{"id":48819,"date":"2021-10-20T18:00:00","date_gmt":"2021-10-20T11:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021102018000048819"},"modified":"2021-10-21T17:56:39","modified_gmt":"2021-10-21T09:56:39","slug":"%e7%99%be%e6%b5%8e%e7%a5%9e%e5%b7%9e%e5%92%8cnanolek%e5%ae%a3%e5%b8%83%e7%99%be%e6%82%a6%e6%b3%bdr%ef%bc%88%e6%b3%bd%e5%b8%83%e6%9b%bf%e5%b0%bc%ef%bc%89%e5%9c%a8%e4%bf%84%e7%bd%97%e6%96%af%e8%8e%b7","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021102018000048819","title":{"rendered":"\u767e\u6d4e\u795e\u5dde\u548cNanolek\u5ba3\u5e03\u767e\u60a6\u6cfd(R)\uff08\u6cfd\u5e03\u66ff\u5c3c\uff09\u5728\u4fc4\u7f57\u65af\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\u60a3\u8005"},"content":{"rendered":"<p><p><span class=\"xn-subheadline\">\u8fd9\u662f\u767e\u60a6\u6cfd\u00ae\u5728\u4fc4\u7f57\u65af\u53d6\u5f97\u7684\u9996\u6b21\u836f\u653f\u6279\u51c6<\/span><\/p>\n<p><span class=\"xn-subheadline\">\u76ee\u524d\u767e\u60a6\u6cfd\u00ae\u5df2\u572810\u4e2a\u56fd\u5bb6\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff0c\u5305\u62ec\u7f8e\u56fd\u3001\u4e2d\u56fd\u3001\u52a0\u62ff\u5927\u3001\u6fb3\u5927\u5229\u4e9a\u548c\u5176\u5b83\u56fd\u5bb6<\/span><\/p>\n<p><span class=\"xn-subheadline\">\u767e\u6d4e\u795e\u5dde\u81f4\u529b\u4e8e\u901a\u8fc7\u81ea\u4e3b\u7533\u62a5\u6216\u4e0e\u6218\u7565\u4f19\u4f34\u5408\u4f5c\uff0c\u5feb\u901f\u63a8\u8fdb\u767e\u60a6\u6cfd\u00ae\u5728\u5168\u7403\u7684\u6ce8\u518c<\/span><\/p>\n<p><span class=\"xn-subheadline\">\u57fa\u4e8e\u72ec\u5bb6\u5206\u9500\u534f\u8bae\uff0cNanolek\u5c06\u5728\u4fc4\u7f57\u65af\u8d1f\u8d23\u767e\u60a6\u6cfd\u00ae\u7684\u5546\u4e1a\u5316<\/span><\/p>\n<p>\u4e2d\u56fd\u5317\u4eac\u3001\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u548c\u83ab\u65af\u79d12021\u5e7410\u670820\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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Vladimirovna Poddubnaya\u6559\u6388\u8868\u793a\u3002<\/p>\n<p>\u767e\u6d4e\u795e\u5dde\u8840\u6db2\u5b66\u9996\u5e2d\u533b\u5b66\u5b98\u9ec4\u851a\u5a1f\u533b\u5b66\u535a\u58eb\u8868\u793a\uff1a\u201c\u6b64\u6b21\u6279\u51c6\u518d\u6b21\u5370\u8bc1\u4e86\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u4f5c\u4e3a\u4e00\u9879\u6f5c\u5728\u7684\u2018\u540c\u7c7b\u6700\u4f18\u2019BTK\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u8840\u6db2\u6076\u6027\u80bf\u7624\u7684\u6f5c\u529b\u3002\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e3a\u4fc4\u7f57\u65afMCL\u60a3\u8005\u5e26\u53bb\u8fd9\u4e00\u836f\u7269\u3002\u767e\u6d4e\u795e\u5dde\u4e00\u76f4\u81f4\u529b\u4e8e\u4e3a\u5168\u7403\u5404\u5730\u7684\u60a3\u8005\u6539\u5584\u4e34\u5e8a\u83b7\u76ca\uff0c\u800c\u4eca\u5e74\u622a\u81f3\u76ee\u524d\u4e3a\u6b62\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5df2\u7ecf\u5728\u5305\u62ec\u7f8e\u56fd\u3001\u52a0\u62ff\u5927\u3001\u62c9\u4e01\u7f8e\u6d32\u4ee5\u53caAPAC\u548cEMEA\u5730\u533a\u83b7\u5f97\u4e8612\u9879\u836f\u653f\u6279\u51c6\u3002\u201d<\/p>\n<p>\u767e\u6d4e\u795e\u5dde\u4fc4\u7f57\u65af\u65b0\u5e02\u573a\u5f00\u53d1\u56e2\u961f\u9ad8\u7ea7\u603b\u76d1Vitaly Sokolinsky\u8868\u793a\uff1a\u201c\u6211\u4eec\u671f\u5f85\u4e0eNanolek\u4e00\u9053\uff0c\u5c06\u8fd9\u4e00\u4e34\u5e8a\u6025\u9700\u7684\u65b0\u7597\u6cd5\u5e26\u7ed9\u4fc4\u7f57\u65af\u7684MCL\u60a3\u8005\u3002\u767e\u6d4e\u795e\u5dde\u6b63\u5728\u4fc4\u7f57\u65af\u3001\u6b27\u6d32\u7b49\u5730\u533a\u79ef\u6781\u62d3\u5c55\uff0c\u5c06\u6211\u4eec\u7684\u4e13\u4e1a\u7ecf\u9a8c\u548c\u6210\u679c\u5e26\u5411\u5168\u7403\u66f4\u591a\u7684\u65b0\u5e02\u573a\uff0c\u6b64\u6b21\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u4fc4\u7f57\u65af\u53d6\u5f97MCL\u7684\u83b7\u6279\uff0c\u6b63\u662f\u8fd9\u4e9b\u5de5\u4f5c\u6210\u679c\u7684\u6709\u529b\u4f53\u73b0\u3002\u201d<\/p>\n<p>Nanolek\u516c\u53f8\u603b\u88c1Vladimir&nbsp;Khristenko\u8868\u793a\uff1a\u201c\u6b64\u6b21\u7684\u83b7\u6279\u662f\u4e3a\u60a3\u8005\u8c0b\u6c42\u798f\u7949\u7684\u91cd\u8981\u91cc\u7a0b\u7891\uff0c\u6211\u4eec\u4e3a\u6b64\u611f\u5230\u81ea\u8c6a\u3002\u6211\u4eec\u671f\u5f85\u901a\u8fc7\u4e0e\u767e\u6d4e\u795e\u5dde\u7684\u5f3a\u5f3a\u8054\u624b\uff0c\u63a8\u52a8\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u60e0\u53ca\u5168\u7403\u60a3\u8005\u3002\u6211\u4eec\u53cc\u65b9\u5c06\u901a\u529b\u534f\u4f5c\uff0c\u4e3a\u4fc4\u7f57\u65af\u7684\u764c\u75c7\u60a3\u8005\u63d0\u4f9b\u521b\u65b0\u7597\u6cd5\u3002\u201d<\/p>\n<p>\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u4fc4\u7f57\u65af\u7528\u4e8e\u6cbb\u7597MCL\u7684\u4e0a\u5e02\u8bb8\u53ef\u662f\u57fa\u4e8e\u4e24\u9879\u5355\u81c2\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7ed3\u679c\u3002\u5728\u8fd9\u4e24\u9879\u8bd5\u9a8c\u4e2d\uff0c\u7531\u72ec\u7acb\u5ba1\u67e5\u59d4\u5458\u4f1a\uff08IRC\uff09\u6839\u636e2014 Lugano\u5206\u7c7b\u6807\u51c6\u8bc4\u4f30\u7684\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u603b\u7f13\u89e3\u7387\uff08ORR\uff09\u4e3a83.7%\uff0cORR\u5b9a\u4e49\u4e3a\u5b8c\u5168\u7f13\u89e3\uff08CR\uff09\u548c\u90e8\u5206\u7f13\u89e3\uff08PR\uff09\u7387\u7684\u603b\u548c\u3002<\/p>\n<p>\u5728118\u4f8b\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u6cbb\u7597\u7684MCL\u60a3\u8005\u4e2d\uff0c\u5728\u63a5\u53d7\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u6cbb\u7597\u540e\uff0c36\u4f8b\u60a3\u8005\uff0831%\uff09\u60a3\u8005\u51fa\u73b0\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\uff0c\u5176\u4e2d\u6700\u5e38\u89c1\u4e0d\u826f\u4e8b\u4ef6\u4e3a\u611f\u67d3\u6027\u80ba\u708e\uff0811%\uff09\u548c\u51fa\u8840\uff085%\uff09\u30028\u4f8b\u60a3\u8005\uff087%\uff09\u56e0\u8bd5\u9a8c\u671f\u95f4\u51fa\u73b0\u7684\u4e0d\u826f\u53cd\u5e94\u800c\u7ec8\u6b62\u6cbb\u7597\uff0c\u5176\u4e2d\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u4e8b\u4ef6\u4e3a\u611f\u67d3\u6027\u80ba\u708e\uff083.4%\uff09\uff0c1\u4f8b\u60a3\u8005\uff080.8%\uff09\u7531\u4e8e\u4e0d\u826f\u53cd\u5e94\u51cf\u5c11\u7528\u836f\u5242\u91cf\u3002<\/p>\n<p>\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u7684\u63a8\u8350\u5242\u91cf\u4e3a160 mg\u6bcf\u65e5\u4e24\u6b21\u6216320 mg\u6bcf\u65e5\u4e00\u6b21\uff0c\u7a7a\u8179\u6216\u9910\u540e\u53e3\u670d\u5747\u53ef\u3002\u7528\u836f\u5242\u91cf\u53ef\u6839\u636e\u4e0d\u826f\u53cd\u5e94\u8c03\u6574\uff0c\u91cd\u5ea6\u809d\u635f\u5bb3\u548c\u6b63\u5728\u670d\u7528\u4e0e\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5b58\u5728\u6f5c\u5728\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u7684\u60a3\u8005\u53ef\u964d\u4f4e\u5242\u91cf\u3002<\/p>\n<p><b>\u5173\u4e8e\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08<\/b><b>MCL<\/b><b>\uff09<\/b><b>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/b><\/p>\n<p>MCL\u662f\u4e00\u79cd\u7f55\u89c1\u7684\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08NHL\uff09\uff0c\u53d1\u751f\u5728\u6dcb\u5df4\u7ed3\u5916\u7f18\uff08\u5373\u201c\u5957\u533a\u201d\uff09<span id=\"spanHghlt8035\"><sup>[1]<\/sup>\uff0c<\/span>MCL\u60a3\u8005\u7ea6\u5360\u6240\u6709NHL\u75c5\u4f8b\u76845%<sup><span id=\"spanHghlt995b\">[1]<\/span><\/sup>\u3002MCL\u5728\u7537\u6027\u4e2d\u7684\u53d1\u751f\u7387\u9ad8\u4e8e\u5973\u6027<sup><span id=\"spanHghltf463\">[1]<\/span><\/sup>\uff0c\u8bb8\u591aMCL\u60a3\u8005\u662f\u572860\u5c81\u5de6\u53f3\u65f6\u88ab\u786e\u8bca<sup><span id=\"spanHghltcbe3\">[1]<\/span><\/sup>\u3002MCL\u60a3\u8005\u9884\u540e\u8f83\u5dee\uff0c\u4e2d\u4f4d\u751f\u5b58\u671f\u4e3a3\u81f34\u5e74\uff0c\u4e14\u5f80\u5f80\u5728\u75be\u75c5\u665a\u671f\u624d\u5f97\u5230\u786e\u8bca<sup><span id=\"spanHghlt706a\">[2]<\/span><\/sup>\u3002\u5728\u4fc4\u7f57\u65af\uff0c\u6bcf\u5e74\u65b0\u589e\u7684MCL\u75c5\u4f8b\u8d85\u8fc71000\u4f8b<sup>[<span id=\"spanHghlt0e01\">3]<\/span><\/sup>\u3002<\/p>\n<p><b>\u5173\u4e8e\u767e\u60a6\u6cfd<\/b><b><sup>&reg;<\/sup><\/b><b>\uff08\u6cfd\u5e03\u66ff\u5c3c\uff09<\/b><\/p>\n<p>\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\uff08\u6cfd\u5e03\u66ff\u5c3c\uff09\u662f\u4e00\u6b3e\u7531\u767e\u6d4e\u795e\u5dde\u79d1\u5b66\u5bb6\u81ea\u4e3b\u7814\u53d1\u7684\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u5c0f\u5206\u5b50\u6291\u5236\u5242\uff0c\u76ee\u524d\u6b63\u5728\u5168\u7403\u8fdb\u884c\u5e7f\u6cdb\u7684\u4e34\u5e8a\u8bd5\u9a8c\u9879\u76ee\uff0c\u4f5c\u4e3a\u5355\u836f\u548c\u4e0e\u5176\u4ed6\u7597\u6cd5\u8fdb\u884c\u8054\u5408\u7528\u836f\u6cbb\u7597\u591a\u79cdB\u7ec6\u80de\u6076\u6027\u80bf\u7624\u3002\u7531\u4e8e\u65b0\u7684BTK\u4f1a\u5728\u4eba\u4f53\u5185\u4e0d\u65ad\u5408\u6210\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u7684\u8bbe\u8ba1\u901a\u8fc7\u4f18\u5316\u751f\u7269\u5229\u7528\u5ea6\u3001\u534a\u8870\u671f\u548c\u9009\u62e9\u6027\uff0c\u5b9e\u73b0\u5bf9BTK\u86cb\u767d\u5b8c\u5168\u3001\u6301\u7eed\u5730\u6291\u5236\u3002\u51ed\u501f\u4e0e\u5176\u4ed6\u83b7\u6279BTK\u6291\u5236\u5242\u5b58\u5728\u5dee\u5f02\u5316\u7684\u836f\u4ee3\u52a8\u529b\u5b66\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u80fd\u5728\u591a\u4e2a\u75be\u75c5\u76f8\u5173\u7ec4\u7ec7\u4e2d\u6291\u5236\u6076\u6027B\u7ec6\u80de\u589e\u6b96\u3002<\/p>\n<p>\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5df2\u5728\u4ee5\u4e0b\u5730\u533a\u4e2d\u83b7\u6279\u5982\u4e0b\u9002\u5e94\u75c7\uff1a<\/p>\n<ul type=\"disc\">\n<li>2019\u5e7411\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u7f8e\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u7597\u6cd5\u7684\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005*\uff1b <\/li>\n<li>2020\u5e746\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u4e2d\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005**\uff1b <\/li>\n<li>2020\u5e746\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u4e2d\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08CLL\uff09\u6216\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08SLL\uff09&nbsp;\u60a3\u8005**\uff1b <\/li>\n<li>2021\u5e742\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u963f\u62c9\u4f2f\u8054\u5408\u914b\u957f\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027MCL\u60a3\u8005\uff1b <\/li>\n<li>2021\u5e743\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u52a0\u62ff\u5927\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u534e\u6c0f\u5de8\u7403\u86cb\u767d\u8840\u75c7\uff08WM\uff09\u6210\u5e74\u60a3\u8005\uff1b <\/li>\n<li>2021\u5e746\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u4e2d\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u534e\u6c0f\u5de8\u7403\u86cb\u767d\u8840\u75c7\uff08WM\uff09\u60a3\u8005**\uff1b&nbsp; <\/li>\n<li>2021\u5e747\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u52a0\u62ff\u5927\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005\uff1b <\/li>\n<li>2021\u5e747\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u667a\u5229\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005\uff1b <\/li>\n<li>2021\u5e748\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u5df4\u897f\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005\uff1b <\/li>\n<li>2021\u5e748\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u7f8e\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u6210\u5e74\u534e\u6c0f\u5de8\u7403\u86cb\u767d\u8840\u75c7\uff08WM\uff09\u60a3\u8005\uff1b&nbsp; <\/li>\n<li>2021\u5e749\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u7f8e\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u57fa\u4e8e\u6297CD20\u65b9\u6848\u7684\u8fb9\u7f18\u533a\u6dcb\u5df4\u7624\uff08MZL\uff09\u6210\u4eba\u60a3\u8005*\uff1b <\/li>\n<li>2021\u5e7410\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u65b0\u52a0\u5761\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005\uff1b&nbsp; <\/li>\n<li>2021\u5e7410\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u4ee5\u8272\u5217\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005\uff1b <\/li>\n<li>2021\u5e7410\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u6fb3\u5927\u5229\u4e9a\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u534e\u6c0f\u5de8\u7403\u86cb\u767d\u8840\u75c7\uff08WM\uff09\u60a3\u8005\uff0c\u6216\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u4e0d\u9002\u5408\u63a5\u53d7\u514d\u75ab\u5316\u7597\u7684\u6210\u5e74WM\u60a3\u8005\uff1b&nbsp; <\/li>\n<li>2021\u5e7410\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u6fb3\u5927\u5229\u4e9a\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005\uff1b <\/li>\n<li>2021\u5e7410\u6708\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5728\u4fc4\u7f57\u65af\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cd\u6cbb\u7597\u7684\u6210\u5e74\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09\u60a3\u8005\u3002&nbsp;<\/li>\n<\/ul>\n<p>\u8fc4\u4eca\u4e3a\u6b62\uff0c\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\u5df2\u9012\u4ea4\u8d85\u8fc730\u9879\u9488\u5bf9\u591a\u9879\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u7533\u8bf7\uff0c\u8986\u76d6\u7f8e\u56fd\u3001\u4e2d\u56fd\u3001\u6b27\u76df\u548c\u5176\u4ed620\u591a\u4e2a\u56fd\u5bb6\u6216\u5730\u533a\u3002<\/p>\n<p>*\u8be5\u9879\u9002\u5e94\u75c7\u57fa\u4e8e\u603b\u7f13\u89e3\u7387\uff08ORR\uff09\u83b7\u5f97\u52a0\u901f\u6279\u51c6\u3002\u9488\u5bf9\u8be5\u9002\u5e94\u75c7\u7684\u5b8c\u5168\u6279\u51c6\u5c06\u53d6\u51b3\u4e8e\u9a8c\u8bc1\u6027\u8bd5\u9a8c\u4e2d\u4e34\u5e8a\u76ca\u5904\u7684\u9a8c\u8bc1\u548c\u63cf\u8ff0\u3002<\/p>\n<p>**\u8be5\u9879\u9002\u5e94\u75c7\u83b7\u9644\u6761\u4ef6\u6279\u51c6\u3002\u9488\u5bf9\u8be5\u9002\u5e94\u75c7\u7684\u5b8c\u5168\u6279\u51c6\u5c06\u53d6\u51b3\u4e8e\u6b63\u5728\u5f00\u5c55\u7684\u786e\u8bc1\u6027\u968f\u673a\u3001\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\u3002<\/p>\n<p><b>\u5173\u4e8e\u767e\u6d4e\u795e\u5dde\u80bf\u7624\u5b66<\/b><\/p>\n<p>\u767e\u6d4e\u795e\u5dde\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\u6216\u4e0e\u5fd7\u540c\u9053\u5408\u7684\u5408\u4f5c\u4f19\u4f34\u643a\u624b\uff0c\u4e0d\u65ad\u63a8\u52a8\u540c\u7c7b\u6700\u4f73\u6216\u540c\u7c7b\u7b2c\u4e00\u7684\u4e34\u5e8a\u5019\u9009\u836f\u7269\u7814\u53d1\uff0c\u81f4\u529b\u4e8e\u4e3a\u5168\u7403\u60a3\u8005\u63d0\u4f9b\u6709\u5f71\u54cd\u529b\u3001\u53ef\u53ca\u4e14\u53ef\u8d1f\u62c5\u7684\u836f\u7269\u3002\u516c\u53f8\u5168\u7403\u4e34\u5e8a\u7814\u7a76\u548c\u5f00\u53d1\u56e2\u961f\u5df2\u6709\u7ea62300\u4eba\uff0c\u56e2\u961f\u89c4\u6a21\u8fd8\u5728\u4e0d\u65ad\u6269\u5927\u3002\u8fd9\u652f\u56e2\u961f\u76ee\u524d\u6b63\u5728\u5168\u7403\u8303\u56f4\u652f\u6301\u5f00\u5c5590\u591a\u9879\u4e34\u5e8a\u7814\u7a76\uff0c\u5df2\u62db\u52df\u60a3\u8005\u548c\u5065\u5eb7\u53d7\u8bd5\u8005\u8d85\u8fc713000\u4eba\u3002\u767e\u6d4e\u795e\u5dde\u81ea\u6709\u7684\u4e34\u5e8a\u5f00\u53d1\u56e2\u961f\u89c4\u5212\u5e76\u4e3b\u5bfc\u516c\u53f8\u4ea7\u54c1\u7ba1\u7ebf\u7684\u7814\u53d1\u548c\u6269\u5145\uff0c\u4e3a\u8986\u76d6\u5168\u740340\u591a\u4e2a\u56fd\u5bb6\/\u5730\u533a\u7684\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u652f\u6301\u548c\u6307\u5bfc\u3002\u76ee\u524d\uff0c\u767e\u6d4e\u795e\u5dde\u81ea\u4e3b\u7814\u53d1\u7684\u4e09\u6b3e\u836f\u7269\u5df2\u83b7\u6279\u4e0a\u5e02\uff1a\u767e\u60a6\u6cfd<sup>&reg;<\/sup>\uff08BTK\u6291\u5236\u5242\uff0c\u5df2\u5728\u7f8e\u56fd\u3001\u4e2d\u56fd\u3001\u52a0\u62ff\u5927\u3001\u6fb3\u5927\u5229\u4e9a\u53ca\u5176\u4ed6\u56fd\u9645\u5e02\u573a\u83b7\u6279\u4e0a\u5e02\uff09\u3001\u767e\u6cfd\u5b89<sup>&reg;<\/sup>\uff08\u53ef\u6709\u6548\u907f\u514dFc-\u03b3\u53d7\u4f53\u7ed3\u5408\u7684\u6297PD-1\u6297\u4f53\uff0c\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff09\u53ca\u767e\u6c47\u6cfd<sup>&reg;<\/sup>\uff08\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff09\u3002\u767e\u6d4e\u795e\u5dde\u62e5\u6709\u4e00\u652f\u8ffd\u6c42\u9ad8\u54c1\u8d28\u4e0e\u521b\u65b0\u3001\u7acb\u8db3\u79d1\u5b66\u4e0e\u533b\u5b66\u7684\u56e2\u961f\uff0c\u5e76\u5728\u4e2d\u56fd\u5efa\u7acb\u4e86\u9886\u5148\u5730\u4f4d\uff0c\u6253\u9020\u4e86\u4e00\u652f\u89c4\u6a21\u5e9e\u5927\u3001\u805a\u7126\u4e8e\u80bf\u7624\u5b66\u7684\u5546\u4e1a\u56e2\u961f\u3002<\/p>\n<p>\u540c\u65f6\uff0c\u767e\u6d4e\u795e\u5dde\u8fd8\u4e0e\u5176\u4ed6\u521b\u65b0\u516c\u53f8\u5408\u4f5c\uff0c\u5171\u540c\u643a\u624b\u63a8\u8fdb\u521b\u65b0\u7597\u6cd5\u7684\u7814\u53d1\uff0c\u4ee5\u6ee1\u8db3\u5168\u7403\u5065\u5eb7\u9700\u6c42\u3002\u5728\u4e2d\u56fd\uff0c\u767e\u6d4e\u795e\u5dde\u6b63\u5728\u9500\u552e\u591a\u6b3e\u7531\u5b89\u8fdb\u548c\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u6388\u6743\u7684\u80bf\u7624\u836f\u7269\u3002\u516c\u53f8\u4e5f\u901a\u8fc7\u4e0e\u5305\u62ec\u5b89\u8fdb\u3001\u767e\u5965\u6cf0\u3001EUSA Pharma\u3001Mirati Therapeutics\u3001Seagen \u4ee5\u53ca&nbsp;Zymeworks \u5728\u5185\u7684\u591a\u5bb6\u516c\u53f8\u5408\u4f5c\uff0c\u66f4\u5927\u7a0b\u5ea6\u6ee1\u8db3\u5f53\u524d\u5168\u7403\u8303\u56f4\u5c1a\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u767e\u6d4e\u795e\u5dde\u8fd8\u4e0e\u8bfa\u534e\u516c\u53f8\u8fbe\u6210\u5408\u4f5c\uff0c\u6388\u6743\u8bfa\u534e\u5728\u5317\u7f8e\u3001\u6b27\u6d32\u548c\u65e5\u672c\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u5546\u4e1a\u5316\u767e\u6cfd\u5b89<sup>&reg;<\/sup>\u3002<\/p>\n<p><b>\u5173\u4e8e\u767e\u6d4e\u795e\u5dde<\/b><\/p>\n<p>\u767e\u6d4e\u795e\u5dde\u662f\u4e00\u5bb6\u7acb\u8db3\u79d1\u5b66\u7684\u5168\u7403\u6027\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u521b\u65b0\u3001\u53ef\u8d1f\u62c5\u7684\u836f\u7269\uff0c\u4ee5\u4e3a\u5168\u7403\u60a3\u8005\u6539\u5584\u6cbb\u7597\u6548\u679c\u548c\u63d0\u9ad8\u836f\u7269\u53ef\u53ca\u6027\u3002\u76ee\u524d\u516c\u53f8\u5e7f\u6cdb\u7684\u836f\u7269\u7ec4\u5408\u5305\u62ec40\u591a\u6b3e\u4e34\u5e8a\u5019\u9009\u836f\u7269\u3002\u516c\u53f8\u901a\u8fc7\u52a0\u5f3a\u81ea\u4e3b\u7814\u53d1\u80fd\u529b\u548c\u5408\u4f5c\uff0c\u52a0\u901f\u63a8\u8fdb\u591a\u5143\u3001\u521b\u65b0\u7684\u836f\u7269\u7ba1\u7ebf\u5f00\u53d1\u3002\u6211\u4eec\u81f4\u529b\u4e8e\u57282030\u5e74\u524d\u4e3a\u5168\u740320\u591a\u4ebf\u4eba\u5168\u9762\u6539\u5584\u836f\u7269\u53ef\u53ca\u6027\u3002\u767e\u6d4e\u795e\u5dde\u5728\u5168\u7403\u4e94\u5927\u6d32\u6253\u9020\u4e86\u4e00\u652f7000\u591a\u4eba\u7684\u56e2\u961f\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u5b98\u7f51<a target=\"_blank\" href=\"http:\/\/www.beigene.com.cn\/\" rel=\"nofollow noopener\">www.beigene.com.cn<\/a>\u3002<\/p>\n<p><b>\u5173\u4e8eNanolek<\/b><\/p>\n<p>Nanolek\u662f\u4e00\u5bb6\u4fc4\u7f57\u65af\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u7531Vladimir Khristenko\u548cMikhail Nekrasov\u4e8e2011\u5e74\u521b\u5efa\u3002\u516c\u53f8\u81f4\u529b\u4e8e\u901a\u8fc7\u81ea\u4e3b\u7814\u53d1\uff0c\u6216\u4e0e\u5408\u4f5c\u4f19\u4f34\u5171\u540c\u751f\u4ea7\u8fdb\u53e3\u4eff\u5236\u836f\u548c\u521b\u65b0\u836f\u3002&nbsp;Nanolek\u662f\u4fc4\u7f57\u65af\u513f\u7ae5\u75ab\u82d7\u751f\u4ea7\u7684\u9886\u519b\u4f01\u4e1a\u4e4b\u4e00\u3002&nbsp;\u76ee\u524d\uff0cNanolek\u7684\u4ea7\u54c1\u7ec4\u5408\u4e2d\u5df2\u670920\u79cd\u836f\u7269\uff0c\u6b64\u5916\u8fd8\u670935\u79cd\u836f\u7269\u5904\u4e8e\u4e0a\u5e02\u8fdb\u7a0b\u4e2d\u7684\u4e0d\u540c\u9636\u6bb5\uff0c\u8ba1\u5212\u4e8e\u672a\u67655\u5e74\u5185\u4e0a\u5e02\u3002\u516c\u53f8\u7684\u5de5\u5382\u4e8e2014\u5e74\u5728\u57fa\u7f57\u592b\u5730\u533a\u542f\u7528\uff0c\u8be5\u5de5\u5382\u5f15\u5165\u56fd\u9645\u6807\u51c6\u64cd\u4f5c\u548c\u6280\u672f\uff0c\u751f\u4ea7\u8bbe\u65bd\u9664\u7ecfGMP\u8ba4\u8bc1\u5916\uff0c\u4e5f\u5b9a\u671f\u901a\u8fc7\u5927\u578b\u56fd\u9645\u5236\u836f\u516c\u53f8\u7684\u8d28\u91cf\u7a3d\u67e5\uff0c\u4e0e\u8d5b\u8bfa\u83f2\u3001\u6768\u68ee\u3001\u9ed8\u514b\u548cAspen\u7b49\u516c\u53f8\u5408\u4f5c\u751f\u4ea7\u836f\u7269\u3002&nbsp;<\/p>\n<p>Nanolek\u4e5f\u4e0eRSOH\uff08\u4fc4\u7f57\u65af\u80bf\u7624\u8840\u6db2\u5b66\u5bb6\u5b66\u4f1a\uff09\u79ef\u6781\u5408\u4f5c\uff0c\u63a8\u52a8\u79d1\u5b66\u6559\u80b2\u3002\u9488\u5bf9CLL\u3001\u534e\u6c0f\u5de8\u7403\u86cb\u767d\u8840\u75c7\u548c\u8fb9\u7f18\u533a\u7ec6\u80de\u6dcb\u5df4\u7624\u8fd9\u51e0\u9879\u516c\u53f8\u62df\u7533\u8bf7\u7684\u9002\u5e94\u75c7\uff0cNanolek\u4e5f\u4e3a\u8840\u6db2\u5b66\u533b\u751f\u63d0\u4f9b\u4e86\u7ee7\u7eed\u6559\u80b2\u9879\u76ee\u3002\u516c\u53f8\u5b98\u7f51\uff1a<a target=\"_blank\" href=\"http:\/\/www.nanolek.ru.\/\" rel=\"nofollow noopener\">www.nanolek.ru.<\/a>&nbsp;<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u5305\u542b\u6839\u636e\u300a1995\u5e74\u79c1\u4eba\u8bc1\u5238\u8bc9\u8bbc\u6539\u9769\u6cd5\u6848\u300b\uff08Private Securities Litigation Reform Act of 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id=\"spanHghltcace\">[1]<\/span><\/sup> Lymphoma Research Foundation. Understanding Mantle Cell Lymphoma. Available at <a target=\"_blank\" href=\"https:\/\/lymphoma.org\/wp-content\/uploads\/2018\/10\/MantleCellLymphomaFact-Sheet.pdf\" rel=\"nofollow noopener\">https:\/\/lymphoma.org\/wp-content\/uploads\/2018\/10\/MantleCellLymphomaFact-Sheet.pdf<\/a> Accessed <span class=\"xn-chron\">October 2021<\/span>.<\/p>\n<p><sup><span id=\"spanHghlt199e\">[2]<\/span><\/sup> <span class=\"xn-person\">Philip J. Bierman<\/span>, <span class=\"xn-person\">James O. Armitage<\/span>, in Goldman&#8217;s <span class=\"xn-person\">Cecil Medicine<\/span> (Twenty Fourth Edition), 2012.<\/p>\n<p><span id=\"spanHghlt9f76\"><sup>[3]<\/sup> <\/span><a target=\"_blank\" href=\"https:\/\/glavonco.ru\/cancer_register\/%D0%9F%D0%BE%D0%BC%D0%BE%D1%89%D1%8C%202019.pdf\" rel=\"nofollow noopener\">https:\/\/glavonco.ru\/cancer_register\/%D0%9F%D0%BE%D0%BC%D0%BE%D1%89%D1%8C%202019.pdf<\/a>. Accessed <span class=\"xn-chron\">October 2021<\/span> <\/p>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>http:\/\/www.beigene.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8fd9\u662f\u767e\u60a6\u6cfd\u00ae\u5728\u4fc4\u7f57\u65af\u53d6\u5f97\u7684\u9996\u6b21\u836f\u653f\u6279\u51c6 \u76ee\u524d\u767e\u60a6\u6cfd\u00ae\u5df2\u572810\u4e2a\u56fd\u5bb6\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff0c\u5305\u62ec\u7f8e\u56fd\u3001\u4e2d\u56fd\u3001\u52a0\u62ff\u5927\u3001\u6fb3\u5927\u5229\u4e9a\u548c\u5176\u5b83\u56fd\u5bb6 \u767e\u6d4e\u795e\u5dde\u81f4\u529b\u4e8e\u901a\u8fc7\u81ea\u4e3b\u7533\u62a5\u6216\u4e0e\u6218\u7565\u4f19\u4f34\u5408\u4f5c\uff0c\u5feb\u901f\u63a8\u8fdb\u767e\u60a6\u6cfd\u00ae\u5728\u5168\u7403\u7684\u6ce8\u518c \u57fa\u4e8e\u72ec\u5bb6\u5206\u9500\u534f\u8bae\uff0cNanolek\u5c06\u5728\u4fc4\u7f57\u65af\u8d1f\u8d23\u767e\u60a6\u6cfd\u00ae\u7684\u5546\u4e1a\u5316 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