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\u5173\u4e8eALK-1\u5355\u6297<\/p>\n
ALK-1\u5355\u6297\u662f\u4e00\u79cd\u5168\u4eba\u6e90IgG2\u4e2d\u548c\u6297\u4f53\uff0c\u53ef\u6291\u5236ALK-1\/ TGF-\u03b2\u4fe1\u53f7\u8f6c\u5bfc\u548c\u80bf\u7624\u8840\u7ba1\u751f\u6210\uff0c\u662f\u5f00\u62d3\u836f\u4e1a\u4e8e2018\u5e74\u81ea\u8f89\u745e\u53d6\u5f97\u5728\u6240\u6709\u7624\u79cd\u9886\u57df\u7684\u72ec\u5bb6\u5168\u7403\u8bb8\u53ef\u7684\u6f5c\u5728\u540c\u7c7b\u9996\u521b\u6297\u4f53\u3002<\/p>\n
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\u5173\u4e8eKN046<\/p>\n
KN046\u662f\u5eb7\u5b81\u6770\u745e\u81ea\u4e3b\u7814\u53d1\u7684PD-L1\/CTLA-4\u53cc\u7279\u5f02\u6027\u6297\u4f53\uff0c\u5176\u521b\u65b0\u8bbe\u8ba1\u5305\u62ec\uff1a\u91c7\u7528\u673a\u5236\u4e0d\u540c\u7684CTLA-4\u4e0ePD-L1\u5355\u57df\u6297\u4f53\u878d\u5408\u7ec4\u6210\uff1b\u53ef\u9776\u5411\u5bcc\u96c6\u4e8ePD-L1\u9ad8\u8868\u8fbe\u7684\u80bf\u7624\u5fae\u73af\u5883\u53ca\u6e05\u9664\u6291\u5236\u80bf\u7624\u514d\u75ab\u7684Treg\u3002<\/p>\n
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