{"id":32980,"date":"2021-06-04T17:00:00","date_gmt":"2021-06-04T10:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021060417000032980"},"modified":"2021-06-05T21:36:53","modified_gmt":"2021-06-05T13:36:53","slug":"%e6%b3%9b%e7%94%9f%e5%ad%9016%e9%a1%b9%e7%99%8c%e7%97%87%e9%a2%86%e5%9f%9f%e7%a0%94%e7%a9%b6%e6%88%90%e6%9e%9c%e4%ba%ae%e7%9b%b82021%e7%be%8e%e5%9b%bd%e4%b8%b4%e5%ba%8a%e8%82%bf%e7%98%a4%e5%ad%a6","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021060417000032980","title":{"rendered":"\u6cdb\u751f\u5b5016\u9879\u764c\u75c7\u9886\u57df\u7814\u7a76\u6210\u679c\u4eae\u76f82021\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u5e74\u4f1a(ASCO)"},"content":{"rendered":"

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\u4f18\u5316\u4e34\u5e8a\u5e38\u89c4\u8bca\u65ad\u65b9\u6cd5<\/b><\/p>\n

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\u901a\u8fc7\u8d85\u58f0\u548c\u8d85\u58f0\u5f15\u5bfc\u4e0b\u7684\u7ec6\u9488\u7a7f\u523a\u6d3b\u68c0\uff08FNA\uff09\u662f\u5224\u65ad\u7532\u72b6\u817a\u826f\u6076\u6027\u7ed3\u8282\u7684\u4e3b\u8981\u65b9\u6cd5\u3002\u5bf9\u4e8eFNA\u65e0\u6cd5\u660e\u786e\u8bca\u65ad\u7684\u60a3\u8005\uff0c\u6cdb\u751f\u5b50\u4f9d\u6258\u201c\u4e00\u6b65\u6cd5\u201d\u5f00\u53d1\u4e86\u7532\u72b6\u817a\u764c\u5168\u5468\u671f\u57fa\u56e0\u68c0\u6d4b\u3002\u7814\u7a76#e15028\u521d\u6b65\u6570\u636e\u8868\u660e\u8be5\u4ea7\u54c1\u53ef\u8f85\u52a9\u533a\u5206\u7532\u72b6\u817a\u7ed3\u8282\u826f\u6076\u6027\uff0c\u4e3a\u6cbb\u7597\u51b3\u7b56\u63d0\u4f9b\u53c2\u8003\u4f9d\u636e\u3002<\/p>\n

\u63a2\u7d22\u57fa\u56e0\u7a81\u53d8\u53ca\u878d\u5408\u5206\u5e03\u7279\u5f81<\/b><\/p>\n

\u4e03\u9879\u7814\u7a76\uff08#e21577\u3001#e16143\u3001#e16042\u3001#8573\u3001#e21074\u3001#3055\u3001#4121\uff09\u5206\u522b\u5bf9\u9ed1\u8272\u7d20\u7624\u3001\u80c6\u56ca\u764c\u3001\u98df\u7ba1\u764c\u3001\u80f8\u817a\u7624\u3001\u80ba\u764c\u3001\u7532\u72b6\u817a\u764c\u3001\u80f0\u817a\u764c\u8fdb\u884c\u7a81\u53d8\u3001\u878d\u5408\u7279\u5f81\u591a\u7ef4\u5ea6\u63a2\u7d22\uff0c\u5bfb\u627e\u6f5c\u5728\u7cbe\u51c6\u6cbb\u7597\u9776\u70b9\u3001\u8010\u836f\u9776\u70b9\u53ca\u6709\u6548\u5e94\u5bf9\u63aa\u65bd\u3002<\/p>\n

\u63a2\u7d22\u514d\u75ab\u6cbb\u7597\u6807\u5fd7\u7269\u5206\u5e03\u7279\u5f81<\/b><\/p>\n

\u4e94\u9879\u7814\u7a76\uff08#2606\u3001#2586\u3001#e14575\u3001#e14576\u3001#2587\uff09\u5206\u522b\u63a2\u8ba8\u4e86POLE\/POLD1\u7a81\u53d8\u3001HMTs\u529f\u80fd\u7f3a\u5931\u7a81\u53d8\u3001TMB\u53ca\u8d85\u7a81\u53d8\u3001MSI\u3001KMT2C\/D\u529f\u80fd\u7f3a\u5931\u7a81\u53d8\u5728\u591a\u764c\u79cd\u4eba\u7fa4\u4e2d\u7684\u5206\u5e03\u7279\u5f81\u53ca\u5176\u5bf9\u514d\u75ab\u6cbb\u7597\u7597\u6548\u7684\u9884\u6d4b\u4f5c\u7528\uff0c\u4e3a\u514d\u75ab\u6cbb\u7597\u63d0\u4f9b\u542f\u793a\u3002<\/p>\n

\u63a2\u7d22\u9057\u4f20\u6027\u80bf\u7624\u6807\u5fd7\u7269\u5206\u5e03\u7279\u5f81<\/b><\/p>\n

\u7814\u7a76#e20511\u901a\u8fc7\u5bf9\u80ba\u764c\u60a3\u8005\u80da\u7cfb\u7a81\u53d8\u7684\u6df1\u5165\u5206\u6790\uff0c\u63a2\u8ba8\u4e86\u9057\u4f20\u56e0\u7d20\u4e0e\u80ba\u764c\u53d1\u5c55\u7684\u76f8\u5173\u6027\uff0c\u6709\u52a9\u4e8e\u9610\u660e\u80ba\u764c\u7684\u53d1\u75c5\u673a\u5236\uff0c\u52a9\u529b\u80ba\u764c\u7684\u53ca\u65e9\u53d1\u73b0\u53ca\u8bca\u65ad\uff0c\u5e76\u4e3a\u5176\u9884\u9632\u53ca\u9776\u5411\u6cbb\u7597\u63d0\u4f9b\u7b56\u7565\u3002<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u7f16\u53f7<\/b><\/span><\/p>\n<\/td>\n

\n

\u9898\u76ee<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

2586<\/span><\/p>\n<\/td>\n

\n

The predictive values of loss-of-function variants in histone methyltransferases for response to immune checkpoint inhibitors in solid tumors<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

2587<\/span><\/p>\n<\/td>\n

\n

Association of KMT2C\/D loss-of-function mutations with tumor infiltrating lymphocytes and response to immune checkpoint inhibitors in solid tumors<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

2606<\/span><\/p>\n<\/td>\n

\n

Investigating the various predictive values of POLE\/POLD1 mutations for response to immune checkpoint inhibitors (ICIs) in different solid tumors<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

3055<\/span><\/p>\n<\/td>\n

\n

Differences of US-FNA BSRTC class, postoperative pathology and mutation landscape of thyroid nodules between China and other countries<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

4121<\/span><\/p>\n<\/td>\n

\n

Genomic profiling of KRAS wide-type pancreatic ductal adenocarcinomas identifies targetable genetic alterations<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

8573<\/span><\/p>\n<\/td>\n

\n

Myasthenia gravis-associated thymoma and myasthenia gravis-free thymoma have distinct somatic mutation and gene expression profiles<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e14575<\/span><\/p>\n<\/td>\n

\n

Exploration of the TMB and hypermutation Landscape in Chinese pan-Cancer patient by NEXT-GENERATION SEQUENCING<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e14576<\/span><\/p>\n<\/td>\n

\n

Exploration of the MSI landscape in Chinese pan-cancer patient by NEXT-GENERATION SEQUENCING<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e15028<\/span><\/p>\n<\/td>\n

\n

Significance of molecular detection in diagnosis of benign and malignant thyroid nodules in China<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e16143<\/span><\/p>\n<\/td>\n

\n

Evaluation of somatic and germline mutations in Chinese patients with gallbladder carcinoma reveals clinically actionable targets<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e16042<\/span><\/p>\n<\/td>\n

\n

Genomic profiling of esophageal squamous cell carcinoma reveals actionable genetic alterations<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e16500<\/span><\/p>\n<\/td>\n

\n

Accuracy of an urine-based liquid biopsy genetic test in detecting renal pelvic cancer<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e16509<\/span><\/p>\n<\/td>\n

\n

A multicenter, prospective evaluation of a urine-based assay for bladder cancer diagnosis<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e20511<\/span><\/p>\n<\/td>\n

\n

Genomic features of lung cancer patients harboring germlinemutations associated with hereditary cancer syndromes<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e21074<\/span><\/p>\n<\/td>\n

\n

Identification of RET fusion as mechanisms of resistance toEGFR tyrosine-kinase inhibitors<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

e21577<\/span><\/p>\n<\/td>\n

\n

Genetic landscape of melanoma in China reveals enrichment of fusions in driver-negative melanoma<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n

 <\/p>\n

\u5173\u4e8e\u6cdb\u751f\u5b50<\/b><\/p>\n

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\u5b89\u5168\u6e2f\u58f0\u660e<\/b><\/p>\n

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