{"id":46585,"date":"2021-09-30T13:06:00","date_gmt":"2021-09-30T06:06:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021093013060046585"},"modified":"2021-09-30T17:56:53","modified_gmt":"2021-09-30T09:56:53","slug":"%e5%8d%a1%e7%91%9e%e5%88%a9%e7%8f%a0%e5%8d%95%e6%8a%97%e6%96%b0%e8%be%85%e5%8a%a9%e6%b2%bb%e7%96%97%e5%b1%80%e9%83%a8%e6%99%9a%e6%9c%9f%e9%a3%9f%e7%ae%a1%e9%b3%9e%e7%99%8c%e7%a0%94%e7%a9%b6%e6%88%90","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021093013060046585","title":{"rendered":"\u5361\u745e\u5229\u73e0\u5355\u6297\u65b0\u8f85\u52a9\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u98df\u7ba1\u9cde\u764c\u7814\u7a76\u6210\u679c\u4eae\u76f8\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u5b66\u672f\u5e74\u4f1a"},"content":{"rendered":"

\u4e0a\u6d772021\u5e749\u670830\u65e5 \/\u7f8e\u901a\u793e\/ — 9\u670829\u65e5\uff0c\u7b2c\u4e8c\u5341\u56db\u5c4a\u5168\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u5927\u4f1a\u66a82021\u5e74CSCO\u5b66\u672f\u5e74\u4f1a\u4e0a\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u8054\u5408\u7d2b\u6749\u9187\u548c\u5948\u8fbe\u94c2\u65b0\u8f85\u52a9\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u98df\u7ba1\u9cde\u764c\u7684\u5355\u81c2\u3001\u5f00\u653e\u3001<\/b>II<\/b>\u671f\u63a2\u7d22\u6027\u7814\u7a76<\/b>\uff08ESPRIT\u7814\u7a76\uff09\u7684\u9636\u6bb5\u6027\u7814\u7a76\u7ed3\u679c<\/b>\u4ece1470\u7bc7\u6295\u7a3f\u8bba\u6587\u4e2d\u8131\u9896\u800c\u51fa\uff0c\u88ab\u7eb3\u5165\u5927\u4f1a\u53e3\u5934\u62a5\u544a\u3002\u4f5c\u4e3a\u8be5\u9879\u7814\u7a76\u7684\u4e3b\u8981\u7814\u7a76\u8005\uff0c\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u4e3b\u4efb\u533b\u5e08\u9a6c\u5efa\u7fa4\u6559\u6388\u4ee3\u8868\u7814\u7a76\u56e2\u961f\u5728\u5927\u4f1a\u4e0a\u4f5c\u4e86\u53e3\u5934\u62a5\u544a\u3002<\/p>\n

\n

\"\"<\/a>
<\/span><\/p>\n<\/p><\/div>\n

\u98df\u7ba1\u764c\u662f\u5177\u6709\u201c\u4e2d\u56fd\u7279\u8272\u201d\u7684\u80bf\u7624\uff0c\u6bcf\u5e74\u65b0\u53d1\u548c\u6b7b\u4ea1\u75c5\u4f8b\u5747\u5360\u5168\u7403\u75c5\u4f8b\u7684\u4e00\u534a\u4ee5\u4e0a[1]<\/sup>\u3002\u65e9\u671f\u98df\u7ba1\u764c\u75c7\u72b6\u5e38\u4e0d\u660e\u663e\uff0c\u8fd175%\u7684\u60a3\u8005\u786e\u8bca\u65f6\u5df2\u8fdb\u5c55\u4e3a\u665a\u671f\u6216\u4f34\u6709\u8fdc\u5904\u8f6c\u79fb\u3002\u5bf9\u4e8e\u5c40\u90e8\u665a\u671f\u53ef\u5207\u9664\u7684\u98df\u7ba1\u764c\uff0c\u5355\u7eaf\u624b\u672f\u6cbb\u7597\u60a3\u8005\u9884\u540e\u8f83\u5dee\uff0c5\u5e74\u751f\u5b58\u7387\u4f4e\u81f314% [2,3] <\/sup>\uff0c\u624b\u672f\u5207\u9664\u540e\u60a3\u8005\u590d\u53d1\u7387\u9ad8\u8fbe16%-47%[4]<\/sup>\u3002\u591a\u9879\u7814\u7a76\u53d1\u73b0\uff0c\u65b0\u8f85\u52a9\u6cbb\u7597\u53ef\u5ef6\u957f\u60a3\u8005\u751f\u5b58\u3002\u76ee\u524d\uff0c\u201c\u65b0\u8f85\u52a9\u653e\u5316\u7597+\u624b\u672f\u201d \u7684\u6cbb\u7597\u6a21\u5f0f\u662f\u88ab\u5e7f\u6cdb\u63a5\u53d7\u7684\u6807\u51c6\u6cbb\u7597\u3002\u4f46\u201c\u65b0\u8f85\u52a9\u653e\u5316\u7597+\u624b\u672f\u201d\u7684\u5e94\u7528\u4ecd\u5b58\u5728\u5c40\u9650\u6027\uff0c\u5373\u4f7f\u60a3\u8005\u63a5\u53d7\u65b0\u8f85\u52a9\u653e\u5316\u7597\uff0c\u672f\u540e\u4ecd\u6709\u8f83\u9ad8\u7684\u590d\u53d1\u7387\u548c\u8fdc\u5904\u8f6c\u79fb\u7387\u3002\u6b64\u5916\uff0c\u653e\u5316\u7597\u7684\u4e0d\u826f\u53cd\u5e94\u7684\u6bd2\u6027\u53e0\u52a0\uff0c\u53ef\u80fd\u5bfc\u81f4\u60a3\u8005\u6b7b\u4ea1\u7387\u589e\u52a0\u3002\u56e0\u6b64\uff0c\u5c40\u90e8\u665a\u671f\u98df\u7ba1\u764c\u60a3\u8005\u65b0\u8f85\u52a9\u6cbb\u7597\u4e9f\u9700\u4e00\u79cd\u66f4\u4e3a\u5b89\u5168\u6709\u6548\u7684\u6cbb\u7597\u6a21\u5f0f\u3002 <\/p>\n

ESPRIT\u7814\u7a76\u7684\u9636\u6bb5\u6027\u6570\u636e\u663e\u793a\uff0c\u5bf9\u4e8e\u5c40\u90e8\u665a\u671f\u53ef\u5207\u9664\u7684\u98df\u7ba1\u764c\u60a3\u8005\uff0c\u201c\u65b0\u8f85\u52a9\u514d\u75ab\u8054\u5408\u5316\u7597\u201d \u7684\u6cbb\u7597\u6a21\u5f0f\u80fd\u4e3a\u60a3\u8005\u5e26\u6765\u826f\u597d\u7684\u75be\u75c5\u7f13\u89e3\uff0c\u5ba2\u89c2\u7f13\u89e3\u7387\u8fbe\u523050%\uff0c\u7ea656%\u7684\u60a3\u8005\u5728\u5b8c\u6210\u65b0\u8f85\u52a9\u6cbb\u7597\u540e\u80fd\u591f\u5b9e\u73b0\u964d\u671f\u3002\u572813\u4f8b\u624b\u672f\u60a3\u8005\u4e2d\uff0c\u6240\u6709\u60a3\u8005\u5747\u5b9e\u73b0\u4e86\u5b8c\u5168\u624b\u672f\u5207\u9664\uff0c\u75c5\u7406\u5b8c\u5168\u7f13\u89e3\u7387\u8fbe\u523038.46%\uff0c\u4e3b\u8981\u75c5\u7406\u7f13\u89e3\u7387\u8fbe\u523061.5%\u3002\u540c\u65f6\uff0c\u8fd9\u9879\u7814\u7a76\u4e5f\u53d1\u73b0\uff0c \u201c\u65b0\u8f85\u52a9\u514d\u75ab\u8054\u5408\u5316\u7597\u201d \u7684\u6cbb\u7597\u6a21\u5f0f\u5177\u6709\u826f\u597d\u8010\u53d7\u6027\uff0c\u65b0\u8f85\u52a9\u514d\u75ab\u8054\u5408\u5316\u7597\u4e0d\u4f1a\u589e\u52a0\u60a3\u8005\u7684\u624b\u672f\u96be\u5ea6\u3002<\/p>\n

\u9a6c\u5efa\u7fa4\u6559\u6388\u5728\u53e3\u5934\u62a5\u544a\u4e2d\u6307\u51fa\uff1a\u201cESPRIT\u7814\u7a76\u7684\u7ed3\u679c\u63d0\u793a\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u8054\u5408\u7d2b\u6749\u9187\u548c\u5948\u8fbe\u94c2\u65b0\u8f85\u52a9\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u98df\u7ba1\u9cde\u764c\uff0c\u80fd\u591f\u5b9e\u73b0\u80bf\u7624\u7f29\u5c0f\u5e76\u5b8c\u6210\u964d\u671f\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u826f\u597d\u7684\u75be\u75c5\u7f13\u89e3\u3002\u76ee\u524d\uff0c\u8fd9\u9879\u7814\u7a76\u4ecd\u5728\u6301\u7eed\u62db\u52df\u60a3\u8005\u4e2d\u3002\u6211\u4eec\u4e5f\u671f\u5f85\u8fd9\u9879\u7814\u7a76\u7684\u7ec8\u671f\u7ed3\u679c\u7684\u516c\u5e03\u80fd\u591f\u4e3a\u98df\u7ba1\u764c\u65b0\u8f85\u52a9\u6cbb\u7597\u63d0\u4f9b\u4e00\u79cd\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002\u201d<\/p>\n

\u8be5\u9879\u524d\u6cbf\u7814\u7a76\u5bf9\u4e8e\u5ef6\u957f\u60a3\u8005\u751f\u5b58\u65f6\u95f4\uff0c\u6539\u5584\u60a3\u8005\u9884\u540e\u610f\u4e49\u91cd\u5927\u3002\u636e\u6089\uff0c\u7531\u9a6c\u5efa\u7fa4\u6559\u6388\u56e2\u961f\u53d1\u8d77\u7684ESPRIT\u7814\u7a76\u7684\u7814\u7a76\u6458\u8981\u5df2\u57282021\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\u5728\u7ebf\u53d1\u8868\uff0c\u5176\u7814\u7a76\u8bbe\u8ba1\u53ca\u9636\u6bb5\u6027\u7ed3\u679c\u5df2\u83b7\u5f97\u56fd\u9645\u5b66\u672f\u754c\u5173\u6ce8\u4e0e\u8ba4\u53ef\u3002<\/p>\n

\u5361\u745e\u5229\u73e0\u5355\u6297\u7531\u6c5f\u82cf\u6052\u745e\u533b\u836f\u80a1\u4efd\u6709\u9650\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\uff0c\u662f\u4e00\u79cd\u4eba\u7c7b\u514d\u75ab\u7403\u86cb\u767dG4\uff08IgG4\uff09\u5355\u514b\u9686\u6297\u4f53\u3002\u76ee\u524d\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u5728\u4e2d\u56fd\u5df2\u83b7\u6279\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u3001\u809d\u764c\u3001\u80ba\u764c\u3001\u98df\u7ba1\u764c\u3001\u9f3b\u54bd\u764c\u7b496\u5927\u9002\u5e94\u75c7\uff0c\u4e14\u665a\u671f\u80ba\u764c\u3001\u809d\u764c\u3001\u98df\u7ba1\u764c\u548c\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u8fd94\u4e2a\u9002\u5e94\u75c7\u5df2\u88ab\u7eb3\u5165\u65b0\u7248\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\u3002\u9664\u65b0\u8f85\u52a9\u6cbb\u7597\u4ee5\u5916\uff0cESCORT-1st\u7814\u7a76\u4e5f\u8bc1\u5b9e\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u8054\u5408\u7d2b\u6749\u9187\u548c\u987a\u94c2\u4e00\u7ebf\u6cbb\u7597\u665a\u671f\u98df\u7ba1\u9cde\u764c\u60a3\u8005\u5177\u6709\u663e\u8457\u83b7\u76ca\uff0c\u5ba2\u89c2\u7f13\u89e3\u7387\u8fbe72.1%\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u8fbe15.3\u4e2a\u6708\u3002\u8be5\u7a81\u7834\u6027\u7814\u7a76\u6210\u679c\u5df2\u5168\u6587\u5728\u7ebf\u53d1\u8868\u4e8e\u56fd\u9645\u9876\u5c16\u533b\u5b66\u671f\u520a\u300a\u7f8e\u56fd\u533b\u5b66\u4f1a\u6742\u5fd7\u300b\uff08JAMA\u4e3b\u520a\uff09[5]<\/sup>\u3002<\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/p>\n

\n\n\n\n\n\n\n\n
\n

[1]. Chen W, et al. Cancer statistics in China, 2015[J]. CA Cancer J Clin, 2016, 66(2): 115-132.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[2]. Reeh M, Nentwich MF, Asani S, et al. Locally advanced esophageal carcinoma: is there still a role of surgery alone without neoadjuvant treatment?[J]. Journal of Gastrointestinal Surgery, 2015, 19(4): 587-593.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[3]. Yu S, Zhang W, Ni W, et al. A propensity-score matching analysis comparing long-term survival of surgery alone and postoperative treatment for patients in node positive or stage III esophageal squamous cell carcinoma after R0 esophagectomy[J]. Radiotherapy and Oncology, 2019, 140: 159-166.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[4]. Jung HK, Tae CH, Lee HA, et al. Treatment pattern and overall survival in esophageal cancer during a 13-year period: A nationwide cohort study of 6,354 Korean patients[J]. PloS One, 2020, 15(4): e0231456.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[5]. Luo H, Lu J, Bai Y, et al. Effect of camrelizumab vs placebo added to chemotherapy on survival and progression-free survival in patients with advanced or metastatic esophageal squamous cell carcinoma: the ESCORT-1st randomized clinical trial[J]. JAMA, 2021, 326(10): 916-925.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n

 <\/p>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

\u4e0a\u6d772021\u5e749\u670830\u65e5 \/\u7f8e\u901a\u793e\/ — 9\u670829\u65e5\uff0c\u7b2c\u4e8c\u5341\u56db\u5c4a\u5168\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u5927\u4f1a\u66a82021\u5e74CSCO\u5b66\u672f\u5e74\u4f1a\u4e0a\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u8054\u5408\u7d2b\u6749\u9187\u548c\u5948\u8fbe\u94c2\u65b0\u8f85\u52a9\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u98df\u7ba1\u9cde\u764c\u7684\u5355\u81c2\u3001\u5f00\u653e\u3001II\u671f\u63a2\u7d22\u6027\u7814\u7a76\uff08ESPRIT\u7814\u7a76\uff09\u7684\u9636\u6bb5\u6027\u7814\u7a76\u7ed3\u679c\u4ece1470\u7bc7\u6295\u7a3f\u8bba\u6587\u4e2d\u8131\u9896\u800c\u51fa\uff0c\u88ab\u7eb3\u5165\u5927\u4f1a\u53e3\u5934\u62a5\u544a\u3002\u4f5c\u4e3a\u8be5\u9879\u7814\u7a76\u7684\u4e3b\u8981\u7814\u7a76\u8005\uff0c\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u4e3b\u4efb\u533b\u5e08\u9a6c\u5efa\u7fa4\u6559\u6388\u4ee3\u8868\u7814\u7a76\u56e2\u961f\u5728\u5927\u4f1a\u4e0a\u4f5c\u4e86\u53e3\u5934\u62a5\u544a\u3002 \u98df\u7ba1\u764c\u662f\u5177\u6709\u201c\u4e2d\u56fd\u7279\u8272\u201d\u7684\u80bf\u7624\uff0c\u6bcf\u5e74\u65b0\u53d1\u548c\u6b7b\u4ea1\u75c5\u4f8b\u5747\u5360\u5168\u7403\u75c5\u4f8b\u7684\u4e00\u534a\u4ee5\u4e0a[1]\u3002\u65e9\u671f\u98df\u7ba1\u764c\u75c7\u72b6\u5e38\u4e0d\u660e\u663e\uff0c\u8fd175%\u7684\u60a3\u8005\u786e\u8bca\u65f6\u5df2\u8fdb\u5c55\u4e3a\u665a\u671f\u6216\u4f34\u6709\u8fdc\u5904\u8f6c\u79fb\u3002\u5bf9\u4e8e\u5c40\u90e8\u665a\u671f\u53ef\u5207\u9664\u7684\u98df\u7ba1\u764c\uff0c\u5355\u7eaf\u624b\u672f\u6cbb\u7597\u60a3\u8005\u9884\u540e\u8f83\u5dee\uff0c5\u5e74\u751f\u5b58\u7387\u4f4e\u81f314% [2,3] \uff0c\u624b\u672f\u5207\u9664\u540e\u60a3\u8005\u590d\u53d1\u7387\u9ad8\u8fbe16%-47%[4]\u3002\u591a\u9879\u7814\u7a76\u53d1\u73b0\uff0c\u65b0\u8f85\u52a9\u6cbb\u7597\u53ef\u5ef6\u957f\u60a3\u8005\u751f\u5b58\u3002\u76ee\u524d\uff0c\u201c\u65b0\u8f85\u52a9\u653e\u5316\u7597+\u624b\u672f\u201d \u7684\u6cbb\u7597\u6a21\u5f0f\u662f\u88ab\u5e7f\u6cdb\u63a5\u53d7\u7684\u6807\u51c6\u6cbb\u7597\u3002\u4f46\u201c\u65b0\u8f85\u52a9\u653e\u5316\u7597+\u624b\u672f\u201d\u7684\u5e94\u7528\u4ecd\u5b58\u5728\u5c40\u9650\u6027\uff0c\u5373\u4f7f\u60a3\u8005\u63a5\u53d7\u65b0\u8f85\u52a9\u653e\u5316\u7597\uff0c\u672f\u540e\u4ecd\u6709\u8f83\u9ad8\u7684\u590d\u53d1\u7387\u548c\u8fdc\u5904\u8f6c\u79fb\u7387\u3002\u6b64\u5916\uff0c\u653e\u5316\u7597\u7684\u4e0d\u826f\u53cd\u5e94\u7684\u6bd2\u6027\u53e0\u52a0\uff0c\u53ef\u80fd\u5bfc\u81f4\u60a3\u8005\u6b7b\u4ea1\u7387\u589e\u52a0\u3002\u56e0\u6b64\uff0c\u5c40\u90e8\u665a\u671f\u98df\u7ba1\u764c\u60a3\u8005\u65b0\u8f85\u52a9\u6cbb\u7597\u4e9f\u9700\u4e00\u79cd\u66f4\u4e3a\u5b89\u5168\u6709\u6548\u7684\u6cbb\u7597\u6a21\u5f0f\u3002  ESPRIT\u7814\u7a76\u7684\u9636\u6bb5\u6027\u6570\u636e\u663e\u793a\uff0c\u5bf9\u4e8e\u5c40\u90e8\u665a\u671f\u53ef\u5207\u9664\u7684\u98df\u7ba1\u764c\u60a3\u8005\uff0c\u201c\u65b0\u8f85\u52a9\u514d\u75ab\u8054\u5408\u5316\u7597\u201d \u7684\u6cbb\u7597\u6a21\u5f0f\u80fd\u4e3a\u60a3\u8005\u5e26\u6765\u826f\u597d\u7684\u75be\u75c5\u7f13\u89e3\uff0c\u5ba2\u89c2\u7f13\u89e3\u7387\u8fbe\u523050%\uff0c\u7ea656%\u7684\u60a3\u8005\u5728\u5b8c\u6210\u65b0\u8f85\u52a9\u6cbb\u7597\u540e\u80fd\u591f\u5b9e\u73b0\u964d\u671f\u3002\u572813\u4f8b\u624b\u672f\u60a3\u8005\u4e2d\uff0c\u6240\u6709\u60a3\u8005\u5747\u5b9e\u73b0\u4e86\u5b8c\u5168\u624b\u672f\u5207\u9664\uff0c\u75c5\u7406\u5b8c\u5168\u7f13\u89e3\u7387\u8fbe\u523038.46%\uff0c\u4e3b\u8981\u75c5\u7406\u7f13\u89e3\u7387\u8fbe\u523061.5%\u3002\u540c\u65f6\uff0c\u8fd9\u9879\u7814\u7a76\u4e5f\u53d1\u73b0\uff0c \u201c\u65b0\u8f85\u52a9\u514d\u75ab\u8054\u5408\u5316\u7597\u201d \u7684\u6cbb\u7597\u6a21\u5f0f\u5177\u6709\u826f\u597d\u8010\u53d7\u6027\uff0c\u65b0\u8f85\u52a9\u514d\u75ab\u8054\u5408\u5316\u7597\u4e0d\u4f1a\u589e\u52a0\u60a3\u8005\u7684\u624b\u672f\u96be\u5ea6\u3002 \u9a6c\u5efa\u7fa4\u6559\u6388\u5728\u53e3\u5934\u62a5\u544a\u4e2d\u6307\u51fa\uff1a\u201cESPRIT\u7814\u7a76\u7684\u7ed3\u679c\u63d0\u793a\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u8054\u5408\u7d2b\u6749\u9187\u548c\u5948\u8fbe\u94c2\u65b0\u8f85\u52a9\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u98df\u7ba1\u9cde\u764c\uff0c\u80fd\u591f\u5b9e\u73b0\u80bf\u7624\u7f29\u5c0f\u5e76\u5b8c\u6210\u964d\u671f\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u826f\u597d\u7684\u75be\u75c5\u7f13\u89e3\u3002\u76ee\u524d\uff0c\u8fd9\u9879\u7814\u7a76\u4ecd\u5728\u6301\u7eed\u62db\u52df\u60a3\u8005\u4e2d\u3002\u6211\u4eec\u4e5f\u671f\u5f85\u8fd9\u9879\u7814\u7a76\u7684\u7ec8\u671f\u7ed3\u679c\u7684\u516c\u5e03\u80fd\u591f\u4e3a\u98df\u7ba1\u764c\u65b0\u8f85\u52a9\u6cbb\u7597\u63d0\u4f9b\u4e00\u79cd\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002\u201d \u8be5\u9879\u524d\u6cbf\u7814\u7a76\u5bf9\u4e8e\u5ef6\u957f\u60a3\u8005\u751f\u5b58\u65f6\u95f4\uff0c\u6539\u5584\u60a3\u8005\u9884\u540e\u610f\u4e49\u91cd\u5927\u3002\u636e\u6089\uff0c\u7531\u9a6c\u5efa\u7fa4\u6559\u6388\u56e2\u961f\u53d1\u8d77\u7684ESPRIT\u7814\u7a76\u7684\u7814\u7a76\u6458\u8981\u5df2\u57282021\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\u5728\u7ebf\u53d1\u8868\uff0c\u5176\u7814\u7a76\u8bbe\u8ba1\u53ca\u9636\u6bb5\u6027\u7ed3\u679c\u5df2\u83b7\u5f97\u56fd\u9645\u5b66\u672f\u754c\u5173\u6ce8\u4e0e\u8ba4\u53ef\u3002 \u5361\u745e\u5229\u73e0\u5355\u6297\u7531\u6c5f\u82cf\u6052\u745e\u533b\u836f\u80a1\u4efd\u6709\u9650\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\uff0c\u662f\u4e00\u79cd\u4eba\u7c7b\u514d\u75ab\u7403\u86cb\u767dG4\uff08IgG4\uff09\u5355\u514b\u9686\u6297\u4f53\u3002\u76ee\u524d\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u5728\u4e2d\u56fd\u5df2\u83b7\u6279\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u3001\u809d\u764c\u3001\u80ba\u764c\u3001\u98df\u7ba1\u764c\u3001\u9f3b\u54bd\u764c\u7b496\u5927\u9002\u5e94\u75c7\uff0c\u4e14\u665a\u671f\u80ba\u764c\u3001\u809d\u764c\u3001\u98df\u7ba1\u764c\u548c\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u8fd94\u4e2a\u9002\u5e94\u75c7\u5df2\u88ab\u7eb3\u5165\u65b0\u7248\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\u3002\u9664\u65b0\u8f85\u52a9\u6cbb\u7597\u4ee5\u5916\uff0cESCORT-1st\u7814\u7a76\u4e5f\u8bc1\u5b9e\uff0c\u5361\u745e\u5229\u73e0\u5355\u6297\u8054\u5408\u7d2b\u6749\u9187\u548c\u987a\u94c2\u4e00\u7ebf\u6cbb\u7597\u665a\u671f\u98df\u7ba1\u9cde\u764c\u60a3\u8005\u5177\u6709\u663e\u8457\u83b7\u76ca\uff0c\u5ba2\u89c2\u7f13\u89e3\u7387\u8fbe72.1%\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u8fbe15.3\u4e2a\u6708\u3002\u8be5\u7a81\u7834\u6027\u7814\u7a76\u6210\u679c\u5df2\u5168\u6587\u5728\u7ebf\u53d1\u8868\u4e8e\u56fd\u9645\u9876\u5c16\u533b\u5b66\u671f\u520a\u300a\u7f8e\u56fd\u533b\u5b66\u4f1a\u6742\u5fd7\u300b\uff08JAMA\u4e3b\u520a\uff09[5]\u3002 \u53c2\u8003\u6587\u732e\uff1a [1]. Chen W, et al. Cancer statistics in China, 2015[J]. CA Cancer J Clin, 2016, 66(2): 115-132. [2]. Reeh M, Nentwich MF, Asani S, et al. Locally advanced esophageal carcinoma: is there still a role of surgery alone without neoadjuvant treatment?[J]. Journal… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":46588,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-46585","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/46585","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=46585"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/46585\/revisions"}],"predecessor-version":[{"id":46587,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/46585\/revisions\/46587"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/46588"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=46585"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=46585"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=46585"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}