{"id":43653,"date":"2021-09-09T06:00:00","date_gmt":"2021-09-08T23:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021090906000043653"},"modified":"2021-09-09T21:39:23","modified_gmt":"2021-09-09T13:39:23","slug":"redhill%e6%8a%a5%e5%91%8amovantik%e6%95%b0%e6%8d%ae%e5%88%86%e6%9e%90","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021090906000043653","title":{"rendered":"RedHill\u62a5\u544aMovantik\u6570\u636e\u5206\u6790"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/RedHill_Biopharma_Logo-3.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><p>&#8211; <i>\u5bf9<\/i><i>Movantik<sup>&reg;<\/sup><\/i><i>\uff08<\/i><i>naloxegol<\/i><i>\uff09\u6570\u636e\u7684\u4e24<\/i><i>\u9879\u65b0\u5206\u6790\u8bc4\u4f30\u4e86<\/i><i>Movantik<\/i><i>\u5728<\/i><i>65<\/i><i>\u5c81\u4ee5\u4e0a\u60a3\u8005\u4e9a\u7ec4\u4e2d\u7684\u5b89\u5168\u6027\u548c\u7597\u6548<\/i><\/p>\n<p>&#8211; <i>\u5728\u963f\u7247<\/i><i>\u7c7b\u836f\u7269\u9ad8\u5242\u91cf\u548c\u4f4e\u5242\u91cf\u6761\u4ef6\u4e0b\u8bc4\u4f30\u4e86<\/i><i>Movantik<\/i><i>\u7ec4\u4e0e\u5b89\u6170\u5242\u7ec4\u5bf9\u6bd4\u4e2d<\/i><i>Movantik<\/i><i>\u5bf9\u81ea\u4e3b\u6392\u4fbf\u548c\u5b8c\u5168\u81ea\u4e3b\u6392\u4fbf\u7684\u5feb\u901f\u548c\u6301\u7eed\u6539\u5584\u6548\u679c<\/i><\/p>\n<p>&#8211; <i>Movantik<\/i><i>\u662f\u7f8e\u56fd\u5e02<\/i><i>\u573a\u9886\u5148\u7684\u53e3\u670d\u5916\u5468\u4f5c\u7528<\/i><i>&micro;<\/i><i>\u578b\u963f\u7247\u53d7\u4f53\u62ee\u6297<\/i><i>\u5242<\/i><i>&nbsp;(PAMORA)<\/i><i>\uff0c<\/i><i>\u83b7\u51c6\u7528\u4e8e\u6cbb\u7597\u963f\u7247\u7c7b\u836f\u7269\u5728\u6162\u6027\u975e\u764c\u6027\u75bc\u75db\u60a3\u8005\u4e2d\u5f15\u8d77\u7684\u4fbf\u79d8<\/i><\/p>\n<p>\u4ee5\u8272\u5217\u7279\u62c9\u7ef4\u592b\u548c\u5317\u5361\u7f57\u83b1\u7eb3\u5dde\u7f57\u52292021\u5e749\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;&nbsp;\u4e13\u4e1a\u751f\u7269\u5236\u836f\u516c\u53f8<a target=\"_blank\" href=\"https:\/\/www.redhillbio.com\/\" rel=\"nofollow noopener\">RedHill Biopharma Ltd.<\/a>\uff08Nasdaq\u4ee3\u7801\uff1aRDHL\uff0c\u4ee5\u4e0b\u79f0\u201cRedHill\u201d\u6216\u201c\u516c\u53f8\u201d\uff09\u4eca\u5929\u5ba3\u5e03\u5728PAINWeek 2021\uff08\u7f8e\u56fd\u75bc\u75db\u5dde\u5927\u4f1a\uff09\u62a5\u544aMovantik<sup>&reg;<\/sup>\uff08naloxegol\uff093\u671f\u7814\u7a76\u6570\u636e\u7684\u4e09\u9879\u65b0\u5206\u6790\uff0c\u8bc1\u660e\u572865\u5c81\u53ca\u4ee5\u4e0a\u60a3\u8005\u4e9a\u7ec4\u4ee5\u53ca\u4f4e\u5242\u91cf\u548c\u9ad8\u5242\u91cf\u963f\u7247\u7c7b\u836f\u7269\u6cbb\u7597\u4e2d\u5747\u663e\u793a\u51fa\u5bf9\u963f\u7247\u7c7b\u836f\u7269\u6240\u81f4\u4fbf\u79d8\uff08OIC\uff09\u76f8\u5173\u6027\u5173\u952e\u75c7\u72b6\u80fd\u591f\u5feb\u901f\u8d77\u6548\u4e14\u5b9e\u73b0\u6301\u7eed\u548c\u53ef\u9884\u6d4b\u6539\u5584\u3002<\/p>\n<p>\u62a5\u544a\u4e2d\u6709\u4e24\u4efd\u79d1\u7814\u5899\u62a5\u4e13\u95e8\u9488\u5bf965\u5c81\u53ca\u4ee5\u4e0a\u7684\u60a3\u8005\u4e9a\u7ec4\uff0c\u663e\u793aMovantik\u7684\u7f13\u89e3\u7387\u663e\u8457\u4f18\u4e8e\u5b89\u6170\u5242\uff0c\u8d77\u6548\u8fc5\u901f\uff0c\u5728\u6cbb\u7597\u540e\u6700\u521d48\u5c0f\u65f6\u5185\u5b9e\u73b0\u81ea\u4e3b\u6392\u4fbf\uff08SBM\uff09\u548c\u5b8c\u5168\u81ea\u4e3b\u6392\u4fbf\uff08CSBM\uff09\u7684\u53d7\u8bd5\u8005\u6bd4\u4f8b\u66f4\u9ad8\u3002&nbsp;\u62a5\u544a\u7684\u5176\u4ed6\u6570\u636e\u8fd8\u8868\u660e\uff0c\u5305\u62ec\u4f4e\u4e8e100\u6beb\u514b\u5417\u5561\u5f53\u91cf\u7684\u5242\u91cf\u5728\u5185\uff0c\u65e0\u8bba\u5904\u65b9\u7684\u963f\u7247\u7c7b\u836f\u7269\u5242\u91cf\u5982\u4f55\uff0cnaloxegol\u5747\u4e3a\u60a3\u8005\u63d0\u4f9b\u4e86\u7c7b\u4f3c\u7684\u5feb\u901f\u4e14\u6301\u7eed\u7684\u75c7\u72b6\u6539\u5584\u3002&nbsp;\u4f5c\u8005\u5f97\u51fa\u7684\u7ed3\u8bba\u662f\uff0c\u5373\u4f7f\u4f7f\u7528\u8f83\u4f4e\u7684\u5417\u5561\u5f53\u91cf\u5242\u91cf\uff0c\u4e34\u5e8a\u533b\u751f\u5bf9\u8fd9\u4e9b\u60a3\u8005\u7684\u6cbb\u7597\u4e5f\u5e94\u8be5\u5ba1\u614e\u5bf9\u5f85\uff0c\u56e0\u4e3a\u4ed6\u4eec\u4ecd\u7136\u6613\u60a3OIC\u3002&nbsp;<\/p>\n<p>\u8fd9\u4e09\u9879\u5206\u6790\u5305\u62ec\u6765\u81ea\u4e24\u9879\u5927\u578b\u3001\u7a33\u5065\u3001\u5b8c\u5168\u76f8\u540c\u8bbe\u8ba1\u7684Movantik\u4e09\u671f\u7814\u7a76\u6c47\u603b\u6570\u636e\uff08Kodiak 4\u548cKodiak 5\uff1bNCT01309841\/NCT01323790\uff09\uff0c\u6d89\u53ca\u5206\u522b\u4f7f\u7528\u4e24\u79cd\u5242\u91cf\uff0812.5\u6beb\u514b\u548c25\u6beb\u514b\uff09\u7684891\u540d\u60a3\u8005\uff0c\u5b89\u6170\u5242\u7ec4\u5171\u6709446\u540d\u60a3\u8005\u3002&nbsp;<\/p>\n<p>\u201c\u9274\u4e8e\u591a\u8fbe90%\u7684\u8001\u5e74\u60a3\u8005\u5728\u63a5\u53d7\u963f\u7247\u7c7b\u836f\u7269\u6cbb\u7597\u6765\u5e2e\u52a9\u5e94\u5bf9\u6162\u6027\u75bc\u75db\uff0c\u5176\u4e2d\u591a\u8fbe86%\u60a3\u6709OIC\u75c7\u72b6\uff0c\u8fd9\u4e9b\u65b0\u7684\u5206\u6790\u5bf9\u4e8e\u5e2e\u52a9\u8fd9\u4e9b\u60a3\u8005\u5728\u4e0d\u589e\u52a0OIC\u75c7\u72b6\u7684\u60c5\u51b5\u4e0b\u83b7\u5f97\u6ee1\u610f\u7684\u75bc\u75db\u63a7\u5236\u800c\u8a00\u610f\u4e49\u5c24\u4e3a\u7a81\u51fa\u3002\u7531\u4e8e\u5408\u5e76\u75c7\u3001\u590d\u65b9\u7528\u836f\u548c\u8eab\u4f53\u6d3b\u52a8\u51cf\u5c11\uff0c\u8001\u5e74\u60a3\u8005\u5f80\u5f80\u66f4\u5bb9\u6613\u51fa\u73b0OIC\uff0c\u8ba9\u4ed6\u4eec\u83b7\u5f97Movantik\u8fd9\u6837\u5728\u8fd9\u4e00\u6311\u6218\u6027\u60a3\u8005\u7fa4\u4f53\u4e2d\u5b9e\u8bc1\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u81f3\u5173\u91cd\u8981\u3002\u201d <b>\u75bc\u75db\u7814\u7a76\u4eba<\/b><b>\u5458\u3001\u4e34\u5e8a\u533b\u751f\u517c\u7f8e\u56fd\u653f\u7b56\u4e2d\u5fc3\u9ad8\u7ea7\u7814\u7a76\u5458<\/b><b><span class=\"xn-person\">Lynn Webster<\/span><\/b><b>\u8868\u793a<\/b>\u3002<\/p>\n<p>\u201c\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u51fa\u73b0\u4e86\u4e00\u79cd\u8f6c\u53d8\uff0c\u4e5f\u5c31\u662f\u8981\u51cf\u5c11\u7528\u4e8e\u6cbb\u7597\u6162\u6027\u75bc\u75db\u7684\u963f\u7247\u7c7b\u836f\u7269\u5242\u91cf\u3002\u7136\u800c\uff0c\u5728\u4e0e\u6cbb\u7597\u76f8\u5173\u7684\u4fbf\u79d8\u65b9\u9762\uff0c\u4f4e\u5242\u91cf\u963f\u7247\u7c7b\u836f\u7269\u6cbb\u7597\u53ef\u80fd\u4e0e\u9ad8\u5242\u91cf\u6cbb\u7597\u4e00\u6837\u5e26\u6765\u96be\u9898\uff0c\u533b\u751f\u5fc5\u987b\u8ba4\u771f\u76d1\u6d4b\u60a3\u8005\u51fa\u73b0OIC\u7684\u8ff9\u8c61\uff0c\u201d <b>RedHill<\/b><b>\u9996\u5e2d\u79d1\u5b66\u5b98\u3001\u533b\u5b66\u535a\u58eb<\/b><b><span class=\"xn-person\">June Almenoff<\/span><\/b><b>\u8868\u793a<\/b>\u3002\u201c\u8fd9\u9879\u65b0\u7684\u5206\u6790\u663e\u793a\uff0c\u65e0\u8bba\u963f\u7247\u7c7b\u836f\u7269\u5242\u91cf\u5982\u4f55\uff0cMovantik\u7684\u7597\u6548\u5728\u901a\u8fc7OIC\u7ba1\u7406\u652f\u6301\u4e34\u5e8a\u8f6c\u5411\u4f4e\u5242\u91cf\u963f\u7247\u7c7b\u836f\u7269\u6cbb\u7597\u65b9\u9762\u540c\u7b49\u91cd\u8981\uff0c\u9884\u8ba1\u5728\u63a5\u53d7\u6162\u6027\u963f\u7247\u7c7b\u836f\u7269\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u670940-80%\u4f1a\u51fa\u73b0OIC[1]\u3002\u201d<\/p>\n<p><b><a target=\"_blank\" href=\"https:\/\/www.eventscribe.net\/2021\/PAINWeek\/agenda.asp?startdate=1\/1\/2001&amp;enddate=1\/1\/2001&amp;BCFO=&amp;pfp=Browse%20by%20Day&amp;tn=&amp;cpf2=&amp;cus2=&amp;pta=\" rel=\"nofollow noopener\">\u5728PAINWeek 2021\u4e0a\u62a5\u544a\u7684Movantik\uff08Naloxegol\uff09\u5206\u6790\u7ed3\u679c<\/a><\/b><b>\uff1a<\/b>&nbsp;<\/p>\n<p><b>\u5899\u62a5<\/b><b>1<\/b><b>\uff08<\/b><b>\u5899\u62a5\u7f16\u53f7<\/b><b>55<\/b><b>\uff09\uff1a<\/b><b><br \/>Naloxegol<\/b><b>\u4e3a\u8001\u5e74\u60a3\u8005\uff08<\/b><b>65<\/b><b>\u5c81\u53ca\u4ee5\u4e0a\uff09\u63d0\u4f9b\u4e86\u5feb\u901f\u5b9e\u73b0\u9996\u6b21\u81ea\u4e3b\u6392\u4fbf\uff08<\/b><b>SBM<\/b><b>\uff09\u3001\u5b8c\u5168<\/b><b>SBM<\/b><b>\u548c\u53ef<\/b><b>\u9884\u6d4b\u7684\u7597\u6548\uff1a\u4e24\u9879\u4e09\u671f\u7814\u7a76\u7684\u6c47\u603b\u5206\u6790<\/b><b><br \/><\/b>\u4f5c\u8005\uff1aLynn Webster\u3001Charles Argoff\u3001Charles H. McLeskey\u3001Carol B. Rockett\u3001Enoch Bortey\u3001Theresa Mallick-Searle\u3001Martin Hale<\/p>\n<p><b>\u5899\u62a5<\/b><b>2<\/b><b>\uff08<\/b><b>\u5899\u62a5\u7f16\u53f7<\/b><b>59<\/b><b>\uff09\uff1a<\/b><b><br \/>Naloxegol<\/b><b>\u4e3a<\/b><b>65<\/b><b>\u5c81\u53ca\u4ee5\u4e0a\u8001\u5e74\u60a3\u8005\u963f\u7247\u7c7b\u836f\u7269\u6240\u81f4\u4fbf\u79d8\uff08<\/b><b>OIC<\/b><b>\uff09\u63d0\u4f9b\u4e86\u5feb\u901f\u548c\u6301<\/b><b>\u7eed\u7684\u75c7\u72b6\u6539\u5584<\/b><b><br \/><\/b><b>\uff1a\u4e24<\/b><b>\u9879\u4e09\u671f\u7814\u7a76\u7684\u6c47\u603b\u5206\u6790<\/b><b><br \/><\/b>\u4f5c\u8005\uff1aMartin Hale\u3001Charles Argoff\u3001Charles H. McLeskey\u3001Carol B. Rockett\u3001Enoch Bortey\u3001Theresa Mallick-Searle\u3001Lynn Webster<\/p>\n<p><b>\u5899\u62a5<\/b><b>3<\/b><b>\uff08<\/b><b>\u5899\u62a5\u7f16\u53f7<\/b><b>30<\/b><b>\uff09\uff1a<\/b><b><br \/>Naloxegol<\/b><b>\u4e3a\u963f\u7247\u7c7b\u836f\u7269\u6240\u81f4\u4fbf\u79d8\uff08<\/b><b>OIC<\/b><b>\uff09\u75c7\u72b6\u63d0\u4f9b<\/b><b><br \/><\/b><b>\u4e0e\u963f\u7247<\/b><b>\u5242\u91cf\u65e0\u5173\u7684\u5feb\u901f\u548c\u6301\u7eed\u6539\u5584\uff1a\u4e24\u9879\u4e09\u671f\u7814\u7a76\u7684\u6c47\u603b\u5206\u6790<\/b><b><br \/><\/b>\u4f5c\u8005\uff1aJeffrey Gudin\u3001Jeremy A. Adler\u3001June Almenoff\u3001Carol B. Rockett\u3001Enoch Bortey\u3001Richard Rauck\u3001Lynn Webster<\/p>\n<p><b>\u5173\u4e8e<\/b><b>RedHill Biopharma&nbsp; &nbsp; <\/b><\/p>\n<p>RedHill Biopharma Ltd.\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1a<a target=\"_blank\" href=\"https:\/\/finance.yahoo.com\/quote\/RDHL?p=RDHL&amp;.tsrc=fin-srch\" rel=\"nofollow noopener\">RDHL<\/a>\uff09\u662f\u4e00\u5bb6\u4e3b\u8981\u4e13\u6ce8\u4e8e\u80c3\u80a0\u9053\u75be\u75c5\u548c\u4f20\u67d3\u75c5\u7684\u7279\u79cd\u751f\u7269\u5236\u836f\u516c\u53f8\u3002RedHill\u63a8\u5e7f\u4ee5\u4e0b\u80c3\u80a0\u9053\u836f\u7269\uff1a<b>Movantik<sup>&reg;<\/sup><\/b>\u7528\u4e8e\u6cbb\u7597\u963f\u7247\u7c7b\u836f\u7269\u5f15\u8d77\u7684\u6210\u4eba\u4fbf\u79d8<sup>[2]<\/sup>\u3001<b>Talicia<sup>&reg;<\/sup><\/b>\u6cbb\u7597\u6210\u4eba\u5e7d\u95e8\u87ba\u65cb\u6746\u83cc<i>\uff08<\/i><i>H. pylori<\/i><i>\uff09<\/i>\u611f\u67d3<sup>[3]<\/sup><b>Aemcolo<sup>&reg;<\/sup><\/b>\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u65c5\u884c\u8005\u8179\u6cfb<sup>[4]<\/sup>\u3002RedHill\u7684\u5173\u952e\u4e34\u5e8a\u540e\u671f\u5f00\u53d1\u8ba1\u5212\u5305\u62ec\uff1a(i) <b>RHB-204<\/b>\uff0c\u8ba1\u5212\u8fdb\u884c\u4e00\u9879\u9488\u5bf9\u80ba\u90e8\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\uff08NTM\uff09\u75be\u75c5\u611f\u67d3\u76843\u671f\u7814\u7a76\uff1b(ii) <b>opaganib<\/b><b>\uff08<\/b><b>ABC294640<\/b><b>\uff09<\/b>\uff0c\u4e00\u79cd\u540c\u7c7b\u9996\u521b\u7684\u9488\u5bf9\u591a\u79cd\u9002\u5e94\u75c7\u7684\u53e3\u670dSK2\u9009\u62e9\u6027\u6291\u5236\u5242\uff0c\u9488\u5bf9\u65b0\u51a0\u80ba\u708e\u7684\u5168\u74032\/3\u671f\u53e3\u670d\u836f\u7269\u9879\u76ee\u548c\u9488\u5bf9\u524d\u5217\u817a\u764c\u548c\u80c6\u7ba1\u764c\u76842\u671f\u7814\u7a76\uff1b(iii) <b>RHB-107<\/b> (<b>upamostat<\/b>)\uff0c\u4e00\u79cd\u53e3\u670d\u4e1d\u6c28\u9178\u86cb\u767d\u9176\u6291\u5236\u5242\uff0c\u6b63\u5728\u7f8e\u56fd\u8fdb\u884c\u9488\u5bf9\u75c7\u72b6\u578b\u65b0\u51a0\u80ba\u708e\u76842\/3\u671f\u7814\u7a76\uff0c\u5e76\u9776\u5411\u591a\u79cd\u5176\u4ed6\u764c\u75c7\u548c\u708e\u75c7\u6027\u80c3\u80a0\u75be\u75c5\uff1b(iv) <b>RHB-104<\/b>\uff0c\u5728\u514b\u7f57\u6069\u75c5\u7684\u9996\u6b213\u671f\u7814\u7a76\u4e2d\u83b7\u5f97\u79ef\u6781\u7ed3\u679c\uff1b(v) <b>RHB-102<\/b>\uff0c\u5728\u6025\u6027\u80c3\u80a0\u708e\u548c\u80c3\u708e\u76843\u671f\u7814\u7a76\u4e2d\u83b7\u5f97\u79ef\u6781\u7ed3\u679c\uff0c\u5728IBS-D\u76842\u671f\u7814\u7a76\u4e2d\u83b7\u5f97\u79ef\u6781\u7ed3\u679c\uff1b\u548c&nbsp;(vi) <b>RHB<\/b>&#8211;<b>106<\/b>\uff0c\u4e00\u79cd\u5c01\u88c5\u7684\u80a0\u5236\u5242\u3002\u516c\u53f8\u66f4\u591a\u76f8\u5173\u4fe1\u606f\u8bf7\u89c1<a target=\"_blank\" href=\"http:\/\/www.redhillbio.com\/\" rel=\"nofollow noopener\">www.redhillbio.com<\/a>&nbsp;\/ <a target=\"_blank\" href=\"https:\/\/twitter.com\/RedHillBio\" rel=\"nofollow noopener\">https:\/\/twitter.com\/RedHillBio<\/a>\u3002<\/p>\n<p><b>\u5173\u4e8e<\/b><b>Movantik<\/b>&nbsp;<b>&reg;<\/b> <b>\uff08<\/b><b>naloxegol<\/b><b>\uff09<\/b>&nbsp;<\/p>\n<p>Movantik&reg;\u662f\u4e00\u79cd\u963f\u7247\u62ee\u6297\u5242\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u6210\u5e74\u6162\u6027\u975e\u764c\u75db\u60a3\u8005\u7684\u963f\u7247\u7c7b\u836f\u7269\u6240\u81f4\u4fbf\u79d8\uff08OIC\uff09\uff0c\u5305\u62ec\u4e0d\u9700\u8981\u9891\u7e41\uff08\u4f8b\u5982\u6bcf\u5468\uff09\u589e\u52a0\u963f\u7247\u7c7b\u836f\u7269\u5242\u91cf\u7684\u65e2\u5f80\u764c\u75c7\u6216\u5176\u6cbb\u7597\u76f8\u5173\u6027\u6162\u6027\u75bc\u75db\u60a3\u8005\u3002<\/p>\n<p><b>\u5173\u4e8e<\/b><b>Movantik<\/b><b>\u7684\u91cd\u8981\u5b89\u5168\u4fe1\u606f<\/b>&nbsp;<\/p>\n<p>Movantik<sup>&reg;<\/sup>\uff08naloxegol\uff09\u6709\u4ee5\u4e0b\u7981\u5fcc\uff1a<\/p>\n<ul type=\"disc\">\n<li>\u6709\u5df2\u77e5\u6216\u7591\u4f3c\u80c3\u80a0\u9053\uff08GI\uff09\u6897\u963b\u7684\u60a3\u8005\u548c\u7531\u4e8e\u53ef\u80fd\u53d1\u751fGI\u7a7f\u5b54\u800c\u6709\u590d\u53d1\u6027\u6897\u963b\u98ce\u9669\u7684\u60a3\u8005\u3002 <\/li>\n<li>\u63a5\u53d7\u5f3aCYP3A4\u6291\u5236\u5242\uff08\u4f8b\u5982\u514b\u62c9\u9709\u7d20\u3001\u916e\u5eb7\u5511\uff09\u7684\u60a3\u8005\uff1b\u7531\u4e8e\u8fd9\u4e9b\u836f\u7269\u4f1a\u663e\u7740\u589e\u52a0naloxegol\u66b4\u9732\uff0c\u4ece\u800c\u7a81\u53d1\u963f\u7247\u7c7b\u836f\u7269\u6212\u65ad\u75c7\u72b6\u3002 <\/li>\n<li>\u5df2\u77e5\u5bf9Movantik\u6216\u5176\u4efb\u4f55\u8d4b\u5f62\u5242\u6709\u4e25\u91cd\u6216\u91cd\u5ea6\u8fc7\u654f\u53cd\u5e94\u7684\u60a3\u8005\u3002<\/li>\n<\/ul>\n<p>\u63a5\u53d7Movantik\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u51fa\u73b0\u8fc7\u4e0e\u963f\u7247\u7c7b\u836f\u7269\u6212\u65ad\u4e00\u81f4\u7684\u75c7\u72b6\uff0c\u5305\u62ec\u591a\u6c57\u3001\u5bd2\u6218\u3001\u8179\u6cfb\u3001\u8179\u75db\u3001\u7126\u8651\u3001\u6613\u6012\u548c\u6253\u54c8\u6b20\u3002\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u89c2\u5bdf\u5230\uff0c\u4e0e\u63a5\u53d7\u5176\u4ed6\u963f\u7247\u7c7b\u836f\u7269\u7684\u60a3\u8005\u76f8\u6bd4\uff0c\u63a5\u53d7\u7f8e\u6c99\u916e\u6cbb\u7597\u75bc\u75db\u7684\u60a3\u8005\u53d1\u751f\u53ef\u80fd\u4e0e\u963f\u7247\u7c7b\u836f\u7269\u6212\u65ad\u6709\u5173\u7684\u80c3\u80a0\u9053\u4e0d\u826f\u53cd\u5e94\u9891\u7387\u66f4\u9ad8\u3002\u8840\u8111\u5c4f\u969c\u53d7\u635f\u7684\u60a3\u8005\u6709\u66f4\u5927\u7684\u963f\u7247\u7c7b\u836f\u7269\u6212\u65ad\u6216\u9547\u75db\u51cf\u9000\u98ce\u9669\u3002\u8fd9\u4e9b\u60a3\u8005\uff08\u5982\u591a\u53d1\u6027\u786c\u5316\u75c7\u3001\u8fd1\u671f\u5927\u8111\u635f\u4f24\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u672a\u5f97\u5230\u63a7\u5236\u7684\u766b\u75eb\uff09\u672a\u88ab\u7eb3\u5165\u4e34\u5e8a\u7814\u7a76\u3002\u5728\u8fd9\u7c7b\u60a3\u8005\u4e2d\u4f7f\u7528Movantik\u65f6\uff0c\u5e94\u8003\u8651\u6574\u4f53\u98ce\u9669\u83b7\u76ca\u60c5\u51b5\u3002\u5728\u6b64\u7c7b\u60a3\u8005\u4e2d\u4f7f\u7528Movantik\u65f6\u5e94\u76d1\u6d4b\u963f\u7247\u7c7b\u836f\u7269\u6212\u65ad\u75c7\u72b6\u3002<\/p>\n<p>\u4e25\u91cd\u8179\u75db\u548c\/\u6216\u8179\u6cfb\u6709\u8fc7\u62a5\u544a\uff0c\u901a\u5e38\u662f\u5728\u5f00\u59cb\u4f7f\u7528Movantik\u540e\u7684\u51e0\u5929\u5185\u53d1\u751f\u3002\u5982\u679c\u51fa\u73b0\u4e25\u91cd\u75c7\u72b6\uff0c\u5e94\u89c2\u5bdf\u5e76\u505c\u6b62\u7528\u836f\u3002\u8003\u8651\u6bcf\u5929\u4e00\u6b21\u4ee512.5\u6beb\u514b\u91cd\u65b0\u5f00\u59cbMovantik\u7528\u836f\u3002<\/p>\n<p>\u5df2\u6709\u4f7f\u7528\u5305\u62ecMovantik\u5728\u5185\u7684\u5916\u5468\u4f5c\u7528\u963f\u7247\u62ee\u6297\u5242\u5bfc\u81f4\u80c3\u80a0\u9053\u7a7f\u5b54\u7684\u75c5\u4f8b\u62a5\u544a\u3002Movantik\u4e0a\u5e02\u540e\u7528\u4e8e\u6709\u80c3\u80a0\u9053\u7a7f\u5b54\u98ce\u9669\u7684\u60a3\u8005\uff08\u4f8b\u5982\uff0c\u6d78\u6da6\u6027\u80c3\u80a0\u9053\u6076\u6027\u80bf\u7624\u3001\u8fd1\u671f\u80c3\u80a0\u9053\u624b\u672f\u3001\u5305\u62ec\u61a9\u5ba4\u708e\u5728\u5185\u7684\u61a9\u5ba4\u75c5\u3001\u7f3a\u8840\u6027\u7ed3\u80a0\u708e\u6216\u4f7f\u7528\u8d1d\u4f10\u5355\u6297\u4f34\u968f\u6cbb\u7597\uff09\u65f6\uff0c\u66fe\u6709\u5305\u62ec\u81f4\u6b7b\u75c5\u4f8b\u5728\u5185\u7684\u80c3\u80a0\u9053\u7a7f\u5b54\u75c5\u4f8b\u62a5\u544a\u3002\u76d1\u6d4b\u91cd\u5ea6\u3001\u6301\u7eed\u6216\u6076\u5316\u7684\u8179\u75db\uff1b\u5982\u679c\u51fa\u73b0\u8fd9\u79cd\u75c7\u72b6\u5e94\u505c\u6b62\u7528\u836f\u3002<\/p>\n<p>\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0cMovantik\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\u662f\uff1a\u8179\u75db\uff0821%\u5bf97%\uff09\u3001\u8179\u6cfb\uff089%\u5bf95%\uff09\u3001\u6076\u5fc3\uff088%\u5bf95%\uff09\u3001\u80a0\u80c3\u6c14\u80c0\uff086%\u5bf93%)\u3001\u5455\u5410\uff085%\u5bf94%\uff09\u3001\u5934\u75db\uff084%\u5bf93%\uff09\u548c\u591a\u6c57\u75c7\uff083%\u5bf9&lt;1%\uff09\u3002<\/p>\n<p>Movantik\uff08naloxegol\uff09\u9002\u7528\u4e8e\u6cbb\u7597\u6210\u5e74\u6162\u6027\u975e\u764c\u75db\u60a3\u8005\u7684\u963f\u7247\u7c7b\u836f\u7269\u6240\u81f4\u4fbf\u79d8\uff08OIC\uff09\uff0c\u5305\u62ec\u4e0d\u9700\u8981\u9891\u7e41\uff08\u4f8b\u5982\u6bcf\u5468\uff09\u589e\u52a0\u963f\u7247\u7c7b\u836f\u7269\u5242\u91cf\u7684\u65e2\u5f80\u764c\u75c7\u6216\u5176\u6cbb\u7597\u76f8\u5173\u6027\u6162\u6027\u75bc\u75db\u60a3\u8005\u3002<\/p>\n<p>\u70b9\u51fb\u6b64\u5904\u4e86\u89e3Movantik\u7684<a target=\"_blank\" href=\"https:\/\/movantik.com\/pdf\/MovantikMedicationGuide.pdf\" rel=\"nofollow noopener\">\u7528\u836f\u6307\u5357<\/a>\u548c\u5b8c\u6574<a target=\"_blank\" href=\"https:\/\/movantik.com\/pdf\/MovantikPrescribingInformation.pdf\" rel=\"nofollow noopener\">\u5904\u65b9\u4fe1\u606f<\/a>\u3002<\/p>\n<p>\u6211\u4eec\u9f13\u52b1\u60a8\u901a\u8fc71-833-ADRHILL\uff081-833-237-4455\uff09\u5411RedHill Biopharma Inc.\u62a5\u544a\u4e0d\u826f\u53cd\u5e94\uff0c\u4e5f\u53ef\u4ee5\u901a\u8fc71-800-FDA-1088\u6216<a target=\"_blank\" href=\"http:\/\/www.fda.gov\/medwatch\" rel=\"nofollow noopener\">www.fda.gov\/medwatch<\/a>\u5411FDA\u62a5\u544a\u3002<\/p>\n<p>MOVANTIK\u662f\u963f\u65af\u5229\u5eb7\u516c\u53f8\u96c6\u56e2\u7684\u6ce8\u518c\u5546\u6807\u3002<\/p>\n<p><i>\u6ce8\u610f\uff1a\u672c\u65b0<\/i><i>\u95fb\u7a3f\u662f\u516c\u53f8\u4ee5\u82f1\u6587\u53d1\u5e03\u7684\u5b98\u65b9\u65b0\u95fb\u7a3f\u7684\u8bd1\u6587\uff0c\u4e3a\u65b9\u4fbf\u67e5\u9605\u800c\u63d0\u4f9b\u3002\u5982\u9700\u83b7\u5f97\u82f1\u6587\u7248\u5b8c\u6574\u65b0\u95fb\u7a3f\uff0c\u5305\u62ec\u524d\u77bb\u6027\u58f0\u660e\u7684\u514d\u8d23\u58f0\u660e\uff0c\u8bf7\u8bbf\u95ee\uff1a<\/i><i><a target=\"_blank\" href=\"https:\/\/ir.redhillbio.com\/press-releases\" rel=\"nofollow noopener\">https:\/\/ir.redhillbio.com\/press-releases<\/a><\/i><i>&nbsp;&nbsp;<\/i>&nbsp;<\/p>\n<div>\n<table cellspacing=\"0\" cellpadding=\"0\" border=\"0\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\">&nbsp;<\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u516c\u53f8<\/b><b>\u8054\u7cfb\u4eba\uff1a<\/b>&nbsp;<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">Adi Frish <\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u9996\u5e2d\u4f01\u4e1a\u548c\u4e1a\u52a1\u53d1\u5c55\u5b98&nbsp;<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">RedHill Biopharma <\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u7535\u8bdd\uff1a+972-54-6543-112 <\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:adi@redhillbio.com\" class=\"prnews_a\" rel=\"nofollow noopener\">adi@redhillbio.com<\/a>&nbsp;<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\">&nbsp;<\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u5a92\u4f53<\/b><b>\u8054\u7cfb\u4eba\uff1a<\/b>&nbsp;<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u7f8e\u56fd\uff1a<\/b>&nbsp;Bryan Gibbs, Finn Partners <\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u7535\u8bdd\uff1a+1 212 529 2236 <\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:bryan.gibbs@finnpartners.com\" class=\"prnews_a\" rel=\"nofollow noopener\">bryan.gibbs@finnpartners.com<\/a>&nbsp;<\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><b>\u82f1\u56fd\uff1a<\/b>&nbsp;Amber Fennell, Consilium <\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\">+44\uff080\uff097739 658 783 &nbsp; <\/span><\/p>\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a target=\"_blank\" href=\"mailto:fennell@consilium-comms.com\" class=\"prnews_a\" rel=\"nofollow noopener\">fennell@consilium-comms.com<\/a>&nbsp;<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>&nbsp;<\/p>\n[1] Crockett, Seth D., et al. American Gastroenterological Association Institute guideline on the medical management of opioid-induced constipation, Gastroenterology 156.1 (2019): 218-226.<\/p>\n[2] \u6709\u5173Movantik<sup>&reg;<\/sup>\uff08naloxegol\uff09\u7684\u5b8c\u6574\u5904\u65b9\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1a<a target=\"_blank\" href=\"http:\/\/www.movantik.com\/\" rel=\"nofollow noopener\">www.Movantik.com<\/a>\u3002&nbsp; <\/p>\n[3] \u6709\u5173Talicia<sup>&reg;<\/sup>\uff08\u5965\u7f8e\u62c9\u5511\u9541\u3001\u963f\u83ab\u897f\u6797\u548c\u5229\u798f\u5e03\u6c40\uff09\u7684\u5b8c\u6574\u5904\u65b9\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1a<a target=\"_blank\" href=\"http:\/\/www.talicia.com\/\" rel=\"nofollow noopener\">www.Talicia.com<\/a>\u3002&nbsp; <\/p>\n[4] \u6709\u5173Aemcolo<sup>&reg;<\/sup>\uff08\u5229\u798f\u9709\u7d20\uff09\u7684\u5b8c\u6574\u5904\u65b9\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee<a target=\"_blank\" href=\"http:\/\/www.aemcolo.com\/\" rel=\"nofollow noopener\">www.Aemcolo.com<\/a>\u3002<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8211; 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\u5899\u62a51\uff08\u5899\u62a5\u7f16\u53f755\uff09\uff1aNaloxegol\u4e3a\u8001\u5e74\u60a3\u8005\uff0865\u5c81\u53ca\u4ee5\u4e0a\uff09\u63d0\u4f9b\u4e86\u5feb\u901f\u5b9e\u73b0\u9996\u6b21\u81ea\u4e3b\u6392\u4fbf\uff08SBM\uff09\u3001\u5b8c\u5168SBM\u548c\u53ef\u9884\u6d4b\u7684\u7597\u6548\uff1a\u4e24\u9879\u4e09\u671f\u7814\u7a76\u7684\u6c47\u603b\u5206\u6790\u4f5c\u8005\uff1aLynn Webster\u3001Charles Argoff\u3001Charles H. McLeskey\u3001Carol B. Rockett\u3001Enoch Bortey\u3001Theresa Mallick-Searle\u3001Martin Hale \u5899\u62a52\uff08\u5899\u62a5\u7f16\u53f759\uff09\uff1aNaloxegol\u4e3a65\u5c81\u53ca\u4ee5\u4e0a\u8001\u5e74\u60a3\u8005\u963f\u7247\u7c7b\u836f\u7269\u6240\u81f4\u4fbf\u79d8\uff08OIC\uff09\u63d0\u4f9b\u4e86\u5feb\u901f\u548c\u6301\u7eed\u7684\u75c7\u72b6\u6539\u5584\uff1a\u4e24\u9879\u4e09\u671f\u7814\u7a76\u7684\u6c47\u603b\u5206\u6790\u4f5c\u8005\uff1aMartin Hale\u3001Charles Argoff\u3001Charles H. McLeskey\u3001Carol B. Rockett\u3001Enoch Bortey\u3001Theresa Mallick-Searle\u3001Lynn Webster \u5899\u62a53\uff08\u5899\u62a5\u7f16\u53f730\uff09\uff1aNaloxegol\u4e3a\u963f\u7247\u7c7b\u836f\u7269\u6240\u81f4\u4fbf\u79d8\uff08OIC\uff09\u75c7\u72b6\u63d0\u4f9b\u4e0e\u963f\u7247\u5242\u91cf\u65e0\u5173\u7684\u5feb\u901f\u548c\u6301\u7eed\u6539\u5584\uff1a\u4e24\u9879\u4e09\u671f\u7814\u7a76\u7684\u6c47\u603b\u5206\u6790\u4f5c\u8005\uff1aJeffrey Gudin\u3001Jeremy A. Adler\u3001June Almenoff\u3001Carol B. Rockett\u3001Enoch Bortey\u3001Richard Rauck\u3001Lynn Webster \u5173\u4e8eRedHill&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2021090906000043653\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":43656,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-43653","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/43653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=43653"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/43653\/revisions"}],"predecessor-version":[{"id":43655,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/43653\/revisions\/43655"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/43656"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=43653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=43653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=43653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}