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\u8f89\u51cc\u516c\u53f8\u4e2d\u56fd\u533a\u9996\u5e2d\u6267\u884c\u5b98Eric Breumier\u8868\u793a\uff1a\u201c\u8f89\u51cc\u81f4\u529b\u4e8e\u5f00\u53d1\u521b\u65b0\u836f\u7269\uff0c\u5e76\u5c06\u4ed6\u4eec\u5f15\u8fdb\u4e2d\u56fd\u3002\u6ce8\u5c04\u7528\u918b\u9178\u5730\u52a0\u745e\u514b2019\u5e74\u5728\u4e2d\u56fd\u7684\u4e0a\u5e02\uff0c\u5370\u8bc1\u4e86\u8f89\u51cc\u63d0\u9ad8\u521b\u65b0\u836f\u54c1\u53ef\u53ca\u6027\u7684\u52aa\u529b\u3002\u6211\u4eec\u575a\u4fe1\uff0c\u8f89\u745e\u662f\u6211\u4eec\u6700\u7406\u60f3\u7684\u5408\u4f5c\u4f19\u4f34\u3002\u4ee5\u5176\u5728\u80bf\u7624\u9886\u57df\u7684\u9886\u5bfc\u529b\u548c\u5353\u8d8a\u8868\u73b0\uff0c\u8f89\u745e\u4e0e\u8f89\u51cc\u7684\u5408\u4f5c\uff0c\u5c06\u60e0\u53ca\u56fd\u5185\u524d\u5217\u817a\u764c\u60a3\u8005\uff0c\u6ee1\u8db3\u4ed6\u4eec\u7684\u533b\u5b66\u9700\u6c42\u3002\u201d <\/p>\n

\u6ce8\u5c04\u7528\u918b\u9178\u5730\u52a0\u745e\u514b\u662f\u8f89\u51cc\u7814\u53d1\u7684\u4e00\u6b3e\u6cbb\u7597\u524d\u5217\u817a\u764c\u7684\u836f\u7269\uff0c\u4e8e2018\u5e749\u6708\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c2019\u5e74\u6b63\u5f0f\u5728\u4e2d\u56fd\u4e0a\u5e02\u9500\u552e\u3002\u4e0e\u76ee\u524d\u4e34\u5e8a\u5e38\u7528\u7684\u4fc3\u6027\u817a\u6fc0\u7d20\u91ca\u653e\u6fc0\u7d20\uff08GnRH\uff09\u6fc0\u52a8\u5242\u4e0d\u540c\uff0c\u6ce8\u5c04\u7528\u918b\u9178\u5730\u52a0\u745e\u514b\u662f\u4e2d\u56fd\u9996\u4e2a<\/span>\u4e0a\u5e02\u7684GnRH\u62ee\u6297\u5242\u521b\u65b0\u7597\u6cd5\uff0c\u4e0eGnRH \u6fc0\u52a8\u5242\u76f8\u6bd4\uff0c\u6ce8\u5c04\u7528\u918b\u9178\u5730\u52a0\u745e\u514b\u53ef\u4ee5\u5feb\u901f\u6709\u6548\u964d\u4f4e\u777e\u916e\u6c34\u5e73\uff0c\u800c\u4e0d\u4f1a\u51fa\u73b0\u777e\u916e\u4e00\u8fc7\u6027\u5347\u9ad8\u5bfc\u81f4\u7684\u201c\u53cd\u8df3\u201d\u73b0\u8c61[1]<\/sup>\u3002\u56e0\u6b64\u53ef\u4ee5\u663e\u8457\u63d0\u9ad8\u60a3\u8005\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\uff0c\u540c\u65f6\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027[2]<\/sup>\uff0c\u4e3a\u524d\u5217\u817a\u764c\u60a3\u8005\u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/p>\n

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[1]<\/sup> Klotz et al (2008) The ef\ufb01cacy and safety of Degarelix: a 12month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer. BJUI, 102, 1531-1538.
[2]<\/sup> \u65bd\u6653\u78ca, \u5468\u94c1, \u793c\u5d69, \u5b59\u9896\u6d69. GnRH\u62ee\u6297\u5242\u5728\u524d\u5217\u817a\u764c\u5185\u5206\u6ccc\u6cbb\u7597\u4e2d\u7684\u4e34\u5e8a\u5e94\u7528\u548c\u53d1\u5c55\u524d\u666f[J]. \u7b2c\u4e8c\u519b\u533b\u5927\u5b66\u5b66\u62a5, 2016, 37(012):1506-1511.
[3]<\/sup> \u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u6ccc\u5c3f\u7537\u751f\u6b96\u7cfb\u7edf\u80bf\u7624\u4e13\u4e1a\u59d4\u5458\u4f1a\u524d\u5217\u817a\u764c\u5b66\u7ec4.\u524d\u5217\u817a\u764c\u7b5b\u67e5\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082021\u5e74\u7248\uff09.\u4e2d\u56fd\u764c\u75c7\u6742\u5fd7[J].2021.31.5:435-440<\/p>\n

\u76f8\u5173\u94fe\u63a5 :<\/p>\n

http:\/\/www.pfizer.com.cn<\/p>\n","protected":false},"excerpt":{"rendered":"

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[1] Klotz et al (2008) The ef\ufb01cacy and safety of Degarelix: a 12month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer. BJUI, 102, 1531-1538.[2] \u65bd\u6653\u78ca, \u5468\u94c1, \u793c\u5d69, \u5b59\u9896\u6d69. GnRH\u62ee\u6297\u5242\u5728\u524d\u5217\u817a\u764c\u5185\u5206\u6ccc\u6cbb\u7597\u4e2d\u7684\u4e34\u5e8a\u5e94\u7528\u548c\u53d1\u5c55\u524d\u666f[J]. \u7b2c\u4e8c\u519b\u533b\u5927\u5b66\u5b66\u62a5, 2016, 37(012):1506-1511.[3] \u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u6ccc\u5c3f\u7537\u751f\u6b96\u7cfb\u7edf\u80bf\u7624\u4e13\u4e1a\u59d4\u5458\u4f1a\u524d\u5217\u817a\u764c\u5b66\u7ec4.\u524d\u5217\u817a\u764c\u7b5b\u67e5\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\uff082021\u5e74\u7248\uff09.\u4e2d\u56fd\u764c\u75c7\u6742\u5fd7[J].2021.31.5:435-440 \u76f8\u5173\u94fe\u63a5 : http:\/\/www.pfizer.com.cn… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":8278,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-41212","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/41212","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=41212"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/41212\/revisions"}],"predecessor-version":[{"id":41213,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/41212\/revisions\/41213"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/8278"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=41212"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=41212"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=41212"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}