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BC-PIV\u662fBioComo\u548c\u4e09\u91cd\u5927\u5b66\u8054\u5408\u5f00\u53d1\u7684\u4e00\u79cd\u521b\u65b0\u578b\u975e\u4f20\u67d3\u6027\u75c5\u6bd2\u8f7d\u4f53\uff0c\u6e90\u81ea\u91cd\u7ec4\u4eba\u526f\u6d41\u611f2\u578b\u75c5\u6bd2(hPIV2)\u3002BC-PIV\u662f\u4e00\u79cd\u9488\u5bf9SARS-CoV-2\u7684\u9f3b\u5185\u75ab\u82d7\uff0c\u901a\u8fc7\u8bf1\u5bfc\u9ad8\u6c34\u5e73\u4e2d\u548c\u514d\u75ab\u7403\u86cb\u767dG\u548c\u7c98\u819c\u514d\u75ab\u7403\u86cb\u767dA\u6297\u4f53\u6765\u5bf9\u6297\u523a\u7a81\u86cb\u767d\uff0c\u5b8c\u5168\u4fdd\u62a4\u4e86\u4ed3\u9f20\u7684\u80ba\u90e8\u548c\u51e0\u4e4e\u6574\u4e2a\u9f3b\u7532\u9aa8\u514d\u53d7SARS-CoV-2\u7684\u611f\u67d3\u3002\u9f3b\u5185BC-PIV\u75ab\u82d7\u6709\u671b\u6210\u4e3a\u5bf9\u6297SARS-CoV-2\u611f\u67d3\/\u4f20\u64ad\u7684\u5019\u9009\u75ab\u82d7\u3002<\/p>\n

\u4e09\u91cd\u5927\u5b66\u548cBioComo\u4e8e2021\u5e7411\u670817\u65e5\u5728\u7f8e\u56fd\u79d1\u5b66\u671f\u520a\u300a<\/b>iScience\u300b<\/b>\u4e0a\u53d1\u8868\u4e86\u8fd9\u4e00\u6700\u65b0\u53d1\u73b0\u3002\u52a8\u7269\u8bd5\u9a8c\u663e\u793a\u51fa\u4ee4\u4eba\u5174\u594b\u7684\u7ed3\u679c\uff0c\u8fd9\u8868\u660e\u53ef\u80fd\u4f1a\u7814\u53d1\u51fa\u6709\u6548\u7684\u51a0\u72b6\u75c5\u6bd2\u9f3b\u5185\u75ab\u82d7\uff0c\u4ee5\u5bf9\u6297SARS-CoV-2\u7684\u611f\u67d3\/\u4f20\u64ad\uff0c\u5b83\u4e0e\u73b0\u5df2\u83b7\u5f97\u6279\u51c6\u7684\u75ab\u82d7\u5b58\u5728\u5f88\u5927\u7684\u4e0d\u540c\u3002BC-PIV\u53ef\u88ab\u7528\u4f5c\u52a0\u5f3a\u63a5\u79cd\uff0c\u89e3\u51b3\u5e02\u9762\u4e0a\u75ab\u82d7\u514d\u75ab\u529b\u51cf\u5f31\u7684\u95ee\u9898[1]<\/sup>\u3002\u7814\u7a76\u4e2d\u8fdb\u884c\u7684\u6291\u5236\u8bd5\u9a8c\u901a\u8fc7\u91c7\u7528\u6765\u81eaSARS-CoV-2\u66ff\u4ee3\u4e2d\u548c\uff08cPass™\u8bd5\u5242\u76d2\uff09\u68c0\u6d4b\uff08\u91d1\u65af\u745e\uff09\u7684ELISA\u65b9\u6cd5\u7814\u7a76\u4e86SARS-CoV-2 RBD\u548chACE2\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528[1]<\/sup>\u3002\u76ee\u524d\uff0c\u5168\u7403\u5bf9\u9f3b\u55b7\u96fe\u75ab\u82d7\u4f5c\u4e3a\u201c\u4e0b\u4e00\u4ee3\u75ab\u82d7\u201d\u7684\u7ade\u4e89\u975e\u5e38\u6fc0\u70c8\u3002\u5728\u4e0d\u4e45\u7684\u5c06\u6765\uff0c\u4e09\u91cd\u5927\u5b66\u548cBioComo\u5c06\u8fdb\u5165\u4e0b\u4e00\u9636\u6bb5\u7684\u8c03\u7814\uff0c\u4ee5\u786e\u4fdd\u8d28\u91cf\u548c\u5b89\u5168\u6027\uff0c\u4e4b\u540e\u4e00\u5e74\u5185\u5c06\u8fdb\u884cI\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\u4e2d\u548c\u6297\u4f53\u662f\u786e\u5b9a\u75ab\u82d7\u529f\u6548\u7684\u4e00\u4e2a\u5173\u952e\u751f\u7269\u6807\u5fd7\u7269\u3002cPass™ sVNT\u8bd5\u5242\u76d2\u80fd\u591f\u68c0\u6d4b\u4e2a\u4f53\u63a5\u79cd\u75ab\u82d7\u540e\u548c\u611f\u67d3\u65b0\u51a0\u75c5\u6bd2\u540e\u7684\u529f\u80fd\u6027\u4e2d\u548c\u6297\u4f53\uff0c\u7701\u53bb\u4e86\u4f20\u7edf\u7684\u590d\u6742\u4e14\u8017\u65f6\u8d39\u529b\u7684\u5b9e\u9a8c\u5ba4\u7a0b\u5e8f\u3002\u8be5\u8bd5\u5242\u76d2\u53ef\u5728\u5927\u591a\u6570\u6807\u51c6\u5b9e\u9a8c\u5ba4\u4e2d\u8fdb\u884c\uff0c\u5468\u8f6c\u65f6\u95f4\u5f88\u77ed\uff08\u7ea61\u5c0f\u65f6\uff09\u3002\u5b83\u8fd8\u9002\u7528\u4e8e\u9ad8\u541e\u5410\u91cf\u548c\u5168\u81ea\u52a8\u6d4b\u8bd5\u3002cPass™ sVNT\u8bd5\u5242\u76d2\u4e5f\u56e0\u6b64\u6210\u4e3a\u9ad8\u901a\u91cf\u73af\u5883\u4e0b\u8bc4\u4f30\u75ab\u82d7\u529f\u6548\u7684\u7406\u60f3\u5de5\u5177\u3002\u91d1\u65af\u745e\u7684cPass™ sVNT\u8bd5\u5242\u76d2\u662f\u9996\u4e2a\u5546\u7528SARS-CoV-2\u4e2d\u548c\u6297\u4f53\u68c0\u6d4b\u8bd5\u5242\u76d2\uff0c\u5df2\u5206\u522b\u83b7\u5f97\u65b0\u52a0\u5761\u536b\u751f\u79d1\u5b66\u5c40(HSA)\u7684\u4e34\u65f6\u6388\u6743\u3001\u6b27\u6d32\u7684CE-IVD\u8ba4\u8bc1\u548c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40(FDA)\u7684\u7d27\u6025\u4f7f\u7528\u6388\u6743(EUA)\u3002<\/p>\n

BioComo, Inc.\u603b\u88c1Masayuki Fukumura\u8bc4\u8bba\u8bf4\uff1a\u201c\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u6709\u673a\u4f1a\u4e0e\u91d1\u65af\u745e\u5408\u4f5c\uff0c\u4e00\u8d77\u52a0\u5febSARS-CoV-2\u75ab\u82d7\u7684\u5f00\u53d1\u3002\u6211\u4eec\u7684\u4f7f\u547d\u662f\u5b75\u5316\u4e0b\u4e00\u4ee3\u6cbb\u7597\u6216\u9884\u9632\u611f\u67d3\u7684\u75ab\u82d7\u6280\u672f\u548c\u4ea7\u54c1\uff0c\u63a8\u52a8\u521b\u65b0\uff0c\u8ba9\u5927\u5bb6\u6d3b\u5f97\u66f4\u4e45\u3001\u66f4\u5065\u5eb7\u3002\u6211\u4eec\u5c06\u4e0e\u91d1\u65af\u745e\u4e00\u8d77\u52aa\u529b\u5f00\u53d1\u65b0\u578b\u9f3b\u5185SARS-CoV-2\u51a0\u72b6\u75c5\u6bd2\u75ab\u82d7\uff0c\u5e76\u5c3d\u4e00\u5207\u52aa\u529b\u5c06\u8fd9\u79cd\u75ab\u82d7\u5c3d\u5feb\u63d0\u4f9b\u7ed9\u6bcf\u4e2a\u4eba\u3002\u201d<\/p>\n

\u91d1\u65af\u745e\u4e9a\u592a\u533a\u603b\u88c1Johnson Wang\u8868\u793a\uff1a\u201c\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0eBioComo\u5408\u4f5c\uff0c\u4e00\u8d77\u52a0\u5febSARS-CoV-2\u75ab\u82d7\u7684\u5f00\u53d1\u3002\u91d1\u65af\u745e\u81f4\u529b\u4e8e\u63d0\u4f9b\u4e0d\u540c\u7684\u5c16\u7aef\u4ea7\u54c1\uff0c\u5e76\u5c06\u4e13\u6709\u6280\u672f\u5e94\u7528\u5230\u5404\u4e2a\u9886\u57df\uff0c\u4ee5\u52a0\u5feb\u5168\u7403\u7814\u53d1\u5de5\u4f5c\u3002\u51ed\u501fBioComo\u5728\u75ab\u82d7\u5f00\u53d1\u548c\u4e34\u5e8a\u7814\u7a76\u65b9\u9762\u7684\u4e30\u5bcc\u7ecf\u9a8c\u548c\u516c\u8ba4\u7684\u826f\u597d\u8bb0\u5f55\uff0c\u8fd9\u6b21\u5408\u4f5c\u5c06\u4f7f\u6211\u4eec\u80fd\u591f\u4e0e\u5ba2\u6237\u7684\u4e16\u754c\u4e00\u6d41\u4e13\u5bb6\u5408\u4f5c\uff0c\u63a8\u8fdb\u6211\u4eec\u5728\u751f\u547d\u79d1\u5b66\u7814\u7a76\u65b9\u9762\u7684\u7efc\u5408\u670d\u52a1\u3002\u6211\u4eec\u5e0c\u671bBC-PIV SARS-CoV-2\u75ab\u82d7\u80fd\u591f\u5927\u83b7\u6210\u529f\uff0c\u5c3d\u5feb\u9020\u798f\u516c\u4f17\u3002\u201d<\/p>\n

\u53c2\u8003\uff1a<\/b><\/p>\n

1. Ohtsuka<\/i> et al., Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2,iScience <\/i><\/b>(2021) https:\/\/doi.org\/10.1016\/j.isci.2021.103379<\/a><\/i><\/p>\n

\u5173\u4e8e<\/b>BioComo<\/b><\/p>\n

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\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1awww.biocomo.jp<\/a><\/p>\n

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