{"id":40576,"date":"2021-08-09T20:45:00","date_gmt":"2021-08-09T13:45:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021080920450040576"},"modified":"2021-08-10T21:36:37","modified_gmt":"2021-08-10T13:36:37","slug":"ai%e8%b5%8b%e8%83%bdprotac%e7%a0%94%e5%8f%91%ef%bc%8c%e8%8b%b1%e7%9f%bd%e6%99%ba%e8%83%bd%e4%b8%8earvinas%e8%be%be%e6%88%90%e5%90%88%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021080920450040576","title":{"rendered":"AI\u8d4b\u80fdPROTAC\u7814\u53d1\uff0c\u82f1\u77fd\u667a\u80fd\u4e0eArvinas\u8fbe\u6210\u5408\u4f5c"},"content":{"rendered":"<p><p>\u9999\u6e2f2021\u5e748\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u82f1\u77fd\u667a\u80fd\uff08Insilico 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id=\"prni_dvprnejpg00f7left\" style=\"text-align: center;width: 100%\" dir=\"ltr\"><a href=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/insilico_medicine.jpg\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" id=\"prnejpg00f7left\" title=\"AI\u8d4b\u80fdPROTAC\u7814\u53d1\uff0c\u82f1\u77fd\u667a\u80fd\u4e0eArvinas\u8fbe\u6210\u5408\u4f5c\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/insilico_medicine.jpg\" alt=\"AI\u8d4b\u80fdPROTAC\u7814\u53d1\uff0c\u82f1\u77fd\u667a\u80fd\u4e0eArvinas\u8fbe\u6210\u5408\u4f5c\" align=\"middle\" border=\"0\" \/><\/a> <br \/> <span>AI\u8d4b\u80fdPROTAC\u7814\u53d1\uff0c\u82f1\u77fd\u667a\u80fd\u4e0eArvinas\u8fbe\u6210\u5408\u4f5c<\/span><\/div>\n<p>\u5728\u5df2\u88ab\u4eba\u7c7b\u89e3\u6790\u7684\u75be\u75c5\u76f8\u5173\u86cb\u767d\u4e2d\uff0c\u4f20\u7edf\u7684\u5c0f\u5206\u5b50\u548c\u6297\u4f53\u836f\u7269\u53ea\u80fd\u9776\u5411\u5927\u7ea620%\u7684\u86cb\u767d\uff0c\u5c1a\u6709\u9ad8\u8fbe80%\u7684\u86cb\u767d\u9776\u6807\u4e0d\u80fd\u88ab\u4f20\u7edf\u7684\u5c0f\u5206\u5b50\u6216\u5927\u5206\u5b50\u836f\u7269\u6240\u9776\u5411\uff0c\u5c5e\u4e8e&ldquo;\u4e0d\u53ef\u6210\u836f&rdquo;\u9776\u70b9\u3002PROTAC\u5373\u86cb\u767d\u6c34\u89e3\u9776\u5411\u5d4c\u5408\u4f53\uff0c\u63d0\u4f9b\u4e86\u4e00\u79cd\u65b0\u578b\u7684\u836f\u7269\u5f00\u53d1\u7b56\u7565\u3002\u5b83\u53ef\u4ee5\u964d\u89e3\u4f20\u7edf\u5c0f\u5206\u5b50\u7597\u6cd5&ldquo;\u4e0d\u53ef\u9776\u5411&rdquo;\u7684\u86cb\u767d\u8d28\uff0c\u4f7f\u9776\u70b9\u4ece&ldquo;\u65e0\u6210\u836f\u6027&rdquo;\u53d8\u6210&ldquo;\u6709\u6210\u836f\u6027&rdquo;\u3002Arvinas\u662f\u5168\u7403\u7b2c\u4e00\u4e2a\u5c06\u8fd0\u7528\u6b64\u6280\u672f\u7684\u836f\u7269\u63a8\u5411\u4e34\u5e8a\u9636\u6bb5\u7684\u516c\u53f8\u3002<\/p>\n<p>&ldquo;Arvinas\u662fPROTAC\u6280\u672f\u7684\u5148\u9a71\uff0c\u4e5f\u662f\u86cb\u767d\u8d28\u964d\u89e3\u7597\u6cd5\u7684\u5168\u7403\u9886\u5bfc\u8005\u3002\u6211\u4eec\u671f\u5f85\u4e0eArvinas\u5728\u86cb\u767d\u8d28\u964d\u89e3\u7597\u6cd5\u7684\u521b\u65b0\u9886\u57df\u5c55\u5f00\u5408\u4f5c\uff0c\u5e76\u5efa\u7acb\u6301\u4e45\u7684\u4f19\u4f34\u5173\u7cfb\u3002&rdquo;\u82f1\u77fd\u667a\u80fd\u521b\u59cb\u4eba\u3001\u533b\u5b66\u9996\u5e2d\u6267\u884c\u5b98Alex Zhavoronkov\u535a\u58eb\u8bf4\u3002<\/p>\n<p>\u4eca\u5e747\u6708\uff0c\u82f1\u77fd\u667a\u80fd\u5ba3\u5e03\u5b8c\u6210\u4e86<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=zh-hans&amp;o=3253436-1&amp;h=814956279&amp;u=https%3A%2F%2Fwww.prnasia.com%2Fstory%2F323211-1.shtml&amp;a=%E7%94%B1%E5%8D%8E%E5%B9%B3%E6%8A%95%E8%B5%84%EF%BC%88Warburg+Pincus%EF%BC%89%E7%89%B5%E5%A4%B4%E7%9A%842.55%E4%BA%BF%E7%BE%8E%E5%85%83%E8%9E%8D%E8%B5%84\" rel=\"nofollow noopener\" target=\"_blank\">\u7531\u534e\u5e73\u6295\u8d44\uff08Warburg Pincus\uff09\u7275\u5934\u76842.55\u4ebf\u7f8e\u5143\u878d\u8d44<\/a>\uff0c\u5e76\u5438\u5f15\u8d85\u8fc725\u5bb6\u77e5\u540d\u6295\u8d44\u8005\u52a0\u5165\u30028\u6708\uff0c<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=zh-hans&amp;o=3253436-1&amp;h=2421133648&amp;u=https%3A%2F%2Fwww.prnasia.com%2Fstory%2F328167-1.shtml&amp;a=%E8%AF%A5%E5%85%AC%E5%8F%B8%E6%8F%90%E5%90%8D%E4%BA%86%E7%AC%AC%E4%BA%8C%E4%B8%AA%E8%82%BE%E7%BA%A4%E7%BB%B4%E5%8C%96%E4%B8%B4%E5%BA%8A%E5%89%8D%E5%80%99%E9%80%89%E8%8D%AF%E7%89%A9\" rel=\"nofollow noopener\" target=\"_blank\">\u8be5\u516c\u53f8\u63d0\u540d\u4e86\u7b2c\u4e8c\u4e2a\u80be\u7ea4\u7ef4\u5316\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269<\/a>\u3002&nbsp;<\/p>\n<p>&ldquo;\u4e0eArvinas\u7684\u5408\u4f5c\u5bf9\u82f1\u77fd\u667a\u80fd\u6765\u8bf4\u5177\u6709\u5212\u65f6\u4ee3\u7684\u610f\u4e49\uff0c\u5b83\u6807\u5fd7\u7740\u516c\u53f8\u4ee5Chemistry42\u4e3a\u4ee3\u8868\u7684\u751f\u6210\u5316\u5b66\u4eba\u5de5\u667a\u80fd\u5e73\u53f0\u8fdb\u4e00\u6b65\u62d3\u5c55\u5230\u86cb\u767d\u964d\u89e3\u7597\u6cd5\uff08PROTAC\uff09\u8fd9\u4e00\u65b0\u5174\u9886\u57df\uff0c\u5e76\u88ab\u8be5\u9886\u57df\u5168\u7403\u9886\u5148\u7684\u5934\u90e8\u4f01\u4e1a\u6240\u8ba4\u53ef\u3002\u672a\u6765\u53cc\u65b9\u4f1a\u5bc6\u5207\u5408\u4f5c\uff0c\u5171\u540c\u81f4\u529b\u4e8e\u628a\u4eba\u5de5\u667a\u80fd\u4e0ePROTAC\u6280\u672f\u76f8\u7ed3\u5408\u66f4\u9ad8\u6548\u7684\u4e3a\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u63d0\u4f9b\u98a0\u8986\u6027\u7684\u89e3\u51b3\u65b9\u6848\u3002&rdquo; \u82f1\u77fd\u667a\u80fd\u9996\u5e2d\u79d1\u5b66\u5b98\u3001\u836f\u7269\u7814\u53d1\u8d1f\u8d23\u4eba\u4efb\u5cf0\u535a\u58eb\u8bf4\u3002<\/p>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>http:\/\/insilicomedicine.com<\/p>\n<p>https:\/\/insilico.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9999\u6e2f2021\u5e748\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u82f1\u77fd\u667a\u80fd\uff08Insilico Medicine\uff09\u5168\u7403\u9886\u5148\u7684\u3001\u5229\u7528\u7aef\u5230\u7aef\u4eba\u5de5\u667a\u80fd\u8fdb\u884c\u9776\u70b9\u53d1\u73b0\uff0c\u5c0f\u5206\u5b50\u5316\u5b66\u548c\u4e34\u5e8a\u7814\u53d1\u7684\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u5e03\u5c06\u4e0eArvinas\uff08NASDAQ:ARVN\uff09\u643a\u624b\u5f00\u53d1\u65b0\u578bPROTAC\u7597\u6cd5\u3002\u8be5\u5408\u4f5c\u57fa\u4e8e\u82f1\u77fd\u667a\u80fd\u5f3a\u5927\u7684\u4eba\u5de5\u667a\u80fd\u5e73\u53f0\uff0c\u4ee5\u53ca\u53cc\u65b9\u79d1\u7814\u56e2\u961f\u5728\u65b0\u578bPROTAC\u7597\u6cd5\u65b9\u9762\u7684\u5bc6\u5207\u5408\u4f5c\u3002\u6b64\u6b21\u5408\u4f5c\u5c06\u9488\u5bf9\u73b0\u6709\u9776\u70b9\u548c\u4e0b\u4e00\u4ee3\u9776\u70b9\uff0c\u901a\u8fc7\u4eba\u5de5\u667a\u80fd\u9884\u6d4b\u4e09\u5143\u590d\u5408\u7269\u7684\u7ed3\u6784\u5305\u62ec\u86cb\u767d\u4e0e\u86cb\u767d\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u6765\u8bbe\u8ba1PROTAC\u5206\u5b50\uff0c\u4ee5\u5c55\u793a\u4eba\u5de5\u667a\u80fd\u4e0e\u836f\u7269\u53d1\u73b0\u6700\u91cd\u8981\u7684\u524d\u6cbf\u6280\u672f\u4e4b\u4e00PROTAC\u76f8\u7ed3\u5408\u5e26\u6765\u7684\u7a81\u7834\u3002 AI\u8d4b\u80fdPROTAC\u7814\u53d1\uff0c\u82f1\u77fd\u667a\u80fd\u4e0eArvinas\u8fbe\u6210\u5408\u4f5c 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&ldquo;Arvinas\u662fPROTAC\u6280\u672f\u7684\u5148\u9a71\uff0c\u4e5f\u662f\u86cb\u767d\u8d28\u964d\u89e3\u7597\u6cd5\u7684\u5168\u7403\u9886\u5bfc\u8005\u3002\u6211\u4eec\u671f\u5f85\u4e0eArvinas\u5728\u86cb\u767d\u8d28\u964d\u89e3\u7597\u6cd5\u7684\u521b\u65b0\u9886\u57df\u5c55\u5f00\u5408\u4f5c\uff0c\u5e76\u5efa\u7acb\u6301\u4e45\u7684\u4f19\u4f34\u5173\u7cfb\u3002&rdquo;\u82f1\u77fd\u667a\u80fd\u521b\u59cb\u4eba\u3001\u533b\u5b66\u9996\u5e2d\u6267\u884c\u5b98Alex Zhavoronkov\u535a\u58eb\u8bf4\u3002 \u4eca\u5e747\u6708\uff0c\u82f1\u77fd\u667a\u80fd\u5ba3\u5e03\u5b8c\u6210\u4e86\u7531\u534e\u5e73\u6295\u8d44\uff08Warburg Pincus\uff09\u7275\u5934\u76842.55\u4ebf\u7f8e\u5143\u878d\u8d44\uff0c\u5e76\u5438\u5f15\u8d85\u8fc725\u5bb6\u77e5\u540d\u6295\u8d44\u8005\u52a0\u5165\u30028\u6708\uff0c\u8be5\u516c\u53f8\u63d0\u540d\u4e86\u7b2c\u4e8c\u4e2a\u80be\u7ea4\u7ef4\u5316\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269\u3002&nbsp; &ldquo;\u4e0eArvinas\u7684\u5408\u4f5c\u5bf9\u82f1\u77fd\u667a\u80fd\u6765\u8bf4\u5177\u6709\u5212\u65f6\u4ee3\u7684\u610f\u4e49\uff0c\u5b83\u6807\u5fd7\u7740\u516c\u53f8\u4ee5Chemistry42\u4e3a\u4ee3\u8868\u7684\u751f\u6210\u5316\u5b66\u4eba\u5de5\u667a\u80fd\u5e73\u53f0\u8fdb\u4e00\u6b65\u62d3\u5c55\u5230\u86cb\u767d\u964d\u89e3\u7597\u6cd5\uff08PROTAC\uff09\u8fd9\u4e00\u65b0\u5174\u9886\u57df\uff0c\u5e76\u88ab\u8be5\u9886\u57df\u5168\u7403\u9886\u5148\u7684\u5934\u90e8\u4f01\u4e1a\u6240\u8ba4\u53ef\u3002\u672a\u6765\u53cc\u65b9\u4f1a\u5bc6\u5207\u5408\u4f5c\uff0c\u5171\u540c\u81f4\u529b\u4e8e\u628a\u4eba\u5de5\u667a\u80fd\u4e0ePROTAC\u6280\u672f\u76f8\u7ed3\u5408\u66f4\u9ad8\u6548\u7684\u4e3a\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u63d0\u4f9b\u98a0\u8986\u6027\u7684\u89e3\u51b3\u65b9\u6848\u3002&rdquo; \u82f1\u77fd\u667a\u80fd\u9996\u5e2d\u79d1\u5b66\u5b98\u3001\u836f\u7269\u7814\u53d1\u8d1f\u8d23\u4eba\u4efb\u5cf0\u535a\u58eb\u8bf4\u3002 \u76f8\u5173\u94fe\u63a5 : http:\/\/insilicomedicine.com https:\/\/insilico.com&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2021080920450040576\">Read 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