u52bf\u3002<\/p>\n

\u7136\u800c\uff0c\u4f5c\u4e3a\u4e00\u79cd\u590d\u6742\u5236\u5242\uff0c\u5fae\u7403\u5236\u5242\u7684\u7814\u53d1\u3001\u751f\u4ea7\u96be\u5ea6\u5927\u3001\u6280\u672f\u58c1\u5792\u9ad8\uff0c\u8be5\u6280\u672f\u4e3b\u8981\u88ab\u51e0\u5bb6\u56fd\u5916\u4f01\u4e1a\u6240\u638c\u63e1\u3002\u7eff\u53f6\u5236\u836f\u5728\u521b\u65b0\u5fae\u7403\u6280\u672f\u7814\u53d1\u9886\u57df\u6df1\u8015\u591a\u5e74\uff0c\u5df2\u6210\u529f\u5b9e\u73b0\u4ea7\u4e1a\u5316\u8f6c\u6362\uff0c\u65e0\u8bba\u662fLY01005\u8fd8\u662f\u5df2\u4e0a\u5e02\u7684\u745e\u6b23\u59a5®<\/sup>\uff0c\u5728\u6253\u7834\u6280\u672f\u5784\u65ad\u7684\u540c\u65f6\uff0c\u5c06\u964d\u4f4e\u60a3\u8005\u533b\u7597\u8d39\u7528\uff0c\u63d0\u5347\u836f\u7269\u53ef\u53ca\u6027\u3002<\/p>\n

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[1] Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021 Feb 4<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[2] \u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u56fd\u9645\u764c\u75c7\u7814\u7a76\u673a\u6784\uff08IARC\uff092020\u5e74\u5168\u7403\u6700\u65b0\u764c\u75c7\u8d1f\u62c5\u6570\u636e<\/span><\/p>\n<\/td>\n<\/tr>\n

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[3] IQVIA\u6570\u636e<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n","protected":false},"excerpt":{"rendered":"

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Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. 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