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\uff082\uff09\u957f\u6548\u4fc3\u7ea2\u7d20\uff08RD001\uff09\u5df2\u5b8c\u6210\u5728\u5065\u5eb7\u5fd7\u613f\u8005\u4e2d\u7684\u5242\u91cf\u9012\u589e\u7684\u5b89\u5168\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66I\u671f\u4e34\u5e8a\u7814\u7a76\u3002II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u53d7\u8bd5\u8005\u5165\u7ec4\u6b63\u5728\u8fdb\u884c\u4e2d\u3002<\/p>\n

\uff083\uff09\u6297IL-17A\u5355\u6297\uff08608\uff09\u5df2\u5b8c\u6210\u5065\u5eb7\u5fd7\u613f\u8005\u7684\u5242\u91cf\u9012\u589eI\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u6b63\u5728\u8fdb\u884c\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u60a3\u8005\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\uff084\uff09\u6297IL-5\u5355\u6297\uff08610\uff09\u5df2\u5b8c\u6210\u5065\u5eb7\u5fd7\u613f\u8005\u7684\u5242\u91cf\u9012\u589eI\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5373\u5c06\u542f\u52a8\u54ee\u5598\u60a3\u8005Ib\/II\u671f\u8bd5\u9a8c\u3002<\/p>\n

\uff085\uff09\u6297TNF-\u03b1\u5355\u6297\uff08SSS07\uff09\u5df2\u5b8c\u6210\u5065\u5eb7\u5fd7\u613f\u8005\u53ca\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u60a3\u8005I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\uff086\uff09\u6297VEGF\u5355\u6297\uff08601A\uff09\u5df2\u5b8c\u6210\u7528\u4e8e\u6cbb\u7597\u8001\u5e74\u6027\u9ec4\u6591\u53d8\u6027\uff08AMD\uff09\u53ca\u7cd6\u5c3f\u75c5\u9ec4\u6591\u6c34\u80bf(DME)\u60a3\u8005\u7684\u4e24\u9879\u5242\u91cf\u9012\u589e\u7684I\/IIa\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5df2\u542f\u52a8\u89c6\u7f51\u819c\u5206\u652f\u9759\u8109\u963b\u585e(BRVO)\u3001\u89c6\u7f51\u819c\u4e2d\u592eRVO\uff08CRVO\uff09\u53ca\u8fd1\u89c6\u7ee7\u53d1\u7684\u8109\u7edc\u819c\u65b0\u751f\u8840\u7ba1\u9002\u5e94\u75c7\uff08pmCNV\uff09\u60a3\u8005\u7684\u4e09\u9879II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\uff087\uff09\u6297EGFR\u5355\u6297\uff08602\uff09\u5df2\u5b8c\u6210602\u5206\u522b\u7528\u4e8e\u5065\u5eb7\u5fd7\u613f\u8005\u53ca\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u7684\u4e24\u9879I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u5df2\u542f\u52a8\u8be5\u4ea7\u54c1\u7528\u4e8e\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\uff088\uff09\u6297HER2\u5355\u6297\uff08302H\uff09\u8054\u5408602\u5728HER2\u9633\u6027\u3001KRAS\/NRAS\/BRAF\u91ce\u751f\u578b\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u7684I\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\uff0c\u6b64\u5916 302H\u8054\u5408\u6297CD47\u878d\u5408\u86cb\u767dIMM01\u6cbb\u7597HER2\u9633\u6027\u5b9e\u4f53\u7624\u3002<\/p>\n

6\u9879I\u671f\u4e34\u5e8a\u5f00\u53d1\u53caIND\u7533\u8bf7\u9636\u6bb5\u7684\u4ea7\u54c1\uff1a<\/b><\/p>\n

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\uff082\uff09\u6297IL-4R\u03b1\u5355\u6297\uff08611\uff09\u5df2\u5728\u7f8e\u56fd\u5b8c\u6210\u5bf9\u5065\u5eb7\u5fd7\u613f\u8005\u7684\u5242\u91cf\u9012\u589eI\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6b63\u5728\u4e2d\u56fd\u5bf9\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u542f\u52a8Ib\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\uff083\uff09\u6cbb\u7597\u8d2b\u8840\u7684HIF-117\uff08SSS17\uff09\u6b63\u5728\u8fdb\u884cI\u671f\u4e34\u5e8a\u8bd5\u9a8c\u60a3\u8005\u5165\u7ec4\u3002<\/p>\n

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\u622a\u6b622021\u5e746\u670831\u65e5\uff0c\u4e09\u751f\u5236\u836f\u62e5\u6709\u8fd13,000\u540d\u9500\u552e\u53ca\u8425\u9500\u4eba\u5458\uff0c\u4e1a\u52a1\u904d\u53ca\u5168\u56fd\u3002\u6b64\u5916\u7279\u6bd4\u6fb3\u3001\u76ca\u8d5b\u666e\u3001\u76ca\u6bd4\u5965\u3001\u8d5b\u535a\u5c14\u7b49\u4ea7\u54c1\u901a\u8fc7\u56fd\u9645\u5316\u63a8\u5e7f\u5df2\u8fdc\u9500\u81f3\u591a\u4e2a\u56fd\u5bb6\u3002<\/p>\n

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