{"id":38481,"date":"2021-07-23T07:00:00","date_gmt":"2021-07-23T00:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021072307000038481"},"modified":"2021-07-23T21:37:18","modified_gmt":"2021-07-23T13:37:18","slug":"%e5%a4%a9%e6%bc%94%e5%ae%a3%e5%b8%83%e4%b8%8e%e9%bb%98%e6%b2%99%e4%b8%9c%e5%85%ac%e5%8f%b8%e5%bc%80%e5%b1%95%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e5%90%88%e4%bd%9c%ef%bc%8c%e4%bb%a5%e6%8e%a8%e8%bf%9b","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021072307000038481","title":{"rendered":"\u5929\u6f14\u5ba3\u5e03\u4e0e\u9ed8\u6c99\u4e1c\u516c\u53f8\u5f00\u5c55\u4e34\u5e8a\u8bd5\u9a8c\u5408\u4f5c\uff0c\u4ee5\u63a8\u8fdb\u4e24\u4e2a\u6297CTLA-4\u5355\u514b\u9686\u6297\u4f53\u9879\u76ee\uff08ADG116 \u548c ADG126\uff09\u4e0eKEYTRUDA\u00ae\uff08\u5e15\u535a\u5229\u73e0\u5355\u6297\uff09\u8054\u5408\u6cbb\u7597"},"content":{"rendered":"<p><p><span class=\"xn-subheadline\">\u5c06\u542f\u52a8\u4e24\u9879\u8bc4\u4f30 NEObody &#x2122; \u5019\u9009\u4ea7\u54c1 ADG116 \u548c SAFEbody &#x2122; 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Co., Inc.\u7684\u5b50\u516c\u53f8&nbsp;Merck Sharp &amp; Dohme Corp<\/p>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>https:\/\/investor.adagene.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5c06\u542f\u52a8\u4e24\u9879\u8bc4\u4f30 NEObody &#x2122; \u5019\u9009\u4ea7\u54c1 ADG116 \u548c SAFEbody &#x2122; \u5019\u9009\u4ea7\u54c1 ADG126 \u4e0e KEYTRUDA \u00ae\uff08\u5e15\u535a\u5229\u73e0\u5355\u6297\uff09\u8054\u5408\u6cbb\u7597\u665a\u671f\/\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u60a3\u8005\u7684\u5168\u7403\u4e34\u5e8a\u7814\u7a76\u8bd5\u9a8c \u82cf\u5dde2021\u5e747\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u5929\u6f14\u836f\u4e1a\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u516c\u53f8\u201d\u6216\u201c\u5929\u6f14\u201d\uff09\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aADAG\uff09\u662f\u4e00\u5bb6\u5e73\u53f0\u9a71\u52a8\u7684\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u53d1\u73b0\u5e76\u5f00\u53d1\u4ee5\u539f\u521b\u6297\u4f53\u4e3a\u57fa\u77f3\u7684\u65b0\u578b\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u3002\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03\uff0c\u4e0e\u5e02\u573a\u4e0a\u9876\u5c16\u7684\u514d\u75ab\u80bf\u7624\u5b66(IO)\u836f\u7269\u9886\u5bfc\u8005\u9ed8\u6c99\u4e1c\uff08\u9ed8\u6c99\u4e1c\u662f\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u80af\u5c3c\u6c83\u65af\u5e02\u9ed8\u514b\u516c\u53f8\u7684\u516c\u53f8\u5546\u53f7\uff09\u8fbe\u6210\u4e86\u4e34\u5e8a\u8bd5\u9a8c\u5408\u4f5c\u548c\u4f9b\u836f\u534f\u8bae\uff0c\u53cc\u65b9\u5c31\u5929\u6f14\u836f\u4e1a\u7684\u6297&nbsp;CTLA-4 \u5355\u514b\u9686\u6297\u4f53&nbsp;(mAb) \u5019\u9009\u4ea7\u54c1&nbsp;ADG116 \u548c&nbsp;ADG126\u4e0e\u9ed8\u6c99\u4e1c\u7684\u6297&nbsp;PD-1 \u836f\u7269KEYTRUDA&reg;\uff08\u5e15\u535a\u5229\u73e0\u5355\u6297\uff09\u7684\u8054\u5408\u6cbb\u7597\u5c06\u542f\u52a8\u4e24\u9879\u5f00\u653e\u6807\u7b7e\u3001\u5242\u91cf\u9012\u589e\u4e0e\u62d3\u5c55\u7814\u7a76\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u8bc4\u4f30\u8be5\u8054\u5408\u7528\u836f\u5728\u665a\u671f\/\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u60a3\u8005\u4e2d\u7684\u4e34\u5e8a\u7597\u6548\u3002 \u201c\u4e0e\u9ed8\u6c99\u4e1c\u7684\u6b64\u6b21\u5408\u4f5c\u4ee5\u53ca\u79ef\u6781\u63a8\u8fdb\u6211\u4eec\u7684\u5168\u7403\u4e34\u5e8a\u7814\u7a76\uff0c\u662f\u5929\u6f14\u6297CTLA-4\u7597\u6cd5\u5f00\u53d1\u8ba1\u5212\u4e2d\u7684\u4e00\u4e2a\u91cd\u8981\u91cc\u7a0b\u7891\uff0c\u201d\u5929\u6f14\u8054\u5408\u521b\u59cb\u4eba\u3001\u9996\u5e2d\u6267\u884c\u5b98\u517c\u8463\u4e8b\u957f\u7f57\u57f9\u5fd7\u535a\u58eb\u8868\u793a\uff0c\u201cADG116\u548cADG126\u662f\u5229\u7528\u5929\u6f14\u4eba\u5de5\u667a\u80fd\u6297\u4f53\u53d1\u73b0\u5e73\u53f0\u81ea\u4e3b\u7814\u53d1\u7684\u4e24\u6b3e\u9ad8\u5ea6\u5dee\u5f02\u5316\u7684\u6297CTLA-4\u4ea7\u54c1\u3002NEObody&#x2122; 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