{"id":33476,"date":"2021-06-09T07:00:00","date_gmt":"2021-06-09T00:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021060907000033476"},"modified":"2021-06-09T21:36:46","modified_gmt":"2021-06-09T13:36:46","slug":"%e5%be%b7%e7%90%aa%e5%8c%bb%e8%8d%af%e5%90%88%e4%bd%9c%e4%bc%99%e4%bc%b4%e5%85%ac%e5%b8%83eltanexor%e6%b2%bb%e7%96%97%e5%8e%bb%e7%94%b2%e5%9f%ba%e5%8c%96%e8%8d%af%e7%89%a9%e9%9a%be%e6%b2%bb%e7%9a%84","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021060907000033476","title":{"rendered":"\u5fb7\u742a\u533b\u836f\u5408\u4f5c\u4f19\u4f34\u516c\u5e03Eltanexor\u6cbb\u7597\u53bb\u7532\u57fa\u5316\u836f\u7269\u96be\u6cbb\u7684\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81\u7684\u6700\u65b0\u4e34\u5e8a\u6570\u636e"},"content":{"rendered":"\n\n\n
\"\"<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

—<\/b>\u5728<\/b>15<\/b>\u4f8b\u53ef\u8bc4\u4f30\u7597\u6548\u7684\u60a3\u8005\u4e2d\uff0c<\/b>7<\/b>\u4f8b\uff08<\/b>47%<\/b>\uff09\u8fbe\u5230\u9aa8\u9ad3\u5b8c\u5168\u7f13\u89e3\uff0c<\/b>5<\/b>\u4f8b\uff08<\/b>33%<\/b>\uff09\u75be\u75c5\u7a33\u5b9a<\/b>, <\/b>\u603b\u75be\u75c5\u63a7\u5236\u7387\u8fbe<\/b>80%–<\/b><\/p>\n

—<\/b>\u9aa8\u9ad3\u5b8c\u5168\u7f13\u89e3\u60a3\u8005\u7684\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u660e\u663e\u4f18\u4e8e\u672a\u8fbe\u5230\u9aa8\u9ad3\u5b8c\u5168\u7f13\u89e3\u6216\u75be\u75c5\u8fdb\u5c55\u7684\u60a3\u8005<\/b>—<\/b><\/p>\n

\u4e0a\u6d77\u548c\u9999\u6e2f2021\u5e746\u67089\u65e5 \/\u7f8e\u901a\u793e\/ — \u5fb7\u742a\u533b\u836f\u5408\u4f5c\u4f19\u4f34Karyopharm Therapeutics Inc.\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aKPTI\uff09\u57282021\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\uff0c\u516c\u5e03\u4e86eltanexor\u6cbb\u7597\u53bb\u7532\u57fa\u5316\u836f\u7269\uff08HMA)\u96be\u6cbb\u7684\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81\uff08MDS\uff09\u7684\u6700\u65b0\u4e34\u5e8a\u6570\u636e\u3002<\/p>\n

\n<\/p><\/div>\n

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\u53bb\u7532\u57fa\u5316\u836f\u7269\u96be\u6cbb\u7684MDS\u60a3\u8005\u6cbb\u7597\u9009\u62e9\u6709\u9650\u4e14\u9884\u540e\u8f83\u5dee\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff08mOS\uff09\u4ec5\u4e3a4-6\u4e2a\u6708\u3002Eltanexor\u662f\u65b0\u4e00\u4ee3\u53e3\u670dXPO1\u6291\u5236\u5242\uff0c\u5728\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u663e\u793a\u51fa\u8f83\u585e\u5229\u5c3c\u7d22\uff08\u7b2c\u4e00\u4ee3XPO1\u6291\u5236\u5242\uff09\u66f4\u5f3a\u7684\u6297\u80bf\u7624\u6d3b\u6027\u53ca\u66f4\u4f4e\u7684\u8840\u8111\u5c4f\u969c\u6e17\u900f\u3002\u56e0\u6b64\uff0celtanexor\u53ef\u4ee5\u5b9e\u73b0\u66f4\u597d\u7684\u7ed9\u836f\u9891\u6b21\uff0c\u540c\u65f6\u51cf\u8f7b\u4e2d\u67a2\u6027\u6076\u5fc3\u3002<\/p>\n

\u5fb7\u742a\u533b\u836f\u5df2\u4e0eKaryopharm\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u83b7\u5f97eltanexor\u7b49\u56db\u6b3e\u5019\u9009\u836f\u7269\u572817\u4e2a\u4e9a\u592a\u5e02\u573a\u7684\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u6743\u76ca\u3002\u76ee\u524d\uff0c\u5fb7\u742a\u533b\u836f\u6b63\u4e8e\u4e2d\u56fd\u5f00\u5c55eltanexor\u6cbb\u7597MDS\u53ca\u665a\u671f\u5b9e\u4f53\u7624\u60a3\u8005\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5176\u4e2d\uff0c<\/b>eltanexor<\/b>\u6cbb\u7597<\/b>MDS<\/b>\u60a3\u8005\u7684\u4e00\u9879<\/b>I\/II<\/b>\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08<\/b>HATCH<\/b>\uff09\u5df2\u7ecf\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/b><\/p>\n

\u5173\u4e8e<\/b>Eltanexor<\/b>\uff08<\/b>ATG-016<\/b>\uff09<\/b><\/p>\n

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\u5173\u4e8e\u5fb7\u742a\u533b\u836f<\/b><\/p>\n

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\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n

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<\/div>\n

\u76f8\u5173\u94fe\u63a5 :<\/p>\n

http:\/\/www.antengene.com<\/p>\n","protected":false},"excerpt":{"rendered":"

—\u572815\u4f8b\u53ef\u8bc4\u4f30\u7597\u6548\u7684\u60a3\u8005\u4e2d\uff0c7\u4f8b\uff0847%\uff09\u8fbe\u5230\u9aa8\u9ad3\u5b8c\u5168\u7f13\u89e3\uff0c5\u4f8b\uff0833%\uff09\u75be\u75c5\u7a33\u5b9a, \u603b\u75be\u75c5\u63a7\u5236\u7387\u8fbe80%– —\u9aa8\u9ad3\u5b8c\u5168\u7f13\u89e3\u60a3\u8005\u7684\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u660e\u663e\u4f18\u4e8e\u672a\u8fbe\u5230\u9aa8\u9ad3\u5b8c\u5168\u7f13\u89e3\u6216\u75be\u75c5\u8fdb\u5c55\u7684\u60a3\u8005— \u4e0a\u6d77\u548c\u9999\u6e2f2021\u5e746\u67089\u65e5 \/\u7f8e\u901a\u793e\/ — \u5fb7\u742a\u533b\u836f\u5408\u4f5c\u4f19\u4f34Karyopharm Therapeutics 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