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\"\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5317\u4eac2021\u5e749\u67083\u65e5 \/\u7f8e\u901a\u793e\/ — \u503c2021\u5e74\u4e2d\u56fd\u56fd\u9645\u670d\u52a1\u8d38\u6613\u4ea4\u6613\u4f1a\u53ec\u5f00\u4e4b\u9645\uff0c\u81f4\u529b\u4e8e\u5728\u80bf\u7624\u3001\u4e59\u809d\u53ca\u4e0e\u8870\u8001\u76f8\u5173\u75be\u75c5\u7b49\u6cbb\u7597\u9886\u57df\u5f00\u53d1\u521b\u65b0\u836f\u7269\u7684\u9886\u5148\u7684\u751f\u7269\u533b\u836f\u4f01\u4e1a — \u4e9a\u76db\u533b\u836f\uff086855.HK\uff09\u4eca\u65e5\u4e0e\u5eb7\u5723\u73af\u7403\u57fa\u56e0\u6280\u672f\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u79f0\u201c\u5eb7\u5723\u73af\u7403\u201d\uff09\u5728\u670d\u8d38\u4f1a\u4e0a\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u5907\u5fd8\u5f55\u3002\u5408\u4f5c\u8fbe\u6210\u540e\uff0c\u53cc\u65b9\u5c06\u52a0\u5f3a\u670d\u52a1\u8d44\u6e90\u4e0e\u4fe1\u606f\u8d44\u6e90\u5bf9\u63a5\uff0c\u5c31\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u751f\u7269\u6807\u5fd7\u7269\u7684\u7814\u7a76\u53ca\u8f6c\u5316\u5c55\u5f00\u6df1\u5ea6\u5408\u4f5c\uff0c\u5e76\u5171\u540c\u63a2\u7d22\u63d0\u5347\u8840\u6db2\u80bf\u7624\u76f8\u5173\u751f\u7269\u6807\u8bb0\u7269\u68c0\u6d4b\u65b9\u6cd5\u7684\u53ef\u53ca\u6027\u3002<\/p>\n

\n

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\u4e9a\u76db\u533b\u836f\u8463\u4e8b\u957f\u3001CEO\u6768\u5927\u4fca\u535a\u58eb\uff08\u5de6\uff09\u4e0e\u5eb7\u5723\u73af\u7403\u6267\u884c\u8463\u4e8b\u3001CEO\u9ec4\u58eb\u6602\u6559\u6388\uff08\u53f3\uff09\u5728\u7b7e\u7ea6\u540e\u5408\u5f71\u7559\u5ff5<\/span><\/p>\n<\/p><\/div>\n

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\u8840\u6db2\u80bf\u7624\u662f\u4e9a\u76db\u533b\u836f\u4ea7\u54c1\u7ba1\u7ebf\u7684\u91cd\u8981\u7814\u53d1\u65b9\u5411\u4e4b\u4e00\uff0c\u516c\u53f8\u591a\u4e2a\u5728\u7814\u54c1\u79cd\u5728\u8be5\u75be\u75c5\u6cbb\u7597\u65b9\u9762\u5448\u73b0\u4e86\u6f5c\u529b\uff1b\u800c\u5eb7\u5723\u73af\u7403\u662f\u8840\u6db2\u7279\u68c0\u7ec6\u5206\u9886\u57df\u7684\u5934\u90e8\u4f01\u4e1a\u3002\u6211\u4eec\u975e\u5e38\u671f\u5f85\u53cc\u65b9\u540e\u7eed\u7684\u6df1\u5165\u5408\u4f5c\uff0c\u8fd9\u5c06\u5b9e\u73b0\u4e2d\u56fd\u521b\u65b0\u4f01\u4e1a\u5728\u836f\u7269\u7814\u53d1\u548c\u5546\u4e1a\u5316\u4e0a\u7684\u5f3a\u5f3a\u8054\u5408\u53ca\u4f18\u52bf\u4e92\u8865\uff0c\u5728\u4e2d\u56fd\u8840\u6db2\u80bf\u7624\u7cbe\u51c6\u5316\u6cbb\u7597\u8fdb\u7a0b\u4e2d\u5177\u6709\u5212\u65f6\u4ee3\u7684\u91cc\u7a0b\u7891\u610f\u4e49\u3002\u201d<\/span><\/p>\n

\u5eb7\u5723\u73af\u7403\u6267\u884c\u8463\u4e8b\u3001<\/b>CEO<\/b>\u9ec4\u58eb\u6602\u6559\u6388<\/b>\u8868\u793a\uff1a\u201c\u5eb7\u5723\u73af\u7403\u81ea\u8bde\u751f\u4e4b\u65e5\u8d77\uff0c\u957f\u671f\u6df1\u8015\u8840\u6db2\u5b66\u9886\u57df\u5e76\u63d0\u4f9b\u7279\u68c0\u670d\u52a1\uff1a\u81ea2003\u5e74\u59cb\u81f3\u4eca\uff0c\u5eb7\u5723\u73af\u7403\u6301\u7eed\u5728CML\u4f34\u968f\u8bca\u65ad\u9886\u57df\u4e3a\u4e34\u5e8a\u4e0e\u60a3\u8005\u63d0\u4f9b\u7279\u68c0\u670d\u52a1\uff1b2010\u5e74\u81f32020\u5e74\u95f4\uff0c\u5df2\u7d2f\u8ba1\u5b8c\u6210\u8d8520\u4e07\u4f8b\u6b21\u68c0\u9a8c\u3002\u51ed\u501f\u56e2\u961f\u4e30\u5bcc\u7684\u7ecf\u9a8c\u548c\u5f3a\u5927\u7684\u7814\u53d1\u80fd\u529b\uff0c\u4f8b\u5982\u68c0\u6d4bBCR-ABL\u4e0d\u540c\u878d\u5408\u7c7b\u578b\u7684\u7075\u654f\u5ea6\u53ef\u8fbe10(-5)<\/sup>\u4ee5\u4e0a\uff0c\u57fa\u4e8e\u4e8c\u4ee3\u6d4b\u5e8f\u6280\u672f\u7684ABL\u6fc0\u9176\u533a\u7a81\u53d8\u68c0\u51fa\u7387\u8fbe\u523016%\uff0c\u8bca\u7597\u6280\u672f\u7684\u63d0\u5347\u5c06\u5bf9\u60a3\u8005\u7684\u4e34\u5e8a\u6cbb\u7597\u65b9\u6848\u3001\u836f\u7269\u7597\u6548\u76d1\u6d4b\u548c\u5168\u75c5\u7a0b\u89c4\u8303\u5316\u7ba1\u7406\u63d0\u4f9b\u6709\u529b\u652f\u6301\u3002<\/p>\n

\u4f5c\u4e3a\u901a\u8fc7\u56fd\u9645\u6807\u51c6\u5316\u8ba4\u8bc1\u7684\u5546\u4e1a\u5b9e\u9a8c\u5ba4\uff0c\u5eb7\u5723\u73af\u7403\u591a\u6b21\u4e0e\u5168\u7403\u77e5\u540d\u5236\u836f\u516c\u53f8\u53ca\u56fd\u5185\u5b98\u65b9\u534f\u4f1a\u7684\u5408\u4f5c\u7ecf\u9a8c\uff1b\u4e9a\u76db\u533b\u836f\u662f\u56fd\u5185\u8840\u6db2\u80bf\u7624\u9886\u57df\u836f\u7269\u7814\u53d1\u4e3b\u529b\uff0c\u5eb7\u5723\u73af\u7403\u5bf9\u53cc\u65b9\u80fd\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u975e\u5e38\u91cd\u89c6\u548c\u671f\u5f85\u3002\u672a\u6765\uff0c\u53cc\u65b9\u5c06\u5728\u8840\u6db2\u75c5\u9886\u57df\u8fbe\u6210\u5168\u9762\u5408\u4f5c\u3002\u5eb7\u5723\u73af\u7403\u6709\u4fe1\u5fc3\u8054\u5408\u4e9a\u76db\u533b\u836f\u4e3a\u4e2d\u56fd\u8840\u6db2\u75c5\u60a3\u8005\u5728\u8bca\u65ad\u3001\u6cbb\u7597\u9886\u57df\u643a\u624b\u63a2\u7d22\uff0c\u5171\u63a8\u4e2d\u56fd\u75c5\u60a3\u7684\u7cbe\u51c6\u8bca\u7597\u8fdb\u7a0b\u3001\u5171\u521b\u4e2d\u56fd\u4f01\u4e1a\u5728\u79d1\u6280\u9a71\u52a8\u4e0b\u7684\u521b\u65b0\u53d1\u5c55\u4e4b\u8def\uff0c\u5728\u5f53\u4ee3\u793e\u4f1a\u533b\u7597\u670d\u52a1\u4f53\u7cfb\u4e0b\u8d21\u732e\u5168\u65b0\u4ef7\u503c\uff01\u201d<\/p>\n

\u4e0e\u5eb7\u5723\u73af\u7403\u7684\u6218\u7565\u5408\u4f5c\uff0c\u5c06\u6210\u4e3a\u4e9a\u76db\u533b\u836f\u6838\u5fc3\u4ea7\u54c1\u5965\u96f7\u5df4\u66ff\u5c3c\uff08Olverembatinib\uff0cHQP1351\uff0c\u66fe\u7528\u540d\u8010\u514b\u66ff\u5c3c\u3001\u5965\u745e\u5df4\u66ff\u5c3c\uff09\u5546\u4e1a\u5316\u5e03\u5c40\u4e2d\u7684\u91cd\u8981\u4e00\u6b65\uff0c\u5e76\u63a8\u52a8\u4e2d\u56fdCML\u60a3\u8005\u7684\u7cbe\u51c6\u5316\u6cbb\u7597\u3002<\/p>\n

CML\u662f\u9aa8\u9ad3\u9020\u8840\u5e72\u7ec6\u80de\u514b\u9686\u6027\u589e\u6b96\u5f62\u6210\u7684\u6076\u6027\u80bf\u7624\uff0c\u5168\u7403\u670938%\u7684\u65b0\u53d1CML\u60a3\u8005\u5728\u4e2d\u56fd[1]<\/sup>\u3002\u968f\u7740\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08TKI\uff09\u836f\u7269\u8fdb\u5165\u4e34\u5e8a\uff0c\u6162\u6027\u7c92\u7ec6\u80de\u767d\u8840\u75c5\uff08CML\uff09\u7684\u6cbb\u7597\u6a21\u5f0f\u53d1\u751f\u4e86\u6781\u5927\u6539\u53d8\u3002\u5c3d\u7ba1TKI\u663e\u8457\u6539\u5584\u4e86CML\u60a3\u8005\u7684\u9884\u540e\uff0c\u4f46\u4ecd\u6709\u90e8\u5206\u60a3\u8005\u5728\u6cbb\u7597\u4e2d\u51fa\u73b0\u8010\u836f\u3002\u5176\u4e2dT315I\u7a81\u53d8\u662f\u5e38\u89c1\u7684\u8010\u836f\u7a81\u53d8\u7c7b\u578b\u4e4b\u4e00\uff0c\u5728\u8010\u836fCML\u4e2d\u7684\u53d1\u751f\u7387\u53ef\u8fbe25%\u5de6\u53f3\u3002\u4f34\u6709T315I\u7a81\u53d8\u7684CML\u60a3\u8005\u5bf9\u76ee\u524d\u6240\u6709\u4e00\u4ee3\u3001\u4e8c\u4ee3BCR-ABL\u6291\u5236\u5242\u5747\u8010\u836f\uff0c\u6b63\u9762\u4e34\u65e0\u836f\u53ef\u533b\u6cbb\u7684\u7a98\u5883\u3002<\/p>\n

\u5965\u96f7\u5df4\u66ff\u5c3c\u662f\u4e2d\u56fd\u9996\u4e2a\u7b2c\u4e09\u4ee3BCR-ABL\u9776\u5411\u8010\u836fCML\u6cbb\u7597\u836f\u7269\uff0c\u9776\u5411\u5305\u62ecT315I\u7a81\u53d8\u5728\u5185\u7684\u591a\u79cdBCR-ABL\u7a81\u53d8\u4f53\u3002\u76ee\u524d\uff0c\u5965\u96f7\u5df4\u66ff\u5c3c\u5df2\u5728\u4e2d\u56fd\u63d0\u4ea4\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\uff0c\u4e14\u5df2\u88abCDE\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u548c\u7a81\u7834\u6027\u6cbb\u7597\u54c1\u79cd\u3002\u5965\u96f7\u5df4\u66ff\u5c3c\u4e0a\u5e02\u540e\uff0c\u5c06\u6ee1\u8db3\u4e2d\u56fd\u643aT315I\u7a81\u53d8CML\u60a3\u8005\u5de8\u5927\u7684\u4e9f\u5f85\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\u3002<\/p>\n

\u4e9a\u76db\u533b\u836f\u4e0e\u5eb7\u5723\u73af\u7403\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u540e\uff0c\u53cc\u65b9\u5c06\u63a2\u7d22\u63d0\u9ad8\u4e2d\u56fdT315I\u68c0\u6d4b\u7684\u53ef\u53ca\u6027\uff0c\u5b9e\u73b0\u643aT315I\u7a81\u53d8CML\u60a3\u8005\u7684\u7cbe\u51c6\u7b5b\u67e5\uff0c\u5e2e\u52a9\u5176\u5c3d\u5feb\u63a5\u53d7\u7cbe\u51c6\u6709\u6548\u7684\u836f\u7269\u6cbb\u7597\uff1b\u5e76\u63a8\u52a8CML\u60a3\u8005\u7684\u7cbe\u51c6\u5316\u548c\u4e2a\u6027\u5316\u6cbb\u7597\uff0c\u4e3a\u66f4\u591a\u60a3\u8005\u5e26\u6765\u957f\u671f\u751f\u5b58\u83b7\u76ca\u3002<\/p>\n

\u53c2\u8003\u6587\u732e
<\/b>1. Decision Resources Group 2017 data<\/p>\n

\u5173\u4e8e\u4e9a\u76db\u533b\u836f<\/b><\/p>\n

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\u5173\u4e8e\u5eb7\u5723\u73af\u7403<\/b><\/p>\n

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\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n

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\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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