–<\/i>\u88ab\u5217\u5165<\/i>\u201c<\/i>\u5927\u4f1a\u6700\u4f73\u6458\u8981<\/i>\u201d<\/i>\u662f\u4e00\u9879\u6b8a\u8363\uff0c\u8868\u660e<\/i> AASLD <\/i>\u8bc4\u8bae\u59d4\u5458\u4f1a\u5bf9\u6b4c\u793c\u5728\u6162\u6027\u4e59\u578b\u809d\u708e\u9886\u57df\u7684\u7814\u7a76\u7ed9\u4e88\u4e86\u9ad8\u5ea6\u8bc4\u4ef7<\/i><\/p>\n
-IIb<\/i>\u671f\u7814\u7a76\u663e\u793a\uff0c\u5728\u57fa\u7ebf\u4e59\u809d\u8868\u9762\u6297\u539f<\/i>\u2264 500 IU\/mL<\/i>\u7684\u60a3\u8005\u4e2d\uff0c\u6cbb\u7597\u7ec4<\/i>19%<\/i>\u7684\u60a3\u8005\u4e59\u809d\u8868\u9762\u6297\u539f\u6301\u7eed\u6d88\u5931\uff0c\u800c\u5b89\u6170\u5242\u7ec4\u6ca1\u6709\u60a3\u8005\u5b9e\u73b0\u4e59\u809d\u8868\u9762\u6297\u539f\u6d88\u5931\u3002\u4e24\u7ec4\u60a3\u8005\u7684\u57fa\u7ebf\u4e59\u809d\u8868\u9762\u6297\u539f\u6c34\u5e73\u76f8\u5f53<\/i><\/p>\n
\u4e2d\u56fd\u676d\u5dde\u548c\u7ecd\u51742021\u5e7411\u670816\u65e5 \/\u7f8e\u901a\u793e\/ — \u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a1672\uff09\u4eca\u65e5\u5ba3\u5e03\u5176PD-L1\u6297\u4f53ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u7528\u4e8e\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u7684IIa\u671f\u548cIIb\u671f\u4e34\u5e8a\u7814\u7a76\u5165\u90092021\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u534f\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\uff08The Liver Meeting®<\/sup> 2021\uff09\u201c\u5927\u4f1a\u6700\u4f73\u6458\u8981\u5408\u96c6-\u75c5\u6bd2\u6027\u809d\u708e\u7c7b\u201d\u3002\u4e24\u9879\u4e34\u5e8a\u7814\u7a76\u7684\u4e3b\u8bb2\u4eba\u4eceAASLD\u4e3b\u5e2d\u5904\u83b7\u6089\u6b64\u8363\u8a89\uff0c\u5176\u8868\u793a\u201c…\u5165\u9009\u8be5\u8bba\u6587\u5408\u96c6\u662f\u4e00\u79cd\u6b8a\u8363\uff0c\u8868\u660e AASLD \u8bc4\u8bae\u59d4\u5458\u4f1a\u5bf9\u60a8\u7684\u7814\u7a76\u7ed9\u4e88\u4e86\u9ad8\u5ea6\u8bc4\u4ef7…\u3002\u201d<\/p>\n IIa\u671f\u548cIIb\u671f\u7814\u7a76\u7684\u91cd\u70b9\u662f\u4f7f\u7528\u76ae\u4e0b\u6ce8\u5c04PD-L1\u6297\u4f53ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u5b9e\u73b0\u6162\u6027\u4e59\u578b\u809d\u708e\uff08CHB\uff09\u7684\u529f\u80fd\u6027\u6cbb\u6108\u3002<\/p>\n \u8fd9\u4e24\u9879\u4e34\u5e8a\u7814\u7a76\u7684\u6807\u9898\u662f\uff1a\uff081\uff09\u76ae\u4e0b\u6ce8\u5c04PD-L1\u6297\u4f53ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u6cbb\u7597\u6162\u6027\u4e59\u578b\u809d\u708e\u60a3\u8005\u7684IIa\u671f\u8bd5\u9a8c\uff1b\u548c\uff082\uff09\u76ae\u4e0b\u6ce8\u5c04PD-L1\u6297\u4f53ASC22\uff08\u6069\u6c83\u5229\u5355\u6297\uff09\u8054\u5408\u6838\u82f7\uff08\u9178\uff09\u7c7b\u4f3c\u7269\u6cbb\u7597\u5728\u6162\u6027\u4e59\u578b\u809d\u708e\u60a3\u8005\u4e2d\u5b9e\u73b0\u4e59\u809d\u8868\u9762\u6297\u539f\u6d88\u5931\uff1aIIb\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e2d\u671f\u7ed3\u679c<\/p>\n \u201c\u975e\u5e38\u8363\u5e78\uff0cIIa\u671f\u548cIIb\u671f\u7814\u7a76\u5747\u5165\u9009\u2018\u5927\u4f1a\u6700\u4f73\u6458\u8981\u2019\uff0c\u8868\u660eAASLD\u8bc4\u8bae\u59d4\u5458\u4f1a\u80af\u5b9a\u4e86\u6211\u4eec\u9ad8\u8d28\u91cf\u7684\u7814\u7a76\uff0c\u4ee5\u53ca\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u9886\u57df\u5b58\u5728\u7684\u663e\u8457\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff0c\u201d \u6b4c\u793c\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5434\u52b2\u6893\u535a\u58eb\u8868\u793a\uff0c\u201cASC22\u5c06\u6709\u671b\u6210\u4e3a\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u7684\u57fa\u77f3\u514d\u75ab\u7597\u6cd5\u3002\u201d<\/p>\n \u5173\u4e8e\u6b4c\u793c<\/b><\/p>\n \u6b4c\u793c\u662f\u4e00\u5bb6\u5728\u9999\u6e2f\u8bc1\u5238\u4ea4\u6613\u6240\u4e0a\u5e02\uff081672.HK\uff09\u7684\u521b\u65b0\u7814\u53d1\u9a71\u52a8\u578b\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u6db5\u76d6\u4e86\u4ece\u65b0\u836f\u53d1\u73b0\u548c\u5f00\u53d1\u76f4\u5230\u751f\u4ea7\u548c\u5546\u4e1a\u5316\u7684\u5b8c\u6574\u4ef7\u503c\u94fe\u3002\u6b4c\u793c\u81f4\u529b\u4e8e\u75c5\u6bd2\u6027\u75be\u75c5\u3001\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\/\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u3001\u80bf\u7624\uff08\u53e3\u670d\u80bf\u7624\u4ee3\u8c22\u68c0\u67e5\u70b9\u4e0e\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\uff09\u7b49\u9886\u57df\u521b\u65b0\u836f\u7684\u7814\u53d1\u548c\u5546\u4e1a\u5316\uff0c\u4ee5\u89e3\u51b3\u56fd\u5185\u5916\u60a3\u8005\u4e34\u5e8a\u9700\u6c42\u3002\u5728\u5177\u5907\u6df1\u539a\u4e13\u4e1a\u77e5\u8bc6\u53ca\u4f18\u79c0\u8fc7\u5f80\u6210\u5c31\u7684\u7ba1\u7406\u56e2\u961f\u5e26\u9886\u4e0b\uff0c\u6b4c\u793c\u4ee5\u5168\u7403\u5316\u7684\u89c6\u91ce\u5e03\u5c40\u521b\u65b0\u836f\u7269\u7814\u53d1\u9886\u57df\uff0c\u7784\u51c6\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u5e76\u4ee5\u7814\u53d1\u8d5b\u9053\u56fd\u9645\u9886\u5148\u7684\u5b9a\u4f4d\uff0c\u9ad8\u6548\u3001\u5feb\u901f\u63a8\u8fdb\u7ba1\u7ebf\u4ea7\u54c1\u7684\u5f00\u53d1\u3002\u6b4c\u793c\u76ee\u524d\u62e5\u6709\u4e09\u4e2a\u5546\u4e1a\u5316\u4ea7\u54c1\u548c18\u6761\u5f3a\u5065\u4e14\u805a\u7126\u521b\u65b0\u7684\u7814\u53d1\u7ba1\u7ebf\uff0c\u4f17\u591a\u5728\u7814\u7ba1\u7ebf\u5904\u4e8e\u56fd\u9645\u9886\u5148\u7684\u5730\u4f4d\uff0c\u5e76\u79ef\u6781\u5e03\u5c40\u65b0\u7684\u6cbb\u7597\u9886\u57df\uff1a<\/p>\n 1. \u75c5\u6bd2\u6027\u75be\u75c5\uff1a\uff081\uff09\u4e59\u809d\uff08\u529f\u80fd\u6027\u6cbb\u6108\uff09\uff1a\u63a2\u7d22\u4ee5\u76ae\u4e0b\u6ce8\u5c04PD-L1\u6297\u4f53ASC22\u53ca\u6d3e\u7f57\u6b23®\u4e3a\u57fa\u77f3\u836f\u7269\uff0c\u4e0e\u5176\u4ed6\u9776\u70b9\u836f\u7269\u8054\u5408\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u6709\u671b\u4e3a\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u5e26\u6765\u91cd\u5927\u7a81\u7834\u3002\uff082\uff09\u827e\u6ecb\u75c5\uff1a\u514d\u75ab\u7597\u6cd5ASC22\uff0c\u7528\u4e8e\u827e\u6ecb\u75c5\u7279\u5f02\u6027\u514d\u75ab\u91cd\u5efa\uff0c\u4ee5\u671f\u5b9e\u73b0\u827e\u6ecb\u75c5\u611f\u67d3\u8005\u7684\u529f\u80fd\u6027\u6cbb\u6108\u3002\uff083\uff09\u4e19\u809d\uff1a\u6b4c\u793c\u6210\u529f\u7814\u53d1\u4e0a\u5e02\u7531\u4e24\u4e2a1\u7c7b\u65b0\u836f\u6208\u8bfa\u536b®\u548c\u65b0\u529b\u83b1®\u7ec4\u6210\u7684\u5168\u53e3\u670d\u4e19\u809d\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n 2. \u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\/\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff1a\u6b4c\u793c\u65d7\u4e0b\u5168\u8d44\u5b50\u516c\u53f8\u7518\u83b1\u5236\u836f\u4e13\u6ce8\u4e8e\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\u9886\u57df\u521b\u65b0\u836f\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u7518\u83b1\u5236\u836f\u6709\u4e09\u6b3e\u5206\u522b\u9488\u5bf9\u8102\u80aa\u9178\u5408\u6210\u9176\uff08FASN\uff09\u3001\u7532\u72b6\u817a\u6fc0\u7d20ß\u53d7\u4f53\uff08THRß\uff09\u53ca\u6cd5\u5c3c\u9187X\u53d7\u4f53\uff08FXR\uff09\u7684\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\u5019\u9009\u836f\u7269\u53ca\u4e09\u79cd\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u3002\u9488\u5bf9FXR\u9776\u70b9\u7684\u65b0\u836f\u540c\u65f6\u88ab\u5f00\u53d1\u7528\u4e8e\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u7684\u6cbb\u7597\u3002<\/p>\n 3. 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