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\u8be5\u5408\u4f5c\u5efa\u7acb\u5728\u4e92\u8865\u4f18\u52bf\u57fa\u7840\u4e0a\uff0c\u4ee5\u63a8\u8fdb \u4ee5 2 \u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u4e3a\u4e3b\u7684\u9ed1\u8272\u7d20\u7624\u7814\u7a76<\/span><\/p>\n\n\n\n
\"\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u6bd4\u5229\u65f6\u5e03\u9c81\u585e\u5c14\u548c\u6cd5\u56fd\u5361\u65af\u7279\u5c142021\u5e747\u67081\u65e5 \/\u7f8e\u901a\u793e\/ — \u6b27\u6d32\u764c\u75c7\u7814\u7a76\u4e0e\u6cbb\u7597\u7ec4\u7ec7 (EORTC) \u4e0e Pierre Fabre \u4eca\u65e5\u5ba3\u5e03\u5efa\u7acb\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\uff0c\u4e3a\u5df2\u884c\u5207\u9664\u672f\u7684 2 \u671f BRAF<\/i> \u7a81\u53d8\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u63d0\u4f9b\u652f\u6301\u3002\u8be5\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u5305\u62ec\u89c4\u5212\u3001\u8bbe\u8ba1\u548c\u6267\u884c\u4e00\u9879\u5927\u578b\u7684\u4e34\u5e8a 3 \u671f\u7814\u7a76\uff0c\u4ee5\u7814\u7a76\u5982\u4f55\u4f7f\u7528 BRAF \u548c MEK \u9776\u5411\u7597\u6cd5\u964d\u4f4e\u8fd9\u4e00\u60a3\u8005\u7fa4\u4f53\u7684\u590d\u53d1\u98ce\u9669\uff0c\u76ee\u524d\u6b63\u7b49\u5f85\u5f53\u5c40\u6279\u51c6\u3002 <\/p>\n

\u201c\u9057\u61be\u7684\u662f\uff0c\u5982\u4eca\u6709\u5f88\u591a2 \u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u5373\u4f7f\u5df2\u5207\u9664\u80bf\u7624\uff0c\u4f46\u764c\u75c7\u4ecd\u7136\u590d\u53d1\u3002\u8fdb\u4e00\u6b65\u4e86\u89e3\u6709\u6548\u6cbb\u7597\u5bf9\u590d\u53d1\u7684\u5f71\u54cd\u81f3\u5173\u91cd\u8981\uff0c\u201d<\/i>EORTC \u9996\u5e2d\u6267\u884c\u5b98 Denis Lacombe \u535a\u58eb\u8bf4\u3002\u201c\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u4e0e<\/i> Pierre Fabre <\/i>\u5408\u4f5c\uff0c\u4ed6\u4eec\u4e3a\u8be5\u6cbb\u7597\u9886\u57df\u5e26\u6765\u4e86\u6df1\u539a\u7684\u5e95\u8574\u4e0e\u5f3a\u5927\u7684\u4e13\u4e1a\u77e5\u8bc6\uff0c\u80fd\u4e3a<\/i> 2 <\/i>\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u5e26\u6765\u771f\u6b63\u7684\u6539\u53d8\u3002\u201d<\/i><\/p>\n

\u201cPierre Fabre<\/span> <\/i>\u4e0e<\/i> EORTC <\/i>\u4e4b\u95f4\u7684\u5408\u4f5c\u662f\u6211\u4eec\u7684\u533b\u7597\u548c\u4e34\u5e8a\u80fd\u529b\u4e0e\u9886\u5148\u7684\u5168\u7403\u80bf\u7624\u7814\u7a76\u7f51\u7edc\u4e4b\u95f4\u7684\u5b8c\u7f8e\u7ec4\u5408\u3002\u6211\u4eec\u5f3a\u5927\u7684\u4e92\u8865\u4e13\u4e1a\u77e5\u8bc6\u6709\u53ef\u80fd\u6539\u53d8\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u7684\u62a4\u7406\u201d\uff0c<\/i>Pierre Fabre<\/span> \u6267\u884c\u526f\u603b\u88c1\u517c\u533b\u60a3\u4e2d\u5fc3\u90e8\u4e3b\u7ba1 Deborah Szafir \u535a\u58eb\u8bf4\u3002\u201c\u6211\u4eec\u5728\u4e00\u9879\u5f00\u521b\u6027\u4e34\u5e8a<\/i> 3 <\/i>\u671f\u7814\u7a76\u4e2d\u7684\u6218\u7565\u5408\u4f5c\u5173\u7cfb\u8bc1\u5b9e\u4e86<\/i> Pierre Fabre <\/i>\u5bf9\u80bf\u7624\u5b66\uff0c\u7279\u522b\u662f\u5bf9\u76ae\u80a4\u764c\u7684\u7814\u53d1\u627f\u8bfa\u3002\u6211\u4eec\u5173\u4e8e<\/i> BRAF <\/i>\u548c<\/i> MEK <\/i>\u6291\u5236\u5242\u7684\u4e13\u4e1a\u77e5\u8bc6\u5728\u4e0d\u65ad\u589e\u957f\uff0c\u5e0c\u671b\u80fd\u501f\u6b64\u4e3a\u76ae\u80a4\u764c\u60a3\u8005\u63d0\u4f9b\u66f4\u5f3a\u529b\u7684\u652f\u6301\u3002\u201d<\/i><\/p>\n

Pierre Fabre<\/span> \u957f\u671f\u81f4\u529b\u4e8e\u9ed1\u8272\u7d20\u7624\u9886\u57df\uff0c\u5e76\u901a\u8fc7\u7ed3\u5408\u80bf\u7624\u5b66\u3001\u76ae\u80a4\u5b66\u548c\u76ae\u80a4\u5316\u5986\u54c1\u65b9\u9762\u7684\u4e13\u4e1a\u77e5\u8bc6\uff0c\u91c7\u7528\u72ec\u7279\u7684\u6574\u4f53\u6027\u7597\u6cd5\u5b9e\u73b0\u76ae\u80a4\u5065\u5eb7\u3002EORTC \u662f\u6c47\u805a\u4e86\u5168\u7403 2800 \u540d\u4e34\u5e8a\u764c\u75c7\u7814\u7a76\u4e13\u5bb6\u7684\u7f51\u7edc\uff0c\u4e0e Pierre Fabre \u4e00\u6837\u81f4\u529b\u4e8e\u63d0\u9ad8\u764c\u75c7\u60a3\u8005\u7684\u6cbb\u7597\u6c34\u5e73\u3002 <\/p>\n

\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee EORTC \u7f51\u7ad9 (www.eortc.org<\/a>) \u4e0e Pierre Fabre \u7f51\u7ad9 (www.pierre-fabre.com<\/a>) – @PierreFabre\u3002<\/p>\n

\u53c2\u8003\u6587\u732e<\/b><\/p>\n[1] Neoplasma. 2016;63(4):510-7. doi: 10.4149\/neo_2016_403. 
[2] American Cancer Society. What Causes Melanoma Skin Cancer. Available at: https:\/\/www.cancer.org\/cancer\/melanoma-skin-cancer\/causes-risks-prevention\/what-causes.html<\/a>. Accessed June 2021<\/span>.
[3] International Agency for Research on Cancer. Melanoma of skin. Available at: https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/16-Melanoma-of-skin-fact-sheet.pdf.<\/a> Accessed June 2021<\/span>.
[4] Klein O, et al. Eur J Cancer 2013;49:1073\u20131079.
[5] Melanoma UK. 2020 Melanoma Skin Cancer Report. Available at: https:\/\/www.melanomauk.org.uk\/2020-melanoma-skin-cancer-report<\/a>. Accessed June 2021<\/span>.<\/p>\n","protected":false},"excerpt":{"rendered":"

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\u53c2\u8003\u6587\u732e [1] Neoplasma. 2016;63(4):510-7. doi:… Read 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