\u5317\u4eac2021\u5e7410\u670813\u65e5 \/\u7f8e\u901a\u793e\/ — \u8fd1\u65e5\uff0c\u5148\u745e\u8fbe\u79d1\u5b66\u987e\u95ee\u59d4\u5458\u4f1a\u518d\u8fce4\u4f4d\u5168\u7403\u9876\u5c16\u533b\u7597\u4e13\u5bb6\u52a0\u5165\uff0c\u5176\u4e2d3\u4f4d\u4f1a\u62c5\u4efb\u5148\u745e\u8fbeAcoArt\u819d\u4e0b\u836f\u7269\u6d82\u5c42\u7403\u56ca\uff08BTK\uff09\u7f8e\u56fd\u6ce8\u518c\u4e34\u5e8aPI\u3002\u65b0\u52a0\u5165\u7684\u4e13\u5bb6\u5305\u62ecPeter Schneider\u6559\u6388\u3001Matthew T. Menard\u535a\u58eb\u3001Sahil A. Parikh\u535a\u58eb\u53caThomas Zeller\u6559\u6388\uff0c4\u4f4d\u4e13\u5bb6\u5c06\u6307\u5bfc\u5148\u745e\u8fbe\u7684\u6838\u5fc3\u4ea7\u54c1\u5728\u7f8e\u56fd\u548c\u6b27\u6d32\u7b49\u5730\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u5e76\u5728\u540e\u671f\u7684\u4ea7\u54c1\u6ce8\u518c\u83b7\u6279\u4e2d\u63d0\u4f9b\u5e2e\u52a9\uff0c\u52a0\u901f\u5916\u5468\u4ecb\u5165\u521b\u65b0\u4ea7\u54c1\u7684\u4e34\u5e8a\u843d\u5730\u3002\u540c\u65f6\uff0c\u4ed6\u4eec\u5c06\u51ed\u501f\u81ea\u8eab\u5728\u5916\u5468\u4ecb\u5165\u9886\u57df\u7684\u4e13\u4e1a\u6743\u5a01\uff0c\u6307\u5bfc\u5148\u745e\u8fbe\u65b0\u4ea7\u54c1\u7684\u7814\u53d1\u65b9\u5411\u3002<\/p>\n
\u6b64\u6b21\u65b0\u52a0\u5165\u76844\u4f4d\u9876\u5c16\u4e13\u5bb6\uff0c\u5728\u5916\u5468\u4ecb\u5165\u9886\u57df\u5747\u6709\u7740\u6781\u4e3a\u4e30\u5bcc\u7684\u7ecf\u9a8c\u53ca\u524d\u6cbf\u7684\u6d1e\u89c1\uff0c\u4ed6\u4eec\u7684\u52a0\u5165\u8ba9\u5148\u745e\u8fbe\u6210\u4e3a\u5168\u7403\u6781\u5c11\u6570\u62e5\u6709\u5982\u6b64\u5e9e\u5927\u3001\u9ad8\u89c4\u683c\u4e13\u5bb6\u59d4\u5458\u4f1a\u7684\u5916\u5468\u4ecb\u5165\u4f01\u4e1a\u3002<\/p>\n
Peter Schneider\u535a\u58eb\u662f\u65e7\u91d1\u5c71\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u8840\u7ba1\u53ca\u8840\u7ba1\u8154\u5916\u79d1\u7cfb\u7684\u5916\u79d1\u6559\u6388\uff0c\u5728\u8fc7\u53bb\u768425\u5e74\u65f6\u95f4\u91cc\u4e00\u76f4\u81f4\u529b\u4e8e\u8840\u7ba1\u75be\u75c5\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u66fe\u5728\u7f8e\u56fd\u8840\u7ba1\u5916\u79d1\u534f\u4f1a\u7684\u591a\u4e2a\u59d4\u5458\u4f1a\u4efb\u804c\uff0c\u5e76\u62c5\u4efb\u591a\u9879\u4e34\u5e8a\u8bd5\u9a8c\u7684PI\uff0c\u4ea6\u66fe\u4efb\u7f8e\u56fd\u7f8e\u6566\u529bIN.PACTDCB\uff08\u836f\u7269\u6d82\u5c42\u7403\u56ca\uff09PI\u3002<\/p>\n
\u64c5\u957f\u4e8e\u8840\u7ba1\u5916\u79d1\u6cbb\u7597\u7684Matthew T. Menard\u535a\u58eb\u662f\u5e03\u83b1\u6839\u5987\u5973\u533b\u9662\u8840\u7ba1\u548c\u8840\u7ba1\u8154\u5956\u5b66\u91d1\u8ba1\u5212\u7684\u4e3b\u4efb\u53ca\u8840\u7ba1\u8154\u624b\u672f\u8ba1\u5212\u7684\u8054\u5e2d\u4e3b\u4efb\uff0c\u4e5f\u662f\u54c8\u4f5b\u533b\u5b66\u9662\u7684\u52a9\u7406\u5916\u79d1\u6559\u6388\uff0c\u4e5f\u662f\u9488\u5bf9\u91cd\u75c7\u80a2\u4f53\u7f3a\u8840\u60a3\u8005\u7684\u6700\u4f73\u8840\u7ba1\u8154\u6cbb\u7597\u4e0e\u6700\u4f73\u624b\u672f\u6cbb\u7597\uff08BEST-CLI\uff09\u7684PI\u3002<\/p>\n
Sahil A. Parikh\u535a\u58eb\u957f\u671f\u4e13\u6ce8\u4e8e\u52a8\u8109\u7ca5\u6837\u786c\u5316\u8840\u7ba1\u75be\u75c5\u53ca\u6574\u4e2a\u8840\u7ba1\u75be\u75c5\u7684\u4ecb\u5165\u6cbb\u7597\u3002\u4ed6\u662f\u591a\u9879\u4e34\u5e8a\u8bd5\u9a8c\u7684PI\uff0c\u5e76\u8054\u540c\u5fc3\u8840\u7ba1\u7814\u7a76\u57fa\u91d1\u4f1a\u3001\u7f8e\u56fd\u5fc3\u810f\u75c5\u5b66\u4f1a\u53ca\u5fc3\u8840\u7ba1\u9020\u5f71\u548c\u4ecb\u5165\u5b66\u4f1a\uff0c\u4e3a\u591a\u9879\u56fd\u5bb6\u533b\u751f\u57f9\u8bad\u53ca\u6301\u7eed\u533b\u5b66\u6559\u80b2\u8ba1\u5212\u63d0\u4f9b\u6307\u5bfc\u3002<\/p>\n
\u5fb7\u56fd\u8457\u540d\u8840\u7ba1\u4ecb\u5165\u4e13\u5bb6Thomas Zeller\u6559\u6388\u4e3a\u5fb7\u56fdUniversity Heart Center Freiburg\/Bad Krozingen\u8840\u7ba1\u5b66\u7cfb\u4e3b\u4efb\uff0c\u5176\u957f\u671f\u4e13\u6ce8\u4e8e\u590d\u6742\u7684\u8840\u7ba1\u5185\u4ecb\u5165\u65b0\u6280\u672f\u53ca\u4ea7\u54c1\u7684\u5f00\u53d1\u548c\u6d4b\u8bd5\uff0c\u66fe\u62c5\u4efb\u591a\u9879DCB\u76f8\u5173\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7684PI\uff0c\u7279\u522b\u662f\u5728\u65e9\u671fDCB\u7684\u7597\u6548\u9a8c\u8bc1\u4e2d\u8d77\u5230\u4e86\u5960\u5b9a\u57fa\u7840\u3002<\/p>\n
\u968f\u7740\u4e13\u5bb6\u4eec\u7684\u52a0\u5165\uff0c\u5148\u745e\u8fbe\u5728\u7f8e\u56fd\u7684AcoArt BTK \u6ce8\u518c\u4e34\u5e8a\uff08AcoArt BTK Global IDE Study\uff09\u4e5f\u8fdb\u5165\u52a0\u901f\u671f\u3002Matthew T. Menard\u535a\u58eb\u3001Sahil A. Parikh\u535a\u58eb\u53caThomas Zeller\u6559\u6388\u5c06\u4f5c\u4e3a\u8054\u5408\u9996\u5e2d\u7814\u7a76\u5458\u9886\u5bfc\u8be5\u7814\u7a76\u7684\u5feb\u901f\u63a8\u8fdb\u3002\u76ee\u524d\uff0c\u5148\u745e\u8fbeBTK\u4ea7\u54c1\u6709\u671b\u6210\u4e3a\u7f8e\u56fd\u4e43\u81f3\u5168\u7403\u9996\u4e2a\u83b7\u6279\u4e0a\u5e02\u7684\u4ea7\u54c1\uff0c\u5148\u745e\u8fbe\u4e5f\u6709\u671b\u6210\u4e3a\u4e2d\u56fd\u9996\u4e2a\u5c06\u5916\u5468\u4ecb\u5165\u4ea7\u54c1\u51fa\u53e3\u5230\u7f8e\u56fd\u7684\u4f01\u4e1a\u3002<\/p>\n
\u6b64\u524d\uff0c\u5148\u745e\u8fbeBTK\u4ea7\u54c1AcoArt Tulip™<\/sup>& Litos™<\/sup>\u5df2\u4e8e2019\u5e74\u83b7\u5f97\u7f8e\u56fdFDA\u6388\u4e88\u7684\u201c\u7a81\u7834\u6027\u5668\u68b0\u201d\u8ba4\u8bc1\uff0c\u8fd9\u4e5f\u662f\u9996\u6b3e\u83b7\u5f97\u8be5\u8ba4\u8bc1\u7684\u56fd\u4ea7\u5668\u68b0\u3002\u83b7\u5f97\u8be5\u8ba4\u5b9a\u610f\u5473\u7740\u4ea7\u54c1\u5c06\u5728\u7f8e\u56fd\u83b7\u5f97\u5feb\u901f\u5ba1\u6279\uff0c\u540c\u65f6\u4e00\u65e6\u83b7\u6279\u5219\u5373\u523b\u88ab\u7eb3\u5165\u7f8e\u56fd\u533b\u4fdd\u3002<\/p>\n \u5148\u745e\u8fbe\u8054\u5408\u521b\u59cb\u4eba\u53ca\u9996\u5e2d\u6267\u884c\u5b98\u674e\u9759\u8868\u793a\uff0c\u201c\u80fd\u5f97\u5230\u56db\u4f4d\u884c\u4e1a\u9876\u7ea7\u4e13\u5bb6\u8ba4\u53ef\u6211\u611f\u5230\u975e\u5e38\u8363\u5e78\uff0c\u5e76\u5bf9\u4ed6\u4eec\u7684\u52a0\u5165\u8868\u793a\u8bda\u631a\u7684\u6b22\u8fce\u3002\u5148\u745e\u8fbe\u521b\u7acb\u4e4b\u521d\u5c31\u4ee5\u89e3\u51b3\u533b\u751f\u548c\u60a3\u8005\u7684\u4e34\u5e8a\u75db\u70b9\u4e3a\u5df1\u4efb\uff0c\u5df2\u5f00\u53d1\u5e76\u83b7\u6279\u4e86\u591a\u6b3e\u2018First-in-class\u2019\u53ca\u2018Best-in-class\u2019\u4ea7\u54c1\uff0c\u4e3a\u6570\u4e07\u540d\u60a3\u8005\u89e3\u51b3\u4e86\u5916\u5468\u95ee\u9898\uff0c\u63d0\u5347\u4e86\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u3002\u968f\u7740\u4e13\u5bb6\u4eec\u7684\u52a0\u5165\uff0c\u6211\u76f8\u4fe1\u5148\u745e\u8fbe\u5c06\u7ee7\u7eed\u4fdd\u6301\u5148\u53d1\u4f18\u52bf\uff0c\u4e0d\u4ec5\u5728\u4ea7\u54c1\u7684\u5f00\u53d1\u4e0a\u6709\u66f4\u4e3a\u5353\u8d8a\u7684\u8fdb\u6b65\uff0c\u540c\u65f6\uff0c\u5728\u4ea7\u54c1\u9002\u5e94\u75c7\u7684\u6269\u5145\u53ca\u6d77\u5916\u6ce8\u518c\u83b7\u6279\u4e0a\u4e5f\u5c06\u6301\u7eed\u52a0\u901f\u3002\u201d<\/p>\n \u6b64\u524d\uff0c\u5148\u745e\u8fbeDCB\u4ea7\u54c1\u5df2\u5728\u5168\u740312\u4e2a\u56fd\u5bb6\u83b7\u6279\uff0c\u5305\u62ec\u533b\u5b66\u6280\u672f\u6781\u4e3a\u5148\u8fdb\u7684\u5fb7\u56fd\u3001\u610f\u5927\u5229\u3001\u745e\u58eb\u3001\u897f\u73ed\u7259\u7b49\u3002\u6b64\u6b21BTK\u4ea7\u54c1\u5728\u7f8e\u56fd\u7684\u6ce8\u518c\u5c06\u6807\u5fd7\u7740\u5148\u745e\u8fbe\u5c06\u5411\u5168\u7403\u6700\u4e25\u82db\u7684\u5ba1\u6279\u7cfb\u7edf\u53d1\u8d77\u51b2\u51fb\uff0c\u5f70\u663e\u51fa\u5bf9\u6280\u672f\u53ca\u4ea7\u54c1\u5145\u8db3\u7684\u4fe1\u5fc3\u3002\u622a\u81f3<\/span>\u76ee\u524d\uff0c\u5728\u5916\u5468\u5668\u68b0\u4ecb\u5165\u9886\u57df\u4e2d\uff0c\u7f8e\u56fd\u5c1a\u672a\u6709BTK DCB\u4ea7\u54c1\u83b7\u6279\uff0c\u6240\u4ee5\u4ea7\u54c1\u4e00\u65e6\u83b7\u6279\uff0c\u6709\u671b\u6210\u4e3a\u4e34\u5e8a\u7684\u552f\u4e00\u9009\u62e9\u3002\u636e\u5f17\u82e5\u65af\u7279\u6c99\u5229\u6587\u62a5\u544a\u663e\u793a\uff0c2019\u5e74\u7f8e\u56fd\u4e0b\u80a2\u52a8\u8109\u4ecb\u5165\u624b\u672f\u9ad8\u8fbe50\u4e07\u53f0\uff0c\u5176\u4e2d\u819d\u4e0b\u624b\u672f\u8fd120\u4e07\u53f0\u3002\u800c\u73b0\u6709\u7597\u6cd5\u4ecd\u4e3a\u666e\u901a\u7403\u56ca\u3002\u4f34\u968f\u7cd6\u5c3f\u75c5\u53ca\u9ad8\u8840\u538b\u7684\u9ad8\u53d1\u4f7f\u5176\u589e\u957f\u7387\u4e0d\u65ad\u6500\u5347\uff0c\u5e02\u573a\u89c4\u6a21\u5bb9\u91cf\u5c06\u6301\u7eed\u589e\u5927\uff0c\u836f\u7269\u7403\u56ca\u7528\u4e8e\u819d\u4e0b\u5728\u7f8e\u56fd\u5e02\u573a\u6781\u5177\u6f5c\u529b\u3002<\/p>\n","protected":false},"excerpt":{"rendered":" \u5317\u4eac2021\u5e7410\u670813\u65e5 \/\u7f8e\u901a\u793e\/ — \u8fd1\u65e5\uff0c\u5148\u745e\u8fbe\u79d1\u5b66\u987e\u95ee\u59d4\u5458\u4f1a\u518d\u8fce4\u4f4d\u5168\u7403\u9876\u5c16\u533b\u7597\u4e13\u5bb6\u52a0\u5165\uff0c\u5176\u4e2d3\u4f4d\u4f1a\u62c5\u4efb\u5148\u745e\u8fbeAcoArt\u819d\u4e0b\u836f\u7269\u6d82\u5c42\u7403\u56ca\uff08BTK\uff09\u7f8e\u56fd\u6ce8\u518c\u4e34\u5e8aPI\u3002\u65b0\u52a0\u5165\u7684\u4e13\u5bb6\u5305\u62ecPeter Schneider\u6559\u6388\u3001Matthew T. Menard\u535a\u58eb\u3001Sahil A. Parikh\u535a\u58eb\u53caThomas Zeller\u6559\u6388\uff0c4\u4f4d\u4e13\u5bb6\u5c06\u6307\u5bfc\u5148\u745e\u8fbe\u7684\u6838\u5fc3\u4ea7\u54c1\u5728\u7f8e\u56fd\u548c\u6b27\u6d32\u7b49\u5730\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u5e76\u5728\u540e\u671f\u7684\u4ea7\u54c1\u6ce8\u518c\u83b7\u6279\u4e2d\u63d0\u4f9b\u5e2e\u52a9\uff0c\u52a0\u901f\u5916\u5468\u4ecb\u5165\u521b\u65b0\u4ea7\u54c1\u7684\u4e34\u5e8a\u843d\u5730\u3002\u540c\u65f6\uff0c\u4ed6\u4eec\u5c06\u51ed\u501f\u81ea\u8eab\u5728\u5916\u5468\u4ecb\u5165\u9886\u57df\u7684\u4e13\u4e1a\u6743\u5a01\uff0c\u6307\u5bfc\u5148\u745e\u8fbe\u65b0\u4ea7\u54c1\u7684\u7814\u53d1\u65b9\u5411\u3002 \u6b64\u6b21\u65b0\u52a0\u5165\u76844\u4f4d\u9876\u5c16\u4e13\u5bb6\uff0c\u5728\u5916\u5468\u4ecb\u5165\u9886\u57df\u5747\u6709\u7740\u6781\u4e3a\u4e30\u5bcc\u7684\u7ecf\u9a8c\u53ca\u524d\u6cbf\u7684\u6d1e\u89c1\uff0c\u4ed6\u4eec\u7684\u52a0\u5165\u8ba9\u5148\u745e\u8fbe\u6210\u4e3a\u5168\u7403\u6781\u5c11\u6570\u62e5\u6709\u5982\u6b64\u5e9e\u5927\u3001\u9ad8\u89c4\u683c\u4e13\u5bb6\u59d4\u5458\u4f1a\u7684\u5916\u5468\u4ecb\u5165\u4f01\u4e1a\u3002 Peter Schneider\u535a\u58eb\u662f\u65e7\u91d1\u5c71\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u8840\u7ba1\u53ca\u8840\u7ba1\u8154\u5916\u79d1\u7cfb\u7684\u5916\u79d1\u6559\u6388\uff0c\u5728\u8fc7\u53bb\u768425\u5e74\u65f6\u95f4\u91cc\u4e00\u76f4\u81f4\u529b\u4e8e\u8840\u7ba1\u75be\u75c5\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u66fe\u5728\u7f8e\u56fd\u8840\u7ba1\u5916\u79d1\u534f\u4f1a\u7684\u591a\u4e2a\u59d4\u5458\u4f1a\u4efb\u804c\uff0c\u5e76\u62c5\u4efb\u591a\u9879\u4e34\u5e8a\u8bd5\u9a8c\u7684PI\uff0c\u4ea6\u66fe\u4efb\u7f8e\u56fd\u7f8e\u6566\u529bIN.PACTDCB\uff08\u836f\u7269\u6d82\u5c42\u7403\u56ca\uff09PI\u3002 \u64c5\u957f\u4e8e\u8840\u7ba1\u5916\u79d1\u6cbb\u7597\u7684Matthew T. Menard\u535a\u58eb\u662f\u5e03\u83b1\u6839\u5987\u5973\u533b\u9662\u8840\u7ba1\u548c\u8840\u7ba1\u8154\u5956\u5b66\u91d1\u8ba1\u5212\u7684\u4e3b\u4efb\u53ca\u8840\u7ba1\u8154\u624b\u672f\u8ba1\u5212\u7684\u8054\u5e2d\u4e3b\u4efb\uff0c\u4e5f\u662f\u54c8\u4f5b\u533b\u5b66\u9662\u7684\u52a9\u7406\u5916\u79d1\u6559\u6388\uff0c\u4e5f\u662f\u9488\u5bf9\u91cd\u75c7\u80a2\u4f53\u7f3a\u8840\u60a3\u8005\u7684\u6700\u4f73\u8840\u7ba1\u8154\u6cbb\u7597\u4e0e\u6700\u4f73\u624b\u672f\u6cbb\u7597\uff08BEST-CLI\uff09\u7684PI\u3002 Sahil A. Parikh\u535a\u58eb\u957f\u671f\u4e13\u6ce8\u4e8e\u52a8\u8109\u7ca5\u6837\u786c\u5316\u8840\u7ba1\u75be\u75c5\u53ca\u6574\u4e2a\u8840\u7ba1\u75be\u75c5\u7684\u4ecb\u5165\u6cbb\u7597\u3002\u4ed6\u662f\u591a\u9879\u4e34\u5e8a\u8bd5\u9a8c\u7684PI\uff0c\u5e76\u8054\u540c\u5fc3\u8840\u7ba1\u7814\u7a76\u57fa\u91d1\u4f1a\u3001\u7f8e\u56fd\u5fc3\u810f\u75c5\u5b66\u4f1a\u53ca\u5fc3\u8840\u7ba1\u9020\u5f71\u548c\u4ecb\u5165\u5b66\u4f1a\uff0c\u4e3a\u591a\u9879\u56fd\u5bb6\u533b\u751f\u57f9\u8bad\u53ca\u6301\u7eed\u533b\u5b66\u6559\u80b2\u8ba1\u5212\u63d0\u4f9b\u6307\u5bfc\u3002 \u5fb7\u56fd\u8457\u540d\u8840\u7ba1\u4ecb\u5165\u4e13\u5bb6Thomas Zeller\u6559\u6388\u4e3a\u5fb7\u56fdUniversity Heart Center Freiburg\/Bad Krozingen\u8840\u7ba1\u5b66\u7cfb\u4e3b\u4efb\uff0c\u5176\u957f\u671f\u4e13\u6ce8\u4e8e\u590d\u6742\u7684\u8840\u7ba1\u5185\u4ecb\u5165\u65b0\u6280\u672f\u53ca\u4ea7\u54c1\u7684\u5f00\u53d1\u548c\u6d4b\u8bd5\uff0c\u66fe\u62c5\u4efb\u591a\u9879DCB\u76f8\u5173\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7684PI\uff0c\u7279\u522b\u662f\u5728\u65e9\u671fDCB\u7684\u7597\u6548\u9a8c\u8bc1\u4e2d\u8d77\u5230\u4e86\u5960\u5b9a\u57fa\u7840\u3002 \u968f\u7740\u4e13\u5bb6\u4eec\u7684\u52a0\u5165\uff0c\u5148\u745e\u8fbe\u5728\u7f8e\u56fd\u7684AcoArt BTK \u6ce8\u518c\u4e34\u5e8a\uff08AcoArt BTK Global IDE Study\uff09\u4e5f\u8fdb\u5165\u52a0\u901f\u671f\u3002Matthew T. 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